(Q37603053)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19779493%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

review article

1 reference

title

Escape from p53-mediated tumor surveillance in neuroblastoma: switching off the p14(ARF)-MDM2-p53 axis (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19779493%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

1 reference

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19779493%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

Ali Rihani

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19779493%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

author name string

T Van Maerken

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19779493%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

A De Paepe

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19779493%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

F Speleman

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19779493%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

publication date

25 September 2009

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19779493%20AND%20SRC:MED&resulttype=core&format=json

Cell Death & Differentiation

8 February 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19779493%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

volume

16

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19779493%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

issue

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19779493%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

page(s)

1563-1572

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19779493%20AND%20SRC:MED&resulttype=core&format=json

p53 is nuclear and functional in both undifferentiated and differentiated neuroblastoma

8 February 2020

cites work

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.138

Regulation of p14ARF through subnuclear compartmentalization

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.138

p53 cellular localization and function in neuroblastoma: evidence for defective G(1) arrest despite WAF1 induction in MYCN-amplified cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.138

Neoplastic transformation by the human gene N-myc

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.138

Cytoplasmic sequestration of wild-type p53 protein impairs the G1 checkpoint after DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.138

Mdm2 deficiency suppresses MYCN-Driven neuroblastoma tumorigenesis in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.138

The p53 pathway and its inactivation in neuroblastoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.138

7 January 2021

p53 determines multidrug sensitivity of childhood neuroblastoma

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.138

7 January 2021

Increased frequency of aberrations in the p53/MDM2/p14(ARF) pathway in neuroblastoma cell lines established at relapse

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.138

7 January 2021

Small-molecule MDM2 antagonists as a new therapy concept for neuroblastoma

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.138

7 January 2021

Molecular analysis and chromosomal mapping of amplified genes isolated from a transformed mouse 3T3 cell line

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.138

7 January 2021

Keeping p53 in check: essential and synergistic functions of Mdm2 and Mdm4.

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.138

7 January 2021

Live or let die: the cell's response to p53

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.138

7 January 2021

Oncoprotein MDM2 conceals the activation domain of tumour suppressor p53

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.138

7 January 2021

Repression of p53-mediated transcription by MDM2: a dual mechanism

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.138

7 January 2021

Murine double minute (MDM2) blocks p53-coactivator interaction, a new mechanism for inhibition of p53-dependent gene expression

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.138

7 January 2021

Molecular interaction map of the p53 and Mdm2 logic elements, which control the Off-On switch of p53 in response to DNA damage

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.138

7 January 2021

p53 ubiquitination: Mdm2 and beyond

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.138

7 January 2021

The RING domain of Mdm2 mediates histone ubiquitylation and transcriptional repression.

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.138

7 January 2021

Mdm2-mediated NEDD8 conjugation of p53 inhibits its transcriptional activity

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.138

7 January 2021

MDM2-HDAC1-mediated deacetylation of p53 is required for its degradation

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.138

7 January 2021

Hdm2 recruits a hypoxia-sensitive corepressor to negatively regulate p53-dependent transcription

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.138

7 January 2021

Yin Yang 1 is a negative regulator of p53.

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.138

7 January 2021

MDM2 interaction with nuclear corepressor KAP1 contributes to p53 inactivation

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.138

7 January 2021

Tumor suppression by Ink4a-Arf: progress and puzzles

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.138

7 January 2021

Divorcing ARF and p53: an unsettled case

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.138

7 January 2021

Tumour biology: Policing of oncogene activity by p53

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.138

7 January 2021

The pathological response to DNA damage does not contribute to p53-mediated tumour suppression

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.138

7 January 2021

Association of p19(ARF) with Mdm2 inhibits ubiquitin ligase activity of Mdm2 for tumor suppressor p53.

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.138

7 January 2021

Mutations in human ARF exon 2 disrupt its nucleolar localization and impair its ability to block nuclear export of MDM2 and p53

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.138

7 January 2021

P19(ARF) stabilizes p53 by blocking nucleo-cytoplasmic shuttling of Mdm2

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.138

7 January 2021

Nucleolar Arf sequesters Mdm2 and activates p53

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.138

7 January 2021

An N-terminal p14ARF peptide blocks Mdm2-dependent ubiquitination in vitro and can activate p53 in vivo

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.138

7 January 2021

Oncogenic ras activates the ARF-p53 pathway to suppress epithelial cell transformation

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.138

7 January 2021

Stabilization of p53 by p14ARF without relocation of MDM2 to the nucleolus.

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.138

7 January 2021

Nucleophosmin (B23) targets ARF to nucleoli and inhibits its function

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.138

7 January 2021

ARF-BP1/Mule is a critical mediator of the ARF tumor suppressor

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.138

7 January 2021

p53- and Mdm2-Independent Repression of NF-κB Transactivation by the ARF Tumor Suppressor

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.138

7 January 2021

Cytogenetic evolution of mycn and mdm2 amplification in the neuroblastoma ls tumour and its cell line

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.138

7 January 2021

Identification of two distinct chromosome 12-derived amplification units in neuroblastoma cell line NGP.

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.138

7 January 2021

High-resolution array copy number analyses for detection of deletion, gain, amplification and copy-neutral LOH in primary neuroblastoma tumors: four cases of homozygous deletions of the CDKN2A gene

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.138

7 January 2021

The p16 (CDKN2A) gene is involved in the growth of neuroblastoma cells and its expression is associated with prognosis of neuroblastoma patients

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.138

7 January 2021

A single nucleotide polymorphism in the MDM2 promoter attenuates the p53 tumor suppressor pathway and accelerates tumor formation in humans

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.138

7 January 2021

Impact of a single nucleotide polymorphism in the MDM2 gene on neuroblastoma development and aggressiveness: results of a pilot study on 239 patients

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.138

7 January 2021

Impact of MDM2 SNP309 genotype on progression and survival of stage 4 neuroblastoma

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.138

7 January 2021

Neuroblastoma: biological insights into a clinical enigma

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.138

7 January 2021

Amplification of N-myc in untreated human neuroblastomas correlates with advanced disease stage

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.138

7 January 2021

Association of multiple copies of the N-myc oncogene with rapid progression of neuroblastomas

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.138

7 January 2021

The mycn/max protein complex in neuroblastoma. Short review

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.138

7 January 2021

Human N-myc gene contributes to neoplastic transformation of mammalian cells in culture.

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.138

7 January 2021

Modulation of N-myc expression alters the invasiveness of neuroblastoma

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.138

7 January 2021

Enhanced expression of MYCN leads to centrosome hyperamplification after DNA damage in neuroblastoma cells

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.138

7 January 2021

MYCN-directed centrosome amplification requires MDM2-mediated suppression of p53 activity in neuroblastoma cells

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.138

7 January 2021

Down-regulation of endothelial cell growth inhibitors by enhanced MYCN oncogene expression in human neuroblastoma cells.

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.138

7 January 2021

MYCN oncogene and angiogenesis: down-regulation of endothelial growth inhibitors in human neuroblastoma cells. Purification, structural, and functional characterization

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.138

7 January 2021

Oncogene MYCN regulates localization of NKT cells to the site of disease in neuroblastoma

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.138

7 January 2021

Targeted expression of MYCN causes neuroblastoma in transgenic mice

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.138

7 January 2021

MycN and IFNgamma cooperate in apoptosis of human neuroblastoma cells.

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.138

7 January 2021

MycN sensitizes neuroblastoma cells for drug-induced apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.138

7 January 2021

MycN sensitizes neuroblastoma cells for drug-triggered apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.138

7 January 2021

N-Myc overexpression leads to decreased beta1 integrin expression and increased apoptosis in human neuroblastoma cells

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.138

7 January 2021

The p53 regulatory gene MDM2 is a direct transcriptional target of MYCN in neuroblastoma.

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.138

7 January 2021

Mdm2 haplo-insufficiency profoundly inhibits Myc-induced lymphomagenesis

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.138

7 January 2021

Phosphoregulation of Twist1 provides a mechanism of cell fate control

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.138

7 January 2021

Mutations in TWIST, a basic helix-loop-helix transcription factor, in Saethre-Chotzen syndrome

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.138

7 January 2021

Mutations of the TWIST gene in the Saethre-Chotzen syndrome

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.138

7 January 2021

Oncogenic cooperation between H-Twist and N-Myc overrides failsafe programs in cancer cells.

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.138

7 January 2021

Twist is a potential oncogene that inhibits apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.138

7 January 2021

Regulation of histone acetyltransferases p300 and PCAF by the bHLH protein twist and adenoviral oncoprotein E1A

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.138

7 January 2021

HOXA5-twist interaction alters p53 homeostasis in breast cancer cells

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.138

7 January 2021

Twist and p53 reciprocally regulate target genes via direct interaction

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.138

7 January 2021

Induction of EMT by twist proteins as a collateral effect of tumor-promoting inactivation of premature senescence

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.138

7 January 2021

BMI1 is a target gene of E2F-1 and is strongly expressed in primary neuroblastomas

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.138

7 January 2021

Bmi-1 is essential for the tumorigenicity of neuroblastoma cells

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.138

7 January 2021

Polycomb silencers control cell fate, development and cancer

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.138

7 January 2021

The oncogene and Polycomb-group gene bmi-1 regulates cell proliferation and senescence through the ink4a locus

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.138

7 January 2021

Bmi-1 determines the proliferative capacity of normal and leukaemic stem cells

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.138

7 January 2021

Bmi-1 is required for maintenance of adult self-renewing haematopoietic stem cells

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.138

7 January 2021

Bmi-1 dependence distinguishes neural stem cell self-renewal from progenitor proliferation

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.138

7 January 2021

Bmi-1 promotes neural stem cell self-renewal and neural development but not mouse growth and survival by repressing the p16Ink4a and p19Arf senescence pathways

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.138

7 January 2021

Identification of cooperating oncogenes in E mu-myc transgenic mice by provirus tagging

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.138

7 January 2021

Novel zinc finger gene implicated as myc collaborator by retrovirally accelerated lymphomagenesis in E mu-myc transgenic mice.

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.138

7 January 2021

Perturbation of B and T cell development and predisposition to lymphomagenesis in EμBmi1 transgenic mice require the Bmi1 RING finger

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.138

7 January 2021

Multiple docking sites on substrate proteins form a modular system that mediates recognition by ERK MAP kinase

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.138

7 January 2021

Bmi-1 cooperates with H-Ras to transform human mammary epithelial cells via dysregulation of multiple growth-regulatory pathways.

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.138

7 January 2021

Rb inactivation promotes genomic instability by uncoupling cell cycle progression from mitotic control.

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.138

7 January 2021

E2F proteins regulate MYCN expression in neuroblastomas

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.138

7 January 2021

Bmi-1 regulates the differentiation and clonogenic self-renewal of I-type neuroblastoma cells in a concentration-dependent manner.

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.138

7 January 2021

Definition and characterization of a region of 1p36.3 consistently deleted in neuroblastoma

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.138

7 January 2021

Expression and sequence analysis of candidates for the 1p36.31 tumor suppressor gene deleted in neuroblastomas

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.138

7 January 2021

CHD5, a tumor suppressor gene deleted from 1p36.31 in neuroblastomas

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.138

7 January 2021

CHD5, a new member of the chromodomain gene family, is preferentially expressed in the nervous system

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.138

7 January 2021

CHD5 is a tumor suppressor at human 1p36

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.138

7 January 2021

Gain of chromosome arm 17q and adverse outcome in patients with neuroblastoma

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.138

7 January 2021

Unequivocal delineation of clinicogenetic subgroups and development of a new model for improved outcome prediction in neuroblastoma

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.138

7 January 2021

Oncogenic properties of PPM1D located within a breast cancer amplification epicenter at 17q23

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.138

7 January 2021

Amplification of PPM1D in human tumors abrogates p53 tumor-suppressor activity

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.138

7 January 2021

The serine-threonine protein phosphatase PPM1D is frequently activated through amplification in aggressive primary breast tumours

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.138

7 January 2021

Genomic and protein expression profiling identifies CDK6 as novel independent prognostic marker in medulloblastoma

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.138

7 January 2021

Medulloblastomas overexpress the p53-inactivating oncogene WIP1/PPM1D

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.138

7 January 2021

Wip1, a novel human protein phosphatase that is induced in response to ionizing radiation in a p53-dependent manner

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.138

7 January 2021

p53-inducible wip1 phosphatase mediates a negative feedback regulation of p38 MAPK-p53 signaling in response to UV radiation

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.138

7 January 2021

PPM1D dephosphorylates Chk1 and p53 and abrogates cell cycle checkpoints

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.138

7 January 2021

Regulation of the antioncogenic Chk2 kinase by the oncogenic Wip1 phosphatase

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.138

7 January 2021

Intrinsic kinase activity and SQ/TQ domain of Chk2 kinase as well as N-terminal domain of Wip1 phosphatase are required for regulation of Chk2 by Wip1.

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.138

7 January 2021

The Wip1 phosphatase (PPM1D) antagonizes activation of the Chk2 tumour suppressor kinase

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.138

7 January 2021

Wip1 Phosphatase Modulates ATM-Dependent Signaling Pathways

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.138

7 January 2021

Regulation of ATM/p53-dependent suppression of myc-induced lymphomas by Wip1 phosphatase

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.138

7 January 2021

The Wip1 phosphatase PPM1D dephosphorylates SQ/TQ motifs in checkpoint substrates phosphorylated by PI3K-like kinases

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.138

7 January 2021

The Wip1 Phosphatase acts as a gatekeeper in the p53-Mdm2 autoregulatory loop

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.138

7 January 2021

Inactivation of the Wip1 phosphatase inhibits mammary tumorigenesis through p38 MAPK-mediated activation of the p16(Ink4a)-p19(Arf) pathway

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.138

7 January 2021

Augmented cancer resistance and DNA damage response phenotypes in PPM1D null mice.

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.138

7 January 2021

The role of the MKK6/p38 MAPK pathway in Wip1-dependent regulation of ErbB2-driven mammary gland tumorigenesis.

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.138

7 January 2021

Wild-type p53 protein undergoes cytoplasmic sequestration in undifferentiated neuroblastomas but not in differentiated tumors

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.138

7 January 2021

Evidence that wild-type p53 in neuroblastoma cells is in a conformation refractory to integration into the transcriptional complex

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.138

7 January 2021

Parc: a cytoplasmic anchor for p53.

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.138

7 January 2021

Effects on normal fibroblasts and neuroblastoma cells of the activation of the p53 response by the nuclear export inhibitor leptomycin B.

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.138

7 January 2021

Hyperubiquitylation of wild-type p53 contributes to cytoplasmic sequestration in neuroblastoma

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.138

7 January 2021

Nitric oxide promotes p53 nuclear retention and sensitizes neuroblastoma cells to apoptosis by ionizing radiation

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.138

7 January 2021

A leucine-rich nuclear export signal in the p53 tetramerization domain: regulation of subcellular localization and p53 activity by NES masking

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.138

7 January 2021

Nuclear exclusion of p53 in a subset of tumors requires MDM2 function

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.138

7 January 2021

Human polyomavirus BK (BKV) and neuroblastoma: mechanisms of oncogenic action and possible strategy for novel treatment

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.138

7 January 2021

Negative cross-talk between p53 and the glucocorticoid receptor and its role in neuroblastoma cells

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.138

7 January 2021

Cytoplasmic tethering is involved in synergistic inhibition of p53 by Mdmx and Mdm2.

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.138

7 January 2021

Cytoplasmically "sequestered" wild type p53 protein is resistant to Mdm2-mediated degradation

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.138

7 January 2021

Myc signaling via the ARF tumor suppressor regulates p53-dependent apoptosis and immortalization

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.138

7 January 2021

Repression of the Arf tumor suppressor by E2F3 is required for normal cell cycle kinetics

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.138

7 January 2021

Distinct E2F-mediated transcriptional program regulates p14ARF gene expression

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.138

7 January 2021

MDM2 inhibition sensitizes neuroblastoma to chemotherapy-induced apoptotic cell death

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.138

7 January 2021

Antitumor activity of the selective MDM2 antagonist nutlin-3 against chemoresistant neuroblastoma with wild-type p53.

1 reference

https://api.crossref.org/works/10.1038%2FCDD.2009.138

7 January 2021