(Q28245018)

B cell antigen receptor signaling 101.

21 January 2018

1 reference

ITAM-mediated tonic signalling through pre-BCR and BCR complexes

21 January 2018

1 reference

Mutation of unique region of Bruton's tyrosine kinase in immunodeficient XID mice

21 January 2018

1 reference

Phosphoinositide 3-kinase and its targets in B-cell and T-cell signaling

21 January 2018

1 reference

21 January 2018

1 reference

Regulation of B-cell signal transduction by adaptor proteins

21 January 2018

1 reference

Syk and Bruton's tyrosine kinase are required for B cell antigen receptor-mediated activation of the kinase Akt.

21 January 2018

1 reference

Signal transduction by the B cell antigen receptor and its coreceptors

21 January 2018

1 reference

Tyrosine kinases and their substrates in B lymphocytes

21 January 2018

1 reference

Functional analysis of Csk in signal transduction through the B-cell antigen receptor.

21 January 2018

1 reference

The PTEN, Mdm2, p53 tumor suppressor-oncoprotein network

21 January 2018

1 reference

Differential regulation of B cell development, activation, and death by the src homology 2 domain-containing 5' inositol phosphatase (SHIP)

21 January 2018

1 reference

Immunoreceptor tyrosine-based inhibition motifs

21 January 2018

1 reference

New functions for the sialic acid-binding adhesion molecule CD22, a member of the growing family of Siglecs.

21 January 2018

1 reference

Intrinsic properties of immunoglobulin IgG1 isotype-switched B cell receptors promote microclustering and the initiation of signaling

21 January 2018

1 reference

The membrane skeleton controls diffusion dynamics and signaling through the B cell receptor

21 January 2018

1 reference

Organisation and dynamics of antigen receptors: implications for lymphocyte signalling

21 January 2018

1 reference

In vivo ablation of surface immunoglobulin on mature B cells by inducible gene targeting results in rapid cell death.

21 January 2018

1 reference

PI3 kinase signals BCR-dependent mature B cell survival

21 January 2018

1 reference

Essential function for the GTPase TC21 in homeostatic antigen receptor signaling.

21 January 2018

1 reference

Csk controls antigen receptor-mediated development and selection of T-lineage cells.

21 January 2018

1 reference

Evidence for a preformed transducer complex organized by the B cell antigen receptor

21 January 2018

1 reference

A gene expression-based method to diagnose clinically distinct subgroups of diffuse large B cell lymphoma

21 January 2018

1 reference

Chronic active B-cell-receptor signalling in diffuse large B-cell lymphoma

21 January 2018

1 reference

Chronic lymphocytic leukaemia is driven by antigen-independent cell-autonomous signalling

21 January 2018

1 reference

21 January 2018

1 reference

Mechanisms of B-cell lymphoma pathogenesis

21 January 2018

1 reference

Aberrant immunoglobulin class switch recombination and switch translocations in activated B cell-like diffuse large B cell lymphoma

21 January 2018

1 reference

Recruitment of the cytoplasmic adaptor Grb2 to surface IgG and IgE provides antigen receptor-intrinsic costimulation to class-switched B cells

21 January 2018

1 reference

A distinct signaling pathway used by the IgG-containing B cell antigen receptor

21 January 2018

1 reference

Enhancement and suppression of signaling by the conserved tail of IgG memory-type B cell antigen receptors

21 January 2018

1 reference

Burst-enhancing role of the IgG membrane tail as a molecular determinant of memory.

21 January 2018

1 reference

The use of molecular profiling to predict survival after chemotherapy for diffuse large-B-cell lymphoma

21 January 2018

1 reference

Oncogenic CARD11 mutations in human diffuse large B cell lymphoma

21 January 2018

1 reference

A loss-of-function RNA interference screen for molecular targets in cancer

21 January 2018

1 reference

Over 20% of patients with chronic lymphocytic leukemia carry stereotyped receptors: Pathogenetic implications and clinical correlations.

21 January 2018

1 reference

21 January 2018

1 reference

Is there a role for antigen selection in mantle cell lymphoma? Immunogenetic support from a series of 807 cases

21 January 2018

1 reference

Unmutated and mutated chronic lymphocytic leukemias derive from self-reactive B cell precursors despite expressing different antibody reactivity

21 January 2018

1 reference

Chronic lymphocytic leukemia cells recognize conserved epitopes associated with apoptosis and oxidation

21 January 2018

1 reference

Chronic lymphocytic leukemia antibodies with a common stereotypic rearrangement recognize nonmuscle myosin heavy chain IIA.

21 January 2018

1 reference

A new perspective: molecular motifs on oxidized LDL, apoptotic cells, and bacteria are targets for chronic lymphocytic leukemia antibodies

21 January 2018

1 reference

Stereotypical chronic lymphocytic leukemia B-cell receptors recognize survival promoting antigens on stromal cells

21 January 2018

1 reference

A mutated B cell chronic lymphocytic leukemia subset that recognizes and responds to fungi.

21 January 2018

1 reference

IGHV1-69-encoded antibodies expressed in chronic lymphocytic leukemia react with malondialdehyde-acetaldehyde adduct, an immunodominant oxidation-specific epitope

21 January 2018

1 reference

SF3B1 and other novel cancer genes in chronic lymphocytic leukemia

21 January 2018

1 reference

Whole-genome sequencing identifies recurrent mutations in chronic lymphocytic leukaemia

21 January 2018

1 reference

Multidimensional single-cell analysis of BCR signaling reveals proximal activation defect as a hallmark of chronic lymphocytic leukemia B cells.

21 January 2018

1 reference

miR-150 influences B-cell receptor signaling in chronic lymphocytic leukemia by regulating expression of GAB1 and FOXP1

21 January 2018

1 reference

MicroRNAs and B cell receptor signaling in chronic lymphocytic leukemia

21 January 2018

1 reference

MicroRNA-155 influences B-cell receptor signaling and associates with aggressive disease in chronic lymphocytic leukemia

21 January 2018

1 reference

Syk-dependent mTOR activation in follicular lymphoma cells.

21 January 2018

1 reference

Proteomic analysis of apoptotic pathways reveals prognostic factors in follicular lymphoma

21 January 2018

1 reference

Genomic and expression profiling identifies the B-cell associated tyrosine kinase Syk as a possible therapeutic target in mantle cell lymphoma

21 January 2018

1 reference

Molecular pathogenesis of mantle cell lymphoma

21 January 2018

1 reference

Amplification of B cell antigen receptor signaling by a Syk/ITAM positive feedback loop

21 January 2018

1 reference

Ig beta tyrosine residues contribute to the control of B cell receptor signaling by regulating receptor internalization

21 January 2018

1 reference

Visualization of Syk-antigen receptor interactions using green fluorescent protein: differential roles for Syk and Lyn in the regulation of receptor capping and internalization

21 January 2018

1 reference

Developmental acquisition of the Lyn-CD22-SHP-1 inhibitory pathway promotes B cell tolerance

21 January 2018

1 reference

Molecular underpinning of B-cell anergy

21 January 2018

1 reference

Chronic lymphocytic leukemia B cells contain anomalous Lyn tyrosine kinase, a putative contribution to defective apoptosis

21 January 2018

1 reference

Oncogenically active MYD88 mutations in human lymphoma

21 January 2018

1 reference

Helical assembly in the MyD88–IRAK4–IRAK2 complex in TLR/IL-1R signalling

21 January 2018

1 reference

Constitutively activated STAT3 promotes cell proliferation and survival in the activated B-cell subtype of diffuse large B-cell lymphomas

21 January 2018

1 reference

The "Gab" in signal transduction.

21 January 2018

1 reference

Coupling of Gab1 to c-Met, Grb2, and Shp2 mediates biological responses

21 January 2018

1 reference

The Gab1 protein is a docking site for multiple proteins involved in signaling by the B cell antigen receptor.

21 January 2018

1 reference

The multiple function of Grb2 associated binder (Gab) adaptor/scaffolding protein in immune cell signaling.

21 January 2018

1 reference

The Gab1 docking protein links the b cell antigen receptor to the phosphatidylinositol 3-kinase/Akt signaling pathway and to the SHP2 tyrosine phosphatase.

21 January 2018

1 reference

The microRNA miR-181 is a critical cellular metabolic rheostat essential for NKT cell ontogenesis and lymphocyte development and homeostasis

21 January 2018

1 reference

T cell antigen receptor signal transduction

21 January 2018

1 reference

ZAP-70 is expressed by normal and malignant human B-cell subsets of different maturational stage.

21 January 2018

1 reference

The B-cell receptor and ZAP-70 in chronic lymphocytic leukemia

21 January 2018

1 reference

ZAP-70 directly enhances IgM signaling in chronic lymphocytic leukemia

21 January 2018

1 reference

ZAP-70 compared with immunoglobulin heavy-chain gene mutation status as a predictor of disease progression in chronic lymphocytic leukemia

21 January 2018

1 reference

ZAP-70 enhances IgM signaling independent of its kinase activity in chronic lymphocytic leukemia

21 January 2018

1 reference

ZAP-70 protein promotes tyrosine phosphorylation of T cell receptor signaling motifs (ITAMs) in immature CD4(+)8(+) thymocytes with limiting p56(lck).

21 January 2018

1 reference

Differential intrinsic enzymatic activity of Syk and Zap-70 protein-tyrosine kinases

21 January 2018

1 reference

The non-receptor tyrosine kinase Syk is a target of Cbl-mediated ubiquitylation upon B-cell receptor stimulation.

21 January 2018

1 reference

A direct interaction between the adaptor protein Cbl-b and the kinase zap-70 induces a positive signal in T cells

21 January 2018

1 reference

Cbl-mediated negative regulation of the Syk tyrosine kinase. A critical role for Cbl phosphotyrosine-binding domain binding to Syk phosphotyrosine 323

21 January 2018

1 reference

Targeting Bruton's tyrosine kinase in B cell malignancies

21 January 2018

1 reference

Targeting the microenvironment in chronic lymphocytic leukemia is changing the therapeutic landscape

21 January 2018

1 reference

PI3Kδ inhibitors in cancer: rationale and serendipity merge in the clinic

21 January 2018

1 reference

Targeting BTK with ibrutinib in relapsed chronic lymphocytic leukemia

21 January 2018

1 reference

The Bruton's tyrosine kinase gene is expressed throughout B cell differentiation, from early precursor B cell stages preceding immunoglobulin gene rearrangement up to mature B cell stages

21 January 2018

1 reference

Differential requirements for DOCK2 and phosphoinositide-3-kinase gamma during T and B lymphocyte homing

21 January 2018

1 reference

CXCR3-mediated chemotaxis of human T cells is regulated by a Gi- and phospholipase C-dependent pathway and not via activation of MEK/p44/p42 MAPK nor Akt/PI-3 kinase

21 January 2018

1 reference

Do phosphoinositide 3-kinases direct lymphocyte navigation?

21 January 2018

1 reference

The Bruton tyrosine kinase inhibitor PCI-32765 thwarts chronic lymphocytic leukemia cell survival and tissue homing in vitro and in vivo

21 January 2018

1 reference

The microenvironment in mature B-cell malignancies: a target for new treatment strategies

21 January 2018

1 reference

The B cell antigen receptor controls integrin activity through Btk and PLCgamma2.

21 January 2018

1 reference

Germinal center dark and light zone organization is mediated by CXCR4 and CXCR5.

21 January 2018

1 reference

A chemokine-driven positive feedback loop organizes lymphoid follicles

21 January 2018

1 reference

Neonatally induced inactivation of the vascular cell adhesion molecule 1 gene impairs B cell localization and T cell-dependent humoral immune response

21 January 2018

1 reference

Defects of B-cell lymphopoiesis and bone-marrow myelopoiesis in mice lacking the CXC chemokine PBSF/SDF-1

21 January 2018

1 reference

The role of CXCR4 in maintaining peripheral B cell compartments and humoral immunity

21 January 2018

1 reference

Chemokine requirements for B cell entry to lymph nodes and Peyer's patches.

21 January 2018

1 reference

Two independent retrotransposon insertions at the same site within the coding region of BTK.

21 January 2018

1 reference

Severe B cell deficiency in mice lacking the tec kinase family members Tec and Btk.

21 January 2018

1 reference

Defective B cell development and function in Btk-deficient mice

21 January 2018

1 reference

Impaired precursor B cell differentiation in Bruton's tyrosine kinase-deficient mice.

21 January 2018

1 reference

B-cell activation by membrane-bound antigens is facilitated by the interaction of VLA-4 with VCAM-1

21 January 2018

1 reference

Bone marrow stromal cells protect lymphoma B-cells from rituximab-induced apoptosis and targeting integrin α-4-β-1 (VLA-4) with natalizumab can overcome this resistance

21 January 2018

1 reference

Nurture versus nature: the microenvironment in chronic lymphocytic leukemia

21 January 2018

1 reference

Mantle cell lymphoma cells express high levels of CXCR4, CXCR5, and VLA-4 (CD49d): importance for interactions with the stromal microenvironment and specific targeting

21 January 2018

1 reference

Tec family kinases in T lymphocyte development and function

21 January 2018

1 reference

Ibrutinib is an irreversible molecular inhibitor of ITK driving a Th1-selective pressure in T lymphocytes

21 January 2018

1 reference

Chronic lymphocytic leukemia cells induce changes in gene expression of CD4 and CD8 T cells

21 January 2018

1 reference

Prolonged lymphocytosis during ibrutinib therapy is associated with distinct molecular characteristics and does not indicate a suboptimal response to therapy

21 January 2018

1 reference

Ibrutinib versus ofatumumab in previously treated chronic lymphoid leukemia

21 January 2018

1 reference

Idelalisib and rituximab in relapsed chronic lymphocytic leukemia

21 January 2018

1 reference

The phosphoinositide 3'-kinase delta inhibitor, CAL-101, inhibits B-cell receptor signaling and chemokine networks in chronic lymphocytic leukemia

21 January 2018

1 reference

Reconstitution of Syk function by the ZAP-70 protein tyrosine kinase

21 January 2018

1 reference

Bruton's Tyrosine Kinase and Phospholipase Cγ2 Mediate Chemokine-Controlled B Cell Migration and Homing

21 January 2018

1 reference