(Q37131243)

18 August 2017

1 reference

title

Neuroprotection for Huntington's disease: ready, set, slow (English)

1 reference

18 August 2017

0 references

1

Steven M Hersch

1 reference

18 August 2017

H Diana Rosas

2

1 reference

18 August 2017

1 April 2008

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18 August 2017

1 reference

18 August 2017

5

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18 August 2017

2

1 reference

18 August 2017

226-236

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https://scigraph.springernature.com/pub.10.1016/j.nurt.2008.01.003

18 August 2017

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cites work

Expression profiling of Huntington's disease models suggests that brain-derived neurotrophic factor depletion plays a major role in striatal degeneration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359156

Perceptions of discrimination among persons who have undergone predictive testing for Huntington's disease

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359156

Therapeutic silencing of mutant huntingtin with siRNA attenuates striatal and cortical neuropathology and behavioral deficits

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359156

A small-molecule therapeutic lead for Huntington's disease: preclinical pharmacology and efficacy of C2-8 in the R6/2 transgenic mouse

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359156

Ubiquitin conjugating enzymes participate in polyglutamine protein aggregation

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359156

Widespread disruption of repressor element-1 silencing transcription factor/neuron-restrictive silencer factor occupancy at its target genes in Huntington's disease.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359156

Predictors of diagnosis in Huntington disease

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359156

Huntingtin interacting proteins are genetic modifiers of neurodegeneration

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359156

Small molecules enhance autophagy and reduce toxicity in Huntington's disease models.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359156

OGG1 initiates age-dependent CAG trinucleotide expansion in somatic cells

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359156

Drug targeting of dysregulated transcription in Huntington's disease

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359156

Role of brain-derived neurotrophic factor in Huntington's disease

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359156

Late stage care in Huntington's disease

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359156

Change in MRI striatal volumes as a biomarker in preclinical Huntington's disease

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359156

Proteasome activator enhances survival of Huntington's disease neuronal model cells

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359156

A systematic review of the treatment studies in Huntington's disease since 1990.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359156

The stress of misfolded proteins: C. elegans models for neurodegenerative disease and aging

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359156

Psychiatric disorders in preclinical Huntington's disease

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359156

PGC-1alpha, a new therapeutic target in Huntington's disease?

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359156

Oxidative damage in Huntington's disease pathogenesis

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359156

To know or not to know: a review of behaviour and suicidal ideation in preclinical Huntington's disease

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359156

Apoptotic cascades as possible targets for inhibiting cell death in Huntington's disease

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359156

Histone deacetylase inhibitors as therapeutics for polyglutamine disorders

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359156

Role of autophagy in the clearance of mutant huntingtin: a step towards therapy?

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359156

Mechanisms of disease: Histone modifications in Huntington's disease

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359156

Pharmacological management of Huntington's disease: an evidence-based review

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359156

Autophagy-mediated clearance of huntingtin aggregates triggered by the insulin-signaling pathway

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359156

Normal huntingtin function: an alternative approach to Huntington's disease

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359156

The ubiquitin-proteasome system in Huntington's disease.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359156

RNAi: a potential therapy for the dominantly inherited nucleotide repeat diseases

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359156

Clioquinol down-regulates mutant huntingtin expression in vitro and mitigates pathology in a Huntington's disease mouse model

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359156

The therapeutic role of creatine in Huntington's disease

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359156

Genome-wide expression profiling of human blood reveals biomarkers for Huntington's disease.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359156

Intrabody applications in neurological disorders: progress and future prospects

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359156

Translating therapies for Huntington's disease from genetic animal models to clinical trials

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359156

A potent small molecule inhibits polyglutamine aggregation in Huntington's disease neurons and suppresses neurodegeneration in vivo

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359156

Chemotherapy for the brain: the antitumor antibiotic mithramycin prolongs survival in a mouse model of Huntington's disease

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359156

Experimental therapeutics in transgenic mouse models of Huntington's disease

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359156

Huntington's disease: prospects for neuroprotective therapy 10 years after the discovery of the causative genetic mutation

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359156

Suberoylanilide hydroxamic acid, a histone deacetylase inhibitor, ameliorates motor deficits in a mouse model of Huntington's disease

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359156

Tauroursodeoxycholic acid, a bile acid, is neuroprotective in a transgenic animal model of Huntington's disease.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359156

Sp1 and TAFII130 transcriptional activity disrupted in early Huntington's disease

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359156

Histone deacetylase inhibitors arrest polyglutamine-dependent neurodegeneration in Drosophila

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359156

An overview of psychiatric symptoms in Huntington's disease

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359156

Loss of huntingtin-mediated BDNF gene transcription in Huntington's disease

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359156

Loss of normal huntingtin function: new developments in Huntington's disease research

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359156

The Gln-Ala repeat transcriptional activator CA150 interacts with huntingtin: neuropathologic and genetic evidence for a role in Huntington's disease pathogenesis

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359156

Minocycline inhibits caspase-1 and caspase-3 expression and delays mortality in a transgenic mouse model of Huntington disease

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359156

The Huntington's disease protein interacts with p53 and CREB-binding protein and represses transcription

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359156

Aberrant interactions of transcriptional repressor proteins with the Huntington's disease gene product, huntingtin

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359156

Transglutaminase aggregates huntingtin into nonamyloidogenic polymers, and its enzymatic activity increases in Huntington's disease brain nuclei

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359156

Aggregation of huntingtin in neuronal intranuclear inclusions and dystrophic neurites in brain

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359156

Formation of neuronal intranuclear inclusions underlies the neurological dysfunction in mice transgenic for the HD mutation

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359156

Normal and expanded Huntington's disease gene alleles produce distinguishable proteins due to translation across the CAG repeat.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359156

A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359156

Evidence for neuronal degeneration and dendritic plasticity in cortical pyramidal neurons of Huntington's disease: a quantitative Golgi study.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359156

Huntingtin is a cytoplasmic protein associated with vesicles in human and rat brain neurons

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359156

Cellular localization of the Huntington's disease protein and discrimination of the normal and mutated form

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359156

Histone deacetylase 6 inhibition compensates for the transport deficit in Huntington's disease by increasing tubulin acetylation

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359156

Ethical issues and policy analysis for genetic testing: Huntington's disease as a paradigm for diseases with a late onset

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359156

Aberrant A2A receptor function in peripheral blood cells in Huntington's disease

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359156

The cellular and subcellular localization of huntingtin-associated protein 1 (HAP1): comparison with huntingtin in rat and human.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359156

Caspase cleavage of mutant huntingtin precedes neurodegeneration in Huntington's disease.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359156

Altered proteasomal function due to the expression of polyglutamine-expanded truncated N-terminal huntingtin induces apoptosis by caspase activation through mitochondrial cytochrome c release

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359156

CREB-binding protein sequestration by expanded polyglutamine

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359156

Rate of functional decline in Huntington's disease. Huntington Study Group

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359156

A controlled trial of idebenone in Huntington's disease

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359156

Cleavage of huntingtin by apopain, a proapoptotic cysteine protease, is modulated by the polyglutamine tract

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359156

Modulation of nucleosome dynamics in Huntington's disease

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359156

Diffusion tensor imaging in presymptomatic and early Huntington's disease: Selective white matter pathology and its relationship to clinical measures.

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359156

fMRI biomarker of early neuronal dysfunction in presymptomatic Huntington's Disease.

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359156

Riluzole in Huntington's disease (HD): an open label study with one year follow up.

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359156

Neuroprotective effects of creatine in a transgenic mouse model of Huntington's disease.

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359156

Riluzole therapy in Huntington's disease (HD).

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359156

Nuclear and neuropil aggregates in Huntington's disease: relationship to neuropathology.

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359156

Toward understanding the molecular pathology of Huntington's disease.

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359156

Basal ganglia volume and proximity to onset in presymptomatic Huntington disease

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359156

A worldwide study of the Huntington's disease mutation. The sensitivity and specificity of measuring CAG repeats

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359156

Widespread expression of Huntington's disease gene (IT15) protein product

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359156

Proliferative and degenerative changes in striatal spiny neurons in Huntington's disease: a combined study using the section-Golgi method and calbindin D28k immunocytochemistry

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359156

Understanding the low uptake of presymptomatic DNA testing for Huntington's disease

27 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359156

De novo expansion of a (CAG)n repeat in sporadic Huntington's disease

27 June 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.NURT.2008.01.003

Molecular analysis of new mutations for Huntington's disease: intermediate alleles and sex of origin effects.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.NURT.2008.01.003

No going home for hospitalized Huntington's disease patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.NURT.2008.01.003

The impact of Huntington's disease on family life.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.NURT.2008.01.003

Regional and progressive thinning of the cortical ribbon in Huntington's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.NURT.2008.01.003

Regional cortical thinning in preclinical Huntington disease and its relationship to cognition

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.NURT.2008.01.003

Rate of caudate atrophy in presymptomatic and symptomatic stages of Huntington's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.NURT.2008.01.003

Functional brain changes in presymptomatic Huntington's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.NURT.2008.01.003

At risk for Huntington disease: The PHAROS (Prospective Huntington At Risk Observational Study) cohort enrolled

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.NURT.2008.01.003

Specific psychiatric manifestations among preclinical Huntington disease mutation carriers

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.NURT.2008.01.003

Psychiatric symptoms in Huntington's disease before diagnosis: the predict-HD study

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.NURT.2008.01.003

Oxidative stress parameters in plasma of Huntington's disease patients, asymptomatic Huntington's disease gene carriers and healthy subjects : a cross-sectional study

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.NURT.2008.01.003

Mitochondrial impairment in patients and asymptomatic mutation carriers of Huntington's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.NURT.2008.01.003

Preparing for preventive clinical trials: the Predict-HD study

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.NURT.2008.01.003

A new model for prediction of the age of onset and penetrance for Huntington's disease based on CAG length.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.NURT.2008.01.003

Adverse effects of predictive testing for Huntington disease underestimated: long-term effects 7-10 years after the test

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.NURT.2008.01.003

A randomized, double-blind, futility clinical trial of creatine and minocycline in early Parkinson disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.NURT.2008.01.003

Purification of neuronal inclusions of patients with Huntington's disease reveals a broad range of N-terminal fragments of expanded huntingtin and insoluble polymers

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.NURT.2008.01.003

Cleavage at the caspase-6 site is required for neuronal dysfunction and degeneration due to mutant huntingtin

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.NURT.2008.01.003

Dose ranging and efficacy study of high-dose coenzyme Q10 formulations in Huntington's disease mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.NURT.2008.01.003

Neuroprotective effects of synaptic modulation in Huntington's disease R6/2 mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.NURT.2008.01.003

Small molecule enhancers of rapamycin-induced TOR inhibition promote autophagy, reduce toxicity in Huntington's disease models and enhance killing of mycobacteria by macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.NURT.2008.01.003

Global changes to the ubiquitin system in Huntington's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.NURT.2008.01.003

Progressive loss of BDNF in a mouse model of Huntington's disease and rescue by BDNF delivery

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.NURT.2008.01.003

Aggregated polyglutamine peptides delivered to nuclei are toxic to mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.NURT.2008.01.003

Nuclear-targeting of mutant huntingtin fragments produces Huntington's disease-like phenotypes in transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.NURT.2008.01.003

Histones associated with downregulated genes are hypo-acetylated in Huntington's disease models

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.NURT.2008.01.003

Discovery of a novel small-molecule targeting selective clearance of mutant huntingtin fragments.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.NURT.2008.01.003

Creatine increase survival and delays motor symptoms in a transgenic animal model of Huntington's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.NURT.2008.01.003

Dichloroacetate exerts therapeutic effects in transgenic mouse models of Huntington's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.NURT.2008.01.003

Lipoic acid improves survival in transgenic mouse models of Huntington's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.NURT.2008.01.003

Ironing iron out in Parkinson's disease and other neurodegenerative diseases with iron chelators: a lesson from 6-hydroxydopamine and iron chelators, desferal and VK-28.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.NURT.2008.01.003

Riluzole in Huntington's disease: a 3-year, randomized controlled study

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.NURT.2008.01.003

Paroxetine retards disease onset and progression in Huntingtin mutant mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.NURT.2008.01.003

Neuroprotective effects of phenylbutyrate in the N171-82Q transgenic mouse model of Huntington's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.NURT.2008.01.003

Trial of d-alpha-tocopherol in Huntington's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.NURT.2008.01.003

High-dose creatine therapy for Huntington disease: a 2-year clinical and MRS study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.NURT.2008.01.003

Creatine in Huntington disease is safe, tolerable, bioavailable in brain and reduces serum 8OH2'dG.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.NURT.2008.01.003

CYTE-I-HD: phase I dose finding and tolerability study of cysteamine (Cystagon) in Huntington's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.NURT.2008.01.003

Ethyl-EPA in Huntington disease: a double-blind, randomized, placebo-controlled trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.NURT.2008.01.003

Dosage effects of riluzole in Huntington's disease: a multicenter placebo-controlled study

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.NURT.2008.01.003

Longitudinal evaluation of "presymptomatic" carriers of Huntington's disease.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359156

Histone Deacetylase Inhibition by Sodium Butyrate Chemotherapy Ameliorates the Neurodegenerative Phenotype in Huntington's Disease Mice

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359156

Transient and progressive electrophysiological alterations in the corticostriatal pathway in a mouse model of Huntington's disease.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359156

Therapeutic effects of cystamine in a murine model of Huntington's disease.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359156

Therapeutic effects of coenzyme Q10 and remacemide in transgenic mouse models of Huntington's disease.

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359156

A randomized, placebo-controlled trial of coenzyme Q10 and remacemide in Huntington's disease

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359156

Quantitative neuropathological changes in presymptomatic Huntington's disease

3 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2359156

Autophagy and neurodegeneration

3 September 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.NURT.2008.01.003

Interference by huntingtin and atrophin-1 with cbp-mediated transcription leading to cellular toxicity

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18394565

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Safety and tolerability of the free-radical scavenger OPC-14117 in Huntington's disease. The Huntington Study Group

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18394565

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Discovery of bioactive small-molecule inhibitor of poly adp-ribose polymerase: implications for energy-deficient cells

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18394565

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.NURT.2008.01.003

1 reference

PMC publication ID

2359156

Dimensions Publication ID

18 August 2017

0 references

1 reference

PMC publication ID

2359156

18 August 2017

PubMed publication ID

18394565

1 reference

PMC publication ID

2359156