(Q48858900)

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Neuroprotective Effect of Fisetin Against Amyloid-Beta-Induced Cognitive/Synaptic Dysfunction, Neuroinflammation, and Neurodegeneration in Adult Mice.

scientific article published on 5 March 2016

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9 March 2020

Neuroprotective Effect of Fisetin Against Amyloid-Beta-Induced Cognitive/Synaptic Dysfunction, Neuroinflammation, and Neurodegeneration in Adult Mice (English)

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9 March 2020

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9 March 2020

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Ashfaq Ahmad

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9 March 2020

Hyun Young Park

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9 March 2020

Haroon Badshah

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9 March 2020

Shafiq Ur Rehman

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9 March 2020

Myeong Ok Kim

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9 March 2020

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5 March 2016

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9 March 2020

Molecular Neurobiology

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9 March 2020

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9 March 2020

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9 March 2020

2269-2285

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9 March 2020

https://scigraph.springernature.com/pub.10.1007/s12035-016-9795-4

0 references

Amyloid cascade hypothesis: Pathogenesis and therapeutic strategies in Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-9795-4

21 January 2018

Schisantherin A recovers Aβ-induced neurodegeneration with cognitive decline in mice.

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-9795-4

21 January 2018

Esculentoside A suppresses Aβ(1-42)-induced neuroinflammation by down-regulating MAPKs pathways in vivo.

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-9795-4

21 January 2018

Aβ42 oligomers selectively disrupt neuronal calcium release.

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-9795-4

21 January 2018

Synaptic changes in Alzheimer's disease and its models

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-9795-4

21 January 2018

Tau pathogenesis is promoted by Aβ1-42 but not Aβ1-40.

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-9795-4

21 January 2018

Amyloid-β Impairs Synaptic Inhibition via GABA(A) Receptor Endocytosis.

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-9795-4

21 January 2018

Amyloid β oligomers in Alzheimer's disease pathogenesis, treatment, and diagnosis

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-9795-4

21 January 2018

Protection of TGF-β1 against neuroinflammation and neurodegeneration in Aβ1-42-induced Alzheimer's disease model rats

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-9795-4

21 January 2018

Neuroinflammation: implications for the pathogenesis and molecular diagnosis of Alzheimer's disease

1 reference

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21 January 2018

Curcumin inhibits Aβ-induced microglial inflammatory responses in vitro: Involvement of ERK1/2 and p38 signaling pathways

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-9795-4

21 January 2018

Alzheimer mechanisms and therapeutic strategies

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-9795-4

21 January 2018

Fisetin: a dietary antioxidant for health promotion

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-9795-4

21 January 2018

Modulation of p25 and inflammatory pathways by fisetin maintains cognitive function in Alzheimer's disease transgenic mice

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-9795-4

21 January 2018

Antioxidant activity, cellular bioavailability, and iron and calcium management of neuroprotective and nonneuroprotective flavones

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-9795-4

21 January 2018

Structural requirements for the flavonoid fisetin in inhibiting fibril formation of amyloid beta protein

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-9795-4

21 January 2018

Fisetin enhances behavioral performances and attenuates reactive gliosis and inflammation during aluminum chloride-induced neurotoxicity.

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-9795-4

21 January 2018

Dietary flavonoid fisetin regulates aluminium chloride-induced neuronal apoptosis in cortex and hippocampus of mice brain.

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-9795-4

21 January 2018

ERK activation by the polyphenols fisetin and resveratrol provides neuroprotection in multiple models of Huntington's disease

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-9795-4

21 January 2018

Modulation of multiple pathways involved in the maintenance of neuronal function during aging by fisetin

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-9795-4

21 January 2018

Fisetin lowers methylglyoxal dependent protein glycation and limits the complications of diabetes

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-9795-4

21 January 2018

Fisetin alleviates early brain injury following experimental subarachnoid hemorrhage in rats possibly by suppressing TLR 4/NF-κB signaling pathway

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-9795-4

21 January 2018

Hypothermia-induced hyperphosphorylation: a new model to study tau kinase inhibitors

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-9795-4

21 January 2018

Melatonin attenuates D-galactose-induced memory impairment, neuroinflammation and neurodegeneration via RAGE/NF-K B/JNK signaling pathway in aging mouse model

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-9795-4

21 January 2018

Melatonin ameliorates amyloid beta-induced memory deficits, tau hyperphosphorylation and neurodegeneration via PI3/Akt/GSk3β pathway in the mouse hippocampus.

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-9795-4

21 January 2018

Protective Effect of Lupeol Against Lipopolysaccharide-Induced Neuroinflammation via the p38/c-Jun N-Terminal Kinase Pathway in the Adult Mouse Brain.

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-9795-4

21 January 2018

Protection of the developing brain with anthocyanins against ethanol-induced oxidative stress and neurodegeneration

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-9795-4

21 January 2018

Amyloid beta peptide 1-42 disturbs intracellular calcium homeostasis through activation of GluN2B-containing N-methyl-d-aspartate receptors in cortical cultures.

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-9795-4

21 January 2018

Soluble oligomers of amyloid-β peptide disrupt membrane trafficking of α-amino-3-hydroxy-5-methylisoxazole-4-propionic acid receptor contributing to early synapse dysfunction.

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-9795-4

21 January 2018

Inhibition of Wnt and PI3K signaling modulates GSK-3beta activity and induces morphological changes in cortical neurons: role of tau phosphorylation.

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-9795-4

21 January 2018

Osmotin attenuates amyloid beta-induced memory impairment, tau phosphorylation and neurodegeneration in the mouse hippocampus

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-9795-4

21 January 2018

Inflammation in neurodegenerative disease--a double-edged sword

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-9795-4

21 January 2018

Inflammation and Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-9795-4

21 January 2018

The essential role of p53-up-regulated modulator of apoptosis (Puma) and its regulation by FoxO3a transcription factor in β-amyloid-induced neuron death

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-9795-4

21 January 2018

Hyperphosphorylation of Tau induced by naturally secreted amyloid-β at nanomolar concentrations is modulated by insulin-dependent Akt-GSK3β signaling pathway

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-9795-4

21 January 2018

Neurotoxicity and memory deficits induced by soluble low-molecular-weight amyloid-β1-42 oligomers are revealed in vivo by using a novel animal model.

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-9795-4

21 January 2018

beta-Amyloid infusion results in delayed and age-dependent learning deficits without role of inflammation or beta-amyloid deposits.

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-9795-4

21 January 2018

Soluble protein oligomers in neurodegeneration: lessons from the Alzheimer's amyloid beta-peptide

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-9795-4

21 January 2018

Schisandrin C Ameliorates Learning and Memory Deficits by Aβ1-42 -induced Oxidative Stress and Neurotoxicity in Mice.

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-9795-4

21 January 2018

AMPAR removal underlies Abeta-induced synaptic depression and dendritic spine loss

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-9795-4

21 January 2018

Adenosine A2A receptor blockade prevents synaptotoxicity and memory dysfunction caused by beta-amyloid peptides via p38 mitogen-activated protein kinase pathway

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-9795-4

21 January 2018

Postsynaptic density 95 controls AMPA receptor incorporation during long-term potentiation and experience-driven synaptic plasticity.

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-9795-4

21 January 2018

CREB phosphorylation as a molecular marker of memory processing in the hippocampus for spatial learning

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-9795-4

21 January 2018

Genetic approaches to investigate the role of CREB in neuronal plasticity and memory.

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-9795-4

21 January 2018

Pratensein attenuates Aβ-induced cognitive deficits in rats: enhancement of synaptic plasticity and cholinergic function

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-9795-4

21 January 2018

Cognitive-enhancing effects of Rhus verniciflua bark extract and its active flavonoids with neuroprotective and anti-inflammatory activities

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-9795-4

21 January 2018

CREB is necessary for synaptic maintenance and learning-induced changes of the AMPA receptor GluA1 subunit

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-9795-4

21 January 2018

Age-dependent accumulation of soluble amyloid beta (Abeta) oligomers reverses the neuroprotective effect of soluble amyloid precursor protein-alpha (sAPP(alpha)) by modulating phosphatidylinositol 3-kinase (PI3K)/Akt-GSK-3beta pathway in Alzheimer m

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-9795-4

21 January 2018

Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-9795-4

21 January 2018

Essential role for protein kinase B (PKB) in insulin-induced glycogen synthase kinase 3 inactivation. Characterization of dominant-negative mutant of PKB.

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-9795-4

21 January 2018

Amyloid-beta-induced neurotoxicity is reduced by inhibition of glycogen synthase kinase-3.

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-9795-4

21 January 2018

FLZ alleviates the memory deficits in transgenic mouse model of Alzheimer's disease via decreasing beta-amyloid production and tau hyperphosphorylation

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-9795-4

21 January 2018

Truncation and activation of GSK-3β by calpain I: a molecular mechanism links to tau hyperphosphorylation in Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-9795-4

21 January 2018

Chronic lithium administration to FTDP-17 tau and GSK-3beta overexpressing mice prevents tau hyperphosphorylation and neurofibrillary tangle formation, but pre-formed neurofibrillary tangles do not revert.

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-9795-4

21 January 2018

Suppression of nuclear factor kappa B ameliorates astrogliosis but not amyloid burden in APPswe/PS1dE9 mice

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-9795-4

21 January 2018

Inflammation in Alzheimer disease-a brief review of the basic science and clinical literature

1 reference

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21 January 2018

Extracellular deposition of beta-amyloid upon p53-dependent neuronal cell death in transgenic mice

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-9795-4

21 January 2018

The regulation of p53 up-regulated modulator of apoptosis by JNK/c-Jun pathway in β-amyloid-induced neuron death.

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-9795-4

21 January 2018

Neuroglobin Attenuates Beta Amyloid-Induced Apoptosis Through Inhibiting Caspases Activity by Activating PI3K/Akt Signaling Pathway

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-9795-4

21 January 2018

Poly(ADP-ribose) polymerase-1 in amyloid beta toxicity and Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-9795-4

21 January 2018

Flavonoids and brain health: multiple effects underpinned by common mechanisms

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-9795-4

21 January 2018

Effect of flavonoids on learning, memory and neurocognitive performance: relevance and potential implications for Alzheimer's disease pathophysiology.

1 reference

https://api.crossref.org/works/10.1007%2FS12035-016-9795-4

21 January 2018

Animal models of Alzheimer's disease: therapeutic implications.

1 reference

https://pubmed.ncbi.nlm.nih.gov/26944285

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Amyloid-β1-42 Disrupts Synaptic Plasticity by Altering Glutamate Recycling at the Synapse.

1 reference

https://pubmed.ncbi.nlm.nih.gov/26944285

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of amyloid beta peptide on poly(ADP-ribose) polymerase activity in adult and aged rat hippocampus.

1 reference

https://pubmed.ncbi.nlm.nih.gov/26944285

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Anthocyanins Reversed D-Galactose-Induced Oxidative Stress and Neuroinflammation Mediated Cognitive Impairment in Adult Rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/26944285

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Biochemical stages of amyloid-β peptide aggregation and accumulation in the human brain and their association with symptomatic and pathologically preclinical Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/26944285

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protective effects of anthocyanins against amyloid beta-induced neurotoxicity in vivo and in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/26944285

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S12035-016-9795-4

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26944285%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26944285%20AND%20SRC:MED&resulttype=core&format=json

9 March 2020

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