(Q40516595)

English

Effects of a conditionally active v-ErbB and an EGF-R inhibitor on transformation of NIH-3T3 cells and abrogation of cytokine dependency of hematopoietic cells

scientific article published on October 2004

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scholarly article

1 reference

Europe PubMed Central

21 September 2017

Effects of a conditionally active v-ErbB and an EGF-R inhibitor on transformation of NIH-3T3 cells and abrogation of cytokine dependency of hematopoietic cells (English)

1 reference

Europe PubMed Central

21 September 2017

author name string

James A McCubrey

1

1 reference

Europe PubMed Central

21 September 2017

John G Shelton

2

1 reference

Europe PubMed Central

21 September 2017

Linda S Steelman

3

1 reference

Europe PubMed Central

21 September 2017

Richard A Franklin

4

1 reference

Europe PubMed Central

21 September 2017

Thazepadath Sreevalsan

5

1 reference

Europe PubMed Central

21 September 2017

Martin McMahon

6

1 reference

Europe PubMed Central

21 September 2017

language of work or name

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publication date

1 October 2004

1 reference

Europe PubMed Central

21 September 2017

1 reference

Europe PubMed Central

21 September 2017

23

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Europe PubMed Central

21 September 2017

47

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Europe PubMed Central

21 September 2017

7810-7820

1 reference

Europe PubMed Central

21 September 2017

https://scigraph.springernature.com/pub.10.1038/sj.onc.1208055

0 references

Pharmacologic inhibitors of MKK1 and MKK2.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208055

21 January 2018

Combined effects of aberrant MEK1 activity and BCL2 overexpression on relieving the cytokine dependency of human and murine hematopoietic cells.

1 reference

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21 January 2018

Effects of inducible MEK1 activation on the cytokine dependency of lymphoid cells

1 reference

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21 January 2018

A conditionally-active form of MEK1 results in autocrine tranformation of human and mouse hematopoietic cells.

1 reference

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21 January 2018

Requirement for the PI3K/Akt pathway in MEK1-mediated growth and prevention of apoptosis: identification of an Achilles heel in leukemia.

1 reference

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21 January 2018

Signal transduction, cell cycle regulatory, and anti-apoptotic pathways regulated by IL-3 in hematopoietic cells: possible sites for intervention with anti-neoplastic drugs

1 reference

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21 January 2018

Mutations of critical amino acids affect the biological and biochemical properties of oncogenic A-Raf and Raf-1.

1 reference

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21 January 2018

Involvement of PI3K/Akt pathway in cell cycle progression, apoptosis, and neoplastic transformation: a target for cancer chemotherapy.

1 reference

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21 January 2018

Signal transduction mediated by the Ras/Raf/MEK/ERK pathway from cytokine receptors to transcription factors: potential targeting for therapeutic intervention.

1 reference

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21 January 2018

Expression of a distinctive BCR-ABL oncogene in Ph1-positive acute lymphocytic leukemia (ALL).

1 reference

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21 January 2018

Growth of factor-dependent hemopoietic precursor cell lines

1 reference

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21 January 2018

Chemical genetic blockade of transformation reveals dependence on aberrant oncogenic signaling

1 reference

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21 January 2018

Identification of a novel inhibitor of mitogen-activated protein kinase kinase

1 reference

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21 January 2018

Differential abilities of the Raf family of protein kinases to abrogate cytokine dependency and prevent apoptosis in murine hematopoietic cells by a MEK1-dependent mechanism

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208055

21 January 2018

Signaling through the hematopoietic cytokine receptors.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208055

21 January 2018

Expression cloning of the human IL-3 receptor cDNA reveals a shared beta subunit for the human IL-3 and GM-CSF receptors

1 reference

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21 January 2018

Establishment and characterization of a unique human cell line that proliferates dependently on GM-CSF, IL-3, or erythropoietin

1 reference

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21 January 2018

EGFRvIII as a promising target for antibody-based brain tumor therapy

1 reference

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21 January 2018

Treatment by design in leukemia, a meeting report, Philadelphia, Pennsylvania, December 2002.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208055

21 January 2018

The Raf/MEK/ERK signal transduction cascade as a target for chemotherapeutic intervention in leukemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208055

21 January 2018

Oligomerization activates c-Raf-1 through a Ras-dependent mechanism

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208055

21 January 2018

Serine/threonine phosphorylation in cytokine signal transduction

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208055

21 January 2018

Differential abilities of activated Raf oncoproteins to abrogate cytokine dependency, prevent apoptosis and induce autocrine growth factor synthesis in human hematopoietic cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208055

21 January 2018

Enrichment of hematopoietic precursor cells and cloning of multipotential B-lymphocyte precursors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208055

21 January 2018

Steroid receptor fusion proteins for conditional activation of Raf-MEK-ERK signaling pathway

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208055

21 January 2018

The amino-terminal 14 amino acids of v-src can functionally replace the extracellular and transmembrane domains of v-erbB

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208055

21 January 2018

Controlled dimerization of ErbB receptors provides evidence for differential signaling by homo- and heterodimers

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208055

21 January 2018

Conditionally oncogenic forms of the A-Raf and B-Raf protein kinases display different biological and biochemical properties in NIH 3T3 cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208055

21 January 2018

Conditional transformation of cells and rapid activation of the mitogen-activated protein kinase cascade by an estradiol-dependent human raf-1 protein kinase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208055

21 January 2018

Effects of the RAF/MEK/ERK and PI3K/AKT signal transduction pathways on the abrogation of cytokine-dependence and prevention of apoptosis in hematopoietic cells.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208055

21 January 2018

JAK/STAT, Raf/MEK/ERK, PI3K/Akt and BCR-ABL in cell cycle progression and leukemogenesis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208055

21 January 2018

Leukemic transformation of normal murine erythroid progenitors: v- and c-ErbB act through signaling pathways activated by the EpoR and c-Kit in stress erythropoiesis

1 reference

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21 January 2018

Chimaeras of Myc oncoprotein and steroid receptors cause hormone-dependent transformation of cells

1 reference

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21 January 2018

Activation of the Raf-1 kinase cascade by coumermycin-induced dimerization.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208055

7 January 2021

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10.1038/SJ.ONC.1208055

1 reference

Europe PubMed Central

21 September 2017

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1 reference

Europe PubMed Central

21 September 2017

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