(Q38759968)

6 September 2017

p53 induces formation of NEAT1 lncRNA-containing paraspeckles that modulate replication stress response and chemosensitivity (English)

1 reference

6 September 2017

19

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6 September 2017

Jasmine Barra

3

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Carmen Adriaens

Carmen Adriaens

1

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Eleonora Leucci

Eleonora Leucci

11

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Anna Sablina

Anna A Sablina

17

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Tetsuro Hirose

Tetsuro Hirose

16

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William Vermi

William Vermi

10

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Jean-Christophe Marine

Jean-Christophe Marine

21

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Diether Lambrechts

18

Diether Lambrechts

1 reference

6 September 2017

15

Shinichi Nakagawa

1 reference

6 September 2017

20

Cédric Blanpain

1 reference

6 September 2017

4

Mathilde Latil

1 reference

6 September 2017

Laura Standaert

2

1 reference

6 September 2017

Annelien Verfaillie

5

1 reference

6 September 2017

Peter Kalev

6

1 reference

6 September 2017

Bram Boeckx

7

1 reference

6 September 2017

Paul W G Wijnhoven

8

1 reference

6 September 2017

Enrico Radaelli

9

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6 September 2017

Gaëlle Lapouge

12

1 reference

6 September 2017

Benjamin Beck

13

1 reference

6 September 2017

Joost van den Oord

14

1 reference

6 September 2017

language of work or name

English

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publication date

4 July 2016

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6 September 2017

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6 September 2017

22

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6 September 2017

8

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6 September 2017

861-868

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https://scigraph.springernature.com/pub.10.1038/nm.4135

6 September 2017

0 references

cites work

Surfing the p53 network

1 reference

How stem cells age and why this makes us grow old.

21 January 2018

1 reference

In vivo activation of the p53 pathway by small-molecule antagonists of MDM2

21 January 2018

1 reference

Drugging the p53 pathway: understanding the route to clinical efficacy

21 January 2018

1 reference

Another fork in the road--life or death decisions by the tumour suppressor p53

21 January 2018

1 reference

Pharmacologic p53 activation blocks cell cycle progression but fails to induce senescence in epithelial cancer cells

21 January 2018

1 reference

The GENCODE v7 catalog of human long noncoding RNAs: analysis of their gene structure, evolution, and expression

21 January 2018

1 reference

Xist RNA is a potent suppressor of hematologic cancer in mice

21 January 2018

1 reference

Differentiation of mammary tumors and reduction in metastasis upon Malat1 lncRNA loss

21 January 2018

1 reference

A large intergenic noncoding RNA induced by p53 mediates global gene repression in the p53 response

21 January 2018

1 reference

Extensive and coordinated transcription of noncoding RNAs within cell-cycle promoters

21 January 2018

1 reference

Pint lincRNA connects the p53 pathway with epigenetic silencing by the Polycomb repressive complex 2

21 January 2018

1 reference

p53-dependent non-coding RNA networks in chronic lymphocytic leukemia.

21 January 2018

1 reference

iRegulon: from a gene list to a gene regulatory network using large motif and track collections

21 January 2018

1 reference

i-cisTarget: an integrative genomics method for the prediction of regulatory features and cis-regulatory modules

21 January 2018

1 reference

An architectural role for a nuclear noncoding RNA: NEAT1 RNA is essential for the structure of paraspeckles

21 January 2018

1 reference

A triple helix stabilizes the 3' ends of long noncoding RNAs that lack poly(A) tails

21 January 2018

1 reference

Altered nuclear retention of mRNAs containing inverted repeats in human embryonic stem cells: functional role of a nuclear noncoding RNA

21 January 2018

1 reference

MENepsilon/beta noncoding RNAs are essential for structural integrity of nuclear paraspeckles

21 January 2018

1 reference

MEN epsilon/beta nuclear-retained non-coding RNAs are up-regulated upon muscle differentiation and are essential components of paraspeckles

21 January 2018

1 reference

The p53 network: cellular and systemic DNA damage responses in aging and cancer

21 January 2018

1 reference

Genomic landscape of carcinogen-induced and genetically induced mouse skin squamous cell carcinoma

21 January 2018

1 reference

Identifying the cellular origin of squamous skin tumors

21 January 2018

1 reference

Paraspeckles are subpopulation-specific nuclear bodies that are not essential in mice

21 January 2018

1 reference

Replication stress and cancer

21 January 2018

1 reference

The stress-activated protein kinases p38α/β and JNK1/2 cooperate with Chk1 to inhibit mitotic entry upon DNA replication arrest

21 January 2018

1 reference

Maintaining genome stability at the replication fork

21 January 2018

1 reference

Exploiting replicative stress to treat cancer

21 January 2018

1 reference

ATM and MET kinases are synthetic lethal with nongenotoxic activation of p53.

21 January 2018

1 reference

Multi-gene expression predictors of single drug responses to adjuvant chemotherapy in ovarian carcinoma: predicting platinum resistance.

21 January 2018

1 reference

Integrated genomic analyses of ovarian carcinoma

21 January 2018

1 reference

The oestrogen receptor alpha-regulated lncRNA NEAT1 is a critical modulator of prostate cancer

21 January 2018

1 reference

Tumor hypoxia induces nuclear paraspeckle formation through HIF-2α dependent transcriptional activation of NEAT1 leading to cancer cell survival.

21 January 2018

1 reference

Long noncoding RNA NEAT1 promotes glioma pathogenesis by regulating miR-449b-5p/c-Met axis

21 January 2018

1 reference

p53: traffic cop at the crossroads of DNA repair and recombination

21 January 2018

1 reference

The p53 pathway: positive and negative feedback loops

21 January 2018

1 reference

Wip1 directly dephosphorylates gamma-H2AX and attenuates the DNA damage response

21 January 2018

1 reference

Wild-type p53-induced phosphatase 1 dephosphorylates histone variant gamma-H2AX and suppresses DNA double strand break repair

21 January 2018

1 reference

gamma-H2AX dephosphorylation by protein phosphatase 2A facilitates DNA double-strand break repair

21 January 2018

1 reference

PARP-1 dependent recruitment of the amyotrophic lateral sclerosis-associated protein FUS/TLS to sites of oxidative DNA damage.

21 January 2018

1 reference

PARP activation regulates the RNA-binding protein NONO in the DNA damage response to DNA double-strand breaks

21 January 2018

1 reference

Sequences in PSF/SFPQ mediate radioresistance and recruitment of PSF/SFPQ-containing complexes to DNA damage sites in human cells

21 January 2018

1 reference

Involvement of Matrin 3 and SFPQ/NONO in the DNA damage response

21 January 2018

1 reference

The RNA-binding protein fused in sarcoma (FUS) functions downstream of poly(ADP-ribose) polymerase (PARP) in response to DNA damage

21 January 2018

1 reference

Liquid demixing of intrinsically disordered proteins is seeded by poly(ADP-ribose).

21 January 2018

1 reference

RNA Processing and Genome Stability: Cause and Consequence

21 January 2018

1 reference

DNA damage triggers SAF-A and RNA biogenesis factors exclusion from chromatin coupled to R-loops removal.

21 January 2018

1 reference

ATM-dependent chromatin changes silence transcription in cis to DNA double-strand breaks

21 January 2018

1 reference

A Single Conserved Residue Mediates Binding of the Ribonucleotide Reductase Catalytic Subunit RRM1 to RRM2 and Is Essential for Mouse Development.

21 January 2018

1 reference

The lncRNA Neat1 is required for corpus luteum formation and the establishment of pregnancy in a subpopulation of mice.

21 January 2018

1 reference

The long noncoding RNA Neat1 is required for mammary gland development and lactation.

21 January 2018

1 reference

Tumor spectrum analysis in p53-mutant mice

21 January 2018

1 reference

The magical touch: genome targeting in epidermal stem cells induced by tamoxifen application to mouse skin

21 January 2018

1 reference

Multi-stage chemical carcinogenesis in mouse skin: fundamentals and applications

21 January 2018

1 reference

TopHat: discovering splice junctions with RNA-Seq

21 January 2018

1 reference

HTSeq--a Python framework to work with high-throughput sequencing data

21 January 2018

1 reference

GENCODE: the reference human genome annotation for The ENCODE Project

21 January 2018

1 reference

Differential expression analysis for sequence count data

21 January 2018

1 reference

Model-based analysis of ChIP-Seq (MACS)

21 January 2018

1 reference

Cytoscape 2.8: new features for data integration and network visualization

21 January 2018

1 reference

The building process of the functional paraspeckle with long non-coding RNAs

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27376578

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Clinical implication of long non-coding RNA NEAT1 expression in hepatocellular carcinoma patients

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27376578

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Upregulation and clinicopathological significance of long non-coding NEAT1 RNA in NSCLC tissues

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27376578

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NM.4135

1 reference

6 September 2017

1 reference