(Q37931402)

25 August 2017

1 reference

title

The role of mitogen- and stress-activated protein kinase pathways in melanoma (English)

1 reference

25 August 2017

Pablo Lopez-Bergami

1

1 reference

25 August 2017

publication date

1 October 2011

1 reference

Pigment Cell & Melanoma Research

25 August 2017

published in

1 reference

25 August 2017

volume

24

1 reference

25 August 2017

issue

5

1 reference

25 August 2017

page(s)

902-921

1 reference

Preclinical studies of celastrol and acetyl isogambogic acid in melanoma.

25 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00908.X

Mitogenic and melanogenic stimulation of normal human melanocytes by melanotropic peptides

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00908.X

Blocking oncogenic Ras signaling for cancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00908.X

Tumor dormancy induced by downregulation of urokinase receptor in human carcinoma involves integrin and MAPK signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00908.X

Basal cancer cell survival involves JNK2 suppression of a novel JNK1/c-Jun/Bcl-3 apoptotic network

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00908.X

LPS induces melanogenesis through p38 MAPK activation in human melanocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00908.X

JNK supports survival in melanoma cells by controlling cell cycle arrest and apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00908.X

Phorbol ester-inducible genes contain a common cis element recognized by a TPA-modulated trans-acting factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00908.X

Oncogenic BRAF induces melanoma cell invasion by downregulating the cGMP-specific phosphodiesterase PDE5A.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00908.X

The many paths to p38 mitogen-activated protein kinase activation in the immune system

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00908.X

Pathways of oncogene-induced senescence in human melanocytic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00908.X

Oncogenic transformation by ras and fos is mediated by c-Jun N-terminal phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00908.X

p38 regulates pigmentation via proteasomal degradation of tyrosinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00908.X

Mutant B-RAF signaling and cyclin D1 regulate Cks1/S-phase kinase-associated protein 2-mediated degradation of p27Kip1 in human melanoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00908.X

Uses for JNK: the many and varied substrates of the c-Jun N-terminal kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00908.X

Clinical efficacy of a RAF inhibitor needs broad target blockade in BRAF-mutant melanoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00908.X

mda-9/Syntenin regulates the metastatic phenotype in human melanoma cells by activating nuclear factor-kappaB.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00908.X

mda-9/Syntenin promotes metastasis in human melanoma cells by activating c-Src

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00908.X

Src kinase activation is mandatory for MDA-9/syntenin-mediated activation of nuclear factor-kappaB.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00908.X

Mitogen-activated protein (MAP) kinase/MAP kinase phosphatase regulation: roles in cell growth, death, and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00908.X

p38 MAPK in development and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00908.X

Mechanism of p38 MAP kinase activation in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00908.X

Reduced MAP kinase phosphatase-1 degradation after p42/p44MAPK-dependent phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00908.X

p38 MAP kinase's emerging role as a tumor suppressor

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00908.X

Amplification of PPM1D in human tumors abrogates p53 tumor-suppressor activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00908.X

ERK and cell death: mechanisms of ERK-induced cell death--apoptosis, autophagy and senescence

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00908.X

Activation and function of the MAPKs and their substrates, the MAPK-activated protein kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00908.X

Mitf cooperates with Rb1 and activates p21Cip1 expression to regulate cell cycle progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00908.X

Improved survival with vemurafenib in melanoma with BRAF V600E mutation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00908.X

The tumor suppressor p16(INK4a) prevents cell transformation through inhibition of c-Jun phosphorylation and AP-1 activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00908.X

POU domain transcription factors: BRN2 as a regulator of melanocytic growth and tumourigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00908.X

BRAF gene amplification can promote acquired resistance to MEK inhibitors in cancer cells harboring the BRAF V600E mutation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00908.X

UV-induced expression of key component of the tanning process, the POMC and MC1R genes, is dependent on the p-38-activated upstream stimulating factor-1 (USF-1)

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00908.X

Frequent mutations in the MITF pathway in melanoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00908.X

Mechanisms and functions of p38 MAPK signalling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00908.X

p38 MAP-kinases pathway regulation, function and role in human diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00908.X

Somatic activation of KIT in distinct subtypes of melanoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00908.X

A new mouse model to explore the initiation, progression, and therapy of BRAFV600E-induced lung tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00908.X

Mutations of the BRAF gene in human cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00908.X

Signal transduction by the JNK group of MAP kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00908.X

Beta-catenin induces immortalization of melanocytes by suppressing p16INK4a expression and cooperates with N-Ras in melanoma development

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00908.X

An inhibitor of stress-activated MAP-kinases reduces invasion and MMP-2 expression of malignant melanoma cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00908.X

Anti-oncogenic role of the endoplasmic reticulum differentially activated by mutations in the MAPK pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00908.X

A novel NF-kappa B-inducing kinase-MAPK signaling pathway up-regulates NF-kappa B activity in melanoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00908.X

Oncogenic Braf induces melanocyte senescence and melanoma in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00908.X

MEK/ERK-mediated proliferation is negatively regulated by P38 map kinase in the human pancreatic cancer cell line, PANC-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00908.X

ErbB receptor tyrosine kinases contribute to proliferation of malignant melanoma cells: inhibition by gefitinib (ZD1839).

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00908.X

p38alpha MAP kinase as a sensor of reactive oxygen species in tumorigenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00908.X

Inhibition of cell proliferation and cell cycle progression by specific inhibition of basal JNK activity: evidence that mitotic Bcl-2 phosphorylation is JNK-independent

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00908.X

Liver tumor development. c-Jun antagonizes the proapoptotic activity of p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00908.X

MEK1 mutations confer resistance to MEK and B-RAF inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00908.X

Targeting PI3K signalling in cancer: opportunities, challenges and limitations

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00908.X

Positive crosstalk between ERK and p38 in melanoma stimulates migration and in vivo proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00908.X

Whole genome analysis of p38 SAPK-mediated gene expression upon stress.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00908.X

Tripping the switch fantastic: how a protein kinase cascade can convert graded inputs into switch-like outputs

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00908.X

Inhibition of Mutated, Activated BRAF in Metastatic Melanoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00908.X

Selective inhibition of JNK with a peptide inhibitor attenuates pain hypersensitivity and tumor growth in a mouse skin cancer pain model

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00908.X

Arachidonic acid stimulates cell adhesion through a novel p38 MAPK-RhoA signaling pathway that involves heat shock protein 27.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00908.X

Integrative genomic analyses identify MITF as a lineage survival oncogene amplified in malignant melanoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00908.X

Advances in melanoma senescence and potential clinical application.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00908.X

Melanocytic nevus-like hyperplasia and melanoma in transgenic BRAFV600E mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00908.X

Gene expression changes and signaling events associated with the direct antimelanoma effect of IFN-gamma

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00908.X

The Brn-2 transcription factor links activated BRAF to melanoma proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00908.X

The role of B-RAF in melanoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00908.X

Melanoma biology and new targeted therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00908.X

Patterns of somatic mutation in human cancer genomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00908.X

Activation mutations of human c-KIT resistant to imatinib mesylate are sensitive to the tyrosine kinase inhibitor PKC412.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00908.X

Targeting c-Jun and JunB proteins as potential anticancer cell therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00908.X

Regulation of mitogen-activated protein kinase signaling networks by G protein-coupled receptors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00908.X

PLX4032, a selective BRAF(V600E) kinase inhibitor, activates the ERK pathway and enhances cell migration and proliferation of BRAF melanoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00908.X

The pathways to tumor suppression via route p38.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00908.X

A systems biology analysis of metastatic melanoma using in-depth three-dimensional protein profiling

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00908.X

The BH3-only member Noxa causes apoptosis in melanoma cells by multiple pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00908.X

B-RAF: A contributor to the melanoma phenotype

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00908.X

Tetraspanin CD9 induces MMP-2 expression by activating p38 MAPK, JNK and c-Jun pathways in human melanoma cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00908.X

Induction of apoptosis by DC-81-indole conjugate agent through NF-kappaB and JNK/AP-1 pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00908.X

Ultrasensitivity in the mitogen-activated protein kinase cascade

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00908.X

Inflammatory signaling compromises cell responses to interferon alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00908.X

Role of TRAF2/GCK in melanoma sensitivity to UV-induced apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00908.X

Expression of ring finger-deleted TRAF2 sensitizes metastatic melanoma cells to apoptosis via up-regulation of p38, TNFalpha and suppression of NF-kappaB activities

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00908.X

COT drives resistance to RAF inhibition through MAP kinase pathway reactivation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00908.X

Confirmation of a BRAF mutation-associated gene expression signature in melanoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00908.X

Core signaling pathways in human pancreatic cancers revealed by global genomic analyses

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00908.X

Lack of cytoplasmic ERK activation is an independent adverse prognostic factor in primary cutaneous melanoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00908.X

p38alpha and p38delta mitogen-activated protein kinase isoforms regulate invasion and growth of head and neck squamous carcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00908.X

Phosphatase-mediated crosstalk between MAPK signaling pathways in the regulation of cell survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00908.X

Diverse somatic mutation patterns and pathway alterations in human cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00908.X

Celastrol inhibits tumor cell proliferation and promotes apoptosis through the activation of c-Jun N-terminal kinase and suppression of PI3 K/Akt signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00908.X

Gene expression signature associated with BRAF mutations in human primary cutaneous melanomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00908.X

B-RAF is a therapeutic target in melanoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00908.X

The regulation of AP-1 activity by mitogen-activated protein kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00908.X

The c-Jun NH2-terminal kinase 2 plays a dominant role in human epidermal neoplasia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00908.X

Inhibition of p38 MAPK enhances ABT-737-induced cell death in melanoma cell lines: novel regulation of PUMA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00908.X

Dual-specificity MAP kinase phosphatases (MKPs) and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00908.X

p38 MAP kinase is necessary for melanoma-mediated regulation of VE-cadherin disassembly

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00908.X

c-Jun N-terminal kinase is activated in non-small-cell lung cancer and promotes neoplastic transformation in human bronchial epithelial cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00908.X

Sphingosine-1-phosphate decreases melanin synthesis via sustained ERK activation and subsequent MITF degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00908.X

MKK6 increases the melanocyte dendricity through the regulation of Rho family GTPases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00908.X

Notch signaling suppresses p38 MAPK activity via induction of MKP-1 in myogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00908.X

Mitogen-activated protein kinases control p27/Kip1 expression and growth of human melanoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00908.X

ERK and PI3K negatively regulate STAT-transcriptional activities in human melanoma cells: implications towards sensitization to apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00908.X

The complexity of mitogen-activated protein kinases (MAPKs) made simple

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00908.X

Loss of E-cadherin leads to upregulation of NFkappaB activity in malignant melanoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00908.X

Opposite long-term regulation of c-Myc and p27Kip1 through overactivation of Raf-1 and the MEK/ERK module in proliferating human choroidal melanoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00908.X

MITF: master regulator of melanocyte development and melanoma oncogene

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00908.X

Sorafenib blocks the RAF/MEK/ERK pathway, inhibits tumor angiogenesis, and induces tumor cell apoptosis in hepatocellular carcinoma model PLC/PRF/5.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00908.X

Oncogenic BRAF regulates beta-Trcp expression and NF-kappaB activity in human melanoma cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00908.X

Regulatory role of tetraspanin CD9 in tumor-endothelial cell interaction during transendothelial invasion of melanoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00908.X

The long arm of BRAF V600E gets to mTORC1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00908.X

RACK1 mediates activation of JNK by protein kinase C [corrected].

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00908.X

Rewired ERK-JNK signaling pathways in melanoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00908.X

Understanding signaling cascades in melanoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00908.X

c-Jun regulates phosphoinositide-dependent kinase 1 transcription: implication for Akt and protein kinase C activities and melanoma tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00908.X

Emerging roles of ATF2 and the dynamic AP1 network in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00908.X

Inhibition of JNK2 disrupts anaphase and produces aneuploidy in mammalian cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00908.X

Graded mitogen-activated protein kinase activity precedes switch-like c-Fos induction in mammalian cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00908.X

RAS oncogenes: the first 30 years.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00908.X

Microphthalmia transcription factor is a target of the p38 MAPK pathway in response to receptor activator of NF-kappa B ligand signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00908.X

ERK and PDE4 cooperate to induce RAF isoform switching in melanoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00908.X

Specificity of receptor tyrosine kinase signaling: transient versus sustained extracellular signal-regulated kinase activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00908.X

How blocking Raf activates the MAPK pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00908.X

Integrating signals from RTKs to ERK/MAPK.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00908.X

The RAS/RAF/MEK/ERK and PI3K/AKT signaling pathways present molecular targets for the effective treatment of advanced melanoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00908.X

Platelet-activating factor mediates MMP-2 expression and activation via phosphorylation of cAMP-response element-binding protein and contributes to melanoma metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00908.X

Docetaxel-induced apoptosis of human melanoma is mediated by activation of c-Jun NH2-terminal kinase and inhibited by the mitogen-activated protein kinase extracellular signal-regulated kinase 1/2 pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00908.X

BRAFE600-associated senescence-like cell cycle arrest of human naevi

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00908.X

BRAF(E600) in benign and malignant human tumours

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00908.X

Inhibition of JNK reduces G2/M transit independent of p53, leading to endoreduplication, decreased proliferation, and apoptosis in breast cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00908.X

Oncogene-induced cell senescence--halting on the road to cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00908.X

Regulation of MAP Kinase Signaling Modules by Scaffold Proteins in Mammals

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00908.X

Melanomas acquire resistance to B-RAF(V600E) inhibition by RTK or N-RAS upregulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00908.X

Post-transcriptional regulation of melanin biosynthetic enzymes by cAMP and resveratrol in human melanocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00908.X

The role of the c-Jun N-terminal kinase 2-α-isoform in non-small cell lung carcinoma tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00908.X

Protein kinase C in melanoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00908.X

Stress-responsive JNK mitogen-activated protein kinase mediates aspirin-induced suppression of B16 melanoma cellular proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00908.X

Tunable signal processing in synthetic MAP kinase cascades

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00908.X

Differential regulation of MAP kinase signalling by dual-specificity protein phosphatases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00908.X

Identification of direct transcriptional targets of (V600E)BRAF/MEK signalling in melanoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00908.X

Recovery of phospho-ERK activity allows melanoma cells to escape from BRAF inhibitor therapy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00908.X

High frequency of BRAF mutations in nevi

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00908.X

Manipulation of redox signaling in mammalian cells enabled by controlled photogeneration of reactive oxygen species.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00908.X

Analysis of the tyrosine kinome in melanoma reveals recurrent mutations in ERBB4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00908.X

Hepatocyte growth factor/scatter factor activates proliferation in melanoma cells through p38 MAPK, ATF-2 and cyclin D1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00908.X

Mcl-1 cleavage and sustained phosphorylation of c-Jun-N-terminal kinase mediate melanoma apoptosis induced by 2-acetyl furanonaphthoquinone: roles of Bcl-2 and p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00908.X

Targeting the Raf-MEK-ERK mitogen-activated protein kinase cascade for the treatment of cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00908.X

Expression and transcriptional activity of AP-1, CRE, and URE binding proteins in B16 mouse melanoma subclones.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00908.X

Distinct roles for JNK1 and JNK2 in regulating JNK activity and c-Jun-dependent cell proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00908.X

Activation of the Mitf promoter by lipid-stimulated activation of p38-stress signalling to CREB.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00908.X

Cutaneous melanoma subtypes show different BRAF and NRAS mutation frequencies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00908.X

Involvement of the Ras/MAPK signaling pathway in the modulation of urokinase production and cellular invasiveness by transforming growth factor-beta(1) in transformed keratinocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00908.X

mda-7 (IL-24) Mediates selective apoptosis in human melanoma cells by inducing the coordinated overexpression of the GADD family of genes by means of p38 MAPK.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00908.X

Reduction in Raf kinase inhibitor protein expression is associated with increased Ras-extracellular signal-regulated kinase signaling in melanoma cell lines.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00908.X

Taxol-induced mitochondrial stress in melanoma cells is mediated by activation of c-Jun N-terminal kinase (JNK) and p38 pathways via uncoupling protein 2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00908.X

Inhibition of Siah2 ubiquitin ligase by vitamin K3 (menadione) attenuates hypoxia and MAPK signaling and blocks melanoma tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00908.X

A role for ATF2 in regulating MITF and melanoma development

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00908.X

Mutant V599EB-Raf regulates growth and vascular development of malignant melanoma tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00908.X

Hypoxic induction of HIF-1alpha and VEGF expression in head and neck squamous cell carcinoma lines is mediated by stress activated protein kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00908.X

Oncogenic B-RafV600E inhibits apoptosis and promotes ERK-dependent inactivation of Bad and Bim.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00908.X

Activation of c-Jun N-terminal kinase is essential for mitochondrial membrane potential change and apoptosis induced by doxycycline in melanoma cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00908.X

Specific inhibitor of MEK-mediated cross-talk between ERK and p38 MAPK during differentiation of human osteosarcoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00908.X

Guggulsterone inhibits tumor cell proliferation, induces S-phase arrest, and promotes apoptosis through activation of c-Jun N-terminal kinase, suppression of Akt pathway, and downregulation of antiapoptotic gene products.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00908.X

A pivotal role for ERK in the oncogenic behaviour of malignant melanoma?

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00908.X

Multiple signaling pathways must be targeted to overcome drug resistance in cell lines derived from melanoma metastases

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00908.X

Ki67 expression levels are a better marker of reduced melanoma growth following MEK inhibitor treatment than phospho-ERK levels.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00908.X

Increased cyclin D1 expression can mediate BRAF inhibitor resistance in BRAF V600E-mutated melanomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00908.X

Inhibition of growth and invasive ability of melanoma by inactivation of mutated BRAF with lentivirus-mediated RNA interference.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00908.X

A subtle change in p38 MAPK activity is sufficient to suppress in vivo tumorigenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00908.X

Erk 1/2 differentially regulates the expression from the 1G/2G single nucleotide polymorphism in the MMP-1 promoter in melanoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00908.X

NF-kappaB activation in melanoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00908.X

NF-kappaB mediates mitogen-activated protein kinase pathway-dependent iNOS expression in human melanoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00908.X

Frequent somatic mutations of GNAQ in uveal melanoma and blue naevi

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00908.X

Mutations in GNA11 in uveal melanoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00908.X

Mitogen-activated protein kinase inhibition induces translocation of Bmf to promote apoptosis in melanoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00908.X

Acquired resistance to BRAF inhibitors mediated by a RAF kinase switch in melanoma can be overcome by cotargeting MEK and IGF-1R/PI3K

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00908.X

21 January 2018

Jun, the oncoprotein.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00908.X

Increasing complexity of the Ras signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00908.X

Dissecting therapeutic resistance to RAF inhibition in melanoma by tumor genomic profiling

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00908.X

Signal integration by JNK and p38 MAPK pathways in cancer development

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00908.X

Plumbagin induces cell cycle arrest and apoptosis through reactive oxygen species/c-Jun N-terminal kinase pathways in human melanoma A375.S2 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00908.X

Wnt5a signaling directly affects cell motility and invasion of metastatic melanoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00908.X

Oncogenic BRAF regulates melanoma proliferation through the lineage specific factor MITF.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00908.X

Role of mitogen-activated protein kinase kinase 4 in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00908.X

Induction of beta3-integrin gene expression by sustained activation of the Ras-regulated Raf-MEK-extracellular signal-regulated kinase signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00908.X

Expression of c-jun, jun-B, and c-fos Proto-Oncogenes in Human Primary Melanocytes and Metastatic Melanomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00908.X

RASSF1A suppresses melanoma development by modulating apoptosis and cell-cycle progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00908.X

The extracellular signal-regulated kinase: multiple substrates regulate diverse cellular functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00908.X

Pyridinyl imidazole inhibitors of p38 mitogen-activated protein kinase bind in the ATP site

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00908.X

A novel amplification target, DUSP26, promotes anaplastic thyroid cancer cell growth by inhibiting p38 MAPK activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00908.X

The role of BRAF mutation and p53 inactivation during transformation of a subpopulation of primary human melanocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00908.X

The subcellular localization of MEK and ERK--a novel nuclear translocation signal (NTS) paves a way to the nucleus

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00908.X

Oncogenic B-RAF negatively regulates the tumor suppressor LKB1 to promote melanoma cell proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00908.X

Activation of Jun N-terminal kinase is a mediator of vincristine-induced apoptosis of melanoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00908.X

Activation of the extracellular signal regulated kinase (ERK) pathway in human melanoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00908.X

Adhesion control of cyclin D1 and p27Kip1 levels is deregulated in melanoma cells through BRAF-MEK-ERK signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1755-148X.2011.00908.X

10.1111/J.1755-148X.2011.00908.X

21 January 2018

Identifiers

DOI

1 reference

25 August 2017

1 reference