(Q37956513)

25 August 2017

Recent rodent models for Alzheimer's disease: clinical implications and basic research (English)

1 reference

25 August 2017

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Adrian G Palacios

3

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Roger Chung

object named as

Roger S Chung

6

0 references

Gilles J. Guillemin

object named as

Gilles J Guillemin

8

0 references

Perminder Sachdev

object named as

Perminder Sachdev

7

0 references

author name string

Nady Braidy

1

1 reference

25 August 2017

Pablo Muñoz

2

1 reference

25 August 2017

Gloria Castellano-Gonzalez

4

1 reference

25 August 2017

Nibaldo C Inestrosa

5

1 reference

25 August 2017

16 November 2011

1 reference

Journal of Neural Transmission

25 August 2017

1 reference

25 August 2017

119

1 reference

25 August 2017

2

1 reference

25 August 2017

173-195

1 reference

https://scigraph.springernature.com/pub.10.1007/s00702-011-0731-5

25 August 2017

0 references

cites work

Promotion of hyperphosphorylation by frontotemporal dementia tau mutations

1 reference

https://api.crossref.org/works/10.1007%2FS00702-011-0731-5

Polymerization of hyperphosphorylated tau into filaments eliminates its inhibitory activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-011-0731-5

Alzheimer's disease hyperphosphorylated tau sequesters normal tau into tangles of filaments and disassembles microtubules.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-011-0731-5

Inhibitory role for dual specificity phosphatase VHR in T cell antigen receptor and CD28-induced Erk and Jnk activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-011-0731-5

Microglia, amyloid and dementia in alzheimer disease. A correlative study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-011-0731-5

Discovery of gamma-secretase inhibitors efficacious in a transgenic animal model of Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-011-0731-5

Immunotherapy targeting pathological tau conformers in a tangle mouse model reduces brain pathology with associated functional improvements.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-011-0731-5

Human and rodent amyloid-beta peptides differentially bind heme: relevance to the human susceptibility to Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-011-0731-5

Preventing familial amyotrophic lateral sclerosis: is a clinical trial feasible?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-011-0731-5

Senile plaques and neurofibrillary changes in the brain of an aged lemurian primate, Microcebus murinus

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-011-0731-5

Identification of amyloid beta protein in the brain of the small, short-lived lemurian primate Microcebus murinus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-011-0731-5

Microcebus murinus: a useful primate model for human cerebral aging and Alzheimer's disease?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-011-0731-5

Immunotherapy targeting pathological tau prevents cognitive decline in a new tangle mouse model

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-011-0731-5

Role of apoE/Abeta interactions in Alzheimer's disease: insights from transgenic mouse models

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-011-0731-5

The chick embryo appears as a natural model for research in beta-amyloid precursor protein processing.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-011-0731-5

Transgenic nonhuman primates for neurodegenerative diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-011-0731-5

Treatment with a copper-zinc chelator markedly and rapidly inhibits beta-amyloid accumulation in Alzheimer's disease transgenic mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-011-0731-5

Early-onset amyloid deposition and cognitive deficits in transgenic mice expressing a double mutant form of amyloid precursor protein 695.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-011-0731-5

Preliminary studies of a novel bifunctional metal chelator targeting Alzheimer's amyloidogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-011-0731-5

Applications of the Morris water maze in the study of learning and memory

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-011-0731-5

Does my mouse have Alzheimer's disease?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-011-0731-5

Dominance of amyloid precursor protein sequence over host cell secretases in determining beta-amyloid profiles studies of interspecies variation and drug action by internally standardized immunoprecipitation/mass spectrometry

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-011-0731-5

Reconstitution of gamma-secretase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-011-0731-5

Long-term effects of melatonin or 17 beta-estradiol on improving spatial memory performance in cognitively impaired, ovariectomized adult rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-011-0731-5

Global prevalence of dementia: a Delphi consensus study

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-011-0731-5

Disease-modifying treatments for Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-011-0731-5

Neuropathology and apolipoprotein E profile of aged chimpanzees: implications for Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-011-0731-5

A beta40 is a major form of beta-amyloid in nonhuman primates.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-011-0731-5

Abeta-peptide length and apolipoprotein E genotype in Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-011-0731-5

beta-Amyloid (A beta) deposition in the brains of aged orangutans.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-011-0731-5

Mouse models of Alzheimer's disease: insight into treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-011-0731-5

Deposition of iron and beta-amyloid plaques is associated with cortical cellular damage in rabbits fed with long-term cholesterol-enriched diets.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-011-0731-5

Intracellular mechanisms of amyloid accumulation and pathogenesis in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-011-0731-5

Common mechanisms of amyloid oligomer pathogenesis in degenerative disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-011-0731-5

Alzheimer's disease: Initial report of the purification and characterization of a novel cerebrovascular amyloid protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-011-0731-5

Presenilins as therapeutic targets for the treatment of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-011-0731-5

Effects of β-amyloid protein on serotoninergic, noradrenergic, and cholinergic markers in neurons of the pontomesencephalic tegmentum in the rat

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-011-0731-5

Animal models of Alzheimer's disease and frontotemporal dementia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-011-0731-5

Compartmentalized tau hyperphosphorylation and increased levels of kinases in transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-011-0731-5

Formation of neurofibrillary tangles in P301l tau transgenic mice induced by Abeta 42 fibrils

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-011-0731-5

Do axonal defects in tau and amyloid precursor protein transgenic animals model axonopathy in Alzheimer's disease?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-011-0731-5

Disruption of axonal transport and neuronal viability by amyloid precursor protein mutations in Drosophila.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-011-0731-5

Intermittent fasting and caloric restriction ameliorate age-related behavioral deficits in the triple-transgenic mouse model of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-011-0731-5

Staging of neurofibrillary degeneration caused by human tau overexpression in a unique cellular model of human tauopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-011-0731-5

Impaired fear conditioning in Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-011-0731-5

Has the amyloid cascade hypothesis for Alzheimer's disease been proved?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-011-0731-5

Alzheimer's disease: the amyloid cascade hypothesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-011-0731-5

The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-011-0731-5

The domestication of social cognition in dogs

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-011-0731-5

Co-localization of beta-amyloid peptides, apolipoprotein E and glial markers in senile plaques in the prefrontal cortex of old rhesus monkeys.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-011-0731-5

Abnormally phosphorylated protein tau in the cortex of aged individuals of various mammalian orders.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-011-0731-5

Concomitant detection of beta-amyloid peptides with N-terminal truncation and different C-terminal endings in cortical plaques from cases with Alzheimer's disease, senile monkeys and triple transgenic mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-011-0731-5

Role of Protein Aggregation in Mitochondrial Dysfunction and Neurodegeneration in Alzheimer's and Parkinson's Diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-011-0731-5

Expression of human apolipoprotein E reduces amyloid-beta deposition in a mouse model of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-011-0731-5

Apolipoprotein E isoform-dependent amyloid deposition and neuritic degeneration in a mouse model of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-011-0731-5

Brain glucose and energy metabolism abnormalities in sporadic Alzheimer disease. Causes and consequences: an update

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-011-0731-5

Glucose metabolism and insulin receptor signal transduction in Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-011-0731-5

Correlative Memory Deficits, Abeta Elevation, and Amyloid Plaques in Transgenic Mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-011-0731-5

Oral administration of a potent and selective non-peptidic BACE-1 inhibitor decreases beta-cleavage of amyloid precursor protein and amyloid-beta production in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-011-0731-5

Age-progressing cognitive impairments and neuropathology in transgenic CRND8 mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-011-0731-5

Human-like rodent amyloid-beta-peptide determines Alzheimer pathology in aged wild-type Octodon degu

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-011-0731-5

Overexpression of glutaminyl cyclase, the enzyme responsible for pyroglutamate A{beta} formation, induces behavioral deficits, and glutaminyl cyclase knock-out rescues the behavioral phenotype in 5XFAD mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-011-0731-5

Complement mRNA in the mammalian brain: responses to Alzheimer's disease and experimental brain lesioning

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-011-0731-5

Conservation of the sequence of the Alzheimer's disease amyloid peptide in dog, polar bear and five other mammals by cross-species polymerase chain reaction analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-011-0731-5

Long-term potentiation is increased in the CA1 area of the hippocampus of APP(swe/ind) CRND8 mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-011-0731-5

APP processing and synaptic function

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-011-0731-5

Comparable amyloid beta-protein (A beta) 42(43) and A beta 40 deposition in the aged monkey brain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-011-0731-5

Progressive age-related impairment of cognitive behavior in APP23 transgenic mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-011-0731-5

SIRT1 deacetylase protects against neurodegeneration in models for Alzheimer's disease and amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-011-0731-5

Neurodegeneration and defective neurotransmission in a Caenorhabditis elegans model of tauopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-011-0731-5

Active immunization trial in Abeta42-injected P301L tau transgenic mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-011-0731-5

Emotion circuits in the brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-011-0731-5

Neurofibrillary tangles, amyotrophy and progressive motor disturbance in mice expressing mutant (P301L) tau protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-011-0731-5

Enhanced neurofibrillary degeneration in transgenic mice expressing mutant tau and APP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-011-0731-5

Simvastatin enhances learning and memory independent of amyloid load in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-011-0731-5

Neuronal cell death in transmissible spongiform encephalopathies (prion diseases) revisited: from apoptosis to autophagy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-011-0731-5

A diet enriched with the omega-3 fatty acid docosahexaenoic acid reduces amyloid burden in an aged Alzheimer mouse model.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-011-0731-5

The molecular bases of Alzheimer's disease and other neurodegenerative disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-011-0731-5

Amyloid precursor protein in aged nonhuman primates

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-011-0731-5

Amyloid plaque core protein in Alzheimer disease and Down syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-011-0731-5

Acetylcholinesterase-rich pyramidal neurons in the human neocortex and hippocampus: absence at birth, development during the life span, and dissolution in Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-011-0731-5

Neurodegenerative stimuli induce persistent ADF/cofilin-actin rods that disrupt distal neurite function

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-011-0731-5

Neuropathology of human Alzheimer disease after immunization with amyloid-beta peptide: a case report.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-011-0731-5

GFAP mRNA increases with age in rat and human brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-011-0731-5

Transcutaneous beta-amyloid immunization reduces cerebral beta-amyloid deposits without T cell infiltration and microhemorrhage

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-011-0731-5

Intraneuronal beta-amyloid aggregates, neurodegeneration, and neuron loss in transgenic mice with five familial Alzheimer's disease mutations: potential factors in amyloid plaque formation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-011-0731-5

Triple-transgenic model of Alzheimer's disease with plaques and tangles: intracellular Abeta and synaptic dysfunction

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-011-0731-5

Chronic administration of pioglitazone attenuates intracerebroventricular streptozotocin induced-memory impairment in rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-011-0731-5

Accelerated extinction of conditioned taste aversion in P301L tau transgenic mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-011-0731-5

Cerebral hemorrhage after passive anti-Abeta immunotherapy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-011-0731-5

Neuronal neprilysin overexpression is associated with attenuation of Abeta-related spatial memory deficit.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-011-0731-5

Aging and time-of-day effects on anxiety in female Octodon degus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-011-0731-5

Cognitive performance and biochemical markers in septum, hippocampus and striatum of rats after an i.c.v. injection of streptozotocin: a correlation analysis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-011-0731-5

Acyl-coenzyme A: cholesterol acyltransferase modulates the generation of the amyloid beta-peptide

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-011-0731-5

Alzheimer's disease: the cholesterol connection

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-011-0731-5

Diffuse beta-amyloid plaques and hyperphosphorylated tau are unrelated processes in aged dogs with behavioral deficits.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-011-0731-5

The excitotoxin quinolinic acid induces tau phosphorylation in human neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-011-0731-5

Individual differences in the cognitive and neurobiological consequences of normal aging

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-011-0731-5

Green tea epigallocatechin-3-gallate (EGCG) modulates amyloid precursor protein cleavage and reduces cerebral amyloidosis in Alzheimer transgenic mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-011-0731-5

Metal-protein attenuation with iodochlorhydroxyquin (clioquinol) targeting Abeta amyloid deposition and toxicity in Alzheimer disease: a pilot phase 2 clinical trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-011-0731-5

Causative and susceptibility genes for Alzheimer's disease: a review.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-011-0731-5

Cerebrolysin decreases amyloid-beta production by regulating amyloid protein precursor maturation in a transgenic model of Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-011-0731-5

Canine counterpart of senile dementia of the Alzheimer type: amyloid plaques near capillaries but lack of spatial relationship with activated microglia and macrophages.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-011-0731-5

Dominant and differential deposition of distinct beta-amyloid peptide species, A beta N3(pE), in senile plaques.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-011-0731-5

Amino- and carboxyl-terminal heterogeneity of beta-amyloid peptides deposited in human brain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-011-0731-5

Alzheimer-like changes in protein kinase B and glycogen synthase kinase-3 in rat frontal cortex and hippocampus after damage to the insulin signalling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-011-0731-5

The canine sand maze: an appetitive spatial memory paradigm sensitive to age-related change in dogs.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-011-0731-5

The canine cognitive dysfunction rating scale (CCDR): a data-driven and ecologically relevant assessment tool

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-011-0731-5

Natural non-trasgenic animal models for research in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-011-0731-5

The progression of beta-amyloid deposition in the frontal cortex of the aged canine

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-011-0731-5

Immunization with amyloid-beta attenuates Alzheimer-disease-like pathology in the PDAPP mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-011-0731-5

A beta immunotherapy: Lessons learned for potential treatment of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-011-0731-5

Amyloid peptides are toxic via a common oxidative mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-011-0731-5

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-011-0731-5

Chronic treatment with trans resveratrol prevents intracerebroventricular streptozotocin induced cognitive impairment and oxidative stress in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-011-0731-5

The effect of aging on pars compacta of the substantia nigra in rhesus monkey.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-011-0731-5

Trace amounts of copper in water induce beta-amyloid plaques and learning deficits in a rabbit model of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-011-0731-5

Body size, energy metabolism and lifespan

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-011-0731-5

Transgenic models of Alzheimer's disease: learning from animals

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-011-0731-5

The physiological link between metabolic rate depression and tau phosphorylation in mammalian hibernation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-011-0731-5

Amyloid precursor protein, presenilins, and alpha-synuclein: molecular pathogenesis and pharmacological applications in Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-011-0731-5

Tau filament formation and associative memory deficit in aged mice expressing mutant (R406W) human tau.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-011-0731-5

Age-dependent cognitive decline in the APP23 model precedes amyloid deposition.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-011-0731-5

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-011-0731-5

Proteolytic mechanisms in amyloid-beta metabolism: therapeutic implications for Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-011-0731-5

Beta-secretase cleavage of Alzheimer's amyloid precursor protein by the transmembrane aspartic protease BACE

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-011-0731-5

Naturally secreted oligomers of amyloid beta protein potently inhibit hippocampal long-term potentiation in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-011-0731-5

Rat models of dementia based on reductions in regional glucose metabolism, cerebral blood flow and cytochrome oxidase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-011-0731-5

Activated actin-depolymerizing factor/cofilin sequesters phosphorylated microtubule-associated protein during the assembly of alzheimer-like neuritic cytoskeletal striations.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-011-0731-5

Intraneuronal APP, not free Aβ peptides in 3xTg-AD mice: implications for tau versus Aβ-mediated Alzheimer neurodegeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-011-0731-5

Neuritic (senile) plaques and filamentous changes in aged rhesus monkeys

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-011-0731-5

Chronic treatment with the gamma-secretase inhibitor LY-411,575 inhibits beta-amyloid peptide production and alters lymphopoiesis and intestinal cell differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-011-0731-5

Short-term synaptic plasticity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-011-0731-5

Neuron loss in APP transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-011-0731-5

Unexpected magnetism in a dielectric oxide

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00702-011-0731-5

Familial influence on plaque formation in the beagle brain

21 January 2018

1 reference

12 December 2020

Expressions of Abeta1-40, Abeta1-42, tau202, tau396 and tau404 after intracerebroventricular injection of streptozotocin in rats

1 reference

12 December 2020

Apolipoprotein E4 and beta amyloid in senile plaques and cerebral blood vessels of aged rhesus monkeys.

1 reference

12 December 2020

Trace copper levels in the drinking water, but not zinc or aluminum influence CNS Alzheimer-like pathology

1 reference

12 December 2020

Early changes in neurons of the hippocampus and neocortex in transgenic rats expressing intracellular human a-beta.

1 reference

12 December 2020

Homology of the amyloid beta protein precursor in monkey and human supports a primate model for beta amyloidosis in Alzheimer's disease.

1 reference

12 December 2020

Reversible paired helical filament-like phosphorylation of tau is an adaptive process associated with neuronal plasticity in hibernating animals.

1 reference

12 December 2020

The pathology of APP transgenic mice: a model of Alzheimer's disease or simply overexpression of APP?

1 reference

12 December 2020

General and dramatic glial reaction in Alzheimer brains

1 reference

12 December 2020

PS2APP transgenic mice, coexpressing hPS2mut and hAPPswe, show age-related cognitive deficits associated with discrete brain amyloid deposition and inflammation.

1 reference

12 December 2020

Regional changes of monoamines in cerebral cortex and subcortical structures of aging rhesus monkeys

1 reference

12 December 2020

Nonhuman primates as models for aging and Alzheimer's disease

1 reference

12 December 2020

Transgenic animal models of Alzheimer's disease and related disorders: histopathology, behavior and therapy.

1 reference

12 December 2020

Animal models of cerebral beta-amyloid angiopathy

1 reference

12 December 2020

A rabbit model of Alzheimer's disease: valid at neuropathological, cognitive, and therapeutic levels

1 reference

12 December 2020

Transgenic mouse models of Alzheimer's disease: phenotype and application

1 reference

12 December 2020

α1-Antichymotrypsin is present together with the β-protein in monkey brain amyloid deposits

1 reference

12 December 2020

Tau protein isoforms, phosphorylation and role in neurodegenerative disorders11These authors contributed equally to this work

1 reference

12 December 2020

Observation of metastable Abeta amyloid protofibrils by atomic force microscopy

1 reference

12 December 2020

Neurodegeneration with tau accumulation in a transgenic mouse expressing V337M human tau.

1 reference

12 December 2020

Pathways towards and away from Alzheimer's disease

1 reference

12 December 2020

Temporal and spatial relationship between the death of PrP-damaged neurones and microglial activation

1 reference

12 December 2020

Brain insulin system dysfunction in streptozotocin intracerebroventricularly treated rats generates hyperphosphorylated tau protein.

1 reference

12 December 2020

Review of insulin and insulin-like growth factor expression, signaling, and malfunction in the central nervous system: relevance to Alzheimer's disease.

1 reference

12 December 2020

[Animal models of Alzheimer's disease: a road full of pitfalls].

1 reference

12 December 2020

Carboxyl end-specific monoclonal antibodies to amyloid beta protein (A beta) subtypes (A beta 40 and A beta 42(43)) differentiate A beta in senile plaques and amyloid angiopathy in brains of aged cynomolgus monkeys

1 reference

12 December 2020

Filamentous tau pathology in nerve cells, astrocytes, and oligodendrocytes of aged baboons

1 reference

12 December 2020

Expansion of the Golgi apparatus in rat cerebral cortex following intracerebroventricular injections of streptozotocin.

1 reference

12 December 2020

Reduction of amyloid load and cerebral damage in a transgenic mouse model of Alzheimer's disease by treatment with a beta-sheet breaker peptide.

1 reference

12 December 2020

Discovery of (S)-2-((S)-2-(3,5-difluorophenyl)-2-hydroxyacetamido)-N-((S,Z)-3-methyl-4-oxo-4,5-dihydro-3H-benzo[d][1,2]diazepin-5-yl)propanamide (BMS-433796): a gamma-secretase inhibitor with Abeta lowering activity in a transgenic mouse model of Al

1 reference

12 December 2020

Interaction of tau isoforms with Alzheimer's disease abnormally hyperphosphorylated tau and in vitro phosphorylation into the disease-like protein

1 reference

12 December 2020

Abnormal neuronal and glial argyrophilic fibrillary structures in the brain of an aged albino cynomolgus monkey (Macaca fascicularis)

1 reference

12 December 2020

10.1007/S00702-011-0731-5

Identifiers

DOI

1 reference

25 August 2017

1 reference