Home
Random
Nearby
Log in
Settings
Donate
About Wikidata
Disclaimers
Search
(Q35036374)
Watch
English
Nutrient-sensing mechanisms and pathways.
scientific article
In more languages
edit
Statements
instance of
scholarly article
1 reference
stated in
Europe PubMed Central
PMC publication ID
4313349
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25592535%20AND%20SRC:MED&resulttype=core&format=json
retrieved
28 February 2020
review article
1 reference
stated in
Europe PubMed Central
title
Nutrient-sensing mechanisms and pathways
(English)
1 reference
stated in
Europe PubMed Central
PMC publication ID
4313349
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25592535%20AND%20SRC:MED&resulttype=core&format=json
retrieved
28 February 2020
author
Alejo Efeyan
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMC publication ID
4313349
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25592535%20AND%20SRC:MED&resulttype=core&format=json
retrieved
28 February 2020
David M. Sabatini
series ordinal
3
1 reference
stated in
Europe PubMed Central
PMC publication ID
4313349
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25592535%20AND%20SRC:MED&resulttype=core&format=json
retrieved
28 February 2020
author name string
William C Comb
series ordinal
2
1 reference
stated in
Europe PubMed Central
PMC publication ID
4313349
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25592535%20AND%20SRC:MED&resulttype=core&format=json
retrieved
28 February 2020
language of work or name
English
0 references
publication date
1 January 2015
1 reference
stated in
Europe PubMed Central
PMC publication ID
4313349
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25592535%20AND%20SRC:MED&resulttype=core&format=json
retrieved
28 February 2020
published in
Nature
1 reference
stated in
Europe PubMed Central
PMC publication ID
4313349
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25592535%20AND%20SRC:MED&resulttype=core&format=json
retrieved
28 February 2020
volume
517
1 reference
stated in
Europe PubMed Central
PMC publication ID
4313349
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25592535%20AND%20SRC:MED&resulttype=core&format=json
retrieved
28 February 2020
issue
7534
1 reference
stated in
Europe PubMed Central
PMC publication ID
4313349
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25592535%20AND%20SRC:MED&resulttype=core&format=json
retrieved
28 February 2020
page(s)
302-310
1 reference
stated in
Europe PubMed Central
PMC publication ID
4313349
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25592535%20AND%20SRC:MED&resulttype=core&format=json
retrieved
28 February 2020
exact match
https://scigraph.springernature.com/pub.10.1038/nature14190
0 references
cites work
The Sestrins interact with GATOR2 to negatively regulate the amino-acid-sensing pathway upstream of mTORC1
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313349
retrieved
8 July 2018
Sestrins function as guanine nucleotide dissociation inhibitors for Rag GTPases to control mTORC1 signaling
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313349
retrieved
8 July 2018
Brain glucose sensing, glucokinase and neural control of metabolism and islet function
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313349
retrieved
8 July 2018
A Gpr120-selective agonist improves insulin resistance and chronic inflammation in obese mice
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313349
retrieved
8 July 2018
The search for antiaging interventions: from elixirs to fasting regimens
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313349
retrieved
8 July 2018
Autophagy is required for glucose homeostasis and lung tumor maintenance
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313349
retrieved
8 July 2018
Structure-function of CD36 and importance of fatty acid signal transduction in fat metabolism
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313349
retrieved
8 July 2018
The folliculin tumor suppressor is a GAP for the RagC/D GTPases that signal amino acid levels to mTORC1.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313349
retrieved
8 July 2018
Recruitment of folliculin to lysosomes supports the amino acid-dependent activation of Rag GTPases
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313349
retrieved
8 July 2018
Differential contribution of insulin and amino acids to the mTORC1-autophagy pathway in the liver and muscle
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313349
retrieved
8 July 2018
A Tumor suppressor complex with GAP activity for the Rag GTPases that signal amino acid sufficiency to mTORC1
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313349
retrieved
8 July 2018
Amino acid deprivation inhibits TORC1 through a GTPase-activating protein complex for the Rag family GTPase Gtr1.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313349
retrieved
8 July 2018
Point mutation in luminal loop 7 of Scap protein blocks interaction with loop 1 and abolishes movement to Golgi
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313349
retrieved
8 July 2018
Regulation of mTORC1 by the Rag GTPases is necessary for neonatal autophagy and survival.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313349
retrieved
8 July 2018
Ragulator is a GEF for the rag GTPases that signal amino acid levels to mTORC1
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313349
retrieved
8 July 2018
The G protein-coupled taste receptor T1R1/T1R3 regulates mTORC1 and autophagy.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313349
retrieved
8 July 2018
Amino acids and mTORC1: from lysosomes to disease
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313349
retrieved
8 July 2018
De novo somatic mutations in components of the PI3K-AKT3-mTOR pathway cause hemimegalencephaly
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313349
retrieved
8 July 2018
Regulation of glucose transport by insulin: traffic control of GLUT4.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313349
retrieved
8 July 2018
A unifying model for mTORC1-mediated regulation of mRNA translation.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313349
retrieved
8 July 2018
mTOR signaling in growth control and disease
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313349
retrieved
8 July 2018
Adiponectin: regulation of its production and its role in human diseases
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313349
retrieved
8 July 2018
AMPK: a nutrient and energy sensor that maintains energy homeostasis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313349
retrieved
8 July 2018
Dysfunction of lipid sensor GPR120 leads to obesity in both mouse and human
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313349
retrieved
8 July 2018
FOSL2 promotes leptin gene expression in human and mouse adipocytes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313349
retrieved
8 July 2018
The fatty acid translocase gene CD36 and lingual lipase influence oral sensitivity to fat in obese subjects
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313349
retrieved
8 July 2018
SREBPs: metabolic integrators in physiology and metabolism
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313349
retrieved
8 July 2018
Autophagy: renovation of cells and tissues
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313349
retrieved
8 July 2018
mTORC1 senses lysosomal amino acids through an inside-out mechanism that requires the vacuolar H(+)-ATPase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313349
retrieved
8 July 2018
AMP-activated protein kinase: an energy sensor that regulates all aspects of cell function
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313349
retrieved
8 July 2018
The lipid-sensor candidates CD36 and GPR120 are differentially regulated by dietary lipids in mouse taste buds: impact on spontaneous fat preference
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313349
retrieved
8 July 2018
Identification of luminal Loop 1 of Scap protein as the sterol sensor that maintains cholesterol homeostasis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313349
retrieved
8 July 2018
AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313349
retrieved
8 July 2018
Phosphorylation of ULK1 (hATG1) by AMP-activated protein kinase connects energy sensing to mitophagy
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313349
retrieved
8 July 2018
Autophagy and the integrated stress response
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313349
retrieved
8 July 2018
GPR120 is an omega-3 fatty acid receptor mediating potent anti-inflammatory and insulin-sensitizing effects
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313349
retrieved
8 July 2018
The cell biology of taste
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313349
retrieved
8 July 2018
Taste Preference for Fatty Acids Is Mediated by GPR40 and GPR120
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313349
retrieved
8 July 2018
Termination of autophagy and reformation of lysosomes regulated by mTOR
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313349
retrieved
8 July 2018
Ragulator-Rag complex targets mTORC1 to the lysosomal surface and is necessary for its activation by amino acids
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313349
retrieved
8 July 2018
Glucose transporters in the 21st Century
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313349
retrieved
8 July 2018
The Vam6 GEF controls TORC1 by activating the EGO complex
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313349
retrieved
8 July 2018
Regulation mechanisms and signaling pathways of autophagy
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313349
retrieved
8 July 2018
Diet soda intake and risk of incident metabolic syndrome and type 2 diabetes in the Multi-Ethnic Study of Atherosclerosis (MESA).
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313349
retrieved
8 July 2018
An ATP-competitive mammalian target of rapamycin inhibitor reveals rapamycin-resistant functions of mTORC1
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313349
retrieved
8 July 2018
Molecular mechanism for the umami taste synergism
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313349
retrieved
8 July 2018
Switch-like control of SREBP-2 transport triggered by small changes in ER cholesterol: a delicate balance
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313349
retrieved
8 July 2018
Beta-cell failure as a complication of diabetes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313349
retrieved
8 July 2018
Cellular program controlling the recovery of adipose tissue mass: An in vivo imaging approach.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313349
retrieved
8 July 2018
Regulation of TORC1 by Rag GTPases in nutrient response
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313349
retrieved
8 July 2018
The Rag GTPases bind raptor and mediate amino acid signaling to mTORC1
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313349
retrieved
8 July 2018
FoxO3 controls autophagy in skeletal muscle in vivo
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313349
retrieved
8 July 2018
Endocrine functions of adipose tissue
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313349
retrieved
8 July 2018
Sweet taste receptors in rat small intestine stimulate glucose absorption through apical GLUT2
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313349
retrieved
8 July 2018
Taste receptor genes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313349
retrieved
8 July 2018
Adiponectin and adiponectin receptors in insulin resistance, diabetes, and the metabolic syndrome
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313349
retrieved
8 July 2018
Loss of autophagy in the central nervous system causes neurodegeneration in mice
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313349
retrieved
8 July 2018
CD36 involvement in orosensory detection of dietary lipids, spontaneous fat preference, and digestive secretions
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313349
retrieved
8 July 2018
Gp78, a membrane-anchored ubiquitin ligase, associates with Insig-1 and couples sterol-regulated ubiquitination to degradation of HMG CoA reductase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313349
retrieved
8 July 2018
The GCN2 kinase biases feeding behavior to maintain amino acid homeostasis in omnivores
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313349
retrieved
8 July 2018
Impairment of starvation-induced and constitutive autophagy in Atg7-deficient mice
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313349
retrieved
8 July 2018
Intramembrane aspartic acid in SCAP protein governs cholesterol-induced conformational change
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313349
retrieved
8 July 2018
Expression of sweet taste receptors of the T1R family in the intestinal tract and enteroendocrine cells.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313349
retrieved
8 July 2018
Free fatty acids regulate gut incretin glucagon-like peptide-1 secretion through GPR120
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313349
retrieved
8 July 2018
The role of autophagy during the early neonatal starvation period
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313349
retrieved
8 July 2018
Glucokinase (GCK) mutations in hyper- and hypoglycemia: Maturity-onset diabetes of the young, permanent neonatal diabetes, and hyperinsulinemia of infancy
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313349
retrieved
8 July 2018
Tuberous sclerosis complex gene products, Tuberin and Hamartin, control mTOR signaling by acting as a GTPase-activating protein complex toward Rheb
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313349
retrieved
8 July 2018
Rheb GTPase is a direct target of TSC2 GAP activity and regulates mTOR signaling
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313349
retrieved
8 July 2018
Insulin activation of Rheb, a mediator of mTOR/S6K/4E-BP signaling, is inhibited by TSC1 and 2
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313349
retrieved
8 July 2018
Rheb is a direct target of the tuberous sclerosis tumour suppressor proteins
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313349
retrieved
8 July 2018
Free fatty acids regulate insulin secretion from pancreatic beta cells through GPR40.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313349
retrieved
8 July 2018
Accelerated degradation of HMG CoA reductase mediated by binding of insig-1 to its sterol-sensing domain
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313349
retrieved
8 July 2018
The GCN2 eIF2alpha kinase is required for adaptation to amino acid deprivation in mice
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313349
retrieved
8 July 2018
Crucial step in cholesterol homeostasis: sterols promote binding of SCAP to INSIG-1, a membrane protein that facilitates retention of SREBPs in ER
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313349
retrieved
8 July 2018
Cholesterol addition to ER membranes alters conformation of SCAP, the SREBP escort protein that regulates cholesterol metabolism
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313349
retrieved
8 July 2018
Diet-induced insulin resistance in mice lacking adiponectin/ACRP30
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313349
retrieved
8 July 2018
Morphology and dynamics of the endocytic pathway in Dictyostelium discoideum
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313349
retrieved
8 July 2018
An amino-acid taste receptor
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313349
retrieved
8 July 2018
Expression of bitter taste receptors of the T2R family in the gastrointestinal tract and enteroendocrine STC-1 cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313349
retrieved
8 July 2018
Mammalian sweet taste receptors
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313349
retrieved
8 July 2018
Translational control is required for the unfolded protein response and in vivo glucose homeostasis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313349
retrieved
8 July 2018
Autophagy as a regulated pathway of cellular degradation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313349
retrieved
8 July 2018
Uncharged tRNA activates GCN2 by displacing the protein kinase moiety from a bipartite tRNA-binding domain
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313349
retrieved
8 July 2018
Aminoacyl-tRNA synthesis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313349
retrieved
8 July 2018
Dispensable and indispensable amino acids for humans
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313349
retrieved
8 July 2018
Characterization of a mammalian homolog of the GCN2 eukaryotic initiation factor 2alpha kinase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313349
retrieved
8 July 2018
Regulation of glucose production by the liver
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313349
retrieved
8 July 2018
Dual roles for glucokinase in glucose homeostasis as determined by liver and pancreatic beta cell-specific gene knock-outs using Cre recombinase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313349
retrieved
8 July 2018
Arginine metabolism: nitric oxide and beyond
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313349
retrieved
8 July 2018
Amino acid sufficiency and mTOR regulate p70 S6 kinase and eIF-4E BP1 through a common effector mechanism
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313349
retrieved
8 July 2018
A mutation in the human leptin receptor gene causes obesity and pituitary dysfunction
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313349
retrieved
8 July 2018
Mutations in GLUT2, the gene for the liver-type glucose transporter, in patients with Fanconi-Bickel syndrome
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313349
retrieved
8 July 2018
AdipoQ is a novel adipose-specific gene dysregulated in obesity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313349
retrieved
8 July 2018
Abnormal splicing of the leptin receptor in diabetic mice
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313349
retrieved
8 July 2018
Mammalian glucokinase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313349
retrieved
8 July 2018
Positional cloning of the mouse obese gene and its human homologue
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313349
retrieved
8 July 2018
Unbound free fatty acid levels in human serum.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313349
retrieved
8 July 2018
Human and rat beta cells differ in glucose transporter but not in glucokinase gene expression
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313349
retrieved
8 July 2018
A Novel Serum Protein Similar to C1q, Produced Exclusively in Adipocytes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313349
retrieved
8 July 2018
A receptor-mediated pathway for cholesterol homeostasis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313349
retrieved
8 July 2018
Dynamic aspects of vacuolar and cytosolic amino acid pools of Saccharomyces cerevisiae
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313349
retrieved
8 July 2018
Autophagy is essential for preimplantation development of mouse embryos.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313349
retrieved
25 October 2018
The GCN2 eIF2alpha kinase regulates fatty-acid homeostasis in the liver during deprivation of an essential amino acid.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313349
retrieved
25 October 2018
A novel human primary immunodeficiency syndrome caused by deficiency of the endosomal adaptor protein p14.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313349
retrieved
25 October 2018
Uncharged tRNA and sensing of amino acid deficiency in mammalian piriform cortex.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313349
retrieved
25 October 2018
Direct binding of cholesterol to the purified membrane region of SCAP: mechanism for a sterol-sensing domain
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313349
retrieved
25 October 2018
Detection of sweet and umami taste in the absence of taste receptor T1r3.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313349
retrieved
25 October 2018
Association of adiponectin mutation with type 2 diabetes: a candidate gene for the insulin resistance syndrome
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313349
retrieved
25 October 2018
Genetic variation in the gene encoding adiponectin is associated with an increased risk of type 2 diabetes in the Japanese population.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313349
retrieved
25 October 2018
Genomic structure and mutations in adipose-specific gene, adiponectin
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4313349
retrieved
25 October 2018
Autophagy regulates lipid metabolism
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/25592535
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Lysosomal pool of free-amino acids
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/25592535
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1038/NATURE14190
1 reference
stated in
Europe PubMed Central
PMC publication ID
4313349
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25592535%20AND%20SRC:MED&resulttype=core&format=json
retrieved
28 February 2020
PMC publication ID
4313349
1 reference
stated in
Europe PubMed Central
PMC publication ID
4313349
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25592535%20AND%20SRC:MED&resulttype=core&format=json
retrieved
28 February 2020
PubMed publication ID
25592535
1 reference
stated in
Europe PubMed Central
PMC publication ID
4313349
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25592535%20AND%20SRC:MED&resulttype=core&format=json
retrieved
28 February 2020
ResearchGate publication ID
270963166
0 references
Sitelinks
Wikipedia
(0 entries)
edit
Wikibooks
(0 entries)
edit
Wikinews
(0 entries)
edit
Wikiquote
(0 entries)
edit
Wikisource
(0 entries)
edit
Wikiversity
(0 entries)
edit
Wikivoyage
(0 entries)
edit
Wiktionary
(0 entries)
edit
Multilingual sites
(0 entries)
edit