(Q28304165)

Highly selective hydrolytic kinetic resolution of terminal epoxides catalyzed by chiral (salen)Co(III) complexes. Practical synthesis of enantioenriched terminal epoxides and 1,2-diols

21 January 2018

1 reference

Oxygenase-catalyzed biological hydroxylations

21 January 2018

1 reference

Mechanism of action of a flavin-containing monooxygenase

21 January 2018

1 reference

Kinetic dissection of the catalytic mechanism of taurine:alpha-ketoglutarate dioxygenase (TauD) from Escherichia coli

21 January 2018

1 reference

Cytochrome P450 monooxygenases: perspectives for synthetic application

21 January 2018

1 reference

Sterol 14 alpha-demethylase, an abundant and essential mixed-function oxidase

21 January 2018

1 reference

Structure and chemistry of cytochrome P450.

21 January 2018

1 reference

Cytochrome P450: what have we learned and what are the future issues?

21 January 2018

1 reference

Crystal structures of epothilone D-bound, epothilone B-bound, and substrate-free forms of cytochrome P450epoK

21 January 2018

1 reference

Crystal structure of cytochrome P450 14 -sterol demethylase (CYP51) from Mycobacterium tuberculosis in complex with azole inhibitors

21 January 2018

1 reference

Atomic structure of Mycobacterium tuberculosis CYP121 to 1.06 A reveals novel features of cytochrome P450

21 January 2018

1 reference

Structures of human microsomal cytochrome P450 2A6 complexed with coumarin and methoxsalen

21 January 2018

1 reference

The structure of human cytochrome P450 2C9 complexed with flurbiprofen at 2.0-A resolution

21 January 2018

1 reference

Butane and propane oxidation by engineered cytochrome P450cam.

21 January 2018

1 reference

Regio- and enantioselective alkane hydroxylation with engineered cytochromes P450 BM-3.

21 January 2018

1 reference

Mechanistic enzymology of oxygen activation by the cytochromes P450.

21 January 2018

1 reference

High-resolution crystal structure of cytochrome P450cam

21 January 2018

1 reference

Bacterial cytochromes P-450.

21 January 2018

1 reference

Spin-state changes in cytochrome P-450cam on binding of specific substrates

21 January 2018

1 reference

Coupling of spin, substrate, and redox equilibriums in cytochrome P450

21 January 2018

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Redox control of the catalytic cycle of flavocytochrome P-450 BM3.

21 January 2018

1 reference

The binding to oxidised cytochromes P-450 and inhibition of mixed-function oxidases by aryl-substituted benzimidazoles and related compounds

21 January 2018

1 reference

Thirty years of microbial P450 monooxygenase research: peroxo-heme intermediates--the central bus station in heme oxygenase catalysis

21 January 2018

1 reference

Cytochrome p450 compound I.

21 January 2018

1 reference

Hydroxylation of camphor by reduced oxy-cytochrome P450cam: mechanistic implications of EPR and ENDOR studies of catalytic intermediates in native and mutant enzymes

21 January 2018

1 reference

Multiple mechanisms and multiple oxidants in P450-catalyzed hydroxylations

21 January 2018

1 reference

An A245T mutation conveys on cytochrome P450eryF the ability to oxidize alternative substrates

21 January 2018

1 reference

A transmissible plasmid controlling camphor oxidation in Pseudomonas putida

21 January 2018

1 reference

Function of Cyp11a1 in animal models

21 January 2018

1 reference

CYP17- and CYP11B-dependent steroid hydroxylases as drug development targets

21 January 2018

1 reference

The human steroid hydroxylases CYP1B1 and CYP11B2

21 January 2018

1 reference

Adrenodoxin reductase-adrenodoxin complex structure suggests electron transfer path in steroid biosynthesis

21 January 2018

1 reference

Crystal structures of adrenodoxin reductase in complex with NADP+ and NADPH suggesting a mechanism for the electron transfer of an enzyme family

21 January 2018

1 reference

Adrenodoxin: structure, stability, and electron transfer properties

21 January 2018

1 reference

The tertiary structure of full-length bovine adrenodoxin suggests functional dimers

21 January 2018

1 reference

Characterization of the protein expressed in Escherichia coli by a recombinant plasmid containing the Bacillus megaterium cytochrome P-450BM-3 gene.

21 January 2018

1 reference

Cytosine deaminase gene as a positive selection marker

21 January 2018

1 reference

Probing electron transfer in flavocytochrome P-450 BM3 and its component domains.

21 January 2018

1 reference

Relaxation kinetics of cytochrome P450 reductase: internal electron transfer is limited by conformational change and regulated by coenzyme binding.

21 January 2018

1 reference

Engineering of a functional human NADH-dependent cytochrome P450 system

21 January 2018

1 reference

Kinetic mechanism for the model reaction of NADPH-cytochrome P450 oxidoreductase with cytochrome c.

21 January 2018

1 reference

Interflavin electron transfer in human cytochrome P450 reductase is enhanced by coenzyme binding. Relaxation kinetic studies with coenzyme analogues

21 January 2018

1 reference

P450 BM3: the very model of a modern flavocytochrome

21 January 2018

1 reference

Mechanistic studies with N-benzyl-1-aminobenzotriazole-inactivated CYP2B1: differential effects on the metabolism of 7-ethoxy-4-(trifluoromethyl)coumarin, testosterone, and benzphetamine

21 January 2018

1 reference

Role of LYS271 and LYS279 residues in the interaction of cytochrome P4501A1 with NADPH-cytochrome P450 reductase

21 January 2018

1 reference

Phenylalanine 393 exerts thermodynamic control over the heme of flavocytochrome P450 BM3.

21 January 2018

1 reference

Electron transfer in flavocytochrome P450 BM3: kinetics of flavin reduction and oxidation, the role of cysteine 999, and relationships with mammalian cytochrome P450 reductase

21 January 2018

1 reference

Ralstonia metallidurans, a bacterium specifically adapted to toxic metals: towards a catalogue of metal-responsive genes

21 January 2018

1 reference

The complete genome sequence of the gram-positive bacterium Bacillus subtilis

21 January 2018

1 reference

Expression, purification, and characterization of Bacillus subtilis cytochromes P450 CYP102A2 and CYP102A3: flavocytochrome homologues of P450 BM3 from Bacillus megaterium

21 January 2018

1 reference

Inhibitory effects of 9-beta-D-xylofuranosyladenine 5'-triphosphate on DNA-dependent RNA polymerase I and II from cherry salmon (Oncorhynchus masou).

21 January 2018

1 reference

Fusarium oxysporum fatty-acid subterminal hydroxylase (CYP505) is a membrane-bound eukaryotic counterpart of Bacillus megaterium cytochrome P450BM3.

21 January 2018

1 reference

Characterization of four clustered and coregulated genes associated with fumonisin biosynthesis in Fusarium verticillioides

21 January 2018

1 reference

A novel class of self-sufficient cytochrome P450 monooxygenases in prokaryotes.

21 January 2018

1 reference

A self-sufficient cytochrome p450 with a primary structural organization that includes a flavin domain and a [2Fe-2S] redox center

21 January 2018

1 reference

Analysis of the domain properties of the novel cytochrome P450 RhF.

21 January 2018

1 reference

Cloning, expression, and characterization of a self-sufficient cytochrome P450 monooxygenase from Rhodococcus ruber DSM 44319.

21 January 2018

1 reference

Carbon-carbon bond cleavage by cytochrome p450(BioI)(CYP107H1).

21 January 2018

1 reference

Expression, purification and characterization of cytochrome P450 Biol: a novel P450 involved in biotin synthesis in Bacillus subtilis

21 January 2018

1 reference

Expression, purification and characterisation of a Bacillus subtilis ferredoxin: a potential electron transfer donor to cytochrome P450 BioI.

21 January 2018

1 reference

Thermodynamic and biophysical characterization of cytochrome P450 BioI from Bacillus subtilis.

21 January 2018

1 reference

Expression and characterization of the two flavodoxin proteins of Bacillus subtilis, YkuN and YkuP: biophysical properties and interactions with cytochrome P450 BioI.

21 January 2018

1 reference

Crystal structure of P450cin in a complex with its substrate, 1,8-cineole, a close structural homologue to D-camphor, the substrate for P450cam.

21 January 2018

1 reference

NADPH-flavodoxin reductase and flavodoxin from Escherichia coli: characteristics as a soluble microsomal P450 reductase.

21 January 2018

1 reference

A novel sterol 14alpha-demethylase/ferredoxin fusion protein (MCCYP51FX) from Methylococcus capsulatus represents a new class of the cytochrome P450 superfamily

21 January 2018

1 reference

Antifungal agents: mechanisms of action

21 January 2018

1 reference

Biophysical characterization of the sterol demethylase P450 from Mycobacterium tuberculosis, its cognate ferredoxin, and their interactions

21 January 2018

1 reference

Characterization and catalytic properties of the sterol 14alpha-demethylase from Mycobacterium tuberculosis

21 January 2018

1 reference

CYP121, CYP51 and associated redox systems in Mycobacterium tuberculosis: towards deconvoluting enzymology of P450 systems in a human pathogen

21 January 2018

1 reference

An explosive-degrading cytochrome P450 activity and its targeted application for the phytoremediation of RDX.

21 January 2018

1 reference

CYP119 plus a Sulfolobus tokodaii strain 7 ferredoxin and 2-oxoacid:ferredoxin oxidoreductase constitute a high-temperature cytochrome P450 catalytic system

21 January 2018

1 reference

The Sulfolobus solfataricus electron donor partners of thermophilic CYP119: an unusual non-NAD(P)H-dependent cytochrome P450 system

21 January 2018

1 reference

Acyl-CoA dehydrogenases. A mechanistic overview

21 January 2018

1 reference

Cytochrome P450 4A fatty acid omega hydroxylases

21 January 2018

1 reference

Heme-Containing Oxygenases

21 January 2018

1 reference

Cytochromes P450 as versatile biocatalysts

21 January 2018

1 reference

CYP51--the omnipotent P450.

21 January 2018

1 reference

Human cytochrome P-450PA (P-450IA2), the phenacetin O-deethylase, is primarily responsible for the hepatic 3-demethylation of caffeine and N-oxidation of carcinogenic arylamines

21 January 2018

1 reference

Screening for endogenous substrates reveals that CYP2D6 is a 5-methoxyindolethylamine O-demethylase

21 January 2018

1 reference

Androgen biosynthesis from cholesterol to DHEA.

21 January 2018

1 reference

Enantioselective epoxidation of terminal alkenes to (R)- and (S)-epoxides by engineered cytochromes P450 BM-3.

21 January 2018

1 reference

formation of 9,10-epoxypalmitate and 9,10-dihydroxypalmitate from palmitoleic acid by a soluble system from Bacillusmegaterium

21 January 2018

1 reference

Oxidation of trichloroethylene by liver microsomal cytochrome P-450: evidence for chlorine migration in a transition state not involving trichloroethylene oxide

21 January 2018

1 reference

Olefin oxidation by cytochrome P-450: evidence for group migration in catalytic intermediates formed with vinylidene chloride and trans-1-phenyl-1-butene

21 January 2018

1 reference

Multi-state epoxidation of ethene by cytochrome P450: a quantum chemical study

21 January 2018

1 reference

Stereospecific oxidation by compound I of cytochrome P450 does not proceed in a concerted synchronous manner

21 January 2018

1 reference

Protein engineering of cytochrome p450(cam) (CYP101) for the oxidation of polycyclic aromatic hydrocarbons

21 January 2018

1 reference

Oxidation of polychlorinated benzenes by genetically engineered CYP101 (cytochrome P450(cam)).

21 January 2018

1 reference

Laboratory evolution of peroxide-mediated cytochrome P450 hydroxylation

21 January 2018

1 reference

Critical role of the residue size at position 87 in H2O2- dependent substrate hydroxylation activity and H2O2 inactivation of cytochrome P450BM-3.

21 January 2018

1 reference

Substrate recognition and molecular mechanism of fatty acid hydroxylation by cytochrome P450 from Bacillus subtilis. Crystallographic, spectroscopic, and mutational studies

21 January 2018

1 reference

Nitric oxide reductase (P450nor) from Fusarium oxysporum

21 January 2018

1 reference

A possible role of NADPH-dependent cytochrome P450nor isozyme in glycolysis under denitrifying conditions

21 January 2018

1 reference

Purification and cDNA cloning of nitric oxide reductase cytochrome P450nor (CYP55A4) from Trichosporon cutaneum.

21 January 2018

1 reference

Structural evidence for direct hydride transfer from NADH to cytochrome P450nor

21 January 2018

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Spectroscopic and kinetic studies on reaction of cytochrome P450nor with nitric oxide. Implication for its nitric oxide reduction mechanism

21 January 2018

1 reference

Uncommon P450-catalyzed reactions

21 January 2018

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Biodehalogenation: reactions of cytochrome P-450 with polyhalomethanes.

21 January 2018

1 reference

Purification of an allene oxide synthase and identification of the enzyme as a cytochrome P-450.

21 January 2018

1 reference

Cloning, molecular and functional characterization of Arabidopsis thaliana allene oxide synthase (CYP 74), the first enzyme of the octadecanoid pathway to jasmonates

21 January 2018

1 reference

The lipoxygenase pathway.

21 January 2018

1 reference

Molecular cloning of human platelet thromboxane A synthase

21 January 2018

1 reference

Products, kinetics, and substrate specificity of homogeneous thromboxane synthase from human platelets: development of a novel enzyme assay

21 January 2018

1 reference

Crystal structure of hemoprotein domain of P450BM-3, a prototype for microsomal P450's

21 January 2018

1 reference

Crystal structure of constitutive endothelial nitric oxide synthase: a paradigm for pterin function involving a novel metal center

21 January 2018

1 reference

Structure of a nitric oxide synthase heme protein from Bacillus subtilis

21 January 2018

1 reference

P450 superfamily: update on new sequences, gene mapping, accession numbers and nomenclature.

21 January 2018

1 reference

The structure of nitric oxide synthase oxygenase domain and inhibitor complexes

21 January 2018

1 reference

Neutral thiol as a proximal ligand to ferrous heme iron: implications for heme proteins that lose cysteine thiolate ligation on reduction

21 January 2018

1 reference

EpoK, a cytochrome P450 involved in biosynthesis of the anticancer agents epothilones A and B. Substrate-mediated rescue of a P450 enzyme

21 January 2018

1 reference

Structural and spectroscopic analysis of the F393H mutant of flavocytochrome P450 BM3

21 January 2018

1 reference

The cytochrome P450 gene family CYP157 does not contain EXXR in the K-helix reducing the absolute conserved P450 residues to a single cysteine.

21 January 2018

1 reference

Mammalian microsomal cytochrome P450 monooxygenase: structural adaptations for membrane binding and functional diversity

21 January 2018

1 reference

The structure of the cytochrome p450BM-3 haem domain complexed with the fatty acid substrate, palmitoleic acid

21 January 2018

1 reference

Pivotal role of water in the mechanism of P450BM-3

21 January 2018

1 reference

Crystal structure of substrate-free Pseudomonas putida cytochrome P-450

21 January 2018

1 reference

Folding requirements are different between sterol 14alpha-demethylase (CYP51) from Mycobacterium tuberculosis and human or fungal orthologs

21 January 2018

1 reference

Uncoupling of the cytochrome P-450cam monooxygenase reaction by a single mutation, threonine-252 to alanine or valine: possible role of the hydroxy amino acid in oxygen activation

21 January 2018

1 reference

The role of Thr268 in oxygen activation of cytochrome P450BM-3

21 January 2018

1 reference

Substrate-assisted catalysis in cytochrome P450eryF.

21 January 2018

1 reference

The catalytic pathway of cytochrome p450cam at atomic resolution

21 January 2018

1 reference

Structural diversity of human xenobiotic-metabolizing cytochrome P450 monooxygenases

21 January 2018

1 reference

Crystal structures of human cytochrome P450 3A4 bound to metyrapone and progesterone

21 January 2018

1 reference

The structure of human microsomal cytochrome P450 3A4 determined by X-ray crystallography to 2.05-A resolution

21 January 2018

1 reference

Resolution of two substrate-binding sites in an engineered cytochrome P450eryF bearing a fluorescent probe

21 January 2018

1 reference

Structural basis for ligand promiscuity in cytochrome P450 3A4.

21 January 2018

1 reference

An open conformation of mammalian cytochrome P450 2B4 at 1.6-Å resolution

21 January 2018

1 reference

Structure of mammalian cytochrome P450 2B4 complexed with 4-(4-chlorophenyl)imidazole at 1.9-A resolution: insight into the range of P450 conformations and the coordination of redox partner binding

21 January 2018

1 reference

Structure of microsomal cytochrome P450 2B4 complexed with the antifungal drug bifonazole: insight into P450 conformational plasticity and membrane interaction.

21 January 2018

1 reference

Thermophilic cytochrome P450 (CYP119) from Sulfolobus solfataricus: high resolution structure and functional properties

21 January 2018

1 reference

Aromatic stacking as a determinant of the thermal stability of CYP119 from Sulfolobus solfataricus

21 January 2018

1 reference

Preliminary characterization and crystal structure of a thermostable cytochrome P450 from Thermus thermophilus

21 January 2018

1 reference

P450BM-3 and other inducible bacterial P450 cytochromes: biochemistry and regulation

21 January 2018

1 reference

A thermodynamic model of regulation: modulation of redox equilibria in camphor monoxygenase

21 January 2018

1 reference

NMR studies of substrate binding to cytochrome P450 BM3: comparisons to cytochrome P450 cam.

21 January 2018

1 reference

Flavocytochrome P450 BM3 mutant A264E undergoes substrate-dependent formation of a novel heme iron ligand set.

21 January 2018

1 reference

A single mutation in cytochrome P450 BM3 induces the conformational rearrangement seen upon substrate binding in the wild-type enzyme.

21 January 2018

1 reference

Structural and spectroscopic characterization of P450 BM3 mutants with unprecedented P450 heme iron ligand sets. New heme ligation states influence conformational equilibria in P450 BM3.

21 January 2018

1 reference

Crystal structure of putidaredoxin reductase from Pseudomonas putida, the final structural component of the cytochrome P450cam monooxygenase

21 January 2018

1 reference

Crystal Structure of Putidaredoxin, the [2Fe–2S] Component of the P450cam Monooxygenase System from Pseudomonas putida

21 January 2018

1 reference

Molecular recognition and electron transfer in mitochondrial steroid hydroxylase systems

21 January 2018

1 reference

Putidaredoxin-to-cytochrome P450cam electron transfer: differences between the two reductive steps required for catalysis

21 January 2018

1 reference

Structural basis for isozyme-specific regulation of electron transfer in nitric-oxide synthase.

21 January 2018

1 reference

Structure of a cytochrome P450-redox partner electron-transfer complex

21 January 2018

1 reference

The dimeric form of flavocytochrome P450 BM3 is catalytically functional as a fatty acid hydroxylase.

21 January 2018

1 reference

Domain swapping in inducible nitric-oxide synthase. Electron transfer occurs between flavin and heme groups located on adjacent subunits in the dimer.

21 January 2018

1 reference

NADPH-cytochrome P450 oxidoreductase. Structural basis for hydride and electron transfer

21 January 2018

1 reference

Switching pyridine nucleotide specificity in P450 BM3: mechanistic analysis of the W1046H and W1046A enzymes

21 January 2018

1 reference

The heme monooxygenase cytochrome P450cam can be engineered to oxidize ethane to ethanol

21 January 2018

1 reference

Molecular recognition in cytochrome P-450: mechanism for the control of uncoupling reactions.

21 January 2018

1 reference

Protein engineering of Bacillus megaterium CYP102. The oxidation of polycyclic aromatic hydrocarbons

21 January 2018

1 reference

Laboratory evolution of a soluble, self-sufficient, highly active alkane hydroxylase

21 January 2018

1 reference

Direct conversion of ethane to ethanol by engineered cytochrome P450 BM3.

21 January 2018

1 reference

A self-sufficient peroxide-driven hydroxylation biocatalyst

21 January 2018

1 reference

Protein stability promotes evolvability

21 January 2018

1 reference

Preparation of human metabolites of propranolol using laboratory-evolved bacterial cytochromes P450.

21 January 2018

1 reference

Laboratory evolution of cytochrome p450 BM-3 monooxygenase for organic cosolvents

21 January 2018

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Proximal cysteine residue is essential for the enzymatic activities of cytochrome P450cam.

21 January 2018

1 reference

Biotransformation of the sesquiterpene (+)-valencene by cytochrome P450cam and P450BM-3.

21 January 2018

1 reference

A single amino acid substitution (Leu160His) in cytochrome P450 CYP2A6 causes switching from 7-hydroxylation to 3-hydroxylation of coumarin

21 January 2018

1 reference

Engineering microsomal cytochrome P450 2C5 to be a soluble, monomeric enzyme. Mutations that alter aggregation, phospholipid dependence of catalysis, and membrane binding

21 January 2018

1 reference

Engineering cytochrome P-450s: chimeric enzymes

21 January 2018

1 reference

High-level expression in Escherichia coli of enzymatically active fusion proteins containing the domains of mammalian cytochromes P450 and NADPH-P450 reductase flavoprotein

21 January 2018

1 reference

Human cytochrome P450 3A4: enzymatic properties of a purified recombinant fusion protein containing NADPH-P450 reductase

21 January 2018

1 reference

Putidaredoxin reductase-putidaredoxin-cytochrome p450cam triple fusion protein. Construction of a self-sufficient Escherichia coli catalytic system.

21 January 2018

1 reference

Electrocatalytically driven omega-hydroxylation of fatty acids using cytochrome P450 4A1

21 January 2018

1 reference

Self-Assembly of Discoidal Phospholipid Bilayer Nanoparticles with Membrane Scaffold Proteins

21 January 2018

1 reference

Directed self-assembly of monodisperse phospholipid bilayer Nanodiscs with controlled size

21 January 2018

1 reference

Co-incorporation of heterologously expressed Arabidopsis cytochrome P450 and P450 reductase into soluble nanoscale lipid bilayers

21 January 2018

1 reference

Homotropic cooperativity of monomeric cytochrome P450 3A4 in a nanoscale native bilayer environment

21 January 2018

1 reference

Kinetics of dithionite-dependent reduction of cytochrome P450 3A4: heterogeneity of the enzyme caused by its oligomerization.

21 January 2018

1 reference

Formation of compound I by photo-oxidation of compound II.

21 January 2018

1 reference

Hydroxylation by the hydroperoxy-iron species in cytochrome P450 enzymes

21 January 2018

1 reference

Epoxidation of olefins by cytochrome P450: evidence from site-specific mutagenesis for hydroperoxo-iron as an electrophilic oxidant

21 January 2018

1 reference

Searching for the second oxidant in the catalytic cycle of cytochrome P450: a theoretical investigation of the iron(III)-hydroperoxo species and its epoxidation pathways

21 January 2018

1 reference

Isolation and structure determination of novamethymycin, a new bioactive metabolite of the methymycin biosynthetic pathway in Streptomyces venezuelae

21 January 2018

1 reference

Neopikromycin and novapikromycin from the pikromycin biosynthetic pathway of Streptomyces venezuelae.

21 January 2018

1 reference

The structural basis for substrate anchoring, active site selectivity, and product formation by P450 PikC from Streptomyces venezuelae

21 January 2018

1 reference

Crystal structure and refinement of cytochrome P450terp at 2.3 A resolution

21 January 2018

1 reference

Preliminary crystallographic analysis of an enzyme involved in erythromycin biosynthesis: cytochrome P450eryF.

21 January 2018

1 reference

Crystal structure of nitric oxide reductase from denitrifying fungus Fusarium oxysporum

21 January 2018

1 reference

Crystal structure of a thermophilic cytochrome P450 from the archaeon Sulfolobus solfataricus

21 January 2018

1 reference

Crystal structure of OxyB, a cytochrome P450 implicated in an oxidative phenol coupling reaction during vancomycin biosynthesis

21 January 2018

1 reference

The 1.92-A structure of Streptomyces coelicolor A3(2) CYP154C1. A new monooxygenase that functionalizes macrolide ring systems

21 January 2018

1 reference

Crystal structure of human cytochrome P450 2C9 with bound warfarin

21 January 2018

1 reference

Crystal structure of OxyC, a cytochrome P450 implicated in an oxidative C-C coupling reaction during vancomycin biosynthesis

21 January 2018

1 reference

Comparison of the 1.85 A structure of CYP154A1 from Streptomyces coelicolor A3(2) with the closely related CYP154C1 and CYPs from antibiotic biosynthetic pathways

21 January 2018

1 reference

Structure of human microsomal cytochrome P450 2C8. Evidence for a peripheral fatty acid binding site

21 January 2018

1 reference

Structure and direct electrochemistry of cytochrome P450 from the thermoacidophilic crenarchaeon, Sulfolobus tokodaii strain 7.

21 January 2018

1 reference

Binding of two flaviolin substrate molecules, oxidative coupling, and crystal structure of Streptomyces coelicolor A3(2) cytochrome P450 158A2

21 January 2018

1 reference

Crystal structure of human cytochrome P450 2D6

21 January 2018

1 reference

Crystal structure of the human prostacyclin synthase

21 January 2018

1 reference

The 1.5 A resolution crystal structure of [Fe3S4]-ferredoxin from the hyperthermophilic archaeon Pyrococcus furiosus.

21 January 2018

1 reference

Crystal structures of the key anaerobic enzyme pyruvate:ferredoxin oxidoreductase, free and in complex with pyruvate

21 January 2018

1 reference

Site-directed mutagenesis of Azotobacter vinelandii ferredoxin I: [Fe-S] cluster-driven protein rearrangement

21 January 2018

1 reference

Crystal structures of medium-chain acyl-CoA dehydrogenase from pig liver mitochondria with and without substrate

21 January 2018

1 reference

Cholesterol-metabolizing cytochromes P450

21 January 2018

1 reference

Metabolic activation of polycyclic aromatic hydrocarbons to carcinogens by cytochromes P450 1A1 and 1B1.

21 January 2018

1 reference

Molecular basis for the differences in lidocaine binding and regioselectivity of oxidation by cytochromes P450 2B1 and 2B2

21 January 2018

1 reference

Stereoselective hydroxylation of an achiral cyclopentanecarboxylic acid derivative using engineered P450s BM-3.

21 January 2018

1 reference

Evaluation of alkoxyresorufins as fluorescent substrates for cytochrome P450 BM3 and site-directed mutants.

21 January 2018

1 reference

A P450 BM-3 mutant hydroxylates alkanes, cycloalkanes, arenes and heteroarenes

21 January 2018

1 reference

A screening system for the directed evolution of epoxygenases: importance of position 184 in P450 BM3 for stereoselective styrene epoxidation.

21 January 2018

1 reference

Active site mutations of cytochrome p450cam alter the binding, coupling, and oxidation of the foreign substrates (R)- and (s)-2-ethylhexanol

21 January 2018

1 reference

Characterization of the P450 monooxygenase NysL, responsible for C-10 hydroxylation during biosynthesis of the polyene macrolide antibiotic nystatin in Streptomyces noursei.

21 January 2018

1 reference

Role of the cytochrome P450 NocL in nocardicin A biosynthesis

21 January 2018

1 reference

The biosynthesis of vancomycin-type glycopeptide antibiotics--a model for oxidative side-chain cross-linking by oxygenases coupled to the action of peptide synthetases

21 January 2018

1 reference

Amphotericin biosynthesis in Streptomyces nodosus: deductions from analysis of polyketide synthase and late genes

21 January 2018

1 reference

Biosynthesis of deoxyamphotericins and deoxyamphoteronolides by engineered strains of Streptomyces nodosus

21 January 2018

1 reference

Biosynthesis of amphotericin derivatives lacking exocyclic carboxyl groups

21 January 2018

1 reference

Rapid identification of cytochrome P450cam variants by in vivo screening of active site libraries

21 January 2018

1 reference

The catalytic mechanism of cytochrome P450 BM3 involves a 6 Å movement of the bound substrate on reduction

21 January 2018

1 reference

A Single Mutation in Cytochrome P450 BM3 Changes Substrate Orientation in a Catalytic Intermediate and the Regiospecificity of Hydroxylation†

21 January 2018

1 reference

Selectivity of Polycyclic Inhibitors for Human Cytochrome P450s 1A1, 1A2, and 1B1

21 January 2018

1 reference