(Q64921197)

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Premature Physiologic Aging as a Paradigm for Understanding Increased Risk of Adverse Health Across the Lifespan of Survivors of Childhood Cancer.

scientific article published on 6 June 2018

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Europe PubMed Central

PMC publication ID

1 July 2019

http://europepmc.org/abstract/PMC/6553838

Premature Physiologic Aging as a Paradigm for Understanding Increased Risk of Adverse Health Across the Lifespan of Survivors of Childhood Cancer. (English)

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Europe PubMed Central

PMC publication ID

1 July 2019

http://europepmc.org/abstract/PMC/6553838

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based on heuristic

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Kirsten K Ness

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Europe PubMed Central

PMC publication ID

1 July 2019

http://europepmc.org/abstract/PMC/6553838

author name string

James L Kirkland

2

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Europe PubMed Central

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1 July 2019

http://europepmc.org/abstract/PMC/6553838

Maria Monica Gramatges

3

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Europe PubMed Central

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1 July 2019

http://europepmc.org/abstract/PMC/6553838

Zhaoming Wang

4

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Europe PubMed Central

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1 July 2019

http://europepmc.org/abstract/PMC/6553838

Mondira Kundu

5

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Europe PubMed Central

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1 July 2019

http://europepmc.org/abstract/PMC/6553838

Kelly McCastlain

6

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Europe PubMed Central

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1 July 2019

http://europepmc.org/abstract/PMC/6553838

Xiujie Li-Harms

7

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Europe PubMed Central

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1 July 2019

http://europepmc.org/abstract/PMC/6553838

Jinghui Zhang

8

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Europe PubMed Central

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1 July 2019

http://europepmc.org/abstract/PMC/6553838

Tamar Tchkonia

9

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Europe PubMed Central

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1 July 2019

http://europepmc.org/abstract/PMC/6553838

Saskia Martine Francesca Pluijm

10

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Europe PubMed Central

PMC publication ID

1 July 2019

http://europepmc.org/abstract/PMC/6553838

Gregory T Armstrong

11

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Europe PubMed Central

PMC publication ID

1 July 2019

http://europepmc.org/abstract/PMC/6553838

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publication date

6 June 2018

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Europe PubMed Central

PMC publication ID

1 July 2019

http://europepmc.org/abstract/PMC/6553838

Journal of Clinical Oncology

1 reference

Europe PubMed Central

PMC publication ID

1 July 2019

http://europepmc.org/abstract/PMC/6553838

36

1 reference

Europe PubMed Central

PMC publication ID

1 July 2019

http://europepmc.org/abstract/PMC/6553838

21

1 reference

Europe PubMed Central

PMC publication ID

1 July 2019

http://europepmc.org/abstract/PMC/6553838

2206-2215

1 reference

Europe PubMed Central

PMC publication ID

1 July 2019

http://europepmc.org/abstract/PMC/6553838

Telomere length predicts replicative capacity of human fibroblasts

1 reference

https://pubmed.ncbi.nlm.nih.gov/29874132

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Senescent human fibroblasts resist programmed cell death, and failure to suppress bcl2 is involved

1 reference

https://pubmed.ncbi.nlm.nih.gov/29874132

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence for a mitotic clock in human hematopoietic stem cells: loss of telomeric DNA with age.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29874132

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A deletion of mitochondrial DNA in murine doxorubicin-induced cardiotoxicity

1 reference

https://pubmed.ncbi.nlm.nih.gov/29874132

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mitochondrial DNA damage is more extensive and persists longer than nuclear DNA damage in human cells following oxidative stress

1 reference

https://pubmed.ncbi.nlm.nih.gov/29874132

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inflamm-aging. An evolutionary perspective on immunosenescence

1 reference

https://pubmed.ncbi.nlm.nih.gov/29874132

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of exercise on the mitochondrial DNA content of peripheral blood in healthy women.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29874132

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cross-sectional and prospective relationships of interleukin-6 and C-reactive protein with physical performance in elderly persons: MacArthur studies of successful aging

1 reference

https://pubmed.ncbi.nlm.nih.gov/29874132

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Frailty in older adults: evidence for a phenotype

1 reference

https://pubmed.ncbi.nlm.nih.gov/29874132

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Telomere length in breast cancer patients before and after chemotherapy with or without stem cell transplantation

1 reference

https://pubmed.ncbi.nlm.nih.gov/29874132

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Relationship of interleukin-6 and tumor necrosis factor-alpha with muscle mass and muscle strength in elderly men and women: the Health ABC Study

1 reference

https://pubmed.ncbi.nlm.nih.gov/29874132

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Aging and genome maintenance: lessons from the mouse?

1 reference

https://pubmed.ncbi.nlm.nih.gov/29874132

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mitochondrial DNA mutations in primary leukemia cells after chemotherapy: clinical significance and therapeutic implications.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29874132

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Telomere length shortening in non-Hodgkin's lymphoma patients undergoing chemotherapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/29874132

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Time-Dependent and Tissue-Specific Accumulation of mtDNA and Respiratory Chain Defects in Chronic Doxorubicin Cardiomyopathy

1 reference

https://pubmed.ncbi.nlm.nih.gov/29874132

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Carcinogenesis Young Investigator Award. Telomere epigenetics: a higher-order control of telomere length in mammalian cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/29874132

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transcripts of aging

1 reference

https://pubmed.ncbi.nlm.nih.gov/29874132

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Premature ageing in mice expressing defective mitochondrial DNA polymerase

1 reference

https://pubmed.ncbi.nlm.nih.gov/29874132

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mitochondrial DNA mutations in human disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/29874132

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pathways connecting telomeres and p53 in senescence, apoptosis, and cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/29874132

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effects of physical activity on serum C-reactive protein and inflammatory markers: a systematic review

1 reference

https://pubmed.ncbi.nlm.nih.gov/29874132

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mitochondrial DNA mutations, oxidative stress, and apoptosis in mammalian aging

1 reference

https://pubmed.ncbi.nlm.nih.gov/29874132

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inflammatory Markers and Loss of Muscle Mass (Sarcopenia) and Strength

1 reference

https://pubmed.ncbi.nlm.nih.gov/29874132

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Epigenetics: a landscape takes shape

1 reference

https://pubmed.ncbi.nlm.nih.gov/29874132

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Insulin Resistance and Inflammation as Precursors of Frailty

1 reference

https://pubmed.ncbi.nlm.nih.gov/29874132

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

High innate production capacity of tumor necrosis factor-alpha and decline of handgrip strength in old age

1 reference

https://pubmed.ncbi.nlm.nih.gov/29874132

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Telomeres: hallmarks of radiosensitivity.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29874132

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Telomere length inversely correlates with radiosensitivity in human carcinoma cells with the same tissue background

1 reference

https://pubmed.ncbi.nlm.nih.gov/29874132

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cisplatin-mediated impairment of mitochondrial DNA metabolism inversely correlates with glutathione levels

1 reference

https://pubmed.ncbi.nlm.nih.gov/29874132

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oncogene-induced senescence relayed by an interleukin-dependent inflammatory network

1 reference

https://pubmed.ncbi.nlm.nih.gov/29874132

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Senescence-associated secretory phenotypes reveal cell-nonautonomous functions of oncogenic RAS and the p53 tumor suppressor

1 reference

https://pubmed.ncbi.nlm.nih.gov/29874132

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Senescence-messaging secretome: SMS-ing cellular stress

1 reference

https://pubmed.ncbi.nlm.nih.gov/29874132

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inflammation and frailty measures in older people

1 reference

https://pubmed.ncbi.nlm.nih.gov/29874132

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Higher inflammatory marker levels in older persons: associations with 5-year change in muscle mass and muscle strength

1 reference

https://pubmed.ncbi.nlm.nih.gov/29874132

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A crucial role for adipose tissue p53 in the regulation of insulin resistance

1 reference

https://pubmed.ncbi.nlm.nih.gov/29874132

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Influence of the polymorphism in candidate genes on late cardiac damage in patients treated due to acute leukemia in childhood

1 reference

https://pubmed.ncbi.nlm.nih.gov/29874132

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mitochondrial fusion is required for mtDNA stability in skeletal muscle and tolerance of mtDNA mutations

1 reference

https://pubmed.ncbi.nlm.nih.gov/29874132

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Telomere length is inherited with resetting of the telomere set-point.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29874132

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fat tissue, aging, and cellular senescence

1 reference

https://pubmed.ncbi.nlm.nih.gov/29874132

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Telomere length in blood, buccal cells, and fibroblasts from patients with inherited bone marrow failure syndromes

1 reference

https://pubmed.ncbi.nlm.nih.gov/29874132

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cisplatin induced mitochondrial DNA damage in dorsal root ganglion neurons.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29874132

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neurocognitive functioning and health-related behaviours in adult survivors of childhood cancer: a report from the Childhood Cancer Survivor Study

1 reference

https://pubmed.ncbi.nlm.nih.gov/29874132

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The association of telomere length and cancer: a meta-analysis

1 reference

https://pubmed.ncbi.nlm.nih.gov/29874132

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cumulative inflammatory load is associated with short leukocyte telomere length in the Health, Aging and Body Composition Study

1 reference

https://pubmed.ncbi.nlm.nih.gov/29874132

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Shortened telomere length is associated with increased risk of cancer: a meta-analysis

1 reference

https://pubmed.ncbi.nlm.nih.gov/29874132

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Higher levels of fatigue are associated with higher CRP levels in disease-free breast cancer survivors.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29874132

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Anthracycline-related cardiomyopathy after childhood cancer: role of polymorphisms in carbonyl reductase genes--a report from the Children's Oncology Group.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29874132

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A senescent cell bystander effect: senescence-induced senescence

1 reference

https://pubmed.ncbi.nlm.nih.gov/29874132

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Telomeric DNA damage is irreparable and causes persistent DNA-damage-response activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/29874132

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of a caloric restriction weight loss diet and exercise on inflammatory biomarkers in overweight/obese postmenopausal women: a randomized controlled trial

1 reference

https://pubmed.ncbi.nlm.nih.gov/29874132

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Frailty and the role of inflammation, immunosenescence and cellular ageing in the very old: cross-sectional findings from the Newcastle 85+ Study.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29874132

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Telomere dysfunction induced by chemotherapeutic agents and radiation in normal human cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29874132

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Association of shorter leukocyte telomere repeat length with dementia and mortality

1 reference

https://pubmed.ncbi.nlm.nih.gov/29874132

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Recurrent somatic TET2 mutations in normal elderly individuals with clonal hematopoiesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/29874132

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Assessment of potential bias from non-participation in a dynamic clinical cohort of long-term childhood cancer survivors: results from the St. Jude Lifetime Cohort Study

1 reference

https://pubmed.ncbi.nlm.nih.gov/29874132

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effect of chemotherapy on telomere dynamics: clinical results and possible mechanisms.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29874132

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A systematic review of leukocyte telomere length and age in adults

1 reference

https://pubmed.ncbi.nlm.nih.gov/29874132

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cellular senescence and the senescent secretory phenotype: therapeutic opportunities

1 reference

https://pubmed.ncbi.nlm.nih.gov/29874132

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Telomeres shorten at equivalent rates in somatic tissues of adults

1 reference

https://pubmed.ncbi.nlm.nih.gov/29874132

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inflammatory markers and incident frailty in men and women: the English Longitudinal Study of Ageing

1 reference

https://pubmed.ncbi.nlm.nih.gov/29874132

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Radiation, atherosclerotic risk factors, and stroke risk in survivors of pediatric cancer: a report from the Childhood Cancer Survivor Study

1 reference

https://pubmed.ncbi.nlm.nih.gov/29874132

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The hallmarks of aging

1 reference

https://pubmed.ncbi.nlm.nih.gov/29874132

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clinical ascertainment of health outcomes among adults treated for childhood cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/29874132

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Independent and combined effects of physical activity and weight loss on inflammatory biomarkers in overweight and obese older adults

1 reference

https://pubmed.ncbi.nlm.nih.gov/29874132

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Radiation-induced epigenetic DNA methylation modification of radiation-response pathways

1 reference

https://pubmed.ncbi.nlm.nih.gov/29874132

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Modifiable risk factors and major cardiac events among adult survivors of childhood cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/29874132

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential DNA methylation with age displays both common and dynamic features across human tissues that are influenced by CpG landscape

1 reference

https://pubmed.ncbi.nlm.nih.gov/29874132

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

DNA methylation age of human tissues and cell types

1 reference

https://pubmed.ncbi.nlm.nih.gov/29874132

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A non-genetic, epigenetic-like mechanism of telomere length inheritance?

1 reference

https://pubmed.ncbi.nlm.nih.gov/29874132

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of the senescence marker p16INK4a in skin biopsies of acute lymphoblastic leukemia survivors: a pilot study

1 reference

https://pubmed.ncbi.nlm.nih.gov/29874132

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Physiologic frailty as a sign of accelerated aging among adult survivors of childhood cancer: a report from the St Jude Lifetime cohort study

1 reference

https://pubmed.ncbi.nlm.nih.gov/29874132

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Telomere content and risk of second malignant neoplasm in survivors of childhood cancer: a report from the Childhood Cancer Survivor Study.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29874132

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Association between telomere length and type 2 diabetes mellitus: a meta-analysis

1 reference

https://pubmed.ncbi.nlm.nih.gov/29874132

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Plasma protein biomarkers of the geriatric syndrome of frailty

1 reference

https://pubmed.ncbi.nlm.nih.gov/29874132

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of extracellular signal-regulated kinase 5 in adipocyte signaling

1 reference

https://pubmed.ncbi.nlm.nih.gov/29874132

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Understanding how we age: insights into inflammaging

1 reference

https://pubmed.ncbi.nlm.nih.gov/29874132

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The relationship between inflammatory biomarkers and telomere length in an occupational prospective cohort study

1 reference

https://pubmed.ncbi.nlm.nih.gov/29874132

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The association between global DNA methylation and telomere length in a longitudinal study of boilermakers

1 reference

https://pubmed.ncbi.nlm.nih.gov/29874132

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Exercise training in childhood cancer survivors with subclinical cardiomyopathy who were treated with anthracyclines

1 reference

https://pubmed.ncbi.nlm.nih.gov/29874132

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Aging and risk of severe, disabling, life-threatening, and fatal events in the childhood cancer survivor study

1 reference

https://pubmed.ncbi.nlm.nih.gov/29874132

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Epigenomic profiling of young and aged HSCs reveals concerted changes during aging that reinforce self-renewal

1 reference

https://pubmed.ncbi.nlm.nih.gov/29874132

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cellular senescence and the senescent secretory phenotype in age-related chronic diseases

1 reference

https://pubmed.ncbi.nlm.nih.gov/29874132

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Feasibility and initial effectiveness of home exercise during maintenance therapy for childhood acute lymphoblastic leukemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/29874132

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Leucocyte telomere length and risk of cardiovascular disease: systematic review and meta-analysis

1 reference

https://pubmed.ncbi.nlm.nih.gov/29874132

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mitochondrial function and mitochondrial DNA maintenance with advancing age.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29874132

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Growth hormone action predicts age-related white adipose tissue dysfunction and senescent cell burden in mice.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29874132

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lifestyle and metabolic syndrome in adult survivors of childhood cancer: a report from the St. Jude Lifetime Cohort Study

1 reference

https://pubmed.ncbi.nlm.nih.gov/29874132

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cancer survivors' uptake and adherence in diet and exercise intervention trials: an integrative data analysis

1 reference

https://pubmed.ncbi.nlm.nih.gov/29874132

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Telomere length is associated with decline in grip strength in older persons aged 65 years and over

1 reference

https://pubmed.ncbi.nlm.nih.gov/29874132

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Somatic mutations, genome mosaicism, cancer and aging

1 reference

https://pubmed.ncbi.nlm.nih.gov/29874132

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Age-related clonal hematopoiesis associated with adverse outcomes

1 reference

https://pubmed.ncbi.nlm.nih.gov/29874132

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clonal hematopoiesis and blood-cancer risk inferred from blood DNA sequence

1 reference

https://pubmed.ncbi.nlm.nih.gov/29874132

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tissue-specific mtDNA abundance from exome data and its correlation with mitochondrial transcription, mass and respiratory activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/29874132

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clinical strategies and animal models for developing senolytic agents

1 reference

https://pubmed.ncbi.nlm.nih.gov/29874132

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Frailty in childhood cancer survivors

1 reference

https://pubmed.ncbi.nlm.nih.gov/29874132

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Function and information content of DNA methylation

1 reference

https://pubmed.ncbi.nlm.nih.gov/29874132

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

DNA methylation age of blood predicts all-cause mortality in later life

1 reference

https://pubmed.ncbi.nlm.nih.gov/29874132

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Systemic inflammation predicts all-cause mortality: a glasgow inflammation outcome study.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29874132

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Achilles' heel of senescent cells: from transcriptome to senolytic drugs.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29874132

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Exercise and inflammation-related epigenetic modifications: focus on DNA methylation

1 reference

https://pubmed.ncbi.nlm.nih.gov/29874132

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Peripheral blood leukocyte telomere length and mortality among 64,637 individuals from the general population

1 reference

https://pubmed.ncbi.nlm.nih.gov/29874132

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Association of proinflammatory cytokines and chemotherapy-associated cognitive impairment in breast cancer patients: a multi-centered, prospective, cohort study

1 reference

https://pubmed.ncbi.nlm.nih.gov/29874132

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of physical activity in telomere length: Systematic review and meta-analysis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29874132

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanisms linking mtDNA damage and aging.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29874132

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Blood-borne biomarkers of mortality risk: systematic review of cohort studies

1 reference

https://pubmed.ncbi.nlm.nih.gov/29874132

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Leukocyte telomere length and mortality in the National Health and Nutrition Examination Survey, 1999-2002

1 reference

https://pubmed.ncbi.nlm.nih.gov/29874132

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cardiorespiratory Capacity and Leukocyte Telomere Length Among Adults in the United States.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29874132

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of a 6-Month, Group-Based, Therapeutic Exercise Program for Childhood Cancer Outpatients on Motor Performance, Level of Activity, and Quality of Life

1 reference

https://pubmed.ncbi.nlm.nih.gov/29874132

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Proinflammatory genotype is associated with the frailty phenotype in the English Longitudinal Study of Ageing

1 reference

https://pubmed.ncbi.nlm.nih.gov/29874132

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Epigenetic regulation of ageing: linking environmental inputs to genomic stability

1 reference

https://pubmed.ncbi.nlm.nih.gov/29874132

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Benefits of Regular Exercise on Inflammatory and Cardiovascular Risk Markers in Normal Weight, Overweight and Obese Adults

1 reference

https://pubmed.ncbi.nlm.nih.gov/29874132

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

JAK inhibition alleviates the cellular senescence-associated secretory phenotype and frailty in old age.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29874132

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Leukocyte telomere length is related to appendicular lean mass: cross-sectional data from the Berlin Aging Study II (BASE-II).

1 reference

https://pubmed.ncbi.nlm.nih.gov/29874132

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Targeting senescent cells enhances adipogenesis and metabolic function in old age

1 reference

https://pubmed.ncbi.nlm.nih.gov/29874132

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of a novel senolytic agent, navitoclax, targeting the Bcl-2 family of anti-apoptotic factors

1 reference

https://pubmed.ncbi.nlm.nih.gov/29874132

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Autophagy maintains stemness by preventing senescence

1 reference

https://pubmed.ncbi.nlm.nih.gov/29874132

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

PGC-1α overexpression via local transfection attenuates mitophagy pathway in muscle disuse atrophy

1 reference

https://pubmed.ncbi.nlm.nih.gov/29874132

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human telomere biology: A contributory and interactive factor in aging, disease risks, and protection

1 reference

https://pubmed.ncbi.nlm.nih.gov/29874132

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mitochondrial Quality Control and Muscle Mass Maintenance

1 reference

https://pubmed.ncbi.nlm.nih.gov/29874132

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Metabolism. AMP-activated protein kinase mediates mitochondrial fission in response to energy stress

1 reference

https://pubmed.ncbi.nlm.nih.gov/29874132

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chronic senolytic treatment alleviates established vasomotor dysfunction in aged or atherosclerotic mice.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29874132

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mitochondrial DNA copy number variation across human cancers

1 reference

https://pubmed.ncbi.nlm.nih.gov/29874132

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The ageing neuromuscular system and sarcopenia: a mitochondrial perspective.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29874132

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mitochondria and Cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/29874132

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Exercise Prevents Diet-Induced Cellular Senescence in Adipose Tissue.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29874132

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Modifiable Factors Associated With Aging Phenotypes Among Adult Survivors of Childhood Acute Lymphoblastic Leukemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/29874132

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Muscle biopsies from human muscle diseases with myopathic pathology reveal common alterations in mitochondrial function

1 reference

https://pubmed.ncbi.nlm.nih.gov/29874132

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Risk of Cataract among Survivors of Childhood and Adolescent Cancer: A Report from the Childhood Cancer Survivor Study

1 reference

https://pubmed.ncbi.nlm.nih.gov/29874132

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Physical exercise training interventions for children and young adults during and after treatment for childhood cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/29874132

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sex-specific effects of cytotoxic chemotherapy agents cyclophosphamide and mitomycin C on gene expression, oxidative DNA damage, and epigenetic alterations in the prefrontal cortex and hippocampus - an aging connection

1 reference

https://pubmed.ncbi.nlm.nih.gov/29874132

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mitochondrial DNA triplication and punctual mutations in patients with mitochondrial neuromuscular disorders

1 reference

https://pubmed.ncbi.nlm.nih.gov/29874132

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Directed elimination of senescent cells by inhibition of BCL-W and BCL-XL

1 reference

https://pubmed.ncbi.nlm.nih.gov/29874132

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interleukin-6 and C-reactive protein, successful aging, and mortality: the PolSenior study

1 reference

https://pubmed.ncbi.nlm.nih.gov/29874132

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of Senescent Cells in the Bone Microenvironment

1 reference

https://pubmed.ncbi.nlm.nih.gov/29874132

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Endocrine Abnormalities in Aging Survivors of Childhood Cancer: A Report From the Childhood Cancer Survivor Study

1 reference

https://pubmed.ncbi.nlm.nih.gov/29874132

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transplanted Senescent Cells Induce an Osteoarthritis-Like Condition in Mice.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29874132

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inflammation and frailty in the elderly: A systematic review and meta-analysis

1 reference

https://pubmed.ncbi.nlm.nih.gov/29874132

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tissue-specific mutation accumulation in human adult stem cells during life

1 reference

https://pubmed.ncbi.nlm.nih.gov/29874132

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Frailty has a stronger association with inflammation than age in older veterans

1 reference

https://pubmed.ncbi.nlm.nih.gov/29874132

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Relationship of systemic cytokine concentrations to cognitive function over two years in women with early stage breast cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/29874132

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inflammatory Cytokines and Comorbidity Development in Breast Cancer Survivors Versus Noncancer Controls: Evidence for Accelerated Aging?

1 reference

https://pubmed.ncbi.nlm.nih.gov/29874132

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evaluation of resistance training to improve muscular strength and body composition in cancer patients undergoing neoadjuvant and adjuvant therapy: a meta-analysis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29874132

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interventions to prevent or reduce the level of frailty in community-dwelling older adults: a scoping review of the literature and international policies

1 reference

https://pubmed.ncbi.nlm.nih.gov/29874132

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clinical and biological markers of premature aging after autologous SCT in childhood cancer.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29874132

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cellular senescence mediates fibrotic pulmonary disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/29874132

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Temporal Trends in Treatment and Subsequent Neoplasm Risk Among 5-Year Survivors of Childhood Cancer, 1970-2015.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29874132

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of Resistance Training and Protein Supplementation in Breast Cancer Survivors

1 reference

https://pubmed.ncbi.nlm.nih.gov/29874132

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

New agents that target senescent cells: the flavone, fisetin, and the BCL-XL inhibitors, A1331852 and A1155463

1 reference

https://pubmed.ncbi.nlm.nih.gov/29874132

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clonal haematopoiesis is not prevalent in survivors of childhood cancer.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29874132

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cellular Senescence: A Translational Perspective

1 reference

https://pubmed.ncbi.nlm.nih.gov/29874132

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

DNA methylation of a novel PAK4 locus influences ototoxicity susceptibility following cisplatin and radiation therapy for pediatric embryonal tumors.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29874132

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Frailty and quality of life in adult survivors of childhood cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/29874132

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Impact of sleep, fatigue, and systemic inflammation on neurocognitive and behavioral outcomes in long-term survivors of childhood acute lymphoblastic leukemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/29874132

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cellular senescence drives age-dependent hepatic steatosis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29874132

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Associations between Global DNA Methylation and Telomere Length in Healthy Adolescents

1 reference

https://pubmed.ncbi.nlm.nih.gov/29874132

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Young adult survivors of childhood acute lymphoblastic leukemia show evidence of chronic inflammation and cellular aging.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29874132

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cellular senescence biomarker p16INK4a+ cell burden in thigh adipose is associated with poor physical function in older women.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29874132

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Senolytic drugs target alveolar epithelial cell function and attenuate experimental lung fibrosis ex vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/29874132

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Targeting cellular senescence prevents age-related bone loss in mice.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29874132

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of HSP90 inhibitors as a novel class of senolytics.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29874132

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The cumulative burden of surviving childhood cancer: an initial report from the St Jude Lifetime Cohort Study (SJLIFE).

1 reference

https://pubmed.ncbi.nlm.nih.gov/29874132

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1200/JCO.2017.76.7467

1 reference

Europe PubMed Central

PMC publication ID

1 July 2019

http://europepmc.org/abstract/PMC/6553838

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

1 July 2019

http://europepmc.org/abstract/PMC/6553838

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

1 July 2019

http://europepmc.org/abstract/PMC/6553838

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