(Q38173847)

30 August 2017

title

p21-Activated protein kinases and their emerging roles in glucose homeostasis (English)

1 reference

30 August 2017

Yu-ting Alex Chiang

1

1 reference

30 August 2017

Tianru Jin

series ordinal

2

1 reference

30 August 2017

publication date

24 December 2013

1 reference

American Journal of Physiology - Endocrinology and Metabolism

30 August 2017

published in

1 reference

30 August 2017

volume

306

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30 August 2017

issue

7

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30 August 2017

page(s)

E707-22

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PAK4, a novel effector for Cdc42Hs, is implicated in the reorganization of the actin cytoskeleton and in the formation of filopodia

30 August 2017

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Phosphorylated Pak1 level in the cytoplasm correlates with shorter survival time in patients with glioblastoma

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Pak1 kinase links ErbB2 to β-catenin in transformation of breast epithelial cells

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Non-muscle myosin IIA is involved in focal adhesion and actin remodelling controlling glucose-stimulated insulin secretion

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Identification of a mouse p21Cdc42/Rac activated kinase

21 January 2018

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Functional interactions between the estrogen receptor coactivator PELP1/MNAR and retinoblastoma protein

21 January 2018

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Role of group A p21-activated kinases in activation of extracellular-regulated kinase by growth factors

21 January 2018

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Insulin and IGFs in obesity-related breast cancer

21 January 2018

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21 January 2018

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Interaction of the Nck adapter protein with p21-activated kinase (PAK1)

21 January 2018

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Disruption of cortical actin in skeletal muscle demonstrates an essential role of the cytoskeleton in glucose transporter 4 translocation in insulin-sensitive tissues

21 January 2018

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The localization of myosin VI at the golgi complex and leading edge of fibroblasts and its phosphorylation and recruitment into membrane ruffles of A431 cells after growth factor stimulation

21 January 2018

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Pharmacology, physiology, and mechanisms of incretin hormone action

21 January 2018

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21 January 2018

PAKs in human disease

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Klotho endows hepatoma cells with resistance to anoikis via VEGFR2/PAK1 activation in hepatocellular carcinoma

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPENDO.00506.2013

P21-activated protein kinase 1 (Pak1) mediates the cross talk between insulin and β-catenin on proglucagon gene expression and its ablation affects glucose homeostasis in male C57BL/6 mice.

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPENDO.00506.2013

The role of the Wnt signaling pathway in incretin hormone production and function

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPENDO.00506.2013

Rac1 signalling towards GLUT4/glucose uptake in skeletal muscle.

21 January 2018

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https://api.crossref.org/works/10.1152%2FAJPENDO.00506.2013

Cdc42 deficiency causes ciliary abnormalities and cystic kidneys.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00506.2013

Biphasic regulation of myosin light chain phosphorylation by p21-activated kinase modulates intestinal smooth muscle contractility

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00506.2013

Regulation of glucose transport by ROCK1 differs from that of ROCK2 and is controlled by actin polymerization

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00506.2013

Cytoskeletal changes regulated by the PAK4 serine/threonine kinase are mediated by LIM kinase 1 and cofilin

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00506.2013

PAK5, a new brain-specific kinase, promotes neurite outgrowth in N1E-115 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00506.2013

An isoform-selective, small-molecule inhibitor targets the autoregulatory mechanism of p21-activated kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00506.2013

LKB1 suppresses p21-activated kinase-1 (PAK1) by phosphorylation of Thr109 in the p21-binding domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00506.2013

Cofilin activity downstream of Pak1 regulates cell protrusion efficiency by organizing lamellipodium and lamella actin networks

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00506.2013

Antagonistic cross-talk between Rac and Cdc42 GTPases regulates generation of reactive oxygen species

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00506.2013

Insulin resistance and cancer: the role of insulin and IGFs

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00506.2013

Hormonal, metabolic, and inflammatory profiles and endometrial cancer risk within the EPIC cohort--a factor analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00506.2013

Pak protein kinases and their role in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00506.2013

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00506.2013

Metabolic syndrome and risk of cancer: a systematic review and meta-analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00506.2013

UnPAKing the class differences among p21-activated kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00506.2013

Differential effects of PAK1-activating mutations reveal activity-dependent and -independent effects on cytoskeletal regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00506.2013

Cross-cascade activation of ERKs and ternary complex factors by Rho family proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00506.2013

Stimulation of NFkappa B activity by multiple signaling pathways requires PAK1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00506.2013

Selective amino acid restriction differentially affects the motility and directionality of DU145 and PC3 prostate cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00506.2013

Functional deficits in PAK5, PAK6 and PAK5/PAK6 knockout mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00506.2013

PAKing up to the endothelium.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00506.2013

Variant of transcription factor 7-like 2 (TCF7L2) gene confers risk of type 2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00506.2013

Rapid activation of FAK/mTOR/p70S6K/PAK1-signaling controls the early testosterone-induced actin reorganization in colon cancer cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00506.2013

Phosphorylation of beta-catenin by cyclic AMP-dependent protein kinase stabilizes beta-catenin through inhibition of its ubiquitination

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00506.2013

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00506.2013

Association between Pak1 expression and subcellular localization and tamoxifen resistance in breast cancer patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00506.2013

Inhibition of p21 activated kinase (PAK) reduces airway responsiveness in vivo and in vitro in murine and human airways

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00506.2013

Metabolic actions of Rho-kinase in periphery and brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00506.2013

p21-Activated kinases 1 and 3 control brain size through coordinating neuronal complexity and synaptic properties

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00506.2013

Identification and characterization of a novel inositol polyphosphate 5-phosphatase

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00506.2013

Regulation of insulin signaling and glucose transporter 4 (GLUT4) exocytosis by phosphatidylinositol 3,4,5-trisphosphate (PIP3) phosphatase, skeletal muscle, and kidney enriched inositol polyphosphate phosphatase (SKIP).

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00506.2013

Regulation of insulin signaling by the phosphatidylinositol 3,4,5-triphosphate phosphatase SKIP through the scaffolding function of Pak1

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00506.2013

SKIP negatively regulates insulin-induced GLUT4 translocation and membrane ruffle formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00506.2013

SAD: a presynaptic kinase associated with synaptic vesicles and the active zone cytomatrix that regulates neurotransmitter release

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00506.2013

Insulin resistance and cancer: epidemiological evidence

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00506.2013

The involvement of the wnt signaling pathway and TCF7L2 in diabetes mellitus: The current understanding, dispute, and perspective

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00506.2013

Muscle cells engage Rab8A and myosin Vb in insulin-dependent GLUT4 translocation

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00506.2013

P21-activated kinase 1: a new molecular marker for intravesical recurrence after transurethral resection of bladder cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00506.2013

p21-activated kinases: three more join the Pak.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00506.2013

Ceramide- and oxidant-induced insulin resistance involve loss of insulin-dependent Rac-activation and actin remodeling in muscle cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00506.2013

The role of p21-activated kinase in the initiation of atherosclerosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00506.2013

Mechanisms underlying proglucagon gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00506.2013

The WNT signalling pathway and diabetes mellitus

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00506.2013

Wnt and beyond Wnt: multiple mechanisms control the transcriptional property of beta-catenin

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00506.2013

The Wnt signaling pathway effector TCF7L2 and type 2 diabetes mellitus

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00506.2013

The association between metabolic syndrome and colorectal neoplasm: systemic review and meta-analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00506.2013

Role of the serine-threonine kinase PAK-1 in myxoma virus replication

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00506.2013

Signaling mechanisms of glucose-induced F-actin remodeling in pancreatic islet β cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00506.2013

A p21-activated kinase (PAK1) signaling cascade coordinately regulates F-actin remodeling and insulin granule exocytosis in pancreatic β cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00506.2013

A method to identify serine kinase substrates. Akt phosphorylates a novel adipocyte protein with a Rab GTPase-activating protein (GAP) domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00506.2013

Regulation of cardiac excitation and contraction by p21 activated kinase-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00506.2013

Role of p21-activated kinases in cardiovascular development and function

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00506.2013

Mouse models of PAK function

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00506.2013

Nonautonomous regulation of neuronal migration by insulin signaling, DAF-16/FOXO, and PAK-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00506.2013

PAK1 as a therapeutic target

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00506.2013

The protein kinase Pak3 positively regulates Raf-1 activity through phosphorylation of serine 338

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00506.2013

p21-activated kinase (PAK1) is phosphorylated and activated by 3-phosphoinositide-dependent kinase-1 (PDK1).

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00506.2013

Merlin, the Product of the Nf2 Tumor Suppressor Gene, Is an Inhibitor of the p21-Activated Kinase, Pak1

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00506.2013

Small G proteins in islet beta-cell function

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00506.2013

PAK signalling in neuronal physiology

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00506.2013

p21-activated kinases in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00506.2013

Nuclear factor of activated T cells c1 mediates p21-activated kinase 1 activation in the modulation of chemokine-induced human aortic smooth muscle cell F-actin stress fiber formation, migration, and proliferation and injury-induced vascular wall re

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00506.2013

AR and ER interaction with a p21-activated kinase (PAK6)

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00506.2013

Structure of PAK1 in an autoinhibited conformation reveals a multistage activation switch

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00506.2013

p21-activated kinase 1 interacts with and phosphorylates histone H3 in breast cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00506.2013

Novel regulation by Rac1 of glucose- and forskolin-induced insulin secretion in INS-1 beta-cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00506.2013

PAK as a therapeutic target in gastric cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00506.2013

Targeted disruption of the gene for the PAK5 kinase in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00506.2013

The closure of Pak1-dependent macropinosomes requires the phosphorylation of CtBP1/BARS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00506.2013

FRAX597, a Small Molecule Inhibitor of the p21-activated Kinases, Inhibits Tumorigenesis of Neurofibromatosis Type 2 (NF2)-associated Schwannomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00506.2013

The rho guanosine 5'-triphosphatase, cell division cycle 42, is required for insulin-induced actin remodeling and glucagon-like peptide-1 secretion in the intestinal endocrine L cell

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00506.2013

N-acetylglucosaminyltransferase V confers hepatoma cells with resistance to anoikis through EGFR/PAK1 activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00506.2013

Pak1 as a novel therapeutic target for antihypertrophic treatment in the heart

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00506.2013

Regulation of AChR clustering by Dishevelled interacting with MuSK and PAK1

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00506.2013

Rac1/PAK1 signaling promotes epithelial-mesenchymal transition of podocytes in vitro via triggering β-catenin transcriptional activity under high glucose conditions

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00506.2013

Expression of constitutively active alpha-PAK reveals effects of the kinase on actin and focal complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00506.2013

A brain serine/threonine protein kinase activated by Cdc42 and Rac1

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00506.2013

PAK kinases are directly coupled to the PIX family of nucleotide exchange factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00506.2013

Genomic alterations in blastic natural killer/extranodal natural killer-like T cell lymphoma with cutaneous involvement.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00506.2013

P21-activated kinase is required for mitotic progression and regulates Plk1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00506.2013

Estrogen regulation of Pak1 and FKHR pathways in breast cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00506.2013

Pak1 regulates multiple c-Kit mediated Ras-MAPK gain-in-function phenotypes in Nf1+/- mast cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00506.2013

Abnormal long-lasting synaptic plasticity and cognition in mice lacking the mental retardation gene Pak3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00506.2013

PAK signaling in oncogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00506.2013

Cdc42Hs, but not Rac1, inhibits serum-stimulated cell cycle progression at G1/S through a mechanism requiring p38/RK.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00506.2013

Targeted disruption of the Pak5 and Pak6 genes in mice leads to deficits in learning and locomotion

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00506.2013

Transcriptional activation of the proglucagon gene by lithium and beta-catenin in intestinal endocrine L cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00506.2013

Synapses of amphids defective (SAD-A) kinase promotes glucose-stimulated insulin secretion through activation of p21-activated kinase (PAK1) in pancreatic β-Cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00506.2013

The Pak1 kinase: an important regulator of neuronal morphology and function in the developing forebrain

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00506.2013

Role of RalA downstream of Rac1 in insulin-dependent glucose uptake in muscle cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00506.2013

Targeting p21-activated kinase 1 (PAK1) to induce apoptosis of tumor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00506.2013

p21-activated kinase 1: PAK'ed with potential

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00506.2013

The links between insulin resistance, diabetes, and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00506.2013

Group I p21-activated kinases: emerging roles in immune function and viral pathogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00506.2013

Phosphorylation of β-catenin at serine 663 regulates its transcriptional activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00506.2013

Dissecting activation of the PAK1 kinase at protrusions in living cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00506.2013

Role of the p21-activated kinases (PAKs) in influenza A virus replication

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00506.2013

Glucagon gene transcription is negatively regulated by insulin in a hamster islet cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00506.2013

Insulin regulation of the glucagon gene is mediated by an insulin-responsive DNA element

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00506.2013

Pak3 promotes cell cycle exit and differentiation of β-cells in the embryonic pancreas and is necessary to maintain glucose homeostasis in adult mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00506.2013

p21-Activated kinase (PAK) is required for Bone Morphogenetic Protein (BMP)-induced dendritogenesis in cortical neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00506.2013

p21-activated kinase 1 (PAK1) interacts with the Grb2 adapter protein to couple to growth factor signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00506.2013

Insulin-like growth factor-1 regulates endogenous RUNX2 activity in endothelial cells through a phosphatidylinositol 3-kinase/ERK-dependent and Akt-independent signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00506.2013

PAK4 Kinase Is Essential for Embryonic Viability and for Proper Neuronal Development

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00506.2013

MicroRNA-7, a homeobox D10 target, inhibits p21-activated kinase 1 and regulates its functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00506.2013

P21-activated kinase 1: convergence point in PDGF- and LPA-stimulated collagen matrix contraction by human fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00506.2013

HGF and IGF-1 synergize with SDF-1α in promoting migration of myeloma cells by cooperative activation of p21-activated kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00506.2013

Cytostatic p21 G protein-activated protein kinase gamma-PAK

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00506.2013

LAT-independent Erk activation via Bam32-PLC-γ1-Pak1 complexes: GTPase-independent Pak1 activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00506.2013

Putting Rac1 on the path to glucose uptake

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00506.2013

Inhibition of myosin light chain kinase by p21-activated kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00506.2013

p21-activated kinase 1 phosphorylates the death agonist bad and protects cells from apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00506.2013

p21-activated kinase 1 (Pak1) regulates cell motility in mammalian fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00506.2013

The Wnt signaling pathway effector TCF7L2 controls gut and brain proglucagon gene expression and glucose homeostasis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00506.2013

Pak6 protein kinase is a novel effector of an atypical Rho family GTPase Chp/RhoV

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00506.2013

Diabetes mellitus carries a risk of gastric cancer: a meta-analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00506.2013

Nuclear localization and chromatin targets of p21-activated kinase 1

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00506.2013

PAK1-mediated activation of ERK1/2 regulates lamellipodial dynamics

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00506.2013

Lithium inhibits glycogen synthase kinase-3 activity and mimics wingless signalling in intact cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00506.2013

Insulin-increased prolactin gene expression requires actin treadmilling: potential role for p21 activated kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00506.2013

A Pak1-PP2A-ERM signaling axis mediates F-actin rearrangement and degranulation in mast cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00506.2013

P-21-activated protein kinase-1 functions as a linker between insulin and Wnt signaling pathways in the intestine

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00506.2013

Rab8A and Rab13 are activated by insulin and regulate GLUT4 translocation in muscle cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00506.2013

Rac1 signaling is required for insulin-stimulated glucose uptake and is dysregulated in insulin-resistant murine and human skeletal muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00506.2013

Rac1 is a novel regulator of contraction-stimulated glucose uptake in skeletal muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00506.2013

Akt and Rac1 signaling are jointly required for insulin-stimulated glucose uptake in skeletal muscle and downregulated in insulin resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00506.2013

Ablation of p21-activated kinase-1 in mice promotes isoproterenol-induced cardiac hypertrophy in association with activation of Erk1/2 and inhibition of protein phosphatase 2A

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00506.2013

CRIPak, a novel endogenous Pak1 inhibitor

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00506.2013

Kinase-deficient Pak1 mutants inhibit Ras transformation of Rat-1 fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00506.2013

Wrch-1, a novel member of the Rho gene family that is regulated by Wnt-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00506.2013

Phosphorylation of beta-catenin by cyclic AMP-dependent protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00506.2013

A vertebrate-specific Chp-PAK-PIX pathway maintains E-cadherin at adherens junctions during zebrafish epiboly

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00506.2013

Identification and Molecular Cloning of a p21cdc42/rac1-activated Serine/Threonine Kinase That Is Rapidly Activated by Thrombin in Platelets

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00506.2013

The Rab GTPase-activating protein AS160 integrates Akt, protein kinase C, and AMP-activated protein kinase signals regulating GLUT4 traffic.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00506.2013

The kinase-inhibitory domain of p21-activated kinase 1 (PAK1) inhibits cell cycle progression independent of PAK1 kinase activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00506.2013

A key role for Pak4 in proliferation and differentiation of neural progenitor cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00506.2013

Phosphorylation of Raf-1 by p21-activated kinase 1 and Src regulates Raf-1 autoinhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00506.2013

Insulin activates a p21-activated kinase in muscle cells via phosphatidylinositol 3-kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00506.2013

Phosphatidylinositol 3-kinase and the actin network are not required for the stimulation of glucose transport caused by mitochondrial uncoupling: comparison with insulin action

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00506.2013

Activation of the small GTPase Rac1 by a specific guanine-nucleotide-exchange factor suffices to induce glucose uptake into skeletal-muscle cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00506.2013

Crucial role of the small GTPase Rac1 in insulin-stimulated translocation of glucose transporter 4 to the mouse skeletal muscle sarcolemma

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00506.2013

Dynein light chain 1, a p21-activated kinase 1-interacting substrate, promotes cancerous phenotypes

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00506.2013

An emerging role for p21-activated kinases (Paks) in viral infections

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00506.2013

Different molecular mechanisms for Rho family GTPase-dependent, Ca2+-independent contraction of smooth muscle.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00506.2013

Dynamics of Insulin Release and Microtubular-Microfilamentous System. I. EFFECT OF CYTOCHALASIN B

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00506.2013

Fasting proinsulin levels are significantly associated with 20 year cancer mortality rates. The Hoorn Study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00506.2013

A role for Gab1/SHP2 in thrombin activation of PAK1: gene transfer of kinase-dead PAK1 inhibits injury-induced restenosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00506.2013

p21-activated kinase 1 (PAK1) can promote ERK activation in a kinase-independent manner

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00506.2013

Inhibition or ablation of p21-activated kinase (PAK1) disrupts glucose homeostatic mechanisms in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00506.2013

Glucose-stimulated Cdc42 signaling is essential for the second phase of insulin secretion

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00506.2013

Phosphoinositide-dependent kinase 1 and p21-activated protein kinase mediate reactive oxygen species-dependent regulation of platelet-derived growth factor-induced smooth muscle cell migration

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00506.2013

A twenty-first century cancer epidemic caused by obesity: the involvement of insulin, diabetes, and insulin-like growth factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00506.2013

Inhibition of Contraction and Myosin Light Chain Phosphorylation in Guinea‐Pig Smooth Muscle by p21‐Activated Kinase 1

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00506.2013

Hyperglycemia, insulin resistance, impaired pancreatic β-cell function, and risk of pancreatic cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00506.2013

Regulation of the p21-activated kinase (PAK) by a human Gbeta -like WD-repeat protein, hPIP1

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00506.2013

A Nck-Pak1 signaling module is required for T-cell receptor-mediated activation of NFAT, but not of JNK

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00506.2013

Androgen receptor specifically interacts with a novel p21-activated kinase, PAK6

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00506.2013

Activation of Rac1-PI3K/Akt is required for epidermal growth factor-induced PAK1 activation and cell migration in MDA-MB-231 breast cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00506.2013

TCF-4 mediates cell type-specific regulation of proglucagon gene expression by beta-catenin and glycogen synthase kinase-3beta

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00506.2013

Cross talk between the insulin and Wnt signaling pathways: evidence from intestinal endocrine L cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00506.2013

ERK activation of p21 activated kinase-1 (Pak1) is critical for medulloblastoma cell migration

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00506.2013

Identification of a central phosphorylation site in p21-activated kinase regulating autoinhibition and kinase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00506.2013

A GIT1/PIX/Rac/PAK signaling module regulates spine morphogenesis and synapse formation through MLC

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00506.2013

The GIT-associated kinase PAK targets to the centrosome and regulates Aurora-A.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00506.2013

Tumor necrosis factor-alpha induced expression of matrix metalloproteinase-9 through p21-activated kinase-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00506.2013

A Rac1/PAK1 cascade controls β-catenin activation in colon cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00506.2013

6beta4 integrin activates Rac-dependent p21-activated kinase 1 to drive NF- B-dependent resistance to apoptosis in 3D mammary acini

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00506.2013

Regulatable Expression of p21-activated Kinase-1 Promotes Anchorage-independent Growth and Abnormal Organization of Mitotic Spindles in Human Epithelial Breast Cancer Cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00506.2013

The Phosphorylation Site for Ste20p-like Protein Kinases Is Essential for the Function of Myosin-I in Yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPENDO.00506.2013

10.1152/AJPENDO.00506.2013

21 January 2018

Identifiers

DOI

1 reference

30 August 2017

1 reference