(Q39060497)

8 September 2017

title

Cellular senescence in renal ageing and disease (English)

1 reference

8 September 2017

1 reference

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28029153%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

5

Jan M van Deursen

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28029153%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

4

Darren J Baker

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28029153%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

author name string

Ines Sturmlechner

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28029153%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

Cynthia J Sieben

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28029153%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

language of work or name

English

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publication date

28 December 2016

1 reference

Nature Reviews Nephrology

8 September 2017

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28029153%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

volume

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28029153%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

issue

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28029153%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

page(s)

77-89

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28029153%20AND%20SRC:MED&resulttype=core&format=json

https://scigraph.springernature.com/pub.10.1038/nrneph.2016.183

9 June 2020

exact match

0 references

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Senescence is a developmental mechanism that contributes to embryonic growth and patterning

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An essential role for senescent cells in optimal wound healing through secretion of PDGF-AA

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Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a

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Opposing roles for p16Ink4a and p19Arf in senescence and ageing caused by BubR1 insufficiency

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Clearance of p16Ink4a-positive senescent cells delays ageing-associated disorders

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Senescent stroma promotes prostate cancer progression: the role of miR-210.

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Senescence surveillance of pre-malignant hepatocytes limits liver cancer development.

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p53-dependent chemokine production by senescent tumor cells supports NKG2D-dependent tumor elimination by natural killer cells

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Senescence and tumour clearance is triggered by p53 restoration in murine liver carcinomas

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Non-cell-autonomous tumor suppression by p53.

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The role of senescent cells in ageing

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Naturally occurring p16(Ink4a)-positive cells shorten healthy lifespan

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Human skin fibroblasts in vitro differentiate along a terminal cell lineage

21 January 2018

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A new regulatory motif in cell-cycle control causing specific inhibition of cyclin D/CDK4

21 January 2018

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Proliferating cell nuclear antigen and p21 are components of multiple cell cycle kinase complexes

21 January 2018

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Persistent DNA damage signalling triggers senescence-associated inflammatory cytokine secretion.

21 January 2018

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The matricellular protein CCN1 induces fibroblast senescence and restricts fibrosis in cutaneous wound healing

21 January 2018

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The senescence-associated secretory phenotype: the dark side of tumor suppression

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Upregulation of chicken p15INK4b at senescence and in the developing brain.

21 January 2018

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Programmed cell death in animal development and disease

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Senescent cardiac fibroblast is critical for cardiac fibrosis after myocardial infarction

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Senescence of activated stellate cells limits liver fibrosis

21 January 2018

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Cellular senescence: from physiology to pathology

21 January 2018

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NKG2D ligands mediate immunosurveillance of senescent cells

21 January 2018

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INK4a knockout mice exhibit increased fibrosis under normal conditions and in response to unilateral ureteral obstruction

21 January 2018

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Autophagy Induces Prosenescent Changes in Proximal Tubular S3 Segments

21 January 2018

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Autophagy mediates the mitotic senescence transition

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRNEPH.2016.183

The DNA damage response induces inflammation and senescence by inhibiting autophagy of GATA4.

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRNEPH.2016.183

Autophagy plays a critical role in kidney tubule maintenance, aging and ischemia-reperfusion injury.

21 January 2018

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Autophagy protects the proximal tubule from degeneration and acute ischemic injury.

21 January 2018

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Cellular senescence limits regenerative capacity and allograft survival.

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRNEPH.2016.183

The power and the promise of oncogene-induced senescence markers.

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRNEPH.2016.183

The differential impact of p16(INK4a) or p19(ARF) deficiency on cell growth and tumorigenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2016.183

p21 loss blocks senescence following Apc loss and provokes tumourigenesis in the renal but not the intestinal epithelium

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRNEPH.2016.183

VHL loss actuates a HIF-independent senescence programme mediated by Rb and p400.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2016.183

Autophagy and senescence in cancer-associated fibroblasts metabolically supports tumor growth and metastasis via glycolysis and ketone production

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2016.183

Selection of p53-Deficient Stromal Cells in the Tumor Microenvironment

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2016.183

The chemokine growth-regulated oncogene 1 (Gro-1) links RAS signaling to the senescence of stromal fibroblasts and ovarian tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2016.183

Monitoring tumorigenesis and senescence in vivo with a p16(INK4a)-luciferase model

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2016.183

Effects of aging on the common lymphoid progenitor to pro-B cell transition

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2016.183

Molecular inflammation: underpinnings of aging and age-related diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2016.183

p38 MAPK signaling underlies a cell-autonomous loss of stem cell self-renewal in skeletal muscle of aged mice

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRNEPH.2016.183

Rejuvenation of the muscle stem cell population restores strength to injured aged muscles

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2016.183

Autophagy maintains stemness by preventing senescence

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2016.183

Telomerase Deficiency Causes Alveolar Stem Cell Senescence-associated Low-grade Inflammation in Lungs.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2016.183

Senescent intimal foam cells are deleterious at all stages of atherosclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2016.183

Pancreatic beta cell senescence contributes to the pathogenesis of type 2 diabetes in high-fat diet-induced diabetic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2016.183

Accelerated senescence of endothelial progenitor cells in hypertension is related to the reduction of calcitonin gene-related peptide

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2016.183

Endothelial progenitor cell senescence is accelerated in both experimental hypertensive rats and patients with essential hypertension

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2016.183

Hypertension induces somatic cellular senescence in rats and humans by induction of cell cycle inhibitor p16INK4a

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2016.183

Telomere shortening and cellular senescence in a model of chronic renal allograft rejection

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2016.183

Synthetic lethal metabolic targeting of cellular senescence in cancer therapy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2016.183

Ionizing radiation-induced long-term expression of senescence markers in mice is independent of p53 and immune status

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2016.183

Effect of ionizing radiation induced damage of endothelial progenitor cells in vascular regeneration.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2016.183

Effects of aging on glomerular function and number in living kidney donors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2016.183

The association between age and nephrosclerosis on renal biopsy among healthy adults

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2016.183

Nephron hypertrophy and glomerulosclerosis and their association with kidney function and risk factors among living kidney donors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2016.183

Characteristics of renal cystic and solid lesions based on contrast-enhanced computed tomography of potential kidney donors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2016.183

Age, kidney function, and risk factors associate differently with cortical and medullary volumes of the kidney

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2016.183

Clinical characteristics of potential kidney donors with asymptomatic kidney stones

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2016.183

Longitudinal studies on the rate of decline in renal function with age.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2016.183

Kidney aging--inevitable or preventable?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2016.183

New insights on molecular mechanisms of renal aging

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2016.183

Increased cellular senescence and vascular rarefaction exacerbate the progression of kidney fibrosis in aged mice following transient ischemic injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2016.183

In vivo and in vitro analysis of age-associated changes and somatic cellular senescence in renal epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2016.183

21 January 2018

Fibrosis and renal aging

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2016.183

Cellular senescence in pretransplant renal biopsies predicts postoperative organ function.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2016.183

Molecular aspects of renal senescence

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2016.183

Mechanisms and consequences of injury and repair in older organ transplants

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2016.183

Ink4a/Arf expression is a biomarker of aging

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2016.183

Expression of p16INK4a and other cell cycle regulator and senescence associated genes in aging human kidney

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2016.183

Tubular cell senescence and expression of TGF-beta1 and p21(WAF1/CIP1) in tubulointerstitial fibrosis of aging rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2016.183

Cell senescence in rat kidneys in vivo increases with growth and age despite lack of telomere shortening.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2016.183

Accelerated senescence of renal tubular epithelial cells is associated with disease progression of patients with immunoglobulin A (IgA) nephropathy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2016.183

Accelerated senescence in the kidneys of patients with type 2 diabetic nephropathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2016.183

Markers of cellular senescence in zero hour biopsies predict outcome in renal transplantation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2016.183

Effects of donor age and cell senescence on kidney allograft survival.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2016.183

Macrophage involvement in the kidney repair phase after ischaemia/reperfusion injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2016.183

Incidence and mortality of acute renal failure in Medicare beneficiaries, 1992 to 2001.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2016.183

Mechanisms of maladaptive repair after AKI leading to accelerated kidney ageing and CKD.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2016.183

Cell cycle arrest and the evolution of chronic kidney disease from acute kidney injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2016.183

Aging aggravates long-term renal ischemia-reperfusion injury in a rat model

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2016.183

Idiopathic IgA nephropathy: pathogenesis, histopathology, and therapeutic options

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2016.183

Proteins induced by telomere dysfunction are associated with human IgA nephropathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2016.183

Diabetes and altered glucose metabolism with aging

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2016.183

HMGA2 expression in white adipose tissue linking cellular senescence with diabetes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2016.183

Pathogenesis of diabetic nephropathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2016.183

Diabetic kidney disease: from physiology to therapeutics

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2016.183

Hyperglycemia causes cellular senescence via a SGLT2- and p21-dependent pathway in proximal tubules in the early stage of diabetic nephropathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2016.183

Erk 1,2 phosphorylates p27(Kip1): Functional evidence for a role in high glucose-induced hypertrophy of mesangial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2016.183

High glucose-induced hypertrophy of mesangial cells requires p27(Kip1), an inhibitor of cyclin-dependent kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2016.183

Downregulation of connexin 43 expression by high glucose induces senescence in glomerular mesangial cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2016.183

p27(Kip1) Knockout mice are protected from diabetic nephropathy: evidence for p27(Kip1) haplotype insufficiency

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2016.183

Autosomal dominant polycystic kidney disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2016.183

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2016.183

Genetics and pathogenesis of polycystic kidney disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2016.183

p21 is decreased in polycystic kidney disease and leads to increased epithelial cell cycle progression: roscovitine augments p21 levels

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2016.183

Long-lasting arrest of murine polycystic kidney disease with CDK inhibitor roscovitine.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2016.183

Disparate effects of roscovitine on renal tubular epithelial cell apoptosis and senescence: implications for autosomal dominant polycystic kidney disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2016.183

Nephronophthisis: disease mechanisms of a ciliopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2016.183

Loss of Glis2/NPHP7 causes kidney epithelial cell senescence and suppresses cyst growth in the Kif3a mouse model of cystic kidney disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2016.183

Distinguishing age-related from disease-related glomerulosclerosis on kidney biopsy: the Aging Kidney Anatomy study

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2016.183

Chronic kidney disease and premature ageing

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2016.183

A novel model of adenine-induced tubulointerstitial nephropathy in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2016.183

Feline chronic kidney disease is associated with shortened telomeres and increased cellular senescence

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2016.183

Mesenchymal stem cells from rats with chronic kidney disease exhibit premature senescence and loss of regenerative potential

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2016.183

Chronic health conditions in adult survivors of childhood cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2016.183

Induction of p21WAF1/CIP1/SDI1 in kidney tubule cells affects the course of cisplatin-induced acute renal failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2016.183

The induction of cell cycle regulatory and DNA repair proteins in cisplatin-induced acute renal failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2016.183

Aging increases the susceptibility of cisplatin-induced nephrotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2016.183

Cellular senescence in aging and age-related disease: from mechanisms to therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2016.183

Targeted drug delivery to renal proximal tubule epithelial cells mediated by 2-glucosamine.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2016.183

Renal Targeting: Peptide-Based Drug Delivery to Proximal Tubule Cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2016.183

Angiotensin II receptor blocker attenuates intrarenal renin-angiotensin-system and podocyte injury in rats with myocardial infarction

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2016.183

Aldosterone/Mineralocorticoid receptor stimulation induces cellular senescence in the kidney.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2016.183

Targeting kidney mesangium by nanoparticles of defined size

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2016.183

Nanomedicines for renal disease: current status and future applications

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2016.183

Immunoliposome targeting to mesangial cells: a promising strategy for specific drug delivery to the kidney

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2016.183

siRNA targeted to p53 attenuates ischemic and cisplatin-induced acute kidney injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2016.183

Anti-Inflamm-Aging Effects of Long-Term Caloric Restriction via Overexpression of SIGIRR to Inhibit NF-κB Signaling Pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2016.183

Short-term calorie restriction protects against renal senescence of aged rats by increasing autophagic activity and reducing oxidative damage.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2016.183

AMPK and mTOR in cellular energy homeostasis and drug targets

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2016.183

mTOR inhibition prevents epithelial stem cell senescence and protects from radiation-induced mucositis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2016.183

Expression and mechanism of mammalian target of rapamycin in age-related renal cell senescence and organ aging

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2016.183

Metformin-mediated increase in DICER1 regulates microRNA expression and cellular senescence

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2016.183

Metformin induces suppression of NAD(P)H oxidase activity in podocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2016.183

Metformin prevents experimental gentamicin-induced nephropathy by a mitochondria-dependent pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2016.183

Metformin Protects Against Cisplatin-Induced Tubular Cell Apoptosis and Acute Kidney Injury via AMPKα-regulated Autophagy Induction

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2016.183

Immune surveillance of senescent cells--biological significance in cancer- and non-cancer pathologies

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2016.183

Clearance of senescent cells by ABT263 rejuvenates aged hematopoietic stem cells in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2016.183

Directed elimination of senescent cells by inhibition of BCL-W and BCL-XL

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2016.183

The flavonoid quercetin in disease prevention and therapy: facts and fancies

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2016.183

In vitro activity of Bcr-Abl inhibitors AMN107 and BMS-354825 against clinically relevant imatinib-resistant Abl kinase domain mutants

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2016.183

The Achilles' heel of senescent cells: from transcriptome to senolytic drugs.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2016.183

Mitogen-activated protein kinase p38 defines the common senescence-signalling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2016.183

Control of the senescence-associated secretory phenotype by NF-κB promotes senescence and enhances chemosensitivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2016.183

Suppression of the senescence-associated secretory phenotype (SASP) in human fibroblasts using small molecule inhibitors of p38 MAP kinase and MK2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2016.183

MTOR regulates the pro-tumorigenic senescence-associated secretory phenotype by promoting IL1A translation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2016.183

Metformin inhibits the senescence-associated secretory phenotype by interfering with IKK/NF-κB activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2016.183

BRD4 Connects Enhancer Remodeling to Senescence Immune Surveillance

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2016.183

Therapy-induced senescence in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2016.183

Role of cellular senescence in hepatic wound healing and carcinogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2016.183

Matricellular protein CCN1 promotes regression of liver fibrosis through induction of cellular senescence in hepatic myofibroblasts.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2016.183

Treating cancer with selective CDK4/6 inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2016.183

Clinical Development of the CDK4/6 Inhibitors Ribociclib and Abemaciclib in Breast Cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2016.183

CDK4/6 inhibition induces epithelial cell cycle arrest and ameliorates acute kidney injury.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2016.183

Specific lipofuscin staining as a novel biomarker to detect replicative and stress-induced senescence. A method applicable in cryo-preserved and archival tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2016.183

Living on a break: cellular senescence as a DNA-damage response

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2016.183

Detection of senescence-associated heterochromatin foci (SAHF).

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2016.183

Senescence and quiescence induced compromised function in cultured macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2016.183

The limitations and validities of senescence associated-beta-galactosidase activity as an aging marker for human foreskin fibroblast Hs68 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2016.183

The tumor suppressor ARF regulates innate immune responses in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2016.183

Real-time in vivo imaging of p16gene expression: a new approach to study senescence stress signaling in living animals

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2016.183

WAF1, a potential mediator of p53 tumor suppression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2016.183

The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2016.183

Cellular senescence and tumor suppressor gene p16

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2016.183

The signals and pathways activating cellular senescence

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2016.183

p21 and mTERT are novel markers for determining different ischemic time periods in renal ischemia-reperfusion injury.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2016.183

PLEIOTROPY, NATURAL SELECTION, AND THE EVOLUTION OF SENESCENCE

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2016.183

Positive effect of the induction of p21WAF1/CIP1 on the course of ischemic acute renal failure

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2016.183

Increased expression of senescence-associated cell cycle inhibitor p16INK4a in deteriorating renal transplants and diseased native kidney

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2016.183

Activation of a promyelocytic leukemia-tumor protein 53 axis underlies acute promyelocytic leukemia cure

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2016.183

The parameters of the ageing kidney

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2016.183

Increased expression of p16(INK4a) and p27(Kip1) cyclin-dependent kinase inhibitor genes in aging human kidney and chronic allograft nephropathy

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2016.183

Accelerated expression of senescence associated cell cycle inhibitor p16INK4A in kidneys with glomerular disease

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2016.183

A crucial role for adipose tissue p53 in the regulation of insulin resistance

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2016.183

The cyclin kinase inhibitor p21WAF1/CIP1 is required for glomerular hypertrophy in experimental diabetic nephropathy

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2016.183

Premature senescence of skin fibroblasts from insulin-dependent diabetic patients with kidney disease

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2016.183

Kidney disease and aging: A reciprocal relation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2016.183

Synthesis of a poly(vinylpyrrolidone-co-dimethyl maleic anhydride) co-polymer and its application for renal drug targeting

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2016.183

Angiotensin II induces premature senescence of vascular smooth muscle cells and accelerates the development of atherosclerosis via a p21-dependent pathway

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2016.183

Caloric restriction and genomic stability

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2016.183

Inorganic Phosphate Activates the AKT/mTORC1 Pathway and Shortens the Life Span of an α‑Klotho-Deficient Model

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2016.183

A role for AMP-activated protein kinase in diabetes-induced renal hypertrophy

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEPH.2016.183

The combination of donor and recipient age is critical in determining host immunoresponsiveness and renal transplant outcome

31 March 2020

1 reference

12 December 2020

Senescence-associated (beta)-galactosidase reflects an increase in lysosomal mass during replicative ageing of human endothelial cells

1 reference

12 December 2020

Proliferative activity of cyst epithelium in human renal cystic diseases

1 reference

12 December 2020

Beta-galactosidase staining on bone marrow. The osteoclast pitfall

1 reference

12 December 2020

Acute kidney injury: a guide to diagnosis and management.

1 reference

12 December 2020

Functional changes in the aging kidney.

1 reference

12 December 2020

Reciprocal Rb inactivation and p16INK4 expression in primary lung cancers and cell lines.

1 reference

12 December 2020

Replicative senescence in kidney aging, renal disease, and renal transplantation.

1 reference

12 December 2020

Lymphocyte subsets and natural killer cell activity in healthy old people and centenarians.

1 reference

12 December 2020

Low-molecular-weight proteins as carriers for renal drug targeting.

1 reference

12 December 2020