(Q49136975)

18 February 2018

title

Stress kinases involved in tau phosphorylation in Alzheimer's disease, tauopathies and APP transgenic mice. (English)

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18 February 2018

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I Ferrer

1

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18 February 2018

publication date

1 January 2004

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18 February 2018

published in

Neurotoxicity Research

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18 February 2018

volume

6

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18 February 2018

issue

6

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18 February 2018

page(s)

469-475

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18 February 2018

https://scigraph.springernature.com/pub.10.1007/bf03033283

exact match

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cites work

Activation of the JNK/p38 pathway occurs in diseases characterized by tau protein pathology and is related to tau phosphorylation but not to apoptosis.

1 reference

https://api.crossref.org/works/10.1007%2FBF03033283

Tau gene mutations: dissecting the pathogenesis of FTDP-17.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03033283

Neurofibrillary pathology in transgenic mice overexpressing V717F beta-amyloid precursor protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03033283

Oxidative damage is the earliest event in Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03033283

Argyrophilic grain disease is a sporadic 4-repeat tauopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03033283

Effect of the lipid peroxidation product acrolein on tau phosphorylation in neural cells

21 January 2018

1 reference

12 December 2020

p38 kinase is activated in the Alzheimer's disease brain.

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12 December 2020

Oxidative stress and neuronal adaptation in Alzheimer disease: the role of SAPK pathways

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12 December 2020

The p38 pathway is activated in Pick disease and progressive supranuclear palsy: a mechanistic link between mitogenic pathways, oxidative stress, and tau.

1 reference

12 December 2020

Tau protein pathology in neurodegenerative diseases.

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12 December 2020

A role for c-Jun N-terminal kinase 1 (JNK1), but not JNK2, in the beta-amyloid-mediated stabilization of protein p53 and induction of the apoptotic cascade in cultured cortical neurons

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12 December 2020

Differential activation of neuronal ERK, JNK/SAPK and p38 in Alzheimer disease: the 'two hit' hypothesis.

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12 December 2020

Alzheimer-type neuropathology in transgenic mice overexpressing V717F β-amyloid precursor protein

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12 December 2020

Correlative Memory Deficits, Abeta Elevation, and Amyloid Plaques in Transgenic Mice

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12 December 2020

Active stress kinase p38 enhances and perpetuates abnormal tau phosphorylation and deposition in Pick's disease

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12 December 2020

Brain Abeta amyloidosis in APPsw mice induces accumulation of presenilin-1 and tau.

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12 December 2020

P38 MAP kinase is activated at early stages in Alzheimer's disease brain.

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12 December 2020

Phosphorylated mitogen-activated protein kinase (MAPK/ERK-P), protein kinase of 38 kDa (p38-P), stress-activated protein kinase (SAPK/JNK-P), and calcium/calmodulin-dependent kinase II (CaM kinase II) are differentially expressed in tau deposits in

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12 December 2020

Accelerated Alzheimer-type phenotype in transgenic mice carrying both mutant amyloid precursor protein and presenilin 1 transgenes

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12 December 2020

Localization of superoxide dismutases in Alzheimer's disease and Down's syndrome neocortex and hippocampus

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12 December 2020

Total inactivation of gamma-secretase activity in presenilin-deficient embryonic stem cells.

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12 December 2020

Activation of p38 kinase links tau phosphorylation, oxidative stress, and cell cycle-related events in Alzheimer disease

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12 December 2020

CEP-1347/KT-7515, an inhibitor of SAPK/JNK pathway activation, promotes survival and blocks multiple events associated with Abeta-induced cortical neuron apoptosis

1 reference

12 December 2020

Abeta deposition is associated with neuropil changes, but not with overt neuronal loss in the human amyloid precursor protein V717F (PDAPP) transgenic mouse.

1 reference

12 December 2020

Phosphorylated map kinase (ERK1, ERK2) expression is associated with early tau deposition in neurones and glial cells, but not with increased nuclear DNA vulnerability and cell death, in Alzheimer disease, Pick's disease, progressive supranuclear pa

1 reference

12 December 2020

Oxidative stress in Alzheimer's disease

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12 December 2020

Expression of stress-activated kinases c-Jun N-terminal kinase (SAPK/JNK-P) and p38 kinase (p38-P), and tau hyperphosphorylation in neurites surrounding betaA plaques in APP Tg2576 mice

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12 December 2020

Time sequence of maturation of dystrophic neurites associated with Abeta deposits in APP/PS1 transgenic mice

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12 December 2020

Phosphorylation of microtubule-associated protein tau by stress-activated protein kinases in intact cells

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12 December 2020

Phosphorylated c-MYC expression in Alzheimer disease, Pick's disease, progressive supranuclear palsy and corticobasal degeneration.

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12 December 2020

A role for 4-hydroxynonenal, an aldehydic product of lipid peroxidation, in disruption of ion homeostasis and neuronal death induced by amyloid beta-peptide.

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12 December 2020

Reactivating kinase/p38 phosphorylates tau protein in vitro.

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12 December 2020

Oxidative alterations in Alzheimer's disease.

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12 December 2020

Phosphorylated protein kinases associated with neuronal and glial tau deposits in argyrophilic grain disease.

1 reference

12 December 2020

Signaling events in amyloid beta-peptide-induced neuronal death and insulin-like growth factor I protection

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12 December 2020

Early AGEing and Alzheimer's.

1 reference

12 December 2020

Localization of active forms of C-jun kinase (JNK) and p38 kinase in Alzheimer's disease brains at different stages of neurofibrillary degeneration.

1 reference

12 December 2020

Beta-amyloid induces neuronal apoptosis via a mechanism that involves the c-Jun N-terminal kinase pathway and the induction of Fas ligand.

1 reference

12 December 2020

The role of the MAP-kinase superfamily in beta-amyloid toxicity

1 reference

12 December 2020

Alzheimer's disease and oxidative stress: implications for novel therapeutic approaches

1 reference

12 December 2020

H2O2 and 4-hydroxynonenal mediate amyloid beta-induced neuronal apoptosis by activating JNKs and p38MAPK.

1 reference

12 December 2020

Activation of c-Jun N-terminal kinase and p38 in an Alzheimer's disease model is associated with amyloid deposition.

1 reference

12 December 2020

Demonstration by fluorescence resonance energy transfer of a close association between activated MAP kinase and neurofibrillary tangles: implications for MAP kinase activation in Alzheimer disease.

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12 December 2020

RNA oxidation is a prominent feature of vulnerable neurons in Alzheimer's disease.

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12 December 2020

Tau protein isoforms, phosphorylation and role in neurodegenerative disorders11These authors contributed equally to this work

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12 December 2020

Evidence that 4-hydroxynonenal mediates oxidative stress-induced neuronal apoptosis.

1 reference

12 December 2020

Phosphorylation of microtubule-associated protein tau by stress-activated protein kinases

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12 December 2020

Abeta 17-42 in Alzheimer's disease activates JNK and caspase-8 leading to neuronal apoptosis

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12 December 2020

Ubiquitin-negative mini-pick-like bodies in the dentate gyrus in p301l tauopathy

1 reference

12 December 2020

In situ immunodetection of neuronal caspase-3 activation in Alzheimer disease.

1 reference

12 December 2020

APPSw transgenic mice develop age-related A beta deposits and neuropil abnormalities, but no neuronal loss in CA1.

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12 December 2020

The role of mitogen-activated protein kinase pathways in Alzheimer's disease

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12 December 2020

Distribution, levels, and activation of MEK1 in Alzheimer's disease

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12 December 2020

Stress-activated protein kinase/c-jun N-terminal kinase phosphorylates tau protein.

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12 December 2020

Presenilins are required for gamma-secretase cleavage of beta-APP and transmembrane cleavage of Notch-1

1 reference

12 December 2020

Tau phosphorylation and kinase activation in familial tauopathy linked to deln296 mutation.

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12 December 2020

Two amyloid precursor protein transgenic mouse models with Alzheimer disease-like pathology

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12 December 2020

Tau function and dysfunction in neurons: its role in neurodegenerative disorders

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12 December 2020

Modulation of tau phosphorylation and intracellular localization by cellular stress

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12 December 2020

The phosphorylation of tau: a critical stage in neurodevelopment and neurodegenerative processes.

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12 December 2020

Mysterious liaisons: the relationship between c-Myc and the cell cycle.

1 reference

12 December 2020

Lipoperoxidation is selectively involved in progressive supranuclear palsy

1 reference

12 December 2020

Evidence of oxidative stress and in vivo neurotoxicity of beta-amyloid in a transgenic mouse model of Alzheimer's disease: a chronic oxidative paradigm for testing antioxidant therapies in vivo

1 reference

12 December 2020

Immunohistochemical evidence of oxidative [corrected] stress in Alzheimer's disease

1 reference

12 December 2020

Neurodegenerative tauopathies

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12 December 2020

Amyloid-beta deposition in Alzheimer transgenic mice is associated with oxidative stress.

1 reference

12 December 2020

Neuropathology of human Alzheimer disease after immunization with amyloid-beta peptide: a case report.

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12 December 2020

JKK1, an upstream activator of JNK/SAPK, is activated in Alzheimer's disease.

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12 December 2020

Activation of MKK6, an upstream activator of p38, in Alzheimer's disease.

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12 December 2020

beta-Amyloid-induced neuronal apoptosis requires c-Jun N-terminal kinase activation.

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12 December 2020

Activation and redistribution of c-jun N-terminal kinase/stress activated protein kinase in degenerating neurons in Alzheimer's disease.

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12 December 2020

beta-Amyloid induces oxidative DNA damage and cell death through activation of c-Jun N terminal kinase

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12 December 2020

Phosphorylation sites on tau identified by nanoelectrospray mass spectrometry: differences in vitro between the mitogen-activated protein kinases ERK2, c-Jun N-terminal kinase and P38, and glycogen synthase kinase-3beta

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12 December 2020

Reactive Oxygen Species Mediate Cellular Damage in Alzheimer Disease.

1 reference

12 December 2020

Activation of neuronal extracellular receptor kinase (ERK) in Alzheimer disease links oxidative stress to abnormal phosphorylation.

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12 December 2020

Sites of phosphorylation in tau and factors affecting their regulation.

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12 December 2020

Neuropathology and pathogenesis of encephalitis following amyloid-beta immunization in Alzheimer's disease.

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12 December 2020

Accelerated amyloid deposition in the brains of transgenic mice coexpressing mutant presenilin 1 and amyloid precursor proteins.

1 reference

12 December 2020

Identifiers

DOI

10.1007/BF03033283

1 reference

18 February 2018

Dimensions Publication ID

0 references

1 reference

18 February 2018