(Q36921742)

17 August 2017

1 reference

title

Focal adhesion kinase and p53 signaling in cancer cells (English)

1 reference

17 August 2017

Vita M Golubovskaya

1

1 reference

PubMed ID

17725966

17 August 2017

William G Cance

series ordinal

2

1 reference

PubMed ID

17725966

17 August 2017

language of work or name

1 reference

1 January 2007

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International Review of Cytology

17 August 2017

1 reference

17 August 2017

263

1 reference

17 August 2017

103-153

1 reference

Treatment of ischemic brain damage by perturbing NMDA receptor- PSD-95 protein interactions

17 August 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

Vascular endothelial growth factor stimulates tyrosine phosphorylation and recruitment to new focal adhesions of focal adhesion kinase and paxillin in endothelial cells

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

Src mediates stimulation by vascular endothelial growth factor of the phosphorylation of focal adhesion kinase at tyrosine 861, and migration and anti-apoptosis in endothelial cells

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

Increased dosage and amplification of the focal adhesion kinase gene in human cancer cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

Focal adhesion kinase (p125FAK) expression correlates with motility of human melanoma cell lines

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

Targeting the receptor-Gq interface to inhibit in vivo pressure overload myocardial hypertrophy

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

Affinity-driven peptide selection of an NFAT inhibitor more selective than cyclosporin A.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

The structural basis of localization and signaling by the focal adhesion targeting domain

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

Expression of focal adhesion kinase and phosphorylated focal adhesion kinase in squamous cell carcinoma of the larynx

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

Vascular endothelial growth factor regulates focal adhesion assembly in human brain microvascular endothelial cells through activation of the focal adhesion kinase and related adhesion focal tyrosine kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

HIV-1 Tat-mediated effects on focal adhesion assembly and permeability in brain microvascular endothelial cells

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

Identification and characterization of a novel related adhesion focal tyrosine kinase (RAFTK) from megakaryocytes and brain

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

Association of phosphatidylinositol 3-kinase, via the SH2 domains of p85, with focal adhesion kinase in polyoma middle t-transformed fibroblasts.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

FAK signaling is critical for ErbB-2/ErbB-3 receptor cooperation for oncogenic transformation and invasion

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

Transcriptional activation of cyclooxygenase-2 by tumor suppressor p53 requires nuclear factor-kappaB.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

p53 polymorphism influences response in cancer chemotherapy via modulation of p73-dependent apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

Focal adhesion kinase N-terminus in breast carcinoma cells induces rounding, detachment and apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

Key cancer cell signal transduction pathways as therapeutic targets.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

Constitutive and stimulated production of VEGF by human megakaryoblastic cell lines: effect on proliferation and signaling pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

The human GRAF gene is fused to MLL in a unique t(5;11)(q31;q23) and both alleles are disrupted in three cases of myelodysplastic syndrome/acute myeloid leukemia with a deletion 5q

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

Activation of focal adhesion kinase by hepatitis B virus HBx protein: multiple functions in viral replication.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

p53 as a target for anti-cancer drug development.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

Neurofibromin binds to caveolin-1 and regulates ras, FAK, and Akt

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

ASAP1, a phospholipid-dependent arf GTPase-activating protein that associates with and is phosphorylated by Src.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

Cloning of focal adhesion kinase, pp125FAK, from rat brain reveals multiple transcripts with different patterns of expression

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

Alternative spliced transcripts as cancer markers

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

Tyrosine phosphorylation of focal adhesion kinase at sites in the catalytic domain regulates kinase activity: a role for Src family kinases

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

Overexpression of focal adhesion kinase in head and neck squamous cell carcinoma is independent of fak gene copy number.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

Up-regulation of focal adhesion kinase in non-small cell lung cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

Crystal structure of the FERM domain of focal adhesion kinase.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

JSAP1 is required for the cell adhesion and spreading of mouse embryonic fibroblasts.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

Synergistic effect of focal adhesion kinase overexpression and hepatocyte growth factor stimulation on cell transformation

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

Association of focal adhesion kinase with its potential substrate phosphatidylinositol 3-kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

Interaction of focal adhesion kinase with cytoskeletal protein talin

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

Regulation of the PH-domain-containing tyrosine kinase Etk by focal adhesion kinase through the FERM domain

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

Direct interaction of focal adhesion kinase (FAK) with Met is required for FAK to promote hepatocyte growth factor-induced cell invasion

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

Selective killing of transformed cells by cyclin/cyclin-dependent kinase 2 antagonists

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

Direct activation of Bax by p53 mediates mitochondrial membrane permeabilization and apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

Design and synthesis of 7H-pyrrolo[2,3-d]pyrimidines as focal adhesion kinase inhibitors. Part 2

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

Regulation of focal adhesion kinase by its amino-terminal domain through an autoinhibitory interaction

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

Organization and post-transcriptional processing of focal adhesion kinase gene

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

New concepts regarding focal adhesion kinase promotion of cell migration and proliferation

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

Genetic, biochemical and structural approaches to talin function

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

The multidomain protein Trio binds the LAR transmembrane tyrosine phosphatase, contains a protein kinase domain, and has separate rac-specific and rho-specific guanine nucleotide exchange factor domains

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

RNA interference targeting focal adhesion kinase enhances pancreatic adenocarcinoma gemcitabine chemosensitivity

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

Focal adhesion kinase gene silencing promotes anoikis and suppresses metastasis of human pancreatic adenocarcinoma cells

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

The proline-rich region of mouse p53 influences transactivation and apoptosis but is largely dispensable for these functions.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

G protein-coupled receptor activation rapidly stimulates focal adhesion kinase phosphorylation at Ser-843. Mediation by Ca2+, calmodulin, and Ca2+/calmodulin-dependent kinase II.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

Wild-type p53 activates transcription in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

A genetic model for colorectal tumorigenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

Mapping of the focal adhesion kinase (Fadk) gene to mouse chromosome 15 and human chromosome 8.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

Enhanced insulin signaling via Shc in human breast cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

Hepatocyte growth factor/scatter factor stimulates mitogenesis and migration of a head and neck squamous cell carcinoma cell line

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

Control of apoptosis by p53.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

Evidence for a function of death-receptor-related, death-domain-containing proteins in anoikis

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

Integrins and anoikis

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

1 reference

7 January 2021

Control of adhesion-dependent cell survival by focal adhesion kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

Focal adhesion kinase is overexpressed in hepatocellular carcinoma and can be served as an independent prognostic factor.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

Cloning and characterization of Dfak56, a homolog of focal adhesion kinase, in Drosophila melanogaster.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

Interaction of Hic-5, A senescence-related protein, with focal adhesion kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

Clinical significance of focal adhesion kinase in resectable pancreatic cancer.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

FAK regulates biological processes important for the pathogenesis of cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

Identification of FIP200 interaction with the TSC1-TSC2 complex and its role in regulation of cell size control

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

Role of FIP200 in cardiac and liver development and its regulation of TNFalpha and TSC-mTOR signaling pathways

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

Vascular endothelial growth factor receptor-3 and focal adhesion kinase bind and suppress apoptosis in breast cancer cells

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

The complexity of p53 modulation: emerging patterns from divergent signals

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

Nck-2 interacts with focal adhesion kinase and modulates cell motility

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

Dual inhibition of focal adhesion kinase and epidermal growth factor receptor pathways cooperatively induces death receptor-mediated apoptosis in human breast cancer cells

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

Cloning and characterization of the promoter region of human focal adhesion kinase gene: nuclear factor kappa B and p53 binding sites

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

Direct interaction of the N-terminal domain of focal adhesion kinase with the N-terminal transactivation domain of p53

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

FAK phosphorylation sites mapped by mass spectrometry

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

Differential expression of protease activated receptor 1 (Par1) and pY397FAK in benign and malignant human ovarian tissue samples

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

Role of focal adhesion kinase in integrin signaling

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

Association of focal adhesion kinase with Grb7 and its role in cell migration

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

Overexpression of focal adhesion kinase (p125FAK) in human colorectal carcinoma liver metastases: independence from c-src or c-yes activation

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

Focal adhesion kinase is activated in invading fibrosarcoma cells and regulates metastasis

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

Signaling through focal adhesion kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

Focal adhesion protein-tyrosine kinase phosphorylated in response to cell attachment to fibronectin

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

Focal adhesion kinase signaling activities and their implications in the control of cell survival and motility

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

FRNK, the autonomously expressed C-terminal region of focal adhesion kinase, is uniquely regulated in vascular smooth muscle: analysis of expression in transgenic mice

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

The focal adhesion targeting (FAT) region of focal adhesion kinase is a four-helix bundle that binds paxillin

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

Overexpression of FAK promotes Ras activity through the formation of a FAK/p120RasGAP complex in malignant astrocytoma cells

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

Focal adhesion kinase signaling and the aggressive melanoma phenotype.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

Identification of sequences required for the efficient localization of the focal adhesion kinase, pp125FAK, to cellular focal adhesions

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

An SH3 domain-containing GTPase-activating protein for Rho and Cdc42 associates with focal adhesion kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

Transcriptional repression of the anti-apoptotic survivin gene by wild type p53.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

New approaches to understanding p53 gene tumor mutation spectra

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

Bombesin, lysophosphatidic acid, and epidermal growth factor rapidly stimulate focal adhesion kinase phosphorylation at Ser-910: requirement for ERK activation

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

PDGF and FGF induce focal adhesion kinase (FAK) phosphorylation at Ser-910: dissociation from Tyr-397 phosphorylation and requirement for ERK activation

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

Reduced cell motility and enhanced focal adhesion contact formation in cells from FAK-deficient mice

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

Impairment of mobility in endodermal cells by FAK deficiency

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

Extracellular matrix survival signals transduced by focal adhesion kinase suppress p53-mediated apoptosis.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

Role of tyrosine specific phosphorylation of cellular proteins, especially EGF receptor and p125FAK in human lung cancer cells

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

Specific decrease in the level of Hic-5, a focal adhesion protein, during immortalization of mouse embryonic fibroblasts, and its association with focal adhesion kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

FAK phosphorylation at Ser-843 inhibits Tyr-397 phosphorylation, cell spreading and migration.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

Integrin expression on cell adhesion function and up-regulation of P125FAK and paxillin in metastatic renal carcinoma cells

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

Bi-directional regulation between tyrosine kinase Etk/BMX and tumor suppressor p53 in response to DNA damage

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

p53-mediated negative regulation of stathmin/Op18 expression is associated with G(2)/M cell-cycle arrest

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

Nuclear import of N-terminal FAK by activation of the FcepsilonRI receptor in RBL-2H3 cells

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

Adhesion-linked kinases in cancer; emphasis on src, focal adhesion kinase and PI 3-kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

Overexpression of focal adhesion kinase, a protein tyrosine kinase, in ovarian carcinoma.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

PIAS1-mediated sumoylation of focal adhesion kinase activates its autophosphorylation

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

The focal adhesion kinase (P125FAK) is constitutively active in human malignant melanoma

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

Antiapoptotic action of focal adhesion kinase (FAK) against ionizing radiation

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

Rat oligodendroglia express c-met and focal adhesion kinase, protein tyrosine kinases implicated in regulating epithelial cell motility

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

Degradation and dephosphorylation of focal adhesion kinase during okadaic acid-induced apoptosis in human neuroblastoma cells

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

Increased expression of focal adhesion kinase in thyroid cancer: immunohistochemical study

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

Endostatin blocks vascular endothelial growth factor-mediated signaling via direct interaction with KDR/Flk-1.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

Laminin 5 expression protects against anoikis at aerogenous spread and lepidic growth of human lung adenocarcinoma.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

Focal adhesion kinase expression in oral cancers

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

Focal adhesion kinase overexpression induces enhanced pathological retinal angiogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

The tumour suppressor protein p53 can repress transcription of cyclin B.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

Focal adhesion kinase suppresses apoptosis by binding to the death domain of receptor-interacting protein

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

p53 and breast cancer, an update

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

High focal adhesion kinase expression in invasive breast carcinomas is associated with an aggressive phenotype

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

Phosphorylation of focal adhesion kinase (FAK) on Ser732 is induced by rho-dependent kinase and is essential for proline-rich tyrosine kinase-2-mediated phosphorylation of FAK on Tyr407 in response to vascular endothelial growth factor

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

Protein tyrosine kinase PYK2 involved in Ca(2+)-induced regulation of ion channel and MAP kinase functions

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

p53, the cellular gatekeeper for growth and division

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

Upregulation of focal adhesion kinase (FAK) expression in ductal carcinoma in situ (DCIS) is an early event in breast tumorigenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

Tyrosine phosphorylation of type Igamma phosphatidylinositol phosphate kinase by Src regulates an integrin-talin switch

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

Inhibition of Stat1-mediated gene activation by PIAS1

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

The association of ASAP1, an ADP ribosylation factor-GTPase activating protein, with focal adhesion kinase contributes to the process of focal adhesion assembly

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

Focal adhesion kinase overexpression in endometrial neoplasia

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

Nuclear localization and apoptotic regulation of an amino-terminal domain focal adhesion kinase fragment in endothelial cells

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

p53-dependent apoptosis modulates the cytotoxicity of anticancer agents

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

Abrogation of oncogene-associated apoptosis allows transformation of p53-deficient cells

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

Focal adhesion proteins as markers of malignant transformation and prognostic indicators in breast carcinoma

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

Expression of GRP and its receptor in well-differentiated colon cancer cells correlates with the presence of focal adhesion kinase phosphorylated at tyrosines 397 and 407.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

Requirement for focal adhesion kinase in tumor cell adhesion

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

Selective inhibition of NF-kappaB activation by a peptide that blocks the interaction of NEMO with the IkappaB kinase complex

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

Activation of the focal adhesion kinase signal transduction pathway in cervical carcinoma cell lines and human genital epithelial cells immortalized with human papillomavirus type 18

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

The role of focal-adhesion kinase in cancer - a new therapeutic opportunity

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

Signaling between focal adhesion kinase and trio

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

Mechanism of cell cycle regulation by FIP200 in human breast cancer cells

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

Integrin-regulated FAK-Src signaling in normal and cancer cells

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

Intrinsic FAK activity and Y925 phosphorylation facilitate an angiogenic switch in tumors

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

FAK overexpression is correlated with tumour invasiveness and lymph node metastasis in oesophageal squamous cell carcinoma

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

Wild-type p53 negatively regulates the expression of a microtubule-associated protein

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

HEF1 is a necessary and specific downstream effector of FAK that promotes the migration of glioblastoma cells

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

Tyrosine phosphorylation of 100-130 kDa proteins in lung cancer correlates with poor prognosis

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

Structures of the cancer-related Aurora-A, FAK, and EphA2 protein kinases from nanovolume crystallography

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

PTK2 and EIF3S3 genes may be amplification targets at 8q23-q24 and are associated with large hepatocellular carcinomas

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

Integrin signalling: a new Cas(t) of characters enters the stage

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

Decision making by p53: life, death and cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

Induced focal adhesion kinase (FAK) expression in FAK-null cells enhances cell spreading and migration requiring both auto- and activation loop phosphorylation sites and inhibits adhesion-dependent tyrosine phosphorylation of Pyk2.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

Focal adhesion kinase as a marker of invasive potential in differentiated human thyroid cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

Overexpression of the focal adhesion kinase (p125FAK) in the vascular smooth muscle cells of intimal hyperplasia.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

Activated Src increases adhesion, survival and alpha2-integrin expression in human breast cancer cells

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

Focal adhesion kinase: the first ten years

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

Overexpression of focal adhesion kinase in vascular endothelial cells promotes angiogenesis in transgenic mice

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

Targeting the c-Met signaling pathway in cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

Re-expression of the tumor suppressor NF2/merlin inhibits invasiveness in mesothelioma cells and negatively regulates FAK.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

Ezrin interacts with focal adhesion kinase and induces its activation independently of cell-matrix adhesion

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

The focal adhesion targeting domain of focal adhesion kinase contains a hinge region that modulates tyrosine 926 phosphorylation

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

Integrin activation by talin

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

Signaling via Shc family adapter proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

Requirement of phosphatidylinositol 3-kinase in focal adhesion kinase-promoted cell migration

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

Analysis of FAK-associated signaling pathways in the regulation of cell cycle progression

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

Signal transduction through integrins: a central role for focal adhesion kinase?

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

Activation of FAK is necessary for the osteogenic differentiation of human mesenchymal stem cells on laminin-5

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

Focal adhesion kinase signaling pathways regulate the osteogenic differentiation of human mesenchymal stem cells

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

Cloning and characterization of cell adhesion kinase beta, a novel protein-tyrosine kinase of the focal adhesion kinase subfamily

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

Biochemical signals and biological responses elicited by the focal adhesion kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

FAK and paxillin: regulators of N-cadherin adhesion and inhibitors of cell migration?

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

Focal adhesion kinase and associated proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

pp125FAK a structurally distinctive protein-tyrosine kinase associated with focal adhesions

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

Autophosphorylation of the focal adhesion kinase, pp125FAK, directs SH2-dependent binding of pp60src

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

Focal adhesion kinase and paxillin bind to peptides mimicking beta integrin cytoplasmic domains

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

Complex formation with focal adhesion kinase: A mechanism to regulate activity and subcellular localization of Src kinases

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

Evidence for in vivo phosphorylation of the Grb2 SH2-domain binding site on focal adhesion kinase by Src-family protein-tyrosine kinases

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

Multiple connections link FAK to cell motility and invasion

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

Integrin-mediated signal transduction linked to Ras pathway by GRB2 binding to focal adhesion kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

Fibronectin-stimulated signaling from a focal adhesion kinase-c-Src complex: involvement of the Grb2, p130cas, and Nck adaptor proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

Control of motile and invasive cell phenotypes by focal adhesion kinase.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

Members of the PIAS family act as SUMO ligases for c-Jun and p53 and repress p53 activity

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

PIAS/SUMO: new partners in transcriptional regulation.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

High expression of focal adhesion kinase (p125FAK) in node-negative breast cancer is related to overexpression of HER-2/neu and activated Akt kinase but does not predict outcome

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

Elevated focal adhesion kinase expression facilitates oral tumor cell invasion

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

Expression analysis of protein tyrosine kinases of the FAK (focal adhesion kinase) family in osteosarcoma

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

pp125FAK in human melanocytes and melanoma: expression and phosphorylation

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

Association of Grb7 with phosphoinositides and its role in the regulation of cell migration

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

A novel low-molecular weight inhibitor of focal adhesion kinase, TAE226, inhibits glioma growth

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

Clonal expansion of p53 mutant cells is associated with brain tumour progression

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

FAK integrates growth-factor and integrin signals to promote cell migration

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

Effect of focal adhesion kinase (FAK) downregulation with FAK antisense oligonucleotides and 5-fluorouracil on the viability of melanoma cell lines

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

Anti-apoptotic role of focal adhesion kinase (FAK). Induction of inhibitor-of-apoptosis proteins and apoptosis suppression by the overexpression of FAK in a human leukemic cell line, HL-60.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

Biological significance of focal adhesion kinase in ovarian cancer: role in migration and invasion

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

The focal adhesion kinase amino-terminal domain localises to nuclei and intercellular junctions in HEK 293 and MDCK cells independently of tyrosine 397 and the carboxy-terminal domain

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

Vascular endothelial growth factor induces activation and subcellular translocation of focal adhesion kinase (p125FAK) in cultured rat cardiac myocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

A scaffold protein in the c-Jun N-terminal kinase signaling pathway is associated with focal adhesion kinase and tyrosine-phosphorylated

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

JSAP1/JIP3 cooperates with focal adhesion kinase to regulate c-Jun N-terminal kinase and cell migration

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

Inhibition of cell migration, spreading, and focal adhesions by tumor suppressor PTEN

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

PTEN interactions with focal adhesion kinase and suppression of the extracellular matrix-dependent phosphatidylinositol 3-kinase/Akt cell survival pathway

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

Regulation of the G2/M transition by p53.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

RIP death domain structural interactions implicated in TNF-mediated proliferation and survival

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

Focal adhesion kinase expression is not a prognostic predictor in colon adenocarcinoma patients

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

SH2- and SH3-mediated interactions between focal adhesion kinase and Src.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

Focal adhesion kinase is required for the spatial organization of the leading edge in migrating cells

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

Focal adhesion kinase (pp125FAK) expression, activation and association with paxillin and p50CSK in human metastatic prostate carcinoma

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

1 reference

7 January 2021

Suppression of chemically induced apoptosis but not necrosis of renal proximal tubular epithelial (LLC-PK1) cells by focal adhesion kinase (FAK). Role of FAK in maintaining focal adhesion organization after acute renal cell injury

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

Requirement for focal adhesion kinase in the early phase of mammary adenocarcinoma lung metastasis formation

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

Focal adhesion kinase and protein kinase B cooperate to suppress doxorubicin-induced apoptosis of breast tumor cells

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

Requirement of nuclear factor of activated T-cells in calcineurin-mediated cardiomyocyte hypertrophy

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

p53 Activation by small molecules: application in oncology

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

Unbalanced alternative splicing and its significance in cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

Focal adhesion kinase regulates metastatic adhesion of carcinoma cells within liver sinusoids

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

The ins and outs of p53

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

Minimal features of paxillin that are required for the tyrosine phosphorylation of focal adhesion kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

A global map of p53 transcription-factor binding sites in the human genome

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

Expression of focal adhesion kinase gene and invasive cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

Expression of growth factor receptors, the focal adhesion kinase, and other tyrosine kinases in human soft tissue tumors

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

Human T and B lymphocytes express a structurally conserved focal adhesion kinase, pp125FAK.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

The promise and obstacle of p53 as a cancer therapeutic agent

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

Src activation regulates anoikis in human colon tumor cell lines

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

Negative regulation of bcl-2 expression by p53 in hematopoietic cells

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

Serine 732 phosphorylation of FAK by Cdk5 is important for microtubule organization, nuclear movement, and neuronal migration

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

Direct interaction of v-Src with the focal adhesion kinase mediated by the Src SH2 domain

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

The focal adhesion kinase suppresses transformation-associated, anchorage-independent apoptosis in human breast cancer cells. Involvement of death receptor-related signaling pathways.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

Photodynamic therapy suppresses the migration and invasion of head and neck cancer cells in vitro.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

Src SH2 arginine 175 is required for cell motility: specific focal adhesion kinase targeting and focal adhesion assembly function

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

Wild-type p53 induces apoptosis of myeloid leukaemic cells that is inhibited by interleukin-6

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

Structural basis for the binding of proline-rich peptides to SH3 domains

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

Rapid tyrosine phosphorylation of focal adhesion kinase, paxillin, and p130Cas by gastrin in human colon cancer cells

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

Enhanced expression of cholecystokinin-2 receptor promotes the progression of colon cancer through activation of focal adhesion kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

Role of focal adhesion kinase and phosphatidylinositol 3'-kinase in integrin fibronectin receptor-mediated, matrix metalloproteinase-1-dependent invasion by metastatic prostate cancer cells

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

Direct Interaction of Focal Adhesion Kinase with p190RhoGEF

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

Site-specific acetylation by p300 or CREB binding protein regulates erythroid Krüppel-like factor transcriptional activity via its interaction with the SWI-SNF complex

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

Cloning of a Xenopus laevis cDNA encoding focal adhesion kinase (FAK) and expression during early development.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

Squamous cell carcinoma cell aggregates escape suspension-induced, p53-mediated anoikis: fibronectin and integrin alphav mediate survival signals through focal adhesion kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

Adenovirus E1B 55-kilodalton oncoprotein binds to Daxx and eliminates enhancement of p53-dependent transcription by Daxx

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7696%2807%2963003-4

7 January 2021

10.1016/S0074-7696(07)63003-4

Identifiers

DOI

1 reference

17 August 2017

1 reference

PubMed ID

17725966