(Q35015993)

5 August 2017

Structure, function, regulation and polymorphism and the clinical significance of human cytochrome P450 1A2. (English)

1 reference

5 August 2017

Shu-Feng Zhou

1

1 reference

5 August 2017

Bo Wang

series ordinal

2

1 reference

5 August 2017

Li-Ping Yang

series ordinal

3

1 reference

5 August 2017

Jun-Ping Liu

series ordinal

4

1 reference

5 August 2017

language of work or name

English

0 references

publication date

1 May 2010

1 reference

5 August 2017

Drug Metabolism Reviews

1 reference

5 August 2017

42

1 reference

5 August 2017

268-354

1 reference

5 August 2017

2

1 reference

Polymorphisms in metabolic genes related to tobacco smoke and the risk of gastric cancer in the European prospective investigation into cancer and nutrition.

5 August 2017

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Identification of novel polymorphisms in the 5' flanking region of CYP1A2, characterization of interethnic variability, and investigation of their functional significance.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Genetic polymorphism of CYP1A2 in Ethiopians affecting induction and expression: characterization of novel haplotypes with single-nucleotide polymorphisms in intron 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Identification of human cytochrome p450 isozymes involved in diphenhydramine N-demethylation.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Identification of a novel splice-site mutation in the CYP1A2 gene

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

The functions of animal microRNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Drug interaction potential of soy extract and Panax ginseng

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Pharmacokinetics and effect on caffeine metabolism of the proton pump inhibitors, omeprazole, lansoprazole, and pantoprazole

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Cytochrome P450 CYP1A1: wider roles in cancer progression and prevention

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Metabolism of the soyabean isoflavone daidzein by CYP1A2 and the extra-hepatic CYPs 1A1 and 1B1 affects biological activity

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Metabolism and disposition of GTS-21, a novel drug for Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

CYP1A2 genetic polymorphisms and adenocarcinoma lung cancer risk in the Tunisian population

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

An Evaluation of the Dose‐Dependent Inhibition of CYP1A2 by Rofecoxib Using Theophylline as a CYP1A2 Probe

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Structural and mechanistic aspects of transcriptional induction of cytochrome P450 1A1 by benzimidazole derivatives in rat hepatoma H4IIE cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Rofecoxib is a potent inhibitor of cytochrome P450 1A2: studies with tizanidine and caffeine in healthy subjects

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Effects of gender and moderate smoking on the pharmacokinetics and effects of the CYP1A2 substrate tizanidine

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Cytochrome P450 1A1/2 induction by antiparasitic drugs: dose-dependent increase in ethoxyresorufin O-deethylase activity and mRNA caused by quinine, primaquine and albendazole in HepG2 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Physiological and metabolic functions of melatonin

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

MicroRNAs: target recognition and regulatory functions

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

The influence of ethnic factors and gender on CYP1A2-mediated drug disposition: a comparative study in Caucasian and Chinese subjects using phenacetin as a marker substrate

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

The effect of ciprofloxacin on theophylline pharmacokinetics in healthy subjects.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Influence of the CYP1A2 inhibitor fluvoxamine on tacrine pharmacokinetics in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Thioridazine steady-state plasma concentrations are influenced by tobacco smoking and CYP2D6, but not by the CYP2C9 genotype

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Zileuton: clinical implications of 5-Lipoxygenase inhibition in severe airway disease

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Clozapine disposition covaries with CYP1A2 activity determined by a caffeine test

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

In vitro proguanil activation to cycloguanil by human liver microsomes is mediated by CYP3A isoforms as well as by S-mephenytoin hydroxylase

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

The metabolic sulfonation and side-chain oxidation of 3'-hydroxyisosafrole in the mouse and its inactivity as a hepatocarcinogen relative to 1'-hydroxysafrole

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Investigation of the influence of CYP1A2 and CYP2C19 genetic polymorphism on 2-Cyano-3-hydroxy-N-[4-(trifluoromethyl)phenyl]-2-butenamide (A77 1726) pharmacokinetics in leflunomide-treated patients with rheumatoid arthritis.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Genetic polymorphism of CYP1A2 and the toxicity of leflunomide treatment in rheumatoid arthritis patients

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Identification of the cytochrome P450 enzymes involved in the metabolism of cisapride: in vitro studies of potential co-medication interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Identification of the cytochromes P450 that catalyze coumarin 3,4-epoxidation and 3-hydroxylation

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Cytochrome P450 enzymes contributing to demethylation of maprotiline in man.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

In vitro metabolism of genistein and tangeretin by human and murine cytochrome P450s

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Ciprofloxacin strongly inhibits clozapine metabolism: two case reports

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Population pharmacokinetics of riluzole in patients with amyotrophic lateral sclerosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Riluzole. A review of its pharmacodynamic and pharmacokinetic properties and therapeutic potential in amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Studies on the in vivo and in vitro estrogenic activities of methoxychlor and its metabolites. Role of hepatic mono-oxygenase in methoxychlor activation

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Recursive partitioning for the prediction of cytochromes P450 2D6 and 1A2 inhibition: importance of the quality of the dataset.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Pharmacokinetics of clozapine and risperidone: a review of recent literature

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Origins and Mechanisms of miRNAs and siRNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Characterization of the Ah receptor-associated protein, ARA9

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Population pharmacokinetics and association between A77 1726 plasma concentrations and disease activity measures following administration of leflunomide to people with rheumatoid arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Urinary metabolite profiling reveals CYP1A2-mediated metabolism of NSC686288 (aminoflavone).

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

A conserved proline-rich sequence between the N-terminal signal-anchor and catalytic domains is required for assembly of functional cytochrome P450 2C2.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

The G-113A polymorphism in CYP1A2 affects the caffeine metabolic ratio in a Chinese population

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Simultaneous action of the flavonoid quercetin on cytochrome P450 (CYP) 1A2, CYP2A6, N-acetyltransferase and xanthine oxidase activity in healthy volunteers.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Differential metabolism of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) in mice humanized for CYP1A1 and CYP1A2.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Interaction with the aromatic hydrocarbon receptor, CYP1A induction, and mutagenicity of a series of diaminotoluenes: implications for their carcinogenicity

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Detection of three genetic polymorphisms in the 5'-flanking region and intron 1 of human CYP1A2 in the Japanese population.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Tight-binding inhibition by alpha-naphthoflavone of human cytochrome P450 1A2.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

A rapid computational filter for cytochrome P450 1A2 inhibition potential of compound libraries

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Metabolism of retinoids and arachidonic acid by human and mouse cytochrome P450 1b1

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Resveratrol is a selective human cytochrome P450 1A1 inhibitor

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Oxidation of ranitidine by isozymes of flavin-containing monooxygenase and cytochrome P450.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Comparison of (S)-mephenytoin and proguanil oxidation in vitro: contribution of several CYP isoforms

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Organization of the CYP1A cluster on human chromosome 15: implications for gene regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Coffee, CYP1A2 genotype, and risk of myocardial infarction

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Development of a human lymphoblastoid cell line constitutively expressing human CYP1B1 cDNA: substrate specificity with model substrates and promutagens

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Methoxychlor as a model for environmental estrogens

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Inhibition of human cytochrome P450 1A2 by flavones: a molecular modeling study.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Frequency of -163 C>A and 63 C>G single nucleotide polymorphism of cytochrome P450 1A2 in two African populations

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Activation of the aryl hydrocarbon receptor by structurally diverse exogenous and endogenous chemicals

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

The gastroprokinetic and antiemetic drug metoclopramide is a substrate and inhibitor of cytochrome P450 2D6.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

The contribution of genetically determined oxidation status to inter-individual variation in phenacetin disposition

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Organophosphorothionate pesticides inhibit the bioactivation of imipramine by human hepatic cytochrome P450s

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Lack of drug interaction between omeprazole, lansoprazole, pantoprazole and theophylline

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Imiquimod and resiquimod as novel immunomodulators

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

No effect of the CYP1A2*1F genotype on thioridazine, mesoridazine, sulforidazine plasma concentrations in psychiatric patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

CYP1A2 activity is an important determinant of clozapine dosage in schizophrenic patients

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

For dioxin-induced birth defects, mouse or human CYP1A2 in maternal liver protects whereas mouse CYP1A1 and CYP1B1 are inconsequential

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Phenotype of the Cyp1a1/1a2/1b1-/- triple-knockout mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Regulation of dioxin receptor function by omeprazole

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Differential selectivity of cytochrome P450 inhibitors against probe substrates in human and rat liver microsomes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Nonresponse to clozapine and ultrarapid CYP1A2 activity: clinical data and analysis of CYP1A2 gene

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Induction of cytochrome P450 enzymes in cultured precision-cut human liver slices

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Treatment-resistant schizophrenia

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Repression of aryl hydrocarbon receptor (AHR) signaling by AHR repressor: role of DNA binding and competition for AHR nuclear translocator

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Time response of cytochrome P450 1A2 activity on cessation of heavy smoking

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Assessment of CYP1A2 activity in clinical practice: why, how, and when?

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

A controlled trial of tacrine in Alzheimer's disease. The Tacrine Study Group

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Cytochrome 1A1 induction by primaquine in human hepatocytes and HepG2 cells: absence of binding to the aryl hydrocarbon receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Effects of a chargrilled meat diet on expression of CYP3A, CYP1A, and P-glycoprotein levels in healthy volunteers

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Effects of grapefruit juice and smoking on verapamil concentrations in steady state

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Characterization of xenobiotic responsive elements upstream from the drug-metabolizing cytochrome P-450c gene: a similarity to glucocorticoid regulatory elements

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

CYP2A13 metabolizes the substrates of human CYP1A2, phenacetin, and theophylline.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Role of CYP3A4 in the regulation of the aryl hydrocarbon receptor by omeprazole sulphide.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Allele-specific expression and gene methylation in the control of CYP1A2 mRNA level in human livers

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Detection of a new N-oxidized metabolite of flutamide, N-[4-nitro-3-(trifluoromethyl)phenyl]hydroxylamine, in human liver microsomes and urine of prostate cancer patients

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Assessing human risk to heterocyclic amines

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Tizanidine is mainly metabolized by cytochrome p450 1A2 in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Oral contraceptives containing ethinyl estradiol and gestodene markedly increase plasma concentrations and effects of tizanidine by inhibiting cytochrome P450 1A2.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Fluvoxamine drastically increases concentrations and effects of tizanidine: a potentially hazardous interaction

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Ciprofloxacin greatly increases concentrations and hypotensive effect of tizanidine by inhibiting its cytochrome P450 1A2-mediated presystemic metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Levobupivacaine: a new safer long acting local anaesthetic agent.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Protective interventions to prevent aflatoxin-induced carcinogenesis in developing countries

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Metabolism and disposition of imatinib mesylate in healthy volunteers

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Biotransformation of caffeine, paraxanthine, theobromine and theophylline by cDNA-expressed human CYP1A2 and CYP2E1

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Possible involvement of multiple human cytochrome P450 isoforms in the liver metabolism of propofol.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Variation in CYP1A2 activity and its clinical implications: influence of environmental factors and genetic polymorphisms

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Influence of genetic polymorphisms, smoking, gender and age on CYP1A2 activity in a Turkish population.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Clinical assessment of effects of botanical supplementation on cytochrome P450 phenotypes in the elderly: St John's wort, garlic oil, Panax ginseng and Ginkgo biloba

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Metabolism of theophylline by cDNA-expressed human cytochromes P-450.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Biotransformation of caffeine by cDNA-expressed human cytochromes P-450.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

The arylhydrocarbon receptor repressor (AhRR): structure, expression, and function

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Analysis of the transcriptional regulation and molecular function of the aryl hydrocarbon receptor repressor in human cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Arginine to lysine 108 substitution in recombinant CYP1A2 abolishes methoxyresorufin metabolism in lymphoblastoid cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Genotyping of four genetic polymorphisms in the CYP1A2 gene in the Egyptian population

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Plasma caffeine metabolite ratio (17X/137X) in vivo associated with G-2964A and C734A polymorphisms of human CYP1A2.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Inducibility of CYP1A2 by omeprazole in vivo related to the genetic polymorphism of CYP1A2.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Trazodone. A review of its pharmacology, therapeutic use in depression and therapeutic potential in other disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Pharmacokinetics and safety of imiquimod 5% cream in the treatment of actinic keratoses of the face, scalp, or hands and arms

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Liver deformation in Ahr-null mice: evidence for aberrant hepatic perfusion in early development

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Effects of caffeine intake on the pharmacokinetics of melatonin, a probe drug for CYP1A2 activity

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Structure and function of cytochromes P450: a comparative analysis of three crystal structures.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

MicroRNAs: small RNAs with a big role in gene regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Coffee and health: a review of recent human research

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

The effect of oral contraceptives on the pharmacokinetics of melatonin in healthy subjects with CYP1A2 g.-163C>A polymorphism

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Allelic expression imbalance of the human CYP3A4 gene and individual phenotypic status.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Time- and concentration-dependent changes in gene expression induced by benzo(a)pyrene in two human cell lines, MCF-7 and HepG2.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Endogenous hepatic expression of the hepatitis B virus X-associated protein 2 is adequate for maximal association with aryl hydrocarbon receptor-90-kDa heat shock protein complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Inducibility of cytochrome P450 1A1 and chemical carcinogenesis by benzo[a]pyrene in AhR repressor-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Identification of CYP1A2 as the main isoform for the phase I hydroxylated metabolism of genistein and a prodrug converting enzyme of methylated isoflavones

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Overcoming CYP1A1/1A2 mediated induction of metabolism by escalating erlotinib dose in current smokers

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Human CYP1A2: sequence, gene structure, comparison with the mouse and rat orthologous gene, and differences in liver 1A2 mRNA expression

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Influence of cytochrome P450 polymorphisms on drug therapies: pharmacogenetic, pharmacoepigenetic and clinical aspects

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Coffee, myocardial infarction, and CYP nomenclature.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Theoretical quantitative structure-activity relationships of flavone ligands interacting with cytochrome P450 1A1 and 1A2 isozymes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Involvement of the CYP1A subfamily in stereoselective metabolism of carvedilol in beta-naphthoflavone-treated Caco-2 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Role of Glu318 at the putative distal site in the catalytic function of cytochrome P450d

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Functional characterization of single nucleotide polymorphisms with amino acid substitution in CYP1A2, CYP2A6, and CYP2B6 found in the Japanese population

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Pharmacokinetics and pharmacodynamics of clozapine

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

ABCB1 and cytochrome P450 polymorphisms: clinical pharmacogenetics of clozapine.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Kinetics and inhibition by fluvoxamine of phenacetin O-deethylation in V79 cells expressing human CYP1A2.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Fluvoxamine Inhibition and Carbamazepine Induction of the Metabolism of Clozapine

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Human cytochrome p450 enzymes of importance for the bioactivation of methyleugenol to the proximate carcinogen 1'-hydroxymethyleugenol.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Human cytochrome p450 enzyme specificity for the bioactivation of estragole and related alkenylbenzenes.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Toward the evaluation of function in genetic variability: characterizing human SNP frequencies and establishing BAC-transgenic mice carrying the human CYP1A1_CYP1A2 locus

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Benzo(a)pyrene-caused increased G(1)-S transition requires the activation of c-Jun through p53-dependent PI-3K/Akt/ERK pathway in human embryo lung fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Polymorphisms affecting gene transcription and mRNA processing in pharmacogenetic candidate genes: detection through allelic expression imbalance in human target tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Effect of ciprofloxacin on the pharmacokinetics of ropivacaine

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Regioselectivity prediction of CYP1A2-mediated phase I metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

The effect of fluvoxamine on the pharmacokinetics, safety, and tolerability of ramosetron in healthy subjects

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

In vitro metabolism studies on the isoxazole ring scission in the anti-inflammatory agent lefluonomide to its active alpha-cyanoenol metabolite A771726: mechanistic similarities with the cytochrome P450-catalyzed dehydration of aldoximes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

The use of caffeine for enzyme assays: a critical appraisal

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Dominant contribution of P450 3A4 to the hepatic carcinogenic activation of aflatoxin B1.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Human P450 metabolism of warfarin

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

HepaRG cells as an in vitro model for evaluation of cytochrome P450 induction in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Cytochrome P450 induction by rifampicin in healthy subjects: determination using the Karolinska cocktail and the endogenous CYP3A4 marker 4beta-hydroxycholesterol

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Oxidative metabolism of flunarizine and cinnarizine by microsomes from B-lymphoblastoid cell lines expressing human cytochrome P450 enzymes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Tolfenamic acid is a potent CYP1A2 inhibitor in vitro but does not interact in vivo: correction for protein binding is needed for data interpretation

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Celecoxib is a CYP1A2 inhibitor in vitro but not in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

In vitro inhibition of CYP1A2 by model inhibitors, anti-inflammatory analgesics and female sex steroids: predictability of in vivo interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Extreme sinus bradycardia (30/min) with acute right heart failure under tizanidine (Sirdalud). Possible pharmacological interaction with rofecoxib (Vioxx)

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Carcinogenesis of the food mutagen PhIP in mice is independent of CYP1A2.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Interaction of pefloxacin and enoxacin with the human cytochrome P450 enzyme CYP1A2

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Contributions of CYP2D6, CYP2C9 and CYP2C19 to the biotransformation of E- and Z-doxepin in healthy volunteers

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Different contribution of CYP2C19 in the in vitro metabolism of three proton pump inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Identification of human liver cytochrome P450 isoforms involved in autoinduced metabolism of the antiangiogenic agent (Z)-5-[(1,2-dihydro-2-oxo-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-propanoic acid (TSU-68).

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Allele-specific gene expression uncovered

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Inhibitory effects of antiarrhythmic drugs on phenacetin O-deethylation catalysed by human CYP1A2.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Alosetron repeat dose pharmacokinetics, effects on enzyme activities, and influence of demographic factors

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Effect of alosetron on theophylline pharmacokinetics

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Induction and inhibition of cytochromes P450 by the St. John's wort constituent hyperforin in human hepatocyte cultures

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Predictive three-dimensional quantitative structure-activity relationship of cytochrome P450 1A2 inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

The relative contribution of human cytochrome P450 isoforms to the four caffeine oxidation pathways: an in vitro comparative study with cDNA-expressed P450s including CYP2C isoforms

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Relative contribution of rat cytochrome P450 isoforms to the metabolism of caffeine: the pathway and concentration dependence

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Xenobiotic metabolizing gene variants, dietary heterocyclic amine intake, and risk of prostate cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

ARNT-deficient mice and placental differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Effect of mutations at Lys250, Arg251, and Lys253 of cytochrome P450 1A2 on the catalytic activities and the bindings of bifunctional axial ligands.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Drug interactions with smoking

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Oxidative metabolism and genotoxic potential of major isoflavone phytoestrogens

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Effects of ciprofloxacin on the stereoselective disposition of mexiletine in man.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Differences in caffeine and paraxanthine metabolism between human and murine CYP1A2.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Uroporphyrinogen oxidation catalyzed by reconstituted cytochrome P450IA2

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Genetic aspects of porphyria cutanea tarda.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Brassica vegetables increase and apiaceous vegetables decrease cytochrome P450 1A2 activity in humans: changes in caffeine metabolite ratios in response to controlled vegetable diets

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

In vitro evaluation of potential in vivo probes for human flavin-containing monooxygenase (FMO): metabolism of benzydamine and caffeine by FMO and P450 isoforms

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Inhibition of human cytochrome P450 enzymes by 1,2-dithiole-3-thione, oltipraz and its derivatives, and sulforaphane

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Consumption of charcoal-broiled meat as an experimental tool for discerning CYP1A2-mediated drug metabolism in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Tacrine is not an ideal probe drug for measuring CYP1A2 activity in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Characterization of the oxidative metabolites of 17beta-estradiol and estrone formed by 15 selectively expressed human cytochrome p450 isoforms

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

CYP1A2 activity as a risk factor for bladder cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Homology modelling of human CYP1A2 based on the CYP2C5 crystallographic template structure.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Molecular modelling of CYP1 family enzymes CYP1A1, CYP1A2, CYP1A6 and CYP1B1 based on sequence homology with CYP102

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Polymorphisms of cytochrome P4501A2 and N-acetyltransferase genes, smoking, and risk of pancreatic cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Differential metabolism of gefitinib and erlotinib by human cytochrome P450 enzymes.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Cyp1a2(-/-) null mutant mice develop normally but show deficient drug metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Deletion of the aryl hydrocarbon receptor-associated protein 9 leads to cardiac malformation and embryonic lethality.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Glucuronidation of olanzapine by cDNA-expressed human UDP-glucuronosyltransferases and human liver microsomes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

CYP1A2 is the major isoform responsible for paeonol O-demethylation in human liver microsomes.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

The effect of reciprocal active site mutations in human cytochromes P450 1A1 and 1A2 on alkoxyresorufin metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Induction of CYP1A by benzo[k]fluoranthene in human hepatocytes: CYP1A1 or CYP1A2?

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

In vitro and in vivo evaluations of cytochrome P450 1A2 interactions with duloxetine

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Three-dimensional modelling of human cytochrome P450 1A2 and its interaction with caffeine and MeIQ.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

3D-QSAR methods on the basis of ligand-receptor complexes. Application of COMBINE and GRID/GOLPE methodologies to a series of CYP1A2 ligands

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Mechanism-based inhibition of human liver microsomal cytochrome P450 1A2 by zileuton, a 5-lipoxygenase inhibitor

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Association of genetic polymorphisms with serum estrogens measured multiple times during a 2-year period in premenopausal women

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Induction of CYP1A1. The AhR/DRE paradigm: transcription, receptor regulation, and expanding biological roles

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

CYP1A induction and human risk assessment: an evolving tale of in vitro and in vivo studies

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Metabolism of melatonin by human cytochromes p450.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Effects of prototypical microsomal enzyme inducers on cytochrome P450 expression in cultured human hepatocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Effects of trazodone and fluoxetine in the treatment of major depression: therapeutic pharmacokinetic and pharmacodynamic interactions through formation of meta-chlorophenylpiperazine.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Pharmacodynamics of carbamazepine-mediated induction of CYP3A4, CYP1A2, and Pgp as assessed by probe substrates midazolam, caffeine, and digoxin

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

The impact of glucuronidation on the bioactivation and DNA adduction of the cooked-food carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Comparative in vitro and in vivo inhibition of cytochrome P450 CYP1A2, CYP2D6, and CYP3A by H2-receptor antagonists

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Differential selectivity in carbamazepine-induced inactivation of cytochrome P450 enzymes in rat and human liver

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Effect of passive smoking on theophylline clearance in children

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Clinical pharmacokinetics of almotriptan, a serotonin 5-HT(1B/1D) receptor agonist for the treatment of migraine

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Cytochrome P450 genetic polymorphisms and the response to prasugrel: relationship to pharmacokinetic, pharmacodynamic, and clinical outcomes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Familial porphyria cutanea tarda: characterization of seven novel uroporphyrinogen decarboxylase mutations and frequency of common hemochromatosis alleles

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Expression and induction of CYP1A1/1A2, CYP2A6 and CYP3A4 in primary cultures of human hepatocytes: a 10-year follow-up

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Stereoselective differences in the cytochrome P450-dependent dealkylation and demethylenation of N-methyl-benzodioxolyl-butanamine (MBDB, Eden) enantiomers.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Effects of genetic polymorphism of CYP1A2 inducibility on the steady-state plasma concentrations of trazodone and its active metabolite m-chlorophenylpiperazine in depressed Japanese patients

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Estrogen-metabolizing gene polymorphisms in the assessment of female hormone-dependent cancer risk.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Theophylline metabolism: Variation and genetics

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Characterization of substrate specificity of dog CYP1A2 using CYP1A2-deficient and wild-type dog liver microsomes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

A review on biological control and metabolism of aflatoxin

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Drug interaction of tizanidine and fluvoxamine

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Identification of cytochrome P-450 1A (CYP1A) genes from two teleost fish, toadfish (Opsanus tau) and scup (Stenotomus chrysops), and phylogenetic analysis of CYP1A genes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Six novel nonsynonymous CYP1A2 gene polymorphisms: catalytic activities of the naturally occurring variant enzymes.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Omeprazole stimulates the induction of human insulin-like growth factor binding protein-1 through aryl hydrocarbon receptor activation

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Detection of gene x gene interactions in genome-wide association studies of human population data

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Comparison of CYP1A2 and NAT2 phenotypes between black and white smokers

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Effects of histone deacetylation and DNA methylation on the constitutive and TCDD-inducible expressions of the human CYP1 family in MCF-7 and HeLa cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Involvement of CYP1A2 in mexiletine metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

CYP2D6.10 present in human liver microsomes shows low catalytic activity and thermal stability.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Oxidation of 5-methoxy-N,N-diisopropyltryptamine in rat liver microsomes and recombinant cytochrome P450 enzymes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Oxidative metabolism of 5-methoxy-N,N-diisopropyltryptamine (Foxy) by human liver microsomes and recombinant cytochrome P450 enzymes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

An in vitro evaluation of the victim and perpetrator potential of the anticancer agent laromustine (VNP40101M), based on reaction phenotyping and inhibition and induction of cytochrome P450 enzymes.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Role of aryl hydrocarbon receptor-mediated induction of the CYP1 enzymes in environmental toxicity and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

The effect of the CYP1A2 *1F mutation on CYP1A2 inducibility in pregnant women

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Caffeine as a metabolic probe: a comparison of the metabolic ratios used to assess CYP1A2 activity

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Polymorphisms in the CYP1A2 gene and theophylline metabolism in patients with asthma

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Metabolic activation of heterocyclic amines and other procarcinogens in Salmonella typhimurium umu tester strains expressing human cytochrome P4501A1, 1A2, 1B1, 2C9, 2D6, 2E1, and 3A4 and human NADPH-P450 reductase and bacterial O-acetyltransferase

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Metabolism of a new local anesthetic, ropivacaine, by human hepatic cytochrome P450.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Genotoxic activation of the environmental pollutant 3,6-dinitrobenzo[e]pyrene in Salmonella typhimurium umu strains expressing human cytochrome P450 and N-acetyltransferase.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Phosphorylation analysis of 90 kDa heat shock protein within the cytosolic arylhydrocarbon receptor complex

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Inhibitory effects of amiodarone and its N-deethylated metabolite on human cytochrome P450 activities: prediction of in vivo drug interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Identification of the human cytochrome P450 isoforms mediating in vitro N-dealkylation of perphenazine

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Contributions of five human cytochrome P450 isoforms to the N-demethylation of clozapine in vitro at low and high concentrations

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Cytochrome P450 1A2 is a major determinant of lidocaine metabolism in vivo: effects of liver function

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Oxidation of the flavonoids galangin and kaempferide by human liver microsomes and CYP1A1, CYP1A2, and CYP2C9.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Phenotypic polymorphism and gender-related differences of CYP1A2 activity in a Chinese population

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Treatment-resistance to clozapine in association with ultrarapid CYP1A2 activity and the C-->A polymorphism in intron 1 of the CYP1A2 gene: effect of grapefruit juice and low-dose fluvoxamine

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

CYP1A2 activity as measured by a caffeine test predicts clozapine and active metabolite steady-state concentrationin patients with schizophrenia

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

CYP1A2 genotype modifies the association between coffee intake and the risk of hypertension.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Chemopreventive effects of natural dietary compounds on cancer development

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

MicroRNAs regulate CYP3A4 expression via direct and indirect targeting

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Selection and characterization of human cytochrome P450 1A2 mutants with altered catalytic properties

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Induction of CYP1A2 activity by carbamazepine in children using the caffeine breath test

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

A survey of genetic and epigenetic variation affecting human gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Distinction of CYP1A1 and CYP1A2 activity by selective inhibition using fluvoxamine and isosafrole

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Interaction between CYP1A2-T2467DELT polymorphism and smoking in adenocarcinoma and squamous cell carcinoma of the lung

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Influence of the genetic polymorphism in the 5'-noncoding region of the CYP1A2 gene on CYP1A2 phenotype and urinary mutagenicity in smokers

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Inhibition of human CYP1A2 oxidation of 5,6-dimethyl-xanthenone-4-acetic acid by acridines: a molecular modelling study

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Pathways of carbamazepine bioactivation in vitro I. Characterization of human cytochromes P450 responsible for the formation of 2- and 3-hydroxylated metabolites

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Carbamazepine: a 'blind' assessment of CVP-associated metabolism and interactions in human liver-derived in vitro systems

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Influence of ritonavir on olanzapine pharmacokinetics in healthy volunteers

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Evaluation of human liver slices and reporter gene assays as systems for predicting the cytochrome p450 induction potential of drugs in vivo in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Clinical pharmacokinetics of fluvoxamine

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Identification of cytochrome P450 enzymes involved in the metabolism of the new designer drug 4'-methyl-alpha-pyrrolidinobutyrophenone

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Caffeine N3-demethylation (CYP1A2) in a population with an increased exposure to polychlorinated biphenyls

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Role of CYP1A2 and CYP2E1 in the pentoxifylline ciprofloxacin drug interaction

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Subcellular localization of the aryl hydrocarbon receptor is modulated by the immunophilin homolog hepatitis B virus X-associated protein 2

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

The hsp90 Co-chaperone XAP2 alters importin beta recognition of the bipartite nuclear localization signal of the Ah receptor and represses transcriptional activity

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

The in vivo formation and repair of DNA adducts from 1'-hydroxysafrole.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Epistasis--the essential role of gene interactions in the structure and evolution of genetic systems

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Differential inhibition of human cytochrome P450 enzymes by epsilon-viniferin, the dimer of resveratrol: comparison with resveratrol and polyphenols from alcoholized beverages

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Involvement of cytochrome P450 1A2 in the biotransformation of trans-resveratrol in human liver microsomes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

An evaluation of potential mechanism-based inactivation of human drug metabolizing cytochromes P450 by monoamine oxidase inhibitors, including isoniazid.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Structures of human cytochrome P-450 2E1. Insights into the binding of inhibitors and both small molecular weight and fatty acid substrates

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

High-resolution crystal structure of cytochrome P450cam

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Inhibitory effects of seven components of danshen extract on catalytic activity of cytochrome P450 enzyme in human liver microsomes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Ciprofloxacin increases serum clozapine and N-desmethylclozapine: a study in patients with schizophrenia

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Mechanism-based inactivation of human cytochrome P450 1A2 by furafylline: detection of a 1:1 adduct to protein and evidence for the formation of a novel imidazomethide intermediate

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

The effects of CYP3A4 inhibition on erlotinib pharmacokinetics: computer-based simulation (SimCYP) predicts in vivo metabolic inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

The interindividual differences in the 3-demthylation of caffeine alias CYP1A2 is determined by both genetic and environmental factors

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Selective serotonin reuptake inhibitors and theophylline metabolism in human liver microsomes: potent inhibition by fluvoxamine

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Relative contribution of cytochromes P-450 and flavin-containing monoxygenases to the metabolism of albendazole by human liver microsomes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Carcinogenicity and toxicity of methoxychlor

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Antagonism by neuroleptics of neurotransmitter receptors of normal human brain in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Molecular analysis of patients of Sardinian descent with Crigler-Najjar syndrome type I

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Increase of cytochrome P450IA2 activity by omeprazole: evidence by the 13C-[N-3-methyl]-caffeine breath test in poor and extensive metabolizers of S-mephenytoin

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Influence of dose, cigarette smoking, age, sex, and metabolic activity on plasma clozapine concentrations: a predictive model and nomograms to aid clozapine dose adjustment and to assess compliance in individual patients

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Crystal structure of human cytochrome P450 2D6

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Comparative QSAR studies of CYP1A2 inhibitor flavonoids using 2D and 3D descriptors

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Expression and induction potential of cytochromes P450 in human cryopreserved hepatocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Clinical pharmacokinetics of leflunomide

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Development of the "Inje cocktail" for high-throughput evaluation of five human cytochrome P450 isoforms in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Polymorphisms in the cytochrome P450 CYP1A2 gene (CYP1A2) in colorectal cancer patients and controls: allele frequencies, linkage disequilibrium and influence on caffeine metabolism.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Functional significance of a C-->A polymorphism in intron 1 of the cytochrome P450 CYP1A2 gene tested with caffeine

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Effect of troglitazone on cytochrome P450 enzymes in primary cultures of human and rat hepatocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Comparative studies on the cytochrome p450-associated metabolism and interaction potential of selegiline between human liver-derived in vitro systems

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Genetic polymorphisms of estrogen metabolizing enzyme and breast cancer risk in Thai women.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

The metabolic disposition of [methoxy-14C]-labelled trans-anethole, estragole and p-propylanisole in human volunteers

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Adaptations for the oxidation of polycyclic aromatic hydrocarbons exhibited by the structure of human P450 1A2

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Pharmacological rationale for the clinical use of caffeine

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Structure of human microsomal cytochrome P450 2C8. Evidence for a peripheral fatty acid binding site

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

The effect of rofecoxib on the pharmacodynamics and pharmcokinetics of warfarin.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Structure of mammalian cytochrome P450 2B4 complexed with 4-(4-chlorophenyl)imidazole at 1.9-A resolution: insight into the range of P450 conformations and the coordination of redox partner binding

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

CYP1A1 and GSTM1 polymorphisms and lung cancer risk in Chinese populations: a meta-analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Metabolism of benzo[a]pyrene to trans-7,8-dihydroxy-7, 8-dihydrobenzo[a]pyrene by recombinant human cytochrome P450 1B1 and purified liver epoxide hydrolase.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Site-directed mutageneses of rat liver cytochrome P-450d: axial ligand and heme incorporation

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

CO binding studies of engineered cytochrome P-450ds: effects of mutations at putative distal sites in the presence of polycyclic hydrocarbons.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Benzo[a]pyrene carcinogenicity is lost in mice lacking the aryl hydrocarbon receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Lack of impact of CYP1A2 genetic polymorphism (C/A polymorphism at position 734 in intron 1 and G/A polymorphism at position -2964 in the 5'-flanking region of CYP1A2) on the plasma concentration of haloperidol in smoking male Japanese with schizoph

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Stereoselective epoxidation and hydration at the K-region of polycyclic aromatic hydrocarbons by cDNA-expressed cytochromes P450 1A1, 1A2, and epoxide hydrolase

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Metabolic activation of the potent carcinogen dibenzo[a,h]anthracene by cDNA-expressed human cytochromes P450.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Interactions of olomoucine II with human liver microsomal cytochromes P450.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Leflunomide or methotrexate for juvenile rheumatoid arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Rapid genotyping for relevant CYP1A2 alleles by pyrosequencing

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Contribution of CYP1A2 in the hepatic metabolism of melatonin: studies with isolated microsomal preparations and liver slices

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Metabolism of rofecoxib in vitro using human liver subcellular fractions

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Genetic variation in eleven phase I drug metabolism genes in an ethnically diverse population

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

A ligand for the aryl hydrocarbon receptor isolated from lung

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Single nucleotide polymorphisms and haplotypes of CYP1A2 in a Japanese population

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

The effect of enzyme inhibition on the metabolism and activation of tacrine by human liver microsomes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Identification of cytochrome p450 enzymes involved in the metabolism of 4'-methyl-alpha-pyrrolidinopropiophenone, a novel scheduled designer drug, in human liver microsomes.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Characterization of mutagen-activated cellular oncogenes that confer anchorage independence to human fibroblasts and tumorigenicity to NIH 3T3 cells: sequence analysis of an enzymatically amplified mutant HRAS allele

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Evidence for reductive activation of carcinogenic aristolochic acids by prostaglandin H synthase -- (32)P-postlabeling analysis of DNA adduct formation

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Carcinogenic aristolochic acids upon activation by DT-diaphorase form adducts found in DNA of patients with Chinese herbs nephropathy.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Human enzymes involved in the metabolic activation of carcinogenic aristolochic acids: evidence for reductive activation by cytochromes P450 1A1 and 1A2

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Structural analysis of CYP2R1 in complex with vitamin D3

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Effect of smoking and CYP2D6 polymorphisms on the extent of fluvoxamine-alprazolam interaction in patients with psychosomatic disease

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Interaction of the cytochrome P4501A2, SULT1A1 and NAT gene polymorphisms with smoking and dietary mutagen intake in modification of the risk of pancreatic cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Post-transcriptional regulation of human pregnane X receptor by micro-RNA affects the expression of cytochrome P450 3A4.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Phenotype-genotype analysis of CYP1A2 in Japanese patients receiving oral theophylline therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Accumulation of caffeine in healthy volunteers treated with furafylline

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

In vitro and in silico identification and characterization of thiabendazole as a mechanism-based inhibitor of CYP1A2 and simulation of possible pharmacokinetic drug-drug interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Metabolism of biochanin A and formononetin by human liver microsomes in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Failing the public health--rofecoxib, Merck, and the FDA.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

4-aminobiphenyl-induced liver and urinary bladder DNA adduct formation in Cyp1a2(-/-) and Cyp1a2(+/+) mice

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Isozyme- and species-specific susceptibility of cDNA-expressed CYP1A P-450s to different flavonoids.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

The cytochrome P450 1A2 active site: topology and perturbations caused by glutamic acid-318 and threonine-319 mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Characterization of the human hepatic cytochromes P450 involved in the in vitro oxidation of clozapine

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Activation of heterocyclic aromatic amines by rat and human liver microsomes and by purified rat and human cytochrome P450 1A2.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

A predominate role of CYP1A2 for the metabolism of nabumetone to the active metabolite, 6-methoxy-2-naphthylacetic acid, in human liver microsomes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

CYP1A-mediated metabolism of the Janus kinase-3 inhibitor 4-(4'-hydroxyphenyl)-amino-6,7-dimethoxyquinazoline: structural basis for inactivation by regioselective O-demethylation

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

A common regulatory region functions bidirectionally in transcriptional activation of the human CYP1A1 and CYP1A2 genes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Identification of the main human cytochrome P450 enzymes involved in safrole 1'-hydroxylation

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

The alkaloid rutaecarpine is a selective inhibitor of cytochrome P450 1A in mouse and human liver microsomes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Oxidation of aflatoxin B1 by bacterial recombinant human cytochrome P450 enzymes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Caffeine raises the serum melatonin level in healthy subjects: an indication of melatonin metabolism by cytochrome P450(CYP)1A2.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Relative contributions of the five major human cytochromes P450, 1A2, 2C9, 2C19, 2D6, and 3A4, to the hepatic metabolism of the proteasome inhibitor bortezomib

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Benzo[a]pyrene metabolism in rat fetal hepatocytes culture. Improved methodology and effect of substrate concentration

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

The effect of smoking and cytochrome P450 CYP1A2 genetic polymorphism on clozapine clearance and dose requirement

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Association between CYP1A2 activity and riluzole clearance in patients with amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Therapeutic drug monitoring of A77 1726, the active metabolite of leflunomide: serum concentrations predict response to treatment in patients with rheumatoid arthritis.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Rapidly progressive interstitial renal fibrosis in young women: association with slimming regimen including Chinese herbs

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Virtual screening and prediction of site of metabolism for cytochrome P450 1A2 ligands.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Classification of cytochrome P450 1A2 inhibitors and noninhibitors by machine learning techniques.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Variation in enzymes of arylamine procarcinogen biotransformation among bladder cancer patients and control subjects

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Relative contribution of CYP3A to amitriptyline clearance in humans: in vitro and in vivo studies

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Synthetic and natural compounds that interact with human cytochrome P450 1A2 and implications in drug development

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

The cytochrome P450 2B6 (CYP2B6) is the main catalyst of efavirenz primary and secondary metabolism: implication for HIV/AIDS therapy and utility of efavirenz as a substrate marker of CYP2B6 catalytic activity

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Does increased access to primary care reduce hospital readmissions? Veterans Affairs Cooperative Study Group on Primary Care and Hospital Readmission

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Isoniazid is a mechanism-based inhibitor of cytochrome P450 1A2, 2A6, 2C19 and 3A4 isoforms in human liver microsomes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

CYP1A1 and CYP1B1 polymorphisms and risk of lung cancer among never smokers: a population-based study

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

The structure of human cytochrome P450 2C9 complexed with flurbiprofen at 2.0-A resolution

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Mammalian microsomal cytochrome P450 monooxygenase: structural adaptations for membrane binding and functional diversity

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Crystal structures of human cytochrome P450 3A4 bound to metyrapone and progesterone

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Crystal structure of human cytochrome P450 2C9 with bound warfarin

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Many roads to maturity: microRNA biogenesis pathways and their regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Contribution of human cytochrome p-450 isoforms to the metabolism of the simplest phenothiazine neuroleptic promazine

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Covalent binding of carbamazepine reactive metabolites to P450 isoforms present in the skin.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Comparison of linkage disequilibrium patterns and haplotype structure of eight single nucleotide polymorphisms across the CYP1A2 gene between the Korean, and other populations registered in the International HapMap database

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

DNA sequence variation in a 3.7-kb noncoding sequence 5' of the CYP1A2 gene: implications for human population history and natural selection

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

The evolution of transcriptional regulation in eukaryotes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

MicroRNA control in the immune system: basic principles

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

7-Ethoxycoumarin O-deethylation catalyzed by cytochromes P450 1A2 and 2E1 in human liver microsomes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Roles of cytochromes P450 1A2 and 3A4 in the oxidation of estradiol and estrone in human liver microsomes.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Role of cDNA-expressed human cytochromes P450 in the metabolism of diazepam.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Structures of human microsomal cytochrome P450 2A6 complexed with coumarin and methoxsalen

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

The structure of human microsomal cytochrome P450 3A4 determined by X-ray crystallography to 2.05-A resolution

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Comparison of In Vitro and In Vivo Inhibition Potencies of Fluvoxamine toward CYP2C19

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Clinically significant interactions with drugs used in the treatment of tuberculosis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Omeprazole transactivates human CYP1A1 and CYP1A2 expression through the common regulatory region containing multiple xenobiotic-responsive elements

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Genetic determinants in the metabolism of bladder carcinogens in relation to risk of bladder cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Evaluation of cytochrome P450 probe substrates commonly used by the pharmaceutical industry to study in vitro drug interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Involvement of the xenobiotic response element (XRE) in Ah receptor-mediated induction of human UDP-glucuronosyltransferase 1A1.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

The contribution of UDP-glucuronosyltransferase 1A9 on CYP1A2-mediated genotoxicity by aromatic and heterocyclic amines

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Rate-determining steps in phenacetin oxidations by human cytochrome P450 1A2 and selected mutants

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Oxidations of p-alkoxyacylanilides catalyzed by human cytochrome P450 1A2: structure-activity relationships and simulation of rate constants of individual steps in catalysis.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Role of cytochrome P450 1A2 in bilirubin degradation Studies in Cyp1a2 (-/-) mutant mice

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Drug interactions with tobacco smoking. An update

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Determination of the inhibitory potential of 6 fluoroquinolones on CYP1A2 and CYP2C9 in human liver microsomes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Characterization of human cytochromes P450 involved in theophylline 8-hydroxylation

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Genotyping and site-directed mutagenesis of a cytochrome P450 meander Pro-X-Arg motif critical to CYP4B1 catalysis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Functional characterization of four allelic variants of human cytochrome P450 1A2.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Clinical outcomes and management of mechanism-based inhibition of cytochrome P450 3A4.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Therapeutic drugs that behave as mechanism-based inhibitors of cytochrome P450 3A4

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Interactions of herbs with cytochrome P450.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Predicting pharmacokinetics and drug interactions in patients from in vitro and in vivo models: the experience with 5,6-dimethylxanthenone-4-acetic acid (DMXAA), an anti-cancer drug eliminated mainly by conjugation.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Mechanism-based inhibition of cytochrome P450 3A4 by therapeutic drugs.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Insights into the structure, function, and regulation of human cytochrome P450 1A2.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Clinical pharmacogenetics and potential application in personalized medicine

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Herbal bioactivation: the good, the bad and the ugly

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

An update on clinical drug interactions with the herbal antidepressant St. John's wort

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Polymorphism of human cytochrome P450 enzymes and its clinical impact

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Insights into the substrate specificity, inhibitors, regulation, and polymorphisms and the clinical impact of human cytochrome P450 1A2.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Clinically important drug interactions potentially involving mechanism-based inhibition of cytochrome P450 3A4 and the role of therapeutic drug monitoring

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Metabolic activation of herbal and dietary constituents and its clinical and toxicological implications: an update

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Application of mechanism-based CYP inhibition for predicting drug-drug interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Mechanism-based inhibition of CYP1A2 by antofloxacin, an 8-NH2 derivative of levofloxacin in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Selection of human cytochrome P450 1A2 mutants with enhanced catalytic activity for heterocyclic amine N-hydroxylation

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Induction of CYP1A2 by heavy coffee consumption in Serbs and Swedes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Comparisons of CYP1A2 genetic polymorphisms, enzyme activity and the genotype-phenotype relationship in Swedes and Koreans

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Search for an association between the human CYP1A2 genotype and CYP1A2 metabolic phenotype

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Riluzole metabolism and CYP1A1/2 polymorphisms in patients with ALS

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Characterization of Diuron N-Demethylation by Mammalian Hepatic Microsomes and cDNA-Expressed Human Cytochrome P450 Enzymes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Effect of Caffeine Intake 12 or 24 Hours Prior to Melatonin Intake and CYP1A2*1F Polymorphism on CYP1A2 Phenotyping by Melatonin

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Different Mechanisms for Inhibition of Human Cytochromes P450 1A1, 1A2, and 1B1 by Polycyclic Aromatic Inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Selectivity of Polycyclic Inhibitors for Human Cytochrome P450s 1A1, 1A2, and 1B1

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

Roles of CYP2A6 and CYP2B6 in nicotine C-oxidation by human liver microsomes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602530903286476

10.3109/03602530903286476

21 January 2018

Identifiers

DOI

1 reference

5 August 2017

1 reference