(Q38543419)

4 September 2017

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title

Lipids in Amyloid-β Processing, Aggregation, and Toxicity (English)

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4 September 2017

1

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author name string

Megan Garvey

series ordinal

2

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4 September 2017

language of work or name

English

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publication date

1 January 2015

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Advances in Experimental Medicine and Biology

4 September 2017

published in

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4 September 2017

volume

855

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4 September 2017

page(s)

67-94

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Comparison of the stabilities and unfolding pathways of human apolipoprotein E isoforms by differential scanning calorimetry and circular dichroism.

4 September 2017

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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A cell surface receptor complex for fibrillar beta-amyloid mediates microglial activation.

31 March 2020

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The Amyloid Precursor Protein Has a Flexible Transmembrane Domain and Binds Cholesterol

31 March 2020

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Abeta40, either soluble or aggregated, is a remarkably potent antioxidant in cell-free oxidative systems

31 March 2020

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Human amyloid-beta synthesis and clearance rates as measured in cerebrospinal fluid in vivo

31 March 2020

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Structural studies of the transmembrane C-terminal domain of the amyloid precursor protein (APP): does APP function as a cholesterol sensor?

31 March 2020

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Transport pathways for clearance of human Alzheimer's amyloid beta-peptide and apolipoproteins E and J in the mouse central nervous system

31 March 2020

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Conversion of non-fibrillar beta-sheet oligomers into amyloid fibrils in Alzheimer's disease amyloid peptide aggregation

31 March 2020

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Cholesterol modulates alpha-secretase cleavage of amyloid precursor protein

31 March 2020

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Misfolding of amyloidogenic proteins at membrane surfaces: the impact of macromolecular crowding.

31 March 2020

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Two types of Alzheimer's beta-amyloid (1-40) peptide membrane interactions: aggregation preventing transmembrane anchoring versus accelerated surface fibril formation.

31 March 2020

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Molecular genetics of Alzheimer's disease: an update

31 March 2020

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Structure and function of sphingolipid- and cholesterol-rich membrane rafts

31 March 2020

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Amyloid Aggregation: Role of Biological Membranes and the Aggregate-Membrane System.

31 March 2020

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Amyloidogenic protein-membrane interactions: mechanistic insight from model systems

31 March 2020

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Disordered proteins: biological membranes as two-dimensional aggregation matrices.

31 March 2020

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https://api.crossref.org/works/10.1007%2F978-3-319-17344-3_3

Human apoE isoforms differentially regulate brain amyloid-β peptide clearance

31 March 2020

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Insights into the molecular basis of the differing susceptibility of varying cell types to the toxicity of amyloid aggregates.

31 March 2020

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Apolipoprotein E: a major piece in the Alzheimer's disease puzzle.

31 March 2020

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Membrane dynamics, cholesterol homeostasis, and Alzheimer's disease

31 March 2020

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Interaction of amyloid beta-protein with anionic phospholipids: possible involvement of Lys28 and C-terminus aliphatic amino acids.

31 March 2020

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Topology of human apolipoprotein E3 uniquely regulates its diverse biological functions

31 March 2020

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Lipid membrane templates the ordering and induces the fibrillogenesis of Alzheimer's disease amyloid-beta peptide

31 March 2020

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The interaction between Alzheimer amyloid beta(1-40) peptide and ganglioside GM1-containing membranes

31 March 2020

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Acceleration of amyloid fibril formation by specific binding of Abeta-(1-40) peptide to ganglioside-containing membrane vesicles

31 March 2020

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https://api.crossref.org/works/10.1007%2F978-3-319-17344-3_3

Natural oligomers of the amyloid-beta protein specifically disrupt cognitive function

31 March 2020

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https://api.crossref.org/works/10.1007%2F978-3-319-17344-3_3

Proliferation of amyloid-β42 aggregates occurs through a secondary nucleation mechanism

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-17344-3_3

Influence of lipoproteins on microglial degradation of Alzheimer's amyloid beta-protein

31 March 2020

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Solution structure of amyloid beta-peptide(1-40) in a water-micelle environment. Is the membrane-spanning domain where we think it is?

31 March 2020

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APOE2 enhances neuroprotection against Alzheimer's disease through multiple molecular mechanisms.

31 March 2020

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Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families

31 March 2020

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Molecular genetics of Alzheimer's disease

31 March 2020

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Involvement of oxidative stress-induced abnormalities in ceramide and cholesterol metabolism in brain aging and Alzheimer's disease

31 March 2020

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DHPC strongly affects the structure and oligomerization propensity of Alzheimer's Aβ(1-40) peptide

31 March 2020

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Interaction between amyloid-beta (1-42) peptide and phospholipid bilayers: a molecular dynamics study

31 March 2020

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Structure of the amyloid-beta (1-42) monomer absorbed to model phospholipid bilayers: a molecular dynamics study

31 March 2020

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β-Sheet Structured β-Amyloid(1-40) Perturbs Phosphatidylcholine Model Membranes

31 March 2020

1 reference

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LRP/amyloid beta-peptide interaction mediates differential brain efflux of Abeta isoforms.

31 March 2020

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apoE isoform-specific disruption of amyloid beta peptide clearance from mouse brain

31 March 2020

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Calcium dysregulation and membrane disruption as a ubiquitous neurotoxic mechanism of soluble amyloid oligomers

31 March 2020

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Different conformations of amyloid beta induce neurotoxicity by distinct mechanisms in human cortical neurons.

31 March 2020

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Interaction of Alzheimer's β-amyloid peptides with cholesterol: mechanistic insights into amyloid pore formation

31 March 2020

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Mechanism of cholesterol-assisted oligomeric channel formation by a short Alzheimer β-amyloid peptide

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-17344-3_3

Protein folding and misfolding

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-17344-3_3

A phase 3 trial of semagacestat for treatment of Alzheimer's disease

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-17344-3_3

How to determine the size of folding nuclei of protofibrils from the concentration dependence of the rate and lag-time of aggregation. I. Modeling the amyloid protofibril formation.

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-17344-3_3

Cholesterol modulates the membrane-disordering effects of beta-amyloid peptides in the hippocampus: specific changes in Alzheimer's disease.

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-17344-3_3

Lipid membranes and beta-amyloid: a harmful connection

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-17344-3_3

NSAIDs and enantiomers of flurbiprofen target gamma-secretase and lower Abeta 42 in vivo

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-17344-3_3

Alzheimer's disease amyloid propagation by a template-dependent dock-lock mechanism

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-17344-3_3

Lipid rafts: structure, function and role in HIV, Alzheimer's and prion diseases

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-17344-3_3

Bexarotene blocks calcium-permeable ion channels formed by neurotoxic Alzheimer's β-amyloid peptides.

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-17344-3_3

Simvastatin strongly reduces levels of Alzheimer's disease beta -amyloid peptides Abeta 42 and Abeta 40 in vitro and in vivo

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-17344-3_3

Kinetic studies of amyloid beta-protein fibril assembly. Differential effects of alpha-helix stabilization

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-17344-3_3

A de novo designed helix-turn-helix peptide forms nontoxic amyloid fibrils

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-17344-3_3

Lipids in Alzheimer's disease: A century-old story

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-17344-3_3

The role of cholesterol in the biosynthesis of beta-amyloid

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-17344-3_3

Phosphate and HEPES buffers potently affect the fibrillation and oligomerization mechanism of Alzheimer's Aβ peptide

31 March 2020

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Amyloidosis and Alzheimer's disease

31 March 2020

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The role of amyloid β in the pathogenesis of Alzheimer's disease

31 March 2020

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Cholesterol modulation as an emerging strategy for the treatment of Alzheimer's disease.

31 March 2020

1 reference

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Targeting Abeta and tau in Alzheimer's disease, an early interim report

31 March 2020

1 reference

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Aggregation state-dependent binding of beta-amyloid peptide to protein and lipid components of rat cortical homogenates.

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-17344-3_3

Human apoE targeted replacement mouse lines: h-apoE4 and h-apoE3 mice differ on spatial memory performance and avoidance behavior.

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-17344-3_3

Soluble protein oligomers in neurodegeneration: lessons from the Alzheimer's amyloid beta-peptide

31 March 2020

1 reference

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Targeting of cell-surface beta-amyloid precursor protein to lysosomes: alternative processing into amyloid-bearing fragments.

31 March 2020

1 reference

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Alzheimer's disease: the amyloid cascade hypothesis

31 March 2020

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The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics

31 March 2020

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Models of amyloid seeding in Alzheimer's disease and scrapie: mechanistic truths and physiological consequences of the time-dependent solubility of amyloid proteins

31 March 2020

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Alzheimer's disease: the lipid connection

31 March 2020

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Apolipoprotein E structure: insights into function.

31 March 2020

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Impact of apolipoprotein E on Alzheimer's disease

31 March 2020

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A seed for Alzheimer amyloid in the brain.

31 March 2020

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Role of apoe/Abeta interactions in the pathogenesis of Alzheimer's disease and cerebral amyloid angiopathy

31 March 2020

1 reference

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Apolipoprotein E isoform-dependent amyloid deposition and neuritic degeneration in a mouse model of Alzheimer's disease

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-17344-3_3

Soluble Aβ oligomers are rapidly sequestered from brain ISF in vivo and bind GM1 ganglioside on cellular membranes

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-17344-3_3

The role of proteolysis in Alzheimer's disease

31 March 2020

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Solution NMR studies of the A beta(1-40) and A beta(1-42) peptides establish that the Met35 oxidation state affects the mechanism of amyloid formation

31 March 2020

1 reference

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Amyloid beta-protein stimulates trafficking of cholesterol and caveolin-1 from the plasma membrane to the Golgi complex in mouse primary astrocytes

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-17344-3_3

Truncated beta-amyloid peptide channels provide an alternative mechanism for Alzheimer's Disease and Down syndrome

31 March 2020

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Disordered amyloidogenic peptides may insert into the membrane and assemble into common cyclic structural motifs

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-17344-3_3

Cholesterol-dependent formation of GM1 ganglioside-bound amyloid beta-protein, an endogenous seed for Alzheimer amyloid

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-17344-3_3

Interactions of amyloid beta-protein with various gangliosides in raft-like membranes: importance of GM1 ganglioside-bound form as an endogenous seed for Alzheimer amyloid

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-17344-3_3

The amyloid cascade hypothesis for Alzheimer's disease: an appraisal for the development of therapeutics

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-17344-3_3

Bicuculline induces synapse formation on primary cultured accessory olfactory bulb neurons

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-17344-3_3

Common structure of soluble amyloid oligomers implies common mechanism of pathogenesis

31 March 2020

1 reference

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Permeabilization of lipid bilayers is a common conformation-dependent activity of soluble amyloid oligomers in protein misfolding diseases

31 March 2020

1 reference

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Annular protofibrils are a structurally and functionally distinct type of amyloid oligomer

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-17344-3_3

Bioinorganic chemistry of Alzheimer's disease

31 March 2020

1 reference

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Transmembrane glycine zippers: physiological and pathological roles in membrane proteins

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-17344-3_3

The role of apolipoprotein E in Alzheimer's disease

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-17344-3_3

Midlife vascular risk factors and Alzheimer's disease in later life: longitudinal, population based study

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-17344-3_3

Effect of different salt ions on the propensity of aggregation and on the structure of Alzheimer's abeta(1-40) amyloid fibrils.

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-17344-3_3

Apolipoprotein E promotes astrocyte colocalization and degradation of deposited amyloid-beta peptides

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-17344-3_3

ApoE isoform-dependent changes in hippocampal synaptic function

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-17344-3_3

Kinetics of adsorption of beta-amyloid peptide Abeta(1-40) to lipid bilayers.

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-17344-3_3

Correlation of beta-amyloid aggregate size and hydrophobicity with decreased bilayer fluidity of model membranes

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-17344-3_3

Profile of changes in lipid bilayer structure caused by beta-amyloid peptide

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-17344-3_3

The structure and function of Alzheimer's gamma secretase enzyme complex.

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-17344-3_3

Substrate-targeting gamma-secretase modulators

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-17344-3_3

Lysine 624 of the amyloid precursor protein (APP) is a critical determinant of amyloid β peptide length: support for a sequential model of γ-secretase intramembrane proteolysis and regulation by the amyloid β precursor protein (APP) juxtamembrane re

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-17344-3_3

Elevated low-density lipoprotein in Alzheimer's disease correlates with brain abeta 1-42 levels.

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-17344-3_3

A Oligomer-Induced Aberrations in Synapse Composition, Shape, and Density Provide a Molecular Basis for Loss of Connectivity in Alzheimer's Disease

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-17344-3_3

Amyloid beta ion channel: 3D structure and relevance to amyloid channel paradigm

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-17344-3_3

Perspectives on future Alzheimer therapies: amyloid-β protofibrils - a new target for immunotherapy with BAN2401 in Alzheimer's disease

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-17344-3_3

Neurodegenerative disease: amyloid pores from pathogenic mutations.

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-17344-3_3

A detergent-insoluble membrane compartment contains A beta in vivo

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-17344-3_3

Differential functions of members of the low density lipoprotein receptor family suggested by their distinct endocytosis rates

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-17344-3_3

Amyloid beta protein forms ion channels: implications for Alzheimer's disease pathophysiology

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-17344-3_3

3D structure of Alzheimer's amyloid-beta(1-42) fibrils

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-17344-3_3

Apolipoprotein E: cholesterol transport protein with expanding role in cell biology

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-17344-3_3

Apolipoprotein E4: a causative factor and therapeutic target in neuropathology, including Alzheimer's disease

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-17344-3_3

Adsorption of Amyloid β (1-40) Peptide at Phospholipid Monolayers

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-17344-3_3

Alzheimer's disease: NMR studies of asialo (GM1) and trisialo (GT1b) ganglioside interactions with Abeta(1-40) peptide in a membrane mimic environment

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-17344-3_3

Lipids revert inert Abeta amyloid fibrils to neurotoxic protofibrils that affect learning in mice

31 March 2020

1 reference

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Alzheimer's disease amyloid beta peptide 25-35 is localized in the membrane hydrocarbon core: x-ray diffraction analysis

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-17344-3_3

Distribution and fluidizing action of soluble and aggregated amyloid beta-peptide in rat synaptic plasma membranes.

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-17344-3_3

Physicochemical interactions of amyloid beta-peptide with lipid bilayers

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-17344-3_3

Interactions of amyloid beta-peptide (1-40) with ganglioside-containing membranes

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-17344-3_3

Abeta polymerization through interaction with membrane gangliosides.

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-17344-3_3

Cellular actions of beta-amyloid precursor protein and its soluble and fibrillogenic derivatives

31 March 2020

1 reference

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Decreased clearance of CNS beta-amyloid in Alzheimer's disease

31 March 2020

1 reference

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Can statins prevent or help treat Alzheimer's disease?

31 March 2020

1 reference

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Membrane disruption by Alzheimer beta-amyloid peptides mediated through specific binding to either phospholipids or gangliosides. Implications for neurotoxicity.

31 March 2020

1 reference

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Phosphatidylinositol and inositol involvement in Alzheimer amyloid-beta fibril growth and arrest

31 March 2020

1 reference

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Review: modulating factors in amyloid-beta fibril formation

31 March 2020

1 reference

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Abeta(1-40) fibril polymorphism implies diverse interaction patterns in amyloid fibrils.

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-17344-3_3

Differences in nucleation behavior underlie the contrasting aggregation kinetics of the Aβ40 and Aβ42 peptides

31 March 2020

1 reference

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Structures of beta-amyloid peptide 1-40, 1-42, and 1-55-the 672-726 fragment of APP-in a membrane environment with implications for interactions with gamma-secretase

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-17344-3_3

Assembly of Alzheimer's Aβ peptide into nanostructured amyloid fibrils

31 March 2020

1 reference

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Apolipoproteins E and J interfere with amyloid-beta uptake by primary human astrocytes and microglia in vitro

31 March 2020

1 reference

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Effects of beta-amyloid peptides on the fluidity of membranes from frontal and parietal lobes of human brain. High potencies of A beta 1-42 and A beta 1-43.

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-17344-3_3

Kinetics of amyloid formation and membrane interaction with amyloidogenic proteins

31 March 2020

1 reference

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Lipid-induced conformational transition of the amyloid core fragment Abeta(28-35) and its A30G and A30I mutants

31 March 2020

1 reference

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Formation of toxic Abeta(1-40) fibrils on GM1 ganglioside-containing membranes mimicking lipid rafts: polymorphisms in Abeta(1-40) fibrils

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-17344-3_3

Accumulation of amyloid beta-protein in the low-density membrane domain accurately reflects the extent of beta-amyloid deposition in the brain

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-17344-3_3

PEGylated phospholipid nanomicelles interact with beta-amyloid((1-42)) and mitigate its beta-sheet formation, aggregation and neurotoxicity in vitro

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-17344-3_3

Amyloid-beta-induced neuronal dysfunction in Alzheimer's disease: from synapses toward neural networks

31 March 2020

1 reference

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Structural basis for increased toxicity of pathological aβ42:aβ40 ratios in Alzheimer disease

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-17344-3_3

Interpreting the aggregation kinetics of amyloid peptides

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-17344-3_3

The interaction of beta-amyloid protein with cellular membranes stimulates its own production

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-17344-3_3

A structural model for Alzheimer's beta -amyloid fibrils based on experimental constraints from solid state NMR

31 March 2020

1 reference

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Self-propagating, molecular-level polymorphism in Alzheimer's beta-amyloid fibrils

31 March 2020

1 reference

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New insights into the determination of HDL structure by apolipoproteins: Thematic review series: high density lipoprotein structure, function, and metabolism

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-17344-3_3

Apolipoprotein E isoforms and lipoprotein metabolism

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-17344-3_3

A new hypothesis for the mechanism of amyloid toxicity, based on the calcium channel activity of amyloid beta protein (A beta P) in phospholipid bilayer membranes

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-17344-3_3

Sphingolipids and gangliosides of the nervous system in membrane function and dysfunction

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-17344-3_3

Multivariate analyses of amyloid-beta oligomer populations indicate a connection between pore formation and cytotoxicity

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-17344-3_3

Genetic predisposition to increased blood cholesterol and triglyceride lipid levels and risk of Alzheimer disease: a Mendelian randomization analysis

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-17344-3_3

Acyl-coenzyme A: cholesterol acyltransferase modulates the generation of the amyloid beta-peptide

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-17344-3_3

Cholesterol modulates the interaction of beta-amyloid peptide with lipid bilayers

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-17344-3_3

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-17344-3_3

Amyloid ion channels: a common structural link for protein-misfolding disease

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-17344-3_3

Cognitive effects of cell-derived and synthetically derived Aβ oligomers

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-17344-3_3

Hypercholesterolemia accelerates the Alzheimer's amyloid pathology in a transgenic mouse model

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-17344-3_3

Relation of plasma lipids to Alzheimer disease and vascular dementia

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-17344-3_3

The two-fold aspect of the interplay of amyloidogenic proteins with lipid membranes.

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-17344-3_3

Statins and cognitive function: a systematic review

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-17344-3_3

Compartmentalization of beta-secretase (Asp2) into low-buoyant density, noncaveolar lipid rafts

31 March 2020

1 reference

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Use of lipid-lowering agents, indication bias, and the risk of dementia in community-dwelling elderly people.

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-17344-3_3

Morphological and biochemical analyses of amyloid plaque core proteins purified from Alzheimer disease brain tissue.

31 March 2020

1 reference

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Apolipoprotein E alleles as risk factors in Alzheimer's disease

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-17344-3_3

Paired beta-sheet structure of an Abeta(1-40) amyloid fibril revealed by electron microscopy

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-17344-3_3

High cholesterol level is essential for myelin membrane growth

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-17344-3_3

Association of apolipoprotein E allele epsilon 4 with late-onset familial and sporadic Alzheimer's disease

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-17344-3_3

Increased amyloid beta-peptide deposition in cerebral cortex as a consequence of apolipoprotein E genotype in late-onset Alzheimer disease

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-17344-3_3

Isolation and quantification of soluble Alzheimer's beta-peptide from biological fluids

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-17344-3_3

Models of membrane-bound Alzheimer's Abeta peptide assemblies

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-17344-3_3

Clearance of Alzheimer's amyloid-ss(1-40) peptide from brain by LDL receptor-related protein-1 at the blood-brain barrier

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-17344-3_3

Diet-induced hypercholesterolemia enhances brain A beta accumulation in transgenic mice

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-17344-3_3

Functional rafts in cell membranes

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-17344-3_3

Cholesterol depletion inhibits the generation of beta-amyloid in hippocampal neurons

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-17344-3_3

Treatment with simvastatin in normocholesterolemic patients with Alzheimer's disease: A 26-week randomized, placebo-controlled, double-blind trial

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-17344-3_3

The Alzheimer's disease-associated amyloid beta-protein is an antimicrobial peptide

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-17344-3_3

Unfolding the role of protein misfolding in neurodegenerative diseases

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-17344-3_3

Atorvastatin for the treatment of mild to moderate Alzheimer disease: preliminary results.

31 March 2020

1 reference

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Biochemical and biophysical features of both oligomer/fibril and cell membrane in amyloid cytotoxicity.

31 March 2020

1 reference

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Protein aggregation and aggregate toxicity: new insights into protein folding, misfolding diseases and biological evolution

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-17344-3_3

Membrane-Protein Interactions Are Key to Understanding Amyloid Formation

31 March 2020

1 reference

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Apolipoprotein E: high-avidity binding to beta-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-17344-3_3

Toxic fibrillar oligomers of amyloid-β have cross-β structure

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-17344-3_3

Common core structure of amyloid fibrils by synchrotron X-ray diffraction.

31 March 2020

1 reference

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The forgotten APOE allele: a review of the evidence and suggested mechanisms for the protective effect of APOE ɛ2.

31 March 2020

1 reference

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gamma-Secretase: successive tripeptide and tetrapeptide release from the transmembrane domain of beta-carboxyl terminal fragment.

31 March 2020

1 reference

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Interaction with amyloid beta peptide compromises the lipid binding function of apolipoprotein E.

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-17344-3_3

Elucidating amyloid beta-protein folding and assembly: A multidisciplinary approach

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-17344-3_3

Self-association of beta-amyloid peptide (1-40) in solution and binding to lipid membranes.

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-17344-3_3

Interaction of Alzheimer beta-amyloid peptide(1-40) with lipid membranes

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-17344-3_3

Impact of APOE genotype on neuropathologic and neurochemical markers of Alzheimer disease

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-17344-3_3

Alzheimer Aβ peptide interactions with lipid membranes: fibrils, oligomers and polymorphic amyloid channels.

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-17344-3_3

The alpha-to-beta conformational transition of Alzheimer's Abeta-(1-42) peptide in aqueous media is reversible: a step by step conformational analysis suggests the location of beta conformation seeding

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-17344-3_3

Up-and-down topological mode of amyloid beta-peptide lying on hydrophilic/hydrophobic interface of ganglioside clusters

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-17344-3_3

Soluble amyloid beta-oligomers affect dielectric membrane properties by bilayer insertion and domain formation: implications for cell toxicity

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-17344-3_3

Amyloid beta-peptide interactions with neuronal and glial cell plasma membrane: binding sites and implications for Alzheimer's disease

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-17344-3_3

Apolipoprotein E in Alzheimer's disease and other neurological disorders

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-17344-3_3

ApoE influences amyloid-β (Aβ) clearance despite minimal apoE/Aβ association in physiological conditions

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-17344-3_3

Membrane rafts in Alzheimer's disease beta-amyloid production

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-17344-3_3

A partially folded structure of amyloid-beta(1-40) in an aqueous environment

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-17344-3_3

Secondary structure conversions of Alzheimer's Abeta(1-40) peptide induced by membrane-mimicking detergents

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-17344-3_3

GM1 ganglioside-mediated accumulation of amyloid beta-protein on cell membranes

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-17344-3_3

Oligomers on the brain: the emerging role of soluble protein aggregates in neurodegeneration

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-17344-3_3

Naturally secreted oligomers of amyloid beta protein potently inhibit hippocampal long-term potentiation in vivo

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-17344-3_3

Kinetics and thermodynamics of amyloid fibril assembly

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-17344-3_3

Evidence for impaired amyloid β clearance in Alzheimer's disease

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-17344-3_3

Apolipoprotein E in sporadic Alzheimer's disease: allelic variation and receptor interactions

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-17344-3_3

Pyroglutamate amyloid β (Aβ) aggravates behavioral deficits in transgenic amyloid mouse model for Alzheimer disease

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-17344-3_3

Decreased prevalence of Alzheimer disease associated with 3-hydroxy-3-methyglutaryl coenzyme A reductase inhibitors.

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-17344-3_3

Brain membrane cholesterol domains, aging and amyloid beta-peptides

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-17344-3_3

Conformational transition of amyloid beta-peptide

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-17344-3_3

Systematic analysis of nucleation-dependent polymerization reveals new insights into the mechanism of amyloid self-assembly

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-17344-3_3

NMR characterization of the interactions between lyso-GM1 aqueous micelles and amyloid beta

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-17344-3_3

Amyloid beta protein (Abeta) starts to deposit as plasma membrane-bound form in diffuse plaques of brains from hereditary cerebral hemorrhage with amyloidosis-Dutch type, Alzheimer disease and nondemented aged subjects

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-17344-3_3

Assembly of hereditary amyloid beta-protein variants in the presence of favorable gangliosides.

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-17344-3_3

Characterizing the appearance and growth of amyloid plaques in APP/PS1 mice

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-17344-3_3

GM1 ganglioside-bound amyloid beta-protein (A beta): a possible form of preamyloid in Alzheimer's disease.

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-17344-3_3

Amyloid-beta peptide assembly: a critical step in fibrillogenesis and membrane disruption

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-17344-3_3

Cholesterol promotes the interaction of Alzheimer β-amyloid monomer with lipid bilayer.

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-17344-3_3

GM1 ganglioside regulates the proteolysis of amyloid precursor protein

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-17344-3_3

The Alzheimer's peptide a beta adopts a collapsed coil structure in water

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-17344-3_3

The toxicity of amyloid β oligomers

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-17344-3_3

Understanding the association of apolipoprotein E4 with Alzheimer disease: clues from its structure

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-17344-3_3

The blood-brain barrier in health and chronic neurodegenerative disorders

31 March 2020

1 reference

https://api.crossref.org/works/10.1007%2F978-3-319-17344-3_3

10.1007/978-3-319-17344-3_3

31 March 2020

Identifiers

DOI

1 reference

4 September 2017

1 reference