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Autophagosome dynamics in neurodegeneration at a glance
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scholarly article
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stated in
PubMed
review article
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stated in
Europe PubMed Central
title
Autophagosome dynamics in neurodegeneration at a glance
(English)
1 reference
stated in
PubMed
main subject
cell biology
0 references
autophagosome
0 references
neurodegeneration
1 reference
based on heuristic
inferred from title
author name string
Y. C. Wong
series ordinal
1
1 reference
stated in
Crossref
E. L. F. Holzbaur
series ordinal
2
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stated in
Crossref
language of work or name
English
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stated in
PubMed
publication date
1 April 2015
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stated in
PubMed
published in
Journal of Cell Science
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stated in
PubMed
volume
128
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stated in
PubMed
issue
7
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stated in
PubMed
page(s)
1259-67
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PubMed
cites work
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Short mitochondrial ARF triggers Parkin/PINK1-dependent mitophagy
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20 March 2017
AMBRA1 is able to induce mitophagy via LC3 binding, regardless of PARKIN and p62/SQSTM1
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Autophagic clearance of polyQ proteins mediated by ubiquitin-Atg8 adaptors of the conserved CUET protein family
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Genome-wide RNAi screen identifies the Parkinson disease GWAS risk locus SREBF1 as a regulator of mitophagy
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The mitochondrial deubiquitinase USP30 opposes parkin-mediated mitophagy
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Ubiquitin is phosphorylated by PINK1 to activate parkin
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Parkin is activated by PINK1-dependent phosphorylation of ubiquitin at Ser65
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C9ORF72, implicated in amytrophic lateral sclerosis and frontotemporal dementia, regulates endosomal trafficking
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20 March 2017
Cytosolic cleaved PINK1 represses Parkin translocation to mitochondria and mitophagy
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The Parkinson's disease-linked proteins Fbxo7 and Parkin interact to mediate mitophagy
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20 March 2017
The LIR motif - crucial for selective autophagy
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20 March 2017
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20 March 2017
Interplay of LRRK2 with chaperone-mediated autophagy
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20 March 2017
dnc-1/dynactin 1 knockdown disrupts transport of autophagosomes and induces motor neuron degeneration
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20 March 2017
RAB7L1 interacts with LRRK2 to modify intraneuronal protein sorting and Parkinson's disease risk
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20 March 2017
PINK1 and Parkin target Miro for phosphorylation and degradation to arrest mitochondrial motility
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20 March 2017
Leucine-rich repeat kinase 2 regulates autophagy through a calcium-dependent pathway involving NAADP
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20 March 2017
A hexanucleotide repeat expansion in C9ORF72 is the cause of chromosome 9p21-linked ALS-FTD
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20 March 2017
Expanded GGGGCC hexanucleotide repeat in noncoding region of C9ORF72 causes chromosome 9p-linked FTD and ALS
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20 March 2017
Phosphorylation of the autophagy receptor optineurin restricts Salmonella growth
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20 March 2017
The mitochondrial intramembrane protease PARL cleaves human Pink1 to regulate Pink1 trafficking
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20 March 2017
Exome sequencing reveals VCP mutations as a cause of familial ALS
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20 March 2017
PINK1 cleavage at position A103 by the mitochondrial protease PARL.
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20 March 2017
p62/SQSTM1 is required for Parkin-induced mitochondrial clustering but not mitophagy; VDAC1 is dispensable for both
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20 March 2017
Ubiquilin functions in autophagy and is degraded by chaperone-mediated autophagy
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20 March 2017
Disease-causing mutations in parkin impair mitochondrial ubiquitination, aggregation, and HDAC6-dependent mitophagy
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20 March 2017
Loss of ALS2/Alsin exacerbates motor dysfunction in a SOD1-expressing mouse ALS model by disturbing endolysosomal trafficking
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20 March 2017
PINK1 is selectively stabilized on impaired mitochondria to activate Parkin
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PubMed Central
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20 March 2017
XBP-1 deficiency in the nervous system protects against amyotrophic lateral sclerosis by increasing autophagy
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20 March 2017
Rapamycin rescues TDP-43 mislocalization and the associated low molecular mass neurofilament instability
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20 March 2017
LRRK2 regulates autophagic activity and localizes to specific membrane microdomains in a novel human genomic reporter cellular model
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20 March 2017
Parkin is recruited selectively to impaired mitochondria and promotes their autophagy
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20 March 2017
Huntingtin has a membrane association signal that can modulate huntingtin aggregation, nuclear entry and toxicity
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20 March 2017
Ambra1 regulates autophagy and development of the nervous system
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20 March 2017
Hereditary early-onset Parkinson's disease caused by mutations in PINK1
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20 March 2017
Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism
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20 March 2017
Huntingtin-associated protein 1 (HAP1) interacts with the p150Glued subunit of dynactin
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20 March 2017
Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease
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20 March 2017
A huntingtin-associated protein enriched in brain with implications for pathology
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20 March 2017
ESCRT-III dysfunction causes autophagosome accumulation and neurodegeneration
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20 March 2017
VCP/p97 is essential for maturation of ubiquitin-containing autophagosomes and this function is impaired by mutations that cause IBMPFD
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20 March 2017
Optineurin is an autophagy receptor for damaged mitochondria in parkin-mediated mitophagy that is disrupted by an ALS-linked mutation
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20 March 2017
Suppression of basal autophagy in neural cells causes neurodegenerative disease in mice
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20 March 2017
Loss of autophagy in the central nervous system causes neurodegeneration in mice
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20 March 2017
Charcot-Marie-Tooth disease type 2A caused by mutation in a microtubule motor KIF1Bbeta
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20 March 2017
Shaping the role of mitochondria in the pathogenesis of Huntington's disease
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20 March 2017
Regulation of intracellular accumulation of mutant Huntingtin by Beclin 1
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20 March 2017
Inhibition of mTOR induces autophagy and reduces toxicity of polyglutamine expansions in fly and mouse models of Huntington disease
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20 March 2017
Interaction of huntingtin-associated protein with dynactin P150Glued
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20 March 2017
Lysosomal proteolysis and autophagy require presenilin 1 and are disrupted by Alzheimer-related PS1 mutations
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20 March 2017
Essential role for autophagy protein Atg7 in the maintenance of axonal homeostasis and the prevention of axonal degeneration
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20 March 2017
The regulation of autophagosome dynamics by huntingtin and HAP1 is disrupted by expression of mutant huntingtin, leading to defective cargo degradation
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20 March 2017
Delivery of GABAARs to synapses is mediated by HAP1-KIF5 and disrupted by mutant huntingtin.
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20 March 2017
Induction of autophagy in axonal dystrophy and degeneration
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20 March 2017
Interaction of Huntingtin-associated protein-1 with kinesin light chain: implications in intracellular trafficking in neurons
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20 March 2017
p62/SQSTM1 forms protein aggregates degraded by autophagy and has a protective effect on huntingtin-induced cell death
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7 April 2017
The role of autophagy in neurodegenerative disease
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7 April 2017
Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization
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7 April 2017
Autophagy and aging
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7 April 2017
Proteasome and p97 mediate mitophagy and degradation of mitofusins induced by Parkin
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7 April 2017
Mitochondrial membrane potential regulates PINK1 import and proteolytic destabilization by PARL
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7 April 2017
Autophagy gone awry in neurodegenerative diseases
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7 April 2017
Mutations of optineurin in amyotrophic lateral sclerosis
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7 April 2017
PINK1 stabilized by mitochondrial depolarization recruits Parkin to damaged mitochondria and activates latent Parkin for mitophagy
1 reference
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PubMed Central
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7 April 2017
Impaired degradation of mutant alpha-synuclein by chaperone-mediated autophagy
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7 April 2017
PINK1 phosphorylates ubiquitin to activate Parkin E3 ubiquitin ligase activity
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7 April 2017
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7 April 2017
PINK1-dependent recruitment of Parkin to mitochondria in mitophagy
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7 April 2017
PINK1 is activated by mitochondrial membrane potential depolarization and stimulates Parkin E3 ligase activity by phosphorylating Serine 65
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7 April 2017
Aggregate-prone proteins with polyglutamine and polyalanine expansions are degraded by autophagy
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4379723
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7 April 2017
Formation of α-synuclein Lewy neurite-like aggregates in axons impedes the transport of distinct endosomes
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PubMed Central
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29 September 2017
Quantitative proteomics reveal a feedforward mechanism for mitochondrial PARKIN translocation and ubiquitin chain synthesis.
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4379723
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29 September 2017
PICALM modulates autophagy activity and tau accumulation
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4379723
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29 September 2017
Genetic deficiency of the mitochondrial protein PGAM5 causes a Parkinson's-like movement disorder
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4379723
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29 September 2017
USP8 regulates mitophagy by removing K6-linked ubiquitin conjugates from parkin
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4379723
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29 September 2017
Mitophagy of damaged mitochondria occurs locally in distal neuronal axons and requires PINK1 and Parkin
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4379723
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29 September 2017
Autophagy in microglia degrades extracellular β-amyloid fibrils and regulates the NLRP3 inflammasome
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4379723
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29 September 2017
PINK1 triggers autocatalytic activation of Parkin to specify cell fate decisions
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4379723
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29 September 2017
Autophagosome biogenesis in primary neurons follows an ordered and spatially regulated pathway
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4379723
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29 September 2017
Autophagy induction enhances TDP43 turnover and survival in neuronal ALS models.
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4379723
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29 September 2017
Integrated regulation of motor-driven organelle transport by scaffolding proteins
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4379723
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29 September 2017
A specific subset of E2 ubiquitin-conjugating enzymes regulate Parkin activation and mitophagy differently
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4379723
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29 September 2017
LC3 binding to the scaffolding protein JIP1 regulates processive dynein-driven transport of autophagosomes
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4379723
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29 September 2017
Cargo recognition and trafficking in selective autophagy
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4379723
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29 September 2017
The deubiquitinase USP15 antagonizes Parkin-mediated mitochondrial ubiquitination and mitophagy
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4379723
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29 September 2017
Mutation in VPS35 associated with Parkinson's disease impairs WASH complex association and inhibits autophagy
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4379723
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29 September 2017
Membrane recruitment of endogenous LRRK2 precedes its potent regulation of autophagy
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4379723
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29 September 2017
Nrf2 reduces levels of phosphorylated tau protein by inducing autophagy adaptor protein NDP52.
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4379723
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29 September 2017
Interactions between autophagy receptors and ubiquitin-like proteins form the molecular basis for selective autophagy.
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4379723
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29 September 2017
Identification of a post-translationally myristoylated autophagy-inducing domain released by caspase cleavage of huntingtin.
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4379723
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29 September 2017
Differential roles of the ubiquitin proteasome system and autophagy in the clearance of soluble and aggregated TDP-43 species
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4379723
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29 September 2017
The LC3 interactome at a glance
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4379723
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29 September 2017
Chaperone-mediated autophagy: roles in disease and aging
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4379723
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29 September 2017
Loss of iron triggers PINK1/Parkin-independent mitophagy
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4379723
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29 September 2017
The accumulation of misfolded proteins in the mitochondrial matrix is sensed by PINK1 to induce PARK2/Parkin-mediated mitophagy of polarized mitochondria
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4379723
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29 September 2017
PINK1 is degraded through the N-end rule pathway
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4379723
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29 September 2017
Bit-by-bit autophagic removal of parkin-labelled mitochondria
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4379723
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29 September 2017
Restricted mitochondrial protein acetylation initiates mitochondrial autophagy
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4379723
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29 September 2017
JIP1 regulates the directionality of APP axonal transport by coordinating kinesin and dynein motors
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4379723
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29 September 2017
Parkin- and PINK1-Dependent Mitophagy in Neurons: Will the Real Pathway Please Stand Up?
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4379723
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29 September 2017
Lewy body-like α-synuclein aggregates resist degradation and impair macroautophagy
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4379723
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29 September 2017
VCP is essential for mitochondrial quality control by PINK1/Parkin and this function is impaired by VCP mutations
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4379723
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29 September 2017
Regulation of mitophagy by the Gp78 E3 ubiquitin ligase
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4379723
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29 September 2017
Characterization of PINK1 (PTEN-induced putative kinase 1) mutations associated with Parkinson disease in mammalian cells and Drosophila
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4379723
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29 September 2017
PINK1-mediated phosphorylation of the Parkin ubiquitin-like domain primes mitochondrial translocation of Parkin and regulates mitophagy
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4379723
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29 September 2017
Ubiquitin-independent function of optineurin in autophagic clearance of protein aggregates
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4379723
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29 September 2017
Divergent roles of ALS-linked proteins FUS/TLS and TDP-43 intersect in processing long pre-mRNAs
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4379723
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29 September 2017
Glycogen synthase kinase 3 inhibition promotes lysosomal biogenesis and autophagic degradation of the amyloid-β precursor protein
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4379723
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29 September 2017
Loss of P-type ATPase ATP13A2/PARK9 function induces general lysosomal deficiency and leads to Parkinson disease neurodegeneration.
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4379723
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29 September 2017
Deficiency of ATP13A2 leads to lysosomal dysfunction, α-synuclein accumulation, and neurotoxicity
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4379723
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29 September 2017
Mitochondrial processing peptidase regulates PINK1 processing, import and Parkin recruitment
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4379723
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29 September 2017
Spatial parkin translocation and degradation of damaged mitochondria via mitophagy in live cortical neurons
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4379723
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29 September 2017
Autophagosomes initiate distally and mature during transport toward the cell soma in primary neurons
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4379723
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29 September 2017
Control of autophagy as a therapy for neurodegenerative disease
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4379723
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29 September 2017
Microautophagy: lesser-known self-eating
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4379723
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29 September 2017
Lysosomal proteolysis inhibition selectively disrupts axonal transport of degradative organelles and causes an Alzheimer's-like axonal dystrophy
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4379723
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29 September 2017
Long pre-mRNA depletion and RNA missplicing contribute to neuronal vulnerability from loss of TDP-43.
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4379723
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29 September 2017
DJ-1 acts in parallel to the PINK1/parkin pathway to control mitochondrial function and autophagy
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4379723
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29 September 2017
α-Synuclein impairs macroautophagy: implications for Parkinson's disease.
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4379723
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29 September 2017
Genome-wide analysis reveals mechanisms modulating autophagy in normal brain aging and in Alzheimer's disease.
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4379723
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29 September 2017
Loss of the Parkinson's disease-linked gene DJ-1 perturbs mitochondrial dynamics
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4379723
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29 September 2017
p62/SQSTM1 cooperates with Parkin for perinuclear clustering of depolarized mitochondria
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4379723
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29 September 2017
DJ-1 is critical for mitochondrial function and rescues PINK1 loss of function
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4379723
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29 September 2017
Retrograde axonal transport: pathways to cell death?
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4379723
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29 September 2017
Cargo recognition failure is responsible for inefficient autophagy in Huntington's disease
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4379723
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29 September 2017
Mutations in CHMP2B in lower motor neuron predominant amyotrophic lateral sclerosis (ALS).
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4379723
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29 September 2017
Valosin-containing protein (VCP) is required for autophagy and is disrupted in VCP disease
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4379723
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29 September 2017
DCTN1 mutations in Perry syndrome
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4379723
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29 September 2017
Rhomboid-7 and HtrA2/Omi act in a common pathway with the Parkinson's disease factors Pink1 and Parkin
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4379723
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29 September 2017
Autophagy induction and autophagosome clearance in neurons: relationship to autophagic pathology in Alzheimer's disease
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4379723
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29 September 2017
Functional multivesicular bodies are required for autophagic clearance of protein aggregates associated with neurodegenerative disease
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4379723
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29 September 2017
Huntingtin facilitates dynein/dynactin-mediated vesicle transport.
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4379723
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29 September 2017
Autophagy-mediated clearance of huntingtin aggregates triggered by the insulin-signaling pathway
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4379723
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29 September 2017
Macroautophagy--a novel Beta-amyloid peptide-generating pathway activated in Alzheimer's disease
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4379723
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29 September 2017
Dynein mutations impair autophagic clearance of aggregate-prone proteins
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4379723
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29 September 2017
Dynein- and activity-dependent retrograde transport of autophagosomes in neuronal axons
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4379723
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2 June 2018
Acetylation targets mutant huntingtin to autophagosomes for degradation
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4379723
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2 June 2018
Autophagy regulates amyotrophic lateral sclerosis-linked fused in sarcoma-positive stress granules in neurons.
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4379723
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27 November 2018
The ubiquitin-conjugating enzymes UBE2N, UBE2L3 and UBE2D2/3 are essential for Parkin-dependent mitophagy.
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4379723
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27 November 2018
Different dynamic movements of wild-type and pathogenic VCPs and their cofactors to damaged mitochondria in a Parkin-mediated mitochondrial quality control system.
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4379723
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27 November 2018
Aβ secretion and plaque formation depend on autophagy
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4379723
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27 November 2018
SQSTM1 mutations in familial and sporadic amyotrophic lateral sclerosis
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4379723
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27 November 2018
Serine 403 phosphorylation of p62/SQSTM1 regulates selective autophagic clearance of ubiquitinated proteins.
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4379723
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27 November 2018
Degradation of Amyotrophic Lateral Sclerosis-linked Mutant Cu,Zn-Superoxide Dismutase Proteins by Macroautophagy and the Proteasome
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4379723
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27 November 2018
Familial-associated mutations differentially disrupt the solubility, localization, binding and ubiquitination properties of parkin.
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4379723
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27 November 2018
Extensive involvement of autophagy in Alzheimer disease: an immuno-electron microscopy study.
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4379723
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27 November 2018
Autophagy regulates the processing of amino terminal huntingtin fragments
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4379723
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27 November 2018
α-Synuclein Is Degraded by Both Autophagy and the Proteasome
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4379723
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27 November 2018
Mutant dynactin in motor neuron disease.
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27 November 2018
Expression of A53T mutant but not wild-type alpha-synuclein in PC12 cells induces alterations of the ubiquitin-dependent degradation system, loss of dopamine release, and autophagic cell death.
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4379723
retrieved
27 November 2018
Autophagy in spinal cord motor neurons in sporadic amyotrophic lateral sclerosis
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/25829512
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1242/JCS.161216
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
942726
OpenCitations bibliographic resource ID
942726
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
942726
PMC publication ID
4379723
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
942726
PubMed publication ID
25829512
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
942726
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