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BAX channel activity mediates lysosomal disruption linked to Parkinson disease.
scientific article published on 26 March 2014
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Europe PubMed Central
PMC publication ID
5119069
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24686337%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 March 2020
title
BAX channel activity mediates lysosomal disruption linked to Parkinson disease
(English)
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Europe PubMed Central
PMC publication ID
5119069
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24686337%20AND%20SRC:MED&resulttype=core&format=json
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12 March 2020
main subject
Parkinson's disease
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author
Miquel Vila
series ordinal
8
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Europe PubMed Central
PMC publication ID
5119069
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24686337%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 March 2020
Marta Martinez-vicente
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2
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Europe PubMed Central
PMC publication ID
5119069
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24686337%20AND%20SRC:MED&resulttype=core&format=json
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12 March 2020
Benjamin Dehay
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3
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PMC publication ID
5119069
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24686337%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 March 2020
Ariadna Recasens
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5
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PMC publication ID
5119069
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24686337%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 March 2020
author name string
Jordi Bové
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1
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PMC publication ID
5119069
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24686337%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 March 2020
Celine Perier
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4
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Europe PubMed Central
PMC publication ID
5119069
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24686337%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 March 2020
Agnes Bombrun
series ordinal
6
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PMC publication ID
5119069
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24686337%20AND%20SRC:MED&resulttype=core&format=json
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12 March 2020
Bruno Antonsson
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7
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5119069
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24686337%20AND%20SRC:MED&resulttype=core&format=json
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12 March 2020
publication date
26 March 2014
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PMC publication ID
5119069
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24686337%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 March 2020
published in
Autophagy
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Europe PubMed Central
PMC publication ID
5119069
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24686337%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 March 2020
volume
10
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Europe PubMed Central
PMC publication ID
5119069
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24686337%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 March 2020
issue
5
1 reference
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Europe PubMed Central
PMC publication ID
5119069
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24686337%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 March 2020
page(s)
889-900
1 reference
stated in
Europe PubMed Central
PMC publication ID
5119069
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24686337%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 March 2020
describes a project that uses
ImageJ
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Europe PubMed Central
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11 June 2022
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/PMC5119069/fullTextXML
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TFEB-mediated autophagy rescues midbrain dopamine neurons from α-synuclein toxicity
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Loss of P-type ATPase ATP13A2/PARK9 function induces general lysosomal deficiency and leads to Parkinson disease neurodegeneration.
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29 May 2018
Deficiency of ATP13A2 leads to lysosomal dysfunction, α-synuclein accumulation, and neurotoxicity
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Pathogenic lysosomal depletion in Parkinson's disease
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29 May 2018
Tumor necrosis factor-related apoptosis-inducing ligand activates a lysosomal pathway of apoptosis that is regulated by Bcl-2 proteins
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29 May 2018
Two molecular pathways initiate mitochondria-dependent dopaminergic neurodegeneration in experimental Parkinson's disease
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29 May 2018
Bax inhibition protects against free fatty acid-induced lysosomal permeabilization
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Complex I deficiency primes Bax-dependent neuronal apoptosis through mitochondrial oxidative damage
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Bax channel inhibitors prevent mitochondrion-mediated apoptosis and protect neurons in a model of global brain ischemia.
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Lysosomal membrane permeabilization during apoptosis--involvement of Bax?
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Lysosomal destabilization in p53-induced apoptosis
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Caspase-9 activation results in downstream caspase-8 activation and bid cleavage in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced Parkinson's disease
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Bax ablation prevents dopaminergic neurodegeneration in the 1-methyl- 4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson's disease
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Caspase-3: A vulnerability factor and final effector in apoptotic death of dopaminergic neurons in Parkinson's disease.
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Transgenic mice expressing human Bcl-2 in their neurons are resistant to 6-hydroxydopamine and 1-methyl-4-phenyl-1,2,3,6- tetrahydropyridine neurotoxicity
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A population of rat liver lysosomes responsible for the selective uptake and degradation of cytosolic proteins
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29 May 2018
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17 August 2018
Apoptosis-inducing factor deficiency sensitizes dopaminergic neurons to parkinsonian neurotoxins
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17 August 2018
Lysosomal membrane permeabilization and cathepsin release is a Bax/Bak-dependent, amplifying event of apoptosis in fibroblasts and monocytes.
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17 August 2018
Alterations in lysosomal and proteasomal markers in Parkinson's disease: relationship to alpha-synuclein inclusions.
1 reference
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17 August 2018
Membrane-permeable Bcl-xL prevents MPTP-induced dopaminergic neuronal loss in the substantia nigra.
1 reference
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5119069
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17 August 2018
Tumor necrosis factor-alpha-associated lysosomal permeabilization is cathepsin B dependent
1 reference
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5119069
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17 August 2018
Parkinson-like neurodegeneration induced by targeted overexpression of alpha-synuclein in the nigrostriatal system.
1 reference
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5119069
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17 August 2018
Is Bax a mitochondrial mediator in apoptotic death of dopaminergic neurons in Parkinson's disease?
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5119069
retrieved
17 August 2018
1-Methyl-4-phenyl-1,2,3,6-tetrahydropyride neurotoxicity is attenuated in mice overexpressing Bcl-2.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5119069
retrieved
17 August 2018
Lysosomal membrane permeabilization in Parkinson disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.4161%2FAUTO.28286
retrieved
21 January 2018
Identifiers
DOI
10.4161/AUTO.28286
1 reference
stated in
Europe PubMed Central
PMC publication ID
5119069
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24686337%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 March 2020
PMC publication ID
5119069
1 reference
stated in
Europe PubMed Central
PMC publication ID
5119069
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24686337%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 March 2020
PubMed publication ID
24686337
1 reference
stated in
Europe PubMed Central
PMC publication ID
5119069
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24686337%20AND%20SRC:MED&resulttype=core&format=json
retrieved
12 March 2020
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