(Q37836908)

24 August 2017

1 reference

title

The role of cytokines in the regulation of drug disposition: extended functional pleiotropism? (English)

1 reference

24 August 2017

Neill James Liptrott

1

0 references

Andrew Owen

object named as

Andrew Owen

series ordinal

2

0 references

language of work or name

English

0 references

publication date

8 February 2011

1 reference

Expert Opinion on Drug Metabolism & Toxicology

24 August 2017

published in

1 reference

24 August 2017

volume

7

1 reference

24 August 2017

issue

3

1 reference

24 August 2017

page(s)

341-352

1 reference

Drug metabolism and variability among patients in drug response

24 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.553600

Regulation of drug-metabolizing enzymes and transporters in inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.553600

Evaluation of drug-transporter interactions using in vitro and in vivo models

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.553600

Impact of drug transporters on cellular resistance towards saquinavir and darunavir

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.553600

Molecular mechanisms of drug resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.553600

Intracellular Pharmacokinetics of Antiretroviral Drugs in HIV-Infected Patients, and their Correlation with Drug Action

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.553600

Induction of metabolism and transport in human intestine: validation of precision-cut slices as a tool to study induction of drug metabolism in human intestine in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.553600

Differences in the pharmacokinetics of protease inhibitors between healthy volunteers and HIV-infected persons

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.553600

Bridging the pharmacokinetics and pharmacodynamics of UK-279,276 across healthy volunteers and stroke patients using a mechanistically based model for target-mediated disposition.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.553600

Population pharmacokinetics of tipifarnib in healthy subjects and adult cancer patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.553600

Alterations in gastric acidity in patients infected with human immunodeficiency virus

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.553600

Variations of CYP3A activity induced by antiretroviral treatment in HIV-1 infected patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.553600

Variability in activity of hepatic CYP3A4 in patients infected with HIV.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.553600

Naproxen pharmacokinetics in patients with rheumatoid arthritis during active polyarticular inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.553600

Cytokines in the pathogenesis of rheumatoid arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.553600

Role of cytokines and cytokine therapy in wound healing and fibrotic diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.553600

The changes in the T helper 1 (Th1) and T helper 2 (Th2) cytokine balance during HIV-1 infection are indicative of an allergic response to viral proteins that may be reversed by Th2 cytokine inhibitors and immune response modifiers--a review and hyp

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.553600

Differential tumor surveillance by natural killer (NK) and NKT cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.553600

IFNgamma and lymphocytes prevent primary tumour development and shape tumour immunogenicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.553600

Interleukin 6 is essential for in vivo development of B lineage neoplasms

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.553600

Regulation of drug metabolism and disposition during inflammation and infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.553600

Cytochrome P450 mediated-drug metabolism is reduced in children with sepsis-induced multiple organ failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.553600

Inhibition of P-glycoprotein and multidrug resistance-associated proteins modulates the intracellular concentration of lopinavir in cultured CD4 T cells and primary human lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.553600

The impact of host pharmacogenetics on antiretroviral drug disposition

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.553600

A simplified approach to determining P-glycoprotein expression in peripheral blood mononuclear cell subsets

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.553600

Differential activity of P-glycoprotein in normal blood lymphocyte subsets

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.553600

Altered expression and function of P-glycoprotein (170 kDa), encoded by the MDR 1 gene, in T cell subsets from aging humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.553600

Human T cell cytokine responses are dependent on multidrug resistance protein-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.553600

Quantitative determination of the human MRP1 and MRP2 mRNA expression in FACS-sorted peripheral blood CD4+, CD8+, CD19+, and CD56+ cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.553600

Functional correlation of P-glycoprotein expression and genotype with expression of the human immunodeficiency virus type 1 coreceptor CXCR4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.553600

P-glycoprotein (MDR 1 gene product) in cells of the immune system: its possible physiologic role and alteration in aging and human immunodeficiency virus-1 (HIV-1) infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.553600

Expression of adenosine triphosphate-binding cassette (ABC) drug transporters in peripheral blood cells: relevance for physiology and pharmacotherapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.553600

Relevance of the organic cation transporters 1 and 2 for antiretroviral drug therapy in human immunodeficiency virus infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.553600

Intracellular accumulation of efavirenz and nevirapine is independent of P-glycoprotein activity in cultured CD4 T cells and primary human lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.553600

Subcellular localization and activity of multidrug resistance proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.553600

Effects of uremic toxins on hepatic uptake and metabolism of erythromycin

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.553600

Characterization of two splice variants of human organic anion transporting polypeptide 3A1 isolated from human brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.553600

The impact of cytokines on the expression of drug transporters, cytochrome P450 enzymes and chemokine receptors in human PBMC.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.553600

Potential role of ABC transporters as a detoxification system at the blood-CSF barrier.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.553600

An assessment of P-glycoprotein expression and activity in peripheral blood lymphocytes of transplant candidates

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.553600

Antitumorigenic effects of HIV protease inhibitor ritonavir: inhibition of Kaposi sarcoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.553600

Dendritic cell migration to lymph nodes: cytokines, chemokines, and lipid mediators

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.553600

The gut as a barrier to drug absorption: combined role of cytochrome P450 3A and P-glycoprotein

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.553600

Overlapping substrate specificities and tissue distribution of cytochrome P450 3A and P-glycoprotein: implications for drug delivery and activity in cancer chemotherapy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.553600

The effects of ketoconazole on the intestinal metabolism and bioavailability of cyclosporine*

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.553600

Expression of the drug transporters MDR1/ABCB1, MRP1/ABCC1, MRP2/ABCC2, BCRP/ABCG2, and PXR in peripheral blood mononuclear cells and their relationship with the expression in intestine and liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.553600

Regulation of human hepatic drug transporter expression by pro-inflammatory cytokines

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.553600

Decreased expression and activity of P-glycoprotein in rat liver during acute inflammation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.553600

Effect of hr-IL2 treatment on intestinal P-glycoprotein expression and activity in Caco-2 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.553600

Effect of interleukin-2 pretreatment on paclitaxel absorption and tissue disposition after oral and intravenous administration in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.553600

Effects of proinflammatory cytokines on rat organic anion transporters during toxic liver injury and cholestasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.553600

JAK/STAT-dependent gene regulation by cytokines.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.553600

Cytokine activation of p38 mitogen-activated protein kinase and apoptosis is opposed by alpha-4 targeting of protein phosphatase 2A for site-specific dephosphorylation of MEK3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.553600

Interleukin-6-induced STAT3 and AP-1 amplify hepatocyte nuclear factor 1-mediated transactivation of hepatic genes, an adaptive response to liver injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.553600

The IFN-gamma-dependent suppressor of cytokine signaling 1 promoter activity is positively regulated by IFN regulatory factor-1 and Sp1 but repressed by growth factor independence-1b and Krüppel-like factor-4, and it is dysregulated in psoriatic ker

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.553600

Curcumin inhibits experimental allergic encephalomyelitis by blocking IL-12 signaling through Janus kinase-STAT pathway in T lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.553600

Interleukin-6 induces cellular insulin resistance in hepatocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.553600

NF-kappaB transcription factor induces drug resistance through MDR1 expression in cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.553600

Activation of innate immunity system during aging: NF-kB signaling is the molecular culprit of inflamm-aging

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.553600

Targeted cleavage of signaling proteins by caspase 3 inhibits T cell receptor signaling in anergic T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.553600

Rituximab-mediated cell signaling and chemo/immuno-sensitization of drug-resistant B-NHL is independent of its Fc functions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.553600

SB203580, a specific inhibitor of p38-MAPK pathway, is a new reversal agent of P-glycoprotein-mediated multidrug resistance.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.553600

Doxorubicin induces expression of multidrug resistance-associated protein 1 in human small cell lung cancer cell lines by the c-jun N-terminal kinase pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.553600

Promoter characterization and genomic organization of the human breast cancer resistance protein (ATP-binding cassette transporter G2) gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.553600

The role of the p38 mitogen-activated protein kinase, extracellular signal-regulated kinase, and phosphoinositide-3-OH kinase signal transduction pathways in CD40 ligand-induced dendritic cell activation and expansion of virus-specific CD8+ T cell m

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.553600

The novel Akt inhibitor, perifosine, induces caspase-dependent apoptosis and downregulates P-glycoprotein expression in multidrug-resistant human T-acute leukemia cells by a JNK-dependent mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.553600

IL-6 signal transduction and its physiological roles: the signal orchestration model

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.553600

Cytokines and the hepatic acute phase response

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.553600

Methylation-controlled J protein promotes c-Jun degradation to prevent ABCB1 transporter expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.553600

Interleukin-6-specific activation of the C/EBPdelta gene in hepatocytes is mediated by Stat3 and Sp1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.553600

Identification of a novel polymorphic enhancer of the human CYP3A4 gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.553600

Nuclear receptors and inflammation control: molecular mechanisms and pathophysiological relevance

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.553600

Nuclear receptors and drug disposition gene regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.553600

The orphan nuclear receptor SXR coordinately regulates drug metabolism and efflux

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.553600

Construction and characterization of a fully active PXR/SRC-1 tethered protein with increased stability

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.553600

Nuclear receptors in human immune cells: expression and correlations.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.553600

Role of orphan nuclear receptors in the regulation of drug-metabolising enzymes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.553600

Identification of macrophage liver X receptors as inhibitors of atherosclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.553600

Macrophage PPAR gamma is required for normal skeletal muscle and hepatic insulin sensitivity and full antidiabetic effects of thiazolidinediones

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.553600

Innate immune system regulation of nuclear hormone receptors in metabolic diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.553600

Mutual repression between steroid and xenobiotic receptor and NF-kappaB signaling pathways links xenobiotic metabolism and inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.553600

Role of NF-kappaB in regulation of PXR-mediated gene expression: a mechanism for the suppression of cytochrome P-450 3A4 by proinflammatory agents.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.553600

Interleukin 1beta inhibits CAR-induced expression of hepatic genes involved in drug and bilirubin clearance

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.553600

The involvement of the pregnane X receptor in hepatic gene regulation during inflammation in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.553600

Nuclear receptors are involved in the enhanced IL-6 production by melatonin in U937 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.553600

Combined effect of 25-hydroxycholesterol and IL-1beta on IL-8 production in human colon carcinoma cell line (Caco-2).

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.553600

Kupffer cell-mediated IL-2 suppression of CYP3A activity in human hepatocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.553600

T helper 17 lineage differentiation is programmed by orphan nuclear receptors ROR alpha and ROR gamma

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.553600

PPARgamma promotes mannose receptor gene expression in murine macrophages and contributes to the induction of this receptor by IL-13.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.553600

Pregnane-X-receptor mediates the anti-inflammatory activities of rifaximin on detoxification pathways in intestinal epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.553600

IFN-gamma down-regulates ABCA1 expression by inhibiting LXRalpha in a JAK/STAT signaling pathway-dependent manner

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.553600

P450 superfamily: update on new sequences, gene mapping, accession numbers and nomenclature.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.553600

Detection of ABCC2, CYP2B6 and CYP3A4 in human peripheral blood mononuclear cells using flow cytometry

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17425255.2011.553600

10.1517/17425255.2011.553600

21 January 2018

Identifiers

DOI

1 reference

24 August 2017

1 reference