(Q37912174)

25 August 2017

1 reference

title

Is it possible to improve neurodevelopmental abnormalities in Down syndrome? (English)

1 reference

25 August 2017

Elisabetta Ciani

3

0 references

author name string

Renata Bartesaghi

series ordinal

1

1 reference

25 August 2017

Sandra Guidi

series ordinal

2

1 reference

25 August 2017

publication date

1 January 2011

1 reference

Reviews in the Neurosciences

25 August 2017

published in

1 reference

25 August 2017

volume

22

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25 August 2017

issue

4

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25 August 2017

page(s)

419-455

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Cell formation in the cortical layers of the developing human cerebellum.

25 August 2017

cites work

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Classification of human chromosome 21 gene-expression variations in Down syndrome: impact on disease phenotypes

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Neurodevelopmental delay, motor abnormalities and cognitive deficits in transgenic mice overexpressing Dyrk1A (minibrain), a murine model of Down's syndrome.

21 January 2018

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Increased NR2A expression and prolonged decay of NMDA-induced calcium transient in cerebellum of TgDyrk1A mice, a mouse model of Down syndrome.

21 January 2018

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Migration and distribution of two populations of hippocampal granule cell precursors during the perinatal and postnatal periods

21 January 2018

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Presenilin-dependent gamma-secretase-mediated control of p53-associated cell death in Alzheimer's disease.

21 January 2018

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Dosage-dependent over-expression of genes in the trisomic region of Ts1Cje mouse model for Down syndrome.

21 January 2018

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https://api.crossref.org/works/10.1515%2FRNS.2011.037

Chromosome 21 and down syndrome: from genomics to pathophysiology

21 January 2018

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https://api.crossref.org/works/10.1515%2FRNS.2011.037

Excessive expression of synaptojanin in brains with Down syndrome.

21 January 2018

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https://api.crossref.org/works/10.1515%2FRNS.2011.037

Characterization of a mouse model overexpressing beta-site APP-cleaving enzyme 2 reveals a new role for BACE2.

21 January 2018

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In vivo effects of APP are not exacerbated by BACE2 co-overexpression: behavioural characterization of a double transgenic mouse model.

21 January 2018

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https://api.crossref.org/works/10.1515%2FRNS.2011.037

Down's syndrome suppression of tumour growth and the role of the calcineurin inhibitor DSCR1

21 January 2018

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https://api.crossref.org/works/10.1515%2FRNS.2011.037

Neuronal target genes of the neuron-restrictive silencer factor in neurospheres derived from fetuses with Down's syndrome: a gene expression study

21 January 2018

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The specificities of protein kinase inhibitors: an update

21 January 2018

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https://api.crossref.org/works/10.1515%2FRNS.2011.037

Developmental and behavioral consequences of prenatal fluoxetine.

21 January 2018

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https://api.crossref.org/works/10.1515%2FRNS.2011.037

Biochemical studies on myelin isolated from the brains of patients with Down's syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

Constitutive overexpression of Cu/Zn superoxide dismutase exacerbates kainic acid-induced apoptosis of transgenic-Cu/Zn superoxide dismutase neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

Discovery and genetic localization of Down syndrome cerebellar phenotypes using the Ts65Dn mouse.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

Dendritic atrophy in children with Down's syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

Synaptic structural abnormalities in the Ts65Dn mouse model of Down Syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

Synaptic and cognitive abnormalities in mouse models of Down syndrome: exploring genotype-phenotype relationships

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

The "Down syndrome critical region" is sufficient in the mouse model to confer behavioral, neurophysiological, and synaptic phenotypes characteristic of Down syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

Excitatory-inhibitory relationship in the fascia dentata in the Ts65Dn mouse model of Down syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

Widespread changes in dendritic and axonal morphology in Mecp2-mutant mouse models of Rett syndrome: evidence for disruption of neuronal networks

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

Pulmonary and systemic nitric oxide measurements during CCK-5-induced panic attacks

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

On dendrites in Down syndrome and DS murine models: a spiny way to learn.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

Behavioral consequences of abnormal cortical development: insights into developmental disabilities

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

Ts65Dn, a mouse model of Down syndrome, exhibits increased GABAB-induced potassium current.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

A critical period in cortical interneuron neurogenesis in down syndrome revealed by human neural progenitor cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

Lithium restores neurogenesis in the subventricular zone of the Ts65Dn mouse, a model for Down syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

Early pharmacotherapy restores neurogenesis and cognitive performance in the Ts65Dn mouse model for Down syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

Frontal cortex BDNF levels correlate with working memory in an animal model of Down syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

Clinical potential of minocycline for neurodegenerative disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

Psychopharmacologic treatment of pediatric major depressive disorder

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

Roles of the mammalian subventricular zone in brain development

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

Apoptosis and increased generation of reactive oxygen species in Down's syndrome neurons in vitro.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

Altered metabolism of the amyloid beta precursor protein is associated with mitochondrial dysfunction in Down's syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

NAP and ADNF-9 protect normal and Down's syndrome cortical neurons from oxidative damage and apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

Characterization of transgenic mice with an increased content of chromosomal protein HMG-14 in their chromatin

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

Retrograde transport of neurotrophins: fact and function

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

A transcriptionally [correction of transcriptively] active complex of APP with Fe65 and histone acetyltransferase Tip60

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

Long-term memory in mental retardation: evidence for a specific impairment in subjects with Down's syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

Menopause in women with learning disabilities.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

Defects in embryonic neurogenesis and initial synapse formation in the forebrain of the Ts65Dn mouse model of Down syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

Olig1 and Olig2 triplication causes developmental brain defects in Down syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

The Drosophila homolog of Down's syndrome critical region 1 gene regulates learning: implications for mental retardation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

Grasping objects: the cortical mechanisms of visuomotor transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

Neurotrophin signalling in health and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

Behavioral phenotype of individuals with Down syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

Small molecule modulation of Smoothened activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

Dynamin is a minibrain kinase/dual specificity Yak1-related kinase 1A substrate

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

Tetracycline antibiotics: mode of action, applications, molecular biology, and epidemiology of bacterial resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

Uptake and distribution of catechins in fetal organs following in utero exposure in rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

Fluoxetine rescues deficient neurogenesis in hippocampus of the Ts65Dn mouse model for Down syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

Choline acetyltransferase activity at different ages in brain of Ts65Dn mice, an animal model for Down's syndrome and related neurodegenerative diseases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

Cell cycle alteration and decreased cell proliferation in the hippocampal dentate gyrus and in the neocortical germinal matrix of fetuses with Down syndrome and in Ts65Dn mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

Cell cycle elongation impairs proliferation of cerebellar granule cell precursors in the Ts65Dn mouse, an animal model for Down syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

Failed retrograde transport of NGF in a mouse model of Down's syndrome: reversal of cholinergic neurodegenerative phenotypes following NGF infusion

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

Infantile spasms and Down syndrome: a new animal model

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

Motor dysfunction in a mouse model for Down syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

The neurobiologic consequences of Down syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

The cerebellar transcriptome during postnatal development of the Ts1Cje mouse, a segmental trisomy model for Down syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

Spatial memory deficits in segmental trisomic Ts65Dn mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

Alterations of central noradrenergic transmission in Ts65Dn mouse, a model for Down syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

Murine models for Down syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

Alterations of neocortical pyramidal cell phenotype in the Ts65Dn mouse model of Down syndrome: effects of environmental enrichment

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

Effects of memantine on neuronal structure and conditioned fear in the Tg2576 mouse model of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

In vivo restoration of physiological levels of truncated TrkB.T1 receptor rescues neuronal cell death in a trisomic mouse model.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

Supplementation with antioxidants and folinic acid for children with Down's syndrome: randomised controlled trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

Fluoxetine targets early progenitor cells in the adult brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

Aberrant protein expression in cerebral cortex of fetus with Down syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

Episodic-like memory in Ts65Dn, a mouse model of Down syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

Normal protein composition of synapses in Ts65Dn mice: a mouse model of Down syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

Attenuation of Notch signalling by the Down-syndrome-associated kinase DYRK1A.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

Neonatal handling and environmental enrichment effects on emotionality, novelty/reward seeking, and age-related cognitive and hippocampal impairments: focus on the Roman rat lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

Down's syndrome and Alzheimer's disease: dendritic spine counts in the hippocampus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

Activation of the Notch pathway in Down syndrome: cross-talk of Notch and APP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

Phase 2 safety trial targeting amyloid beta production with a gamma-secretase inhibitor in Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

Small-molecule modulators of Hedgehog signaling: identification and characterization of Smoothened agonists and antagonists

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

A new human gene from the Down syndrome critical region encodes a proline-rich protein highly expressed in fetal brain and heart

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

DSCR1, overexpressed in Down syndrome, is an inhibitor of calcineurin-mediated signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

Stimulated neuronal expression of brain-derived neurotrophic factor by Neurotropin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

Reversible impairment of long-term potentiation in transgenic Cu/Zn-SOD mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

Impairments in motor coordination without major changes in cerebellar plasticity in the Tc1 mouse model of Down syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

Understanding mental retardation in Down's syndrome using trisomy 16 mouse models

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

Pathology of the auditory system in autosomal trisomies with morphometric and quantitative study of the ventral cochlear nucleus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

Oxidative stress and hematologic and biochemical parameters in individuals with Down syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

A gamma-secretase inhibitor blocks Notch signaling in vivo and causes a severe neurogenic phenotype in zebrafish

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

APP Intracellular Domain Impairs Adult Neurogenesis in Transgenic Mice by Inducing Neuroinflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

Alzheimer-like neurotransmitter deficits in adult Down's syndrome brain tissue

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

Development of the superior temporal neocortex is anomalous in trisomy 21.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

NAP: research and development of a peptide derived from activity-dependent neuroprotective protein (ADNP).

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

NAP and D-SAL: neuroprotection against the beta amyloid peptide (1-42)

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

Loss of cholinergic phenotype in basal forebrain coincides with cognitive decline in a mouse model of Down's syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

Estrogen restores cognition and cholinergic phenotype in an animal model of Down syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

Estrogen alters amyloid precursor protein as well as dendritic and cholinergic markers in a mouse model of Down syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

Effects of rearing complexity on dendritic branching in frontolateral and temporal cortex of the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

Effects of unilateral and bilateral training in a reaching task on dendritic branching of neurons in the rat motor-sensory forelimb cortex

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

Brain interleukin 1 and S-100 immunoreactivity are elevated in Down syndrome and Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

Life-long overexpression of S100beta in Down's syndrome: implications for Alzheimer pathogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

Systematic approach to the study of trisomy in the mouse. II

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

Green tea polyphenols rescue of brain defects induced by overexpression of DYRK1A.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

Neurogenesis impairment and increased cell death reduce total neuron number in the hippocampal region of fetuses with Down syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

Widespread proliferation impairment and hypocellularity in the cerebellum of fetuses with down syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

Human minibrain homologue (MNBH/DYRK1): characterization, alternative splicing, differential tissue expression, and overexpression in Down syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

Aberrant expression of centractin and capping proteins, integral constituents of the dynactin complex, in fetal down syndrome brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

Expression patterns and subcellular localization of the Down syndrome candidate protein MNB/DYRK1A suggest a role in late neuronal differentiation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

Abnormal expression of the G-protein-activated inwardly rectifying potassium channel 2 (GIRK2) in hippocampus, frontal cortex, and substantia nigra of Ts65Dn mouse: a model of Down syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

Functional and morphological alterations in compound transgenic mice overexpressing Cu/Zn superoxide dismutase and amyloid precursor protein [correction].

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

ets-2 promotes the activation of a mitochondrial death pathway in Down's syndrome neurons.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

Gene network disruptions and neurogenesis defects in the adult Ts1Cje mouse model of Down syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

Developmental abnormalities and age-related neurodegeneration in a mouse model of Down syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

Minocycline prevents cholinergic loss in a mouse model of Down's syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

Prevention of learning deficit in a Down syndrome model.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

Cellular and molecular basis of estrogen's neuroprotection. Potential relevance for Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

Safety studies on epigallocatechin gallate (EGCG) preparations. Part 1: genotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

Increased lipid peroxidation in Down's syndrome mouse models.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

Enlarged brain ventricles and impaired neurogenesis in the Ts1Cje and Ts2Cje mouse models of Down syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

Ginkgo biloba in Alzheimer's disease: a systematic review

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

Beta-amyloid (1-42)-induced learning and memory deficits in mice: involvement of oxidative burdens in the hippocampus and cerebral cortex

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

Biomarkers of oxidative stress are significantly elevated in Down syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

Cholinesterase inhibitors for patients with Alzheimer's disease: systematic review of randomised clinical trials

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

Transcript level alterations reflect gene dosage effects across multiple tissues in a mouse model of down syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

Hedgehog target genes: mechanisms of carcinogenesis induced by aberrant hedgehog signaling activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

Neuroendocrine-specific protein C, a marker of neuronal differentiation, is reduced in brain of patients with Down syndrome and Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

Overexpression of Dyrk1A causes the defects in synaptic vesicle endocytosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

Hippocampal long-term potentiation suppressed by increased inhibition in the Ts65Dn mouse, a genetic model of Down syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

Magnetic resonance imaging evaluation of delayed myelination in Down syndrome: a case report and review of the literature

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

Down syndrome phenotypes: the consequences of chromosomal imbalance

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

Synaptic deficit in the temporal cortex of partial trisomy 16 (Ts65Dn) mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

Deficits of neuronal density in CA1 and synaptic density in the dentate gyrus, CA3 and CA1, in a mouse model of Down syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

Sonic hedgehog regulates adult neural progenitor proliferation in vitro and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

Duplication of the entire 22.9 Mb human chromosome 21 syntenic region on mouse chromosome 16 causes cardiovascular and gastrointestinal abnormalities.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

Regulation of NMDA channel function by endogenous Ca(2+)-dependent phosphatase

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

Cholinergic degeneration and memory loss delayed by vitamin E in a Down syndrome mouse model.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

Effects of long-term memantine on memory and neuropathology in Ts65Dn mice, a model for Down syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

Hippocampal hypocellularity in the Ts65Dn mouse originates early in development

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

Notch signalling in vertebrate neural development

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

Manifold reduction of moesin in fetal Down syndrome brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

G protein-coupled inwardly rectifying K+ channels (GIRKs) mediate postsynaptic but not presynaptic transmitter actions in hippocampal neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

Gene expression from the aneuploid chromosome in a trisomy mouse model of down syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

Genotype-phenotype correlations in Down syndrome identified by array CGH in 30 cases of partial trisomy and partial monosomy chromosome 21

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

Antidepressant action: to the nucleus and beyond

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

Calcineurin in memory and bidirectional plasticity

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

Global up-regulation of chromosome 21 gene expression in the developing down syndrome brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

Pyramidal cell abnormalities in the motor cortex of a child with Down's syndrome. A Golgi study

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

Differential effects of environmental enrichment on behavior and learning of male and female Ts65Dn mice, a model for Down syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

Behavioral, cognitive and biochemical responses to different environmental conditions in male Ts65Dn mice, a model of Down syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

The nerve growth factor family of receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

The rat trk protooncogene product exhibits properties characteristic of the slow nerve growth factor receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

Cholinergic, serotonergic and catecholaminergic neurons are not affected in Ts65Dn mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

Developmental changes of S-100 protein and glial fibrillary acidic protein in the brain in Down syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

Proliferation deficits and gene expression dysregulation in Down's syndrome (Ts1Cje) neural progenitor cells cultured from neurospheres

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

The effects of piracetam on cognitive performance in a mouse model of Down's syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

Preservation of long-term memory and synaptic plasticity despite short-term impairments in the Tc1 mouse model of Down syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

Transient Notch activation initiates an irreversible switch from neurogenesis to gliogenesis by neural crest stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

Neuroscience: Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

The amyloid precursor protein intracellular domain (AICD) as modulator of gene expression, apoptosis, and cytoskeletal dynamics-relevance for Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

A distinct role for norepinephrine in memory retrieval

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

Down's syndrome: a genetic disorder in biobehavioral perspective

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

Lowering beta-amyloid levels rescues learning and memory in a Down syndrome mouse model

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

An aneuploid mouse strain carrying human chromosome 21 with Down syndrome phenotypes

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

On the occurrence of neuronal sprouting in the frontal cortex of a patient with Down's syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

A chromosome 21 critical region does not cause specific Down syndrome phenotypes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

Down syndrome mouse models Ts65Dn, Ts1Cje, and Ms1Cje/Ts65Dn exhibit variable severity of cerebellar phenotypes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

Trisomy for the Down syndrome 'critical region' is necessary but not sufficient for brain phenotypes of trisomic mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

Sonic hedgehog controls stem cell behavior in the postnatal and adult brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

Dyrk1A overexpression in immortalized hippocampal cells produces the neuropathological features of Down syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

Dyrk1A phosphorylates p53 and inhibits proliferation of embryonic neuronal cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

GVS-111 prevents oxidative damage and apoptosis in normal and Down's syndrome human cortical neurons.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

Red cell superoxide dismutase, glutathione peroxidase and catalase in Down syndrome patients with and without manifestations of Alzheimer disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

A new mouse model for the trisomy of the Abcg1-U2af1 region reveals the complexity of the combinatorial genetic code of down syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

Alteration of inhibitory circuits in the somatosensory cortex of Ts65Dn mice, a model for Down's syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

Learning from NMDA receptor trafficking: clues to the development and maturation of glutamatergic synapses

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

Differential contribution of amygdala and hippocampus to cued and contextual fear conditioning

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

Neuroanatomy of Down's syndrome: a high-resolution MRI study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

Abnormal expression of synaptic proteins and neurotrophin-3 in the Down syndrome mouse model Ts65Dn

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

Three-dimensional synaptic ultrastructure in the dentate gyrus and hippocampal area CA3 in the Ts65Dn mouse model of Down syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

RCAN1 (DSCR1) increases neuronal susceptibility to oxidative stress: a potential pathogenic process in neurodegeneration.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

Mental retardation and associated neurological dysfunctions in Down syndrome: a consequence of dysregulation in critical chromosome 21 genes and associated molecular pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

A mouse model for Down syndrome exhibits learning and behaviour deficits.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

Trophic actions of GABA on neuronal development

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

Parallels of craniofacial maldevelopment in Down syndrome and Ts65Dn mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

Excitatory amino acids and monoamines in parahippocampal gyrus and frontal cortical pole of adults with Down syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

A role for neurotrophin-3 in targeting developing cholinergic axon projections to cerebral cortex

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

Defective cerebellar response to mitogenic Hedgehog signaling in Down [corrected] syndrome mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

Effects of chronic administration of SGS-111 during adulthood and during the pre- and post-natal periods on the cognitive deficits of Ts65Dn mice, a model of Down syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

Dual-specificity tyrosine(Y)-phosphorylation regulated kinase 1A-mediated phosphorylation of amyloid precursor protein: evidence for a functional link between Down syndrome and Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

Ts1Cje, a partial trisomy 16 mouse model for Down syndrome, exhibits learning and behavioral abnormalities

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

Genetic dissection of region associated with behavioral abnormalities in mouse models for Down syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

Neonatal mice of the Down syndrome model, Ts65Dn, exhibit upregulated VIP measures and reduced responsiveness of cortical astrocytes to VIP stimulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

Brain-derived neurotrophic factor and antidepressant drugs have different but coordinated effects on neuronal turnover, proliferation, and survival in the adult dentate gyrus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

Increased App expression in a mouse model of Down's syndrome disrupts NGF transport and causes cholinergic neuron degeneration.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

Requirement of hippocampal neurogenesis for the behavioral effects of antidepressants

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

Aberrant expression of bcl-2 gene family in Down's syndrome brains.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

Comparative coherence studies in healthy volunteers and Down's syndrome patients from childhood to adult age

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

Caspases as treatment targets in stroke and neurodegenerative diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

Neural activity regulates synaptic properties and dendritic structure in vivo through calcineurin/NFAT signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

Ets target genes: past, present and future

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

Abnormal APP, cholinergic and cognitive function in Ts65Dn Down's model mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

Fatty acid composition of lipids of human brain myelin and synaptosomes: Changes in phenylketonuria and down's syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

Discovery of novel hippocampal neurogenic agents by using an in vivo stable isotope labeling technique.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

α-Tocopherol suppresses lipid peroxidation and behavioral and cognitive impairments in the Ts65Dn mouse model of Down syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

Derangement of hypothetical proteins in fetal Down's syndrome brain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

Prevalence of Down syndrome among children and adolescents in 10 regions of the United States

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

Mitochondrial dysfunction and tau hyperphosphorylation in Ts1Cje, a mouse model for Down syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

Molecular responses of the Ts65Dn and Ts1Cje mouse models of Down syndrome to MK-801.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

Neuronal migration, with special reference to developing human brain: a review

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

Construction of a panel of transgenic mice containing a contiguous 2-Mb set of YAC/P1 clones from human chromosome 21q22.2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

Functional screening of 2 Mb of human chromosome 21q22.2 in transgenic mice implicates minibrain in learning defects associated with Down syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

Nerve growth factor signaling, neuroprotection, and neural repair

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

Isolation of human and murine homologues of the Drosophila minibrain gene: human homologue maps to 21q22.2 in the Down syndrome "critical region"

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

Activation of caspase-3 in single neurons and autophagic granules of granulovacuolar degeneration in Alzheimer's disease. Evidence for apoptotic cell death.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

Experimental parameters affecting the Morris water maze performance of a mouse model of Down syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

Chronobiometry of behavioral activity in the Ts65Dn model of Down syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

Cerebellum morphogenesis: the foliation pattern is orchestrated by multi-cellular anchoring centers

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

Spine distribution along the apical dendrites of the pyramidal neurons in Down's syndrome. A quantitative Golgi study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

Down's syndrome-like skeletal abnormalities in Ets2 transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

Abnormal neuronal development in the visual cortex of the human fetus and infant with down's syndrome. A quantitative and qualitative Golgi study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

H2O2 and 4-hydroxynonenal mediate amyloid beta-induced neuronal apoptosis by activating JNKs and p38MAPK.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

Relation of corpus callosum and hippocampal size to age in nondemented adults with Down's syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

Engineering DYRK1A overdosage yields Down syndrome-characteristic cortical splicing aberrations.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

Prevention of developmental delays in a Down syndrome mouse model

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

APP-dependent up-regulation of Ptch1 underlies proliferation impairment of neural precursors in Down syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

Segmental trisomy of chromosome 17: a mouse model of human aneuploidy syndromes

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

Motor development and neuropsychological patterns in persons with Down syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

Identification and characterization of a new Down syndrome model, Ts[Rb(12.1716)]2Cje, resulting from a spontaneous Robertsonian fusion between T(171)65Dn and mouse chromosome 12.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

Synaptojanin 1-linked phosphoinositide dyshomeostasis and cognitive deficits in mouse models of Down's syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

Perinatal growth of prefrontal layer III pyramids in Down syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

Chronic fluoxetine stimulates maturation and synaptic plasticity of adult-born hippocampal granule cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

The role of overexpressed DYRK1A protein in the early onset of neurofibrillary degeneration in Down syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

Reduction of actin-related protein complex 2/3 in fetal Down syndrome brain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

Mechanisms to prevent the toxicity of chronic neuroinflammation on forebrain cholinergic neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

Lithium regulates adult hippocampal progenitor development through canonical Wnt pathway activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

Serotonin and brain development: role in human developmental diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

A voxel-based morphometric study of nondemented adults with Down Syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

Fetal Down syndrome brains exhibit aberrant levels of neurotransmitters critical for normal brain development

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

Piracetam: a review of pharmacological properties and clinical uses.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

Occurrence of neuropathological changes and dementia of Alzheimer's disease in Down's syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

ETS2 overexpression in transgenic models and in Down syndrome predisposes to apoptosis via the p53 pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

Promotion of neuronal plasticity by (-)-epigallocatechin-3-gallate

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

Dyrk1A overexpression inhibits proliferation and induces premature neuronal differentiation of neural progenitor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

Protein kinase Dyrk1 activates cAMP response element-binding protein during neuronal differentiation in hippocampal progenitor cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

A mouse model of Down syndrome trisomic for all human chromosome 21 syntenic regions

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

Forebrain-specific calcineurin knockout selectively impairs bidirectional synaptic plasticity and working/episodic-like memory

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

Mice trisomic for a bacterial artificial chromosome with the single-minded 2 gene (Sim2) show phenotypes similar to some of those present in the partial trisomy 16 mouse models of Down syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1515%2FRNS.2011.037

21 January 2018

Identifiers

DOI

10.1515/RNS.2011.037

1 reference

25 August 2017

1 reference