Home
Random
Nearby
Log in
Settings
Donate
About Wikidata
Disclaimers
Search
(Q38459968)
Watch
English
Crossroads of PI3K and Rac pathways.
scientific article published on April 2015
In more languages
edit
Statements
instance of
scholarly article
1 reference
stated in
Europe PubMed Central
PMC publication ID
4601376
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25942647%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 March 2020
review article
1 reference
stated in
Europe PubMed Central
title
Crossroads of PI3K and Rac pathways
(English)
1 reference
stated in
Europe PubMed Central
PMC publication ID
4601376
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25942647%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 March 2020
author
Carlo Cosimo Campa
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMC publication ID
4601376
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25942647%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 March 2020
Elisa Ciraolo
series ordinal
2
1 reference
stated in
Europe PubMed Central
PMC publication ID
4601376
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25942647%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 March 2020
Alessandra Ghigo
series ordinal
3
1 reference
stated in
Europe PubMed Central
PMC publication ID
4601376
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25942647%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 March 2020
Emilio Hirsch
series ordinal
5
object named as
Emilio Hirsch
1 reference
stated in
Europe PubMed Central
PMC publication ID
4601376
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25942647%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 March 2020
Giulia Germena
series ordinal
4
object named as
Giulia Germena
1 reference
stated in
Europe PubMed Central
PMC publication ID
4601376
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25942647%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 March 2020
publication date
5 May 2015
1 reference
stated in
Europe PubMed Central
PMC publication ID
4601376
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25942647%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 March 2020
published in
Small GTPases (journal)
1 reference
stated in
Europe PubMed Central
PMC publication ID
4601376
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25942647%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 March 2020
volume
6
1 reference
stated in
Europe PubMed Central
PMC publication ID
4601376
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25942647%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 March 2020
issue
2
1 reference
stated in
Europe PubMed Central
PMC publication ID
4601376
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25942647%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 March 2020
page(s)
71-80
1 reference
stated in
Europe PubMed Central
PMC publication ID
4601376
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25942647%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 March 2020
cites work
Molecular determinants of PI3Kγ-mediated activation downstream of G-protein-coupled receptors (GPCRs)
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4601376
retrieved
6 September 2017
RAS and RHO families of GTPases directly regulate distinct phosphoinositide 3-kinase isoforms
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4601376
retrieved
6 September 2017
Optical control demonstrates switch-like PIP3 dynamics underlying the initiation of immune cell migration.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4601376
retrieved
6 September 2017
p190RhoGAP has cellular RacGAP activity regulated by a polybasic region
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4601376
retrieved
6 September 2017
Regulation of small GTPases by GEFs, GAPs, and GDIs
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4601376
retrieved
6 September 2017
G protein-coupled receptor-mediated activation of p110β by Gβγ is required for cellular transformation and invasiveness
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4601376
retrieved
6 September 2017
Essential role of class II phosphatidylinositol-3-kinase-C2α in sphingosine 1-phosphate receptor-1-mediated signaling and migration in endothelial cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4601376
retrieved
6 September 2017
Rho family GTPases
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4601376
retrieved
6 September 2017
Phosphoinositide 3-kinase C2β regulates RhoA and the actin cytoskeleton through an interaction with Dbl
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4601376
retrieved
6 September 2017
Regulation of the DH-PH tandem of guanine nucleotide exchange factor for Rho GTPases by phosphoinositides.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4601376
retrieved
6 September 2017
Cooperative activation of PI3K by Ras and Rho family small GTPases
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4601376
retrieved
6 September 2017
A stretch of polybasic residues mediates Cdc42 GTPase-activating protein (CdGAP) binding to phosphatidylinositol 3,4,5-trisphosphate and regulates its GAP activity.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4601376
retrieved
6 September 2017
Phosphoinositide lipid phosphatase SHIP1 and PTEN coordinate to regulate cell migration and adhesion.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4601376
retrieved
6 September 2017
A Gβγ effector, ElmoE, transduces GPCR signaling to the actin network during chemotaxis.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4601376
retrieved
6 September 2017
Structural basis for activation and inhibition of class I phosphoinositide 3-kinases
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4601376
retrieved
6 September 2017
A pharmacological cocktail for arresting actin dynamics in living cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4601376
retrieved
6 September 2017
The 'invisible hand': regulation of RHO GTPases by RHOGDIs
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4601376
retrieved
6 September 2017
Structure of the iSH2 domain of human phosphatidylinositol 3-kinase p85β subunit reveals conformational plasticity in the interhelical turn region
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4601376
retrieved
6 September 2017
Phosphorylation of threonine 154 in p40phox is an important physiological signal for activation of the neutrophil NADPH oxidase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4601376
retrieved
6 September 2017
PtdIns3P and Rac direct the assembly of the NADPH oxidase on a novel, pre-phagosomal compartment during FcR-mediated phagocytosis in primary mouse neutrophils
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4601376
retrieved
6 September 2017
Regulatory subunits of class IA PI3K.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4601376
retrieved
6 September 2017
The regulation of class IA PI 3-kinases by inter-subunit interactions
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4601376
retrieved
6 September 2017
Structural Basis of Membrane Targeting by the Dock180 Family of Rho Family Guanine Exchange Factors (Rho-GEFs)
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4601376
retrieved
6 September 2017
Differential regulation of protrusion and polarity by PI3K during neutrophil motility in live zebrafish
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4601376
retrieved
6 September 2017
Form and flexibility in phosphoinositide 3-kinases
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4601376
retrieved
6 September 2017
Random versus directionally persistent cell migration
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4601376
retrieved
6 September 2017
Mechanical integration of actin and adhesion dynamics in cell migration
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4601376
retrieved
6 September 2017
Phosphoinositide 3-kinases in cell migration
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4601376
retrieved
6 September 2017
Crosstalk between small GTPases and polarity proteins in cell polarization.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4601376
retrieved
6 September 2017
Phosphoinositide 3-kinase p110beta activity: key role in metabolism and mammary gland cancer but not development
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4601376
retrieved
6 September 2017
Structural comparisons of class I phosphoinositide 3-kinases
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4601376
retrieved
6 September 2017
Essential roles of PI(3)K-p110beta in cell growth, metabolism and tumorigenesis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4601376
retrieved
6 September 2017
Moving towards a better understanding of chemotaxis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4601376
retrieved
6 September 2017
The regulation and function of Class III PI3Ks: novel roles for Vps34.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4601376
retrieved
6 September 2017
Negative feedback regulation of Rac in leukocytes from mice expressing a constitutively active phosphatidylinositol 3-kinase gamma
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4601376
retrieved
6 September 2017
Membrane translocation of P-Rex1 is mediated by G protein betagamma subunits and phosphoinositide 3-kinase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4601376
retrieved
6 September 2017
Binding of ras to phosphoinositide 3-kinase p110alpha is required for ras-driven tumorigenesis in mice
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4601376
retrieved
6 September 2017
GEFs and GAPs: critical elements in the control of small G proteins
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4601376
retrieved
6 September 2017
Class IA phosphoinositide 3-kinases are obligate p85-p110 heterodimers
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4601376
retrieved
6 September 2017
GTP-binding proteins of the Rho/Rac family: regulation, effectors and functions in vivo
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4601376
retrieved
6 September 2017
Non-canonical interaction of phosphoinositides with pleckstrin homology domains of Tiam1 and ArhGAP9
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4601376
retrieved
6 September 2017
Current knowledge of the large RhoGAP family of proteins
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4601376
retrieved
6 September 2017
The p110alpha isoform of PI3K is essential for proper growth factor signaling and oncogenic transformation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4601376
retrieved
6 September 2017
PtdIns3P binding to the PX domain of p40phox is a physiological signal in NADPH oxidase activation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4601376
retrieved
6 September 2017
To stabilize neutrophil polarity, PIP3 and Cdc42 augment RhoA activity at the back as well as signals at the front
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4601376
retrieved
6 September 2017
Phosphoinositide 3-Kinase C2beta regulates cytoskeletal organization and cell migration via Rac-dependent mechanisms
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4601376
retrieved
6 September 2017
Neutrophil polarization: spatiotemporal dynamics of RhoA activity support a self-organizing mechanism
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4601376
retrieved
6 September 2017
P-Rex1 is a primary Rac2 guanine nucleotide exchange factor in mouse neutrophils
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4601376
retrieved
6 September 2017
Generation and characterization of Rac3 knockout mice.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4601376
retrieved
6 September 2017
GDIs: central regulatory molecules in Rho GTPase activation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4601376
retrieved
6 September 2017
Vav activation and function as a rac guanine nucleotide exchange factor in macrophage colony-stimulating factor-induced macrophage chemotaxis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4601376
retrieved
6 September 2017
Phosphoinositide 3-kinase catalytic subunit deletion and regulatory subunit deletion have opposite effects on insulin sensitivity in mice
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4601376
retrieved
6 September 2017
GEF means go: turning on RHO GTPases with guanine nucleotide-exchange factors
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4601376
retrieved
6 September 2017
Regulation of P-Rex1 by phosphatidylinositol (3,4,5)-trisphosphate and Gbetagamma subunits
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4601376
retrieved
6 September 2017
The Sec14 homology domain regulates the cellular distribution and transforming activity of the Rho-specific guanine nucleotide exchange factor Dbs.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4601376
retrieved
6 September 2017
NOX enzymes and the biology of reactive oxygen
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4601376
retrieved
6 September 2017
Rho-family GTPases: it's not only Rac and Rho (and I like it).
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4601376
retrieved
6 September 2017
Structural elements, mechanism, and evolutionary convergence of Rho protein-guanine nucleotide exchange factor complexes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4601376
retrieved
6 September 2017
Immunological function in mice lacking the Rac-related GTPase RhoG
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4601376
retrieved
6 September 2017
Vav1/2/3-null Mice Define an Essential Role for Vav Family Proteins in Lymphocyte Development and Activation but a Differential Requirement in MAPK Signaling in T and B Cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4601376
retrieved
6 September 2017
PB1 domain-mediated heterodimerization in NADPH oxidase and signaling complexes of atypical protein kinase C with Par6 and p62
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4601376
retrieved
6 September 2017
Multifunctional roles for the PH domain of Dbs in regulating Rho GTPase activation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4601376
retrieved
6 September 2017
Essential role of phosphoinositide 3-kinase delta in neutrophil directional movement
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4601376
retrieved
6 September 2017
Rac and Cdc42 play distinct roles in regulating PI(3,4,5)P3 and polarity during neutrophil chemotaxis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4601376
retrieved
6 September 2017
Loss of phosphatidylinositol 3-phosphate binding by the C-terminal Tiam-1 pleckstrin homology domain prevents in vivo Rac1 activation without affecting membrane targeting
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4601376
retrieved
6 September 2017
Phosphoinositide 3-kinase activates Rac by entering in a complex with Eps8, Abi1, and Sos-1.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4601376
retrieved
6 September 2017
Roles of G beta gamma in membrane recruitment and activation of p110 gamma/p101 phosphoinositide 3-kinase gamma
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4601376
retrieved
6 September 2017
Rho GTPase-activating proteins in cell regulation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4601376
retrieved
6 September 2017
Rho GTPases in cell biology
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4601376
retrieved
6 September 2017
Mechanism of regulation of WAVE1-induced actin nucleation by Rac1 and Nck
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4601376
retrieved
6 September 2017
Guanine nucleotide exchange factors for Rho GTPases: turning on the switch
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4601376
retrieved
6 September 2017
P-Rex1, a PtdIns(3,4,5)P3- and Gbetagamma-regulated guanine-nucleotide exchange factor for Rac
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4601376
retrieved
6 September 2017
Defective dendrite elongation but normal fertility in mice lacking the Rho-like GTPase activator Dbl.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4601376
retrieved
6 September 2017
Neutrophils lacking phosphoinositide 3-kinase gamma show loss of directionality during N-formyl-Met-Leu-Phe-induced chemotaxis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4601376
retrieved
6 September 2017
A crystallographic view of interactions between Dbs and Cdc42: PH domain-assisted guanine nucleotide exchange
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4601376
retrieved
6 September 2017
The evolutionary history of effectors downstream of Cdc42 and Rac.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4601376
retrieved
6 September 2017
Architecture of the p40-p47-p67phox complex in the resting state of the NADPH oxidase. A central role for p67phox
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4601376
retrieved
6 September 2017
Dbl family guanine nucleotide exchange factors
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4601376
retrieved
6 September 2017
Molecular basis for Rac2 regulation of phagocyte NADPH oxidase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4601376
retrieved
6 September 2017
Dancing to the tune of chemokines
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4601376
retrieved
6 September 2017
Crystal structure and functional analysis of Ras binding to its effector phosphoinositide 3-kinase gamma
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4601376
retrieved
6 September 2017
Crystal structure of Rac1 in complex with the guanine nucleotide exchange region of Tiam1
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4601376
retrieved
6 September 2017
Structural basis for relief of autoinhibition of the Dbl homology domain of proto-oncogene Vav by tyrosine phosphorylation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4601376
retrieved
6 September 2017
Dominant negative mutation of the hematopoietic-specific Rho GTPase, Rac2, is associated with a human phagocyte immunodeficiency
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4601376
retrieved
6 September 2017
Differential expression and regulation of GTPases (RhoA and Rac2) and GDIs (LyGDI and RhoGDI) in neutrophils from patients with severe congenital neutropenia
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4601376
retrieved
6 September 2017
Human neutrophil immunodeficiency syndrome is associated with an inhibitory Rac2 mutation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4601376
retrieved
6 September 2017
Central role for G protein-coupled phosphoinositide 3-kinase gamma in inflammation.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4601376
retrieved
6 September 2017
Roles of PLC-beta2 and -beta3 and PI3Kgamma in chemoattractant-mediated signal transduction
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4601376
retrieved
6 September 2017
Polarization of chemoattractant receptor signaling during neutrophil chemotaxis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4601376
retrieved
6 September 2017
Crystal structure of the Dbl and pleckstrin homology domains from the human Son of sevenless protein
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4601376
retrieved
6 September 2017
CdGAP, a novel proline-rich GTPase-activating protein for Cdc42 and Rac.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4601376
retrieved
6 September 2017
The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4601376
retrieved
6 September 2017
Role of substrates and products of PI 3-kinase in regulating activation of Rac-related guanosine triphosphatases by Vav
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4601376
retrieved
6 September 2017
MEK kinases are regulated by EGF and selectively interact with Rac/Cdc42
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4601376
retrieved
6 September 2017
Phosphotyrosine-dependent activation of Rac-1 GDP/GTP exchange by the vav proto-oncogene product
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4601376
retrieved
6 September 2017
The Ras GTPase-activating-protein-related human protein IQGAP2 harbors a potential actin binding domain and interacts with calmodulin and Rho family GTPases
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4601376
retrieved
6 September 2017
Activation of phosphoinositide 3-kinase by interaction with Ras and by point mutation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4601376
retrieved
6 September 2017
Wortmannin inactivates phosphoinositide 3-kinase by covalent modification of Lys-802, a residue involved in the phosphate transfer reaction
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4601376
retrieved
6 September 2017
Rac GTPase interacts specifically with phosphatidylinositol 3-kinase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4601376
retrieved
6 September 2017
The 145-kDa protein induced to associate with Shc by multiple cytokines is an inositol tetraphosphate and phosphatidylinositol 3,4,5-triphosphate 5-phosphatase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4601376
retrieved
6 September 2017
Characterization of rhoGAP. A GTPase-activating protein for rho-related small GTPases
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4601376
retrieved
6 September 2017
A brain serine/threonine protein kinase activated by Cdc42 and Rac1
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4601376
retrieved
6 September 2017
Interaction of Rac with p67phox and regulation of phagocytic NADPH oxidase activity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4601376
retrieved
6 September 2017
Activation of phosphoinositide 3-kinase activity by Cdc42Hs binding to p85.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4601376
retrieved
6 September 2017
A conserved binding motif defines numerous candidate target proteins for both Cdc42 and Rac GTPases
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4601376
retrieved
6 September 2017
Catalysis of guanine nucleotide exchange on the CDC42Hs protein by the dbl oncogene product
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4601376
retrieved
6 September 2017
Pathway of phosphatidylinositol(3,4,5)-trisphosphate synthesis in activated neutrophils
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4601376
retrieved
6 September 2017
Sequential regulation of DOCK2 dynamics by two phospholipids during neutrophil chemotaxis.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4601376
retrieved
14 September 2017
Endocytic trafficking of Rac is required for the spatial restriction of signaling in cell migration
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4601376
retrieved
14 September 2017
Inositol phospholipids regulate the guanine-nucleotide-exchange factor Tiam1 by facilitating its binding to the plasma membrane and regulating GDP/GTP exchange on Rac1
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4601376
retrieved
14 September 2017
The Dbs PH domain contributes independently to membrane targeting and regulation of guanine nucleotide-exchange activity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4601376
retrieved
27 September 2017
Mechanism of the regulation of type IB phosphoinositide 3OH-kinase byG-protein betagamma subunits
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4601376
retrieved
27 September 2017
A role for the actin cytoskeleton in the hormonal and growth-factor-mediated activation of protein kinase B.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4601376
retrieved
27 September 2017
Regulation of the Rac1-specific exchange factor Tiam1 involves both phosphoinositide 3-kinase-dependent and -independent components
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4601376
retrieved
27 September 2017
Function of PI3Kgamma in thymocyte development, T cell activation, and neutrophil migration
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4601376
retrieved
27 September 2017
Coupling of Ras and Rac guanosine triphosphatases through the Ras exchanger Sos.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4601376
retrieved
27 September 2017
PH domains: diverse sequences with a common fold recruit signaling molecules to the cell surface
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4601376
retrieved
27 September 2017
PDGF stimulates an increase in GTP-Rac via activation of phosphoinositide 3-kinase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4601376
retrieved
27 September 2017
The PH domain of phosphoinositide-dependent kinase-1 exhibits a novel, phospho-regulated monomer-dimer equilibrium with important implications for kinase domain activation: single-molecule and ensemble studies
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4601376
retrieved
23 June 2018
Mice deficient in the Rac activator Tiam1 are resistant to Ras-induced skin tumours.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4601376
retrieved
23 June 2018
SWAP-70 is a guanine-nucleotide-exchange factor that mediates signalling of membrane ruffling
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4601376
retrieved
23 June 2018
Modulation of oncogenic DBL activity by phosphoinositol phosphate binding to pleckstrin homology domain.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4601376
retrieved
23 June 2018
The 70 kDa S6 kinase complexes with and is activated by the Rho family G proteins Cdc42 and Rac1.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4601376
retrieved
23 June 2018
Wortmannin is a potent phosphatidylinositol 3-kinase inhibitor: the role of phosphatidylinositol 3,4,5-trisphosphate in neutrophil responses.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4601376
retrieved
23 June 2018
Platelet-derived growth factor-induced phosphatidylinositol 3-kinase activation mediates actin rearrangements in fibroblasts
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4601376
retrieved
23 June 2018
Activation of phosphoinositide 3-kinase is required for PDGF-stimulated membrane ruffling
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4601376
retrieved
23 June 2018
Isolation of a new human oncogene from a diffuse B-cell lymphoma.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4601376
retrieved
23 June 2018
Phosphorylation of neutrophil 47-kDa cytosolic oxidase factor. Translocation to membrane is associated with distinct phosphorylation events.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4601376
retrieved
23 June 2018
The cell polarity protein mInsc regulates neutrophil chemotaxis via a noncanonical G protein signaling pathway
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4601376
retrieved
31 August 2018
Endothelial PI3K-C2α, a class II PI3K, has an essential role in angiogenesis and vascular barrier function.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4601376
retrieved
31 August 2018
PI3Kβ plays a critical role in neutrophil activation by immune complexes.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4601376
retrieved
31 August 2018
Signal amplification between Gbetagamma release and PI3Kgamma-mediated PI(3,4,5)P3 formation monitored by a fluorescent Gbetagamma biosensor protein and repetitive two component total internal reflection/fluorescence redistribution after photobleach
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4601376
retrieved
31 August 2018
PTEN functions to 'prioritize' chemotactic cues and prevent 'distraction' in migrating neutrophils
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4601376
retrieved
31 August 2018
PI3K accelerates, but is not required for, neutrophil chemotaxis to fMLP.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4601376
retrieved
31 August 2018
Gbetagammas and the Ras binding domain of p110gamma are both important regulators of PI(3)Kgamma signalling in neutrophils
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4601376
retrieved
31 August 2018
Rac1 GTPase regulates cell genomic stability and senescence.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4601376
retrieved
31 August 2018
Divergent signals and cytoskeletal assemblies regulate self-organizing polarity in neutrophils
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4601376
retrieved
31 August 2018
Lipid products of PI(3)Ks maintain persistent cell polarity and directed motility in neutrophils
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4601376
retrieved
31 August 2018
Role of prenylation in the interaction of Rho-family small GTPases with GTPase activating proteins.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4601376
retrieved
31 August 2018
Rac1 is required for the formation of three germ layers during gastrulation.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4601376
retrieved
31 August 2018
Quantitative Analysis of the Effect of Phosphoinositide Interactions on the Function of Dbl Family Proteins
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4601376
retrieved
31 August 2018
Control of cell polarity and motility by the PtdIns(3,4,5)P3 phosphatase SHIP1
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4601376
retrieved
3 December 2018
PI(3)Kγ has an important context-dependent role in neutrophil chemokinesis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4601376
retrieved
3 December 2018
Signal transduction through Vav-2 participates in humoral immune responses and B cell maturation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4601376
retrieved
3 December 2018
Essential role of Rac1 and Rac3 GTPases in neuronal development
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/25942647
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
A membrane-permeant ester of phosphatidylinositol 3,4, 5-trisphosphate (PIP(3)) is an activator of human neutrophil migration
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/25942647
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Role of the Guanosine Triphosphatase Rac2 in T Helper 1 Cell Differentiation
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/25942647
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
A Requirement for the Rho-Family GTP Exchange Factor Vav in Positive and Negative Selection of Thymocytes
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/25942647
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Kinetic analysis by fluorescence of the interaction between Ras and the catalytic domain of the guanine nucleotide exchange factor Cdc25Mm
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/25942647
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
The mitogen-activated protein kinase extracellular signal-regulated kinase 1/2 pathway is involved in formyl-methionyl-leucyl-phenylalanine-induced p47phox phosphorylation in human neutrophils
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/25942647
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Compensation between Vav-1 and Vav-2 in B cell development and antigen receptor signaling
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/25942647
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Roles of non-catalytic subunits in gbetagamma-induced activation of class I phosphoinositide 3-kinase isoforms beta and gamma
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/25942647
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Activation domain in P67phox regulates the steady state reduction of FAD in gp91phox
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/25942647
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
[Expression and significance of EGF mRNA and EGFR mRNA in hepatocellular carcinoma]
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/25942647
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.4161/21541248.2014.989789
1 reference
stated in
Europe PubMed Central
PMC publication ID
4601376
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25942647%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 March 2020
PMC publication ID
4601376
1 reference
stated in
Europe PubMed Central
PMC publication ID
4601376
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25942647%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 March 2020
PubMed publication ID
25942647
1 reference
stated in
Europe PubMed Central
PMC publication ID
4601376
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25942647%20AND%20SRC:MED&resulttype=core&format=json
retrieved
7 March 2020
Sitelinks
Wikipedia
(0 entries)
edit
Wikibooks
(0 entries)
edit
Wikinews
(0 entries)
edit
Wikiquote
(0 entries)
edit
Wikisource
(0 entries)
edit
Wikiversity
(0 entries)
edit
Wikivoyage
(0 entries)
edit
Wiktionary
(0 entries)
edit
Multilingual sites
(0 entries)
edit
