(Q60907791)

12 December 2020

The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors

1 reference

12 December 2020

The small GTP-binding protein rac regulates growth factor-induced membrane ruffling

1 reference

12 December 2020

p21 with a phenylalanine 28----leucine mutation reacts normally with the GTPase activating protein GAP but nevertheless has transforming properties

1 reference

12 December 2020

Microinjection of recombinant p21rho induces rapid changes in cell morphology

1 reference

12 December 2020

Molecular cloning and expression of a G25K cDNA, the human homolog of the yeast cell cycle gene CDC42

1 reference

12 December 2020

Molecular cloning of the gene for the human placental GTP-binding protein Gp (G25K): identification of this GTP-binding protein as the human homolog of the yeast cell-division-cycle protein CDC42

1 reference

12 December 2020

Three-dimensional structures of H-ras p21 mutants: molecular basis for their inability to function as signal switch molecules

1 reference

12 December 2020

Proton NMR studies of transforming and nontransforming H-ras p21 mutants.

1 reference

12 December 2020

Purification of the 22 kDa protein substrate of botulinum ADP-ribosyltransferase C3 from porcine brain cytosol and its characterization as a GTP-binding protein highly homologous to the rho gene product

1 reference

12 December 2020

The mammalian G protein rhoC is ADP-ribosylated by Clostridium botulinum exoenzyme C3 and affects actin microfilaments in Vero cells.

1 reference

12 December 2020

rac, a novel ras-related family of proteins that are botulinum toxin substrates

1 reference

12 December 2020

Molecular cloning and characterization of the human dbl proto-oncogene: evidence that its overexpression is sufficient to transform NIH/3T3 cells

1 reference

12 December 2020

Purification of the major GTP-binding proteins from human placental membranes

1 reference

12 December 2020

Coding sequence of human rho cDNAs clone 6 and clone 9

1 reference

12 December 2020

Nucleotide sequence of human rho cDNA clone 12.

1 reference

12 December 2020

Isolation of a new human oncogene from a diffuse B-cell lymphoma.

1 reference

12 December 2020

A novel ras-related gene family

1 reference

12 December 2020

Rho, rac, and cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia

1 reference

12 December 2020

Activation of Rac1, RhoA, and mitogen-activated protein kinases is required for Ras transformation

1 reference

12 December 2020

Physiological concentrations of purines and pyrimidines

1 reference

12 December 2020

A role for Rho in Ras transformation

1 reference

12 December 2020

Identification of a novel human Rho protein with unusual properties: GTPase deficiency and in vivo farnesylation

1 reference

12 December 2020

Guanine nucleotide binding properties of Rac2 mutant proteins and analysis of the responsiveness to guanine nucleotide dissociation stimulator

1 reference

12 December 2020

A novel Cdc42Hs mutant induces cellular transformation

1 reference

12 December 2020

Rho proteins induce metastatic properties in vivo

1 reference

12 December 2020

A new member of the Rho family, Rnd1, promotes disassembly of actin filament structures and loss of cell adhesion

1 reference

12 December 2020

Cloning, characterization, and chromosomal localization of a gene frequently deleted in human liver cancer (DLC-1) homologous to rat RhoGAP

1 reference

12 December 2020

Tools of the trade: use of dominant-inhibitory mutants of Ras-family GTPases

1 reference

12 December 2020

Cloning of a novel human Rac1b splice variant with increased expression in colorectal tumors

1 reference

12 December 2020

Rac1 in human breast cancer: overexpression, mutation analysis, and characterization of a new isoform, Rac1b

1 reference

12 December 2020

Crystal structure of Rnd3/RhoE: functional implications

1 reference

12 December 2020

Identification of an evolutionarily conserved superfamily of DOCK180-related proteins with guanine nucleotide exchange activity

1 reference

12 December 2020

Rnd proteins function as RhoA antagonists by activating p190 RhoGAP

1 reference

12 December 2020

1 reference

12 December 2020

Rho GTPases have diverse effects on the organization of the actin filament system

1 reference

12 December 2020

Alternative splicing of Rac1 generates Rac1b, a self-activating GTPase

1 reference

12 December 2020

Rho-family GTPases: it's not only Rac and Rho (and I like it).

1 reference

12 December 2020

RhoBTB2 is a substrate of the mammalian Cul3 ubiquitin ligase complex

1 reference

12 December 2020

Wrch1 is a GTPase-deficient Cdc42-like protein with unusual binding characteristics and cellular effects

1 reference

12 December 2020

Human RAS superfamily proteins and related GTPases

1 reference

12 December 2020

Rac1b, a tumor associated, constitutively active Rac1 splice variant, promotes cellular transformation

1 reference

12 December 2020

Atypical mechanism of regulation of the Wrch-1 Rho family small GTPase

1 reference

12 December 2020

Critical and distinct roles of amino- and carboxyl-terminal sequences in regulation of the biological activity of the Chp atypical Rho GTPase.

1 reference

12 December 2020

Transforming activity of the Rho family GTPase, Wrch-1, a Wnt-regulated Cdc42 homolog, is dependent on a novel carboxyl-terminal palmitoylation motif

1 reference

12 December 2020

Solution structure of an oncogenic mutant of Cdc42Hs

1 reference

12 December 2020

Function and regulation of Rnd proteins

1 reference

12 December 2020

Evolution of the Rho family of ras-like GTPases in eukaryotes

1 reference

12 December 2020

Current knowledge of the large RhoGAP family of proteins

1 reference

12 December 2020

Rho Family GTPase modification and dependence on CAAX motif-signaled posttranslational modification

1 reference

12 December 2020

Characterization of RhoBTB-dependent Cul3 ubiquitin ligase complexes--evidence for an autoregulatory mechanism

1 reference

12 December 2020

Rac activation and inactivation control plasticity of tumor cell movement

1 reference

12 December 2020

RhoBTB3: a Rho GTPase-family ATPase required for endosome to Golgi transport

1 reference

12 December 2020

RhoGDI signaling provides targets for cancer therapy

1 reference

12 December 2020

The 19-amino acid insertion in the tumor-associated splice isoform Rac1b confers specific binding to p120 catenin

1 reference

12 December 2020

The RhoA GEF Syx Is a Target of Rnd3 and Regulated via a Raf1-Like Ubiquitin-Related Domain

1 reference

12 December 2020

Ras superfamily GEFs and GAPs: validated and tractable targets for cancer therapy?

1 reference

12 December 2020

Rac1b recruits Dishevelled and β-catenin to Wnt target gene promoters independent of Wnt3A stimulation

1 reference

12 December 2020

Ras history: The saga continues

1 reference

12 December 2020

Perturbation of cytoskeleton dynamics by the opposing effects of Rac1 and Rac1b

1 reference

12 December 2020

A landscape of driver mutations in melanoma

1 reference

12 December 2020

Exome sequencing identifies recurrent somatic RAC1 mutations in melanoma

1 reference

12 December 2020

Deleted in liver cancer protein family in human malignancies (Review)

1 reference

12 December 2020

Matrix compliance regulates Rac1b localization, NADPH oxidase assembly, and epithelial-mesenchymal transition

1 reference

12 December 2020

New insight into the molecular switch mechanism of human Rho family proteins: shifting a paradigm

1 reference

12 December 2020

1 reference

12 December 2020

SH3-mediated targeting of Wrch1/RhoU by multiple adaptor proteins

1 reference

12 December 2020

RAC1P29S is a spontaneously activating cancer-associated GTPase

1 reference

12 December 2020

Transforming mutations of RAC guanosine triphosphatases in human cancers

1 reference

12 December 2020

14-3-3 proteins interact with a hybrid prenyl-phosphorylation motif to inhibit G proteins

1 reference

12 December 2020

Rho guanine nucleotide exchange factors: regulators of Rho GTPase activity in development and disease

1 reference

12 December 2020

Somatic RHOA mutation in angioimmunoblastic T cell lymphoma.

1 reference

12 December 2020

A recurrent inactivating mutation in RHOA GTPase in angioimmunoblastic T cell lymphoma

1 reference

12 December 2020

Dock-family exchange factors in cell migration and disease

1 reference

12 December 2020

Clinical and pathological associations of the activating RAC1 P29S mutation in primary cutaneous melanoma.

1 reference

12 December 2020

Rho regulation: DLC proteins in space and time

1 reference

12 December 2020

RAC1 P29S regulates PD-L1 expression in melanoma.

1 reference

12 December 2020

Catching Functional Modes and Structural Communication in Dbl Family Rho Guanine Nucleotide Exchange Factors.

1 reference

12 December 2020

Rho-modifying bacterial protein toxins

1 reference

12 December 2020

Juvenile myelomonocytic leukemia displays mutations in components of the RAS pathway and the PRC2 network.

1 reference

12 December 2020

Variegated RHOA mutations in adult T-cell leukemia/lymphoma.

1 reference

12 December 2020

The involvement of mutant Rac1 in the formation of invadopodia in cultured melanoma cells

1 reference

12 December 2020

Lamellipodia are crucial for haptotactic sensing and response

1 reference

12 December 2020

Atypical Rho GTPases of the RhoBTB Subfamily: Roles in Vesicle Trafficking and Tumorigenesis

1 reference

12 December 2020

Role of Rho-specific guanine nucleotide dissociation inhibitor α regulation in cell migration

1 reference

12 December 2020

Chemical screening identifies ROCK as a target for recovering mitochondrial function in Hutchinson-Gilford progeria syndrome

1 reference

12 December 2020

Interaction between Rho GTPases and 14-3-3 Proteins

1 reference

12 December 2020

Fast-cycling Rho GTPases.

1 reference

12 December 2020

RhoD localization and function is dependent on its GTP/GDP-bound state and unique N-terminal motif

1 reference

12 December 2020

RHO GTPases in cancer: known facts, open questions, and therapeutic challenges

1 reference

12 December 2020

Well-differentiated papillary mesothelioma of the peritoneum is genetically defined by mutually exclusive mutations in TRAF7 and CDC42.

1 reference

12 December 2020