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Mouse models of Alzheimer's disease
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scholarly article
1 reference
stated in
Europe PubMed Central
PMCID
3546481
retrieved
26 August 2017
title
Mouse models of Alzheimer's disease
(English)
1 reference
stated in
Europe PubMed Central
PMCID
3546481
retrieved
26 August 2017
main subject
Alzheimer's disease
0 references
author
Erik D. Roberson
object named as
Erik D Roberson
series ordinal
2
0 references
author name string
Alicia M Hall
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMCID
3546481
retrieved
26 August 2017
publication date
28 November 2011
1 reference
stated in
Europe PubMed Central
PMCID
3546481
retrieved
26 August 2017
published in
Brain Research Bulletin
1 reference
stated in
Europe PubMed Central
PMCID
3546481
retrieved
26 August 2017
volume
88
1 reference
stated in
Europe PubMed Central
PMCID
3546481
retrieved
26 August 2017
page(s)
3-12
1 reference
stated in
Europe PubMed Central
PMCID
3546481
retrieved
26 August 2017
issue
1
1 reference
stated in
Europe PubMed Central
PMCID
3546481
retrieved
26 August 2017
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Amyloid-β/Fyn-induced synaptic, network, and cognitive impairments depend on tau levels in multiple mouse models of Alzheimer's disease.
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6 September 2017
'Too much good news' - are Alzheimer mouse models trying to tell us how to prevent, not cure, Alzheimer's disease?
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Age-dependent impairment of cognitive and synaptic function in the htau mouse model of tau pathology
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6 September 2017
Failures to reconsolidate memory in a mouse model of Alzheimer's disease
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6 September 2017
Impairments in remote memory stabilization precede hippocampal synaptic and cognitive failures in 5XFAD Alzheimer mouse model
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Induction of tau pathology by intracerebral infusion of amyloid-beta -containing brain extract and by amyloid-beta deposition in APP x Tau transgenic mice
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6 September 2017
BACE1 gene deletion prevents neuron loss and memory deficits in 5XFAD APP/PS1 transgenic mice
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6 September 2017
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6 September 2017
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6 September 2017
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6 September 2017
Long-lasting impairment in hippocampal neurogenesis associated with amyloid deposition in a knock-in mouse model of familial Alzheimer's disease
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6 September 2017
Pathological and physiological functions of presenilins
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6 September 2017
APP processing and the APP-KPI domain involvement in the amyloid cascade.
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6 September 2017
A specific amyloid-beta protein assembly in the brain impairs memory
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6 September 2017
AMPA receptor downscaling at the onset of Alzheimer's disease pathology in double knockin mice.
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6 September 2017
Abeta42 is essential for parenchymal and vascular amyloid deposition in mice
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6 September 2017
Massive CA1/2 neuronal loss with intraneuronal and N-terminal truncated Abeta42 accumulation in a novel Alzheimer transgenic model
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6 September 2017
Identification of the role of presenilins beyond Alzheimer's disease
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6 September 2017
The current status of Alzheimer's disease genetics: what do we tell the patients?
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6 September 2017
Mutant presenilins specifically elevate the levels of the 42 residue beta-amyloid peptide in vivo: evidence for augmentation of a 42-specific gamma secretase
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6 September 2017
Carboxyl-terminal-truncated apolipoprotein E4 causes Alzheimer's disease-like neurodegeneration and behavioral deficits in transgenic mice
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6 September 2017
The prevalence and causes of dementia in people under the age of 65 years
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6 September 2017
Triple-transgenic model of Alzheimer's disease with plaques and tangles: intracellular Abeta and synaptic dysfunction
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6 September 2017
Neuronal depletion of calcium-dependent proteins in the dentate gyrus is tightly linked to Alzheimer's disease-related cognitive deficits
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6 September 2017
Learning and memory deficits in APP transgenic mouse models of amyloid deposition
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6 September 2017
Initial sequencing and comparative analysis of the mouse genome
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6 September 2017
Spatial learning, exploration, anxiety, and motor coordination in female APP23 transgenic mice with the Swedish mutation
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6 September 2017
Impaired cell cycle control of neuronal precursor cells in the neocortical primordium of presenilin-1-deficient mice
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PubMed Central
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6 September 2017
The aspartate-257 of presenilin 1 is indispensable for mouse development and production of beta-amyloid peptides through beta-catenin-independent mechanisms
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6 September 2017
Charge states rather than propensity for beta-structure determine enhanced fibrillogenesis in wild-type Alzheimer's beta-amyloid peptide compared to E22Q Dutch mutant
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6 September 2017
Tau is essential to beta -amyloid-induced neurotoxicity
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6 September 2017
The relationship between Abeta and memory in the Tg2576 mouse model of Alzheimer's disease.
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6 September 2017
Introduction of human apolipoprotein E4 "domain interaction" into mouse apolipoprotein E
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6 September 2017
The 'Arctic' APP mutation (E693G) causes Alzheimer's disease by enhanced Abeta protofibril formation
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6 September 2017
Enhanced neurofibrillary degeneration in transgenic mice expressing mutant tau and APP.
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6 September 2017
BACE1 is the major beta-secretase for generation of Abeta peptides by neurons
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6 September 2017
A learning deficit related to age and beta-amyloid plaques in a mouse model of Alzheimer's disease
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6 September 2017
Age-related amyloid beta deposition in transgenic mice overexpressing both Alzheimer mutant presenilin 1 and amyloid beta precursor protein Swedish mutant is not associated with global neuronal loss
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6 September 2017
High-level neuronal expression of abeta 1-42 in wild-type human amyloid protein precursor transgenic mice: synaptotoxicity without plaque formation
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6 September 2017
Immunization with amyloid-beta attenuates Alzheimer-disease-like pathology in the PDAPP mouse
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6 September 2017
Plaque-independent disruption of neural circuits in Alzheimer's disease mouse models
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6 September 2017
Doxycycline control of prion protein transgene expression modulates prion disease in mice
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6 September 2017
Isoform-specific effects of human apolipoprotein E on brain function revealed in ApoE knockout mice: increased susceptibility of females
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6 September 2017
Association of missense and 5'-splice-site mutations in tau with the inherited dementia FTDP-17
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6 September 2017
Mutation in the tau gene in familial multiple system tauopathy with presenile dementia
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PubMed Central
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6 September 2017
Deficiency of presenilin-1 inhibits the normal cleavage of amyloid precursor protein
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PubMed Central
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6 September 2017
Accelerated Alzheimer-type phenotype in transgenic mice carrying both mutant amyloid precursor protein and presenilin 1 transgenes
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PubMed Central
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6 September 2017
Effects of age, sex, and ethnicity on the association between apolipoprotein E genotype and Alzheimer disease. A meta-analysis. APOE and Alzheimer Disease Meta Analysis Consortium
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PubMed Central
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6 September 2017
Mutant presenilins of Alzheimer's disease increase production of 42-residue amyloid beta-protein in both transfected cells and transgenic mice
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3546481
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6 September 2017
Familial Alzheimer's disease-linked presenilin 1 variants elevate Abeta1-42/1-40 ratio in vitro and in vivo
1 reference
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PubMed Central
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6 September 2017
Developmental abnormalities and age-related neurodegeneration in a mouse model of Down syndrome
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PubMed Central
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6 September 2017
Increased amyloid-beta42(43) in brains of mice expressing mutant presenilin 1
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PubMed Central
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6 September 2017
Correlative Memory Deficits, Abeta Elevation, and Amyloid Plaques in Transgenic Mice
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6 September 2017
Gene-targeting studies of mammalian behavior: is it the mutation or the background genotype?
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6 September 2017
Apolipoprotein E: high-avidity binding to beta-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease
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6 September 2017
Increased amyloid beta-peptide deposition in cerebral cortex as a consequence of apolipoprotein E genotype in late-onset Alzheimer disease
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6 September 2017
Association of apolipoprotein E allele epsilon 4 with late-onset familial and sporadic Alzheimer's disease
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6 September 2017
Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families
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6 September 2017
Candidate gene for the chromosome 1 familial Alzheimer's disease locus
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6 September 2017
Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease
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6 September 2017
Biochemistry of altered brain proteins in Alzheimer's disease
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6 September 2017
Segmental trisomy of murine chromosome 16: a new model system for studying Down syndrome
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6 September 2017
Tissue-specific control elements of the Thy-1 gene
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6 September 2017
Early-onset Alzheimer's disease caused by mutations at codon 717 of the beta-amyloid precursor protein gene
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6 September 2017
Physical basis of cognitive alterations in alzheimer's disease: Synapse loss is the major correlate of cognitive impairment
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6 September 2017
Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease
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6 September 2017
Neurofibrillary tangles but not senile plaques parallel duration and severity of Alzheimer's disease
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6 September 2017
Mutation of the beta-amyloid precursor protein in familial Alzheimer's disease increases beta-protein production
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6 September 2017
Distinct genetic forms of frontotemporal dementia.
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14 September 2017
Expression mapping of tetracycline-responsive prion protein promoter: digital atlasing for generating cell-specific disease models.
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14 September 2017
Down's syndrome and Alzheimer's dementia: defining an association
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14 September 2017
FAD mutant PS-1 gene-targeted mice: increased A beta 42 and A beta deposition without APP overproduction
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28 September 2017
Glu11 site cleavage and N-terminally truncated A beta production upon BACE overexpression
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28 September 2017
Expression of BRI-amyloid beta peptide fusion proteins: a novel method for specific high-level expression of amyloid beta peptides
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PubMed Central
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28 September 2017
Overexpression of growth-associated proteins in the neurons of adult transgenic mice
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28 September 2017
Cellular source of apolipoprotein E4 determines neuronal susceptibility to excitotoxic injury in transgenic mice
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23 June 2018
Pathology associated memory deficits in Swedish mutant genome-based amyloid precursor protein transgenic mice.
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23 June 2018
Of mice and men: bridging the translational disconnect in CNS drug discovery
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23 June 2018
Intraneuronal beta-amyloid aggregates, neurodegeneration, and neuron loss in transgenic mice with five familial Alzheimer's disease mutations: potential factors in amyloid plaque formation.
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23 June 2018
Beta-secretase processing in the trans-Golgi network preferentially generates truncated amyloid species that accumulate in Alzheimer's disease brain
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PubMed Central
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23 June 2018
Behavioral phenotyping of GFAP-apoE3 and -apoE4 transgenic mice: apoE4 mice show profound working memory impairments in the absence of Alzheimer's-like neuropathology
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PubMed Central
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23 June 2018
Presenilin-1 P264L knock-in mutation: differential effects on abeta production, amyloid deposition, and neuronal vulnerability.
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23 June 2018
Neurofibrillary tangles, amyotrophy and progressive motor disturbance in mice expressing mutant (P301L) tau protein
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23 June 2018
Spatial learning in transgenic mice expressing human presenilin 1 (PS1) transgenes.
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23 June 2018
Aspartate mutations in presenilin and gamma-secretase inhibitors both impair notch1 proteolysis and nuclear translocation with relative preservation of notch1 signaling
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PubMed Central
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23 June 2018
Mutant presenilin 2 transgenic mouse: effect on an age-dependent increase of amyloid beta-protein 42 in the brain.
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23 June 2018
Mutant genes in familial Alzheimer's disease and transgenic models
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23 June 2018
Assessing the effects of the 129/Sv genetic background on swimming navigation learning in transgenic mutants: a study using mice with a modified beta-amyloid precursor protein gene.
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23 June 2018
Alzheimer transgenic mouse models come of age.
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23 June 2018
The alternatively spliced Kunitz protease inhibitor domain alters amyloid beta protein precursor processing and amyloid beta protein production in cultured cells.
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PubMed Central
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23 June 2018
Alzheimer's disease associated with mutations in presenilin 2 is rare and variably penetrant.
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23 June 2018
Enhanced amyloidogenic processing of the beta-amyloid precursor protein in gene-targeted mice bearing the Swedish familial Alzheimer's disease mutations and a "humanized" Abeta sequence.
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PubMed Central
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23 June 2018
Transgenic mice expressing human beta-APP751, but not mice expressing beta-APP695, display early Alzheimer's disease-like histopathology
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PubMed Central
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23 June 2018
An increased percentage of long amyloid beta protein secreted by familial amyloid beta protein precursor (beta APP717) mutants.
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23 June 2018
Rapid induction of Alzheimer A beta amyloid formation by zinc.
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23 June 2018
In vivo neuronal synthesis and axonal transport of Kunitz protease inhibitor (KPI)-containing forms of the amyloid precursor protein.
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23 June 2018
A mouse model for Down syndrome exhibits learning and behaviour deficits.
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23 June 2018
Differences between inbred strains of mice in Morris water maze performance.
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23 June 2018
Tissue-specific expression of three types of beta-protein precursor mRNA: enhancement of protease inhibitor-harboring types in Alzheimer's disease brain.
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23 June 2018
Mutation of the Alzheimer's disease amyloid gene in hereditary cerebral hemorrhage, Dutch type.
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23 June 2018
PDGF B-chain in neurons of the central nervous system, posterior pituitary, and in a transgenic model
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23 June 2018
Protease-specificity of Kunitz inhibitor domain of Alzheimer's disease amyloid protein precursor.
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23 June 2018
Age-related changes in the proportion of amyloid precursor protein mRNAs in Alzheimer's disease and other neurological disorders
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23 June 2018
Strain specific differences in memory and neuropathology in a mouse model of Alzheimer's disease.
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1 September 2018
Human APOE isoform-dependent effects on brain beta-amyloid levels in PDAPP transgenic mice.
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1 September 2018
Middle-aged human apoE4 targeted-replacement mice show retention deficits on a wide range of spatial memory tasks.
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3546481
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1 September 2018
Modulation of synaptic plasticity and Tau phosphorylation by wild-type and mutant presenilin1.
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1 September 2018
Phenotype associated with APP duplication in five families.
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1 September 2018
Profile and regulation of apolipoprotein E (ApoE) expression in the CNS in mice with targeting of green fluorescent protein gene to the ApoE locus.
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3546481
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1 September 2018
Targeting soluble Abeta peptide with Tramiprosate for the treatment of brain amyloidosis.
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3546481
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1 September 2018
Cell-cycle reentry and cell death in transgenic mice expressing nonmutant human tau isoforms.
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3546481
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1 September 2018
Age-progressing cognitive impairments and neuropathology in transgenic CRND8 mice.
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3546481
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1 September 2018
Human apoE targeted replacement mouse lines: h-apoE4 and h-apoE3 mice differ on spatial memory performance and avoidance behavior.
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3546481
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1 September 2018
Human apolipoprotein E4 alters the amyloid-beta 40:42 ratio and promotes the formation of cerebral amyloid angiopathy in an amyloid precursor protein transgenic model.
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3546481
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1 September 2018
Episodic-like memory deficits in the APPswe/PS1dE9 mouse model of Alzheimer's disease: relationships to beta-amyloid deposition and neurotransmitter abnormalities
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3546481
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1 September 2018
Intraneuronal Abeta causes the onset of early Alzheimer's disease-related cognitive deficits in transgenic mice
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3546481
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1 September 2018
ApoE isoform affects LTP in human targeted replacement mice.
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3546481
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1 September 2018
Cerebrospinal fluid beta-amyloid1-42 and tau in control subjects at risk for Alzheimer's disease: the effect of APOE epsilon4 allele
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3546481
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1 September 2018
Aggressive amyloidosis in mice expressing human amyloid peptides with the Arctic mutation
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3546481
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1 September 2018
A behavioural characterisation of the FVB/N mouse strain.
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3546481
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1 September 2018
Abeta immunotherapy leads to clearance of early, but not late, hyperphosphorylated tau aggregates via the proteasome
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3546481
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1 September 2018
The presenilin-1 familial Alzheimer disease mutant P117L impairs neurogenesis in the hippocampus of adult mice
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3546481
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1 September 2018
APP processing and amyloid deposition in mice haplo-insufficient for presenilin 1.
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1 September 2018
Impact of APOE genotype on neuropathologic and neurochemical markers of Alzheimer disease
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3546481
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1 September 2018
Targeted introduction of V642I mutation in amyloid precursor protein gene causes functional abnormality resembling early stage of Alzheimer's disease in aged mice.
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3546481
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1 September 2018
Amyloid deposition precedes tangle formation in a triple transgenic model of Alzheimer's disease.
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3546481
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1 September 2018
Behavioral and neurochemical characterization of transgenic mice carrying the human presenilin-1 gene with or without the leucine-to-proline mutation at codon 235.
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1 September 2018
Hyperphosphorylation and aggregation of tau in mice expressing normal human tau isoforms.
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1 September 2018
Reconstitution of gamma-secretase activity
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1 September 2018
Transgenic mice expressing the PS1-A246E mutation: effects on spatial learning, exploration, anxiety, and motor coordination.
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3546481
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1 September 2018
Expression pattern of a mini human PrP gene promoter in transgenic mice.
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1 September 2018
Alterations in behavior, amyloid beta-42, caspase-3, and Cox-2 in mutant PS2 transgenic mouse model of Alzheimer's disease.
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1 September 2018
Intra- and intertask relationships in a behavioral test battery given to Tg2576 transgenic mice and controls.
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3546481
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1 September 2018
Accelerated plaque accumulation, associative learning deficits, and up-regulation of alpha 7 nicotinic receptor protein in transgenic mice co-expressing mutant human presenilin 1 and amyloid precursor proteins
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3546481
retrieved
1 September 2018
Behavioral assessment of Alzheimer's transgenic mice following long-term Abeta vaccination: task specificity and correlations between Abeta deposition and spatial memory.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3546481
retrieved
1 September 2018
Early formation of mature amyloid-beta protein deposits in a mutant APP transgenic model depends on levels of Abeta(1-42).
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3546481
retrieved
1 September 2018
Formation of neurofibrillary tangles in P301l tau transgenic mice induced by Abeta 42 fibrils
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3546481
retrieved
1 September 2018
Early-onset amyloid deposition and cognitive deficits in transgenic mice expressing a double mutant form of amyloid precursor protein 695.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3546481
retrieved
1 September 2018
Reduced antioxidant enzyme activity in brains of mice transgenic for human presenilin-1 with single or multiple mutations.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3546481
retrieved
1 September 2018
Mitochondrial damage in Alzheimer's disease varies with apolipoprotein E genotype.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3546481
retrieved
1 September 2018
Behavioral disturbances in transgenic mice overexpressing the V717F beta-amyloid precursor protein.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3546481
retrieved
1 September 2018
Behavioral changes in transgenic mice expressing both amyloid precursor protein and presenilin-1 mutations: lack of association with amyloid deposits.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3546481
retrieved
1 September 2018
Amyloid production and deposition in mutant amyloid precursor protein and presenilin-1 yeast artificial chromosome transgenic mice.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3546481
retrieved
1 September 2018
Accumulation of murine amyloidbeta42 in a gene-dosage-dependent manner in PS1 'knock-in' mice.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3546481
retrieved
1 September 2018
Transgenic mice with Alzheimer presenilin 1 mutations show accelerated neurodegeneration without amyloid plaque formation.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3546481
retrieved
1 September 2018
The kunitz protease inhibitor form of the amyloid precursor protein (KPI/APP) inhibits the proneuropeptide processing enzyme prohormone thiol protease (PTP). Colocalization of KPI/APP and PTP in secretory vesicles
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3546481
retrieved
1 September 2018
Increased vulnerability of hippocampal neurons to excitotoxic necrosis in presenilin-1 mutant knock-in mice.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3546481
retrieved
1 September 2018
Relative increase in Alzheimer's disease of soluble forms of cerebral Abeta amyloid protein precursor containing the Kunitz protease inhibitory domain.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3546481
retrieved
1 September 2018
Genetic modification of the phenotypes produced by amyloid precursor protein overexpression in transgenic mice.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3546481
retrieved
1 September 2018
Altered metabolism of familial Alzheimer's disease-linked amyloid precursor protein variants in yeast artificial chromosome transgenic mice.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3546481
retrieved
1 September 2018
Assessment of learning by the Morris water task and fear conditioning in inbred mouse strains and F1 hybrids: implications of genetic background for single gene mutations and quantitative trait loci analyses.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3546481
retrieved
1 September 2018
Age-related CNS disorder and early death in transgenic FVB/N mice overexpressing Alzheimer amyloid precursor proteins.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3546481
retrieved
1 September 2018
Levels and alternative splicing of amyloid beta protein precursor (APP) transcripts in brains of APP transgenic mice and humans with Alzheimer's disease.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3546481
retrieved
1 September 2018
Characterization of pathology in transgenic mice over-expressing human genomic and cDNA tau transgenes
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/22142973
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Aging increased amyloid peptide and caused amyloid plaques in brain of old APP/V717I transgenic mice by a different mechanism than mutant presenilin1
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/22142973
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Changed conformation of mutant Tau-P301L underlies the moribund tauopathy, absent in progressive, nonlethal axonopathy of Tau-4R/2N transgenic mice
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/22142973
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Amyloid beta protein precursor gene and hereditary cerebral hemorrhage with amyloidosis (Dutch)
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/22142973
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Regulation of Thy-1 gene expression in transgenic mice
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/22142973
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Neuron loss in APP transgenic mice
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/22142973
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1016/J.BRAINRESBULL.2011.11.017
1 reference
stated in
Europe PubMed Central
PMCID
3546481
retrieved
26 August 2017
PMCID
3546481
1 reference
stated in
Europe PubMed Central
PMCID
3546481
retrieved
26 August 2017
PubMed ID
22142973
1 reference
stated in
Europe PubMed Central
PMCID
3546481
retrieved
26 August 2017
ResearchGate publication ID
51854096
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