(Q26827066)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24409201%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

title

Targeting heat shock proteins to modulate α-synuclein toxicity (English)

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24409201%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

1 reference

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24409201%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

author name string

Daryl Rhys Jones

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24409201%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

Pamela McLean

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24409201%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

language of work or name

1 reference

1 January 2014

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24409201%20AND%20SRC:MED&resulttype=core&format=json

Therapeutic advances in neurological disorders

4 March 2020

published in

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24409201%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

volume

7

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24409201%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

issue

1

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24409201%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

page(s)

33-51

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24409201%20AND%20SRC:MED&resulttype=core&format=json

Parkinson's Disease: Genetics and Pathogenesis

4 March 2020

cites work

1 reference

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Chaperone proteostasis in Parkinson's disease: stabilization of the Hsp70/alpha-synuclein complex by Hip

7 April 2017

1 reference

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Multicenter analysis of glucocerebrosidase mutations in Parkinson's disease.

7 April 2017

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7 April 2017

1 reference

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CHIP protects from the neurotoxicity of expanded and wild-type ataxin-1 and promotes their ubiquitination and degradation

7 April 2017

1 reference

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Hsp70 chaperones: cellular functions and molecular mechanism

7 April 2017

1 reference

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The blood-brain barrier: bottleneck in brain drug development

7 April 2017

1 reference

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The molecular chaperone Hsp90 plays a role in the assembly and maintenance of the 26S proteasome

7 April 2017

1 reference

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Heat shock protein 90 modulates the unfolded protein response by stabilizing IRE1alpha

7 April 2017

1 reference

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The ubiquitin-proteasome proteolytic pathway: destruction for the sake of construction

7 April 2017

1 reference

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The structural basis of protein folding and its links with human disease

7 April 2017

1 reference

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Identification of CHIP, a novel tetratricopeptide repeat-containing protein that interacts with heat shock proteins and negatively regulates chaperone functions

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3886379

Synphilin-1 associates with alpha-synuclein and promotes the formation of cytosolic inclusions

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3886379

alpha-Synuclein in filamentous inclusions of Lewy bodies from Parkinson's disease and dementia with lewy bodies

7 April 2017

1 reference

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Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism

7 April 2017

1 reference

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Molecular cloning of cDNA encoding an unrecognized component of amyloid in Alzheimer disease

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3886379

Inhibition of heat shock protein HSP90-pp60v-src heteroprotein complex formation by benzoquinone ansamycins: essential role for stress proteins in oncogenic transformation

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3886379

Atomic View of a Toxic Amyloid Small Oligomer

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3886379

Signal integration in the endoplasmic reticulum unfolded protein response

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3886379

alpha-Synuclein locus triplication causes Parkinson's disease

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3886379

Alpha-synuclein in Lewy bodies

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3886379

Mutation in the alpha-synuclein gene identified in families with Parkinson's disease

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3886379

Hsp104, Hsp70, and Hsp40: a novel chaperone system that rescues previously aggregated proteins

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3886379

Repression of heat shock transcription factor HSF1 activation by HSP90 (HSP90 complex) that forms a stress-sensitive complex with HSF1

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3886379

Molecular chaperones in the cytosol: from nascent chain to folded protein

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3886379

CHIP is a U-box-dependent E3 ubiquitin ligase: identification of Hsc70 as a target for ubiquitylation

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3886379

The cerebral proteopathies: neurodegenerative disorders of protein conformation and assembly

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3886379

alpha-Synuclein shares physical and functional homology with 14-3-3 proteins

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3886379

Translation initiator EIF4G1 mutations in familial Parkinson disease

7 April 2017

1 reference

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7 April 2017

1 reference

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FBXO7 mutations cause autosomal recessive, early-onset parkinsonian-pyramidal syndrome

7 April 2017

1 reference

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Lewy body-like pathology in long-term embryonic nigral transplants in Parkinson's disease

7 April 2017

1 reference

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Purine-scaffold Hsp90 inhibitors

7 April 2017

1 reference

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Chronic Parkinsonism in humans due to a product of meperidine-analog synthesis

7 April 2017

1 reference

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Principles that govern the folding of protein chains

7 April 2017

1 reference

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alpha-Synuclein produces a long-lasting increase in neurotransmitter release

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3886379

Synaptic vesicle depletion correlates with attenuated synaptic responses to prolonged repetitive stimulation in mice lacking alpha-synuclein

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3886379

Alpha-synuclein cooperates with CSPalpha in preventing neurodegeneration

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3886379

Heat shock protein 70 inhibits alpha-synuclein fibril formation via preferential binding to prefibrillar species

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3886379

Mice lacking alpha-synuclein display functional deficits in the nigrostriatal dopamine system

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3886379

The new mutation, E46K, of alpha-synuclein causes Parkinson and Lewy body dementia

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3886379

Parkinson's disease: mechanisms and models

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3886379

Ala30Pro mutation in the gene encoding alpha-synuclein in Parkinson's disease

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3886379

Alpha-synuclein locus duplication as a cause of familial Parkinson's disease

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3886379

A Drosophila model of Parkinson's disease

7 April 2017

1 reference

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Stabilization of alpha-synuclein secondary structure upon binding to synthetic membranes

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3886379

Identification of the cystic fibrosis gene: chromosome walking and jumping

7 April 2017

1 reference

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Global brain delivery of neprilysin gene by intravascular administration of AAV vector in mice

25 May 2017

1 reference

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Alpha-synuclein p.H50Q, a novel pathogenic mutation for Parkinson's disease.

28 September 2017

1 reference

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α-Synucleinopathy associated with G51D SNCA mutation: a link between Parkinson's disease and multiple system atrophy?

28 September 2017

1 reference

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Glucose regulated protein 78 diminishes α-synuclein neurotoxicity in a rat model of Parkinson disease.

28 September 2017

1 reference

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SIRT1 protects against α-synuclein aggregation by activating molecular chaperones

28 September 2017

1 reference

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Soluble Aβ oligomer production and toxicity

28 September 2017

1 reference

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Immune responses to AAV in clinical trials

28 September 2017

1 reference

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Ubiquitinylation of α-synuclein by carboxyl terminus Hsp70-interacting protein (CHIP) is regulated by Bcl-2-associated athanogene 5 (BAG5).

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3886379

In vivo demonstration that alpha-synuclein oligomers are toxic

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3886379

Therapeutic options for continuous dopaminergic stimulation in Parkinson's disease

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3886379

Molecular chaperones as rational drug targets for Parkinson's disease therapeutics

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3886379

Heat-shock protein 70 modulates toxic extracellular α-synuclein oligomers and rescues trans-synaptic toxicity

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3886379

Acetylation of tau inhibits its degradation and contributes to tauopathy

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3886379

Stable alpha-synuclein oligomers strongly inhibit chaperone activity of the Hsp70 system by weak interactions with J-domain co-chaperones

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3886379

Cholinergic mesencephalic neurons are involved in gait and postural disorders in Parkinson disease

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3886379

Brain-permeable small-molecule inhibitors of Hsp90 prevent alpha-synuclein oligomer formation and rescue alpha-synuclein-induced toxicity

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3886379

Study of 1,4-dihydropyridine structural scaffold: discovery of novel sirtuin activators and inhibitors

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3886379

Stress-inducible regulation of heat shock factor 1 by the deacetylase SIRT1

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3886379

Rab11a and HSP90 regulate recycling of extracellular alpha-synuclein

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3886379

Current approaches to the treatment of Parkinson's disease

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3886379

SNX-2112, a selective Hsp90 inhibitor, potently inhibits tumor cell growth, angiogenesis, and osteoclastogenesis in multiple myeloma and other hematologic tumors by abrogating signaling via Akt and ERK

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3886379

CHIP targets toxic alpha-Synuclein oligomers for degradation

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3886379

Accumulation and clearance of alpha-synuclein aggregates demonstrated by time-lapse imaging

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3886379

Parkinson's disease--Part 2: Treatment of motor symptoms.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3886379

The two faces of protein misfolding: gain- and loss-of-function in neurodegenerative diseases

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3886379

Tat-Hsp70 protects dopaminergic neurons in midbrain cultures and in the substantia nigra in models of Parkinson's disease.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3886379

SNX2112, a synthetic heat shock protein 90 inhibitor, has potent antitumor activity against HER kinase-dependent cancers

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3886379

Neuroinflammation in Alzheimer's disease and Parkinson's disease: are microglia pathogenic in either disorder?

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3886379

The mechanism of Hsp70 chaperones: (entropic) pulling the models together

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3886379

Soluble protein oligomers as emerging toxins in Alzheimer's and other amyloid diseases.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3886379

Are heat shock proteins therapeutic target for Parkinson's disease?

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3886379

Alleviating neurodegeneration by an anticancer agent: an Hsp90 inhibitor (17-AAG).

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3886379

Small heat shock proteins protect against alpha-synuclein-induced toxicity and aggregation

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3886379

Toxicity mediated by soluble oligomers of beta-amyloid(1-42) on cholinergic SN56.B5.G4 cells

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3886379

Intracellular and extracellular functions of heat shock proteins: repercussions in cancer therapy.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3886379

Divergent roles of IRE1alpha and PERK in the unfolded protein response

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3886379

Intravesicular localization and exocytosis of alpha-synuclein and its aggregates.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3886379

Hsp90 inhibitor geldanamycin and its derivatives as novel cancer chemotherapeutic agents

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3886379

The co-chaperone carboxyl terminus of Hsp70-interacting protein (CHIP) mediates alpha-synuclein degradation decisions between proteasomal and lysosomal pathways

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3886379

Structure and dynamics of micelle-bound human alpha-synuclein

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3886379

A single amino acid substitution differentiates Hsp70-dependent effects on alpha-synuclein degradation and toxicity

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3886379

Geldanamycin induces Hsp70 and prevents alpha-synuclein aggregation and toxicity in vitro

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3886379

Experimental investigation of protein folding and misfolding

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3886379

Mechanism of substrate recognition by Hsp70 chaperones.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3886379

Hsp70 Reduces alpha-Synuclein Aggregation and Toxicity

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3886379

HSP27 but not HSP70 has a potent protective effect against alpha-synuclein-induced cell death in mammalian neuronal cells.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3886379

Quality control in the endoplasmic reticulum protein factory

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3886379

Analysis of heat-shock protein�70 gene polymorphisms and the risk of Parkinson?s disease

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3886379

TorsinA and heat shock proteins act as molecular chaperones: suppression of alpha-synuclein aggregation

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3886379

Alpha-synuclein, especially the Parkinson's disease-associated mutants, forms pore-like annular and tubular protofibrils

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3886379

DeltaF508-CFTR causes constitutive NF-kappaB activation through an ER-overload response in cystic fibrosis lungs

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3886379

Cellular defenses against unfolded proteins: a cell biologist thinks about neurodegenerative diseases

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3886379

Folding of a nascent peptide on the ribosome

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3886379

Mitochondrial dysfunction in Parkinson's disease.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3886379

Heat shock factors and the control of the stress response

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3886379

The cellular response to protein misfolding in the endoplasmic reticulum.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3886379

Polyglutamine-expanded androgen receptors form aggregates that sequester heat shock proteins, proteasome components and SRC-1, and are suppressed by the HDJ-2 chaperone

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3886379

Contig map of the Parkinson's disease region on 4q21-q23.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3886379

DnaJ-like proteins: molecular chaperones and specific regulators of Hsp70.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3886379

Protein synthesis in salivary glands of Drosophila melanogaster: relation to chromosome puffs

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3886379

Heat shock, stress proteins, chaperones, and proteotoxicity

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3886379

Heat shock protein 27 prevents cellular polyglutamine toxicity and suppresses the increase of reactive oxygen species caused by huntingtin

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3886379

A hydrophobic stretch of 12 amino acid residues in the middle of alpha-synuclein is essential for filament assembly.

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3886379

Induction of a heat shock factor 1-dependent stress response alters the cytotoxic activity of hsp90-binding agents.

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3886379

Filamentous alpha-synuclein inclusions link multiple system atrophy with Parkinson's disease and dementia with Lewy bodies.

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3886379

Nigral and cortical Lewy bodies and dystrophic nigral neurites in Parkinson's disease and cortical Lewy body disease contain alpha-synuclein immunoreactivity.

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3886379

CHIP overexpression reduces mutant androgen receptor protein and ameliorates phenotypes of the spinal and bulbar muscular atrophy transgenic mouse model.

31 May 2018

1 reference

https://api.crossref.org/works/10.1177%2F1756285613493469

Chaperone suppression of alpha-synuclein toxicity in a Drosophila model for Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1756285613493469

Mechanisms of Suppression of {alpha}-Synuclein Neurotoxicity by Geldanamycin in Drosophila.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1756285613493469

Inhibition of α-synuclein aggregation by small heat shock proteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1756285613493469

Mechanisms of chaperone suppression of polyglutamine disease: selectivity, synergy and modulation of protein solubility in Drosophila.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1756285613493469

Celastrol protects against MPTP- and 3-nitropropionic acid-induced neurotoxicity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1756285613493469

Chaperone suppression of aggregation and altered subcellular proteasome localization imply protein misfolding in SCA1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1756285613493469

Hsp70 gene transfer by adeno-associated virus inhibits MPTP-induced nigrostriatal degeneration in the mouse model of Parkinson disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1756285613493469

Heat shock prevents alpha-synuclein-induced apoptosis in a yeast model of Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1756285613493469

Progressive decrease in chaperone protein levels in a mouse model of Huntington's disease and induction of stress proteins as a therapeutic approach

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1756285613493469

Permeabilization of lipid bilayers is a common conformation-dependent activity of soluble amyloid oligomers in protein misfolding diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1756285613493469

Cotranslational folding of proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1756285613493469

Morphogenesis of Lewy bodies: dissimilar incorporation of alpha-synuclein, ubiquitin, and p62.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1756285613493469

A novel progranulin mutation associated with variable clinical presentation and tau, TDP43 and alpha-synuclein pathology.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1756285613493469

Characterization of Lewy body pathology in 12- and 16-year-old intrastriatal mesencephalic grafts surviving in a patient with Parkinson's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1756285613493469

Alpha-synuclein-enhanced green fluorescent protein fusion proteins form proteasome sensitive inclusions in primary neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1756285613493469

CHIP suppresses polyglutamine aggregation and toxicity in vitro and in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1756285613493469

Heat shock protects PC12 cells against MPP+ toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1756285613493469

A new puffing pattern induced by temperature shock and DNP in drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1756285613493469

Geldanamycin induces heat shock protein 70 and protects against MPTP-induced dopaminergic neurotoxicity in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1756285613493469

Hsp104 catalyzes formation and elimination of self-replicating Sup35 prion conformers

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1756285613493469

Geldanamycin activates a heat shock response and inhibits huntingtin aggregation in a cell culture model of Huntington's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1756285613493469

Aggregated and monomeric alpha-synuclein bind to the S6' proteasomal protein and inhibit proteasomal function

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1756285613493469

Induction of heat shock protein 70 reduces the alteration of striatal electrical activity caused by mitochondrial impairment.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1756285613493469

Vesicle permeabilization by protofibrillar alpha-synuclein: implications for the pathogenesis and treatment of Parkinson's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1756285613493469

Suppression of polyglutamine-mediated neurodegeneration in Drosophila by the molecular chaperone HSP70.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1756285613493469

Role of alpha-synuclein in presynaptic dopamine recruitment.

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1756285613493469

Monoclonal antibodies inhibit prion replication and delay the development of prion disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F1756285613493469

Heat shock proteins reduce alpha-synuclein aggregation induced by MPP+ in SK-N-SH cells

21 January 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/24409201

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Young onset Parkinson's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/24409201

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

A highly sensitive protein-protein interaction assay based on Gaussia luciferase

1 reference

https://pubmed.ncbi.nlm.nih.gov/24409201

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1177/1756285613493469

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24409201%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24409201%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24409201%20AND%20SRC:MED&resulttype=core&format=json