(Q37946306)

25 August 2017

Amyloid-β production: major link between oxidative stress and BACE1. (English)

1 reference

25 August 2017

4

Massimo Tabaton

1 reference

25 August 2017

Elena Tamagno

1

1 reference

PubMed ID

22002808

25 August 2017

Michela Guglielmotto

series ordinal

2

1 reference

PubMed ID

22002808

25 August 2017

Debora Monteleone

series ordinal

3

1 reference

25 August 2017

15 October 2011

1 reference

25 August 2017

Neurotoxicity Research

1 reference

25 August 2017

22

1 reference

25 August 2017

3

1 reference

25 August 2017

208-219

1 reference

https://scigraph.springernature.com/pub.10.1007/s12640-011-9283-6

25 August 2017

0 references

cites work

Age-associated changes in protein oxidation and proteasome activities in rat brain: modulation by antioxidants

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9283-6

Inflammation and Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9283-6

Beta-amyloid mediated nitration of manganese superoxide dismutase: implication for oxidative stress in a APPNLH/NLH X PS-1P264L/P264L double knock-in mouse model of Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9283-6

JNK/SAPK activation by platelet-derived growth factor in A431 cells requires both the phospholipase C-gamma and the phosphatidylinositol 3-kinase signaling pathways of the receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9283-6

Cerebral hemorrhage and amyloid-beta.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9283-6

Incidence of dementia and probable Alzheimer's disease in a general population: the Framingham Study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9283-6

21 January 2018

Free radicals and aging.

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9283-6

Antioxidant neuroprotection in Alzheimer's disease as preventive and therapeutic approach

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9283-6

The Qo site of the mitochondrial complex III is required for the transduction of hypoxic signaling via reactive oxygen species production

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9283-6

The increased activity of BACE1 correlates with oxidative stress in Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9283-6

Differential regulation of BACE1 promoter activity by nuclear factor-kappaB in neurons and glia upon exposure to beta-amyloid peptides

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9283-6

LRP in amyloid-beta production and metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9283-6

Advanced glycosylation: chemistry, biology, and implications for diabetes and aging

21 January 2018

2 references

https://api.crossref.org/works/10.1007%2FS12640-011-9283-6

21 January 2018

12 December 2020

NFkappaB-dependent control of BACE1 promoter transactivation by Abeta42.

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9283-6

Evidence of oxidative damage in Alzheimer's disease brain: central role for amyloid beta-peptide

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9283-6

Mitochondrial reactive oxygen species trigger hypoxia-induced transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9283-6

The induction of amyloid precursor protein and alpha-synuclein in rat hippocampal astrocytes by diethyldithiocarbamate and copper with or without glutathione

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9283-6

Disrupted intracellular calcium regulates BACE1 gene expression via nuclear factor of activated T cells 1 (NFAT 1) signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9283-6

RAGE regulates BACE1 and Abeta generation via NFAT1 activation in Alzheimer's disease animal model.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9283-6

Transcriptional regulation of BACE1, the beta-amyloid precursor protein beta-secretase, by Sp1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9283-6

Transgenic mice with Alzheimer presenilin 1 mutations show accelerated neurodegeneration without amyloid plaque formation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9283-6

Mutation of the beta-amyloid precursor protein in familial Alzheimer's disease increases beta-protein production

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9283-6

Mutant presenilins of Alzheimer's disease increase production of 42-residue amyloid beta-protein in both transfected cells and transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9283-6

JNK regulates APP cleavage and degradation in a model of Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9283-6

Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9283-6

Exclusively targeting beta-secretase to lipid rafts by GPI-anchor addition up-regulates beta-site processing of the amyloid precursor protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9283-6

Mitochondrial DNA deletions in human brain: regional variability and increase with advanced age

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9283-6

Involvement of oxidative stress-induced abnormalities in ceramide and cholesterol metabolism in brain aging and Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9283-6

Calcium signaling and amyloid toxicity in Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9283-6

L-theanine protects the APP (Swedish mutation) transgenic SH-SY5Y cell against glutamate-induced excitotoxicity via inhibition of the NMDA receptor pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9283-6

Molecular basis of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9283-6

Increased amyloid-beta42(43) in brains of mice expressing mutant presenilin 1

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9283-6

Cholesterol and APOE genotype interact to influence Alzheimer disease progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9283-6

FAD mutant PS-1 gene-targeted mice: increased A beta 42 and A beta deposition without APP overproduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9283-6

Oxidative stress in brain aging. Implications for therapeutics of neurodegenerative diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9283-6

Oxidative stress increases production of beta-amyloid precursor protein and beta-amyloid (Abeta) in mammalian lenses, and Abeta has toxic effects on lens epithelial cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9283-6

Presenilin-dependent gamma-secretase on plasma membrane and endosomes is functionally distinct.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9283-6

Beta-secretase protein and activity are increased in the neocortex in Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9283-6

Interaction between 24-hydroxycholesterol, oxidative stress, and amyloid-β in amplifying neuronal damage in Alzheimer's disease: three partners in crime.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9283-6

Mutant presenilin 1 increases the expression and activity of BACE1

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9283-6

Alzheimer's disease-affected brain: presence of oligomeric A beta ligands (ADDLs) suggests a molecular basis for reversible memory loss

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9283-6

Inflammation and NF-kappaB in Alzheimer's disease and diabetes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9283-6

The up-regulation of BACE1 mediated by hypoxia and ischemic injury: role of oxidative stress and HIF1alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9283-6

Oxidative imbalance in patients with mild cognitive impairment and Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9283-6

Amyloid deposition as the central event in the aetiology of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9283-6

Free radical theory of aging

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9283-6

Involvement of c-Jun N-terminal kinase in amyloid precursor protein-mediated neuronal cell death.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9283-6

A model for beta-amyloid aggregation and neurotoxicity based on free radical generation by the peptide: relevance to Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9283-6

Increased expression of the amyloid precursor beta-secretase in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9283-6

Cu(II) potentiation of alzheimer abeta neurotoxicity. Correlation with cell-free hydrogen peroxide production and metal reduction.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9283-6

Pravastatin at 10 mg/day does not decrease plasma levels of either amyloid-β (Aβ) 40 or Aβ 42 in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9283-6

Functional role of lipoprotein receptors in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9283-6

The pathology of ischemic-vascular dementia: an update

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9283-6

Statins and the risk of dementia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9283-6

Evidence that gamma-secretase mediates oxidative stress-induced beta-secretase expression in Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9283-6

Therapeutic potential of statins in Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9283-6

BACE1 Suppression by RNA Interference in Primary Cortical Neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9283-6

Common structure of soluble amyloid oligomers implies common mechanism of pathogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9283-6

Evidence of increased oxidative damage in subjects with mild cognitive impairment.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9283-6

The unsolved relationship of brain aging and late-onset Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9283-6

Mitochondrial complex III regulates hypoxic activation of HIF.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9283-6

Specific spatial learning deficits become severe with age in beta -amyloid precursor protein transgenic mice that harbor diffuse beta -amyloid deposits but do not form plaques

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9283-6

Formation of phospho-SAPK/JNK granules in the hippocampus is an early event in Alzheimer disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9283-6

The E280A presenilin 1 Alzheimer mutation produces increased A beta 42 deposition and severe cerebellar pathology.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9283-6

A specific amyloid-beta protein assembly in the brain impairs memory

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9283-6

Ratio of 8-hydroxyguanine in intact DNA to free 8-hydroxyguanine is increased in Alzheimer disease ventricular cerebrospinal fluid

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9283-6

Cholesterol homeostasis in human brain: evidence for an age-dependent flux of 24S-hydroxycholesterol from the brain into the circulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9283-6

Four-hydroxynonenal, a product of lipid peroxidation, is increased in the brain in Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9283-6

Lipid peroxidation is an early event in the brain in amnestic mild cognitive impairment.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9283-6

Dysregulation of SREBP2 induces BACE1 expression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9283-6

Lipids and the pathogenesis of Alzheimer's disease: is there a link?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9283-6

Essential roles for Fe65, Alzheimer amyloid precursor-binding protein, in the cellular response to DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9283-6

Oxidative stress induces intracellular accumulation of amyloid beta-protein (Abeta) in human neuroblastoma cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9283-6

Antioxidants as treatment for neurodegenerative disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9283-6

Formation and stabilization model of the 42-mer Abeta radical: implications for the long-lasting oxidative stress in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9283-6

Membrane-mediated amyloidogenesis and the promotion of oxidative lipid damage by amyloid beta proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9283-6

Coffee and Maillard products activate NF-kappaB in macrophages via H2O2 production

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9283-6

Neuronal RNA oxidation in Alzheimer's disease and Down's syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9283-6

Oxidative damage is the earliest event in Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9283-6

c-Jun N-terminal kinase (JNK) positively regulates NFATc2 transactivation through phosphorylation within the N-terminal regulatory domain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9283-6

Total cholesterol levels and the risk of mild cognitive impairment and Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9283-6

Palmitic acid-treated astrocytes induce BACE1 upregulation and accumulation of C-terminal fragment of APP in primary cortical neurons.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9283-6

Oxidative damage in Alzheimer's disease: the metabolic dimension

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9283-6

Oxidative stress hypothesis in Alzheimer's disease: a reappraisal

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9283-6

Alzheimer's disease: the cholesterol connection

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9283-6

Expression of the receptor for advanced glycation end products in oligodendrocytes in response to oxidative stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9283-6

Neurotoxic effect of oligomeric and fibrillar species of amyloid-beta peptide 1-42: involvement of endoplasmic reticulum calcium release in oligomer-induced cell death.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9283-6

The role of vascular factors in late-onset sporadic Alzheimer's disease. Genetic and molecular aspects.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9283-6

Aging affects oxidative state in hippocampus, hypothalamus and adrenal glands of Wistar rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9283-6

Nonsteroidal anti-inflammatory drugs repress beta-secretase gene promoter activity by the activation of PPARgamma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9283-6

Mechanisms of neurotoxicity associated with amyloid beta deposition and the role of free radicals in the pathogenesis of Alzheimer's disease: a critical appraisal

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9283-6

Relation of cerebral infarctions to dementia and cognitive function in older persons

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9283-6

Role of by-products of lipid oxidation in Alzheimer's disease brain: a focus on acrolein

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9283-6

Advanced Maillard reaction end products are associated with Alzheimer disease pathology

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9283-6

Plasma biomarkers for mild cognitive impairment and Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9283-6

Oxidatively modified proteins in Alzheimer's disease (AD), mild cognitive impairment and animal models of AD: role of Abeta in pathogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9283-6

Hypoxia facilitates Alzheimer's disease pathogenesis by up-regulating BACE1 gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9283-6

Hydrogen peroxide is generated during the very early stages of aggregation of the amyloid peptides implicated in Alzheimer disease and familial British dementia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9283-6

Processes of beta-amyloid and intracellular cytoplasmic domain generation by presenilin/gamma-secretase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9283-6

Alternative routes for the formation of immunochemically distinct advanced glycation end-products in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9283-6

Oxidative stress increases expression and activity of BACE in NT2 neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9283-6

Dehydroepiandrosterone reduces expression and activity of BACE in NT2 neurons exposed to oxidative stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9283-6

Beta-site APP cleaving enzyme up-regulation induced by 4-hydroxynonenal is mediated by stress-activated protein kinases pathways.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9283-6

The various aggregation states of beta-amyloid 1-42 mediate different effects on oxidative stress, neurodegeneration, and BACE-1 expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9283-6

Oxidative stress potentiates BACE1 gene expression and Abeta generation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9283-6

Mitochondrial formation of reactive oxygen species

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9283-6

Silent brain infarcts and the risk of dementia and cognitive decline.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9283-6

Excitotoxicity through Ca2+-permeable AMPA receptors requires Ca2+-dependent JNK activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9283-6

Advanced glycation end products contribute to amyloidosis in Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9283-6

Increased oxidative damage in nuclear and mitochondrial DNA in Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9283-6

Transcriptional regulation of beta-secretase by p25/cdk5 leads to enhanced amyloidogenic processing

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9283-6

Cholesterol and the biology of Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9283-6

IL-1beta induces MMP-9 expression via a Ca2+-dependent CaMKII/JNK/c-JUN cascade in rat brain astrocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9283-6

Glycated tau protein in Alzheimer disease: a mechanism for induction of oxidant stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9283-6

Non-enzymatically glycated tau in Alzheimer's disease induces neuronal oxidant stress resulting in cytokine gene expression and release of amyloid beta-peptide.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9283-6

RAGE and amyloid-beta peptide neurotoxicity in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9283-6

Elevated beta-secretase expression and enzymatic activity detected in sporadic Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9283-6

Mechanisms of neuronal degeneration in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9283-6

Phosphorylation of microtubule-associated protein tau by isoforms of c-Jun N-terminal kinase (JNK).

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9283-6

Hypoxia-inducible factor 1alpha (HIF-1alpha)-mediated hypoxia increases BACE1 expression and beta-amyloid generation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9283-6

Beta-site amyloid precursor protein cleaving enzyme 1 levels become elevated in neurons around amyloid plaques: implications for Alzheimer's disease pathogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9283-6

Oxidative stress and neuronal adaptation in Alzheimer disease: the role of SAPK pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9283-6

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9283-6

Oxidative stress induces increase in intracellular amyloid beta-protein production and selective activation of betaI and betaII PKCs in NT2 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12640-011-9283-6

JKK1, an upstream activator of JNK/SAPK, is activated in Alzheimer's disease.

21 January 2018

2 references

https://api.crossref.org/works/10.1007%2FS12640-011-9283-6

21 January 2018

12 December 2020

Analysis of microtubule-associated protein tau glycation in paired helical filaments.

1 reference

12 December 2020

Generation of an apoptotic intracellular peptide by gamma-secretase cleavage of Alzheimer's amyloid beta protein precursor.

1 reference

12 December 2020

Cytotoxic effects of autoxidative glycation

1 reference

12 December 2020

An iron-responsive element type II in the 5'-untranslated region of the Alzheimer's amyloid precursor protein transcript

1 reference

12 December 2020

Expression of stress-activated kinases c-Jun N-terminal kinase (SAPK/JNK-P) and p38 kinase (p38-P), and tau hyperphosphorylation in neurites surrounding betaA plaques in APP Tg2576 mice

1 reference

12 December 2020

The TAT-JNK inhibitor peptide interferes with beta amyloid protein stability

1 reference

12 December 2020

A role for 4-hydroxynonenal, an aldehydic product of lipid peroxidation, in disruption of ion homeostasis and neuronal death induced by amyloid beta-peptide.

1 reference

12 December 2020

Oxidative stress activates a positive feedback between the gamma- and beta-secretase cleavages of the beta-amyloid precursor protein

1 reference

12 December 2020

Oxidative alterations in Alzheimer's disease.

1 reference

12 December 2020

Effects of simvastatin on cholesterol metabolism and Alzheimer disease biomarkers.

1 reference

12 December 2020

In vitro and in vivo oxidative stress associated with Alzheimer's amyloid beta-peptide (1-42)

1 reference

12 December 2020

The expression of p75 neurotrophin receptor protects against the neurotoxicity of soluble oligomers of beta-amyloid

1 reference

12 December 2020

AGEs/RAGE complex upregulates BACE1 via NF-κB pathway activation.

1 reference

12 December 2020

1 reference

12 December 2020

Advanced products of nonenzymatic glycosylation and the pathogenesis of diabetic vascular disease

1 reference

12 December 2020

Molecular mechanisms initiating amyloid beta-fibril formation in Alzheimer's disease.

1 reference

12 December 2020

A cyclic peptide that binds p75(NTR) protects neurones from beta amyloid (1-40)-induced cell death.

1 reference

12 December 2020

Cloning and expression of a cell surface receptor for advanced glycosylation end products of proteins

1 reference

12 December 2020

Immunohistochemical evidence of oxidative [corrected] stress in Alzheimer's disease

1 reference

12 December 2020

Tyrosine gated electron transfer is key to the toxic mechanism of Alzheimer's disease beta-amyloid

1 reference

12 December 2020

Oxidative stress in Alzheimer's disease: implications for prevention and therapy.

1 reference

12 December 2020

Gene structure and organization of the human beta-secretase (BACE) promoter.

1 reference

12 December 2020

Immunization reverses memory deficits without reducing brain Abeta burden in Alzheimer's disease model.

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12 December 2020

Roles of lipid peroxidation in modulation of cellular signaling pathways, cell dysfunction, and death in the nervous system

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12 December 2020

Amyloid-β₄₂ activates the expression of BACE1 through the JNK pathway

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12 December 2020

10.1007/S12640-011-9283-6

Identifiers

DOI

1 reference

25 August 2017

1 reference

PubMed ID

22002808