(Q38107993)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23688078%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

title

ABC transporters in multidrug resistance and pharmacokinetics, and strategies for drug development (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23688078%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

main subject

multiple drug resistance

1 reference

1 reference

Young Hee Choi

1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23688078%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

Ai-Ming Yu

series ordinal

2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23688078%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

publication date

1 January 2014

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23688078%20AND%20SRC:MED&resulttype=core&format=json

Current Pharmaceutical Design

1 March 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23688078%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

volume

20

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23688078%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

issue

5

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23688078%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

page(s)

793-807

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23688078%20AND%20SRC:MED&resulttype=core&format=json

Stimulation of P-glycoprotein-mediated drug transport by prazosin and progesterone. Evidence for a third drug-binding site.

1 March 2020

cites work

1 reference

12 December 2020

Biochemical, cellular, and pharmacological aspects of the multidrug transporter

1 reference

12 December 2020

The role of intestinal P-glycoprotein in the interaction of digoxin and rifampin

1 reference

12 December 2020

Frequency and clinical significance of the expression of the multidrug resistance proteins MDR1/P-glycoprotein, MRP1, and LRP in acute myeloid leukemia: a Southwest Oncology Group Study

1 reference

12 December 2020

Species differences in the transport activity for organic anions across the bile canalicular membrane.

1 reference

12 December 2020

Longitudinal assessment of a P-glycoprotein-mediated drug interaction of valspodar on digoxin

1 reference

12 December 2020

ATPase activity of purified and reconstituted multidrug resistance protein MRP1 from drug-selected H69AR cells

1 reference

12 December 2020

Rapid activation of MDR1 gene expression in human metastatic sarcoma after in vivo exposure to doxorubicin

1 reference

12 December 2020

Altered expression of hepatic cytochromes P-450 in mice deficient in one or more mdr1 genes.

1 reference

12 December 2020

Multidrug resistance protein 1 protects the choroid plexus epithelium and contributes to the blood-cerebrospinal fluid barrier

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12 December 2020

The packing of the transmembrane segments of human multidrug resistance P-glycoprotein is revealed by disulfide cross-linking analysis.

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12 December 2020

Acute heart transplant rejection due to Saint John's wort

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12 December 2020

Development of an in situ mouse brain perfusion model and its application to mdr1a P-glycoprotein-deficient mice

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12 December 2020

In vitro flow cytometry method to quantitatively assess inhibitors of P-glycoprotein

1 reference

12 December 2020

Multidrug resistance (MDR) in cancer. Mechanisms, reversal using modulators of MDR and the role of MDR modulators in influencing the pharmacokinetics of anticancer drugs

1 reference

12 December 2020

Induction of P-glycoprotein by rifampin increases intestinal secretion of talinolol in human beings: a new type of drug/drug interaction

1 reference

12 December 2020

5-Fluorouracil: forty-plus and still ticking. A review of its preclinical and clinical development

1 reference

12 December 2020

Modulation of oral bioavailability of anticancer drugs: from mouse to man.

1 reference

12 December 2020

Phase I trial of XR9576 in healthy volunteers demonstrates modulation of P-glycoprotein in CD56+ lymphocytes after oral and intravenous administration.

1 reference

12 December 2020

Astrocytes increase the functional expression of P-glycoprotein in an in vitro model of the blood-brain barrier.

1 reference

12 December 2020

The Sequence of the Human Genome

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12 December 2020

Inactivation of the apoptosis effector Apaf-1 in malignant melanoma

1 reference

12 December 2020

Transport of opioids from the brain to the periphery by P-glycoprotein: peripheral actions of central drugs

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12 December 2020

Initial sequencing and analysis of the human genome

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12 December 2020

Activity of a specific inhibitor of the BCR-ABL tyrosine kinase in the blast crisis of chronic myeloid leukemia and acute lymphoblastic leukemia with the Philadelphia chromosome

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12 December 2020

Screening of multidrug-resistance sensitive drugs by in situ brain perfusion in P-glycoprotein-deficient mice

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12 December 2020

Clinical resistance to STI-571 cancer therapy caused by BCR-ABL gene mutation or amplification

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12 December 2020

The human ATP-binding cassette (ABC) transporter superfamily

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12 December 2020

Functional characterization of the human multidrug transporter, ABCG2, expressed in insect cells

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12 December 2020

Correlation of gene expression of ten drug efflux proteins of the ATP-binding cassette transporter family in normal human jejunum and in human intestinal epithelial Caco-2 cell monolayers.

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12 December 2020

Repacking of the transmembrane domains of P-glycoprotein during the transport ATPase cycle

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12 December 2020

Benefit of cyclosporine modulation of drug resistance in patients with poor-risk acute myeloid leukemia: a Southwest Oncology Group study

1 reference

12 December 2020

Dominant-negative inhibition of breast cancer resistance protein as drug efflux pump through the inhibition of S-S dependent homodimerization

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12 December 2020

Safety and efficacy of the multidrug-resistance inhibitor biricodar (VX-710) with concurrent doxorubicin in patients with anthracycline-resistant advanced soft tissue sarcoma

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12 December 2020

Imatinib induces durable hematologic and cytogenetic responses in patients with accelerated phase chronic myeloid leukemia: results of a phase 2 study

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12 December 2020

Multidrug resistance in cancer: role of ATP-dependent transporters

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12 December 2020

DNA and its associated processes as targets for cancer therapy

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12 December 2020

Mammalian ABC transporters in health and disease

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12 December 2020

Putative identification of functional interactions between DNA intercalating agents and topoisomerase II using the V79 in vitro micronucleus assay

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12 December 2020

Drug interaction studies between paclitaxel (Taxol) and OC144-093--a new modulator of MDR in cancer chemotherapy

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12 December 2020

Increased oral bioavailability of topotecan in combination with the breast cancer resistance protein and P-glycoprotein inhibitor GF120918.

1 reference

12 December 2020

Phase 3 study of the multidrug resistance modulator PSC-833 in previously untreated patients 60 years of age and older with acute myeloid leukemia: Cancer and Leukemia Group B Study 9720.

1 reference

12 December 2020

Bcrp1 gene expression is required for normal numbers of side population stem cells in mice, and confers relative protection to mitoxantrone in hematopoietic cells in vivo

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12 December 2020

Frequent expression of the multi-drug resistance-associated protein BCRP/MXR/ABCP/ABCG2 in human tumours detected by the BXP-21 monoclonal antibody in paraffin-embedded material

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12 December 2020

The breast cancer resistance protein protects against a major chlorophyll-derived dietary phototoxin and protoporphyria.

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12 December 2020

Three-dimensional structures of the mammalian multidrug resistance P-glycoprotein demonstrate major conformational changes in the transmembrane domains upon nucleotide binding

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12 December 2020

Mammalian drug efflux transporters of the ATP binding cassette (ABC) family: an overview.

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12 December 2020

Correlation of p53 status with outcome of neoadjuvant chemotherapy using paclitaxel and doxorubicin in stage IIIB breast cancer

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12 December 2020

Imatinib compared with interferon and low-dose cytarabine for newly diagnosed chronic-phase chronic myeloid leukemia

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12 December 2020

Issues and progress with protein kinase inhibitors for cancer treatment

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12 December 2020

Characterization of the transport of nucleoside analog drugs by the human multidrug resistance proteins MRP4 and MRP5

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12 December 2020

Safety and efficacy of the MDR inhibitor Incel (biricodar, VX-710) in combination with mitoxantrone and prednisone in hormone-refractory prostate cancer

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12 December 2020

Quantitative evaluation of the function of small intestinal P-glycoprotein: comparative studies between in situ and in vitro

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12 December 2020

The function of Gp170, the multidrug-resistance gene product, in the brush border of rat intestinal mucosa

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12 December 2020

Expression of the human multidrug resistance cDNA in insect cells generates a high activity drug-stimulated membrane ATPase

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12 December 2020

P-glycoprotein transports corticosterone and is photoaffinity-labeled by the steroid

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12 December 2020

Overexpression of a transporter gene in a multidrug-resistant human lung cancer cell line

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12 December 2020

Modulation of P-glycoprotein-mediated drug transport by alterations in lipid fluidity of rat liver canalicular membrane vesicles

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12 December 2020

Kinetic analysis of hepatobiliary transport of vincristine in perfused rat liver. Possible roles of P-glycoprotein in biliary excretion of vincristine

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12 December 2020

Wild-type breast cancer resistance protein (BCRP/ABCG2) is a methotrexate polyglutamate transporter

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12 December 2020

The breast cancer resistance protein (Bcrp1/Abcg2) restricts exposure to the dietary carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine.

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12 December 2020

Involvement of multidrug resistance associated protein 1 (Mrp1) in the efflux transport of 17beta estradiol-D-17beta-glucuronide (E217betaG) across the blood-brain barrier

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12 December 2020

Classification of anticancer drugs—a new system based on therapeutic targets

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12 December 2020

Breast cancer resistance protein impacts clinical outcome in platinum-based chemotherapy for advanced non-small cell lung cancer

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12 December 2020

VX-710 (biricodar) increases drug retention and enhances chemosensitivity in resistant cells overexpressing P-glycoprotein, multidrug resistance protein, and breast cancer resistance protein

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12 December 2020

Protein kinase inhibitors: insights into drug design from structure.

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12 December 2020

Microtubules as a target for anticancer drugs

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12 December 2020

Addition of cyclosporin A to the combination of mitoxantrone and etoposide to overcome resistance to chemotherapy in refractory or relapsing acute myeloid leukaemia: a randomised phase II trial from HOVON, the Dutch-Belgian Haemato-Oncology Working

1 reference

12 December 2020

The roles of transporters and enzymes in hepatic drug processing

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12 December 2020

Functional analysis of dog multidrug resistance-associated protein 2 (Mrp2) in comparison with rat Mrp2.

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12 December 2020

Dose escalation studies of cytarabine, daunorubicin, and etoposide with and without multidrug resistance modulation with PSC-833 in untreated adults with acute myeloid leukemia younger than 60 years: final induction results of Cancer and Leukemia Gr

1 reference

12 December 2020

Breast cancer resistance protein (BCRP/MXR/ABCG2) in adult acute lymphoblastic leukaemia: frequent expression and possible correlation with shorter disease-free survival

1 reference

12 December 2020

Role of breast cancer resistance protein (Bcrp1/Abcg2) in the extrusion of glucuronide and sulfate conjugates from enterocytes to intestinal lumen

1 reference

12 December 2020

The development of imatinib as a therapeutic agent for chronic myeloid leukemia

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12 December 2020

MDR1 and MRP1 gene expression are independent predictors for treatment outcome in adult acute myeloid leukaemia.

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12 December 2020

The breast cancer resistance protein BCRP (ABCG2) concentrates drugs and carcinogenic xenotoxins into milk.

1 reference

12 December 2020

Antimitotic activity and reversal of breast cancer resistance protein-mediated drug resistance by stilbenoids from Bletilla striata

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12 December 2020

Breast cancer resistance protein (BCRP/ABCG2).

1 reference

12 December 2020

Comparative analysis of two clinically active BCR-ABL kinase inhibitors reveals the role of conformation-specific binding in resistance

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12 December 2020

The breast cancer resistance protein (BCRP/ABCG2) affects pharmacokinetics, hepatobiliary excretion, and milk secretion of the antibiotic nitrofurantoin.

1 reference

12 December 2020

Expression, localization, and functional characteristics of breast cancer resistance protein in Caco-2 cells

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12 December 2020

EGFR mutation and resistance of non-small-cell lung cancer to gefitinib

1 reference

12 December 2020

Acquired resistance of lung adenocarcinomas to gefitinib or erlotinib is associated with a second mutation in the EGFR kinase domain

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12 December 2020

Role of the NH2-terminal membrane spanning domain of multidrug resistance protein 1/ABCC1 in protein processing and trafficking

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12 December 2020

cGMP (guanosine 3',5'-cyclic monophosphate) transport across human erythrocyte membranes

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12 December 2020

Tumour stem cells and drug resistance

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12 December 2020

The effect of Bcrp1 (Abcg2) on the in vivo pharmacokinetics and brain penetration of imatinib mesylate (Gleevec): implications for the use of breast cancer resistance protein and P-glycoprotein inhibitors to enable the brain penetration of imatinib

1 reference

12 December 2020

MicroRNA biogenesis and cancer

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12 December 2020

Gefitinib, an EGFR tyrosine kinase inhibitor, directly inhibits the function of P-glycoprotein in multidrug resistant cancer cells.

1 reference

12 December 2020

Involvement of BCRP (ABCG2) in the biliary excretion of pitavastatin

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12 December 2020

Imaging P-glycoprotein transport activity at the human blood-brain barrier with positron emission tomography

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12 December 2020

Mechanisms of drug resistance in cancer chemotherapy

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12 December 2020

Drug resistance in ovarian cancer: the emerging importance of gene transcription and spatio-temporal regulation of resistance

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12 December 2020

Multiple transporters affect the disposition of atorvastatin and its two active hydroxy metabolites: application of in vitro and ex situ systems

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12 December 2020

From methotrexate to pemetrexed and beyond. A review of the pharmacodynamic and clinical properties of antifolates

1 reference

12 December 2020

Breast cancer resistance protein (BCRP/ABCG2) transports fluoroquinolone antibiotics and affects their oral availability, pharmacokinetics, and milk secretion

1 reference

12 December 2020

Epigenetics as a mechanism driving polygenic clinical drug resistance

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12 December 2020

Mechanisms and strategies to overcome multiple drug resistance in cancer

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12 December 2020

Targeting multidrug resistance in cancer

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12 December 2020

Association of high-level MRP1 expression with poor clinical outcome in a large prospective study of primary neuroblastoma

1 reference

12 December 2020

Patterns of cancer incidence, mortality, and prevalence across five continents: defining priorities to reduce cancer disparities in different geographic regions of the world

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12 December 2020

Comparison of drug transporter levels in normal colon, colon cancer, and Caco-2 cells: impact on drug disposition and discovery.

1 reference

12 December 2020

The prognostic value of P-glycoprotein (ABCB) and breast cancer resistance protein (ABCG2) in adults with de novo acute myeloid leukemia with normal karyotype

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12 December 2020

Involvement of human micro-RNA in growth and response to chemotherapy in human cholangiocarcinoma cell lines

1 reference

12 December 2020

Role of BCRP 421C>A polymorphism on rosuvastatin pharmacokinetics in healthy Chinese males

1 reference

12 December 2020

Structure, function, expression, genomic organization, and single nucleotide polymorphisms of human ABCB1 (MDR1), ABCC (MRP), and ABCG2 (BCRP) efflux transporters

1 reference

12 December 2020

Pharmacogenetics of ABCG2 and adverse reactions to gefitinib

1 reference

12 December 2020

An inward-facing conformation of a putative metal-chelate-type ABC transporter

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12 December 2020

Portrait of multifaceted transporter, the multidrug resistance-associated protein 1 (MRP1/ABCC1).

1 reference

12 December 2020

Multiple paths to a drug resistance phenotype: mutations, translocations, deletions and amplification of coding genes or promoter regions, epigenetic changes and microRNAs

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12 December 2020

Hormonal interventions to prevent hormonal cancers: breast and prostate cancers

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12 December 2020

Multiple molecular mechanisms for multidrug resistance transporters

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12 December 2020

MET amplification leads to gefitinib resistance in lung cancer by activating ERBB3 signaling

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12 December 2020

Evaluation of drug-transporter interactions using in vitro and in vivo models

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12 December 2020

ABCG2 (breast cancer resistance protein/mitoxantrone resistance-associated protein) ATPase assay: a useful tool to detect drug-transporter interactions.

1 reference

12 December 2020

Understanding ribonucleotide reductase inactivation by gemcitabine.

1 reference

12 December 2020

Influence of breast cancer resistance protein (Abcg2) and p-glycoprotein (Abcb1a) on the transport of imatinib mesylate (Gleevec® ) across the mouse blood-brain barrier

1 reference

12 December 2020

ABC drug transporters as molecular targets for the prevention of multidrug resistance and drug-drug interactions.

1 reference

12 December 2020

Small interfering RNA in drug metabolism and transport

1 reference

12 December 2020

Erlotinib (Tarceva, OSI-774) antagonizes ATP-binding cassette subfamily B member 1 and ATP-binding cassette subfamily G member 2-mediated drug resistance

1 reference

12 December 2020

The breast cancer resistance protein (Bcrp1/Abcg2) limits fetal distribution of glyburide in the pregnant mouse: an Obstetric-Fetal Pharmacology Research Unit Network and University of Washington Specialized Center of Research Study

1 reference

12 December 2020

ABC multidrug transporters: structure, function and role in chemoresistance.

1 reference

12 December 2020

Phase III study of valspodar (PSC 833) combined with paclitaxel and carboplatin compared with paclitaxel and carboplatin alone in patients with stage IV or suboptimally debulked stage III epithelial ovarian cancer or primary peritoneal cancer

1 reference

12 December 2020

Drug-drug interactions mediated through P-glycoprotein: clinical relevance and in vitro-in vivo correlation using digoxin as a probe drug

1 reference

12 December 2020

Mutagenesis of the putative nucleotide-binding domains of the multidrug resistance associated protein (MRP). Analysis of the effect of these mutations on MRP mediated drug resistance and transport

1 reference

12 December 2020

An unexpected synergist role of P-glycoprotein and breast cancer resistance protein on the central nervous system penetration of the tyrosine kinase inhibitor lapatinib (N-{3-chloro-4-[(3-fluorobenzyl)oxy]phenyl}-6-[5-({[2-(methylsulfonyl)ethyl]amin

1 reference

12 December 2020

Vascular perfused segments of human intestine as a tool for drug absorption

1 reference

12 December 2020

Multidrug resistance in bacteria

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12 December 2020

MicroRNA-328 negatively regulates the expression of breast cancer resistance protein (BCRP/ABCG2) in human cancer cells

1 reference

12 December 2020

Structure of P-glycoprotein reveals a molecular basis for poly-specific drug binding

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12 December 2020

Nilotinib (AMN107, Tasigna) reverses multidrug resistance by inhibiting the activity of the ABCB1/Pgp and ABCG2/BCRP/MXR transporters

1 reference

12 December 2020

ABCG2 polymorphism markedly affects the pharmacokinetics of atorvastatin and rosuvastatin.

1 reference

12 December 2020

Regional differences in capillary density, perfusion rate, and P-glycoprotein activity: a quantitative analysis of regional drug exposure in the brain.

1 reference

12 December 2020

Importance of influx and efflux systems and xenobiotic metabolizing enzymes in intratumoral disposition of anticancer agents

1 reference

12 December 2020

Single nucleotide polymorphism in ABCG2 is associated with irinotecan-induced severe myelosuppression

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12 December 2020

Role of microRNAs in the regulation of drug metabolism and disposition

1 reference

12 December 2020

Regulation of gene expression in brain tissues of rats repeatedly treated by the highly abused opioid agonist, oxycodone: microarray profiling and gene mapping analysis

1 reference

12 December 2020

High-activity p-glycoprotein, multidrug resistance protein 2, and breast cancer resistance protein membrane vesicles prepared from transiently transfected human embryonic kidney 293-epstein-barr virus nuclear antigen cells.

1 reference

12 December 2020

Membrane transporters in drug development

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12 December 2020

Detoxification mechanisms and tumor cell resistance to anticancer drugs

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12 December 2020

Influence of blood-brain barrier efflux pumps on the distribution of vincristine in brain and brain tumors

1 reference

12 December 2020

Role of P-glycoprotein and breast cancer resistance protein-1 in the brain penetration and brain pharmacodynamic activity of the novel phosphatidylinositol 3-kinase inhibitor GDC-0941.

1 reference

12 December 2020

P-glycoprotein inhibition using valspodar (PSC-833) does not improve outcomes for patients younger than age 60 years with newly diagnosed acute myeloid leukemia: Cancer and Leukemia Group B study 19808

1 reference

12 December 2020

Nanoparticulate formulations for paclitaxel delivery across MDCK cell monolayer

1 reference

12 December 2020

Marine sponge-derived sipholane triterpenoids reverse P-glycoprotein (ABCB1)-mediated multidrug resistance in cancer cells

1 reference

12 December 2020

Zosuquidar, a novel modulator of P-glycoprotein, does not improve the outcome of older patients with newly diagnosed acute myeloid leukemia: a randomized, placebo-controlled trial of the Eastern Cooperative Oncology Group 3999

1 reference

12 December 2020

Emerging in vitro tools to evaluate cytochrome P450 and transporter-mediated drug-drug interactions

1 reference

12 December 2020

Drug-metabolizing enzyme, transporter, and nuclear receptor genetically modified mouse models

1 reference

12 December 2020

Lactoferrin-conjugated biodegradable polymersome holding doxorubicin and tetrandrine for chemotherapy of glioma rats

1 reference

12 December 2020

A pharmacodynamic study of docetaxel in combination with the P-glycoprotein antagonist tariquidar (XR9576) in patients with lung, ovarian, and cervical cancer.

1 reference

12 December 2020

Endocrine therapy of breast cancer

1 reference

12 December 2020

Breast cancer resistance protein BCRP/ABCG2 regulatory microRNAs (hsa-miR-328, -519c and -520h) and their differential expression in stem-like ABCG2+ cancer cells

1 reference

12 December 2020

Estrogen and androgen signaling in the pathogenesis of BPH.

1 reference

12 December 2020

Introduction: The prevention agenda

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12 December 2020

Microbial efflux pump inhibition: tactics and strategies

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12 December 2020

A critical analysis of the interplay between cytochrome P450 3A and P-glycoprotein: recent insights from knockout and transgenic mice

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12 December 2020

Drug-resistant malaria: molecular mechanisms and implications for public health

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12 December 2020

Development of a highly sensitive method using liquid chromatography-multiple reaction monitoring to quantify membrane P-glycoprotein in biological matrices and relationship to transport function

1 reference

12 December 2020

The controversial role of ABC transporters in clinical oncology.

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12 December 2020

Humanized transgenic mouse models for drug metabolism and pharmacokinetic research

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12 December 2020

Malaria drug resistance: new observations and developments

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12 December 2020

Use of baculovirus BacMam vectors for expression of ABC drug transporters in mammalian cells

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12 December 2020

Small molecule kinase inhibitors as anti-cancer therapeutics

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12 December 2020

GW583340 and GW2974, human EGFR and HER-2 inhibitors, reverse ABCG2- and ABCB1-mediated drug resistance.

1 reference

12 December 2020

A model for computer simulation of P-glycoprotein and transmembrane delta pH-mediated anthracycline transport in multidrug-resistant tumor cells

1 reference

12 December 2020

The function of Gp170, the multidrug resistance gene product, in rat liver canalicular membrane vesicles.

1 reference

12 December 2020

Internal duplication and homology with bacterial transport proteins in the mdr1 (P-glycoprotein) gene from multidrug-resistant human cells.

1 reference

12 December 2020

Purification of the 170- to 180-kilodalton membrane glycoprotein associated with multidrug resistance. 170- to 180-kilodalton membrane glycoprotein is an ATPase.

1 reference

12 December 2020

Mechanisms of multidrug resistance in HL60 cells: evidence that a surface membrane protein distinct from P-glycoprotein contributes to reduced cellular accumulation of drug.

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12 December 2020

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12 December 2020

Determinants of tumor blood flow: a review

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12 December 2020

Ethacrynic acid and piriprost as enhancers of cytotoxicity in drug resistant and sensitive cell lines.

1 reference

12 December 2020

ATP-dependent transport of vinblastine in vesicles from human multidrug-resistant cells

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12 December 2020

Mechanism of spontaneous inside-out vesiculation of red cell membranes

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12 December 2020

Kinetics of amino acid transport at the blood-brain barrier studied using an in situ brain perfusion technique

1 reference

12 December 2020

Transport of molecules in the tumor interstitium: a review

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12 December 2020

A novel chromosome abnormality in human neuroblastoma and antifolate-resistant Chinese hamster cell lives in culture

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12 December 2020

An in situ brain perfusion technique to study cerebrovascular transport in the rat.

1 reference

12 December 2020

Amplification of specific DNA sequences correlates with multi-drug resistance in Chinese hamster cells

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12 December 2020

Absence of the mdr1a P-Glycoprotein in mice affects tissue distribution and pharmacokinetics of dexamethasone, digoxin, and cyclosporin A.

1 reference

12 December 2020

Multidrug resistance and the role of P-glycoprotein knockout mice

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12 December 2020

P-glycoprotein Is Stably Inhibited by Vanadate-induced Trapping of Nucleotide at a Single Catalytic Site

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12 December 2020

Topoisomerase inhibitors. A review of their therapeutic potential in cancer

1 reference

12 December 2020

The effect of verapamil on the transport of peptides across the blood-brain barrier in rats: kinetic evidence for an apically polarized efflux mechanism

1 reference

12 December 2020

Reversal of multidrug resistance in murine fibrosarcoma cells by thioxanthene flupentixol

1 reference

12 December 2020

Disruption of the mouse mdr1a P-glycoprotein gene leads to a deficiency in the blood-brain barrier and to increased sensitivity to drugs

1 reference

12 December 2020

Pharmacological characterization of multidrug resistant MRP-transfected human tumor cells

1 reference

12 December 2020

Characterization of the adenosine triphosphatase activity of Chinese hamster P-glycoprotein.

1 reference

12 December 2020

Digoxin-cyclosporin A interaction: modulation of the multidrug transporter P-glycoprotein in the kidney

1 reference

12 December 2020

Role of P-glycoprotein in renal tubular secretion of digoxin in the isolated perfused rat kidney.

1 reference

12 December 2020

Topoisomerase inhibitors induce apoptosis in thymocytes

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12 December 2020

Selective paracellular permeability in two models of intestinal absorption: cultured monolayers of human intestinal epithelial cells and rat intestinal segments

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12 December 2020

Cisplatin and DNA repair in cancer chemotherapy

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12 December 2020

Effects of a selective inhibitor of the Abl tyrosine kinase on the growth of Bcr-Abl positive cells

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12 December 2020

P-glycoprotein in the blood-brain barrier of mice influences the brain penetration and pharmacological activity of many drugs

1 reference

12 December 2020

Inhibition of the intestinal digoxin absorption and exsorption by quinidine

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12 December 2020

Dose-dependent brain penetration of SDZ PSC 833, a novel multidrug resistance-reversing cyclosporin, in rats

1 reference

12 December 2020

Role of P-glycoprotein in the blood-brain transport of colchicine and vinblastine

1 reference

12 December 2020

Multidrug resistance in Lactococcus lactis: evidence for ATP-dependent drug extrusion from the inner leaflet of the cytoplasmic membrane.

1 reference

12 December 2020

MDR1 substrates/modulators protect against beta-estradiol-17beta-D-glucuronide cholestasis in rat liver

1 reference

12 December 2020

Normal viability and altered pharmacokinetics in mice lacking mdr1-type (drug-transporting) P-glycoproteins

1 reference

12 December 2020

Role of P-170 glycoprotein in colchicine brain uptake

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12 December 2020

Multidrug resistance in breast cancer: a meta-analysis of MDR1/gp170 expression and its possible functional significance.

1 reference

12 December 2020

Increased sensitivity to anticancer drugs and decreased inflammatory response in mice lacking the multidrug resistance-associated protein

1 reference

12 December 2020

Disruption of the murine MRP (multidrug resistance protein) gene leads to increased sensitivity to etoposide (VP-16) and increased levels of glutathione.

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12 December 2020

P-glycoprotein-mediated Hoechst 33342 transport out of the lipid bilayer.

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12 December 2020

Involvement of intestinal P-glycoprotein in the restricted absorption of methylprednisolone from rat small intestine

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12 December 2020

Role of P-glycoprotein as a secretory mechanism in quinidine absorption from rat small intestine

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12 December 2020

The ABC family of multidrug transporters in microorganisms

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12 December 2020

Characterization of the regional intestinal kinetics of drug efflux in rat and human intestine and in Caco-2 cells

1 reference

12 December 2020

Effect of multidrug resistance modulators on the hepatobiliary disposition of doxorubicin in the isolated perfused rat liver

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12 December 2020

A human placenta-specific ATP-binding cassette gene (ABCP) on chromosome 4q22 that is involved in multidrug resistance

1 reference

12 December 2020

A multidrug resistance transporter from human MCF-7 breast cancer cells

1 reference

12 December 2020

Molecular cloning of cDNAs which are highly overexpressed in mitoxantrone-resistant cells: demonstration of homology to ABC transport genes

1 reference

12 December 2020

A surface glycoprotein modulating drug permeability in Chinese hamster ovary cell mutants

1 reference

12 December 2020

Membrane fluidization by ether, other anesthetics, and certain agents abolishes P-glycoprotein ATPase activity and modulates efflux from multidrug-resistant cells.

1 reference

12 December 2020

10.2174/138161282005140214165212

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23688078%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23688078%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

PubMed publication ID

23688078

1 reference