(Q90239197)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32160513%20AND%20SRC:MED&resulttype=core&format=json

12 April 2020

review article

1 reference

title

Autophagy-Dependent Ferroptosis: Machinery and Regulation (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32160513%20AND%20SRC:MED&resulttype=core&format=json

12 April 2020

0 references

0 references

1 reference

3

Guido Kroemer

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32160513%20AND%20SRC:MED&resulttype=core&format=json

12 April 2020

author name string

Jiao Liu

1

1 reference

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12 April 2020

Feimei Kuang

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32160513%20AND%20SRC:MED&resulttype=core&format=json

12 April 2020

Daniel J Klionsky

4

1 reference

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12 April 2020

Rui Kang

5

1 reference

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12 April 2020

Daolin Tang

6

1 reference

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12 April 2020

publication date

3 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32160513%20AND%20SRC:MED&resulttype=core&format=json

12 April 2020

published in

Cell chemical biology

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32160513%20AND%20SRC:MED&resulttype=core&format=json

Protection against fatal Sindbis virus encephalitis by beclin, a novel Bcl-2-interacting protein

12 April 2020

volume

27

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issue

4

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page(s)

420-435

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cites work

1 reference

12 December 2020

Induction of autophagy and inhibition of tumorigenesis by beclin 1

1 reference

12 December 2020

LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing

1 reference

12 December 2020

Autophagy as a regulated pathway of cellular degradation

1 reference

12 December 2020

Embryonic fibroblasts from Gpx4+/- mice: a novel model for studying the role of membrane peroxidation in biological processes

1 reference

12 December 2020

Transgenic mice overexpressing glutathione peroxidase 4 are protected against oxidative stress-induced apoptosis

1 reference

12 December 2020

Bcl-2 antiapoptotic proteins inhibit Beclin 1-dependent autophagy

1 reference

12 December 2020

Glutathione peroxidase 4 protects cortical neurons from oxidative injury and amyloid toxicity.

1 reference

12 December 2020

Autophagic and tumour suppressor activity of a novel Beclin1-binding protein UVRAG

1 reference

12 December 2020

Crystal structure of the Bcl-XL-Beclin 1 peptide complex: Beclin 1 is a novel BH3-only protein

1 reference

12 December 2020

Reactive oxygen species are essential for autophagy and specifically regulate the activity of Atg4

1 reference

12 December 2020

Proteomic Analysis of Membrane-Associated Proteins from Rat Liver Autophagosomes

1 reference

12 December 2020

RAS-RAF-MEK-dependent oxidative cell death involving voltage-dependent anion channels

1 reference

12 December 2020

p62/SQSTM1 binds directly to Atg8/LC3 to facilitate degradation of ubiquitinated protein aggregates by autophagy

1 reference

12 December 2020

How to interpret LC3 immunoblotting

1 reference

12 December 2020

Pex14 is the sole component of the peroxisomal translocon that is required for pexophagy

1 reference

12 December 2020

The Atg12-Atg5 conjugate has a novel E3-like activity for protein lipidation in autophagy

1 reference

12 December 2020

Synthetic lethal screening identifies compounds activating iron-dependent, nonapoptotic cell death in oncogenic-RAS-harboring cancer cells

1 reference

12 December 2020

Essential role for Nix in autophagic maturation of erythroid cells

1 reference

12 December 2020

Glutathione peroxidase 4 senses and translates oxidative stress into 12/15-lipoxygenase dependent- and AIF-mediated cell death

1 reference

12 December 2020

Autophagic cell death: the story of a misnomer

1 reference

12 December 2020

Loss of PINK1 function promotes mitophagy through effects on oxidative stress and mitochondrial fission

1 reference

12 December 2020

A novel, human Atg13 binding protein, Atg101, interacts with ULK1 and is essential for macroautophagy

1 reference

12 December 2020

The inositol 1,4,5-trisphosphate receptor regulates autophagy through its interaction with Beclin 1.

1 reference

12 December 2020

Autophagy regulates lipid metabolism

1 reference

12 December 2020

The Parkinson-associated protein PINK1 interacts with Beclin1 and promotes autophagy

1 reference

12 December 2020

PINK1/Parkin-mediated mitophagy is dependent on VDAC1 and p62/SQSTM1

1 reference

12 December 2020

HMGB1 release and redox regulates autophagy and apoptosis in cancer cells

1 reference

12 December 2020

Interaction of Beclin 1 with survivin regulates sensitivity of human glioma cells to TRAIL-induced apoptosis

1 reference

12 December 2020

Regulation of the autophagy protein LC3 by phosphorylation

1 reference

12 December 2020

Eaten alive: a history of macroautophagy

1 reference

12 December 2020

The origin of the autophagosomal membrane

1 reference

12 December 2020

Endogenous HMGB1 regulates autophagy

1 reference

12 December 2020

Rubicon and PLEKHM1 negatively regulate the endocytic/autophagic pathway via a novel Rab7-binding domain

1 reference

12 December 2020

Autophagy and the integrated stress response

1 reference

12 December 2020

Zymophagy, a novel selective autophagy pathway mediated by VMP1-USP9x-p62, prevents pancreatic cell death

1 reference

12 December 2020

AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1

1 reference

12 December 2020

The Beclin 1 network regulates autophagy and apoptosis

1 reference

12 December 2020

The requirement of uncoordinated 51-like kinase 1 (ULK1) and ULK2 in the regulation of autophagy

1 reference

12 December 2020

Autophagosome targeting and membrane curvature sensing by Barkor/Atg14(L).

1 reference

12 December 2020

High-mobility group box 1 is essential for mitochondrial quality control

1 reference

12 December 2020

Beneficial role of Nrf2 in regulating NADPH generation and consumption

1 reference

12 December 2020

Image-based genome-wide siRNA screen identifies selective autophagy factors

1 reference

12 December 2020

Autophagic removal of micronuclei

1 reference

12 December 2020

Atg4 recycles inappropriately lipidated Atg8 to promote autophagosome biogenesis

1 reference

12 December 2020

Mitochondrial outer-membrane protein FUNDC1 mediates hypoxia-induced mitophagy in mammalian cells

1 reference

12 December 2020

GSK3-TIP60-ULK1 signaling pathway links growth factor deprivation to autophagy

1 reference

12 December 2020

Regulation of lipid stores and metabolism by lipophagy

1 reference

12 December 2020

Ferroptosis: an iron-dependent form of nonapoptotic cell death

1 reference

12 December 2020

Glutathione peroxidase 4 has a major role in protecting mitochondria from oxidative damage and maintaining oxidative phosphorylation complexes in gut epithelial cells

1 reference

12 December 2020

Autophagy as a stress-response and quality-control mechanism: implications for cell injury and human disease

1 reference

12 December 2020

NBR1 acts as an autophagy receptor for peroxisomes

1 reference

12 December 2020

The VMP1-Beclin 1 interaction regulates autophagy induction

1 reference

12 December 2020

Regulation of mitophagy by the Gp78 E3 ubiquitin ligase

1 reference

12 December 2020

mTOR inhibits autophagy by controlling ULK1 ubiquitylation, self-association and function through AMBRA1 and TRAF6.

1 reference

12 December 2020

ULK1 induces autophagy by phosphorylating Beclin-1 and activating VPS34 lipid kinase.

1 reference

12 December 2020

Eukaryotic stress granules are cleared by autophagy and Cdc48/VCP function

1 reference

12 December 2020

Spatiotemporally controlled induction of autophagy-mediated lysosome turnover

1 reference

12 December 2020

Autophagy sequesters damaged lysosomes to control lysosomal biogenesis and kidney injury

1 reference

12 December 2020

EGFR-mediated Beclin 1 phosphorylation in autophagy suppression, tumor progression, and tumor chemoresistance

1 reference

12 December 2020

Cardiolipin externalization to the outer mitochondrial membrane acts as an elimination signal for mitophagy in neuronal cells

1 reference

12 December 2020

Myocardial glycophagy - a specific glycogen handling response to metabolic stress is accentuated in the female heart.

1 reference

12 December 2020

Regulation of ferroptotic cancer cell death by GPX4

1 reference

12 December 2020

Quantitative proteomics identifies NCOA4 as the cargo receptor mediating ferritinophagy

1 reference

12 December 2020

Pharmacological inhibition of cystine-glutamate exchange induces endoplasmic reticulum stress and ferroptosis

1 reference

12 December 2020

MUL1 acts in parallel to the PINK1/parkin pathway in regulating mitofusin and compensates for loss of PINK1/parkin

1 reference

12 December 2020

The membrane peroxin PEX3 induces peroxisome-ubiquitination-linked pexophagy

1 reference

12 December 2020

Optineurin is an autophagy receptor for damaged mitochondria in parkin-mediated mitophagy that is disrupted by an ALS-linked mutation

1 reference

12 December 2020

Parkin-independent mitophagy requires Drp1 and maintains the integrity of mammalian heart and brain

1 reference

12 December 2020

Inactivation of the ferroptosis regulator Gpx4 triggers acute renal failure in mice

1 reference

12 December 2020

Posttranslational modification of autophagy-related proteins in macroautophagy

1 reference

12 December 2020

The mitochondrial protein BNIP3L is the substrate of PARK2 and mediates mitophagy in PINK1/PARK2 pathway

1 reference

12 December 2020

HSPB1 as a novel regulator of ferroptotic cancer cell death

1 reference

12 December 2020

An RNautophagy/DNautophagy receptor, LAMP2C, possesses an arginine-rich motif that mediates RNA/DNA-binding

1 reference

12 December 2020

Ferroptosis as a p53-mediated activity during tumour suppression

1 reference

12 December 2020

T cell lipid peroxidation induces ferroptosis and prevents immunity to infection.

1 reference

12 December 2020

Deubiquitinating enzymes regulate PARK2-mediated mitophagy

1 reference

12 December 2020

Human Haploid Cell Genetics Reveals Roles for Lipid Metabolism Genes in Nonapoptotic Cell Death

1 reference

12 December 2020

Autophagic Degradation of the 26S Proteasome Is Mediated by the Dual ATG8/Ubiquitin Receptor RPN10 in Arabidopsis

1 reference

12 December 2020

Regulation of endoplasmic reticulum turnover by selective autophagy

1 reference

12 December 2020

Sensitive detection of lysosomal membrane permeabilization by lysosomal galectin puncta assay.

1 reference

12 December 2020

Bcl-2-like protein 13 is a mammalian Atg32 homologue that mediates mitophagy and mitochondrial fragmentation

1 reference

12 December 2020

Schwann cell autophagy, myelinophagy, initiates myelin clearance from injured nerves.

1 reference

12 December 2020

The 5-Lipoxygenase Inhibitor Zileuton Confers Neuroprotection against Glutamate Oxidative Damage by Inhibiting Ferroptosis

1 reference

12 December 2020

BNIP3- and BNIP3L-Mediated Mitophagy Promotes the Generation of Natural Killer Cell Memory.

1 reference

12 December 2020

The ubiquitin kinase PINK1 recruits autophagy receptors to induce mitophagy

1 reference

12 December 2020

ATM functions at the peroxisome to induce pexophagy in response to ROS.

1 reference

12 December 2020

The PINK1-PARKIN Mitochondrial Ubiquitylation Pathway Drives a Program of OPTN/NDP52 Recruitment and TBK1 Activation to Promote Mitophagy

1 reference

12 December 2020

Activation of the p62-Keap1-NRF2 pathway protects against ferroptosis in hepatocellular carcinoma cells

1 reference

12 December 2020

Ferritinophagy via NCOA4 is required for erythropoiesis and is regulated by iron dependent HERC2-mediated proteolysis.

1 reference

12 December 2020

Glutathione peroxidase 4 prevents necroptosis in mouse erythroid precursors

1 reference

12 December 2020

Autophagy mediates degradation of nuclear lamina

1 reference

12 December 2020

Activation of ULK Kinase and Autophagy by GABARAP Trafficking from the Centrosome Is Regulated by WAC and GM130.

1 reference

12 December 2020

Regulators of Iron Homeostasis: New Players in Metabolism, Cell Death, and Disease

1 reference

12 December 2020

An essential role for functional lysosomes in ferroptosis of cancer cells.

1 reference

12 December 2020

Ferroptosis: process and function

1 reference

12 December 2020

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

1 reference

12 December 2020

Global survey of cell death mechanisms reveals metabolic regulation of ferroptosis.

1 reference

12 December 2020

Autophagy promotes ferroptosis by degradation of ferritin

1 reference

12 December 2020

Dynamic recruitment and activation of ALS-associated TBK1 with its target optineurin are required for efficient mitophagy

1 reference

12 December 2020

The PINK1, synphilin-1 and SIAH-1 complex constitutes a novel mitophagy pathway.

1 reference

12 December 2020

Dihydroartemisinin (DHA) induces ferroptosis and causes cell cycle arrest in head and neck carcinoma cells

1 reference

12 December 2020

Peroxidation of polyunsaturated fatty acids by lipoxygenases drives ferroptosis.

1 reference

12 December 2020

CISD1 inhibits ferroptosis by protection against mitochondrial lipid peroxidation.

1 reference

12 December 2020

Ferroptosis is an autophagic cell death process

1 reference

12 December 2020

Identification of ACSL4 as a biomarker and contributor of ferroptosis

1 reference

12 December 2020

PEX2 is the E3 ubiquitin ligase required for pexophagy during starvation

1 reference

12 December 2020

LC3/GABARAP family proteins: autophagy-(un)related functions

1 reference

12 December 2020

Translocon component Sec62 acts in endoplasmic reticulum turnover during stress recovery.

1 reference

12 December 2020

A novel PINK1- and PARK2-dependent protective neuroimmune pathway in lethal sepsis

1 reference

12 December 2020

Peroxisomal protein PEX13 functions in selective autophagy.

1 reference

12 December 2020

Oxidized arachidonic and adrenic PEs navigate cells to ferroptosis

1 reference

12 December 2020

ACSL4 dictates ferroptosis sensitivity by shaping cellular lipid composition

1 reference

12 December 2020

Regulation of mATG9 trafficking by Src- and ULK1-mediated phosphorylation in basal and starvation-induced autophagy

1 reference

12 December 2020

Prohibitin 2 Is an Inner Mitochondrial Membrane Mitophagy Receptor.

1 reference

12 December 2020

The Protective Role of Mitochondrial Ferritin on Erastin-Induced Ferroptosis

1 reference

12 December 2020

HSPA5 Regulates Ferroptotic Cell Death in Cancer Cells

1 reference

12 December 2020

New insights into autophagosome-lysosome fusion

1 reference

12 December 2020

FKBP8 recruits LC3A to mediate Parkin-independent mitophagy.

1 reference

12 December 2020

Inhibition of iron overload-induced apoptosis and necrosis of bone marrow mesenchymal stem cells by melatonin.

1 reference

12 December 2020

Necroptosis and ferroptosis are alternative cell death pathways that operate in acute kidney failure

1 reference

12 December 2020

Full length RTN3 regulates turnover of tubular endoplasmic reticulum via selective autophagy

1 reference

12 December 2020

Proteomic Analysis of the Human Tankyrase Protein Interaction Network Reveals Its Role in Pexophagy.

1 reference

12 December 2020

Ubiquitination of exposed glycoproteins by SCFFBXO27 directs damaged lysosomes for autophagy.

1 reference

12 December 2020

The Tumor Suppressor p53 Limits Ferroptosis by Blocking DPP4 Activity.

1 reference

12 December 2020

Lipoxygenase-mediated generation of lipid peroxides enhances ferroptosis induced by erastin and RSL3.

1 reference

12 December 2020

Monitoring and Measuring Autophagy

1 reference

12 December 2020

Autophagy-Independent Lysosomal Targeting Regulated by ULK1/2-FIP200 and ATG9.

1 reference

12 December 2020

Role of PEX5 ubiquitination in maintaining peroxisome dynamics and homeostasis.

1 reference

12 December 2020

NRF2 Is a Major Target of ARF in p53-Independent Tumor Suppression

1 reference

12 December 2020

Ferroptosis: A Regulated Cell Death Nexus Linking Metabolism, Redox Biology, and Disease

1 reference

12 December 2020

Autophagy and Ferroptosis - What's the Connection?

1 reference

12 December 2020

PEBP1 Wardens Ferroptosis by Enabling Lipoxygenase Generation of Lipid Death Signals.

1 reference

12 December 2020

Systematic analysis of ribophagy in human cells reveals bystander flux during selective autophagy

1 reference

12 December 2020

ER homeostasis and autophagy

1 reference

12 December 2020

Detection and Clearance of Damaged Lysosomes by the Endo-Lysosomal Damage Response and Lysophagy

1 reference

12 December 2020

CCPG1 Is a Non-canonical Autophagy Cargo Receptor Essential for ER-Phagy and Pancreatic ER Proteostasis

1 reference

12 December 2020

ULK1 phosphorylates Ser30 of BECN1 in association with ATG14 to stimulate autophagy induction.

1 reference

12 December 2020

Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018.

1 reference

12 December 2020

Molecular crosstalk between ferroptosis and apoptosis: emerging role of ER stress-induced p53-independent PUMA expression.

1 reference

12 December 2020

Cargo recognition and degradation by selective autophagy.

1 reference

12 December 2020

Protein biosynthesis, a target of sorafenib, interferes with the unfolded protein response (UPR) and ferroptosis in hepatocellular carcinoma cells.

1 reference

12 December 2020

Ferroptosis-induced Endoplasmic Reticulum Stress: Crosstalk Between Ferroptosis and Apoptosis.

1 reference

12 December 2020

Mechanism and medical implications of mammalian autophagy

1 reference

12 December 2020

The p53 Tumor Suppressor in the Control of Metabolism and Ferroptosis.

1 reference

12 December 2020

NUFIP1 is a ribosome receptor for starvation-induced ribophagy

1 reference

12 December 2020

The tumor suppressor protein p53 and the ferroptosis network.

1 reference

12 December 2020

The Role of Reactive Oxygen Species and Ferroptosis in Heme-Mediated Activation of Human Platelets

1 reference

12 December 2020

Lipid Peroxidation Drives Gasdermin D-Mediated Pyroptosis in Lethal Polymicrobial Sepsis

1 reference

12 December 2020

Knockdown of ferroportin accelerates erastin-induced ferroptosis in neuroblastoma cells

1 reference

12 December 2020

Ferroptosis is a lysosomal cell death process

1 reference

12 December 2020

AMPK-Mediated BECN1 Phosphorylation Promotes Ferroptosis by Directly Blocking System Xc- Activity

1 reference

12 December 2020

Upregulation and activation of p53 by erastin‑induced reactive oxygen species contribute to cytotoxic and cytostatic effects in A549 lung cancer cells

1 reference

12 December 2020

Activation of ferritinophagy is required for the RNA-binding protein ELAVL1/HuR to regulate ferroptosis in hepatic stellate cells

1 reference

12 December 2020

PINK1 and PARK2 Suppress Pancreatic Tumorigenesis through Control of Mitochondrial Iron-Mediated Immunometabolism

1 reference

12 December 2020

Vitamin E hydroquinone is an endogenous regulator of ferroptosis via redox control of 15-lipoxygenase

1 reference

12 December 2020

1 reference

12 December 2020

BECN1 is a new driver of ferroptosis

1 reference

12 December 2020

Autophagy-dependent cell death - where, how and why a cell eats itself to death

1 reference

12 December 2020

Tom20 senses iron-activated ROS signaling to promote melanoma cell pyroptosis

1 reference

12 December 2020

Nrf2 inhibition reverses resistance to GPX4 inhibitor-induced ferroptosis in head and neck cancer

1 reference

12 December 2020

Selective Autophagy and Xenophagy in Infection and Disease

1 reference

12 December 2020

Lipid storage and lipophagy regulates ferroptosis

1 reference

12 December 2020

Artesunate alleviates liver fibrosis by regulating ferroptosis signaling pathway

1 reference

12 December 2020

DHA inhibits proliferation and induces ferroptosis of leukemia cells through autophagy dependent degradation of ferritin

1 reference

12 December 2020

Autophagy-dependent cell death

1 reference

12 December 2020

Role of Mitochondria in Ferroptosis

1 reference

12 December 2020

RAB7A phosphorylation by TBK1 promotes mitophagy via the PINK-PARKIN pathway

1 reference

12 December 2020

Biological Functions of Autophagy Genes: A Disease Perspective

1 reference

12 December 2020

Nucleophagy: from homeostasis to disease

1 reference

12 December 2020

The release and activity of HMGB1 in ferroptosis

1 reference

12 December 2020

Chaperone-mediated autophagy is involved in the execution of ferroptosis

1 reference

12 December 2020

Nuclear accumulation of UBC9 contributes to SUMOylation of lamin A/C and nucleophagy in response to DNA damage

1 reference

12 December 2020

ATL3 Is a Tubular ER-Phagy Receptor for GABARAP-Mediated Selective Autophagy

1 reference

12 December 2020

Ferroptosis is a type of autophagy-dependent cell death

1 reference

12 December 2020

The molecular machinery of regulated cell death

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12 December 2020

A GPX4-dependent cancer cell state underlies the clear-cell morphology and confers sensitivity to ferroptosis

1 reference

12 December 2020

NIPSNAP1 and NIPSNAP2 Act as "Eat Me" Signals for Mitophagy

1 reference

12 December 2020

Intrinsically Disordered Protein TEX264 Mediates ER-phagy

1 reference

12 December 2020

HMGB1 regulates erastin-induced ferroptosis via RAS-JNK/p38 signaling in HL-60/NRAS cells

1 reference

12 December 2020

A COPII subunit acts with an autophagy receptor to target endoplasmic reticulum for degradation

1 reference

12 December 2020

Selective Autophagy: ATG8 Family Proteins, LIR Motifs and Cargo Receptors

1 reference

12 December 2020

Intercellular interaction dictates cancer cell ferroptosis via NF2-YAP signalling

1 reference

12 December 2020

Recruitment and Activation of the ULK1/Atg1 Kinase Complex in Selective Autophagy

1 reference

12 December 2020

Clockophagy is a novel selective autophagy process favoring ferroptosis

1 reference

12 December 2020

The ubiquitin-conjugating enzyme UBE2QL1 coordinates lysophagy in response to endolysosomal damage

1 reference

12 December 2020

Autophagic degradation of the circadian clock regulator promotes ferroptosis

1 reference

12 December 2020

The Hippo Pathway Effector TAZ Regulates Ferroptosis in Renal Cell Carcinoma

1 reference

12 December 2020

The ubiquitin E2 enzyme UBE2QL1 mediates lysophagy

1 reference

12 December 2020

FSP1 is a glutathione-independent ferroptosis suppressor

1 reference

12 December 2020

The CoQ oxidoreductase FSP1 acts parallel to GPX4 to inhibit ferroptosis

1 reference

12 December 2020

ESCRT-III-dependent membrane repair blocks ferroptosis

1 reference

12 December 2020

Autophagy-dependent ferroptosis drives tumor-associated macrophage polarization via release and uptake of oncogenic KRAS protein

1 reference

12 December 2020

AIFM2 blocks ferroptosis independent of ubiquinol metabolism

1 reference

12 December 2020