(Q34245261)

31 July 2017

title

Pathogenesis of human B cell lymphomas (English)

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31 July 2017

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Arthur L Shaffer

1

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31 July 2017

Ryan M Young

series ordinal

2

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31 July 2017

Louis M Staudt

series ordinal

3

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31 July 2017

publication date

6 January 2012

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Annual Review of Immunology

31 July 2017

published in

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31 July 2017

volume

30

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31 July 2017

page(s)

565-610

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B cell antigen receptor signaling 101.

31 July 2017

cites work

1 reference

12 December 2020

Gene expression profiling of hairy cell leukemia reveals a phenotype related to memory B cells with altered expression of chemokine and adhesion receptors

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12 December 2020

p16/INK4a and p15/INK4b gene methylation and absence of p16/INK4a mRNA and protein expression in Burkitt's lymphoma

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12 December 2020

Chromatin modifications and their function

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12 December 2020

Deregulated BCL6 expression recapitulates the pathogenesis of human diffuse large B cell lymphomas in mice

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12 December 2020

The miR-17-92 cluster of microRNAs confers tumorigenicity by inhibiting oncogene-induced senescence

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12 December 2020

Biology and treatment of Burkitt's lymphoma

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12 December 2020

IAPs: from caspase inhibitors to modulators of NF-kappaB, inflammation and cancer

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12 December 2020

CARMA1, BCL-10 and MALT1 in lymphocyte development and activation.

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12 December 2020

Genomic amplification and oncogenic properties of the GASC1 histone demethylase gene in breast cancer

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12 December 2020

The phosphoinositide 3'-kinase delta inhibitor, CAL-101, inhibits B-cell receptor signaling and chemokine networks in chronic lymphocytic leukemia

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12 December 2020

BCR-mediated uptake of antigen linked to TLR9 ligand stimulates B-cell proliferation and antigen-specific plasma cell formation

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12 December 2020

Gene expression profiling of B cell chronic lymphocytic leukemia reveals a homogeneous phenotype related to memory B cells.

1 reference

12 December 2020

BLIMP1 is a tumor suppressor gene frequently disrupted in activated B cell-like diffuse large B cell lymphoma

1 reference

12 December 2020

miR-15 and miR-16 induce apoptosis by targeting BCL2

1 reference

12 December 2020

Noncanonical NF-kappaB activation requires coordinated assembly of a regulatory complex of the adaptors cIAP1, cIAP2, TRAF2 and TRAF3 and the kinase NIK.

1 reference

12 December 2020

Specific peptide interference reveals BCL6 transcriptional and oncogenic mechanisms in B-cell lymphoma cells.

1 reference

12 December 2020

The lymph node microenvironment promotes B-cell receptor signaling, NF-kappaB activation, and tumor proliferation in chronic lymphocytic leukemia

1 reference

12 December 2020

A purine scaffold Hsp90 inhibitor destabilizes BCL-6 and has specific antitumor activity in BCL-6-dependent B cell lymphomas

1 reference

12 December 2020

Myc-mediated repression of microRNA-34a promotes high-grade transformation of B-cell lymphoma by dysregulation of FoxP1

1 reference

12 December 2020

Cancer. Addiction to oncogenes--the Achilles heal of cancer

1 reference

12 December 2020

FOXP1, a gene highly expressed in a subset of diffuse large B-cell lymphoma, is recurrently targeted by genomic aberrations

1 reference

12 December 2020

Interleukin 13 and interleukin 13 receptor are frequently expressed by Hodgkin and Reed-Sternberg cells of Hodgkin lymphoma

1 reference

12 December 2020

BMI-1 gene amplification and overexpression in hematological malignancies occur mainly in mantle cell lymphomas

1 reference

12 December 2020

Recruitment of P-TEFb for stimulation of transcriptional elongation by the bromodomain protein Brd4

1 reference

12 December 2020

The BCL6 transcriptional program features repression of multiple oncogenes in primary B cells and is deregulated in DLBCL.

1 reference

12 December 2020

p300/CBP proteins: HATs for transcriptional bridges and scaffolds

1 reference

12 December 2020

Inhibition of Mutated, Activated BRAF in Metastatic Melanoma

1 reference

12 December 2020

BCL6 repression of EP300 in human diffuse large B cell lymphoma cells provides a basis for rational combinatorial therapy

1 reference

12 December 2020

Cleavage of NIK by the API2-MALT1 fusion oncoprotein leads to noncanonical NF-kappaB activation

1 reference

12 December 2020

Src-family kinases in B-cell development and signaling

1 reference

12 December 2020

The B cell antigen receptor and overexpression of MYC can cooperate in the genesis of B cell lymphomas

1 reference

12 December 2020

Deregulation of MUM1/IRF4 by chromosomal translocation in multiple myeloma

1 reference

12 December 2020

Crystal structure of PU.1/IRF-4/DNA ternary complex

1 reference

12 December 2020

Coexpression of CD58 or CD48 with intercellular adhesion molecule 1 on target cells enhances adhesion of resting NK cells.

1 reference

12 December 2020

Ig V gene mutation status and CD38 expression as novel prognostic indicators in chronic lymphocytic leukemia

1 reference

12 December 2020

Infection-associated lymphomas derived from marginal zone B cells: a model of antigen-driven lymphoproliferation

1 reference

12 December 2020

Promiscuous mutations activate the noncanonical NF-kappaB pathway in multiple myeloma.

1 reference

12 December 2020

CD2 sets quantitative thresholds in T cell activation

1 reference

12 December 2020

Murine B cell response to TLR7 ligands depends on an IFN-beta feedback loop

1 reference

12 December 2020

A revised picture of the E2F transcriptional network and RB function

1 reference

12 December 2020

Differential efficacy of bortezomib plus chemotherapy within molecular subtypes of diffuse large B-cell lymphoma

1 reference

12 December 2020

Visualization of Syk-antigen receptor interactions using green fluorescent protein: differential roles for Syk and Lyn in the regulation of receptor capping and internalization

1 reference

12 December 2020

The structural basis for the recognition of acetylated histone H4 by the bromodomain of histone acetyltransferase gcn5p

1 reference

12 December 2020

Spi-B inhibits human plasma cell differentiation by repressing BLIMP1 and XBP-1 expression

1 reference

12 December 2020

The use of molecular profiling to predict survival after chemotherapy for diffuse large-B-cell lymphoma

1 reference

12 December 2020

Mutation of BCL-6 gene in normal B cells by the process of somatic hypermutation of Ig genes

1 reference

12 December 2020

The molecular pathogenesis of primary mediastinal large B-cell lymphoma

1 reference

12 December 2020

Direct regulation of an oncogenic micro-RNA cluster by E2F transcription factors

1 reference

12 December 2020

Overexpression of an enzymically inactive interleukin-1-receptor-associated kinase activates nuclear factor-kappaB

1 reference

12 December 2020

MTA3 and the Mi-2/NuRD complex regulate cell fate during B lymphocyte differentiation

1 reference

12 December 2020

Effect of PU.1 phosphorylation on interaction with NF-EM5 and transcriptional activation

1 reference

12 December 2020

The BH3 mimetic ABT-737 targets selective Bcl-2 proteins and efficiently induces apoptosis via Bak/Bax if Mcl-1 is neutralized.

1 reference

12 December 2020

Acquired TNFRSF14 mutations in follicular lymphoma are associated with worse prognosis.

1 reference

12 December 2020

Unphosphorylated STAT3 accumulates in response to IL-6 and activates transcription by binding to NFkappaB

1 reference

12 December 2020

Reversal of histone lysine trimethylation by the JMJD2 family of histone demethylases

1 reference

12 December 2020

Distinct types of diffuse large B-cell lymphoma identified by gene expression profiling

1 reference

12 December 2020

Developmental acquisition of the Lyn-CD22-SHP-1 inhibitory pathway promotes B cell tolerance

1 reference

12 December 2020

IAPs contain an evolutionarily conserved ubiquitin-binding domain that regulates NF-kappaB as well as cell survival and oncogenesis

1 reference

12 December 2020

Frequent mutation of histone-modifying genes in non-Hodgkin lymphoma

1 reference

12 December 2020

Aberrant immunoglobulin class switch recombination and switch translocations in activated B cell-like diffuse large B cell lymphoma

1 reference

12 December 2020

Recurrent numerical aberrations of JAK2 and deregulation of the JAK2-STAT cascade in lymphomas

1 reference

12 December 2020

T-cell receptor-induced JNK activation requires proteolytic inactivation of CYLD by MALT1.

1 reference

12 December 2020

Signatures of the immune response

1 reference

12 December 2020

Bcl-6 and NF-kappaB cistromes mediate opposing regulation of the innate immune response.

1 reference

12 December 2020

Molecular pathogenesis of non-Hodgkin's lymphoma: the role of Bcl-6

1 reference

12 December 2020

Inhibition of MALT1 protease activity is selectively toxic for activated B cell-like diffuse large B cell lymphoma cells

1 reference

12 December 2020

Small molecule inhibitors of IkappaB kinase are selectively toxic for subgroups of diffuse large B-cell lymphoma defined by gene expression profiling.

1 reference

12 December 2020

B lymphocytes differentially use the Rel and nuclear factor kappaB1 (NF-kappaB1) transcription factors to regulate cell cycle progression and apoptosis in quiescent and mitogen-activated cells

1 reference

12 December 2020

Regulation of adaptive immunity by the innate immune system

1 reference

12 December 2020

The ectodomain of Toll-like receptor 9 is cleaved to generate a functional receptor.

1 reference

12 December 2020

Gene regulatory networks that orchestrate the development of B lymphocyte precursors

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12 December 2020

The B-cell receptor of a hepatitis C virus (HCV)-associated non-Hodgkin lymphoma binds the viral E2 envelope protein, implicating HCV in lymphomagenesis

1 reference

12 December 2020

Blimp-1-dependent repression of Pax-5 is required for differentiation of B cells to immunoglobulin M-secreting plasma cells

1 reference

12 December 2020

BCL6 represses CHEK1 and suppresses DNA damage pathways in normal and malignant B-cells

1 reference

12 December 2020

Gain of chromosome arm 9p is characteristic of primary mediastinal B-cell lymphoma (MBL): comprehensive molecular cytogenetic analysis and presentation of a novel MBL cell line

1 reference

12 December 2020

Mutations of CARD11 but not TNFAIP3 may activate the NF-kappaB pathway in primary CNS lymphoma

1 reference

12 December 2020

Therapeutic targeting of the BCL6 oncogene for diffuse large B-cell lymphomas

1 reference

12 December 2020

Enhancement and suppression of signaling by the conserved tail of IgG memory-type B cell antigen receptors

1 reference

12 December 2020

PI3 kinase signals BCR-dependent mature B cell survival

1 reference

12 December 2020

Crystallization and characterization of PU.1/IRF-4/DNA ternary complex

1 reference

12 December 2020

Targeting protein kinases for the development of anti-inflammatory drugs

1 reference

12 December 2020

The BCL6 proto-oncogene suppresses p53 expression in germinal-centre B cells

1 reference

12 December 2020

Navitoclax, a targeted high-affinity inhibitor of BCL-2, in lymphoid malignancies: a phase 1 dose-escalation study of safety, pharmacokinetics, pharmacodynamics, and antitumour activity

1 reference

12 December 2020

Lymphoproliferative disease and autoimmunity in mice with increased miR-17-92 expression in lymphocytes

1 reference

12 December 2020

Selective utilization of Toll-like receptor and MyD88 signaling in B cells for enhancement of the antiviral germinal center response

1 reference

12 December 2020

Genomic imbalances including amplification of the tyrosine kinase gene JAK2 in CD30+ Hodgkin cells

1 reference

12 December 2020

The Bruton tyrosine kinase inhibitor PCI-32765 blocks B-cell activation and is efficacious in models of autoimmune disease and B-cell malignancy

1 reference

12 December 2020

SYK-dependent tonic B-cell receptor signaling is a rational treatment target in diffuse large B-cell lymphoma

1 reference

12 December 2020

The proteolytic activity of the paracaspase MALT1 is key in T cell activation

1 reference

12 December 2020

Follicular lymphoma-like B cells in healthy individuals: a novel intermediate step in early lymphomagenesis

1 reference

12 December 2020

AID is required for germinal center-derived lymphomagenesis

1 reference

12 December 2020

Corepressor SMRT binds the BTB/POZ repressing domain of the LAZ3/BCL6 oncoprotein

1 reference

12 December 2020

Ig-α Cytoplasmic Truncation Renders Immature B Cells More Sensitive to Antigen Contact

1 reference

12 December 2020

Antigen receptor signaling to NF-kappaB via CARMA1, BCL10, and MALT1.

1 reference

12 December 2020

Disruption of the Bcl6 gene results in an impaired germinal center formation

1 reference

12 December 2020

Alterations of a zinc finger-encoding gene, BCL-6, in diffuse large-cell lymphoma

1 reference

12 December 2020

JAK2 phosphorylates histone H3Y41 and excludes HP1alpha from chromatin

1 reference

12 December 2020

Multiple distinct sets of stereotyped antigen receptors indicate a role for antigen in promoting chronic lymphocytic leukemia

1 reference

12 December 2020

Chronic lymphocytic leukemia cells recognize conserved epitopes associated with apoptosis and oxidation

1 reference

12 December 2020

Defective B cell receptor-mediated responses in mice lacking the Ets protein, Spi-B.

1 reference

12 December 2020

A microRNA polycistron as a potential human oncogene

1 reference

12 December 2020

A Small-Molecule Inhibitor of BCL6 Kills DLBCL Cells In Vitro and In Vivo

1 reference

12 December 2020

Self-renewing hematopoietic stem cell is the primary target in pathogenesis of human chronic lymphocytic leukemia

1 reference

12 December 2020

Hypermutation of multiple proto-oncogenes in B-cell diffuse large-cell lymphomas

1 reference

12 December 2020

Blimp-1, a novel zinc finger-containing protein that can drive the maturation of B lymphocytes into immunoglobulin-secreting cells

1 reference

12 December 2020

Analysis of VH genes in follicular and diffuse lymphoma shows ongoing somatic mutation and multiple isotype transcripts in early disease with changes during disease progression.

1 reference

12 December 2020

BCL-6 regulates chemokine gene transcription in macrophages

1 reference

12 December 2020

Casein kinase 1alpha governs antigen-receptor-induced NF-kappaB activation and human lymphoma cell survival

1 reference

12 December 2020

MicroRNA-34a perturbs B lymphocyte development by repressing the forkhead box transcription factor Foxp1.

1 reference

12 December 2020

BCL-6, a POZ/zinc-finger protein, is a sequence-specific transcriptional repressor

1 reference

12 December 2020

IRF4 addiction in multiple myeloma

1 reference

12 December 2020

Update on Hsp90 inhibitors in clinical trial.

1 reference

12 December 2020

Control of developmental regulators by Polycomb in human embryonic stem cells

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12 December 2020

Involvement of the bcl-2 gene in human follicular lymphoma

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12 December 2020

JAK signaling globally counteracts heterochromatic gene silencing

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12 December 2020

Cancer proliferation gene discovery through functional genomics.

1 reference

12 December 2020

The TRAF6 ubiquitin ligase and TAK1 kinase mediate IKK activation by BCL10 and MALT1 in T lymphocytes

1 reference

12 December 2020

Bcl10 activates the NF-kappaB pathway through ubiquitination of NEMO

1 reference

12 December 2020

Mantle cell lymphoma: biology, pathogenesis, and the molecular basis of treatment in the genomic era

1 reference

12 December 2020

In vivo ablation of surface immunoglobulin on mature B cells by inducible gene targeting results in rapid cell death.

1 reference

12 December 2020

Survival of resting mature B lymphocytes depends on BCR signaling via the Igalpha/beta heterodimer

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12 December 2020

Bcl-2 gene promotes haemopoietic cell survival and cooperates with c-myc to immortalize pre-B cells

1 reference

12 December 2020

Integrative analysis reveals selective 9p24.1 amplification, increased PD-1 ligand expression, and further induction via JAK2 in nodular sclerosing Hodgkin lymphoma and primary mediastinal large B-cell lymphoma.

1 reference

12 December 2020

Recruitment of the cytoplasmic adaptor Grb2 to surface IgG and IgE provides antigen receptor-intrinsic costimulation to class-switched B cells

1 reference

12 December 2020

Mechanisms of B-cell lymphoma pathogenesis

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12 December 2020

Assembly requirements of PU.1-Pip (IRF-4) activator complexes: inhibiting function in vivo using fused dimers

1 reference

12 December 2020

TNFAIP3/A20 functions as a novel tumor suppressor gene in several subtypes of non-Hodgkin lymphomas

1 reference

12 December 2020

The B cell receptor governs the subcellular location of Toll-like receptor 9 leading to hyperresponses to DNA-containing antigens

1 reference

12 December 2020

Somatic hypermutation in low-grade mucosa-associated lymphoid tissue-type B-cell lymphoma

1 reference

12 December 2020

The isotype of the BCR as a surrogate for the GCB and ABC molecular subtypes in diffuse large B-cell lymphoma.

1 reference

12 December 2020

Burst-enhancing role of the IgG membrane tail as a molecular determinant of memory.

1 reference

12 December 2020

The human thymus contains a novel population of B lymphocytes

1 reference

12 December 2020

Regression of splenic lymphoma with villous lymphocytes after treatment of hepatitis C virus infection

1 reference

12 December 2020

Constitutive nuclear factor kappaB activity is required for survival of activated B cell-like diffuse large B cell lymphoma cells

1 reference

12 December 2020

The transcriptional coactivators p300 and CBP are histone acetyltransferases

1 reference

12 December 2020

Predominant autoantibody production by early human B cell precursors

1 reference

12 December 2020

Coordinated activities of wild-type plus mutant EZH2 drive tumor-associated hypertrimethylation of lysine 27 on histone H3 (H3K27) in human B-cell lymphomas

1 reference

12 December 2020

Heat shock factor 1 is a powerful multifaceted modifier of carcinogenesis

1 reference

12 December 2020

Mutations of the BCL6 proto-oncogene disrupt its negative autoregulation in diffuse large B-cell lymphoma.

1 reference

12 December 2020

Two antigen-independent adhesion pathways used by human cytotoxic T-cell clones

1 reference

12 December 2020

BRAF mutations in hairy-cell leukemia

1 reference

12 December 2020

An inhibitor of NEDD8-activating enzyme as a new approach to treat cancer

1 reference

12 December 2020

R406, an orally available spleen tyrosine kinase inhibitor blocks fc receptor signaling and reduces immune complex-mediated inflammation

1 reference

12 December 2020

Principles of cancer therapy: oncogene and non-oncogene addiction

1 reference

12 December 2020

MicroRNAs regulate critical genes associated with multiple myeloma pathogenesis

1 reference

12 December 2020

Acquisition of potential N-glycosylation sites in the immunoglobulin variable region by somatic mutation is a distinctive feature of follicular lymphoma.

1 reference

12 December 2020

MHC class II transactivator CIITA is a recurrent gene fusion partner in lymphoid cancers

1 reference

12 December 2020

HLA class II expression by Hodgkin Reed-Sternberg cells is an independent prognostic factor in classical Hodgkin's lymphoma.

1 reference

12 December 2020

Lymphoplasmacytic lymphoma/Waldenström macroglobulinemia: one disease or three?

1 reference

12 December 2020

Association of Ig/BCL6 translocations with germinal center B lymphocytes in human lymphoid tissues: implications for malignant transformation

1 reference

12 December 2020

Gastric MALT lymphoma B cells express polyreactive, somatically mutated immunoglobulins.

1 reference

12 December 2020

Identification of paracaspases and metacaspases: two ancient families of caspase-like proteins, one of which plays a key role in MALT lymphoma

1 reference

12 December 2020

The constant region of the membrane immunoglobulin mediates B cell-receptor clustering and signaling in response to membrane antigens.

1 reference

12 December 2020

Molecular subtypes of diffuse large B-cell lymphoma arise by distinct genetic pathways

1 reference

12 December 2020

V(H) mutation status, CD38 expression level, genomic aberrations, and survival in chronic lymphocytic leukemia.

1 reference

12 December 2020

Identification and characterization of a novel gene, C13orf25, as a target for 13q31-q32 amplification in malignant lymphoma

1 reference

12 December 2020

Targeting MYC dependence in cancer by inhibiting BET bromodomains

1 reference

12 December 2020

The molecular assembly and organization of signaling active B-cell receptor oligomers.

1 reference

12 December 2020

Developmental toxicity associated with receptor tyrosine kinase Ret inhibition in reproductive toxicity testing

1 reference

12 December 2020

Essential role of MALT1 protease activity in activated B cell-like diffuse large B-cell lymphoma.

1 reference

12 December 2020

The proliferation gene expression signature is a quantitative integrator of oncogenic events that predicts survival in mantle cell lymphoma

1 reference

12 December 2020

Hepatitis viruses and non-Hodgkin lymphoma: epidemiology, mechanisms of tumorigenesis, and therapeutic opportunities.

1 reference

12 December 2020

Transcriptional control of early B cell development

1 reference

12 December 2020

Analysis of the coding genome of diffuse large B-cell lymphoma

1 reference

12 December 2020

Rel-dependent induction of A1 transcription is required to protect B cells from antigen receptor ligation-induced apoptosis

1 reference

12 December 2020

CtBP is an essential corepressor for BCL6 autoregulation

1 reference

12 December 2020

BH3 profiling identifies three distinct classes of apoptotic blocks to predict response to ABT-737 and conventional chemotherapeutic agents

1 reference

12 December 2020

1 reference

12 December 2020

Frequent inactivation of A20 in B-cell lymphomas

1 reference

12 December 2020

Somatic mutations at EZH2 Y641 act dominantly through a mechanism of selectively altered PRC2 catalytic activity, to increase H3K27 trimethylation

1 reference

12 December 2020

Phosphorylation of the CARMA1 linker controls NF-kappaB activation

1 reference

12 December 2020

Control of oncogenesis and cancer therapy resistance by the transcription factor NF-kappaB.

1 reference

12 December 2020

Regression of primary low-grade B-cell gastric lymphoma of mucosa-associated lymphoid tissue type after eradication of Helicobacter pylori

1 reference

12 December 2020

1 reference

12 December 2020

Helical assembly in the MyD88–IRAK4–IRAK2 complex in TLR/IL-1R signalling

1 reference

12 December 2020

RNAi screen identifies Brd4 as a therapeutic target in acute myeloid leukaemia

1 reference

12 December 2020

Is NF-kappaB a good target for cancer therapy? Hopes and pitfalls

1 reference

12 December 2020

Synergistic activation of transcription by CBP and p53

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12 December 2020

Hodgkin's lymphoma cell lines are characterized by frequent aberrations on chromosomes 2p and 9p including REL and JAK2.

1 reference

12 December 2020

The putative oncogene GASC1 demethylates tri- and dimethylated lysine 9 on histone H3

1 reference

12 December 2020

Mutations of the tumor suppressor gene SOCS-1 in classical Hodgkin lymphoma are frequent and associated with nuclear phospho-STAT5 accumulation

1 reference

12 December 2020

Burkitt's lymphoma is a malignancy of mature B cells expressing somatically mutated V region genes

1 reference

12 December 2020

Identifying the MAGUK protein Carma-1 as a central regulator of humoral immune responses and atopy by genome-wide mouse mutagenesis.

1 reference

12 December 2020

Effects of Interleukin-13 Blockade on Allergen-induced Airway Responses in Mild Atopic Asthma

1 reference

12 December 2020

Lyn tyrosine kinase: accentuating the positive and the negative

1 reference

12 December 2020

Promoting apoptosis as a strategy for cancer drug discovery

1 reference

12 December 2020

Loss of MHC class II gene and protein expression in diffuse large B-cell lymphoma is related to decreased tumor immunosurveillance and poor patient survival regardless of other prognostic factors: a follow-up study from the Leukemia and Lymphoma Mol

1 reference

12 December 2020

BCL-6 negatively regulates expression of the NF-kappaB1 p105/p50 subunit

1 reference

12 December 2020

Constitutively activated STAT3 promotes cell proliferation and survival in the activated B-cell subtype of diffuse large B-cell lymphomas

1 reference

12 December 2020

A gene expression-based method to diagnose clinically distinct subgroups of diffuse large B cell lymphoma

1 reference

12 December 2020

Association of a microRNA/TP53 feedback circuitry with pathogenesis and outcome of B-cell chronic lymphocytic leukemia

1 reference

12 December 2020

Novel zinc finger gene implicated as myc collaborator by retrovirally accelerated lymphomagenesis in E mu-myc transgenic mice.

1 reference

12 December 2020

BCL-6 represses genes that function in lymphocyte differentiation, inflammation, and cell cycle control.

1 reference

12 December 2020

DLEU2, frequently deleted in malignancy, functions as a critical host gene of the cell cycle inhibitory microRNAs miR-15a and miR-16-1

1 reference

12 December 2020

Truncation in CCND1 mRNA alters miR-16-1 regulation in mantle cell lymphoma

1 reference

12 December 2020

Origin of chromosomal translocations in lymphoid cancer

1 reference

12 December 2020

The molecular signature of mediastinal large B-cell lymphoma differs from that of other diffuse large B-cell lymphomas and shares features with classical Hodgkin lymphoma.

1 reference

12 December 2020

Abnormal microRNA-16 locus with synteny to human 13q14 linked to CLL in NZB mice

1 reference

12 December 2020

Molecular diagnosis of Burkitt's lymphoma

1 reference

12 December 2020

c-Myc-regulated microRNAs modulate E2F1 expression

1 reference

12 December 2020

Oncogenically active MYD88 mutations in human lymphoma

1 reference

12 December 2020

BCL6-mediated attenuation of DNA damage sensing triggers growth arrest and senescence through a p53-dependent pathway in a cell context-dependent manner.

1 reference

12 December 2020

Pathogenesis of classical and lymphocyte-predominant Hodgkin lymphoma

1 reference

12 December 2020

Mutations of multiple genes cause deregulation of NF-kappaB in diffuse large B-cell lymphoma.

1 reference

12 December 2020

A20, ABIN-1/2, and CARD11 mutations and their prognostic value in gastrointestinal diffuse large B-cell lymphoma.

1 reference

12 December 2020

Acquired resistance to ABT-737 in lymphoma cells that up-regulate MCL-1 and BFL-1.

1 reference

12 December 2020

Inducibility of kappa immunoglobulin enhancer-binding protein Nf-kappa B by a posttranslational mechanism

1 reference

12 December 2020

TNFAIP3 (A20) is a tumor suppressor gene in Hodgkin lymphoma and primary mediastinal B cell lymphoma

1 reference

12 December 2020

EZH2 Y641 mutations in follicular lymphoma.

1 reference

12 December 2020

Blimp-1 is required for maintenance of long-lived plasma cells in the bone marrow

1 reference

12 December 2020

Loss of major histocompatibility class II gene and protein expression in primary mediastinal large B-cell lymphoma is highly coordinated and related to poor patient survival

1 reference

12 December 2020

MLN4924, a NEDD8-activating enzyme inhibitor, is active in diffuse large B-cell lymphoma models: rationale for treatment of NF-{kappa}B-dependent lymphoma

1 reference

12 December 2020

MicroRNA-17-92 down-regulates expression of distinct targets in different B-cell lymphoma subtypes

1 reference

12 December 2020

Nonredundant and complementary functions of TRAF2 and TRAF3 in a ubiquitination cascade that activates NIK-dependent alternative NF-kappaB signaling

1 reference

12 December 2020

Cooperative epigenetic modulation by cancer amplicon genes

1 reference

12 December 2020

DNA fiber fluorescence in situ hybridization analysis of immunoglobulin class switching in B-cell neoplasia: aberrant CH gene rearrangements in follicle center-cell lymphoma

1 reference

12 December 2020

Selective inhibition of BET bromodomains

1 reference

12 December 2020

CREBBP mutations in relapsed acute lymphoblastic leukaemia

1 reference

12 December 2020

Cooperative demethylation by JMJD2C and LSD1 promotes androgen receptor-dependent gene expression

1 reference

12 December 2020

Point mutations and genomic deletions in CCND1 create stable truncated cyclin D1 mRNAs that are associated with increased proliferation rate and shorter survival

1 reference

12 December 2020

B-cell lymphoma 6 and the molecular pathogenesis of diffuse large B-cell lymphoma.

1 reference

12 December 2020

Whole-genome sequencing identifies recurrent mutations in chronic lymphocytic leukaemia

1 reference

12 December 2020

Cooperative signaling through the signal transducer and activator of transcription 3 and nuclear factor-{kappa}B pathways in subtypes of diffuse large B-cell lymphoma

1 reference

12 December 2020

Janus kinase inhibitors for the treatment of myeloproliferative neoplasias and beyond

1 reference

12 December 2020

Low molecular weight inhibitors of Myc-Max interaction and function

1 reference

12 December 2020

Direct repression of prdm1 by Bcl-6 inhibits plasmacytic differentiation

1 reference

12 December 2020

BCL-6 mutations in normal germinal center B cells: evidence of somatic hypermutation acting outside Ig loci

1 reference

12 December 2020

Proteolytic cleavage in an endolysosomal compartment is required for activation of Toll-like receptor 9

1 reference

12 December 2020

Binding and modulation of p53 by p300/CBP coactivators

1 reference

12 December 2020

BCoR, a novel corepressor involved in BCL-6 repression

1 reference

12 December 2020

Among B cell non-Hodgkin's lymphomas, MALT lymphomas express a unique antibody repertoire with frequent rheumatoid factor reactivity

1 reference

12 December 2020

Profiling essential genes in human mammary cells by multiplex RNAi screening

1 reference

12 December 2020

Suppression of inflammation by a synthetic histone mimic

1 reference

12 December 2020

Sequential transcription factor targeting for diffuse large B-cell lymphomas

1 reference

12 December 2020

miR-19 is a key oncogenic component of mir-17-92

1 reference

12 December 2020

T cell antigen receptor stimulation induces MALT1 paracaspase-mediated cleavage of the NF-kappaB inhibitor A20

1 reference

12 December 2020

Chronic active B-cell-receptor signalling in diffuse large B-cell lymphoma

1 reference

12 December 2020

MicroRNA expression profiles classify human cancers

1 reference

12 December 2020

Interleukin 13 is secreted by and stimulates the growth of Hodgkin and Reed-Sternberg cells

1 reference

12 December 2020

The DLEU2/miR-15a/16-1 cluster controls B cell proliferation and its deletion leads to chronic lymphocytic leukemia

1 reference

12 December 2020

Type I interferon receptor controls B-cell expression of nucleic acid-sensing Toll-like receptors and autoantibody production in a murine model of lupus.

1 reference

12 December 2020

Identification of a novel gene, GASC1, within an amplicon at 9p23-24 frequently detected in esophageal cancer cell lines

1 reference

12 December 2020

Ongoing immunoglobulin somatic mutation in germinal center B cell-like but not in activated B cell-like diffuse large cell lymphomas

1 reference

12 December 2020

Inactivating mutations of acetyltransferase genes in B-cell lymphoma

1 reference

12 December 2020

Inactivating SOCS1 mutations are caused by aberrant somatic hypermutation and restricted to a subset of B-cell lymphoma entities.

1 reference

12 December 2020

Antigen receptor tail clue.

1 reference

12 December 2020

Initial genome sequencing and analysis of multiple myeloma

1 reference

12 December 2020

Glycosylation of surface Ig creates a functional bridge between human follicular lymphoma and microenvironmental lectins

1 reference

12 December 2020

Recruitment of p300/CBP in p53-dependent signal pathways

1 reference

12 December 2020

Transgenic models of lymphoid neoplasia and development of a pan-hematopoietic vector

1 reference

12 December 2020

Mucosa-associated lymphoid tissue lymphoma: novel translocations including rearrangements of ODZ2, JMJD2C, and CNN3.

1 reference

12 December 2020

Constitutive canonical NF-κB activation cooperates with disruption of BLIMP1 in the pathogenesis of activated B cell-like diffuse large cell lymphoma

1 reference

12 December 2020

Is there a role for antigen selection in mantle cell lymphoma? Immunogenetic support from a series of 807 cases

1 reference

12 December 2020

Syk protein-tyrosine kinase is regulated by tyrosine-phosphorylated Ig alpha/Ig beta immunoreceptor tyrosine activation motif binding and autophosphorylation

1 reference

12 December 2020

Ig gene diversification and selection in follicular lymphoma, diffuse large B cell lymphoma and primary central nervous system lymphoma revealed by lineage tree and mutation analyses.

1 reference

12 December 2020

Frequent deletions and down-regulation of micro- RNA genes miR15 and miR16 at 13q14 in chronic lymphocytic leukemia

1 reference

12 December 2020

Systematic review: regression of lymphoproliferative disorders after treatment for hepatitis C infection.

1 reference

12 December 2020

Lineage dependency and lineage-survival oncogenes in human cancer

1 reference

12 December 2020

A loss-of-function RNA interference screen for molecular targets in cancer

1 reference

12 December 2020

Negative autoregulation of BCL-6 is bypassed by genetic alterations in diffuse large B cell lymphomas

1 reference

12 December 2020

Tyrosine kinases and their substrates in B lymphocytes

1 reference

12 December 2020

Inactivation of the PRDM1/BLIMP1 gene in diffuse large B cell lymphoma

1 reference

12 December 2020

BCL6 suppression of BCL2 via Miz1 and its disruption in diffuse large B cell lymphoma

1 reference

12 December 2020

Mechanisms of apoptosis sensitivity and resistance to the BH3 mimetic ABT-737 in acute myeloid leukemia

1 reference

12 December 2020

Chromatin-IgG complexes activate B cells by dual engagement of IgM and Toll-like receptors

1 reference

12 December 2020

Resistance to CpG DNA-induced autoimmunity through tolerogenic B cell antigen receptor ERK signaling

1 reference

12 December 2020

Programmed anuclear cell death delimits platelet life span.

1 reference

12 December 2020

From pathogenesis to treatment of chronic lymphocytic leukaemia

1 reference

12 December 2020

Lessons from the bare lymphocyte syndrome: molecular mechanisms regulating MHC class II expression.

1 reference

12 December 2020

Jmjd1a and Jmjd2c histone H3 Lys 9 demethylases regulate self-renewal in embryonic stem cells

1 reference

12 December 2020

Blimp-1 orchestrates plasma cell differentiation by extinguishing the mature B cell gene expression program

1 reference

12 December 2020

How chromatin-binding modules interpret histone modifications: lessons from professional pocket pickers

1 reference

12 December 2020

Helicobacter pylori-specific tumour-infiltrating T cells provide contact dependent help for the growth of malignant B cells in low-grade gastric lymphoma of mucosa-associated lymphoid tissue

1 reference

12 December 2020

The concept of synthetic lethality in the context of anticancer therapy

1 reference

12 December 2020

A distinct signaling pathway used by the IgG-containing B cell antigen receptor

1 reference

12 December 2020

Oncogenic CARD11 Mutations Induce Hyperactive Signaling by Disrupting Autoinhibition by the PKC-Responsive Inhibitory Domain

1 reference

12 December 2020

Nucleic acid recognition by Toll-like receptors is coupled to stepwise processing by cathepsins and asparagine endopeptidase.

1 reference

12 December 2020

Regulation of autoreactive antibodies

1 reference

12 December 2020

The 2008 WHO classification of lymphoid neoplasms and beyond: evolving concepts and practical applications

1 reference

12 December 2020

BCL6 interacts with the transcription factor Miz-1 to suppress the cyclin-dependent kinase inhibitor p21 and cell cycle arrest in germinal center B cells

1 reference

12 December 2020

Control of inflammation, cytokine expression, and germinal center formation by BCL-6

1 reference

12 December 2020

Primary mediastinal (thymic) B-cell lymphoma is characterized by gains of chromosomal material including 9p and amplification of the REL gene

1 reference

12 December 2020

IRF4: Immunity. Malignancy! Therapy?

1 reference

12 December 2020

The biology of hairy-cell leukaemia

1 reference

12 December 2020

The genetic landscape of the childhood cancer medulloblastoma

1 reference

12 December 2020

Comprehensive genomic analysis of desmoplastic medulloblastomas: identification of novel amplified genes and separate evaluation of the different histological components

1 reference

12 December 2020

Genetic and molecular pathogenesis of mantle cell lymphoma: perspectives for new targeted therapeutics

1 reference

12 December 2020

Pip, a lymphoid-restricted IRF, contains a regulatory domain that is important for autoinhibition and ternary complex formation with the Ets factor PU.1.

1 reference

12 December 2020

A peptomimetic inhibitor of BCL6 with potent antilymphoma effects in vitro and in vivo

1 reference

12 December 2020

Anergic responses characterize a large fraction of human autoreactive naive B cells expressing low levels of surface IgM.

1 reference

12 December 2020

Widespread shortening of 3'UTRs by alternative cleavage and polyadenylation activates oncogenes in cancer cells

1 reference

12 December 2020

Graded expression of interferon regulatory factor-4 coordinates isotype switching with plasma cell differentiation

1 reference

12 December 2020

Oncogenic CARD11 mutations in human diffuse large B cell lymphoma

1 reference

12 December 2020

BCL6: master regulator of the germinal center reaction and key oncogene in B cell lymphomagenesis

1 reference

12 December 2020

Relation of gene expression phenotype to immunoglobulin mutation genotype in B cell chronic lymphocytic leukemia

1 reference

12 December 2020

Stage-specific modulation of IFN-regulatory factor 4 function by Krüppel-type zinc finger proteins

1 reference

12 December 2020

PTEN gene alterations in lymphoid neoplasms

1 reference

12 December 2020

Identification of cooperating oncogenes in E mu-myc transgenic mice by provirus tagging

1 reference

12 December 2020

Effects of IL-1 receptor-associated kinase (IRAK) expression on IL-1 signaling are independent of its kinase activity

1 reference

12 December 2020

Tracking CD40 signaling during germinal center development

1 reference

12 December 2020

Characterization of the B lymphocyte populations in Lyn-deficient mice and the role of Lyn in signal initiation and down-regulation

1 reference

12 December 2020

Nucleotide sequence of a t(14;18) chromosomal breakpoint in follicular lymphoma and demonstration of a breakpoint-cluster region near a transcriptionally active locus on chromosome 18.

1 reference

12 December 2020

Clonal evolution of a follicular lymphoma: evidence for antigen selection

1 reference

12 December 2020

Pyogenic bacterial infections in humans with IRAK-4 deficiency

1 reference

12 December 2020

Genetic dissection of the miR-17~92 cluster of microRNAs in Myc-induced B-cell lymphomas

1 reference

12 December 2020

Distinctive patterns of BCL6 molecular alterations and their functional consequences in different subgroups of diffuse large B-cell lymphoma

1 reference

12 December 2020

Translocations activating IRF4 identify a subtype of germinal center-derived B-cell lymphoma affecting predominantly children and young adults

1 reference

12 December 2020

Chronic lymphocytic leukemia B cells express restricted sets of mutated and unmutated antigen receptors.

1 reference

12 December 2020

A signaling pathway mediating downregulation of BCL6 in germinal center B cells is blocked by BCL6 gene alterations in B cell lymphoma.

1 reference

12 December 2020

MALT lymphoma: from morphology to molecules

1 reference

12 December 2020

Ig beta tyrosine residues contribute to the control of B cell receptor signaling by regulating receptor internalization

1 reference

12 December 2020

Transcriptional repression by the proto-oncogene BCL-6.

1 reference

12 December 2020

Unique signaling properties of B cell antigen receptor in mature and immature B cells: implications for tolerance and activation

1 reference

12 December 2020

Blimp-1 Is Required for the Formation of Immunoglobulin Secreting Plasma Cells and Pre-Plasma Memory B Cells

1 reference

12 December 2020

Mouse models of non-Hodgkin lymphoma reveal Syk as an important therapeutic target

1 reference

12 December 2020

Receptor editing is the main mechanism of B cell tolerance toward membrane antigens

1 reference

12 December 2020

Ongoing mutation in MALT lymphoma immunoglobulin gene suggests that antigen stimulation plays a role in the clonal expansion.

1 reference

12 December 2020

Maintenance of B cell anergy requires constant antigen receptor occupancy and signaling

1 reference

12 December 2020

Details of Toll-like receptor:adapter interaction revealed by germ-line mutagenesis

1 reference

12 December 2020

Frequent engagement of the classical and alternative NF-kappaB pathways by diverse genetic abnormalities in multiple myeloma

1 reference

12 December 2020

Somatic mutations altering EZH2 (Tyr641) in follicular and diffuse large B-cell lymphomas of germinal-center origin

1 reference

12 December 2020

Structural profiles of TP53 gene mutations predict clinical outcome in diffuse large B-cell lymphoma: an international collaborative study.

1 reference

12 December 2020

Homeostatic MyD88-dependent signals cause lethal inflamMation in the absence of A20.

1 reference

12 December 2020

Bruton's tyrosine kinase links the B cell receptor to nuclear factor kappaB activation

1 reference

12 December 2020

Critical role of PI3K signaling for NF-kappaB-dependent survival in a subset of activated B-cell-like diffuse large B-cell lymphoma cells.

1 reference

12 December 2020

Bortezomib resistance in mantle cell lymphoma is associated with plasmacytic differentiation

1 reference

12 December 2020

Covalent histone modifications--miswritten, misinterpreted and mis-erased in human cancers

1 reference

12 December 2020

The role of mechanistic factors in promoting chromosomal translocations found in lymphoid and other cancers

1 reference

12 December 2020

Non-oncogene addiction and the stress phenotype of cancer cells

1 reference

12 December 2020

Charting histone modifications and the functional organization of mammalian genomes

1 reference

12 December 2020

Lineage-specific modulation of interleukin 4 signaling by interferon regulatory factor 4

1 reference

12 December 2020

Molecular cytogenetic characterization of a metastatic lung sarcomatoid carcinoma: 9p23 neocentromere and 9p23-p24 amplification including JAK2 and JMJD2C

1 reference

12 December 2020

Biallelic mutation of SOCS-1 impairs JAK2 degradation and sustains phospho-JAK2 action in the MedB-1 mediastinal lymphoma line

1 reference

12 December 2020

BCL2 translocation defines a unique tumor subset within the germinal center B-cell-like diffuse large B-cell lymphoma

1 reference

12 December 2020

A library of gene expression signatures to illuminate normal and pathological lymphoid biology

1 reference

12 December 2020

Many chronic lymphocytic leukemia antibodies recognize apoptotic cells with exposed nonmuscle myosin heavy chain IIA: implications for patient outcome and cell of origin

1 reference

12 December 2020

A negative regulatory role for Ig-alpha during B cell development

1 reference

12 December 2020

A recurrent nonrandom translocation (3;7)(q27;p12) associated with BCL-6 gene rearrangement in B-cell diffuse large cell lymphoma

1 reference

12 December 2020

The interleukin-1 receptor-associated kinase is degraded by proteasomes following its phosphorylation

1 reference

12 December 2020

Endocytic sequestration of the B cell antigen receptor and toll-like receptor 9 in anergic cells

1 reference

12 December 2020

Analysis of VH genes used by neoplastic B cells in endemic Burkitt's lymphoma shows somatic hypermutation and intraclonal heterogeneity

1 reference

12 December 2020

MALT lymphoma: many roads lead to nuclear factor-κb activation

1 reference

12 December 2020

The biology of Hodgkin's lymphoma

1 reference

12 December 2020

CD19 is essential for B cell activation by promoting B cell receptor–antigen microcluster formation in response to membrane-bound ligand

1 reference

12 December 2020

Molecular diagnosis of primary mediastinal B cell lymphoma identifies a clinically favorable subgroup of diffuse large B cell lymphoma related to Hodgkin lymphoma

1 reference

12 December 2020

Bortezomib plus CHOP-rituximab for previously untreated diffuse large B-cell lymphoma and mantle cell lymphoma

1 reference

12 December 2020

Genetic rearrangement of FOXP1 is predominantly detected in a subset of diffuse large B-cell lymphomas with extranodal presentation.

1 reference

12 December 2020

Mutational analysis of PRDM1 indicates a tumor-suppressor role in diffuse large B-cell lymphomas

1 reference

12 December 2020

In vivo intraclonal and interclonal kinetic heterogeneity in B-cell chronic lymphocytic leukemia

1 reference

12 December 2020

PU.1 and Spi-B are required for normal B cell receptor-mediated signal transduction

1 reference

12 December 2020

Intrinsic properties of immunoglobulin IgG1 isotype-switched B cell receptors promote microclustering and the initiation of signaling

1 reference

12 December 2020

Repression of the miR-17-92 cluster by p53 has an important function in hypoxia-induced apoptosis

1 reference

12 December 2020

Compensatory IKKalpha activation of classical NF-kappaB signaling during IKKbeta inhibition identified by an RNA interference sensitization screen

1 reference

12 December 2020

Selective predisposition to bacterial infections in IRAK-4-deficient children: IRAK-4-dependent TLRs are otherwise redundant in protective immunity

1 reference

12 December 2020

Oncogenic activation of NF-kappaB.

1 reference

12 December 2020

EZH2-mediated epigenetic silencing in germinal center B cells contributes to proliferation and lymphomagenesis

1 reference

12 December 2020

Acetylation of p65 at lysine 314 is important for late NF-kappaB-dependent gene expression

1 reference

12 December 2020

The BCL-6 proto-oncogene controls germinal-centre formation and Th2-type inflammation

1 reference

12 December 2020

Proliferating cells express mRNAs with shortened 3' untranslated regions and fewer microRNA target sites

1 reference

12 December 2020

Inhibition of Syk with fostamatinib disodium has significant clinical activity in non-Hodgkin lymphoma and chronic lymphocytic leukemia

1 reference

12 December 2020

Unmutated Ig V(H) genes are associated with a more aggressive form of chronic lymphocytic leukemia.

1 reference

12 December 2020

Homozygous deletion of SOCS1 in primary mediastinal B-cell lymphoma detected by CGH to BAC microarrays

1 reference

12 December 2020

Multiple layers of B cell memory with different effector functions

1 reference

12 December 2020

NFkappaB activity, function, and target-gene signatures in primary mediastinal large B-cell lymphoma and diffuse large B-cell lymphoma subtypes

1 reference

12 December 2020

Cloning the chromosomal breakpoint of t(14;18) human lymphomas: clustering around JH on chromosome 14 and near a transcriptional unit on 18.

1 reference

12 December 2020

Receptors, subcellular compartments and the regulation of peripheral B cell responses: the illuminating state of anergy

1 reference

12 December 2020

10.1146/ANNUREV-IMMUNOL-020711-075027

Identifiers

DOI

1 reference

31 July 2017

0 references

1 reference