(Q38578680)

4 September 2017

0 references

Premature aging/senescence in cancer cells facing therapy: good or bad? (English)

1 reference

4 September 2017

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26330289%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

author name string

Llilians Calvo Gonzalez

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26330289%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

Sabrina Ghadaouia

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26330289%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

Aurélie Martinez

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26330289%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

publication date

2 September 2015

1 reference

4 September 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26330289%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

volume

17

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26330289%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

issue

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26330289%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

page(s)

71-87

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26330289%20AND%20SRC:MED&resulttype=core&format=json

https://scigraph.springernature.com/pub.10.1007/s10522-015-9593-9

1 June 2020

exact match

0 references

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Tumour biology: senescence in premalignant tumours

21 January 2018

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21 January 2018

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Senescence-associated secretory phenotypes reveal cell-nonautonomous functions of oncogenic RAS and the p53 tumor suppressor

21 January 2018

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The senescence-associated secretory phenotype: the dark side of tumor suppression

21 January 2018

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A human-like senescence-associated secretory phenotype is conserved in mouse cells dependent on physiological oxygen

21 January 2018

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Tumor suppressor and aging biomarker p16(INK4a) induces cellular senescence without the associated inflammatory secretory phenotype

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21 January 2018

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An essential role for senescent cells in optimal wound healing through secretion of PDGF-AA

21 January 2018

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DNA damage triggers a prolonged p53-dependent G1 arrest and long-term induction of Cip1 in normal human fibroblasts

21 January 2018

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21 January 2018

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A biomarker that identifies senescent human cells in culture and in aging skin in vivo

21 January 2018

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Translational research in oncology--10 years of progress and future prospects

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21 January 2018

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Adriamycin-induced senescence in breast tumor cells involves functional p53 and telomere dysfunction

21 January 2018

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Decreased skp2 expression is necessary but not sufficient for therapy-induced senescence in prostate cancer

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Dexamethasone reduces sensitivity to cisplatin by blunting p53-dependent cellular senescence in non-small cell lung cancer

21 January 2018

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DNA damage-mediated induction of a chemoresistant niche

21 January 2018

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Rapid induction of senescence in human cervical carcinoma cells

21 January 2018

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Identification of a specific telomere terminal transferase activity in Tetrahymena extracts

21 January 2018

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Mammalian telomeres end in a large duplex loop

21 January 2018

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Skp2 is oncogenic and overexpressed in human cancers

21 January 2018

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Role of p21 in apoptosis and senescence of human colon cancer cells treated with camptothecin

21 January 2018

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Hallmarks of Cancer: The Next Generation

21 January 2018

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Telomeres shorten during ageing of human fibroblasts

21 January 2018

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pRB plays an essential role in cell cycle arrest induced by DNA damage

21 January 2018

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The serial cultivation of human diploid cell strains

21 January 2018

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Immune surveillance of senescent cells--biological significance in cancer- and non-cancer pathologies

21 January 2018

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Suppression of induced pluripotent stem cell generation by the p53-p21 pathway

21 January 2018

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Distinct epigenetic changes in the stromal cells of breast cancers

21 January 2018

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p53-mediated senescence impairs the apoptotic response to chemotherapy and clinical outcome in breast cancer.

21 January 2018

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p53-Dependent accelerated senescence induced by ionizing radiation in breast tumour cells

21 January 2018

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Senescence surveillance of pre-malignant hepatocytes limits liver cancer development.

21 January 2018

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Linking the p53 tumour suppressor pathway to somatic cell reprogramming

21 January 2018

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Pluripotent stem cells escape from senescence-associated DNA methylation changes

21 January 2018

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Plasminogen activator inhibitor-1 is a critical downstream target of p53 in the induction of replicative senescence

21 January 2018

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Ink4a/Arf expression is a biomarker of aging

21 January 2018

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Senescence of activated stellate cells limits liver fibrosis

21 January 2018

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Oncogene-induced senescence relayed by an interleukin-dependent inflammatory network

21 January 2018

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The essence of senescence

21 January 2018

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Induction of p38δ expression plays an essential role in oncogenic ras-induced senescence

21 January 2018

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Epithelial-mesenchymal transition induced by senescent fibroblasts

21 January 2018

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Mitochondrial DNA damage induces apoptosis in senescent cells

21 January 2018

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Senescence-associated beta-galactosidase is lysosomal beta-galactosidase

21 January 2018

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p53 Deficiency leads to compensatory up-regulation of p16INK4a

21 January 2018

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Epigenetic silencing of IRF7 and/or IRF5 in lung cancer cells leads to increased sensitivity to oncolytic viruses

21 January 2018

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The Ink4/Arf locus is a barrier for iPS cell reprogramming

21 January 2018

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Premature senescence involving p53 and p16 is activated in response to constitutive MEK/MAPK mitogenic signaling

21 January 2018

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Skp2 targeting suppresses tumorigenesis by Arf-p53-independent cellular senescence

21 January 2018

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Senescent human fibroblasts increase the early growth of xenograft tumors via matrix metalloproteinase secretion

21 January 2018

1 reference

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Targeting aurora kinases limits tumour growth through DNA damage-mediated senescence and blockade of NF-κB impairs this drug-induced senescence.

21 January 2018

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Modulation of mammalian life span by the short isoform of p53.

21 January 2018

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DDR-mediated crosstalk between DNA-damaged cells and their microenvironment.

21 January 2018

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A p53-mediated DNA damage response limits reprogramming to ensure iPS cell genomic integrity

21 January 2018

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p53 deficiency enhances mitotic arrest and slippage induced by pharmacological inhibition of Aurora kinases

21 January 2018

1 reference

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BRAFE600-associated senescence-like cell cycle arrest of human naevi

21 January 2018

1 reference

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21 January 2018

p53 mutations in cancer

1 reference

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Cellular senescence: from physiology to pathology

21 January 2018

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The first molecular details of ALT in human tumor cells

21 January 2018

1 reference

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Rb-mediated heterochromatin formation and silencing of E2F target genes during cellular senescence

21 January 2018

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Protein kinase C: structure, function, and regulation

21 January 2018

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Tumor suppressor maspin is up-regulated during keratinocyte senescence, exerting a paracrine antiangiogenic activity

21 January 2018

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Malignant transformation of neurofibromas in neurofibromatosis 1 is associated with CDKN2A/p16 inactivation

21 January 2018

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Radiation to stromal fibroblasts increases invasiveness of pancreatic cancer cells through tumor-stromal interactions

21 January 2018

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S-Phase-specific activation of PKC alpha induces senescence in non-small cell lung cancer cells.

21 January 2018

1 reference

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A theory of marginotomy. The incomplete copying of template margin in enzymic synthesis of polynucleotides and biological significance of the phenomenon

21 January 2018

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Stromal fibroblasts in cancer: a novel tumor-promoting cell type

21 January 2018

1 reference

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Reprogramming to pluripotency: stepwise resetting of the epigenetic landscape

21 January 2018

1 reference

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Oxygen sensitivity severely limits the replicative lifespan of murine fibroblasts

21 January 2018

1 reference

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Stromal-epithelial interactions in aging and cancer: senescent fibroblasts alter epithelial cell differentiation

21 January 2018

1 reference

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Feedback between p21 and reactive oxygen production is necessary for cell senescence

21 January 2018

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DEC1, a basic helix-loop-helix transcription factor and a novel target gene of the p53 family, mediates p53-dependent premature senescence

21 January 2018

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Four faces of cellular senescence.

21 January 2018

1 reference

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Persistent DNA damage signalling triggers senescence-associated inflammatory cytokine secretion.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-015-9593-9

DNA-SCARS: distinct nuclear structures that sustain damage-induced senescence growth arrest and inflammatory cytokine secretion

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-015-9593-9

Aging increases p16 INK4a expression in vascular smooth-muscle cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-015-9593-9

Mitogen stimulation cooperates with telomere shortening to activate DNA damage responses and senescence signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-015-9593-9

Replicative senescence of activated human hepatic stellate cells is accompanied by a pronounced inflammatory but less fibrogenic phenotype

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-015-9593-9

The identification of senescence-specific genes during the induction of senescence in prostate cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-015-9593-9

Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-015-9593-9

Telomeres, stem cells, senescence, and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-015-9593-9

Microarray analysis of replicative senescence

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-015-9593-9

Shaping genetic alterations in human cancer: the p53 mutation paradigm

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-015-9593-9

Senescence is a developmental mechanism that contributes to embryonic growth and patterning

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-015-9593-9

Rescue of key features of the p63-null epithelial phenotype by inactivation of Ink4a and Arf.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-015-9593-9

Treatment-induced damage to the tumor microenvironment promotes prostate cancer therapy resistance through WNT16B.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-015-9593-9

Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-015-9593-9

p53 mutant mice that display early ageing-associated phenotypes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-015-9593-9

The multistep nature of cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-015-9593-9

Oncogenic BRAF induces senescence and apoptosis through pathways mediated by the secreted protein IGFBP7.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-015-9593-9

Sequential activation of the MEK-extracellular signal-regulated kinase and MKK3/6-p38 mitogen-activated protein kinase pathways mediates oncogenic ras-induced premature senescence

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-015-9593-9

Enhanced killing of therapy-induced senescent tumor cells by oncolytic measles vaccine viruses

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-015-9593-9

Papillomavirus E2 induces senescence in HPV-positive cells via pRB- and p21(CIP)-dependent pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-015-9593-9

Senescence and tumour clearance is triggered by p53 restoration in murine liver carcinomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-015-9593-9

Real-time in vivo imaging of p16Ink4a reveals cross talk with p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-015-9593-9

The chemokine growth-regulated oncogene 1 (Gro-1) links RAS signaling to the senescence of stromal fibroblasts and ovarian tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-015-9593-9

Sunitinib induces apoptosis and growth arrest of medulloblastoma tumor cells by inhibiting STAT3 and AKT signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-015-9593-9

Therapeutic targeting of replicative immortality

21 January 2018

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p16INK4a modulates p53 in primary human mammary epithelial cells.

21 January 2018

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Sunitinib induces cellular senescence via p53/Dec1 activation in renal cell carcinoma cells

21 January 2018

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The Achilles' heel of senescent cells: from transcriptome to senolytic drugs.

21 January 2018

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Expression of the p16INK4a tumor suppressor versus other INK4 family members during mouse development and aging.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-015-9593-9

PKCη promotes senescence induced by oxidative stress and chemotherapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-015-9593-9

Frequent somatic mutations in PTEN and TP53 are mutually exclusive in the stroma of breast carcinomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10522-015-9593-9