(Q57664796)

1

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D. Scherer

2

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M. Drechsel

3

0 references

K. Hemminki

Actas Dermo-Sifiliográficas

4

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publication date

November 2009

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published in

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volume

100

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page(s)

38-51

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cites work

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Global perspectives of contemporary epidemiological trends of cutaneous malignant melanoma

7 January 2021

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Cutaneous melanoma in Caucasian New Zealanders: 1995-1999.

7 January 2021

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Incidence of and survival from malignant melanoma in Scotland: an epidemiological study

7 January 2021

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The epidemiology of skin cancer

7 January 2021

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Melanoma incidence trends

7 January 2021

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Time trends of cutaneous melanoma in Queensland, Australia and Central Europe

7 January 2021

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Incidence of malignant melanoma in Auckland, New Zealand: highest rates in the world.

7 January 2021

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Recent Trends in Cutaneous Melanoma Incidence Among Whites in the United States

7 January 2021

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Trends by anatomic site in the incidence of cutaneous malignant melanoma in Canada, 1969-93.

7 January 2021

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Epidemiology of cutaneous melanoma in Germany and worldwide

7 January 2021

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Trends in incidence of cutaneous malignant melanoma in a Swedish population 1976-1994.

7 January 2021

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Population-based study of cutaneous malignant melanoma in the Granada province (Spain), 1985-1992.

7 January 2021

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Clinicopathologic analysis of malignant melanoma in Taiwan

7 January 2021

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Basal cell carcinoma, squamous cell carcinoma and melanoma of the skin: analysis of the Singapore Cancer Registry data 1968-97.

7 January 2021

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Cutaneous melanoma in childhood and adolescence

7 January 2021

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Melanoma in children and adolescents

7 January 2021

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7 January 2021

Epidemiology of melanoma

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Cutaneous malignant melanoma in Europe.

7 January 2021

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Meta-analysis of risk factors for cutaneous melanoma: III. Family history, actinic damage and phenotypic factors

7 January 2021

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Melanoma and sun exposure: an overview of published studies

7 January 2021

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Risk of cutaneous melanoma associated with a family history of the disease

7 January 2021

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Neonatal sunburn and melanoma in mice

7 January 2021

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Influence of sun exposures during childhood and during adulthood on melanoma risk. EPIMEL and EORTC Melanoma Cooperative Group. European Organisation for Research and Treatment of Cancer

7 January 2021

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Clinically recognized dysplastic nevi. A central risk factor for cutaneous melanoma.

7 January 2021

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Acquired melanocytic nevi as risk factor for melanoma development. A comprehensive review of epidemiological data

7 January 2021

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Naevi and pigmentary characteristics as risk factors for melanoma in a high-risk population: a case-control study in New South Wales, Australia.

7 January 2021

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Estimation of genetic and environmental components in colorectal and lung cancer and melanoma

7 January 2021

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Environmental and heritable factors in the causation of cancer--analyses of cohorts of twins from Sweden, Denmark, and Finland

7 January 2021

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A population-based study of familial cutaneous melanoma

7 January 2021

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New developments in melanoma genetics

7 January 2021

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Genetics of melanoma predisposition

7 January 2021

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Germline mutations in the p16INK4a binding domain of CDK4 in familial melanoma

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0001-7310%2809%2973167-9

A large Norwegian family with inherited malignant melanoma, multiple atypical nevi, and CDK4 mutation

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0001-7310%2809%2973167-9

Prevalence of p16 and CDK4 germline mutations in 48 melanoma-prone families in France. The French Familial Melanoma Study Group [published erratum appears in Hum Mol Genet 1998 May;7(5):941]

7 January 2021

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https://api.crossref.org/works/10.1016%2FS0001-7310%2809%2973167-9

Role of the INK4a locus in tumor suppression and cell mortality.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0001-7310%2809%2973167-9

A cell cycle regulator potentially involved in genesis of many tumor types

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0001-7310%2809%2973167-9

Deletions of the cyclin-dependent kinase-4 inhibitor gene in multiple human cancers

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0001-7310%2809%2973167-9

Alternative reading frames of the INK4a tumor suppressor gene encode two unrelated proteins capable of inducing cell cycle arrest

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0001-7310%2809%2973167-9

Functional evidence for a role of combined CDKN2A (p16-p14(ARF))/CDKN2B (p15) gene inactivation in malignant gliomas.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0001-7310%2809%2973167-9

Mechanism of transcriptional repression of E2F by the retinoblastoma tumor suppressor protein.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0001-7310%2809%2973167-9

The Rb/E2F pathway: expanding roles and emerging paradigms

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0001-7310%2809%2973167-9

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0001-7310%2809%2973167-9

A new regulatory motif in cell-cycle control causing specific inhibition of cyclin D/CDK4

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0001-7310%2809%2973167-9

Sequential unfolding of ankyrin repeats in tumor suppressor p16

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0001-7310%2809%2973167-9

The Ink4a tumor suppressor gene product, p19Arf, interacts with MDM2 and neutralizes MDM2's inhibition of p53

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0001-7310%2809%2973167-9

ARF promotes MDM2 degradation and stabilizes p53: ARF-INK4a locus deletion impairs both the Rb and p53 tumor suppression pathways

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0001-7310%2809%2973167-9

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0001-7310%2809%2973167-9

Cooperative signals governing ARF-mdm2 interaction and nucleolar localization of the complex.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0001-7310%2809%2973167-9

Mutations in human ARF exon 2 disrupt its nucleolar localization and impair its ability to block nuclear export of MDM2 and p53

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0001-7310%2809%2973167-9

P19(ARF) stabilizes p53 by blocking nucleo-cytoplasmic shuttling of Mdm2

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0001-7310%2809%2973167-9

ARF function does not require p53 stabilization or Mdm2 relocalization

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0001-7310%2809%2973167-9

Stabilization of p53 by p14ARF without relocation of MDM2 to the nucleolus.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0001-7310%2809%2973167-9

Myc signaling via the ARF tumor suppressor regulates p53-dependent apoptosis and immortalization

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0001-7310%2809%2973167-9

Regulation of a senescence checkpoint response by the E2F1 transcription factor and p14(ARF) tumor suppressor

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0001-7310%2809%2973167-9

p14ARF links the tumour suppressors RB and p53.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0001-7310%2809%2973167-9

p19ARF links the tumour suppressor p53 to Ras

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0001-7310%2809%2973167-9

Loss of p16Ink4a with retention of p19Arf predisposes mice to tumorigenesis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0001-7310%2809%2973167-9

Biallelic mutations in p16(INK4a) confer resistance to Ras- and Ets-induced senescence in human diploid fibroblasts

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0001-7310%2809%2973167-9

Tumor suppression at the mouse INK4a locus mediated by the alternative reading frame product p19ARF

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0001-7310%2809%2973167-9

Expression of the p16INK4a tumor suppressor versus other INK4 family members during mouse development and aging.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0001-7310%2809%2973167-9

Role of p14(ARF) in replicative and induced senescence of human fibroblasts

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0001-7310%2809%2973167-9

Inhibition of p63 transcriptional activity by p14ARF: functional and physical link between human ARF tumor suppressor and a member of the p53 family

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0001-7310%2809%2973167-9

The ARF tumor suppressor inhibits BCL6-mediated transcriptional repression

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0001-7310%2809%2973167-9

ARF directly binds DP1: interaction with DP1 coincides with the G1 arrest function of ARF.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0001-7310%2809%2973167-9

AP-1 dimers regulate transcription of the p14/p19ARF tumor suppressor gene.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0001-7310%2809%2973167-9

Localization of phosphorylated forms of Bcl-2 in mitosis: co-localization with Ki-67 and nucleolin in nuclear structures and on mitotic chromosomes.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0001-7310%2809%2973167-9

Tumor suppressor ARF degrades B23, a nucleolar protein involved in ribosome biogenesis and cell proliferation.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0001-7310%2809%2973167-9

Nucleolar Arf tumor suppressor inhibits ribosomal RNA processing

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0001-7310%2809%2973167-9

Role of the proto-oncogene Pokemon in cellular transformation and ARF repression

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0001-7310%2809%2973167-9

Senescence bypass screen identifies TBX2, which represses Cdkn2a (p19(ARF)) and is amplified in a subset of human breast cancers.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0001-7310%2809%2973167-9

Twist is a potential oncogene that inhibits apoptosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0001-7310%2809%2973167-9

Loss of p16Ink4a confers susceptibility to metastatic melanoma in mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0001-7310%2809%2973167-9

Cooperative effects of INK4a and ras in melanoma susceptibility in vivo

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0001-7310%2809%2973167-9

Expression and significance of p53, rb, p21/waf-1, p16/ink-4a, and PTEN tumor suppressors in canine melanoma

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0001-7310%2809%2973167-9

Inactivation of p53 and retinoblastoma family pathways in canine osteosarcoma cell lines

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0001-7310%2809%2973167-9

Aberrant methylation of p16(INK4a) is an early event in lung cancer and a potential biomarker for early diagnosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0001-7310%2809%2973167-9

The p16/Cdkn2a/Ink4a gene is frequently deleted in nitrosourea-induced rat glial tumors.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0001-7310%2809%2973167-9

A CDKN2-like polymorphism in Xiphophorus LG V is associated with UV-B-induced melanoma formation in platyfish-swordtail hybrids

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0001-7310%2809%2973167-9

Geographical variation in the penetrance of CDKN2A mutations for melanoma

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0001-7310%2809%2973167-9

Genetic and environmental factors in cutaneous malignant melanoma

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0001-7310%2809%2973167-9

Genotype-Phenotype Relationships in U.S. Melanoma-Prone Families With CDKN2A and CDK4 Mutations

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0001-7310%2809%2973167-9

Patients with both pancreatic adenocarcinoma and melanoma may harbor germline CDKN2A mutations

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0001-7310%2809%2973167-9

A germline deletion of p14(ARF) but not CDKN2A in a melanoma-neural system tumour syndrome family

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0001-7310%2809%2973167-9

Selective deletion of exon 1 beta of the p19ARF gene in metastatic melanoma cell lines.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0001-7310%2809%2973167-9

Prevalence of 9p21 deletions in UK melanoma families.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0001-7310%2809%2973167-9

CDKN2A germline splicing mutation affecting both p16ink4 and p14arf RNA processing in a melanoma/neurofibroma kindred

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0001-7310%2809%2973167-9

Germline mutation of ARF in a melanoma kindred

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0001-7310%2809%2973167-9

A melanoma-associated germline mutation in exon 1beta inactivates p14ARF.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0001-7310%2809%2973167-9

A mutation hotspot at the p14ARF splice site.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0001-7310%2809%2973167-9

Virtually 100% of melanoma cell lines harbor alterations at the DNA level within CDKN2A, CDKN2B, or one of their downstream targets

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0001-7310%2809%2973167-9

Mutations in the CDKN2A ( p16INK4a ) gene in microdissected sporadic primary melanomas

7 January 2021

2 references

https://api.crossref.org/works/10.1016%2FS0001-7310%2809%2973167-9

7 January 2021

https://api.crossref.org/works/10.1016%2FS0001-7310%2809%2973167-9

inferred from DOI database lookup

7 January 2021

based on heuristic

p16INK4a inactivation is not frequent in uncultured sporadic primary cutaneous melanoma

1 reference

https://api.crossref.org/works/10.1016%2FS0001-7310%2809%2973167-9

The CDKN2A tumour suppressor gene: no mutations detected in patients with melanoma and additional unrelated cancers

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0001-7310%2809%2973167-9

p16(MTS-1/CDKN2/INK4a) in cancer progression

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0001-7310%2809%2973167-9

Analysis of the tumor suppressor gene p16(INK4A) in microdissected melanoma metastases by sequencing, and microsatellite and methylation screening

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0001-7310%2809%2973167-9

Loss of heterozygosity at chromosome 9p21 (INK4-p14ARF locus): homozygous deletions and mutations in the p16 and p14ARF genes in sporadic primary melanomas

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0001-7310%2809%2973167-9

Increased frequency of LOH on chromosome 9 in sporadic primary melanomas is associated with increased patient age at diagnosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0001-7310%2809%2973167-9

Loss of p16 expression is associated with histological features of melanoma invasion

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0001-7310%2809%2973167-9

CDKN2A Variants in a Population-Based Sample of Queensland Families With Melanoma

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0001-7310%2809%2973167-9

A single nucleotide polymorphism in the 3?untranslated region of theCDKN2A gene is common in sporadic primary melanomas but mutations in theCDKN2B,CDKN2C,CDK4 andp53 genes are rare

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0001-7310%2809%2973167-9

Informative MspI polymorphism adjacent to exon 3 of the p16INK4 (MTS1) gene

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0001-7310%2809%2973167-9

Analysis of G1/S checkpoint regulators in metastatic melanoma

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0001-7310%2809%2973167-9

Significant impact of promoter hypermethylation and the 540 C>T polymorphism of CDKN2A in cutaneous melanoma of the vertical growth phase

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0001-7310%2809%2973167-9

Cancer-associated mis-sense and deletion mutations impair p16INK4 CDK inhibitory activity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0001-7310%2809%2973167-9

Role of the CDKN2A locus in patients with multiple primary melanomas

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0001-7310%2809%2973167-9

Loss of Cdk4 expression causes insulin-deficient diabetes and Cdk4 activation results in beta-islet cell hyperplasia

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0001-7310%2809%2973167-9

Invasive melanoma in Cdk4-targeted mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0001-7310%2809%2973167-9

Melanocyte biology and skin pigmentation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0001-7310%2809%2973167-9

MC1R genotype modifies risk of melanoma in families segregating CDKN2A mutations

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0001-7310%2809%2973167-9

Melanocortin-1 receptor variant R151C modifies melanoma risk in Dutch families with melanoma.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0001-7310%2809%2973167-9

MC1R variants increase risk of melanomas harboring BRAF mutations.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0001-7310%2809%2973167-9

MC1R variants associated susceptibility to basal cell carcinoma of skin: interaction with host factors and XRCC3 polymorphism

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0001-7310%2809%2973167-9

Melanocortin receptor 1 variants and melanoma risk: a study of 2 European populations

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0001-7310%2809%2973167-9

Altered cell surface expression of human MC1R variant receptor alleles associated with red hair and skin cancer risk

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0001-7310%2809%2973167-9

Functional variation of MC1R alleles from red-haired individuals.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0001-7310%2809%2973167-9

Receptor function, dominant negative activity and phenotype correlations for MC1R variant alleles

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0001-7310%2809%2973167-9

Red hair is the null phenotype of MC1R.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0001-7310%2809%2973167-9

Melanocortin 1 receptor (MC1R) gene variants may increase the risk of melanoma in France independently of clinical risk factors and UV exposure

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0001-7310%2809%2973167-9

alpha-Melanocyte-stimulating hormone protects from ultraviolet radiation-induced apoptosis and DNA damage

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0001-7310%2809%2973167-9

Melanin content and MC1R function independently affect UVR-induced DNA damage in cultured human melanocytes.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0001-7310%2809%2973167-9

Lack of BRAF mutation in primary uveal melanoma.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0001-7310%2809%2973167-9

A pivotal role for ERK in the oncogenic behaviour of malignant melanoma?

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0001-7310%2809%2973167-9

The RAF proteins take centre stage

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0001-7310%2809%2973167-9

Fidelity and spatio-temporal control in MAP kinase (ERKs) signalling

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0001-7310%2809%2973167-9

Targeting the mitogen-activated protein kinase cascade to treat cancer

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0001-7310%2809%2973167-9

Ras mediates the cAMP-dependent activation of extracellular signal-regulated kinases (ERKs) in melanocytes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0001-7310%2809%2973167-9

Integrating signals between cAMP and the RAS/RAF/MEK/ERK signalling pathways. Based on the anniversary prize of the Gesellschaft für Biochemie und Molekularbiologie Lecture delivered on 5 July 2003 at the Special FEBS Meeting in Brussels

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0001-7310%2809%2973167-9

Ras and Rho regulation of the cell cycle and oncogenesis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0001-7310%2809%2973167-9

Analysis of the transcriptional program induced by Raf in epithelial cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0001-7310%2809%2973167-9

Overexpression of collagenase 1 (MMP-1) is mediated by the ERK pathway in invasive melanoma cells: role of BRAF mutation and fibroblast growth factor signaling

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0001-7310%2809%2973167-9

Induction of beta3-integrin gene expression by sustained activation of the Ras-regulated Raf-MEK-extracellular signal-regulated kinase signaling pathway

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0001-7310%2809%2973167-9

Oncogenic Ras and its role in tumor cell invasion and metastasis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0001-7310%2809%2973167-9

The complexity of Raf-1 regulation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0001-7310%2809%2973167-9

Endothelial apoptosis in Braf-deficient mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0001-7310%2809%2973167-9

Craf-1 protein kinase is essential for mouse development.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0001-7310%2809%2973167-9

Post-natal lethality and neurological and gastrointestinal defects in mice with targeted disruption of the A-Raf protein kinase gene.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0001-7310%2809%2973167-9

Mechanisms of regulating the Raf kinase family

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0001-7310%2809%2973167-9

The mouse B-raf gene encodes multiple protein isoforms with tissue-specific expression.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0001-7310%2809%2973167-9

Mutations of the BRAF gene in human cancer

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0001-7310%2809%2973167-9

Guilty as charged: B-RAF is a human oncogene

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0001-7310%2809%2973167-9

Mechanism of activation of the RAF-ERK signaling pathway by oncogenic mutations of B-RAF

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0001-7310%2809%2973167-9

The role of B-RAF in melanoma.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0001-7310%2809%2973167-9

Activating BRAF and N-Ras mutations in sporadic primary melanomas: an inverse association with allelic loss on chromosome 9.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0001-7310%2809%2973167-9

Somatic activation of KIT in distinct subtypes of melanoma

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0001-7310%2809%2973167-9

High frequency of BRAF mutations in nevi

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0001-7310%2809%2973167-9

High BRAF mutation frequency does not characterize all melanocytic tumor types.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0001-7310%2809%2973167-9

BRAF mutations are common somatic events in melanocytic nevi

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0001-7310%2809%2973167-9

Mutations of the BRAF gene in benign and malignant melanocytic lesions

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0001-7310%2809%2973167-9

BRAF mutations are sufficient to promote nevi formation and cooperate with p53 in the genesis of melanoma.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0001-7310%2809%2973167-9

V599EB-RAF is an oncogene in melanocytes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0001-7310%2809%2973167-9

Inhibition of growth and invasive ability of melanoma by inactivation of mutated BRAF with lentivirus-mediated RNA interference.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0001-7310%2809%2973167-9

Mutant V599EB-Raf regulates growth and vascular development of malignant melanoma tumors

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0001-7310%2809%2973167-9

Adhesion control of cyclin D1 and p27Kip1 levels is deregulated in melanoma cells through BRAF-MEK-ERK signaling

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0001-7310%2809%2973167-9

Loitering with intent: new evidence for the role of BRAF mutations in the proliferation of melanocytic lesions

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0001-7310%2809%2973167-9

The role of BRAF mutation and p53 inactivation during transformation of a subpopulation of primary human melanocytes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0001-7310%2809%2973167-9

Oncogenic Braf induces melanocyte senescence and melanoma in mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0001-7310%2809%2973167-9

Activation of the MAPK pathway is a common event in uveal melanomas although it rarely occurs through mutation of BRAF or RAS.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0001-7310%2809%2973167-9

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0001-7310%2809%2973167-9

Mechanisms of Ras protein targeting in mammalian cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0001-7310%2809%2973167-9

Biological and biochemical properties of human rasH genes mutated at codon 61.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0001-7310%2809%2973167-9

Analysis of N- and K-ras mutations in the distinctive tumor progression phases of melanoma.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0001-7310%2809%2973167-9

N-ras mutations in human cutaneous melanoma from sun-exposed body sites.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0001-7310%2809%2973167-9

N-ras mutations are common in melanomas from sun-exposed skin of humans but rare in mucosal membranes or unexposed skin

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0001-7310%2809%2973167-9

Suppression of oncogenic NRAS by RNA interference induces apoptosis of human melanoma cells.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0001-7310%2809%2973167-9

Pharmacogenetic candidate genes for melanoma

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0001-7310%2809%2973167-9

Integrative genomic analyses identify MITF as a lineage survival oncogene amplified in malignant melanoma

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0001-7310%2809%2973167-9

BRAFE600-associated senescence-like cell cycle arrest of human naevi

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0001-7310%2809%2973167-9

Metastasizing Melanoma Formation Caused by Expression of Activated N-RasQ61Kon an INK4a-Deficient Background

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0001-7310%2809%2973167-9