(Q64245167)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30691108%20AND%20SRC:MED&resulttype=core&format=json

20 April 2020

title

Metabolic Reprogramming in Breast Cancer and Its Therapeutic Implications (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30691108%20AND%20SRC:MED&resulttype=core&format=json

20 April 2020

0 references

0 references

Resistance mechanisms

0 references

1 reference

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30691108%20AND%20SRC:MED&resulttype=core&format=json

20 April 2020

author name string

Nishant Gandhi

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30691108%20AND%20SRC:MED&resulttype=core&format=json

20 April 2020

language of work or name

English

0 references

publication date

26 January 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30691108%20AND%20SRC:MED&resulttype=core&format=json

20 April 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30691108%20AND%20SRC:MED&resulttype=core&format=json

20 April 2020

volume

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30691108%20AND%20SRC:MED&resulttype=core&format=json

20 April 2020

issue

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30691108%20AND%20SRC:MED&resulttype=core&format=json

Creative Commons Attribution 4.0 International

20 April 2020

page(s)

89

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copyright license

start time

26 January 2019

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

Tamoxifen induced changes in MCF7 human breast cancer: in vitro and in vivo studies using nuclear magnetic resonance spectroscopy and imaging

1 reference

12 December 2020

Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours

1 reference

12 December 2020

The epidemiology of breast cancer

1 reference

12 December 2020

Human chorionic gonadotropin and rat mammary cancer prevention.

1 reference

12 December 2020

Coordinate reciprocal trends in glycolytic and mitochondrial transcript accumulations during the in vitro differentiation of human myoblasts.

1 reference

12 December 2020

Metabolic studies of estrogen- and tamoxifen-treated human breast cancer cells by nuclear magnetic resonance spectroscopy

1 reference

12 December 2020

Chromosome 17 deletions and p53 gene mutations in colorectal carcinomas

1 reference

12 December 2020

Human cells lacking mtDNA: repopulation with exogenous mitochondria by complementation

1 reference

12 December 2020

Short-term hormone treatment as a chemopreventive method against mammary cancer initiation in rats

1 reference

12 December 2020

Tumors: wounds that do not heal. Similarities between tumor stroma generation and wound healing

1 reference

12 December 2020

Regulation of glycolytic enzyme RNA transcriptional rates by oxygen availability in skeletal muscle cells

1 reference

12 December 2020

Chemoprevention of N-nitroso-N-methylurea-induced mammary cancers by pretreatment with 17 beta-estradiol and progesterone

1 reference

12 December 2020

Age at first birth and breast cancer risk

1 reference

12 December 2020

Transcriptional regulation of genes encoding glycolytic enzymes by hypoxia-inducible factor 1

1 reference

12 December 2020

Transient Increase in the Risk of Breast Cancer after Giving Birth

1 reference

12 December 2020

Tumour incidence, spectrum and ploidy in mice with a large deletion in the p53 gene

1 reference

12 December 2020

Acidic pH enhances the invasive behavior of human melanoma cells

1 reference

12 December 2020

Improving cancer radiotherapy with 2-deoxy-D-glucose: phase I/II clinical trials on human cerebral gliomas.

1 reference

12 December 2020

Cloning of a novel receptor expressed in rat prostate and ovary

1 reference

12 December 2020

ER beta: identification and characterization of a novel human estrogen receptor

1 reference

12 December 2020

Apoptosis and remodeling of mammary gland tissue during involution proceeds through p53-independent pathways

1 reference

12 December 2020

Cloning, chromosomal localization, and functional analysis of the murine estrogen receptor beta

1 reference

12 December 2020

neu/ERBB2 cooperates with p53-172H during mammary tumorigenesis in transgenic mice

1 reference

12 December 2020

Glucose catabolism in cancer cells. The type II hexokinase promoter contains functionally active response elements for the tumor suppressor p53

1 reference

12 December 2020

Human estrogen receptor beta-gene structure, chromosomal localization, and expression pattern

1 reference

12 December 2020

The complete primary structure of human estrogen receptor beta (hER beta) and its heterodimerization with ER alpha in vivo and in vitro

1 reference

12 December 2020

Hormone levels and mammary epithelial cell proliferation in rats treated with a regimen of estradiol and progesterone that mimics the preventive effect of pregnancy against mammary cancer.

1 reference

12 December 2020

Moderate folate depletion increases plasma homocysteine and decreases lymphocyte DNA methylation in postmenopausal women

1 reference

12 December 2020

Hormone-induced refractoriness to mammary carcinogenesis in Wistar-Furth rats

1 reference

12 December 2020

Hypomethylation in cervical tissue: is there a correlation with folate status?

1 reference

12 December 2020

Delayed involution of the mammary epithelium in BALB/c-p53null mice

1 reference

12 December 2020

Inhibition of T cell proliferation by macrophage tryptophan catabolism

1 reference

12 December 2020

Estrogen receptor status by immunohistochemistry is superior to the ligand-binding assay for predicting response to adjuvant endocrine therapy in breast cancer

1 reference

12 December 2020

p53 is a transcriptional activator of the muscle-specific phosphoglycerate mutase gene and contributes in vivo to the control of its cardiac expression.

1 reference

12 December 2020

p53 and human cancer: the first ten thousand mutations.

1 reference

12 December 2020

Epigenetic inactivation of LKB1 in primary tumors associated with the Peutz-Jeghers syndrome

1 reference

12 December 2020

Functional differences between the amino-terminal domains of estrogen receptors alpha and beta

1 reference

12 December 2020

Genomic DNA methylation decreases in response to moderate folate depletion in elderly women.

1 reference

12 December 2020

Surfing the p53 network

1 reference

12 December 2020

Development of spontaneous mammary tumors in BALB/c p53 heterozygous mice. A model for Li-Fraumeni syndrome

1 reference

12 December 2020

Lactate elicits vascular endothelial growth factor from macrophages: a possible alternative to hypoxia

1 reference

12 December 2020

Use of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that overexpresses HER2.

1 reference

12 December 2020

Genetic interactions between tumor suppressors Brca1 and p53 in apoptosis, cell cycle and tumorigenesis.

1 reference

12 December 2020

Ferredoxin reductase affects p53-dependent, 5-fluorouracil-induced apoptosis in colorectal cancer cells

1 reference

12 December 2020

p53 is a potential mediator of pregnancy and hormone-induced resistance to mammary carcinogenesis

1 reference

12 December 2020

Lactate stimulates fibroblast expression of hyaluronan and CD44: the Warburg effect revisited

1 reference

12 December 2020

Distinct expression patterns of ER alpha and ER beta in normal human mammary gland

1 reference

12 December 2020

IFN-gamma and pro-inflammatory cytokine production by antigen-presenting cells is dictated by intracellular thiol redox status regulated by oxygen tension

1 reference

12 December 2020

Involvement of estrogen receptor beta in terminal differentiation of mammary gland epithelium

1 reference

12 December 2020

Nuclear genes involved in mitochondria-to-nucleus communication in breast cancer cells

1 reference

12 December 2020

Endocrine-responsive breast cancer and strategies for combating resistance

1 reference

12 December 2020

Effect of ovariectomy on adipose tissue of mice in the absence of estrogen receptor alpha (ERalpha): a potential role for estrogen receptor beta (ERbeta).

1 reference

12 December 2020

Glycolysis and glucose transporter 1 as markers of response to hormonal therapy in breast cancer

1 reference

12 December 2020

On the Origin of Cancer Cells

1 reference

12 December 2020

Extinction of experimental mammary cancer. I. Estradiol-17beta and progesterone

1 reference

12 December 2020

p53 function is required for hormone-mediated protection of mouse mammary tumorigenesis

1 reference

12 December 2020

Global analysis of ligand sensitivity of estrogen inducible and suppressible genes in MCF7/BUS breast cancer cells by DNA microarray

1 reference

12 December 2020

Estrogen receptor alpha in human breast cancer: occurrence and significance

1 reference

12 December 2020

The biological role of estrogen receptors alpha and beta in cancer

1 reference

12 December 2020

The favourable prognostic value of oestrogen receptor beta immunohistochemical expression in breast cancer

1 reference

12 December 2020

Progesterone receptor by immunohistochemistry and clinical outcome in breast cancer: a validation study

1 reference

12 December 2020

Promoter methylation of the PTEN gene is a common molecular change in breast cancer

1 reference

12 December 2020

AIF deficiency compromises oxidative phosphorylation

1 reference

12 December 2020

Hypoxia activates the capacity of tumor-associated carbonic anhydrase IX to acidify extracellular pH.

1 reference

12 December 2020

Breast cancer risk by age at birth, time since birth and time intervals between births: exploring interaction effects

1 reference

12 December 2020

Gain of function of a p53 hot spot mutation in a mouse model of Li-Fraumeni syndrome.

1 reference

12 December 2020

Glycolytic enzymes can modulate cellular life span

1 reference

12 December 2020

Anti-proliferative effect of estrogen in breast cancer cells that re-express ERalpha is mediated by aberrant regulation of cell cycle genes

1 reference

12 December 2020

1 reference

12 December 2020

Optimizing cancer radiotherapy with 2-deoxy-d-glucose dose escalation studies in patients with glioblastoma multiforme

1 reference

12 December 2020

Proteomic study reveals that proteins involved in metabolic and detoxification pathways are highly expressed in HER-2/neu-positive breast cancer

1 reference

12 December 2020

Macrophage responses to hypoxia: implications for tumor progression and anti-cancer therapies

1 reference

12 December 2020

Trastuzumab plus adjuvant chemotherapy for operable HER2-positive breast cancer

1 reference

12 December 2020

BRCA1 affects lipid synthesis through its interaction with acetyl-CoA carboxylase

1 reference

12 December 2020

Nuclear control of respiratory gene expression in mammalian cells

1 reference

12 December 2020

Estrogen receptor-alpha binds p53 tumor suppressor protein directly and represses its function

1 reference

12 December 2020

HIF-1-mediated expression of pyruvate dehydrogenase kinase: a metabolic switch required for cellular adaptation to hypoxia

1 reference

12 December 2020

HIF-1 mediates adaptation to hypoxia by actively downregulating mitochondrial oxygen consumption

1 reference

12 December 2020

Gonadal hormones determine sensitivity to central leptin and insulin.

1 reference

12 December 2020

Mitochondrial DNA mutations and mitochondrial DNA depletion in breast cancer

1 reference

12 December 2020

Genes regulated by estrogen in breast tumor cells in vitro are similarly regulated in vivo in tumor xenografts and human breast tumors

1 reference

12 December 2020

Mechanisms of disease: understanding resistance to HER2-targeted therapy in human breast cancer

1 reference

12 December 2020

p53 regulates mitochondrial respiration

1 reference

12 December 2020

Regulation of AIF expression by p53.

1 reference

12 December 2020

Impact of estrogen receptor beta on gene networks regulated by estrogen receptor alpha in breast cancer cells

1 reference

12 December 2020

TIGAR, a p53-inducible regulator of glycolysis and apoptosis

1 reference

12 December 2020

Altered sirtuin expression is associated with node-positive breast cancer

1 reference

12 December 2020

American Society of Clinical Oncology/College of American Pathologists guideline recommendations for human epidermal growth factor receptor 2 testing in breast cancer

1 reference

12 December 2020

Inhibitory effect of tumor cell-derived lactic acid on human T cells

1 reference

12 December 2020

Adaptation of energy metabolism in breast cancer brain metastases.

1 reference

12 December 2020

Estrogen receptor beta expression is associated with tamoxifen response in ERalpha-negative breast carcinoma

1 reference

12 December 2020

Direct evidence of lipid translocation between adipocytes and prostate cancer cells with imaging FTIR microspectroscopy

1 reference

12 December 2020

Systemic treatment with the antidiabetic drug metformin selectively impairs p53-deficient tumor cell growth

1 reference

12 December 2020

Estrogen receptor alpha inhibits p53-mediated transcriptional repression: implications for the regulation of apoptosis

1 reference

12 December 2020

Altered mammary gland development in the p53+/m mouse, a model of accelerated aging

1 reference

12 December 2020

Estradiol stimulates transcription of nuclear respiratory factor-1 and increases mitochondrial biogenesis.

1 reference

12 December 2020

Estrogen receptor alpha negative breast cancer patients: estrogen receptor beta as a therapeutic target

1 reference

12 December 2020

Estrogen Receptors alpha and beta as determinants of gene expression: influence of ligand, dose, and chromatin binding

1 reference

12 December 2020

p53 regulates glucose metabolism through an IKK-NF-kappaB pathway and inhibits cell transformation

1 reference

12 December 2020

Luteolin as a glycolysis inhibitor offers superior efficacy and lesser toxicity of doxorubicin in breast cancer cells

1 reference

12 December 2020

Clinical importance of estrogen receptor-beta evaluation in breast cancer patients treated with adjuvant tamoxifen therapy

1 reference

12 December 2020

Nuclear and cytoplasmic expression of ERbeta1, ERbeta2, and ERbeta5 identifies distinct prognostic outcome for breast cancer patients

1 reference

12 December 2020

A divergent role for estrogen receptor-beta in node-positive and node-negative breast cancer classified according to molecular subtypes: an observational prospective study

1 reference

12 December 2020

Cancer cell metabolism: Warburg and beyond

1 reference

12 December 2020

Glucose deprivation inhibits multiple key gene expression events and effector functions in CD8+ T cells

1 reference

12 December 2020

AKT alters genome-wide estrogen receptor alpha binding and impacts estrogen signaling in breast cancer.

1 reference

12 December 2020

IDH1 mutations at residue p.R132 (IDH1(R132)) occur frequently in high-grade gliomas but not in other solid tumors

1 reference

12 December 2020

Pleiotropic combinatorial transcriptomes of human breast cancer cells exposed to mixtures of dietary phytoestrogens

1 reference

12 December 2020

MUC1-induced alterations in a lipid metabolic gene network predict response of human breast cancers to tamoxifen treatment

1 reference

12 December 2020

Transcriptional regulation of estrogen receptor-alpha by p53 in human breast cancer cells

1 reference

12 December 2020

Participation of ERalpha and ERbeta in glucose homeostasis in skeletal muscle and white adipose tissue

1 reference

12 December 2020

Blinded by the Light: The Growing Complexity of p53

1 reference

12 December 2020

Targeting glucose metabolism with 2-deoxy-D-glucose for improving cancer therapy.

1 reference

12 December 2020

Type and frequency of IDH1 and IDH2 mutations are related to astrocytic and oligodendroglial differentiation and age: a study of 1,010 diffuse gliomas.

1 reference

12 December 2020

Mitochondrial dysfunction in human breast cancer cells and their transmitochondrial cybrids

1 reference

12 December 2020

Upregulation of lactate dehydrogenase A by ErbB2 through heat shock factor 1 promotes breast cancer cell glycolysis and growth.

1 reference

12 December 2020

p53 improves aerobic exercise capacity and augments skeletal muscle mitochondrial DNA content

1 reference

12 December 2020

The tumor suppressor p53 regulates polarity of self-renewing divisions in mammary stem cells.

1 reference

12 December 2020

Genome-wide dynamics of chromatin binding of estrogen receptors alpha and beta: mutual restriction and competitive site selection

1 reference

12 December 2020

Positive cross-talk between estrogen receptor and NF-kappaB in breast cancer

1 reference

12 December 2020

The reverse Warburg effect: aerobic glycolysis in cancer associated fibroblasts and the tumor stroma

1 reference

12 December 2020

The common feature of leukemia-associated IDH1 and IDH2 mutations is a neomorphic enzyme activity converting alpha-ketoglutarate to 2-hydroxyglutarate

1 reference

12 December 2020

17beta-estradiol supplementation attenuates ovariectomy-induced increases in ATGL signaling and reduced perilipin expression in visceral adipose tissue

1 reference

12 December 2020

Phosphate-activated glutaminase (GLS2), a p53-inducible regulator of glutamine metabolism and reactive oxygen species

1 reference

12 December 2020

Minireview: Estrogen receptor-beta: mechanistic insights from recent studies

1 reference

12 December 2020

Glutaminase 2, a novel p53 target gene regulating energy metabolism and antioxidant function

1 reference

12 December 2020

The regulation of energy metabolism and the IGF-1/mTOR pathways by the p53 protein

1 reference

12 December 2020

American Society of Clinical Oncology/College Of American Pathologists guideline recommendations for immunohistochemical testing of estrogen and progesterone receptors in breast cancer

1 reference

12 December 2020

IDH1 and IDH2 mutation analysis in chronic- and blast-phase myeloproliferative neoplasms.

1 reference

12 December 2020

Metastasis suppression by adiponectin: LKB1 rises up to the challenge

1 reference

12 December 2020

IDH1 mutations in patients with myelodysplastic syndromes are associated with an unfavorable prognosis.

1 reference

12 December 2020

Genome-wide analysis of estrogen receptor alpha DNA binding and tethering mechanisms identifies Runx1 as a novel tethering factor in receptor-mediated transcriptional activation

1 reference

12 December 2020

Functional effects of cancer mitochondria on energy metabolism and tumorigenesis: utility of transmitochondrial cybrids

1 reference

12 December 2020

Parenteral 17beta-estradiol decreases fasting blood glucose levels in non-obese mice with short-term ovariectomy

1 reference

12 December 2020

Mechanisms of estrogen receptor antagonism toward p53 and its implications in breast cancer therapeutic response and stem cell regulation.

1 reference

12 December 2020

Oxidative stress in cancer associated fibroblasts drives tumor-stroma co-evolution: A new paradigm for understanding tumor metabolism, the field effect and genomic instability in cancer cells

1 reference

12 December 2020

The autophagic tumor stroma model of cancer: Role of oxidative stress and ketone production in fueling tumor cell metabolism

1 reference

12 December 2020

17beta-estradiol augments 18F-FDG uptake and glycolysis of T47D breast cancer cells via membrane-initiated rapid PI3K-Akt activation

1 reference

12 December 2020

BRCA1-mutated and basal-like breast cancers have similar aCGH profiles and a high incidence of protein truncating TP53 mutations

1 reference

12 December 2020

Regulation of cancer cell metabolism

1 reference

12 December 2020

Aberrant promoter CpG methylation is a mechanism for impaired PHD3 expression in a diverse set of malignant cells

1 reference

12 December 2020

p53 regulates biosynthesis through direct inactivation of glucose-6-phosphate dehydrogenase

1 reference

12 December 2020

SIRT3 opposes reprogramming of cancer cell metabolism through HIF1α destabilization

1 reference

12 December 2020

Cancer-associated adipocytes exhibit an activated phenotype and contribute to breast cancer invasion

1 reference

12 December 2020

Overcoming trastuzumab resistance in breast cancer by targeting dysregulated glucose metabolism.

1 reference

12 December 2020

A rapid, extensive, and transient transcriptional response to estrogen signaling in breast cancer cells

1 reference

12 December 2020

Estrogen receptor silencing induces epithelial to mesenchymal transition in human breast cancer cells

1 reference

12 December 2020

MYC and Breast Cancer

1 reference

12 December 2020

Parkin, a p53 target gene, mediates the role of p53 in glucose metabolism and the Warburg effect

1 reference

12 December 2020

Adipocytes promote ovarian cancer metastasis and provide energy for rapid tumor growth

1 reference

12 December 2020

ERα-dependent E2F transcription can mediate resistance to estrogen deprivation in human breast cancer

1 reference

12 December 2020

ROS-mediated p53 induction of Lpin1 regulates fatty acid oxidation in response to nutritional stress

1 reference

12 December 2020

p53 negatively regulates transcription of the pyruvate dehydrogenase kinase Pdk2

1 reference

12 December 2020

Glutamine fuels a vicious cycle of autophagy in the tumor stroma and oxidative mitochondrial metabolism in epithelial cancer cells: implications for preventing chemotherapy resistance

1 reference

12 December 2020

Mutant p53 disrupts mammary tissue architecture via the mevalonate pathway

1 reference

12 December 2020

Glucose oxidation modulates anoikis and tumor metastasis.

1 reference

12 December 2020

The genomic and transcriptomic architecture of 2,000 breast tumours reveals novel subgroups

1 reference

12 December 2020

Research resource: Transcriptional profiling in a cellular model of breast cancer reveals functional and mechanistic differences between clinically relevant SERM and between SERM/estrogen complexes

1 reference

12 December 2020

The Skp2-SCF E3 ligase regulates Akt ubiquitination, glycolysis, herceptin sensitivity, and tumorigenesis

1 reference

12 December 2020

Tumor suppression in the absence of p53-mediated cell-cycle arrest, apoptosis, and senescence

1 reference

12 December 2020

Whole-genome analysis informs breast cancer response to aromatase inhibition

1 reference

12 December 2020

The gain of function of p53 cancer mutant in promoting mammary tumorigenesis

1 reference

12 December 2020

Differential gene expression in tamoxifen-resistant breast cancer cells revealed by a new analytical model of RNA-Seq data

1 reference

12 December 2020

Estrogen modulates metabolic pathway adaptation to available glucose in breast cancer cells

1 reference

12 December 2020

Estrogen receptor prevents p53-dependent apoptosis in breast cancer

1 reference

12 December 2020

BRCA1 mutations drive oxidative stress and glycolysis in the tumor microenvironment: implications for breast cancer prevention with antioxidant therapies

1 reference

12 December 2020

Cooperativity of Rb, Brca1, and p53 in malignant breast cancer evolution

1 reference

12 December 2020

Receptor tyrosine kinase ErbB2 translocates into mitochondria and regulates cellular metabolism

1 reference

12 December 2020

A new role of p53 in regulating lipid metabolism

1 reference

12 December 2020

p53-Dependent regulation of metabolic function through transcriptional activation of pantothenate kinase-1 gene

1 reference

12 December 2020

Depletion of the novel p53-target gene carnitine palmitoyltransferase 1C delays tumor growth in the neurofibromatosis type I tumor model

1 reference

12 December 2020

Manganese superoxide dismutase promotes anoikis resistance and tumor metastasis

1 reference

12 December 2020

Loss of FBP1 by Snail-mediated repression provides metabolic advantages in basal-like breast cancer.

1 reference

12 December 2020

Increased oxidative metabolism in the Li-Fraumeni syndrome

1 reference

12 December 2020

A bi-faceted role of estrogen receptor β in breast cancer

1 reference

12 December 2020

Crosstalk from non-cancerous mitochondria can inhibit tumor properties of metastatic cells by suppressing oncogenic pathways

1 reference

12 December 2020

Somatic loss of p53 leads to stem/progenitor cell amplification in both mammary epithelial compartments, basal and luminal.

1 reference

12 December 2020

Posttranscriptional control of T cell effector function by aerobic glycolysis

1 reference

12 December 2020

Antioxidant enzymes mediate survival of breast cancer cells deprived of extracellular matrix.

1 reference

12 December 2020

Estrogen receptor β activation impairs mitochondrial oxidative metabolism and affects malignant mesothelioma cell growth in vitro and in vivo.

1 reference

12 December 2020

Tissue-specific isoform switch and DNA hypomethylation of the pyruvate kinase PKM gene in human cancers.

1 reference

12 December 2020

Optical metabolic imaging identifies glycolytic levels, subtypes, and early-treatment response in breast cancer

1 reference

12 December 2020

Tumor suppressor p53 and estrogen receptors in nuclear-mitochondrial communication

1 reference

12 December 2020

Mitochondrial retrograde signaling induces epithelial-mesenchymal transition and generates breast cancer stem cells

1 reference

12 December 2020

Support of a bi-faceted role of estrogen receptor β (ERβ) in ERα-positive breast cancer cells

1 reference

12 December 2020

MYC-driven accumulation of 2-hydroxyglutarate is associated with breast cancer prognosis.

1 reference

12 December 2020

Tumour-associated mutant p53 drives the Warburg effect

1 reference

12 December 2020

JMJD5 regulates PKM2 nuclear translocation and reprograms HIF-1α-mediated glucose metabolism.

1 reference

12 December 2020

Invasive lobular carcinoma cell lines are characterized by unique estrogen-mediated gene expression patterns and altered tamoxifen response

1 reference

12 December 2020

Targeting arginine-dependent cancers with arginine-degrading enzymes: opportunities and challenges

1 reference

12 December 2020

Estradiol stimulates glucose metabolism via 6-phosphofructo-2-kinase (PFKFB3).

1 reference

12 December 2020

SLC25A1, or CIC, is a novel transcriptional target of mutant p53 and a negative tumor prognostic marker

1 reference

12 December 2020

A DERL3-associated defect in the degradation of SLC2A1 mediates the Warburg effect

1 reference

12 December 2020

Isocitrate dehydrogenase 1 (IDH1) mutation in breast adenocarcinoma is associated with elevated levels of serum and urine 2-hydroxyglutarate

1 reference

12 December 2020

Gain-of-function mutant p53 promotes cell growth and cancer cell metabolism via inhibition of AMPK activation.

1 reference

12 December 2020

Ribosomal protein-Mdm2-p53 pathway coordinates nutrient stress with lipid metabolism by regulating MCD and promoting fatty acid oxidation

1 reference

12 December 2020

BRCA1 and estrogen/estrogen receptor in breast cancer: where they interact?

1 reference

12 December 2020

Akt-dependent metabolic reprogramming regulates tumor cell histone acetylation

1 reference

12 December 2020

BRCA1 induces major energetic metabolism reprogramming in breast cancer cells.

1 reference

12 December 2020

Bromodomain protein BRD4 is required for estrogen receptor-dependent enhancer activation and gene transcription

1 reference

12 December 2020

Fructose-1,6-bisphosphatase opposes renal carcinoma progression

1 reference

12 December 2020

A joint analysis of metabolomics and genetics of breast cancer

1 reference

12 December 2020

Mitochondrial dysfunction in some triple-negative breast cancer cell lines: role of mTOR pathway and therapeutic potential

1 reference

12 December 2020

PGC-1α mediates mitochondrial biogenesis and oxidative phosphorylation in cancer cells to promote metastasis

1 reference

12 December 2020

ERβ1: characterization, prognosis, and evaluation of treatment strategies in ERα-positive and -negative breast cancer

1 reference

12 December 2020

Transcriptomic analysis identifies gene networks regulated by estrogen receptor α (ERα) and ERβ that control distinct effects of different botanical estrogens

1 reference

12 December 2020

Metabolic profile of triple-negative breast cancer in African-American women reveals potential biomarkers of aggressive disease.

1 reference

12 December 2020

Pre-clinical study of drug combinations that reduce breast cancer burden due to aberrant mTOR and metabolism promoted by LKB1 loss

1 reference

12 December 2020

Metabolic characterization of triple negative breast cancer

1 reference

12 December 2020

Gain of glucose-independent growth upon metastasis of breast cancer cells to the brain

1 reference

12 December 2020

Mitochondrial genome acquisition restores respiratory function and tumorigenic potential of cancer cells without mitochondrial DNA.

1 reference

12 December 2020

Acetyl-CoA synthetase 2 promotes acetate utilization and maintains cancer cell growth under metabolic stress

1 reference

12 December 2020

The emerging roles of YAP and TAZ in cancer

1 reference

12 December 2020

Glutathione and thioredoxin antioxidant pathways synergize to drive cancer initiation and progression

1 reference

12 December 2020

Differential expression of lipid metabolism-related proteins in different breast cancer subtypes.

1 reference

12 December 2020

Aerobic glycolysis tunes YAP/TAZ transcriptional activity

1 reference

12 December 2020

Metabolic reprogramming in triple-negative breast cancer through Myc suppression of TXNIP

1 reference

12 December 2020

p53 in survival, death and metabolic health: a lifeguard with a licence to kill

1 reference

12 December 2020

Inhibition of Aerobic Glycolysis Represses Akt/mTOR/HIF-1α Axis and Restores Tamoxifen Sensitivity in Antiestrogen-Resistant Breast Cancer Cells

1 reference

12 December 2020

Current approaches in treatment of triple-negative breast cancer

1 reference

12 December 2020

Metabolic Competition in the Tumor Microenvironment Is a Driver of Cancer Progression

1 reference

12 December 2020

PDK1-Dependent Metabolic Reprogramming Dictates Metastatic Potential in Breast Cancer

1 reference

12 December 2020

Metabolic plasticity of metastatic breast cancer cells: adaptation to changes in the microenvironment.

1 reference

12 December 2020

Estrogen receptor-α directly regulates the hypoxia-inducible factor 1 pathway associated with antiestrogen response in breast cancer

1 reference

12 December 2020

p53 as guardian of the mitochondrial genome

1 reference

12 December 2020

HER2 Signaling Drives DNA Anabolism and Proliferation through SRC-3 Phosphorylation and E2F1-Regulated Genes

1 reference

12 December 2020

Self-renewal of CD133(hi) cells by IL6/Notch3 signalling regulates endocrine resistance in metastatic breast cancer

1 reference

12 December 2020

ERβ decreases the invasiveness of triple-negative breast cancer cells by regulating mutant p53 oncogenic function

1 reference

12 December 2020

Fatty Acid Oxidation-Driven Src Links Mitochondrial Energy Reprogramming and Oncogenic Properties in Triple-Negative Breast Cancer.

1 reference

12 December 2020

Inhibition of fatty acid oxidation as a therapy for MYC-overexpressing triple-negative breast cancer

1 reference

12 December 2020

TP53 mutation, mitochondria and cancer

1 reference

12 December 2020

Cancer metabolism: a therapeutic perspective

1 reference

12 December 2020

The somatic mutation profiles of 2,433 breast cancers refines their genomic and transcriptomic landscapes

1 reference

12 December 2020

Germline BRCA1 mutation reprograms breast epithelial cell metabolism towards mitochondrial-dependent biosynthesis: evidence for metformin-based "starvation" strategies in BRCA1 carriers.

1 reference

12 December 2020

Targeting isocitrate dehydrogenase (IDH) in cancer.

1 reference

12 December 2020

Fundamentals of cancer metabolism

1 reference

12 December 2020

Repression of phosphoglycerate dehydrogenase sensitizes triple-negative breast cancer to doxorubicin

1 reference

12 December 2020

Nuclear respiratory factor-1 and bioenergetics in tamoxifen-resistant breast cancer cells.

1 reference

12 December 2020

Metabolic Reprogramming by the PI3K-Akt-mTOR Pathway in Cancer.

1 reference

12 December 2020

Inhibition of 6-phosphofructo-2-kinase (PFKFB3) suppresses glucose metabolism and the growth of HER2+ breast cancer

1 reference

12 December 2020

Collagen Matrix Density Drives the Metabolic Shift in Breast Cancer Cells.

1 reference

12 December 2020

DNAJA1 controls the fate of misfolded mutant p53 through the mevalonate pathway.

1 reference

12 December 2020

Phosphoglycerate mutase 1 promotes cancer cell migration independent of its metabolic activity

1 reference

12 December 2020

Acetate Recapturing by Nuclear Acetyl-CoA Synthetase 2 Prevents Loss of Histone Acetylation during Oxygen and Serum Limitation

1 reference

12 December 2020

Targeting Metabolic Remodeling in Triple Negative Breast Cancer in a Murine Model

1 reference

12 December 2020

The branched-chain amino acid transaminase 1 sustains growth of antiestrogen-resistant and ERα-negative breast cancer

1 reference

12 December 2020

Neuromedin U alters bioenergetics and expands the cancer stem cell phenotype in HER2-positive breast cancer.

1 reference

12 December 2020

Estrogen Receptor β as a Therapeutic Target in Breast Cancer Stem Cells.

1 reference

12 December 2020

In vivo Reprogramming of Cancer Metabolism by MYC.

1 reference

12 December 2020

Proline metabolism supports metastasis formation and could be inhibited to selectively target metastasizing cancer cells

1 reference

12 December 2020

Metabolic shifts in residual breast cancer drive tumor recurrence

1 reference

12 December 2020

Inhibition of glycolysis by a novel EGFR/HER2 inhibitor KU004 suppresses the growth of HER2+ cancer

1 reference

12 December 2020

Estrogen Receptor-β Modulation of the ERα-p53 Loop Regulating Gene Expression, Proliferation, and Apoptosis in Breast Cancer.

1 reference

12 December 2020

Post-transcriptional regulation of ERBB2 by miR26a/b and HuR confers resistance to tamoxifen in estrogen receptor-positive breast cancer cells.

1 reference

12 December 2020

Somatic loss of estrogen receptor beta and p53 synergize to induce breast tumorigenesis

1 reference

12 December 2020

Citrate Suppresses Tumor Growth in Multiple Models through Inhibition of Glycolysis, the Tricarboxylic Acid Cycle and the IGF-1R Pathway.

1 reference

12 December 2020

Nuclear Acetyl-CoA Production by ACLY Promotes Homologous Recombination.

1 reference

12 December 2020

The miR-29 transcriptome in endocrine-sensitive and resistant breast cancer cells.

1 reference

12 December 2020

Metabolic profiling of triple-negative breast cancer cells reveals metabolic vulnerabilities.

1 reference

12 December 2020

PGC-1α Promotes Breast Cancer Metastasis and Confers Bioenergetic Flexibility against Metabolic Drugs.

1 reference

12 December 2020

Effect of Mutant p53 Proteins on Glycolysis and Mitochondrial Metabolism.

1 reference

12 December 2020

Metabolic recycling of ammonia via glutamate dehydrogenase supports breast cancer biomass.

1 reference

12 December 2020

t-Darpp Activates IGF-1R Signaling to Regulate Glucose Metabolism in Trastuzumab-Resistant Breast Cancer Cells

1 reference

12 December 2020

The receptor tyrosine kinase EphA2 promotes glutamine metabolism in tumors by activating the transcriptional coactivators YAP and TAZ.

1 reference

12 December 2020

BRCA1 through Its E3 Ligase Activity Regulates the Transcription Factor Oct1 and Carbohydrate Metabolism.

1 reference

12 December 2020

Adipocyte/breast cancer cell crosstalk in obesity interferes with the anti-proliferative efficacy of tamoxifen.

1 reference

12 December 2020

Multifaceted Roles of Interleukin-6 in Adipocyte-Breast Cancer Cell Interaction.

1 reference

12 December 2020

Uncoupling effects of estrogen receptor α on LKB1/AMPK interaction upon adiponectin exposure in breast cancer.

1 reference

12 December 2020

Transketolase Regulates the Metabolic Switch to Control Breast Cancer Cell Metastasis via the α-Ketoglutarate Signaling Pathway

1 reference

12 December 2020

FGFR4 Links Glucose Metabolism and Chemotherapy Resistance in Breast Cancer.

1 reference

12 December 2020

Global metabolite profiling analysis of lipotoxicity in HER2/neu-positive breast cancer cells.

1 reference

12 December 2020

Urea Cycle Dysregulation Generates Clinically Relevant Genomic and Biochemical Signatures

1 reference

12 December 2020

Intratumor lactate levels reflect HER2 addiction status in HER2-positive breast cancer

1 reference

12 December 2020

Metabolic Frugality Marks Cancer Cells for Immune Targeting

1 reference

12 December 2020

Elucidating the novel BRCA1 function as a non-genomic metabolic restraint in ER-positive breast cancer cell lines

1 reference

12 December 2020

Identifiers

DOI

10.3390/CELLS8020089

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30691108%20AND%20SRC:MED&resulttype=core&format=json

20 April 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30691108%20AND%20SRC:MED&resulttype=core&format=json

20 April 2020

1 reference