(Q35666695)

9 August 2017

1 reference

title

Modulation and function of caspase pathways in B lymphocytes (English)

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9 August 2017

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Edward A Clark

3

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author name string

Jonathan D Graves

series ordinal

1

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9 August 2017

Andrew Craxton

series ordinal

2

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9 August 2017

publication date

1 February 2004

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9 August 2017

published in

Immunological Reviews

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9 August 2017

volume

197

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9 August 2017

page(s)

129-146

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Genetic control of programmed cell death in the nematode C. elegans.

9 August 2017

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Caspase-10 is an initiator caspase in death receptor signaling

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21 January 2018

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The NOD: a signaling module that regulates apoptosis and host defense against pathogens

21 January 2018

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Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis

21 January 2018

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A combinatorial approach defines specificities of members of the caspase family and granzyme B. Functional relationships established for key mediators of apoptosis

21 January 2018

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Conversion of Bcl-2 to a Bax-like death effector by caspases

21 January 2018

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Modulation of cell death by Bcl-XL through caspase interaction

21 January 2018

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Caspase cleavage enhances the apoptosis-inducing effects of BAD.

21 January 2018

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c-IAP1 is cleaved by caspases to produce a proapoptotic C-terminal fragment

21 January 2018

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Cleavage of human inhibitor of apoptosis protein XIAP results in fragments with distinct specificities for caspases

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2004.0110.X

Caspase-induced inactivation of the anti-apoptotic TRAF1 during Fas ligand-mediated apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2004.0110.X

Three mutations in v-Rel render it resistant to cleavage by cell-death protease caspase-3.

21 January 2018

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Phosphorylation of IkappaB-alpha inhibits its cleavage by caspase CPP32 in vitro

21 January 2018

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Cleavage of p21Cip1/Waf1 and p27Kip1 mediates apoptosis in endothelial cells through activation of Cdk2: role of a caspase cascade

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.0105-2896.2004.0110.X

PITSLRE protein kinase activity is associated with apoptosis

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.0105-2896.2004.0110.X

Interactions between protein kinases and proteases in cellular signaling and regulation

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.0105-2896.2004.0110.X

Both phosphorylation and caspase-mediated cleavage contribute to regulation of the Ste20-like protein kinase Mst1 during CD95/Fas-induced apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2004.0110.X

Cleavage of Fyn and Lyn in their N-terminal unique regions during induction of apoptosis: a new mechanism for Src kinase regulation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2004.0110.X

CD95/Fas induces cleavage of the GrpL/Gads adaptor and desensitization of antigen receptor signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2004.0110.X

Transitional B lymphocyte subsets operate as distinct checkpoints in murine splenic B cell development

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2004.0110.X

Enhanced B cell expansion, survival, and humoral responses by targeting death receptor 6

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2004.0110.X

Activation sensitizes human memory B cells to B-cell receptor-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2004.0110.X

Critical role for mitochondria in B cell receptor-mediated apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2004.0110.X

Involvement of Bik, a proapoptotic member of the Bcl-2 family, in surface IgM-mediated B cell apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2004.0110.X

Implication of calpain in caspase activation during B cell clonal deletion

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2004.0110.X

Rapid B cell apoptosis induced by antigen receptor ligation does not require Fas (CD95/APO-1), the adaptor protein FADD/MORT1 or CrmA-sensitive caspases but is defective in both MRL-+/+ and MRL-lpr/lpr mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2004.0110.X

Death signals from the B cell antigen receptor target mitochondria, activating necrotic and apoptotic death cascades in a murine B cell line, WEHI-231.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2004.0110.X

B cell receptor-stimulated mitochondrial phospholipase A2 activation and resultant disruption of mitochondrial membrane potential correlate with the induction of apoptosis in WEHI-231 B cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2004.0110.X

Mitochondria-dependent caspase-9 activation is necessary for antigen receptor-mediated effector caspase activation and apoptosis in WEHI 231 lymphoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2004.0110.X

Apoptosis initiated by Bcl-2-regulated caspase activation independently of the cytochrome c/Apaf-1/caspase-9 apoptosome

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2004.0110.X

Regulation of cell death: the calcium-apoptosis link

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2004.0110.X

Caspase-independent cell death in T lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2004.0110.X

Caspase-9 and APAF-1 form an active holoenzyme

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2004.0110.X

Apoptosis in the development and maintenance of the immune system

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2004.0110.X

Control of apoptosis in the immune system: Bcl-2, BH3-only proteins and more

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2004.0110.X

IAP proteins: blocking the road to death's door

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2004.0110.X

Attenuation of apoptosis underlies B lymphocyte stimulator enhancement of humoral immune response

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2004.0110.X

BAFF-induced NEMO-independent processing of NF-kappa B2 in maturing B cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2004.0110.X

BAFF/BLyS receptor 3 binds the B cell survival factor BAFF ligand through a discrete surface loop and promotes processing of NF-kappaB2

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2004.0110.X

The biochemistry of apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2004.0110.X

Serine phosphorylation of death agonist BAD in response to survival factor results in binding to 14-3-3 not BCL-X(L)

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2004.0110.X

Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2004.0110.X

Proapoptotic BID is required for myeloid homeostasis and tumor suppression

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2004.0110.X

Proapoptotic Bcl-2 relative Bim required for certain apoptotic responses, leukocyte homeostasis, and to preclude autoimmunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2004.0110.X

Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2004.0110.X

TRAIL causes cleavage of bid by caspase-8 and loss of mitochondrial membrane potential resulting in apoptosis in BJAB cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2004.0110.X

Bad-deficient mice develop diffuse large B cell lymphoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2004.0110.X

A positive regulatory role for Cbl family proteins in tumor necrosis factor-related activation-induced cytokine (trance) and CD40L-mediated Akt activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2004.0110.X

The serine/threonine kinase Pim-2 is a transcriptionally regulated apoptotic inhibitor

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2004.0110.X

CD40 signaling in B cells regulates the expression of the Pim-1 kinase via the NF-kappa B pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2004.0110.X

Bim: a novel member of the Bcl-2 family that promotes apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2004.0110.X

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2004.0110.X

Identification of novel isoforms of the BH3 domain protein Bim which directly activate Bax to trigger apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2004.0110.X

The proapoptotic BH3-only protein bim is expressed in hematopoietic, epithelial, neuronal, and germ cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2004.0110.X

Downregulation of Bim, a proapoptotic relative of Bcl-2, is a pivotal step in cytokine-initiated survival signaling in murine hematopoietic progenitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2004.0110.X

Dominant-negative c-Jun promotes neuronal survival by reducing BIM expression and inhibiting mitochondrial cytochrome c release

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2004.0110.X

JNK phosphorylation of Bim-related members of the Bcl2 family induces Bax-dependent apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2004.0110.X

Activation of the ERK1/2 signaling pathway promotes phosphorylation and proteasome-dependent degradation of the BH3-only protein, Bim.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2004.0110.X

Smad3 potentiates transforming growth factor beta (TGFbeta )-induced apoptosis and expression of the BH3-only protein Bim in WEHI 231 B lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2004.0110.X

Mice transgenic for BAFF develop lymphocytic disorders along with autoimmune manifestations

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2004.0110.X

Phosphorylation of the pro-apoptotic protein Bim in lymphocytes is associated with protection from apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2004.0110.X

Induction of apoptosis by human Nbk/Bik, a BH3-containing protein that interacts with E1B 19K

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2004.0110.X

Phosphorylation of the pro-apoptotic protein BIK: mapping of phosphorylation sites and effect on apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2004.0110.X

Induction of cell death by the BH3-only Bcl-2 homolog Nbk/Bik is mediated by an entirely Bax-dependent mitochondrial pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2004.0110.X

Functional dissection of the pro-apoptotic protein Bik. Heterodimerization with anti-apoptosis proteins is insufficient for induction of cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2004.0110.X

Involvement of stress-activated protein kinase and p38 mitogen-activated protein kinase in mIgM-induced apoptosis of human B lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2004.0110.X

Blk, a BH3-containing mouse protein that interacts with Bcl-2 and Bcl-xL, is a potent death agonist

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2004.0110.X

BAFF-R, a newly identified TNF receptor that specifically interacts with BAFF

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2004.0110.X

Identification of a novel receptor for B lymphocyte stimulator that is mutated in a mouse strain with severe B cell deficiency

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2004.0110.X

CD47 and the 19 kDa Interacting Protein-3 (BNIP3) in T Cell Apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2004.0110.X

Mechanisms of CD47-induced caspase-independent cell death in normal and leukemic cells: link between phosphatidylserine exposure and cytoskeleton organization

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2004.0110.X

Multiple gene duplication and expression of mouse bcl-2-related genes, A1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2004.0110.X

Accelerated neutrophil apoptosis in mice lacking A1-a, a subtype of the bcl-2-related A1 gene.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2004.0110.X

Phospholipase Cgamma2 provides survival signals via Bcl2 and A1 in different subpopulations of B cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2004.0110.X

NF-kappaB-mediated up-regulation of Bcl-x and Bfl-1/A1 is required for CD40 survival signaling in B lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2004.0110.X

Regulation of lymphocyte proliferation and death by FLIP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2004.0110.X

FLICE-inhibitory protein is a key regulator of germinal center B cell apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2004.0110.X

Death-receptor contribution to the germinal-center reaction.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2004.0110.X

NF-kappaB signals induce the expression of c-FLIP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2004.0110.X

The c-IAP-1 and c-IAP-2 proteins are direct inhibitors of specific caspases

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2004.0110.X

Molecular cloning of ILP-2, a novel member of the inhibitor of apoptosis protein family

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2004.0110.X

Regulation of apoptosis: the ubiquitous way

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2004.0110.X

Mammalian mitochondrial IAP binding proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2004.0110.X

The role of interferon regulatory factors in the interferon system and cell growth control

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2004.0110.X

Regulation of lymphocyte apoptosis by interferon regulatory factor 4 (IRF-4)

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2004.0110.X

Gadd45 beta mediates the protective effects of CD40 costimulation against Fas-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2004.0110.X

Lymphoid malignancies: the dark side of B-cell differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2004.0110.X

PED/PEA-15: an anti-apoptotic molecule that regulates FAS/TNFR1-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2004.0110.X

Novel NEMO/IkappaB kinase and NF-kappa B target genes at the pre-B to immature B cell transition

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2004.0110.X

Fas-mediated apoptosis and activation-induced T-cell proliferation are defective in mice lacking FADD/Mort1

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2004.0110.X

A dominant interfering mutant of FADD/MORT1 enhances deletion of autoreactive thymocytes and inhibits proliferation of mature T lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2004.0110.X

Effects of a dominant interfering mutant of FADD on signal transduction in activated T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2004.0110.X

A dominant negative Fas-associated death domain protein mutant inhibits proliferation and leads to impaired calcium mobilization in both T-cells and fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2004.0110.X

Phosphorylation of FADD/ MORT1 at serine 194 and association with a 70-kDa cell cycle-regulated protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2004.0110.X

Cell cycle effects by C-FADD depend on its C-terminal phosphorylation site.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2004.0110.X

The caspase 8 inhibitor c-FLIP(L) modulates T-cell receptor-induced proliferation but not activation-induced cell death of lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2004.0110.X

The caspase-8 inhibitor FLIP promotes activation of NF-kappaB and Erk signaling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2004.0110.X

Early activation of caspases during T lymphocyte stimulation results in selective substrate cleavage in nonapoptotic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2004.0110.X

Caspase activation is required for T cell proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2004.0110.X

A role for FADD in T cell activation and development

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2004.0110.X

Pleiotropic defects in lymphocyte activation caused by caspase-8 mutations lead to human immunodeficiency

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2004.0110.X

Essential role for caspase 8 in T-cell homeostasis and T-cell-mediated immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2004.0110.X

Caspase activity is required for stimulated B lymphocytes to enter the cell cycle

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2004.0110.X

Caspase-3 regulates cell cycle in B cells: a consequence of substrate specificity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2004.0110.X

21 January 2018

Lymphocyte homeostasis

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2004.0110.X

Transcription factor LKLF is sufficient to program T cell quiescence via a c-Myc-dependent pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2004.0110.X

SATB1 targets chromatin remodelling to regulate genes over long distances

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2004.0110.X

SATB1 cleavage by caspase 6 disrupts PDZ domain-mediated dimerization, causing detachment from chromatin early in T-cell apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2004.0110.X

Caspase activation is not death

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2004.0110.X

The CD40-Inducible Bcl-2 Family Member A1 Protects B Cells from Antigen Receptor-Mediated Apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2004.0110.X

Mechanism of antigen-driven selection in germinal centres

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.0105-2896.2004.0110.X

10.1111/J.0105-2896.2004.0110.X

21 January 2018

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DOI

1 reference

9 August 2017

1 reference