(Q37861625)

24 August 2017

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title

The tumor suppressor role of CTCF. (English)

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24 August 2017

2

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Francesco Paolo Fiorentino

24 August 2017

object named as

Francesco Paolo Fiorentino

series ordinal

1

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publication date

1 February 2012

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Journal of Cellular Physiology

24 August 2017

published in

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24 August 2017

volume

227

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24 August 2017

issue

2

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24 August 2017

page(s)

479-492

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Translational and rotational settings of H2A.Z nucleosomes across the Saccharomyces cerevisiae genome.

24 August 2017

cites work

1 reference

MYC in oncogenesis and as a target for cancer therapies

21 January 2018

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Involvement of the cyclin-dependent kinase inhibitor p16 (INK4a) in replicative senescence of normal human fibroblasts

21 January 2018

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Transcription factor access is mediated by accurately positioned nucleosomes on the mouse mammary tumor virus promoter.

21 January 2018

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The insulator protein CTCF represses transcription on binding to the (gt)(22)(ga)(15) microsatellite in intron 2 of the HLA-DRB1(*)0401 gene

21 January 2018

1 reference

Negative transcriptional regulation mediated by thyroid hormone response element 144 requires binding of the multivalent factor CTCF to a novel target DNA sequence

21 January 2018

1 reference

Modular structure of a chicken lysozyme silencer: involvement of an unusual thyroid hormone receptor binding site

21 January 2018

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CTCFBSDB: a CTCF-binding site database for characterization of vertebrate genomic insulators

21 January 2018

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High-resolution profiling of histone methylations in the human genome

21 January 2018

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The protein CTCF is required for the enhancer blocking activity of vertebrate insulators

21 January 2018

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An embryonic stem cell-like gene expression signature in poorly differentiated aggressive human tumors

21 January 2018

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The complex language of chromatin regulation during transcription

21 January 2018

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High-resolution genome-wide in vivo footprinting of diverse transcription factors in human cells

21 January 2018

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The Polycomb group proteins bind throughout the INK4A-ARF locus and are disassociated in senescent cells

21 January 2018

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Negative protein 1, which is required for function of the chicken lysozyme gene silencer in conjunction with hormone receptors, is identical to the multivalent zinc finger repressor CTCF.

21 January 2018

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INK4 proteins, a family of mammalian CDK inhibitors with novel biological functions.

21 January 2018

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CTCF interacts with and recruits the largest subunit of RNA polymerase II to CTCF target sites genome-wide

21 January 2018

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Dissecting the unique role of the retinoblastoma tumor suppressor during cellular senescence

21 January 2018

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TSA-induced DNMT1 down-regulation represses hTERT expression via recruiting CTCF into demethylated core promoter region of hTERT in HCT116.

21 January 2018

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Intrinsic variability of gene expression encoded in nucleosome positioning sequences.

21 January 2018

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p107 and p130: versatile proteins with interesting pockets

21 January 2018

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Histone deacetylation is involved in the transcriptional repression of hTERT in normal human cells

21 January 2018

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Aberrant CpG-island methylation has non-random and tumour-type-specific patterns.

21 January 2018

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E2F-1 represses transcription of the human telomerase reverse transcriptase gene

21 January 2018

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Global analysis of the insulator binding protein CTCF in chromatin barrier regions reveals demarcation of active and repressive domains

21 January 2018

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Telomerase regulation at the crossroads of cell fate

21 January 2018

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BORIS, a paralogue of the transcription factor, CTCF, is aberrantly expressed in breast tumours

21 January 2018

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Insights into distinct regulatory modes of nucleosome positioning

21 January 2018

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The c-Myc target gene network

21 January 2018

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Ablation of the retinoblastoma gene family deregulates G(1) control causing immortalization and increased cell turnover under growth-restricting conditions

21 January 2018

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Myc-ARF (alternate reading frame) interaction inhibits the functions of Myc.

21 January 2018

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CTCF promotes muscle differentiation by modulating the activity of myogenic regulatory factors

21 January 2018

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Cytosine methylation transforms an E2F site in the retinoblastoma gene promoter into a binding site for the general repressor methylcytosine-binding protein 2 (MeCP2).

21 January 2018

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Heightened expression of CTCF in breast cancer cells is associated with resistance to apoptosis.

21 January 2018

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Identification of a Ctcf cofactor, Yy1, for the X chromosome binary switch.

21 January 2018

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Cytosine methylation profiling of cancer cell lines.

21 January 2018

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CTCF binding site classes exhibit distinct evolutionary, genomic, epigenomic and transcriptomic features.

21 January 2018

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Aberrant DNA methylation as a cancer-inducing mechanism

21 January 2018

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Cancer epigenomics: DNA methylomes and histone-modification maps

21 January 2018

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Mutational analysis of the poly(ADP-ribosyl)ation sites of the transcription factor CTCF provides an insight into the mechanism of its regulation by poly(ADP-ribosyl)ation

21 January 2018

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The history of cancer epigenetics

21 January 2018

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Epigenetic reprogramming by adenovirus e1a.

21 January 2018

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An exceptionally conserved transcriptional repressor, CTCF, employs different combinations of zinc fingers to bind diverged promoter sequences of avian and mammalian c-myc oncogenes

21 January 2018

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Senescence and p130/Rbl2: a new beginning to the end.

21 January 2018

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CTCF and BORIS regulate Rb2/p130 gene transcription: a novel mechanism and a new paradigm for understanding the biology of lung cancer

21 January 2018

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Enforced expression of the c-myc oncogene inhibits cell differentiation by precluding entry into a distinct predifferentiation state in G0/G1.

21 January 2018

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The insulator binding protein CTCF positions 20 nucleosomes around its binding sites across the human genome

21 January 2018

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c-Myc promotes differentiation of human epidermal stem cells

21 January 2018

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CpG islands in vertebrate genomes

21 January 2018

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Insulators: exploiting transcriptional and epigenetic mechanisms

21 January 2018

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Regulation of the INK4b-ARF-INK4a tumour suppressor locus: all for one or one for all.

21 January 2018

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The c-myc insulator element and matrix attachment regions define the c-myc chromosomal domain

21 January 2018

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Targeted deletion of multiple CTCF-binding elements in the human C-MYC gene reveals a requirement for CTCF in C-MYC expression

21 January 2018

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Domain organization of human chromosomes revealed by mapping of nuclear lamina interactions

21 January 2018

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Abnormalities in structure and expression of the human retinoblastoma gene in SCLC.

21 January 2018

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Induction of apoptosis in HeLa cells by trans-activation-deficient p53.

21 January 2018

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CTCF regulates cell cycle progression of alphabeta T cells in the thymus

21 January 2018

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Histone modifications at human enhancers reflect global cell-type-specific gene expression

21 January 2018

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Regulation of cellular senescence by Rb2/p130.

21 January 2018

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Rb2/p130 is the dominating pocket protein in the p53-p21 DNA damage response pathway leading to senescence

21 January 2018

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The proto-oncogene c-myc in hematopoietic development and leukemogenesis

21 January 2018

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CTCF-dependent enhancer-blocking by alternative chromatin loop formation

21 January 2018

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The histone deacetylase inhibitor trichostatin A derepresses the telomerase reverse transcriptase (hTERT) gene in human cells

21 January 2018

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pRb-expressing adenovirus Ad5-Rb attenuates the p53-induced apoptosis in cervical cancer cell lines.

21 January 2018

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Down-regulation of Myc is essential for terminal erythroid maturation

21 January 2018

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Genome-wide identification of in vivo protein-DNA binding sites from ChIP-Seq data

21 January 2018

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Multiple nucleosome positioning sites regulate the CTCF-mediated insulator function of the H19 imprinting control region

21 January 2018

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Cooperation between p53 and p130(Rb2) in induction of cellular senescence

21 January 2018

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RB, the conductor that orchestrates life, death and differentiation

21 January 2018

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Analysis of the vertebrate insulator protein CTCF-binding sites in the human genome

21 January 2018

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The regulation of INK4/ARF in cancer and aging

21 January 2018

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Sumoylation modulates a domain in CTCF that activates transcription and decondenses chromatin

21 January 2018

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CTCF, a conserved nuclear factor required for optimal transcriptional activity of the chicken c-myc gene, is an 11-Zn-finger protein differentially expressed in multiple forms

21 January 2018

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Functional phosphorylation sites in the C-terminal region of the multivalent multifunctional transcriptional factor CTCF

21 January 2018

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The novel BORIS + CTCF gene family is uniquely involved in the epigenetics of normal biology and cancer

21 January 2018

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pRB family proteins are required for H3K27 trimethylation and Polycomb repression complexes binding to and silencing p16INK4alpha tumor suppressor gene.

21 January 2018

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Ink4a/Arf expression is a biomarker of aging

21 January 2018

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DNA methylation prevents CTCF-mediated silencing of the oncogene BCL6 in B cell lymphomas.

21 January 2018

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The LPS-induced transcriptional upregulation of the chicken lysozyme locus involves CTCF eviction and noncoding RNA transcription.

21 January 2018

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The Ink4/Arf locus is a barrier for iPS cell reprogramming

21 January 2018

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Histone deacetylase inhibitor, Trichostatin A, activates p21WAF1/CIP1 expression through downregulation of c-myc and release of the repression of c-myc from the promoter in human cervical cancer cells

21 January 2018

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Evolutionarily conserved multisubunit RBL2/p130 and E2F4 protein complex represses human cell cycle-dependent genes in quiescence

21 January 2018

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BORIS, a novel male germ-line-specific protein associated with epigenetic reprogramming events, shares the same 11-zinc-finger domain with CTCF, the insulator protein involved in reading imprinting marks in the soma

21 January 2018

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Intrinsic tumour suppression

21 January 2018

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Transcriptional repression by the insulator protein CTCF involves histone deacetylases

21 January 2018

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Thyroid hormone-regulated enhancer blocking: cooperation of CTCF and thyroid hormone receptor

21 January 2018

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The CTCF insulator protein is posttranslationally modified by SUMO.

21 January 2018

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The insulator factor CTCF controls MHC class II gene expression and is required for the formation of long-distance chromatin interactions

21 January 2018

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Deregulation of H3K27 methylation in cancer

21 January 2018

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Telomerase maintains telomere structure in normal human cells.

21 January 2018

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Sulforaphane causes epigenetic repression of hTERT expression in human breast cancer cell lines

21 January 2018

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CTCF is conserved from Drosophila to humans and confers enhancer blocking of the Fab-8 insulator

21 January 2018

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Connections between epigenetic gene silencing and human disease

21 January 2018

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The binding sites for the chromatin insulator protein CTCF map to DNA methylation-free domains genome-wide

21 January 2018

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Cellular senescence: molecular mechanisms, in vivo significance, and redox considerations

21 January 2018

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The retinoblastoma gene family: cousins with overlapping interests

21 January 2018

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Rb-mediated heterochromatin formation and silencing of E2F target genes during cellular senescence

21 January 2018

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A novel role for high-mobility group a proteins in cellular senescence and heterochromatin formation

21 January 2018

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Loss of Parp-1 affects gene expression profile in a genome-wide manner in ES cells and liver cells

21 January 2018

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CTCF is a uniquely versatile transcription regulator linked to epigenetics and disease

21 January 2018

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Does CTCF mediate between nuclear organization and gene expression?

21 January 2018

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Opposing effects of Ets and Id proteins on p16INK4a expression during cellular senescence

21 January 2018

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The ARF tumor suppressor: structure, functions and status in cancer

21 January 2018

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Cohesins functionally associate with CTCF on mammalian chromosome arms

21 January 2018

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An element in the region responsible for premature termination of transcription mediates repression of c-myc gene expression by thyroid hormone in neuroblastoma cells

21 January 2018

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CTCF: master weaver of the genome

21 January 2018

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CTCF functions as a critical regulator of cell-cycle arrest and death after ligation of the B cell receptor on immature B cells

21 January 2018

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E2F mediates cell cycle-dependent transcriptional repression in vivo by recruitment of an HDAC1/mSin3B corepressor complex

21 January 2018

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CTCF binds the proximal exonic region of hTERT and inhibits its transcription

21 January 2018

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Dual role of DNA methylation inside and outside of CTCF-binding regions in the transcriptional regulation of the telomerase hTERT gene

21 January 2018

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BORIS/CTCFL-mediated transcriptional regulation of the hTERT telomerase gene in testicular and ovarian tumor cells

21 January 2018

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Global expression analysis of cancer/testis genes in uterine cancers reveals a high incidence of BORIS expression

21 January 2018

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CTCF is a DNA methylation-sensitive positive regulator of the INK/ARF locus

21 January 2018

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CTCF physically links cohesin to chromatin

21 January 2018

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Targeted disruption of the three Rb-related genes leads to loss of G(1) control and immortalization

21 January 2018

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Oncogenic germ-line mutations in Sp1 and ATF sites in the human retinoblastoma gene

21 January 2018

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INK4a/ARF: a multifunctional tumor suppressor locus

21 January 2018

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The RB and p53 pathways in cancer

21 January 2018

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Roles of the EZH2 histone methyltransferase in cancer epigenetics

21 January 2018

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Functional analysis of CTCF during mammalian limb development

21 January 2018

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Epigenetic regulation of the human p53 gene promoter by the CTCF transcription factor in transformed cell lines.

21 January 2018

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Epigenetic signatures of stem-cell identity.

21 January 2018

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CTCF mediates long-range chromatin looping and local histone modification in the beta-globin locus

21 January 2018

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Cohesins localize with CTCF at the KSHV latency control region and at cellular c-myc and H19/Igf2 insulators

21 January 2018

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Telomerase activation by histone deacetylase inhibitor in normal cells

21 January 2018

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Function of AP-1 in transcription of the telomerase reverse transcriptase gene (TERT) in human and mouse cells

21 January 2018

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Two strategies for gene regulation by promoter nucleosomes

21 January 2018

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CTCF regulates growth and erythroid differentiation of human myeloid leukemia cells.

21 January 2018

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MYC as a regulator of ribosome biogenesis and protein synthesis

21 January 2018

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21 January 2018

Surfing the p53 network

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The zinc finger protein CTCF binds to the APBbeta domain of the amyloid beta-protein precursor promoter. Evidence for a role in transcriptional activation

21 January 2018

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P53 and prognosis: new insights and further complexity

21 January 2018

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Evidence for a relief of repression mechanism for activation of the human telomerase reverse transcriptase promoter

21 January 2018

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The retinoblastoma protein and cell cycle control

21 January 2018

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The c-myc promoter: still MysterY and challenge

21 January 2018

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The role of CTCF in regulating nuclear organization

21 January 2018

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Epigenetic silencing of the p16(INK4a) tumor suppressor is associated with loss of CTCF binding and a chromatin boundary

21 January 2018

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Stemness, cancer and cancer stem cells

21 January 2018

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Role of hTERT in apoptosis of cervical cancer induced by histone deacetylase inhibitor

21 January 2018

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Systematic discovery of regulatory motifs in conserved regions of the human genome, including thousands of CTCF insulator sites

21 January 2018

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Ets2 maintains hTERT gene expression and breast cancer cell proliferation by interacting with c-Myc.

21 January 2018

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CpG island methylation affects accessibility of the proximal BRCA1 promoter to transcription factors.

21 January 2018

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Reduced transcription of the RB2/p130 gene in human lung cancer

21 January 2018

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N-CoR mediates DNA methylation-dependent repression through a methyl CpG binding protein Kaiso

21 January 2018

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Poly(ADP-ribosyl)ation regulates CTCF-dependent chromatin insulation.

21 January 2018

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Global mapping of c-Myc binding sites and target gene networks in human B cells

21 January 2018

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ARF promotes MDM2 degradation and stabilizes p53: ARF-INK4a locus deletion impairs both the Rb and p53 tumor suppression pathways

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/JCP.22780

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24 August 2017

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