(Q74200562)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10951578%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

title

The contribution of the RING finger domain of MDM2 to cell cycle progression (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10951578%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10951578%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

author name string

M Argentini

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10951578%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

N Barboule

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10951578%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

language of work or name

English

0 references

publication date

1 August 2000

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10951578%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10951578%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

volume

19

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10951578%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

issue

34

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10951578%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

page(s)

3849-3857

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10951578%20AND%20SRC:MED&resulttype=core&format=json

https://scigraph.springernature.com/pub.10.1038/sj.onc.1203737

9 November 2019

exact match

0 references

cites work

MDM2 overexpression generates a skin phenotype in both wild type and p53 null mice.

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7 January 2021

mdm2 expression is induced by wild type p53 activity

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7 January 2021

The proliferation of normal human fibroblasts is dependent upon negative regulation of p53 function by mdm2.

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7 January 2021

The p53-associated protein MDM2 contains a newly characterized zinc-binding domain called the RING finger

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7 January 2021

The solution structure of the RING finger domain from the acute promyelocytic leukaemia proto-oncoprotein PML

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7 January 2021

The RING finger domain: a recent example of a sequence-structure family

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7 January 2021

Design of a synthetic Mdm2-binding mini protein that activates the p53 response in vivo.

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7 January 2021

The human oncoprotein MDM2 arrests the cell cycle: elimination of its cell-cycle-inhibitory function induces tumorigenesis

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7 January 2021

Induction of the growth inhibitor IGF-binding protein 3 by p53

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7 January 2021

Abnormal expression of MDM-2 in breast carcinomas

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7 January 2021

p53-dependent apoptosis in the absence of transcriptional activation of p53-target genes

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7 January 2021

Molecular analysis and chromosomal mapping of amplified genes isolated from a transformed mouse 3T3 cell line

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7 January 2021

High-efficiency transformation of mammalian cells by plasmid DNA

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7 January 2021

Mapping of the p53 and mdm-2 interaction domains

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7 January 2021

mdm-2 inhibits the G1 arrest and apoptosis functions of the p53 tumor suppressor protein

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7 January 2021

Ubiquitous induction of p53 in tumor cells by antisense inhibition of MDM2 expression.

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7 January 2021

WAF1, a potential mediator of p53 tumor suppression

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7 January 2021

The MDM2 oncoprotein binds specifically to RNA through its RING finger domain

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7 January 2021

Mdm2 is a RING finger-dependent ubiquitin protein ligase for itself and p53

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7 January 2021

The mdm-2 oncogene can overcome wild-type p53 suppression of transformed cell growth

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7 January 2021

A genetic approach to mapping the p53 binding site in the MDM2 protein

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7 January 2021

p300/MDM2 complexes participate in MDM2-mediated p53 degradation

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7 January 2021

Mdm2 promotes the rapid degradation of p53

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7 January 2021

Oncoprotein MDM2 is a ubiquitin ligase E3 for tumor suppressor p53

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7 January 2021

Association of p19(ARF) with Mdm2 inhibits ubiquitin ligase activity of Mdm2 for tumor suppressor p53.

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7 January 2021

Activity of MDM2, a ubiquitin ligase, toward p53 or itself is dependent on the RING finger domain of the ligase

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7 January 2021

RB regulates the stability and the apoptotic function of p53 via MDM2

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7 January 2021

Siah-1 N-terminal RING domain is required for proteolysis function, and C-terminal sequences regulate oligomerization and binding to target proteins

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7 January 2021

The tyrosine kinase negative regulator c-Cbl as a RING-type, E2-dependent ubiquitin-protein ligase

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7 January 2021

Expression of transcription factor E2F1 induces quiescent cells to enter S phase

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7 January 2021

Overexpression of Mdm2 in mice reveals a p53-independent role for Mdm2 in tumorigenesis

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7 January 2021

Rescue of embryonic lethality in Mdm2-deficient mice by absence of p53

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7 January 2021

A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia-telangiectasia

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7 January 2021

Regulation of p53 stability by Mdm2

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7 January 2021

Metal and RNA binding properties of the hdm2 RING finger domain

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7 January 2021

An inhibitor of nuclear export activates the p53 response and induces the localization of HDM2 and p53 to U1A-positive nuclear bodies associated with the PODs

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7 January 2021

The MDM2 C-terminal region binds to TAFII250 and is required for MDM2 regulation of the cyclin A promoter

1 reference

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7 January 2021

p53, the cellular gatekeeper for growth and division

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203737

7 January 2021

Identification of a cryptic nucleolar-localization signal in MDM2

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7 January 2021

RING fingers mediate ubiquitin-conjugating enzyme (E2)-dependent ubiquitination

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7 January 2021

Human TAFII31 protein is a transcriptional coactivator of the p53 protein

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7 January 2021

Targeted expression of MDM2 uncouples S phase from mitosis and inhibits mammary gland development independent of p53.

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7 January 2021

Stimulation of E2F1/DP1 transcriptional activity by MDM2 oncoprotein

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7 January 2021

Tumor suppressor p53 is a direct transcriptional activator of the human bax gene

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7 January 2021

The mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation

1 reference

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7 January 2021

Rescue of early embryonic lethality in mdm2-deficient mice by deletion of p53

1 reference

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7 January 2021

Amplification of a gene encoding a p53-associated protein in human sarcomas

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203737

7 January 2021

Oncoprotein MDM2 conceals the activation domain of tumour suppressor p53

1 reference

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7 January 2021

Wild-type human p53 and a temperature-sensitive mutant induce Fas/APO-1 expression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203737

7 January 2021

A model for p53-induced apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203737

7 January 2021

Nucleo-cytoplasmic shuttling of the hdm2 oncoprotein regulates the levels of the p53 protein via a pathway used by the human immunodeficiency virus rev protein.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203737

7 January 2021

Stabilization of the MDM2 oncoprotein by interaction with the structurally related MDMX protein

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203737

7 January 2021

Tumor surveillance via the ARF-p53 pathway.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203737

7 January 2021

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203737

1 reference

7 January 2021

MDM2 interacts with MDMX through their RING finger domains

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203737

7 January 2021

p53 transcriptional activation mediated by coactivators TAFII40 and TAFII60

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203737

7 January 2021

Ubiquitin-dependent c-Jun degradation in vivo is mediated by the delta domain

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203737

7 January 2021

p53 mediated death of cells overexpressing MDM2 by an inhibitor of MDM2 interaction with p53.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203737

7 January 2021

Cooperative signals governing ARF-mdm2 interaction and nucleolar localization of the complex.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203737

7 January 2021

Nucleolar Arf sequesters Mdm2 and activates p53

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203737

7 January 2021

The p53-mdm-2 autoregulatory feedback loop

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203737

7 January 2021

Interaction between the retinoblastoma protein and the oncoprotein MDM2

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203737

7 January 2021

Mutations in human ARF exon 2 disrupt its nucleolar localization and impair its ability to block nuclear export of MDM2 and p53

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203737

7 January 2021

Inhibition of cell proliferation by p107, a relative of the retinoblastoma protein

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203737

7 January 2021