(Q48407966)

11 February 2018

title

Differential display analysis of presenilin 1-deficient mouse brains (English)

1 reference

11 February 2018

Peter Henry St George-Hyslop

author

object named as

Peter St George-Hyslop

4

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author name string

Jennifer Liauw

1

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11 February 2018

Van Nguyen

2

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11 February 2018

Jean Huang

3

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11 February 2018

Richard Rozmahel

5

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11 February 2018

publication date

1 December 2002

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11 February 2018

published in

Molecular Brain Research

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11 February 2018

volume

109

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11 February 2018

issue

1-2

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11 February 2018

page(s)

56-62

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11 February 2018

Cytomechanics of cadherin-mediated cell-cell adhesion

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Does dysregulation of the Notch and wingless/Wnt pathways underlie the pathogenesis of Alzheimer's disease?

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Interaction between Wingless and Notch signaling pathways mediated by dishevelled.

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Familial Alzheimer's disease-linked presenilin 1 variants elevate Abeta1-42/1-40 ratio in vitro and in vivo

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Requirement of the paraxis gene for somite formation and musculoskeletal patterning

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Presenilin 1 mutations activate gamma 42-secretase but reciprocally inhibit epsilon-secretase cleavage of amyloid precursor protein (APP) and S3-cleavage of notch

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Mutant presenilins of Alzheimer's disease increase production of 42-residue amyloid beta-protein in both transfected cells and transgenic mice

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Wnt signaling function in Alzheimer's disease

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A presenilin-1-dependent gamma-secretase-like protease mediates release of Notch intracellular domain

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Deficiency of presenilin-1 inhibits the normal cleavage of amyloid precursor protein

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Increased amyloid-beta42(43) in brains of mice expressing mutant presenilin 1

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Septins: cytoskeletal polymers or signalling GTPases?

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Presenilin-1 forms complexes with the cadherin/catenin cell-cell adhesion system and is recruited to intercellular and synaptic contacts

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Increased vulnerability of hippocampal neurons to excitotoxic necrosis in presenilin-1 mutant knock-in mice

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Maintenance of somite borders in mice requires the Delta homologue DII1.

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Cellular and developmental control of O2 homeostasis by hypoxia-inducible factor 1 alpha

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Hypoxia-inducible factor 1 levels vary exponentially over a physiologically relevant range of O2 tension

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Identification of septins in neurofibrillary tangles in Alzheimer's disease

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Defective vascularization of HIF-1alpha-null embryos is not associated with VEGF deficiency but with mesenchymal cell death

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Are cerebrovascular factors involved in Alzheimer's disease?

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The mouse pudgy mutation disrupts Delta homologue Dll3 and initiation of early somite boundaries

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7 January 2021

Presenilins interact with armadillo proteins including neural-specific plakophilin-related protein and beta-catenin

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7 January 2021

Differential display of eukaryotic messenger RNA by means of the polymerase chain reaction

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delta-catenin, an adhesive junction-associated protein which promotes cell scattering

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7 January 2021

Requirement for presenilin 1 in facilitating lagged 2-mediated endoproteolysis and signaling of notch 1.

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7 January 2021

Presenilin-1 mutation increases neuronal vulnerability to focal ischemia in vivo and to hypoxia and glucose deprivation in cell culture: involvement of perturbed calcium homeostasis

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7 January 2021

Direct association of presenilin-1 with beta-catenin

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Molecular cloning of a novel human cDNA homologous to CDC10 in Saccharomyces cerevisiae

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Roles of Wnt proteins in neural development and maintenance

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7 January 2021

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Cell surface presenilin-1 participates in the gamma-secretase-like proteolysis of Notch

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7 January 2021

Normal brain development in PS1 hypomorphic mice with markedly reduced gamma-secretase cleavage of betaAPP.

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7 January 2021

Secreted amyloid beta-protein similar to that in the senile plaques of Alzheimer's disease is increased in vivo by the presenilin 1 and 2 and APP mutations linked to familial Alzheimer's disease

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7 January 2021

A nuclear factor induced by hypoxia via de novo protein synthesis binds to the human erythropoietin gene enhancer at a site required for transcriptional activation

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7 January 2021

Skeletal and CNS defects in Presenilin-1-deficient mice

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7 January 2021

Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease

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7 January 2021

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7 January 2021

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7 January 2021

gamma-Secretase, Notch, Abeta and Alzheimer's disease: where do the presenilins fit in?

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7 January 2021

Proteolytic release and nuclear translocation of Notch-1 are induced by presenilin-1 and impaired by pathogenic presenilin-1 mutations

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7 January 2021

Presenilin 1 negatively regulates beta-catenin/T cell factor/lymphoid enhancer factor-1 signaling independently of beta-amyloid precursor protein and notch processing

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7 January 2021

Molecular genetics of Alzheimer's disease.

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7 January 2021

Direct interaction of Alzheimer's disease-related presenilin 1 with armadillo protein p0071

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7 January 2021

Evidence for a novel gene associated with low tumor metastatic potential

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7 January 2021

Notch1 is essential for postimplantation development in mice.

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7 January 2021

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7 January 2021

Two transmembrane aspartates in presenilin-1 required for presenilin endoproteolysis and gamma-secretase activity

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7 January 2021

Presenilin 1 is required for Notch1 and DII1 expression in the paraxial mesoderm

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7 January 2021

Impaired physiological responses to chronic hypoxia in mice partially deficient for hypoxia-inducible factor 1alpha

1 reference

https://api.crossref.org/works/10.1016%2FS0169-328X%2802%2900491-6

7 January 2021

The presenilin 1 protein is a component of a high molecular weight intracellular complex that contains beta-catenin

1 reference

https://api.crossref.org/works/10.1016%2FS0169-328X%2802%2900491-6

7 January 2021

Presenilin 1 interaction in the brain with a novel member of the Armadillo family

1 reference

https://api.crossref.org/works/10.1016%2FS0169-328X%2802%2900491-6

7 January 2021

10.1016/S0169-328X(02)00491-6

Identifiers

DOI

1 reference

11 February 2018

1 reference

11 February 2018