(Q37680983)

21 August 2017

1 reference

title

Expression of multiple granzymes by cytotoxic T lymphocyte implies that they activate diverse apoptotic pathways in target cells (English)

1 reference

21 August 2017

0 references

0 references

Fang Zhou

1

1 reference

21 August 2017

publication date

1 January 2010

1 reference

International Reviews of Immunology

21 August 2017

published in

1 reference

21 August 2017

volume

29

1 reference

21 August 2017

issue

1

1 reference

21 August 2017

page(s)

38-55

1 reference

Regulated cell death pathways: new twists in modulation of BCL2 family function

21 August 2017

cites work

1 reference

https://api.crossref.org/works/10.3109%2F08830180903247889

Regulation of apoptosis by the redox state of cytochrome c.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830180903247889

Calcium/calmodulin signaling elicits release of cytochrome c during 2,3,7,8-tetrachlorodibenzo-p-dioxin-induced apoptosis in the human lymphoblastic T-cell line, L-MAT.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830180903247889

Bcl-2 family proteins as regulators of oxidative stress

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830180903247889

Perforin triggers a plasma membrane-repair response that facilitates CTL induction of apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830180903247889

Characterization of the Fas ligand/Fas-dependent apoptosis of antiretroviral, class I MHC tetramer-defined, CD8+ CTL by in vivo retrovirus-infected cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830180903247889

Cytoprotection of human umbilical vein endothelial cells against apoptosis and CTL-mediated lysis provided by caspase-resistant Bcl-2 without alterations in growth or activation responses

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830180903247889

Presentation of a horse cytochrome c peptide by multiple H-2b class I major histocompatibility complex (MHC) molecules to C57BL/6- and bm1-derived cytotoxic T lymphocytes: presence of a single MHC anchor residue may confer efficient peptide-specific

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830180903247889

Apoptosis of human endometrium mediated by perforin and granzyme B of NK cells and cytotoxic T lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830180903247889

Granzymes: a family of lymphocyte granule serine proteases

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830180903247889

Granzymes (lymphocyte serine proteases): characterization with natural and synthetic substrates and inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830180903247889

High expression of alternative transcript of granzyme M in the mouse retina

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830180903247889

The restricted expression of granzyme M in human lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830180903247889

Identification of granzyme A isolated from cytotoxic T-lymphocyte-granules as one of the proteases encoded by CTL-specific genes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830180903247889

The ABCs of granule-mediated cytotoxicity: new weapons in the arsenal

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830180903247889

Synergistic roles of granzymes A and B in mediating target cell death by rat basophilic leukemia mast cell tumors also expressing cytolysin/perforin

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830180903247889

Extracellular activities of human granzymes. I. Granzyme A induces IL6 and IL8 production in fibroblast and epithelial cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830180903247889

Circulating concentrations of soluble granzyme A and B increase during natural and experimental Plasmodium falciparum infections

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830180903247889

Granzyme A released upon stimulation of cytotoxic T lymphocytes activates the thrombin receptor on neuronal cells and astrocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830180903247889

Activation of pro-urokinase by the human T cell-associated serine proteinase HuTSP-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830180903247889

Granzyme A cleaves a mitochondrial complex I protein to initiate caspase-independent cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830180903247889

HMG2 interacts with the nucleosome assembly protein SET and is a target of the cytotoxic T-lymphocyte protease granzyme A

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830180903247889

Tumor suppressor NM23-H1 is a granzyme A-activated DNase during CTL-mediated apoptosis, and the nucleosome assembly protein SET is its inhibitor

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830180903247889

Structural organization of the hCTLA-1 gene encoding human granzyme B.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830180903247889

The three-dimensional structure of human granzyme B compared to caspase-3, key mediators of cell death with cleavage specificity for aspartic acid in P1

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830180903247889

Crystal structure of the caspase activator human granzyme B, a proteinase highly specific for an Asp-P1 residue

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830180903247889

Characterization of structural determinants of granzyme B reveals potent mediators of extended substrate specificity

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830180903247889

Importance of the P4' residue in human granzyme B inhibitors and substrates revealed by scanning mutagenesis of the proteinase inhibitor 9 reactive center loop

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830180903247889

The structure of the pro-apoptotic protease granzyme B reveals the molecular determinants of its specificity

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830180903247889

Definition and redesign of the extended substrate specificity of granzyme B.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830180903247889

Granzyme B directly and efficiently cleaves several downstream caspase substrates: implications for CTL-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830180903247889

DFF45/ICAD can be directly processed by granzyme B during the induction of apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830180903247889

Cowpox virus CrmA, Myxoma virus SERP2 and baculovirus P35 are not functionally interchangeable caspase inhibitors in poxvirus infections

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830180903247889

Xenogeneic human NK cytotoxicity against porcine endothelial cells is perforin/granzyme B dependent and not inhibited by Bcl-2 overexpression

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830180903247889

The ratio of FOXP3+ regulatory T cells to granzyme B+ cytotoxic T/NK cells predicts prognosis in classical Hodgkin lymphoma and is independent of bcl-2 and MAL expression

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830180903247889

Granzyme B-mediated death of pancreatic beta-cells requires the proapoptotic BH3-only molecule bid.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830180903247889

Role of Bid-induced mitochondrial outer membrane permeabilization in granzyme B-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830180903247889

Granzyme B induces BID-mediated cytochrome c release and mitochondrial permeability transition

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830180903247889

Granzyme B-mediated cytochrome c release is regulated by the Bcl-2 family members bid and Bax.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830180903247889

Multiple apoptogenic proteins are involved in the nuclear translocation of Apoptosis Inducing Factor during transient focal cerebral ischemia in rat

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830180903247889

Manipulation of NK cytotoxicity by the IAP family member Livin

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830180903247889

Granzyme B can cause mitochondrial depolarization and cell death in the absence of BID, BAX, and BAK.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830180903247889

A central role for Bid in granzyme B-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830180903247889

Mitochondrial release of AIF and EndoG requires caspase activation downstream of Bax/Bak-mediated permeabilization

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830180903247889

Enhanced apoptosis of squamous cell carcinoma cells by interleukin-2-activated cytotoxic lymphocytes combined with radiation and anticancer drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830180903247889

The granzyme B-serglycin complex from cytotoxic granules requires dynamin for endocytosis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830180903247889

Cytotoxic cell granule-mediated apoptosis. Characterization of the macromolecular complex of granzyme B with serglycin

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830180903247889

Cytotoxic cell granule-mediated apoptosis: perforin delivers granzyme B-serglycin complexes into target cells without plasma membrane pore formation

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830180903247889

Granule-mediated killing by granzyme B and perforin requires a mannose 6-phosphate receptor and is augmented by cell surface heparan sulfate

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830180903247889

Cytotoxic T lymphocyte granules are secretory lysosomes, containing both perforin and granzymes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830180903247889

Granzymes A and B are targeted to the lytic granules of lymphocytes by the mannose-6-phosphate receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830180903247889

A functional role for the GCC185 golgin in mannose 6-phosphate receptor recycling

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830180903247889

Mannose 6-phosphate/insulin-like growth factor II receptor is a death receptor for granzyme B during cytotoxic T cell-induced apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830180903247889

Unimpaired allorejection of cells deficient for the mannose 6-phosphate receptors Mpr300 and Mpr46.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830180903247889

A clathrin/dynamin- and mannose-6-phosphate receptor-independent pathway for granzyme B-induced cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830180903247889

Granzyme A and B-deficient killer lymphocytes are defective in eliciting DNA fragmentation but retain potent in vivo anti-tumor capacity

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830180903247889

Control of lymphocytic choriomeningitis virus infection in granzyme B deficient mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830180903247889

Granzyme A is critical for recovery of mice from infection with the natural cytopathic viral pathogen, ectromelia

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830180903247889

Granzyme A, a noncytolytic component of CD8(+) cell granules, restricts the spread of herpes simplex virus in the peripheral nervous systems of experimentally infected mice

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830180903247889

The differential contribution of granzyme A and granzyme B in cytotoxic T lymphocyte-mediated apoptosis is determined by the quality of target cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830180903247889

Granzyme A induces caspase-independent mitochondrial damage, a required first step for apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830180903247889

Induction of rapid histone degradation by the cytotoxic T lymphocyte protease Granzyme A.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830180903247889

Granzymes A and B directly cleave lamins and disrupt the nuclear lamina during granule-mediated cytolysis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830180903247889

Nuclear war: the granzyme A-bomb

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830180903247889

Functional proteomics of resveratrol-induced colon cancer cell apoptosis: caspase-6-mediated cleavage of lamin A is a major signaling loop

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830180903247889

Caspase-6 gene disruption reveals a requirement for lamin A cleavage in apoptotic chromatin condensation

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830180903247889

Perforin-dependent nuclear targeting of granzymes: A central role in the nuclear events of granule-exocytosis-mediated apoptosis?

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830180903247889

Perforin-dependent nuclear entry of granzyme B precedes apoptosis, and is not a consequence of nuclear membrane dysfunction

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830180903247889

Death by a thousand cuts: granzyme pathways of programmed cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830180903247889

Functional significance of the perforin/granzyme cell death pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830180903247889

Cell death induced by granzyme C.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830180903247889

Nephritogenic T cells use granzyme C as a cytotoxic mediator

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830180903247889

Evaluation of cell death and proliferation in psoriatic epidermis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830180903247889

Residual cytotoxicity and granzyme K expression in granzyme A-deficient cytotoxic lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830180903247889

Granzyme K directly processes bid to release cytochrome c and endonuclease G leading to mitochondria-dependent cell death.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830180903247889

Granzyme K cleaves the nucleosome assembly protein SET to induce single-stranded DNA nicks of target cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830180903247889

The serine protease granzyme M is preferentially expressed in NK-cell, gamma delta T-cell, and intestinal T-cell lymphomas: evidence of origin from lymphocytes involved in innate immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830180903247889

Granzyme M mediates a novel form of perforin-dependent cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830180903247889

Granzyme K: a novel mediator in acute airway inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830180903247889

Human and mouse granzyme A induce a proinflammatory cytokine response.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830180903247889

Granzyme B is expressed in mouse mast cells in vivo and in vitro and causes delayed cell death independent of perforin.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830180903247889

Macrophages express granzyme B in the lesion areas of atherosclerosis and rheumatoid arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830180903247889

Notch2 integrates signaling by the transcription factors RBP-J and CREB1 to promote T cell cytotoxicity.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830180903247889

Decreased perforin and granzyme B expression in senescent HIV-1-specific cytotoxic T lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830180903247889

Cutting Edge: Granzyme B Proteolysis of a Neuronal Glutamate Receptor Generates an Autoantigen and Is Modulated by Glycosylation

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830180903247889

Filamin (280-kDa Actin-binding Protein) Is a Caspase Substrate and Is Also Cleaved Directly by the Cytotoxic T Lymphocyte Protease Granzyme B during Apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F08830180903247889

10.3109/08830180903247889

21 January 2018

Identifiers

DOI

1 reference

21 August 2017

1 reference