(Q24316305)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17110379%20AND%20SRC:MED&resulttype=core&format=json

22 December 2019

title

A novel nuclear interactor of ARF and MDM2 (NIAM) that maintains chromosomal stability (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17110379%20AND%20SRC:MED&resulttype=core&format=json

Transforming growth factor beta regulator 1

22 December 2019

main subject

1 reference

protein localization to nucleoplasm

GOA release 2020-03-11

1 reference

Transforming growth factor beta regulated gene 1

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

author

Van S Tompkins

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17110379%20AND%20SRC:MED&resulttype=core&format=json

22 December 2019

Frederick E. Domann

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17110379%20AND%20SRC:MED&resulttype=core&format=json

22 December 2019

Dawn Quelle

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17110379%20AND%20SRC:MED&resulttype=core&format=json

22 December 2019

4

Tamara Lushnikova

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17110379%20AND%20SRC:MED&resulttype=core&format=json

22 December 2019

author name string

Jussara Hagen

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17110379%20AND%20SRC:MED&resulttype=core&format=json

22 December 2019

April A Frazier

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17110379%20AND%20SRC:MED&resulttype=core&format=json

22 December 2019

Matthew P Fitzgerald

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17110379%20AND%20SRC:MED&resulttype=core&format=json

22 December 2019

Anne di Tommaso

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17110379%20AND%20SRC:MED&resulttype=core&format=json

22 December 2019

Veronique Ladeveze

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17110379%20AND%20SRC:MED&resulttype=core&format=json

22 December 2019

Christine M Eischen

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17110379%20AND%20SRC:MED&resulttype=core&format=json

22 December 2019

language of work or name

English

0 references

publication date

16 November 2006

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17110379%20AND%20SRC:MED&resulttype=core&format=json

Journal of Biological Chemistry

22 December 2019

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17110379%20AND%20SRC:MED&resulttype=core&format=json

22 December 2019

volume

282

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17110379%20AND%20SRC:MED&resulttype=core&format=json

22 December 2019

page(s)

1322-1333

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17110379%20AND%20SRC:MED&resulttype=core&format=json

22 December 2019

issue

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17110379%20AND%20SRC:MED&resulttype=core&format=json

Alternative reading frames of the INK4a tumor suppressor gene encode two unrelated proteins capable of inducing cell cycle arrest

22 December 2019

cites work

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609612200

Tumor suppression by Ink4a-Arf: progress and puzzles

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609612200

Tumor suppression at the mouse INK4a locus mediated by the alternative reading frame product p19ARF

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609612200

ARF promotes MDM2 degradation and stabilizes p53: ARF-INK4a locus deletion impairs both the Rb and p53 tumor suppression pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609612200

The Ink4a tumor suppressor gene product, p19Arf, interacts with MDM2 and neutralizes MDM2's inhibition of p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609612200

Database of p53 gene somatic mutations in human tumors and cell lines: updated compilation and future prospects

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609612200

p53-independent functions of the p19(ARF) tumor suppressor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609612200

ARF function does not require p53 stabilization or Mdm2 relocalization

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609612200

p14ARF induces G2 arrest and apoptosis independently of p53 leading to regression of tumours established in nude mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609612200

p14ARF induces G2 cell cycle arrest in p53- and p21-deficient cells by down-regulating p34cdc2 kinase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609612200

Divorcing ARF and p53: an unsettled case

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609612200

Stabilization of p53 by p14ARF without relocation of MDM2 to the nucleolus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609612200

Nucleophosmin (B23) targets ARF to nucleoli and inhibits its function

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609612200

DNA damage disrupts the p14ARF-B23(nucleophosmin) interaction and triggers a transient subnuclear redistribution of p14ARF.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609612200

Role of nucleophosmin in embryonic development and tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609612200

Nucleophosmin is required for DNA integrity and p19Arf protein stability

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609612200

CARF is a novel protein that cooperates with mouse p19ARF (human p14ARF) in activating p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609612200

MdmX binding to ARF affects Mdm2 protein stability and p53 transactivation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609612200

Functional and physical interaction of the human ARF tumor suppressor with Tat-binding protein-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609612200

ARF-BP1/Mule is a critical mediator of the ARF tumor suppressor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609612200

Nucleolar Arf tumor suppressor inhibits ribosomal RNA processing

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609612200

Physical and functional interactions of the Arf tumor suppressor protein with nucleophosmin/B23

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609612200

Tumor suppressor ARF degrades B23, a nucleolar protein involved in ribosome biogenesis and cell proliferation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609612200

Myc-ARF (alternate reading frame) interaction inhibits the functions of Myc.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609612200

p19ARF directly and differentially controls the functions of c-Myc independently of p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609612200

Regulation of NF-kappaB and p53 through activation of ATR and Chk1 by the ARF tumour suppressor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609612200

p14ARF activates a Tip60-dependent and p53-independent ATM/ATR/CHK pathway in response to genotoxic stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609612200

DNA damage-induced cell-cycle arrest of hematopoietic cells is overridden by activation of the PI-3 kinase/Akt signaling pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609612200

Cooperative signals governing ARF-mdm2 interaction and nucleolar localization of the complex.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609612200

Identification of a cryptic nucleolar-localization signal in MDM2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609612200

High-efficiency transformation of mammalian cells by plasmid DNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609612200

P14ARF promotes accumulation of SUMO-1 conjugated (H)Mdm2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609612200

SUMO-1 modification activates the transcriptional response of p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609612200

A system for stable expression of short interfering RNAs in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609612200

Proteolytic cleavage of MLL generates a complex of N- and C-terminal fragments that confers protein stability and subnuclear localization

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609612200

MDM2--master regulator of the p53 tumor suppressor protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609612200

Association of p19(ARF) with Mdm2 inhibits ubiquitin ligase activity of Mdm2 for tumor suppressor p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609612200

Pancreatic cancer biology and genetics

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609612200

Genetic instabilities in human cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609612200

Loss of p53 and centrosome hyperamplification.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609612200

ONCOMINE: a cancer microarray database and integrated data-mining platform

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609612200

Diversity of gene expression in adenocarcinoma of the lung

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609612200

Multiclass cancer diagnosis using tumor gene expression signatures

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609612200

Gene expression profiling predicts clinical outcome of breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609612200

Exploration of global gene expression patterns in pancreatic adenocarcinoma using cDNA microarrays

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609612200

Gene expression patterns in renal cell carcinoma assessed by complementary DNA microarray.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609612200

Distinct types of diffuse large B-cell lymphoma identified by gene expression profiling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609612200

The ubiquitin ligase COP1 is a critical negative regulator of p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609612200

Pirh2, a p53-induced ubiquitin-protein ligase, promotes p53 degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609612200

The pathological response to DNA damage does not contribute to p53-mediated tumour suppression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609612200

Modulation of gene expression in the preimplantation mouse embryo by TGF-alpha and TGF-beta

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609612200

Cytostatic and apoptotic actions of TGF-beta in homeostasis and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609612200

TGF-beta signaling: positive and negative effects on tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609612200

Can chromosomal instability initiate tumorigenesis?

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609612200

Differential requirement for p19ARF in the p53-dependent arrest induced by DNA damage, microtubule disruption, and ribonucleotide depletion

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609612200

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609612200

Mdm2 binds to Nbs1 at sites of DNA damage and regulates double strand break repair.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609612200

21 January 2018

Aneuploidy and cancer

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609612200

Oncogenic Ras induces p19ARF and growth arrest in mouse embryo fibroblasts lacking p21Cip1 and p27Kip1 without activating cyclin D-dependent kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609612200

Aberrations of the p53 pathway components p53, MDM2 and CDKN2A appear independent in diffuse large B cell lymphoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609612200

Different cooperating effect of p21 or p27 deficiency in combination with INK4a/ARF deletion in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609612200

p53- and Mdm2-Independent Repression of NF-κB Transactivation by the ARF Tumor Suppressor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609612200

Correlation between centrosome abnormalities and chromosomal instability in human pancreatic cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609612200

7 January 2021

inferred from DOI database lookup

Inactivation of the INK4A/ARF locus frequently coexists with TP53 mutations in non-small cell lung cancer

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609612200

7 January 2021

inferred from DOI database lookup

Decreased Mdm2 expression inhibits tumor development induced by loss of ARF

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M609612200

7 January 2021

inferred from DOI database lookup

Identifiers

DOI

10.1074/JBC.M609612200

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17110379%20AND%20SRC:MED&resulttype=core&format=json

release_uukv77dt5bfpve62pccb3huo6u

22 December 2019

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/uukv77dt5bfpve62pccb3huo6u

24 November 2022

mapped directly with Wikidata item

1 reference