(Q24300479)

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The α-helical content of the transmembrane domain of the British dementia protein-2 (Bri2) determines its processing by signal peptide peptidase-like 2b (SPPL2b)

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scholarly article

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The α-helical content of the transmembrane domain of the British dementia protein-2 (Bri2) determines its processing by signal peptide peptidase-like 2b (SPPL2b) (English)

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transmembrane protein

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Signal peptide peptidase like 2B

1 reference

GOA release 2020-03-11

Integral membrane protein 2B

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GOA release 2020-03-11

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based on heuristic

inferred from title

Christian Haass

7

object named as

Christian Haass

author given names

Christian

author last names

Haass

1 reference

PubMed publication ID

19 October 2023

1

object named as

Regina Fluhrer

author given names

Regina

author last names

Fluhrer

1 reference

PubMed publication ID

19 October 2023

author name string

Lucas Martin

2

author given names

Lucas

author last names

Martin

1 reference

PubMed publication ID

19 October 2023

Bärbel Klier

3

author given names

Bärbel

author last names

Klier

1 reference

PubMed publication ID

19 October 2023

Martina Haug-Kröper

4

author given names

Martina

author last names

Haug-Kröper

1 reference

PubMed publication ID

19 October 2023

Gudula Grammer

5

author given names

Gudula

author last names

Grammer

1 reference

PubMed publication ID

19 October 2023

Brigitte Nuscher

6

author given names

Brigitte

author last names

Nuscher

1 reference

PubMed publication ID

19 October 2023

language of work or name

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publication date

10 February 2012

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Journal of Biological Chemistry

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287

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7

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5156-63

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describes a project that uses

1 reference

Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3281599/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

Substrate requirements for SPPL2b-dependent regulated intramembrane proteolysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281599

19 March 2017

Regulated intramembrane proteolysis of Bri2 (Itm2b) by ADAM10 and SPPL2a/SPPL2b

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281599

19 March 2017

Consensus analysis of signal peptide peptidase and homologous human aspartic proteases reveals opposite topology of catalytic domains compared with presenilins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281599

19 March 2017

Furin mediates enhanced production of fibrillogenic ABri peptides in familial British dementia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281599

19 March 2017

A stop-codon mutation in the BRI gene associated with familial British dementia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281599

19 March 2017

Requirements for signal peptide peptidase-catalyzed intramembrane proteolysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281599

19 March 2017

Identification of signal peptide peptidase, a presenilin-type aspartic protease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281599

19 March 2017

Asparagine-proline sequence within membrane-spanning segment of SREBP triggers intramembrane cleavage by site-2 protease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281599

19 March 2017

Regulated intramembrane proteolysis: a control mechanism conserved from bacteria to humans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281599

19 March 2017

Two transmembrane aspartates in presenilin-1 required for presenilin endoproteolysis and gamma-secretase activity

1 reference

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7 April 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281599

27 September 2017

Structure, mechanism and inhibition of gamma-secretase and presenilin-like proteases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281599

27 September 2017

Aberrant amyloid precursor protein (APP) processing in hereditary forms of Alzheimer disease caused by APP familial Alzheimer disease mutations can be rescued by mutations in the APP GxxxG motif

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281599

27 September 2017

Update 1 of: Proteases universally recognize beta strands in their active sites

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281599

27 September 2017

Sequence-specific intramembrane proteolysis: identification of a recognition motif in rhomboid substrates

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281599

27 September 2017

Induced dimerization of the amyloid precursor protein leads to decreased amyloid-beta protein production

1 reference

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27 September 2017

Intramembrane-cleaving proteases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281599

27 September 2017

Intramembrane proteolysis by signal peptide peptidases: a comparative discussion of GXGD-type aspartyl proteases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281599

27 September 2017

Proteomic profiling of gamma-secretase substrates and mapping of substrate requirements

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281599

27 September 2017

Intramembrane proteolysis of GXGD-type aspartyl proteases is slowed by a familial Alzheimer disease-like mutation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281599

27 September 2017

Intramembrane proteolysis by gamma-secretase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281599

27 September 2017

The C-terminal PAL motif and transmembrane domain 9 of presenilin 1 are involved in the formation of the catalytic pore of the gamma-secretase.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281599

27 September 2017

Homophilic interactions of the amyloid precursor protein (APP) ectodomain are regulated by the loop region and affect beta-secretase cleavage of APP.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281599

27 September 2017

Cutting proteins within lipid bilayers: rhomboid structure and mechanism.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281599

27 September 2017

Amyloid beta-protein precursor juxtamembrane domain regulates specificity of gamma-secretase-dependent cleavages

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281599

27 September 2017

GxxxG motifs within the amyloid precursor protein transmembrane sequence are critical for the etiology of Abeta42.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281599

27 September 2017

C-terminal PAL motif of presenilin and presenilin homologues required for normal active site conformation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281599

27 September 2017

The presenilin C-terminus is required for ER-retention, nicastrin-binding and gamma-secretase activity

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27 September 2017

Substrate specificity of rhomboid intramembrane proteases is governed by helix-breaking residues in the substrate transmembrane domain

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27 September 2017

BRICHOS: a conserved domain in proteins associated with dementia, respiratory distress and cancer

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27 September 2017

A non-amyloidogenic function of BACE-2 in the secretory pathway

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27 September 2017

Glycine 384 is required for presenilin-1 function and is conserved in bacterial polytopic aspartyl proteases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281599

27 September 2017

Helical membrane protein folding, stability, and evolution

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281599

27 September 2017

The structural aspects of limited proteolysis of native proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3281599

30 May 2018

Transmembrane domain 9 of presenilin determines the dynamic conformation of the catalytic site of gamma-secretase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.328104

21 January 2018

Sequence features of substrates required for cleavage by GlpG, an Escherichia coli rhomboid protease.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.328104

21 January 2018

Gamma-secretase: proteasome of the membrane?

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.328104

21 January 2018

Proteolytic processing of familial British dementia-associated BRI variants: evidence for enhanced intracellular accumulation of amyloidogenic peptides

1 reference

https://pubmed.ncbi.nlm.nih.gov/22194595

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A measure of helical propensity for amino acids in membrane environments

1 reference

https://pubmed.ncbi.nlm.nih.gov/22194595

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1074/JBC.M111.328104

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

release_yd64kko6gzfk5jnz6xj3zhqlo4

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OpenCitations bibliographic resource ID

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Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

PMC publication ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

PubMed publication ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

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