(Q38180665)

30 August 2017

title

TP53 mutants in the tower of babel of cancer progression (English)

1 reference

30 August 2017

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24449472%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

Yari Ciribilli

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24449472%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

Gilberto Fronza

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24449472%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

Paola Monti

series ordinal

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24449472%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

4

Alberto Inga

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24449472%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

publication date

14 March 2014

1 reference

30 August 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24449472%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

volume

35

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24449472%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

issue

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24449472%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

page(s)

689-701

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24449472%20AND%20SRC:MED&resulttype=core&format=json

A Mutant-p53/Smad complex opposes p63 to empower TGFbeta-induced metastasis

1 June 2020

cites work

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22514

p53 polymorphism influences response in cancer chemotherapy via modulation of p73-dependent apoptosis

21 January 2018

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https://api.crossref.org/works/10.1002%2FHUMU.22514

Genetic selection of intragenic suppressor mutations that reverse the effect of common p53 cancer mutations

21 January 2018

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Preferential binding of hot spot mutant p53 proteins to supercoiled DNA in vitro and in cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22514

Expression of galectin-7 is induced in breast cancer cells by mutant p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22514

p53 mutants without a functional tetramerisation domain are not oncogenic

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22514

Modulation of activity of the promoter of the human MDR1 gene by Ras and p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22514

Crystal structure of a p53 tumor suppressor-DNA complex: understanding tumorigenic mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22514

The coordinated p53 and estrogen receptor cis-regulation at an FLT1 promoter SNP is specific to genotoxic stress and estrogenic compound

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22514

Transactivation specificity is conserved among p53 family proteins and depends on a response element sequence code

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22514

Mutant p53 interactome identifies nardilysin as a p53R273H-specific binding partner that promotes invasion

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22514

p73 and p63 are homotetramers capable of weak heterotypic interactions with each other but not with p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22514

Targeted point mutations of p53 lead to dominant-negative inhibition of wild-type p53 function

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22514

Gain of function of mutant p53: the mutant p53/NF-Y protein complex reveals an aberrant transcriptional mechanism of cell cycle regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22514

Gain of function mutations in p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22514

Mutant p53 cooperates with ETS2 to promote etoposide resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22514

Insights into wild-type and mutant p53 functions provided by genetically engineered mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22514

Mutant p53 gain-of-function induces epithelial-mesenchymal transition through modulation of the miR-130b-ZEB1 axis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22514

Oncogenomic Approaches in Exploring Gain of Function of Mutant p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22514

MicroRNA-128-2 targets the transcriptional repressor E2F5 enhancing mutant p53 gain of function

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22514

p63 and p73, the ancestors of p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22514

Definition of a consensus binding site for p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22514

Structure of p73 DNA-binding domain tetramer modulates p73 transactivation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22514

Id2 gene is a transcriptional target of the protein complex mutant p53/E2F1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22514

The execution of the transcriptional axis mutant p53, E2F1 and ID4 promotes tumor neo-angiogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22514

Activation of c-myc gene expression by tumor-derived p53 mutants requires a discrete C-terminal domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22514

Mutant p53 disrupts mammary tissue architecture via the mevalonate pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22514

Mutant p53: one name, many proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22514

Regulation of mutant p53 temperature-sensitive DNA binding.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22514

A subset of tumor-derived mutant forms of p53 down-regulate p63 and p73 through a direct interaction with the p53 core domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22514

More targets, more pathways and more clues for mutant p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22514

A Pin1/mutant p53 axis promotes aggressiveness in breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22514

The role of mutant p53 in human cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22514

p53, a novel regulator of lipid metabolism pathways.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22514

Cytoplasmic functions of the tumour suppressor p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22514

Transcription factor NF-Y induces apoptosis in cells expressing wild-type p53 through E2F1 upregulation and p53 activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22514

Two hot spot mutant p53 mouse models display differential gain of function in tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22514

Presence of dominant negative mutation of TP53 is a risk of early recurrence in oral cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22514

Promyelocytic leukemia protein is required for gain of function by mutant p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22514

A microRNA component of the p53 tumour suppressor network

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22514

Does TP53 mutation promote ovarian cancer metastasis to omentum by regulating lipid metabolism?

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22514

XIAP inhibits autophagy via XIAP-Mdm2-p53 signalling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22514

Phospho-ΔNp63α is a key regulator of the cisplatin-induced microRNAome in cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22514

p53 mutants exhibiting enhanced transcriptional activation and altered promoter selectivity are revealed using a sensitive, yeast-based functional assay

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22514

Novel human p53 mutations that are toxic to yeast can enhance transactivation of specific promoters and reactivate tumor p53 mutants

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22514

Structural evolution of p53, p63, and p73: Implication for heterotetramer formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22514

MicroRNAs, wild-type and mutant p53: more questions than answers

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22514

Altered-function p53 missense mutations identified in breast cancers can have subtle effects on transactivation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22514

Noncanonical DNA motifs as transactivation targets by wild type and mutant p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22514

Monoallelically expressed gene related to p53 at 1p36, a region frequently deleted in neuroblastoma and other human cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22514

Mutant p53R273H attenuates the expression of phase 2 detoxifying enzymes and promotes the survival of cells with high levels of reactive oxygen species

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22514

Understanding the function-structure and function-mutation relationships of p53 tumor suppressor protein by high-resolution missense mutation analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22514

The complex interactions of p53 with target DNA: we learn as we go.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22514

Structural basis of DNA recognition by p53 tetramers.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22514

Diversity in DNA recognition by p53 revealed by crystal structures with Hoogsteen base pairs

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22514

An integrative genomic approach identifies p73 and p63 as activators of miR-200 microRNA family transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22514

Mutant p53(R175H) upregulates Twist1 expression and promotes epithelial-mesenchymal transition in immortalized prostate cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22514

Mechanisms of differential activation of target gene promoters by p53 hinge domain mutants with impaired apoptotic function

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22514

p53 Research: the past thirty years and the next thirty years.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22514

Gain of function of a p53 hot spot mutation in a mouse model of Li-Fraumeni syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22514

Sequence-dependent sliding kinetics of p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22514

The TP53 website: an integrative resource centre for the TP53 mutation database and TP53 mutant analysis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22514

Tumor suppression in the absence of p53-mediated cell-cycle arrest, apoptosis, and senescence

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22514

PTEN has tumor-promoting properties in the setting of gain-of-function p53 mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22514

A common gain of function of p53 cancer mutants in inducing genetic instability

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22514

TopBP1 mediates mutant p53 gain of function through NF-Y and p63/p73.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22514

Small molecule induced reactivation of mutant p53 in cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22514

Mouse models of p53 functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22514

Differential activation of target cellular promoters by p53 mutants with impaired apoptotic function

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22514

Increased oxidative damage in carriers of the germline TP53 p.R337H mutation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22514

Mutant p53 attenuates the anti-tumorigenic activity of fibroblasts-secreted interferon beta

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22514

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22514

p63 is a suppressor of tumorigenesis and metastasis interacting with mutant p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22514

The biological impact of the human master regulator p53 can be altered by mutations that change the spectrum and expression of its target genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22514

The expanding universe of p53 targets

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22514

Estrogen receptor acting in cis enhances WT and mutant p53 transactivation at canonical and noncanonical p53 target sequences

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22514

A single-nucleotide polymorphism in a half-binding site creates p53 and estrogen receptor control of vascular endothelial growth factor receptor 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22514

Diverse stresses dramatically alter genome-wide p53 binding and transactivation landscape in human cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22514

An expression signature for p53 status in human breast cancer predicts mutation status, transcriptional effects, and patient survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22514

SHARP1 suppresses breast cancer metastasis by promoting degradation of hypoxia-inducible factors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22514

Tumour p53 mutations exhibit promoter selective dominance over wild type p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22514

Transcriptional functionality of germ line p53 mutants influences cancer phenotype.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22514

Dominant-negative features of mutant TP53 in germline carriers have limited impact on cancer outcomes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22514

Mutant p53 drives invasion by promoting integrin recycling

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22514

Mutant p53 enhances MET trafficking and signalling to drive cell scattering and invasion

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22514

p53 and its mutants in tumor cell migration and invasion

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22514

Ultraslow oligomerization equilibria of p53 and its implications

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22514

Mutant p53 drives invasion in breast tumors through up-regulation of miR-155.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22514

Mutant p53 uses p63 as a molecular chaperone to alter gene expression and induce a pro-invasive secretome

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22514

Mutant TP53 posttranslational modifications: challenges and opportunities.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22514

Biogenesis of p53 involves cotranslational dimerization of monomers and posttranslational dimerization of dimers. Implications on the dominant negative effect

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22514

Insights into p53 transcriptional function via genome-wide chromatin occupancy and gene expression analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22514

Mutant p53 drives multinucleation and invasion through a process that is suppressed by ANKRD11.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22514

The clinical value of somatic TP53 gene mutations in 1,794 patients with breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22514

Mutant p53 gain-of-function in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22514

Li Fraumeni syndrome, cancer and senescence: a new hypothesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22514

Restoration of DNA-binding and growth-suppressive activity of mutant forms of p53 via a PCAF-mediated acetylation pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22514

Impact of mutant p53 functional properties on TP53 mutation patterns and tumor phenotype: lessons from recent developments in the IARC TP53 database

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22514

Mutant p53 is a transcriptional co-factor that binds to G-rich regulatory regions of active genes and generates transcriptional plasticity

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22514

The p53 network: cellular and systemic DNA damage responses in aging and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22514

Functional mutants of the sequence-specific transcription factor p53 and implications for master genes of diversity

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22514

Transcriptional control of human p53-regulated genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22514

Clinical outcomes and correlates of TP53 mutations and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22514

Increased apoptosis induction by 121F mutant p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22514

DNA binding cooperativity of p53 modulates the decision between cell-cycle arrest and apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22514

Cross talk between stimulated NF-kappaB and the tumor suppressor p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22514

Tumor-derived p53 mutants induce NF-kappaB2 gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22514

Modulation of gene expression by tumor-derived p53 mutants

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22514

Quaternary structure of p53: the light at the end of the tunnel

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22514

Isolation of Temperature-sensitive p53 Mutations from a Comprehensive Missense Mutation Library

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22514

Excessive genomic DNA copy number variation in the Li-Fraumeni cancer predisposition syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22514

Expanding the prion concept to cancer biology: dominant-negative effect of aggregates of mutant p53 tumour suppressor

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22514

Various p53 mutant proteins differently regulate the Ras circuit to induce a cancer-related gene signature

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22514

p53 gain-of-function cancer mutants induce genetic instability by inactivating ATM.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22514

Locus-specific databases in cancer: what future in a post-genomic era? The TP53 LSDB paradigm

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22514

TP53 mutations in human cancer: database reassessment and prospects for the next decade

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22514

Modulation of the vitamin D3 response by cancer-associated mutant p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22514

TAp63 suppresses metastasis through coordinate regulation of Dicer and miRNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22514

Younger age of cancer initiation is associated with shorter telomere length in Li-Fraumeni syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22514

The inherent instability of mutant p53 is alleviated by Mdm2 or p16INK4a loss

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22514

Loss of p63 and its microRNA-205 target results in enhanced cell migration and metastasis in prostate cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22514

Mutant p53 oncogenic functions are sustained by Plk2 kinase through an autoregulatory feedback loop.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22514

Gain-of-Function Activity of Mutant p53 in Lung Cancer through Up-Regulation of Receptor Protein Tyrosine Kinase Axl

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22514

The rebel angel: mutant p53 as the driving oncogene in breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22514

p53 increases MHC class I expression by upregulating the endoplasmic reticulum aminopeptidase ERAP1

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22514

Increased oxidative metabolism in the Li-Fraumeni syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22514

p53 controls cancer cell invasion by inducing the MDM2-mediated degradation of Slug

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22514

Mutant p53-R273H gains new function in sustained activation of EGFR signaling via suppressing miR-27a expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22514

Transactivation of the EGR1 gene contributes to mutant p53 gain of function

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22514

Molecular mechanism of mutant p53 stabilization: the role of HSP70 and MDM2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22514

Specific interaction of mutant p53 with regions of matrix attachment region DNA elements (MARs) with a high potential for base-unpairing

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22514

Mutant p53 exerts a dominant negative effect by preventing wild-type p53 from binding to the promoter of its target genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22514

Periostin cooperates with mutant p53 to mediate invasion through the induction of STAT1 signaling in the esophageal tumor microenvironment

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22514

Characterization of functional domains necessary for mutant p53 gain of function

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22514

Suppression of inhibitor of differentiation 2, a target of mutant p53, is required for gain-of-function mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22514

p63, a p53 homolog at 3q27-29, encodes multiple products with transactivating, death-inducing, and dominant-negative activities

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22514

Gain-of-function mutant p53 upregulates CXC chemokines and enhances cell migration.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22514

Gain of function of mutant p53 by coaggregation with multiple tumor suppressors

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22514

Characterization of the p53 mutants ability to inhibit p73β transactivation using a yeast-based functional assay

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22514

Mutant p53 gain of function: reduction of tumor malignancy of human cancer cell lines through abrogation of mutant p53 expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22514

7 January 2021

When mutants gain new powers: news from the mutant p53 field.

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22514

7 January 2021

p53 mutants can often transactivate promoters containing a p21 but not Bax or PIG3 responsive elements

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22514

7 January 2021

p73 function is inhibited by tumor-derived p53 mutants in mammalian cells.

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22514

7 January 2021

Transactivation and reactivation capabilities of temperature-dependent p53 mutants in yeast and human cells

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22514

7 January 2021

Mutant p53 gain of function in two mouse models of Li-Fraumeni syndrome

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22514

7 January 2021

Telomere length in peripheral blood cells of germline TP53 mutation carriers is shorter than that of normal individuals of corresponding age

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22514

7 January 2021

Induction of apoptosis by cytoplasmically localized wild-type p53 and the S121F mutant super p53

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22514

7 January 2021

Drastic effect of germline TP53 missense mutations in Li-Fraumeni patients

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22514

7 January 2021

A temperature-sensitive mutant of human p53.

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22514

7 January 2021