(Q22299231)

English

Preadministration of High-Dose Salicylates, Suppressors of NF- B Activation, May Increase the Chemosensitivity of Many Cancers: An Example of Proapoptotic Signal Modulation Therapy

scientific article

Preadministration of high-dose salicylates, suppressors of NF-kappaB activation, may increase the chemosensitivity of many cancers: an example of proapoptotic signal modulation therapy

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Europe PubMed Central

Preadministration of High-Dose Salicylates, Suppressors of NF- B Activation, May Increase the Chemosensitivity of Many Cancers: An Example of Proapoptotic Signal Modulation Therapy (English)

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apoptotic process

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author name string

M. F. McCarty

1

author given names

Mark F

author last names

McCarty

1 reference

30 March 2023

Keith I Block

author given names

Keith I

author last names

Block

2

1 reference

30 March 2023

language of work or name

0 references

publication date

1 September 2006

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Integrative Cancer Therapies

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5

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3

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252-268

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Evidence for involvement of NF-kappaB in the transcriptional control of COX-2 gene expression by IL-1beta

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21 January 2018

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21 January 2018

Inhibition of NF-kappaB sensitizes non-small cell lung cancer cells to chemotherapy-induced apoptosis

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21 January 2018

Inhibition of NF-kappaB sensitizes human pancreatic carcinoma cells to apoptosis induced by etoposide (VP16) or doxorubicin

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21 January 2018

NF-kappa B-mediated chemoresistance in breast cancer cells

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NF-kappa B activation in human breast cancer specimens and its role in cell proliferation and apoptosis

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NF-kappa B activates prostate-specific antigen expression and is upregulated in androgen-independent prostate cancer

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Induction of human MDR1 gene expression by 2-acetylaminofluorene is mediated by effectors of the phosphoinositide 3-kinase pathway that activate NF-kappaB signaling

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NF-kappaB transcription factor induces drug resistance through MDR1 expression in cancer cells

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NF-kappa B signaling pathway as a target for human tumor radiosensitization

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21 January 2018

Nuclear factor-kappaB inhibitors as sensitizers to anticancer drugs

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21 January 2018

Nuclear factor-κB as a predictor of treatment response in breast cancer

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IKKalpha, IKKbeta, and NEMO/IKKgamma are each required for the NF-kappa B-mediated inflammatory response program.

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21 January 2018

Distinct roles of the Ikappa B kinase alpha and beta subunits in liberating nuclear factor kappa B (NF-kappa B) from Ikappa B and in phosphorylating the p65 subunit of NF-kappa B.

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21 January 2018

NF-kappaB-inducing kinase activates IKK-alpha by phosphorylation of Ser-176

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21 January 2018

MEKK1 activates both IkappaB kinase alpha and IkappaB kinase beta

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The antiapoptotic effect of fibroblast growth factor-2 is mediated through nuclear factor-kappaB activation induced via interaction between Akt and IkappaB kinase-beta in breast cancer cells.

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HER-2/neu blocks tumor necrosis factor-induced apoptosis via the Akt/NF-kappaB pathway

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Roles of Akt/PKB and IKK complex in constitutive induction of NF-kappaB in hepatocellular carcinomas of transforming growth factor alpha/c-myc transgenic mice.

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Activation of NF-kappaB and upregulation of intracellular anti-apoptotic proteins via the IGF-1/Akt signaling in human multiple myeloma cells: therapeutic implications

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21 January 2018

Inactivation of NF-kappaB by genistein is mediated via Akt signaling pathway in breast cancer cells

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21 January 2018

A sustained activation of PI3K/NF-kappaB pathway is critical for the survival of chronic lymphocytic leukemia B cells.

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21 January 2018

Role of NF-kappaB signaling in hepatocyte growth factor/scatter factor-mediated cell protection

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21 January 2018

The anti-inflammatory natural product parthenolide from the medicinal herb Feverfew directly binds to and inhibits IkappaB kinase

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21 January 2018

The anti-inflammatory agents aspirin and salicylate inhibit the activity of I(kappa)B kinase-beta

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21 January 2018

Sulindac inhibits activation of the NF-kappaB pathway

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The sesquiterpene lactone parthenolide in combination with docetaxel reduces metastasis and improves survival in a xenograft model of breast cancer.

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Mechanism by which high-dose aspirin improves glucose metabolism in type 2 diabetes

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Prevention of fat-induced insulin resistance by salicylate

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Serine phosphorylation of insulin receptor substrate 1 by inhibitor kappa B kinase complex.

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Salicylates inhibit NF-kappaB activation and enhance TNF-alpha-induced apoptosis in human pancreatic cancer cells

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21 January 2018

The contribution of NF-kappa B activity to spontaneous proliferation and resistance to apoptosis in human T-cell leukemia virus type 1 Tax-induced tumors

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21 January 2018

Activation of NF-kappaB is required for PDGF-B chain to transform NIH3T3 cells

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21 January 2018

Aspirin and NS-398 inhibit hepatocyte growth factor-induced invasiveness of human hepatoma cells

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21 January 2018

Aspirin inhibits TNFalpha- and IL-1-induced NF-kappaB activation and sensitizes HeLa cells to apoptosis

1 reference

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21 January 2018

Nuclear factor kappa B activation is a potential target for preventing pancreatic carcinoma by aspirin

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21 January 2018

Contrasting effects of aspirin on prostate cancer cells: suppression of proliferation and induction of drug resistance .

1 reference

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21 January 2018

Evidence for colorectal cancer cell specificity of aspirin effects on NF kappa B signalling and apoptosis

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21 January 2018

Aspirin-induced nuclear translocation of NFkappaB and apoptosis in colorectal cancer is independent of p53 status and DNA mismatch repair proficiency

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The IKK NF-kappa B system: a treasure trove for drug development

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Role of COX-2 inhibitors in cancer therapy

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21 January 2018

IKKbeta/NF-kappaB activation causes severe muscle wasting in mice

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21 January 2018

NF-kappaB mediates proteolysis-inducing factor induced protein degradation and expression of the ubiquitin-proteasome system in skeletal muscle

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Prevention of cancer cachexia by a novel nuclear factor {kappa}B inhibitor in prostate cancer.

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Parthenolide and sulindac cooperate to mediate growth suppression and inhibit the nuclear factor-kappa B pathway in pancreatic carcinoma cells.

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Role of p53 and NF-kappaB in epigallocatechin-3-gallate-induced apoptosis of LNCaP cells

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Effect of cis-resveratrol on genes involved in nuclear factor kappa B signaling

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PPAR-gamma activation inhibits angiogenesis by blocking ELR+CXC chemokine production in non-small cell lung cancer

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Apoptosis induced by activation of peroxisome-proliferator activated receptor-gamma is associated with Bcl-2 and NF-kappaB in human colon cancer

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PI 3-kinase, Akt and cell survival

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Oxygen sensing and oxidant/redox-related pathways

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21 January 2018

Selenium: a key element that controls NF-kappa B activation and I kappa B alpha half life.

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Redox signaling of NF-kappaB by membrane NAD(P)H oxidases in normal and malignant cells

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Overexpression of a novel superoxide-producing enzyme, NADPH oxidase 1, in adenoma and well differentiated adenocarcinoma of the human colon

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21 January 2018

Alpha-lipoic acid inhibits TNF-alpha-induced NF-kappaB activation and adhesion molecule expression in human aortic endothelial cells

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Radiotherapy and antiangiogenic TM in lung cancer

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21 January 2018

STAT proteins as novel targets for cancer drug discovery

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21 January 2018

Targeting Stat3 in cancer therapy

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21 January 2018

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21 January 2018

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21 January 2018

Role of STATs as downstream signal transducers in Src family kinase-mediated tumorigenesis

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21 January 2018

Constitutive activation of Stat3 by the Src and JAK tyrosine kinases participates in growth regulation of human breast carcinoma cells

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21 January 2018

Roles of activated Src and Stat3 signaling in melanoma tumor cell growth

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21 January 2018

Src kinases mediate STAT growth pathways in squamous cell carcinoma of the head and neck

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21 January 2018

FoxO3a transcriptional regulation of Bim controls apoptosis in paclitaxel-treated breast cancer cell lines

1 reference

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21 January 2018

Direct transcriptional regulation of Bim by FoxO3a mediates STI571-induced apoptosis in Bcr-Abl-expressing cells.

1 reference

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21 January 2018

Downregulation of Bim, a proapoptotic relative of Bcl-2, is a pivotal step in cytokine-initiated survival signaling in murine hematopoietic progenitors

1 reference

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21 January 2018

Apoptosis of non-small-cell lung cancer cell lines after paclitaxel treatment involves the BH3-only proapoptotic protein Bim.

1 reference

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21 January 2018

Microtubules, microtubule-interfering agents and apoptosis.

1 reference

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21 January 2018

Key roles of BIM-driven apoptosis in epithelial tumors and rational chemotherapy.

1 reference

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21 January 2018

The proapoptotic activity of the Bcl-2 family member Bim is regulated by interaction with the dynein motor complex

1 reference

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21 January 2018

Targeting mammalian target of rapamycin synergistically enhances chemotherapy-induced cytotoxicity in breast cancer cells

1 reference

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21 January 2018

IkappaB kinase promotes tumorigenesis through inhibition of forkhead FOXO3a

1 reference

https://api.crossref.org/works/10.1177%2F1534735406291499

21 January 2018

Activation of the ERK1/2 signaling pathway promotes phosphorylation and proteasome-dependent degradation of the BH3-only protein, Bim.

1 reference

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21 January 2018

COX-2 inhibits Fas-mediated apoptosis in cholangiocarcinoma cells

1 reference

https://api.crossref.org/works/10.1177%2F1534735406291499

21 January 2018

Enhancing Radiotherapy With Cyclooxygenase-2 Enzyme Inhibitors: A Rational Advance?

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21 January 2018

Cox-2 is needed but not sufficient for apoptosis induced by Cox-2 selective inhibitors in colon cancer cells.

1 reference

https://api.crossref.org/works/10.1177%2F1534735406291499

21 January 2018

Celecoxib-induced apoptosis in rat cholangiocarcinoma cells mediated by Akt inactivation and Bax translocation

1 reference

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21 January 2018

Inhibition of cyclooxygenase (COX)-2 expression by Tet-inducible COX-2 antisense cDNA in hormone-refractory prostate cancer significantly slows tumor growth and improves efficacy of chemotherapeutic drugs

1 reference

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21 January 2018

Cyclooxygenase-2 inhibitor celecoxib augments chemotherapeutic drug-induced apoptosis by enhancing activation of caspase-3 and -9 in prostate cancer cells

1 reference

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21 January 2018

Cyclooxygenase-2 inhibits novel ginseng metabolite-mediated apoptosis.

1 reference

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21 January 2018

Using cyclooxygenase-2 inhibitors as molecular platforms to develop a new class of apoptosis-inducing agents

1 reference

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21 January 2018

Cyclooxygenase-2 modulates the insulin-like growth factor axis in non-small-cell lung cancer

1 reference

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21 January 2018

Cyclooxygenase-2: potential role in regulation of drug efflux and multidrug resistance phenotype

1 reference

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21 January 2018

Impact of the cyclooxygenase system on doxorubicin-induced functional multidrug resistance 1 overexpression and doxorubicin sensitivity in acute myeloid leukemic HL-60 cells

1 reference

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21 January 2018

Cyclooxygenase-1 is a potential target for prevention and treatment of ovarian epithelial cancer

1 reference

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21 January 2018

Chemopreventive mechanisms of selenium

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21 January 2018

Apoptosis is a critical cellular event in cancer chemoprevention and chemotherapy by selenium compounds

1 reference

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21 January 2018

Induction of caspase-mediated apoptosis and cell-cycle G1 arrest by selenium metabolite methylselenol

1 reference

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21 January 2018

Methylseleninic acid sensitizes prostate cancer cells to TRAIL-mediated apoptosis

1 reference

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21 January 2018

PKB/AKT and ERK regulation of caspase-mediated apoptosis by methylseleninic acid in LNCaP prostate cancer cells

1 reference

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21 January 2018

Methylseleninic acid potentiates apoptosis induced by chemotherapeutic drugs in androgen-independent prostate cancer cells.

1 reference

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21 January 2018

Selective modulation of the therapeutic efficacy of anticancer drugs by selenium containing compounds against human tumor xenografts

1 reference

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Selenium protects against toxicity induced by anticancer drugs and augments antitumor activity: a highly selective, new, and novel approach for the treatment of solid tumors

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21 January 2018

Antisense to apoptosis inhibitors facilitates chemotherapy and TRAIL-induced death signaling

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21 January 2018

1alpha,25-dihydroxyvitamin D(3) (calcitriol) and its analogue, 19-nor-1alpha,25(OH)(2)D(2), potentiate the effects of ionising radiation on human prostate cancer cells

1 reference

https://api.crossref.org/works/10.1177%2F1534735406291499

21 January 2018

Potentiation of cell killing by fractionated radiation and suppression of proliferative recovery in MCF-7 breast tumor cells by the Vitamin D3 analog EB 1089.

1 reference

https://api.crossref.org/works/10.1177%2F1534735406291499

21 January 2018

EB1089, a synthetic analogue of vitamin D, induces apoptosis in breast cancer cells in vivo and in vitro

1 reference

https://api.crossref.org/works/10.1177%2F1534735406291499

21 January 2018

Molecular pathways involved in the antineoplastic effects of calcitriol on insulinoma cells

1 reference

https://api.crossref.org/works/10.1177%2F1534735406291499

21 January 2018

1,25-dihydroxyvitamin D3-induced apoptosis of retinoblastoma cells is associated with reciprocal changes of Bcl-2 and bax.

1 reference

https://api.crossref.org/works/10.1177%2F1534735406291499

21 January 2018

Bax, a predictive marker for therapeutic response to preoperative chemoradiotherapy in patients with rectal carcinoma.

1 reference

https://api.crossref.org/works/10.1177%2F1534735406291499

21 January 2018

Bcl-2 expression predicts radiotherapy failure in laryngeal cancer

1 reference

https://api.crossref.org/works/10.1177%2F1534735406291499

21 January 2018

Inhibition of prostate cancer growth by vitamin D: Regulation of target gene expression

1 reference

https://api.crossref.org/works/10.1177%2F1534735406291499

21 January 2018

Identification of a functional vitamin D response element in the human insulin-like growth factor binding protein-3 promoter

1 reference

https://api.crossref.org/works/10.1177%2F1534735406291499

21 January 2018

1alpha,25-dihydroxyvitamin D3 induced growth inhibition of PC-3 prostate cancer cells requires an active transforming growth factor beta signaling pathway

1 reference

https://api.crossref.org/works/10.1177%2F1534735406291499

21 January 2018

Regulation of multiple insulin-like growth factor binding protein genes by 1alpha,25-dihydroxyvitamin D3.

1 reference

https://api.crossref.org/works/10.1177%2F1534735406291499

21 January 2018

Insulin-like growth factor-binding protein-3 modulates expression of Bax and Bcl-2 and potentiates p53-independent radiation-induced apoptosis in human breast cancer cells

1 reference

https://api.crossref.org/works/10.1177%2F1534735406291499

21 January 2018

Signalling pathways involved in antiproliferative effects of IGFBP-3: a review

1 reference

https://api.crossref.org/works/10.1177%2F1534735406291499

21 January 2018

Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery

1 reference

https://api.crossref.org/works/10.1177%2F1534735406291499

21 January 2018

Akt-dependent and -independent survival signaling pathways utilized by insulin-like growth factor I.

1 reference

https://api.crossref.org/works/10.1177%2F1534735406291499

21 January 2018

Vitamin D2 analog 19-nor-1,25-dihydroxyvitamin D2: antitumor activity against leukemia, myeloma, and colon cancer cells

1 reference

https://api.crossref.org/works/10.1177%2F1534735406291499

21 January 2018

The vitamin D3 analog EB 1089 enhances the antiproliferative and apoptotic effects of adriamycin in MCF-7 breast tumor cells

1 reference

https://api.crossref.org/works/10.1177%2F1534735406291499

21 January 2018

Insulin-Like Growth Factor I (IGF-I) and IGF Binding Protein-1 Modulate Prostate Cancer Cell Growth and Apoptosis: Possible Mediators for the Effects of Diet and Exercise on Cancer Cell Survival

1 reference

https://api.crossref.org/works/10.1177%2F1534735406291499

21 January 2018

The role of insulin-like growth factor I and its receptor in cell growth, transformation, apoptosis, and chemoresistance in solid tumors

1 reference

https://api.crossref.org/works/10.1177%2F1534735406291499

21 January 2018

Expression of an IGF-I receptor dominant negative mutant induces apoptosis, inhibits tumorigenesis and enhances chemosensitivity in Ewing's sarcoma cells.

1 reference

https://api.crossref.org/works/10.1177%2F1534735406291499

21 January 2018

The insulin-like growth factor-I receptor kinase inhibitor, NVP-ADW742, sensitizes small cell lung cancer cell lines to the effects of chemotherapy

1 reference

https://api.crossref.org/works/10.1177%2F1534735406291499

21 January 2018

Insulin-like growth factor-I decreased etoposide-induced apoptosis in glioma cells by increasing bcl-2 expression and decreasing CPP32 activity.

1 reference

https://api.crossref.org/works/10.1177%2F1534735406291499

21 January 2018

Insulin-like growth factor I receptor blockade enhances chemotherapy and radiation responses and inhibits tumour growth in human gastric cancer xenografts.

1 reference

https://api.crossref.org/works/10.1177%2F1534735406291499

21 January 2018

Free and total insulin-like growth factor (IGF)-I levels decline during fasting: relationships with insulin and IGF-binding protein-1.

1 reference

https://api.crossref.org/works/10.1177%2F1534735406291499

21 January 2018

Rho prevents apoptosis through Bcl-2 expression: implications for interleukin-2 receptor signal transduction

1 reference

https://api.crossref.org/works/10.1177%2F1534735406291499

21 January 2018

Toxin-induced activation of Rho GTP-binding protein increases Bcl-2 expression and influences mitochondrial homeostasis

1 reference

https://api.crossref.org/works/10.1177%2F1534735406291499

21 January 2018

3-Hydroxy-3-methyl-glutaryl coenzyme A reductase inhibitors, atorvastatin and simvastatin, induce apoptosis of vascular smooth muscle cells by downregulation of Bcl-2 expression and Rho A prenylation

1 reference

https://api.crossref.org/works/10.1177%2F1534735406291499

21 January 2018

Rho protein inactivation induced apoptosis of cultured human endothelial cells

1 reference

https://api.crossref.org/works/10.1177%2F1534735406291499

21 January 2018

Effect of insulin on farnesyltransferase. Specificity of insulin action and potentiation of nuclear effects of insulin-like growth factor-1, epidermal growth factor, and platelet-derived growth factor

1 reference

https://api.crossref.org/works/10.1177%2F1534735406291499

21 January 2018

Insulin signals to prenyltransferases via the Shc branch of intracellular signaling

1 reference

https://api.crossref.org/works/10.1177%2F1534735406291499

21 January 2018

Policosanol modulates HMG-CoA reductase activity in cultured fibroblasts

1 reference

https://api.crossref.org/works/10.1177%2F1534735406291499

21 January 2018

Targeting multiple signaling pathways as a strategy for managing prostate cancer: multifocal signal modulation therapy

1 reference

https://api.crossref.org/works/10.1177%2F1534735406291499

21 January 2018

Strategies for multiple signalling inhibition

1 reference

https://api.crossref.org/works/10.1177%2F1534735406291499

21 January 2018

Continuous low-dose therapy with vinblastine and VEGF receptor-2 antibody induces sustained tumor regression without overt toxicity

1 reference

https://api.crossref.org/works/10.1177%2F1534735406291499

21 January 2018

The anti-angiogenic basis of metronomic chemotherapy

1 reference

https://api.crossref.org/works/10.1177%2F1534735406291499

21 January 2018

Thrombospondin 1, a mediator of the antiangiogenic effects of low-dose metronomic chemotherapy

1 reference

https://api.crossref.org/works/10.1177%2F1534735406291499

21 January 2018

Thrombospondin-1 associated with tumor microenvironment contributes to low-dose cyclophosphamide-mediated endothelial cell apoptosis and tumor growth suppression

1 reference

https://api.crossref.org/works/10.1177%2F1534735406291499

21 January 2018

The protective role of NF-kappaB and AP-1 in arsenite-induced apoptosis in aortic endothelial cells

1 reference

https://api.crossref.org/works/10.1177%2F1534735406291499

21 January 2018

Modulation of retinal endothelial cell behaviour by insulin-like growth factor I and somatostatin analogues: implications for diabetic retinopathy

1 reference

https://api.crossref.org/works/10.1177%2F1534735406291499

21 January 2018

Benefits of targeting both pericytes and endothelial cells in the tumor vasculature with kinase inhibitors

1 reference

https://api.crossref.org/works/10.1177%2F1534735406291499

21 January 2018

Vascular endothelial growth factor (VEGF)-mediated angiogenesis is associated with enhanced endothelial cell survival and induction of Bcl-2 expression

1 reference

https://api.crossref.org/works/10.1177%2F1534735406291499

21 January 2018

Endothelial cell survival and apoptosis in the tumor vasculature

1 reference

https://api.crossref.org/works/10.1177%2F1534735406291499

21 January 2018

Suppression of vascular endothelial growth factor-mediated endothelial cell protection by survivin targeting.

1 reference

https://api.crossref.org/works/10.1177%2F1534735406291499

21 January 2018

Vascular endothelial growth factor expression of intercellular adhesion molecule 1 (ICAM-1), vascular cell adhesion molecule 1 (VCAM-1), and E-selectin through nuclear factor-kappa B activation in endothelial cells

1 reference

https://api.crossref.org/works/10.1177%2F1534735406291499

21 January 2018

Bcl-2 acts in a proangiogenic signaling pathway through nuclear factor-kappaB and CXC chemokines.

1 reference

https://api.crossref.org/works/10.1177%2F1534735406291499

21 January 2018

A wholly nutritional 'multifocal angiostatic therapy' for control of disseminated cancer

1 reference

https://api.crossref.org/works/10.1177%2F1534735406291499

21 January 2018

Multifocal angiostatic therapy: an update

1 reference

https://api.crossref.org/works/10.1177%2F1534735406291499

21 January 2018

Eicosapentaenoic acid attenuates vascular endothelial growth factor-induced proliferation via inhibiting Flk-1 receptor expression in bovine carotid artery endothelial cells.

1 reference

https://api.crossref.org/works/10.1177%2F1534735406291499

21 January 2018

PDGFRbeta+ perivascular progenitor cells in tumours regulate pericyte differentiation and vascular survival

1 reference

https://api.crossref.org/works/10.1177%2F1534735406291499

21 January 2018

Endothelial/pericyte interactions

1 reference

https://api.crossref.org/works/10.1177%2F1534735406291499

21 January 2018

Inhibition of platelet-derived growth factor promotes pericyte loss and angiogenesis in ischemic retinopathy.

1 reference

https://api.crossref.org/works/10.1177%2F1534735406291499

21 January 2018

Selective ablation of immature blood vessels in established human tumors follows vascular endothelial growth factor withdrawal

1 reference

https://api.crossref.org/works/10.1177%2F1534735406291499

21 January 2018

Stable expression of angiopoietin-1 and other markers by cultured pericytes: phenotypic similarities to a subpopulation of cells in maturing vessels during later stages of angiogenesis in vivo

1 reference

https://api.crossref.org/works/10.1177%2F1534735406291499

21 January 2018

Tumor vessel development and maturation impose limits on the effectiveness of anti-vascular therapy

1 reference

https://api.crossref.org/works/10.1177%2F1534735406291499

21 January 2018

A multitargeted, metronomic, and maximum-tolerated dose "chemo-switch" regimen is antiangiogenic, producing objective responses and survival benefit in a mouse model of cancer.

1 reference

https://api.crossref.org/works/10.1177%2F1534735406291499

21 January 2018

Roles of NF-kappaB and SP-1 in oxidative stress-mediated induction of platelet-derived growth factor-B by TNFalpha in human endothelial cells

1 reference

https://api.crossref.org/works/10.1177%2F1534735406291499

21 January 2018

Nuclear factor-kappa B interacts functionally with the platelet-derived growth factor B-chain shear-stress response element in vascular endothelial cells exposed to fluid shear stress.

1 reference

https://api.crossref.org/works/10.1177%2F1534735406291499

21 January 2018

Diminished NF-kappaB activation and PDGF-B expression in glomerular endothelial cells subjected to chronic shear stress.

1 reference

https://api.crossref.org/works/10.1177%2F1534735406291499

21 January 2018

Green tea polyphenol epigallocatechin-3-gallate inhibits platelet-derived growth factor-induced proliferation of human hepatic stellate cell line LI90.

1 reference

https://api.crossref.org/works/10.1177%2F1534735406291499

21 January 2018

Green tea polyphenol epigallocatechin-3-gallate blocks PDGF-induced proliferation and migration of rat pancreatic stellate cells

1 reference

https://api.crossref.org/works/10.1177%2F1534735406291499

21 January 2018

Platelet-derived growth factor receptors: a therapeutic target in solid tumors

1 reference

https://api.crossref.org/works/10.1177%2F1534735406291499

21 January 2018

Targeting the platelet-derived growth factor receptor in antivascular therapy for human ovarian carcinoma

1 reference

https://api.crossref.org/works/10.1177%2F1534735406291499

21 January 2018

PDGF receptors-mediators of autocrine tumor growth and regulators of tumor vasculature and stroma

1 reference

https://api.crossref.org/works/10.1177%2F1534735406291499

21 January 2018

Lack of platelet effect with the aspirin analog, salsalate

1 reference

https://api.crossref.org/works/10.1177%2F1534735406291499

7 January 2021

based on heuristic

inferred from DOI database lookup

Metabolism of salsalate in normal subjects

1 reference

https://api.crossref.org/works/10.1177%2F1534735406291499

7 January 2021

based on heuristic

inferred from DOI database lookup

Overexpression of bax sensitizes human breast cancer MCF-7 cells to radiation-induced apoptosis

1 reference

https://api.crossref.org/works/10.1177%2F1534735406291499

7 January 2021

based on heuristic

inferred from DOI database lookup

Selenium-induced inhibition of angiogenesis in mammary cancer at chemopreventive levels of intake

1 reference

https://api.crossref.org/works/10.1177%2F1534735406291499

7 January 2021

based on heuristic

inferred from DOI database lookup

Marked induction of the IAP family antiapoptotic proteins survivin and XIAP by VEGF in vascular endothelial cells

1 reference

https://api.crossref.org/works/10.1177%2F1534735406291499

7 January 2021

based on heuristic

inferred from DOI database lookup

Anti-angiogenic potential of a cancer chemopreventive flavonoid antioxidant, silymarin: inhibition of key attributes of vascular endothelial cells and angiogenic cytokine secretion by cancer epithelial cells

1 reference

https://api.crossref.org/works/10.1177%2F1534735406291499

7 January 2021

based on heuristic

inferred from DOI database lookup

Apoptosis induction and inhibition of colon-26 tumour growth and angiogenesis: findings on COX-1 and COX-2 inhibitors in vitro & in vivo and topical diclofenac in hyaluronan

1 reference

https://api.crossref.org/works/10.1177%2F1534735406291499

7 January 2021

based on heuristic

inferred from DOI database lookup

Salicylsalicylic acid causes less gastroduodenal mucosal damage than enteric-coated aspirin. An endoscopic comparison

1 reference

https://api.crossref.org/works/10.1177%2F1534735406291499

7 January 2021

based on heuristic

inferred from DOI database lookup

Bax and Bcl-2 expressions predict response to radiotherapy in human cervical cancer

1 reference

https://api.crossref.org/works/10.1177%2F1534735406291499

7 January 2021

based on heuristic

inferred from DOI database lookup

Gastric cytoprotection by sodium salicylate

1 reference

https://api.crossref.org/works/10.1177%2F1534735406291499

7 January 2021

based on heuristic

inferred from DOI database lookup

Prognostic significance of Bax, Bcl-2, and p53 expressions in cervical squamous cell carcinoma treated by radiotherapy

1 reference

https://api.crossref.org/works/10.1177%2F1534735406291499

7 January 2021

based on heuristic

inferred from DOI database lookup

Analysis of ribosyl-modified, mixed backbone analogs of a bcl-2/bcl-xL antisense oligonucleotide

1 reference

https://api.crossref.org/works/10.1177%2F1534735406291499

7 January 2021

based on heuristic

inferred from DOI database lookup

Regulation of vascular endothelial growth factor-dependent retinal neovascularization by insulin-like growth factor-1 receptor

1 reference

https://api.crossref.org/works/10.1177%2F1534735406291499

7 January 2021

based on heuristic

inferred from DOI database lookup

Control of inducible chemoresistance: enhanced anti-tumor therapy through increased apoptosis by inhibition of NF-kappaB

1 reference

https://api.crossref.org/works/10.1177%2F1534735406291499

7 January 2021

based on heuristic

inferred from DOI database lookup

Inhibition of pp60c-Src reduces Bcl-XL expression and reverses the transformed phenotype of cells overexpressing EGF and HER-2 receptors

1 reference

https://api.crossref.org/works/10.1177%2F1534735406291499

7 January 2021

based on heuristic

inferred from DOI database lookup

Overexpression of the wild-type p53 gene inhibits NF-kappaB activity and synergizes with aspirin to induce apoptosis in human colon cancer cells

1 reference

https://api.crossref.org/works/10.1177%2F1534735406291499

7 January 2021

based on heuristic

inferred from DOI database lookup

Paclitaxel sensitivity of breast cancer cells with constitutively active NF-kappaB is enhanced by IkappaBalpha super-repressor and parthenolide

1 reference

https://api.crossref.org/works/10.1177%2F1534735406291499

7 January 2021

based on heuristic

inferred from DOI database lookup

NF- kappa B and chemoresistance: potentiation of cancer drugs via inhibition of NF- kappa B

1 reference

https://api.crossref.org/works/10.1177%2F1534735406291499

7 January 2021

based on heuristic

inferred from DOI database lookup

Hydrogen peroxide activates NFkappaB and the interleukin-6 promoter through NFkappaB-inducing kinase

1 reference

https://api.crossref.org/works/10.1177%2F1534735406291499

7 January 2021

based on heuristic

inferred from DOI database lookup

Insulin and IGF-I as determinants of low "Western" cancer rates in the rural third world

1 reference

https://api.crossref.org/works/10.1177%2F1534735406291499

7 January 2021

based on heuristic

inferred from DOI database lookup

Plant-derived monoterpenes suppress hamster kidney cell 3-hydroxy-3-methylglutaryl coenzyme a reductase synthesis at the post-transcriptional level.

1 reference

https://api.crossref.org/works/10.1177%2F1534735406291499

7 January 2021

based on heuristic

inferred from DOI database lookup

Mechanisms of the inhibitory effects of epigallocatechin-3 gallate on platelet-derived growth factor-BB-induced cell signaling and mitogenesis

1 reference

https://api.crossref.org/works/10.1177%2F1534735406291499

7 January 2021

based on heuristic

inferred from DOI database lookup

Combined inhibition of VEGF and PDGF signaling enforces tumor vessel regression by interfering with pericyte-mediated endothelial cell survival mechanisms

1 reference

https://api.crossref.org/works/10.1177%2F1534735406291499

7 January 2021

based on heuristic

inferred from DOI database lookup

FOXO-dependent expression of the proapoptotic protein Bim: pivotal role for apoptosis signaling in endothelial progenitor cells

1 reference

https://api.crossref.org/works/10.1177%2F1534735406291499

7 January 2021

based on heuristic

inferred from DOI database lookup

Inhibition of the growth of 12V-ras-transformed rat fibroblasts by acetylsalicylic acid correlates with inhibition of NF-kappa B.

1 reference

https://api.crossref.org/works/10.1177%2F1534735406291499

7 January 2021

based on heuristic

inferred from DOI database lookup

Effects of salsalate (nonacetylated salicylate) and aspirin on serum prostaglandins in humans

1 reference

https://api.crossref.org/works/10.1177%2F1534735406291499

7 January 2021

based on heuristic

inferred from DOI database lookup

bcl-2/bax ratio as a predictive marker for therapeutic response to radiotherapy in patients with rectal cancer.

1 reference

https://api.crossref.org/works/10.1177%2F1534735406291499

7 January 2021

based on heuristic

inferred from DOI database lookup

Impact of insulin-like growth factor receptor-I function on angiogenesis, growth, and metastasis of colon cancer

1 reference

https://api.crossref.org/works/10.1177%2F1534735406291499

7 January 2021

based on heuristic

inferred from DOI database lookup

Regulation of angiogenesis by controlling VEGF receptor

1 reference

https://api.crossref.org/works/10.1177%2F1534735406291499

7 January 2021

based on heuristic

inferred from DOI database lookup

The homeobox gene Gax inhibits angiogenesis through inhibition of nuclear factor-kappaB-dependent endothelial cell gene expression

1 reference

https://api.crossref.org/works/10.1177%2F1534735406291499

7 January 2021

based on heuristic

inferred from DOI database lookup

Loss of redox factor 1 decreases NF-kappaB activity and increases susceptibility of endothelial cells to apoptosis

1 reference

https://api.crossref.org/works/10.1177%2F1534735406291499

7 January 2021

based on heuristic

inferred from DOI database lookup

Studies of the isoprenoid-mediated inhibition of mevalonate synthesis applied to cancer chemotherapy and chemoprevention.

1 reference

https://api.crossref.org/works/10.1177%2F1534735406291499

7 January 2021

based on heuristic

inferred from DOI database lookup

Methyl selenium-induced vascular endothelial apoptosis is executed by caspases and principally mediated by p38 MAPK pathway

1 reference

https://api.crossref.org/works/10.1177%2F1534735406291499

7 January 2021

based on heuristic

inferred from DOI database lookup

The vitamin D3 analog EB 1089 enhances the response of human breast tumor cells to radiation.

1 reference

https://api.crossref.org/works/10.1177%2F1534735406291499

7 January 2021

based on heuristic

inferred from DOI database lookup

Vascular endothelial growth factor activates nuclear factor-kappaB and induces monocyte chemoattractant protein-1 in bovine retinal endothelial cells

1 reference

https://api.crossref.org/works/10.1177%2F1534735406291499

7 January 2021

based on heuristic

inferred from DOI database lookup

Comparison of serum salicylate levels and gastro-intestinal blood loss between salsalate (Disalcid)and other forms of salicylates

1 reference

https://api.crossref.org/works/10.1177%2F1534735406291499

7 January 2021

based on heuristic

inferred from DOI database lookup

Life and death in cancer. GADD45 alpha and gamma are critical regulators of NF-kappaB mediated escape from programmed cell death

1 reference

https://api.crossref.org/works/10.1177%2F1534735406291499

7 January 2021

based on heuristic

inferred from DOI database lookup

NFkappaB-dependent chemoresistance in solid tumors.

1 reference

https://api.crossref.org/works/10.1177%2F1534735406291499

7 January 2021

based on heuristic

inferred from DOI database lookup

Misoprostol dosage in the prevention of nonsteroidal anti-inflammatory drug-induced gastric and duodenal ulcers: a comparison of three regimens

1 reference

https://api.crossref.org/works/10.1177%2F1534735406291499

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1177/1534735406291499

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

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