(Q35944680)

11 August 2017

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title

Early events in the DNA damage response (English)

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11 August 2017

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Irene Ward

1

1 reference

PubMed ID

15536012

11 August 2017

Junjie Chen

series ordinal

2

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11 August 2017

1 January 2004

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Current Topics in Developmental Biology

11 August 2017

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11 August 2017

63

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11 August 2017

1-35

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Cell cycle checkpoint signaling through the ATM and ATR kinases

11 August 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

Questioning the role of checkpoint kinase 2 in the p53 DNA damage response

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

Mrc1 transduces signals of DNA replication stress to activate Rad53.

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

Rad54 protein possesses chromatin-remodeling activity stimulated by the Rad51-ssDNA nucleoprotein filament

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

Impaired p53-mediated DNA damage response, cell-cycle disturbance and chromosome aberrations in Nijmegen breakage syndrome lymphoblastoid cell lines.

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

Enhanced phosphorylation of p53 by ATM in response to DNA damage

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

Atm-deficient mice: a paradigm of ataxia telangiectasia

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

ATR kinase activity regulates the intranuclear translocation of ATR and RPA following ionizing radiation

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

Mammalian G1- and S-phase checkpoints in response to DNA damage

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

Increased ionizing radiation sensitivity and genomic instability in the absence of histone H2AX

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

Histone H2AX: a dosage-dependent suppressor of oncogenic translocations and tumors

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

Human Rad51 protein promotes ATP-dependent homologous pairing and strand transfer reactions in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

Role of the human RAD51 protein in homologous recombination and double-stranded-break repair

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

Heterozygous germ line hCHK2 mutations in Li-Fraumeni syndrome

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

Synergistic actions of Rad51 and Rad52 in recombination and DNA repair.

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

Components of the Ku-dependent non-homologous end-joining pathway are involved in telomeric length maintenance and telomeric silencing

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

Essential and dispensable roles of ATR in cell cycle arrest and genome maintenance

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

ATM phosphorylates histone H2AX in response to DNA double-strand breaks

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

Retention of the human Rad9 checkpoint complex in extraction-resistant nuclear complexes after DNA damage

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

Reconstitution and molecular analysis of the hRad9-hHus1-hRad1 (9-1-1) DNA damage responsive checkpoint complex

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

Chk2 activation dependence on Nbs1 after DNA damage

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

From BRCA1 to RAP1: a widespread BRCT module closely associated with DNA repair

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

Activation of the ATM kinase by ionizing radiation and phosphorylation of p53

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

The hMre11/hRad50 protein complex and Nijmegen breakage syndrome: linkage of double-strand break repair to the cellular DNA damage response

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

The Mre11 complex is required for ATM activation and the G2/M checkpoint

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

H2AX haploinsufficiency modifies genomic stability and tumor susceptibility

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

Histone H2AX phosphorylation is dispensable for the initial recognition of DNA breaks

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

Genomic instability in mice lacking histone H2AX

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

Autophosphorylation of the DNA-dependent protein kinase catalytic subunit is required for rejoining of DNA double-strand breaks

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

Lack of correlation between ATM protein expression and tumour cell radiosensitivity

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

The DNA-dependent protein kinase is inactivated by autophosphorylation of the catalytic subunit

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

Stable interaction between the products of the BRCA1 and BRCA2 tumor suppressor genes in mitotic and meiotic cells

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

Accurate in vitro end joining of a DNA double strand break with partially cohesive 3'-overhangs and 3'-phosphoglycolate termini: effect of Ku on repair fidelity

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

Human claspin is required for replication checkpoint control

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

Nucleotide excision repair "a legacy of creativity".

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

Overexpression of a kinase-inactive ATR protein causes sensitivity to DNA-damaging agents and defects in cell cycle checkpoints

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

ATR and ATRIP: partners in checkpoint signaling

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

Requirement of ATM-dependent phosphorylation of brca1 in the DNA damage response to double-strand breaks

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

Mre11 protein complex prevents double-strand break accumulation during chromosomal DNA replication.

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

Reconstitution of an ATM-dependent checkpoint that inhibits chromosomal DNA replication following DNA damage.

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

The Mre11 complex: at the crossroads of dna repair and checkpoint signalling

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

The Fanconi anaemia/BRCA pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

Synapsis of DNA ends by DNA-dependent protein kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

Human Rad50/Mre11 is a flexible complex that can tether DNA ends

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

Mice lacking p21CIP1/WAF1 undergo normal development, but are defective in G1 checkpoint control

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

Evidence for replicative repair of DNA double-strand breaks leading to oncogenic translocation and gene amplification

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

53BP1 functions in an ATM-dependent checkpoint pathway that is constitutively activated in human cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

The Nijmegen breakage syndrome protein is essential for Mre11 phosphorylation upon DNA damage

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

Identification of in vitro and in vivo phosphorylation sites in the catalytic subunit of the DNA-dependent protein kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

A role for Saccharomyces cerevisiae histone H2A in DNA repair.

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

Serine15 phosphorylation stimulates p53 transactivation but does not directly influence interaction with HDM2.

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

Pleiotropic defects in ataxia-telangiectasia protein-deficient mice

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

MEC1-dependent phosphorylation of Rad9p in response to DNA damage

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

Homologous and non-homologous recombination differentially affect DNA damage repair in mice

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

The ATM-Chk2-Cdc25A checkpoint pathway guards against radioresistant DNA synthesis

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

The DNA damage-dependent intra-S phase checkpoint is regulated by parallel pathways

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

DNA damage-induced G2-M checkpoint activation by histone H2AX and 53BP1

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

H2AX is required for chromatin remodeling and inactivation of sex chromosomes in male mouse meiosis

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

Interaction of the Fanconi anemia proteins and BRCA1 in a common pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

Ataxia-telangiectasia-mutated (ATM) and NBS1-dependent phosphorylation of Chk1 on Ser-317 in response to ionizing radiation

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

ATM-dependent phosphorylation of nibrin in response to radiation exposure

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

The pathogenesis of ataxia-telangiectasia. Learning from a Rosetta Stone

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

V(D)J recombination gets a break

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

Budding yeast Rad9 is an ATP-dependent Rad53 activating machine.

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

Nbs1 promotes ATM dependent phosphorylation events including those required for G1/S arrest

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

MDC1 is required for the intra-S-phase DNA damage checkpoint

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

Sloppier copier DNA polymerases involved in genome repair

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

Rejoining of DNA double-strand breaks in vitro by single-strand annealing.

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

The DNA-dependent protein kinase: requirement for DNA ends and association with Ku antigen

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

The Werner syndrome protein is a DNA helicase

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

Accessibility and structural role of histone domains in chromatin. biophysical and immunochemical studies of progressive digestion with immobilized proteases

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

The RING heterodimer BRCA1-BARD1 is a ubiquitin ligase inactivated by a breast cancer-derived mutation

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

An ATR- and Chk1-dependent S checkpoint inhibits replicon initiation following UVC-induced DNA damage

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

Pathways for mitotic homologous recombination in mammalian cells

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

The ABCs of SMC proteins: two-armed ATPases for chromosome condensation, cohesion, and repair

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

DNA damage-induced activation of p53 by the checkpoint kinase Chk2

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

Molecular mechanism of class switch recombination: linkage with somatic hypermutation

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

Structural biochemistry and interaction architecture of the DNA double-strand break repair Mre11 nuclease and Rad50-ATPase

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

Biallelic inactivation of BRCA2 in Fanconi anemia

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

Reconstitution of the mammalian DNA double-strand break end-joining reaction reveals a requirement for an Mre11/Rad50/NBS1-containing fraction

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

Two cellular proteins that bind to wild-type but not mutant p53

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

Stimulation of p53-mediated transcriptional activation by the p53-binding proteins, 53BP1 and 53BP2

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

Sister chromatid gene conversion is a prominent double-strand break repair pathway in mammalian cells

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

Nijmegen breakage syndrome cells fail to induce the p53-mediated DNA damage response following exposure to ionizing radiation

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

Checkpoint activation regulates mutagenic translesion synthesis

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

Histone deacetylase 4 interacts with 53BP1 to mediate the DNA damage response

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

Werner protein is a target of DNA-dependent protein kinase in vivo and in vitro, and its catalytic activities are regulated by phosphorylation

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia-telangiectasia

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

ATM associates with and phosphorylates p53: mapping the region of interaction

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

Substrate specificities and identification of putative substrates of ATM kinase family members

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

Involvement of the cohesin protein, Smc1, in Atm-dependent and independent responses to DNA damage

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

NBS1 localizes to gamma-H2AX foci through interaction with the FHA/BRCT domain

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

BRCA1 protein products ... Functional motifs...

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

Molecular mimicry connects BRCA2 to Rad51 and recombinational DNA repair

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

ATP activates ataxia-telangiectasia mutated (ATM) in vitro. Importance of autophosphorylation

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

Claspin, a novel protein required for the activation of Chk1 during a DNA replication checkpoint response in Xenopus egg extracts

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

Radiation down-regulates replication origin activity throughout the S phase in mammalian cells

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

Claspin, a Chk1-regulatory protein, monitors DNA replication on chromatin independently of RPA, ATR, and Rad17.

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

Evidence for DNA-PK-dependent and -independent DNA double-strand break repair pathways in mammalian cells as a function of the cell cycle

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

Displacement of DNA-PKcs from DNA ends by the Werner syndrome protein

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

Homology-directed repair is a major double-strand break repair pathway in mammalian cells

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

ATM phosphorylates p95/nbs1 in an S-phase checkpoint pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

Model for Homologous Recombination During Transfer of DNA into Mouse L Cells: Role for DNA Ends in the Recombination Process

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

Purification and characterization of human DNA damage checkpoint Rad complexes

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

Mediator of DNA damage checkpoint protein 1 regulates BRCA1 localization and phosphorylation in DNA damage checkpoint control

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

MDC1 is coupled to activated CHK2 in mammalian DNA damage response pathways

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

Distinct spatiotemporal dynamics of mammalian checkpoint regulators induced by DNA damage

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

Disruption of mRad50 causes embryonic stem cell lethality, abnormal embryonic development, and sensitivity to ionizing radiation

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

A requirement for replication in activation of the ATR-dependent DNA damage checkpoint

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

Hairpin opening and overhang processing by an Artemis/DNA-dependent protein kinase complex in nonhomologous end joining and V(D)J recombination

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

Recombinational DNA double-strand breaks in mice precede synapsis

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

BRCT domain-containing protein TopBP1 functions in DNA replication and damage response

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

Mechanism and control of class-switch recombination

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

BRCT Repeats As Phosphopeptide-Binding Modules Involved in Protein Targeting

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

Mre11 complex and DNA replication: linkage to E2F and sites of DNA synthesis

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

Ataxia telangiectasia-mutated phosphorylates Chk2 in vivo and in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

Radiation induction of p53 in cells from Nijmegen breakage syndrome is defective but not similar to ataxia-telangiectasia

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

ATM-dependent phosphorylation of Mdm2 on serine 395: role in p53 activation by DNA damage

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

Reconstitution of the strand invasion step of double-strand break repair using human Rad51 Rad52 and RPA proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

Threonine 68 is required for radiation-induced phosphorylation and activation of Cds1.

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

Base excision repair in yeast and mammals

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

The DNA-dependent protein kinase interacts with DNA to form a protein-DNA complex that is disrupted by phosphorylation

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

DNA damage-dependent nuclear dynamics of the Mre11 complex

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

The Bloom's and Werner's syndrome proteins are DNA structure-specific helicases

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

Brca1 controls homology-directed DNA repair

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

BRCA2 is required for homology-directed repair of chromosomal breaks

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

In situ visualization of DNA double-strand break repair in human fibroblasts

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

A splicing mutation affecting expression of ataxia-telangiectasia and Rad3-related protein (ATR) results in Seckel syndrome

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

Mrc1 is a replication fork component whose phosphorylation in response to DNA replication stress activates Rad53.

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

Radiosensitivity in ataxia-telangiectasia: a new explanation

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

Cut5 Is Required for the Binding of Atr and DNA Polymerase α to Genotoxin-damaged Chromatin

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

A critical role for histone H2AX in recruitment of repair factors to nuclear foci after DNA damage

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

Insights into DNA recombination from the structure of a RAD51-BRCA2 complex

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

NFBD1, like 53BP1, is an early and redundant transducer mediating Chk2 phosphorylation in response to DNA damage

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

Mitotic and G2 checkpoint control: regulation of 14-3-3 protein binding by phosphorylation of Cdc25C on serine-216

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

Mechanisms of DNA double-strand break repair and their potential to induce chromosomal aberrations

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

BRCA2 keeps Rad51 in line. High-fidelity homologous recombination prevents breast and ovarian cancer?

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

Tumor suppressor p53 binding protein 1 (53BP1) is involved in DNA damage-signaling pathways

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

H2AX is required for recombination between immunoglobulin switch regions but not for intra-switch region recombination or somatic hypermutation

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

Phosphopeptide Binding Specificities of BRCA1 COOH-terminal (BRCT) Domains

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

Megabase chromatin domains involved in DNA double-strand breaks in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

Leaky Scid phenotype associated with defective V(D)J coding end processing in Artemis-deficient mice

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

Homologous recombination resolution defect in werner syndrome

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

Conservation of the Chk1 checkpoint pathway in mammals: linkage of DNA damage to Cdk regulation through Cdc25

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

Evidence for simultaneous protein interactions between human Rad51 paralogs

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

DNA mismatch repair: molecular mechanisms and biological function

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

p53 binding protein 1 (53BP1) is an early participant in the cellular response to DNA double-strand breaks

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

Rad9 phosphorylation sites couple Rad53 to the Saccharomyces cerevisiae DNA damage checkpoint

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

Association of BRCA1 with Rad51 in mitotic and meiotic cells

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

NFBD1, a novel nuclear protein with signature motifs of FHA and BRCT, and an internal 41-amino acid repeat sequence, is an early participant in DNA damage response

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

Werner syndrome protein. I. DNA helicase and dna exonuclease reside on the same polypeptide.

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

Cloning of human, mouse and fission yeast recombination genes homologous to RAD51 and recA

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

Mediator function of the human Rad51B-Rad51C complex in Rad51/RPA-catalyzed DNA strand exchange

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

Ctf7p is essential for sister chromatid cohesion and links mitotic chromosome structure to the DNA replication machinery

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

Purification and DNA binding properties of the ataxia-telangiectasia gene product ATM.

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

The two faces of BRCA2, a FANCtastic discovery

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

The DNA double-strand break repair gene hMRE11 is mutated in individuals with an ataxia-telangiectasia-like disorder

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

MDC1 is a mediator of the mammalian DNA damage checkpoint

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

Double-strand breaks at an initiation site for meiotic gene conversion

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

Rad53 FHA domain associated with phosphorylated Rad9 in the DNA damage checkpoint

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

Low levels of endogenous oxidative damage cluster levels in unirradiated viral and human DNAs

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

Recruitment of ATM protein to double strand DNA irradiated with ionizing radiation

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

Homologous recombination and non-homologous end-joining pathways of DNA double-strand break repair have overlapping roles in the maintenance of chromosomal integrity in vertebrate cells

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

Mrc1 channels the DNA replication arrest signal to checkpoint kinase Cds1.

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

Repair of ionizing radiation damage in mammalian cells. Alternative pathways and their fidelity

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

Homologous recombinational repair of DNA ensures mammalian chromosome stability

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

Recombinational DNA repair and human disease

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

A role for ATR in the DNA damage-induced phosphorylation of p53

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

Functional interactions between BRCA1 and the checkpoint kinase ATR during genotoxic stress

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

Preferential binding of ATR protein to UV-damaged DNA.

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

Requirement of the MRN complex for ATM activation by DNA damage

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

The MRN complex: coordinating and mediating the response to broken chromosomes

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

The budding yeast Rad9 checkpoint protein is subjected to Mec1/Tel1-dependent hyperphosphorylation and interacts with Rad53 after DNA damage

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

Structure of the Ku heterodimer bound to DNA and its implications for double-strand break repair

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

The catalytic subunit of DNA-dependent protein kinase selectively regulates p53-dependent apoptosis but not cell-cycle arrest

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

Histone H2AX is phosphorylated in an ATR-dependent manner in response to replicational stress

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

Accumulation of Checkpoint Protein 53BP1 at DNA Breaks Involves Its Binding to Phosphorylated Histone H2AX

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

p53 Binding protein 53BP1 is required for DNA damage responses and tumor suppression in mice

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

53BP1 is required for class switch recombination

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

The RAD9 gene controls the cell cycle response to DNA damage in Saccharomyces cerevisiae

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

Hus1 acts upstream of chk1 in a mammalian DNA damage response pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

DNA damage-induced apoptosis requires the DNA-dependent protein kinase, and is mediated by the latent population of p53.

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

Potential role for the BLM helicase in recombinational repair via a conserved interaction with RAD51

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

ATM phosphorylation of Nijmegen breakage syndrome protein is required in a DNA damage response

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

Negative cell cycle regulation and DNA damage-inducible phosphorylation of the BRCT protein 53BP1.

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

Conditional gene targeted deletion by Cre recombinase demonstrates the requirement for the double-strand break repair Mre11 protein in murine embryonic stem cells

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

Two molecularly distinct G(2)/M checkpoints are induced by ionizing irradiation

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

NFBD1/MDC1 regulates ionizing radiation-induced focus formation by DNA checkpoint signaling and repair factors

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

BRCA2 function in DNA binding and recombination from a BRCA2-DSS1-ssDNA structure

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

BRCA1 regulates the G2/M checkpoint by activating Chk1 kinase upon DNA damage

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

SMC1 is a downstream effector in the ATM/NBS1 branch of the human S-phase checkpoint

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

Geometry of a complex formed by double strand break repair proteins at a single DNA end: recruitment of DNA-PKcs induces inward translocation of Ku protein

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

The role of single-stranded DNA and polymerase alpha in establishing the ATR, Hus1 DNA replication checkpoint

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

Positional cloning of the Werner's syndrome gene

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

The BRCT Domain Is a Phospho-Protein Binding Domain

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

Chk2 phosphorylation of BRCA1 regulates DNA double-strand break repair

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

Functional link between ataxia-telangiectasia and Nijmegen breakage syndrome gene products

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

Unrepaired DNA breaks in p53-deficient cells lead to oncogenic gene amplification subsequent to translocations.

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

Targeted disruption of the Nijmegen breakage syndrome gene NBS1 leads to early embryonic lethality in mice.

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

Regulation of ATR substrate selection by Rad17-dependent loading of Rad9 complexes onto chromatin

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

Sensing DNA damage through ATRIP recognition of RPA-ssDNA complexes

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

A DNA damage response pathway controlled by Tel1 and the Mre11 complex

1 reference

https://api.crossref.org/works/10.1016%2FS0070-2153%2804%2963001-8

7 January 2021

10.1016/S0070-2153(04)63001-8

Identifiers

DOI

1 reference

release_m5tdohiq5nhj5jef2lcrvmur7q

11 August 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/m5tdohiq5nhj5jef2lcrvmur7q

24 November 2022

mapped directly with Wikidata item

PubMed ID

15536012

1 reference

PubMed ID

15536012