(Q35777630)

10 August 2017

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title

HIF1 and oxygen sensing in the brain (English)

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10 August 2017

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Myriam Bernaudin

2

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author name string

Frank R Sharp

series ordinal

1

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10 August 2017

language of work or name

English

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publication date

1 June 2004

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Nature Reviews Neuroscience

10 August 2017

published in

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10 August 2017

volume

5

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10 August 2017

issue

6

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10 August 2017

page(s)

437-448

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https://scigraph.springernature.com/pub.10.1038/nrn1408

10 August 2017

exact match

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cites work

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The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis

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Cobalt inhibits the interaction between hypoxia-inducible factor-alpha and von Hippel-Lindau protein by direct binding to hypoxia-inducible factor-alpha

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Regulation and destabilization of HIF-1alpha by ARD1-mediated acetylation

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Hsp90 regulates a von Hippel Lindau-independent hypoxia-inducible factor-1 alpha-degradative pathway

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21 January 2018

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21 January 2018

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Erythropoietin crosses the blood-brain barrier to protect against experimental brain injury

21 January 2018

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21 January 2018

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21 January 2018

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Hypoxia induces phosphorylation of the cyclic AMP response element-binding protein by a novel signaling mechanism

21 January 2018

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Egr-1 and Sp1 interact functionally with the 5-lipoxygenase promoter and its naturally occurring mutants

21 January 2018

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Evidence for a protective role of metallothionein-1 in focal cerebral ischemia

21 January 2018

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Synergistic cooperation between hypoxia and transforming growth factor-beta pathways on human vascular endothelial growth factor gene expression

21 January 2018

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Analysis of the promoter region of the human VEGF-related factor gene

21 January 2018

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21 January 2018

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Blood genomic expression profile for neuronal injury

21 January 2018

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Hypoxia-induced mitochondrial and nuclear DNA damage in the rat brain.

21 January 2018

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21 January 2018

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Multiple organ pathology, metabolic abnormalities and impaired homeostasis of reactive oxygen species in Epas1-/- mice

21 January 2018

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Is HIF-1alpha a pro- or an anti-apoptotic protein?

21 January 2018

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Identification of a novel mutation in Cu/Zn superoxide dismutase gene associated with familial amyotrophic lateral sclerosis

21 January 2018

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Deletion of the hypoxia-response element in the vascular endothelial growth factor promoter causes motor neuron degeneration.

21 January 2018

1 reference

VEGF is increased in serum but not in spinal cord from patients with amyotrophic lateral sclerosis.

21 January 2018

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The von Hippel-Lindau tumor suppressor protein

21 January 2018

1 reference

Suppression of tumor growth through disruption of hypoxia-inducible transcription

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Expression of hypoxia-inducible factor 1alpha in tumours of patients with glioblastoma

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1 reference

Role of vascular endothelial growth factor in physiologic and pathologic angiogenesis: therapeutic implications

21 January 2018

1 reference

Stabilization of wild-type p53 by hypoxia-inducible factor 1alpha

21 January 2018

1 reference

Hypoxia-inducible factor-2alpha (HIF-2alpha) is involved in the apoptotic response to hypoglycemia but not to hypoxia

21 January 2018

1 reference

Role of HIF-1alpha in hypoxia-mediated apoptosis, cell proliferation and tumour angiogenesis

21 January 2018

1 reference

Hypoxia-inducible factor 1alpha is essential for cell cycle arrest during hypoxia

21 January 2018

1 reference

Hypoxic Regulation of Lactate Dehydrogenase A

21 January 2018

1 reference

New insights into an enigmatic tumour suppressor

21 January 2018

1 reference

Identification of an oxygen responsive enhancer element in the glyceraldehyde-3-phosphate dehydrogenase gene

21 January 2018

1 reference

Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension

21 January 2018

1 reference

The role of the aryl hydrocarbon receptor nuclear translocator (ARNT) in hypoxic induction of gene expression. Studies in ARNT-deficient cells

31 March 2020

1 reference

Hypoxia-inducible factor 1 levels vary exponentially over a physiologically relevant range of O2 tension

31 March 2020

1 reference

Endothelial PAS domain protein 1 (EPAS1), a transcription factor selectively expressed in endothelial cells

31 March 2020

1 reference

Cellular and developmental control of O2 homeostasis by hypoxia-inducible factor 1 alpha

31 March 2020

1 reference

The hypoxia-responsive transcription factor EPAS1 is essential for catecholamine homeostasis and protection against heart failure during embryonic development

31 March 2020

1 reference

Widespread hypoxia-inducible expression of HIF-2alpha in distinct cell populations of different organs.

31 March 2020

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Expression of hypoxia-inducible factor-1alpha in the brain of rats during chronic hypoxia

31 March 2020

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Impaired physiological responses to chronic hypoxia in mice partially deficient for hypoxia-inducible factor 1alpha

31 March 2020

1 reference

Hypoxia and mitochondrial inhibitors regulate expression of glucose transporter-1 via distinct Cis-acting sequences

31 March 2020

1 reference

Transferrin receptor induction by hypoxia. HIF-1-mediated transcriptional activation and cell-specific post-transcriptional regulation

31 March 2020

1 reference

Functional role of p35srj, a novel p300/CBP binding protein, during transactivation by HIF-1

31 March 2020

1 reference

Hypoxia-inducible Factor-1 Mediates Transcriptional Activation of the Heme Oxygenase-1 Gene in Response to Hypoxia

31 March 2020

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31 March 2020

1 reference

Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation

31 March 2020

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Binding of the von Hippel-Lindau tumor suppressor protein to Elongin B and C

31 March 2020

1 reference

HIFalpha targeted for VHL-mediated destruction by proline hydroxylation: implications for O2 sensing

31 March 2020

1 reference

Mammalian EGLN genes have distinct patterns of mRNA expression and regulation

31 March 2020

1 reference

The role of mitochondria in the regulation of hypoxia-inducible factor 1 expression during hypoxia

31 March 2020

1 reference

Role of hypoxia-inducible factor-1 in hypoxia-induced ischemic tolerance in neonatal rat brain

31 March 2020

1 reference

Insulin-like growth factor 1 induces hypoxia-inducible factor 1-mediated vascular endothelial growth factor expression, which is dependent on MAP kinase and phosphatidylinositol 3-kinase signaling in colon cancer cells

31 March 2020

1 reference

Activation of hypoxia-inducible factor-1 in the rat cerebral cortex after transient global ischemia: potential role of insulin-like growth factor-1

31 March 2020

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Endogenous 2-oxoacids differentially regulate expression of oxygen sensors

31 March 2020

1 reference

Inducible nitric oxide synthase gene expression in brain following cerebral ischemia

31 March 2020

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Discovery of adrenomedullin in rat ischemic cortex and evidence for its role in exacerbating focal brain ischemic damage

31 March 2020

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Dual role of nitric oxide in focal cerebral ischemia

31 March 2020

1 reference

Angiogenic role of adrenomedullin through activation of Akt, mitogen-activated protein kinase, and focal adhesion kinase in endothelial cells

31 March 2020

1 reference

Expression of vascular endothelial growth factor (VEGF) and its receptors (Flt-1 and Flk-1) following permanent and transient occlusion of the middle cerebral artery in the rat.

31 March 2020

1 reference

Role of angiogenesis in patients with cerebral ischemic stroke

31 March 2020

1 reference

Hypoxia-inducible nuclear factors bind to an enhancer element located 3' to the human erythropoietin gene

31 March 2020

1 reference

Hypoxia Response Elements in the Aldolase A, Enolase 1, and Lactate Dehydrogenase A Gene Promoters Contain Essential Binding Sites for Hypoxia-inducible Factor 1

31 March 2020

1 reference

Differential changes of bax, caspase-3 and p21 mRNA expression after transient focal brain ischemia in the rat

31 March 2020

1 reference

Hypoxic preconditioning of ischaemic myocardium

31 March 2020

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Hypoxic preconditioning and hypoxic-ischemic brain damage in the immature rat: pathologic and metabolic correlates.

31 March 2020

1 reference

Neuroprotection by hypoxic preconditioning requires sequential activation of vascular endothelial growth factor receptor and Akt.

31 March 2020

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Erythropoietin therapy for acute stroke is both safe and beneficial

31 March 2020

1 reference

Herpes simplex virus vectors overexpressing the glucose transporter gene protect against seizure-induced neuron loss

31 March 2020

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Protection from oxidative stress-induced apoptosis in cortical neuronal cultures by iron chelators is associated with enhanced DNA binding of hypoxia-inducible factor-1 and ATF-1/CREB and increased expression of glycolytic enzymes, [...]

31 March 2020

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Activation of the nuclear factor-kappaB is a key event in brain tolerance.

31 March 2020

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31 March 2020

Hypoxia versus ischemia.

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Invited review: Adaptive responses of skeletal muscle to intermittent hypoxia: the known and the unknown

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The management of retinopathy of prematurity

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Mutations in all five exons ofSOD-1 may cause ALS

31 March 2020

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Regulation of gene expression for tyrosine hydroxylase in oxygen sensitive cells by hypoxia

31 March 2020

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von Hippel-Lindau disease

31 March 2020

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Hypoxia-inducible factor-1alpha mediates hypoxia-induced delayed neuronal death that involves p53.

31 March 2020

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Oxygen and ion concentrations in normoxic and hypoxic brain cells.

31 March 2020

1 reference

7 January 2021

Induction of the Plasminogen Activator Inhibitor-1 Gene Expression by Mild Hypoxia Via a Hypoxia Response Element Binding the Hypoxia-Inducible Factor-1 in Rat Hepatocytes

1 reference

7 January 2021

Transforming growth factor-beta1 as a regulator of the serpins/t-PA axis in cerebral ischemia

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7 January 2021

MKP-1 as a target for pharmacological manipulations in PC12 cell survival

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7 January 2021

Identifiers

DOI

10.1038/NRN1408

1 reference

10 August 2017

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