(Q37785490)

23 August 2017

title

Harnessing the complexity of DNA-damage response pathways to improve cancer treatment outcomes (English)

1 reference

23 August 2017

0 references

F Al-Ejeh

1

0 references

Sunil R Lakhani

4

object named as

S R Lakhani

1 reference

23 August 2017

R Kumar

2

1 reference

23 August 2017

A Wiegmans

3

1 reference

23 August 2017

M P Brown

5

1 reference

23 August 2017

K K Khanna

6

1 reference

23 August 2017

language of work or name

English

0 references

publication date

6 September 2010

1 reference

23 August 2017

1 reference

23 August 2017

volume

29

1 reference

23 August 2017

issue

46

1 reference

23 August 2017

page(s)

6085-6098

1 reference

https://scigraph.springernature.com/pub.10.1038/onc.2010.407

23 August 2017

exact match

0 references

cites work

Cell cycle checkpoint signaling through the ATM and ATR kinases

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.407

Preventing nonhomologous end joining suppresses DNA repair defects of Fanconi anemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.407

The Bcl-2 apoptotic switch in cancer development and therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.407

Distinct Initiation and Maintenance Mechanisms Cooperate to Induce G1 Cell Cycle Arrest in Response to DNA Damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.407

APOMAB, a La-specific monoclonal antibody, detects the apoptotic tumor response to life-prolonging and DNA-damaging chemotherapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.407

p53-independent regulation of p21Waf1/Cip1 expression and senescence by Chk2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.407

Validating survivin as a cancer therapeutic target

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.407

DNA damage detection and repair pathways--recent advances with inhibitors of checkpoint kinases in cancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.407

Involvement of poly(ADP-ribose) polymerase-1 and XRCC1/DNA ligase III in an alternative route for DNA double-strand breaks rejoining.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.407

Priming phosphorylation of Chk2 by polo-like kinase 3 (Plk3) mediates its full activation by ATM and a downstream checkpoint in response to DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.407

New tricks for old drugs: the anticarcinogenic potential of DNA repair inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.407

Breaching the DNA damage checkpoint via PF-00477736, a novel small-molecule inhibitor of checkpoint kinase 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.407

DNA repair: Decision at the break point.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.407

53BP1 loss rescues BRCA1 deficiency and is associated with triple-negative and BRCA-mutated breast cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.407

Oncogene-induced senescence as an initial barrier in lymphoma development

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.407

Regulation of DNA repair throughout the cell cycle

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.407

Apoptosis genes and resistance to cancer therapy: what does the experimental and clinical data tell us?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.407

Apoptosis: mediator or mode of cell killing by anticancer agents?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.407

Inhibition of poly (ADP-ribose) polymerase activates ATM which is required for subsequent homologous recombination repair

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.407

Specific killing of BRCA2-deficient tumours with inhibitors of poly(ADP-ribose) polymerase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.407

G2 checkpoint abrogation and checkpoint kinase-1 targeting in the treatment of cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.407

53BP1 inhibits homologous recombination in Brca1-deficient cells by blocking resection of DNA breaks

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.407

Anticancer chemosensitization and radiosensitization by the novel poly(ADP-ribose) polymerase-1 inhibitor AG14361.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.407

Crucial role of p53-dependent cellular senescence in suppression of Pten-deficient tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.407

Selective Chk1 inhibitors differentially sensitize p53-deficient cancer cells to cancer therapeutics

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.407

Chk1 is essential for tumor cell viability following activation of the replication checkpoint

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.407

Tumour biology: senescence in premalignant tumours

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.407

Sensitization of breast carcinoma cells to ionizing radiation by small molecule inhibitors of DNA-dependent protein kinase and ataxia telangiectsia mutated

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.407

Unleashing the power of inhibitors of oncogenic kinases through BH3 mimetics

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.407

Novel poly(ADP-ribose) polymerase-1 inhibitor, AG14361, restores sensitivity to temozolomide in mismatch repair-deficient cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.407

Apoptosis and non-apoptotic deaths in cancer development and treatment response

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.407

Targeted disruption of the cell-cycle checkpoint gene ATR leads to early embryonic lethality in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.407

Survivin: a promising tumor biomarker

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.407

Life and death partners: apoptosis, autophagy and the cross-talk between them

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.407

Selective inhibition of BRCA2-deficient mammary tumor cell growth by AZD2281 and cisplatin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.407

H2AX phosphorylation marks gemcitabine-induced stalled replication forks and their collapse upon S-phase checkpoint abrogation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.407

Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.407

How nucleotide excision repair protects against cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.407

Absence of specific cell killing of the BRCA2-deficient human cancer cell line CAPAN1 by poly(ADP-ribose) polymerase inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.407

Cancer cells display profound intra- and interline variation following prolonged exposure to antimitotic drugs.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.407

Ataxia-telangiectasia-mutated (ATM) and NBS1-dependent phosphorylation of Chk1 on Ser-317 in response to ionizing radiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.407

BH3 peptidomimetics potently activate apoptosis and demonstrate single agent efficacy in neuroblastoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.407

Selective benzopyranone and pyrimido[2,1-a]isoquinolin-4-one inhibitors of DNA-dependent protein kinase: synthesis, structure-activity studies, and radiosensitization of a human tumor cell line in vitro.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.407

Targeting poly(ADP-ribosyl)ation: a promising approach in cancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.407

21 January 2018

The Hallmarks of Cancer

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.407

Discovery of potent chromen-4-one inhibitors of the DNA-dependent protein kinase (DNA-PK) using a small-molecule library approach

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.407

The DNA damage response: ten years after

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.407

Evidence that DNA damage detection machinery participates in DNA repair

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.407

Restoration of an absent G1 arrest and protection from apoptosis in embryonic stem cells after ionizing radiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.407

The inhibitors of apoptosis (IAPs) as cancer targets

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.407

DNA and its associated processes as targets for cancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.407

Backup pathways of NHEJ in cells of higher eukaryotes: cell cycle dependence

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.407

SU11752 inhibits the DNA-dependent protein kinase and DNA double-strand break repair resulting in ionizing radiation sensitization

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.407

ATM- and cell cycle-dependent regulation of ATR in response to DNA double-strand breaks

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.407

How does radiation kill cells?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.407

Prognostic significance of 99mTc Hynic-rh-annexin V scintigraphy during platinum-based chemotherapy in advanced lung cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.407

Loss of 53BP1 is a gain for BRCA1 mutant cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.407

DNA repair proteins as molecular targets for cancer therapeutics

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.407

DNA repair pathways in clinical practice: lessons from pediatric cancer susceptibility syndromes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.407

DNA double-strand breaks: signaling, repair and the cancer connection

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.407

Recent advances in understanding the cell death pathways activated by anticancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.407

Classification of cell death: recommendations of the Nomenclature Committee on Cell Death 2009

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.407

BH3-only proteins in cell death initiation, malignant disease and anticancer therapy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.407

IAP-targeted therapies for cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.407

p38 Mitogen-activated protein kinase- and HuR-dependent stabilization of p21(Cip1) mRNA mediates the G(1)/S checkpoint

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.407

Deregulated E2F activity induces hyperplasia and senescence-like features in the mouse pituitary gland

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.407

Identification of a highly potent and selective DNA-dependent protein kinase (DNA-PK) inhibitor (NU7441) by screening of chromenone libraries

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.407

DNA damage repair and response proteins as targets for cancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.407

19F-NMR detection of lacZ gene expression via the enzymic hydrolysis of 2-fluoro-4-nitrophenyl beta-D-galactopyranoside in vivo in PC3 prostate tumor xenografts in the mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.407

Dial 9-1-1 for p53: mechanisms of p53 activation by cellular stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.407

Targeted therapy for cancer using PARP inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.407

Targeting the double-strand DNA break repair pathway as a therapeutic strategy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.407

Cell survival, cell death and cell cycle pathways are interconnected: implications for cancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.407

p21 Waf1/Cip1 can protect human colon carcinoma cells against p53-dependent and p53-independent apoptosis induced by natural chemopreventive and therapeutic agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.407

Targeting phosphoinositide 3-kinase: moving towards therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.407

RAD51 up-regulation bypasses BRCA1 function and is a common feature of BRCA1-deficient breast tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.407

Cleavage-mediated activation of Chk1 during apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.407

Pharmacological abrogation of S-phase checkpoint enhances the anti-tumor activity of gemcitabine in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.407

BRCA2-deficient CAPAN-1 cells are extremely sensitive to the inhibition of Poly (ADP-Ribose) polymerase: an issue of potency

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.407

p53: a guide to apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.407

BRAFE600-associated senescence-like cell cycle arrest of human naevi

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.407

Role of checkpoint kinase 1 in preventing premature mitosis in response to gemcitabine

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.407

21 January 2018

The Plk3-Cdc25 circuit

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.407

ATR and Chk1 suppress a caspase-3-dependent apoptotic response following DNA replication stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.407

Radiosensitization by the poly(ADP-ribose) polymerase inhibitor 4-amino-1,8-naphthalimide is specific of the S phase of the cell cycle and involves arrest of DNA synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.407

Targeted cancer therapies based on the inhibition of DNA strand break repair

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.407

Validation of the Royal Marsden hospital prognostic index in advanced esophagogastric cancer using individual patient data from the REAL 2 study

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.407

Checkpoint kinase 1 is cleaved in a caspase-dependent pathway during genotoxic stress-induced apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.407

Ku70 corrupts DNA repair in the absence of the Fanconi anemia pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.407

Gemcitabine sensitization by checkpoint kinase 1 inhibition correlates with inhibition of a Rad51 DNA damage response in pancreatic cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.407

Inhibition of poly(ADP-ribose) polymerase in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.407

Targeting poly(ADP-ribose) polymerase: a two-armed strategy for cancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.407

Mechanisms of drug-induced mitotic catastrophe in cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.407

Targeting the DNA damage response for cancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.407

Stem cells, senescence, neosis and self-renewal in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.407

Current development of clinical inhibitors of poly(ADP-ribose) polymerase in oncology

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.407

Drug insight: cancer therapy strategies based on restoration of endogenous cell death mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.407

Proapoptotic multidomain Bcl-2/Bax-family proteins: mechanisms, physiological roles, and therapeutic opportunities

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.407

p53-deficient cells rely on ATM- and ATR-mediated checkpoint signaling through the p38MAPK/MK2 pathway for survival after DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.407

Kinases that control the cell cycle in response to DNA damage: Chk1, Chk2, and MK2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.407

Escape from therapy-induced accelerated cellular senescence in p53-null lung cancer cells and in human lung cancers.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.407

Parp1 facilitates alternative NHEJ, whereas Parp2 suppresses IgH/c-myc translocations during immunoglobulin class switch recombination

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.407

Apoptosis induced by replication inhibitors in Chk1-depleted cells is dependent upon the helicase cofactor Cdc45.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.407

Chk1 and p21 cooperate to prevent apoptosis during DNA replication fork stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.407

Tumor senescence as a determinant of drug response in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.407

If not apoptosis, then what? Treatment-induced senescence and mitotic catastrophe in tumor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.407

Molecular mechanisms of mammalian DNA repair and the DNA damage checkpoints

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.407

Inactivation of DNA-dependent protein kinase leads to spindle disruption and mitotic catastrophe with attenuated checkpoint protein 2 Phosphorylation in response to DNA damage.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.407

DNA-dependent protein kinase is a molecular target for the development of noncytotoxic radiation-sensitizing drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.407

Regulation of DNA double-strand break repair pathway choice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.407

Chk1 suppresses a caspase-2 apoptotic response to DNA damage that bypasses p53, Bcl-2, and caspase-3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.407

Role of senescence and mitotic catastrophe in cancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.407

ATR-dependent phosphorylation and activation of ATM in response to UV treatment or replication fork stalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.407

Effect of combined DNA repair inhibition and G2 checkpoint inhibition on cell cycle progression after DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.407

Chk1 inhibitors for novel cancer treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.407

p53 suppression of arsenite-induced mitotic catastrophe is mediated by p21CIP1/WAF1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.407

Non-classical p38 map kinase functions: cell cycle checkpoints and survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.407

CHIR-124, a novel potent inhibitor of Chk1, potentiates the cytotoxicity of topoisomerase I poisons in vitro and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.407

In vivo imaging of beta-galactosidase activity using far red fluorescent switch

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.407

p73 induction after DNA damage is regulated by checkpoint kinases Chk1 and Chk2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.407

DNA damage induces two distinct modes of cell death in ovarian carcinomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.407

Death through a tragedy: mitotic catastrophe

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.407

Effects of novel inhibitors of poly(ADP-ribose) polymerase-1 and the DNA-dependent protein kinase on enzyme activities and DNA repair.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.407

BCL-2 in the crosshairs: tipping the balance of life and death

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.407

DNA ligase III as a candidate component of backup pathways of nonhomologous end joining

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.407

PARP-1 and Ku compete for repair of DNA double strand breaks by distinct NHEJ pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.407

Centrosome-associated regulators of the G(2)/M checkpoint as targets for cancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.407

The increment of micronucleus frequency in cervical carcinoma during irradiation in vivo and its prognostic value for tumour radiocurability.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.407

A novel DNA-dependent protein kinase inhibitor, NU7026, potentiates the cytotoxicity of topoisomerase II poisons used in the treatment of leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.407

DNA-dependent protein kinase is a therapeutic target and an indicator of poor prognosis in B-cell chronic lymphocytic leukemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.407

Repair of radiation induced DNA double strand breaks by backup NHEJ is enhanced in G2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.407

PF-00477736 mediates checkpoint kinase 1 signaling pathway and potentiates docetaxel-induced efficacy in xenografts

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.407

BH3 mimetics to improve cancer therapy; mechanisms and examples

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.407

Preclinical evaluation of a potent novel DNA-dependent protein kinase inhibitor NU7441.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.407

Targeting the checkpoint kinases: chemosensitization versus chemoprotection

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.407

The DNA damage response: putting checkpoints in perspective

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.407

BCL2 family in DNA damage and cell cycle control

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.407

Immunotargeting of Functional Nanoparticles for MRI detection of Apoptotic Tumor Cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.407

Effect of double-strand break DNA sequence on the PARP-1 NHEJ pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.407

Prediction of radiosensitivity of oral cancers by serial cytological assay of nuclear changes

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.407

Role of p53 and p21waf1/cip1 in senescence-like terminal proliferation arrest induced in human tumor cells by chemotherapeutic drugs

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.407

Monitoring of chemotherapy-induced cell death in melanoma tumors by N,N'-Didansyl-L-cystine

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.407

What drives success for specialty pharmaceuticals?

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.407

Deficiency in the Repair of DNA Damage by Homologous Recombination and Sensitivity to Poly(ADP-Ribose) Polymerase Inhibition

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.407

Radiation-induced centrosome overduplication and multiple mitotic spindles in human tumor cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.407

A senescence program controlled by p53 and p16INK4a contributes to the outcome of cancer therapy

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.407

Predictive assays for the therapy of rectum carcinoma

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.407

Micronuclei and nuclear abnormalities observed in erythroblasts in myelodysplastic syndromes and in de novo acute leukemia after treatment

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.407

Changes in S-phase fraction and micronucleus frequency as prognostic factors in radiotherapy of cervical carcinoma

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2010.407

31 March 2020

Identifiers

DOI

10.1038/ONC.2010.407

1 reference

23 August 2017

1 reference