(Q38736271)

6 September 2017

The rise and fall of insulin signaling in Alzheimer's disease (English)

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6 September 2017

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4

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6 September 2017

B Chami

1

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6 September 2017

A J Steel

series ordinal

2

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6 September 2017

S M De La Monte

series ordinal

3

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6 September 2017

16 February 2016

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6 September 2017

Metabolic Brain Disease

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6 September 2017

31

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6 September 2017

3

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6 September 2017

497-515

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https://scigraph.springernature.com/pub.10.1007/s11011-016-9806-1

6 September 2017

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cites work

Tyr(612) and Tyr(632) in human insulin receptor substrate-1 are important for full activation of insulin-stimulated phosphatidylinositol 3-kinase activity and translocation of GLUT4 in adipose cells

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12 December 2020

BDNF-mediated signal transduction is modulated by GSK3beta and mood stabilizing agents

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12 December 2020

Amyloid beta oligomers induce impairment of neuronal insulin receptors

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12 December 2020

GSK-3alpha regulates production of Alzheimer's disease amyloid-beta peptides

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12 December 2020

Glycogen synthase kinase-3 induces Alzheimer's disease-like phosphorylation of tau: generation of paired helical filament epitopes and neuronal localisation of the kinase.

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12 December 2020

Glycogen synthase kinase-3 beta phosphorylates tau protein at multiple sites in intact cells

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12 December 2020

Probing sporadic and familial Alzheimer's disease using induced pluripotent stem cells

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12 December 2020

Diabetics do not have increased Alzheimer-type pathology compared with age-matched control subjects. A retrospective postmortem immunocytochemical and histofluorescent study.

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12 December 2020

Mechanism of activation of protein kinase B by insulin and IGF-1

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12 December 2020

A pivotal role of GSK-3 in synaptic plasticity.

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12 December 2020

Evolution from pretangle neurons to neurofibrillary tangles monitored by thiazin red combined with Gallyas method and double immunofluorescence

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12 December 2020

Action of the diabetogenic drug streptozotocin on glycolytic and glycogenolytic metabolism in adult rat brain cortex and hippocampus.

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12 December 2020

Insulin receptor signaling regulates synapse number, dendritic plasticity, and circuit function in vivo

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12 December 2020

Insulin receptors are widely distributed in the central nervous system of the rat

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12 December 2020

Alternative pathway of insulin signalling in mice with targeted disruption of the IRS-1 gene.

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12 December 2020

Coupling of mammalian target of rapamycin with phosphoinositide 3-kinase signaling pathway regulates protein phosphatase 2A- and glycogen synthase kinase-3 -dependent phosphorylation of Tau

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12 December 2020

No effect of insulin on glucose blood-brain barrier transport and cerebral metabolism in humans.

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12 December 2020

Activation of Wnt/beta-catenin signaling increases insulin sensitivity through a reciprocal regulation of Wnt10b and SREBP-1c in skeletal muscle cells

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12 December 2020

Insulin modulates hippocampal activity-dependent synaptic plasticity in a N-methyl-d-aspartate receptor and phosphatidyl-inositol-3-kinase-dependent manner

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12 December 2020

Phosphorylation of Bax Ser184 by Akt regulates its activity and apoptosis in neutrophils

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12 December 2020

Presenilin regulates insulin signaling via a gamma-secretase-independent mechanism

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12 December 2020

Diabetes mellitus and risk of Alzheimer disease and decline in cognitive function

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12 December 2020

Intranasal insulin ameliorates tau hyperphosphorylation in a rat model of type 2 diabetes.

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12 December 2020

PTEN is recruited to the postsynaptic terminal for NMDA receptor-dependent long-term depression

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12 December 2020

Glycogen synthase kinase-3 and the Alzheimer-like state of microtubule-associated protein tau.

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12 December 2020

IRS-2 Deficiency impairs NMDA receptor-dependent long-term potentiation

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12 December 2020

Role of protein kinase B in Alzheimer's neurofibrillary pathology

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12 December 2020

Alzheimer's disease: the amyloid cascade hypothesis

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12 December 2020

Phosphorylation of the transcription factor forkhead family member FKHR by protein kinase B

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12 December 2020

Inhibition of the neuronal insulin receptor causes Alzheimer-like disturbances in oxidative/energy brain metabolism and in behavior in adult rats

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12 December 2020

Making insulin-deficient type 1 diabetic rodents thrive without insulin

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12 December 2020

The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics

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12 December 2020

Modulation of substrate transport to the brain

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12 December 2020

Demonstrated brain insulin resistance in Alzheimer's disease patients is associated with IGF-1 resistance, IRS-1 dysregulation, and cognitive decline

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12 December 2020

Dysregulation of insulin signaling, glucose transporters, O-GlcNAcylation, and phosphorylation of tau and neurofilaments in the brain: Implication for Alzheimer's disease

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12 December 2020

Presenilin mutations associated with Alzheimer disease cause defective intracellular trafficking of beta-catenin, a component of the presenilin protein complex

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12 December 2020

A mutation in APP protects against Alzheimer’s disease and age-related cognitive decline

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12 December 2020

Age-dependent accumulation of soluble amyloid beta (Abeta) oligomers reverses the neuroprotective effect of soluble amyloid precursor protein-alpha (sAPP(alpha)) by modulating phosphatidylinositol 3-kinase (PI3K)/Akt-GSK-3beta pathway in Alzheimer m

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12 December 2020

Amyloid-β as a modulator of synaptic plasticity

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12 December 2020

Regulation of insulin sensitivity by serine/threonine phosphorylation of insulin receptor substrate proteins IRS1 and IRS2

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12 December 2020

Stoichiometric coupling of brain glucose metabolism and glutamatergic neuronal activity

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12 December 2020

Glycogen synthase from rabbit skeletal muscle. Amino acid sequence at the sites phosphorylated by glycogen synthase kinase-3, and extension of the N-terminal sequence containing the site phosphorylated by phosphorylase kinase

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12 December 2020

Induced pluripotent stem cells as tools for disease modelling and drug discovery in Alzheimer's disease

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12 December 2020

Decreased autophosphorylation of the insulin receptor-kinase in streptozotocin-diabetic rats.

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12 December 2020

Phosphorylation of tau by fyn: implications for Alzheimer's disease.

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12 December 2020

Akt activity in Alzheimer's disease and other neurodegenerative disorders

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12 December 2020

PTEN: life as a tumor suppressor

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12 December 2020

Interplay between microtubule dynamics and intracellular organization

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12 December 2020

Neuronal hypertrophy in asymptomatic Alzheimer disease

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12 December 2020

Streptozotocin increases free fatty acids and decreases phospholipids in rat brain.

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12 December 2020

Direct regulation of the Akt proto-oncogene product by phosphatidylinositol-3,4-bisphosphate

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12 December 2020

The active form of glycogen synthase kinase-3beta is associated with granulovacuolar degeneration in neurons in Alzheimer's disease.

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12 December 2020

Activation of Akt/PKB, increased phosphorylation of Akt substrates and loss and altered distribution of Akt and PTEN are features of Alzheimer's disease pathology

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12 December 2020

Opposing Roles for Akt1 and Akt2 in Rac/Pak Signaling and Cell Migration

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12 December 2020

PSD-95 promotes Fyn-mediated tyrosine phosphorylation of the N-methyl-D-aspartate receptor subunit NR2A

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12 December 2020

Functional redundancy of GSK-3alpha and GSK-3beta in Wnt/beta-catenin signaling shown by using an allelic series of embryonic stem cell lines

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12 December 2020

Reducing endogenous tau ameliorates amyloid beta-induced deficits in an Alzheimer's disease mouse model

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12 December 2020

Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex

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12 December 2020

Parasympathetic and sympathetic control of the pancreas: a role for the suprachiasmatic nucleus and other hypothalamic centers that are involved in the regulation of food intake.

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12 December 2020

mTOR complex 2 regulates proper turnover of insulin receptor substrate-1 via the ubiquitin ligase subunit Fbw8.

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12 December 2020

Regulation of AMPA receptor-mediated synaptic transmission by clathrin-dependent receptor internalization

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12 December 2020

Glycogen synthase kinase-3beta phosphorylates Bax and promotes its mitochondrial localization during neuronal apoptosis.

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12 December 2020

Role for Akt3/protein kinase Bgamma in attainment of normal brain size

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12 December 2020

High dose insulin does not increase glucose transfer across the blood-brain barrier in humans: a re-evaluation.

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12 December 2020

Human blood-brain barrier insulin receptor

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12 December 2020

Concentrations of insulin and insulin receptors in the brain are independent of peripheral insulin levels. Studies of obese and streptozotocin-treated rodents

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12 December 2020

Phosphorylation of insulin receptor substrate 1 by glycogen synthase kinase 3 impairs insulin action

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12 December 2020

Diabetes mellitus and dementia

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12 December 2020

An anatomically comprehensive atlas of the adult human brain transcriptome

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12 December 2020

Tubulin-independent tau in Alzheimer's disease and cancer: implications for disease pathogenesis and treatment

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12 December 2020

PTEN, a negative regulator of PI3 kinase signalling, alters tau phosphorylation in cells by mechanisms independent of GSK-3.

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12 December 2020

Presenilin-1 is an unprimed glycogen synthase kinase-3beta substrate

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12 December 2020

Impaired insulin and insulin-like growth factor expression and signaling mechanisms in Alzheimer's disease--is this type 3 diabetes?

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12 December 2020

An integrative view of the role of oxidative stress, mitochondria and insulin in Alzheimer's disease

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12 December 2020

Relative resistance of Cdk5-phosphorylated CRMP2 to dephosphorylation.

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12 December 2020

Impact of diabetes on cognitive function and brain structure.

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12 December 2020

Dephosphorylation of tau protein and Alzheimer paired helical filaments by calcmeurin and phosphatase-2A

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12 December 2020

A human protein kinase Bgamma with regulatory phosphorylation sites in the activation loop and in the C-terminal hydrophobic domain

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12 December 2020

Insulin rescues amyloid beta-induced impairment of hippocampal long-term potentiation.

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12 December 2020

The kit receptor promotes cell survival via activation of PI 3-kinase and subsequent Akt-mediated phosphorylation of Bad on Ser136

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12 December 2020

Amyloid-β protein modulates insulin signaling in presynaptic terminals.

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12 December 2020

Amyloid plaque core protein in Alzheimer disease and Down syndrome

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12 December 2020

Mitochondria and neuronal activity.

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12 December 2020

Hypothalamic insulin signaling is required for inhibition of glucose production

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12 December 2020

Isomerase Pin1 stimulates dephosphorylation of tau protein at cyclin-dependent kinase (Cdk5)-dependent Alzheimer phosphorylation sites

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12 December 2020

What have we learned from the streptozotocin-induced animal model of sporadic Alzheimer's disease, about the therapeutic strategies in Alzheimer's research

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12 December 2020

Brain-derived neurotrophic factor induces long-term potentiation in intact adult hippocampus: requirement for ERK activation coupled to CREB and upregulation of Arc synthesis.

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12 December 2020

Hippocampal insulin resistance and cognitive dysfunction

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12 December 2020

Amyloid-beta peptide oligomers disrupt axonal transport through an NMDA receptor-dependent mechanism that is mediated by glycogen synthase kinase 3beta in primary cultured hippocampal neurons.

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12 December 2020

Insulin receptor substrate-2 deficiency impairs brain growth and promotes tau phosphorylation

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12 December 2020

Microtubule-associated protein tau (tau) is a major antigenic component of paired helical filaments in Alzheimer disease

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12 December 2020

Neuronal activity regulates the regional vulnerability to amyloid-β deposition

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12 December 2020

Secreted beta-amyloid precursor protein stimulates mitogen-activated protein kinase and enhances tau phosphorylation.

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12 December 2020

GSK3 in Alzheimer's disease: mind the isoforms

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12 December 2020

Alzheimer's disease is a synaptic failure

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12 December 2020

Microtubule-associated protein tau is essential for long-term depression in the hippocampus

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12 December 2020

Phosphorylation of tau by glycogen synthase kinase 3beta affects the ability of tau to promote microtubule self-assembly

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12 December 2020

Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease

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12 December 2020

PI3 kinase signaling is involved in Abeta-induced memory loss in Drosophila

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12 December 2020

The E-box binding factors Max/Mnt, MITF, and USF1 act coordinately with FoxO to regulate expression of proapoptotic and cell cycle control genes by phosphatidylinositol 3-kinase/Akt/glycogen synthase kinase 3 signaling

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12 December 2020

Increased risk of type 2 diabetes in Alzheimer disease

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12 December 2020

The insulin/Akt signaling pathway is targeted by intracellular beta-amyloid

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12 December 2020

Insulin resistance predicts medial temporal hypermetabolism in mild cognitive impairment conversion to Alzheimer disease

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12 December 2020

APP locus duplication causes autosomal dominant early-onset Alzheimer disease with cerebral amyloid angiopathy

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12 December 2020

Insulin metabolism and the risk of Alzheimer disease: the Rotterdam Study

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12 December 2020

The insulin receptor tyrosine kinase substrate p58/53 and the insulin receptor are components of CNS synapses

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12 December 2020

Brain-type glucose transporter (GLUT-1) is selectively localized to the blood-brain barrier. Studies with quantitative western blotting and in situ hybridization

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12 December 2020

Aβ(1-42) inhibition of LTP is mediated by a signaling pathway involving caspase-3, Akt1 and GSK-3β.

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12 December 2020

Pathology and pathogenesis of vascular cognitive impairment-a critical update

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12 December 2020

Soluble oligomers of amyloid Beta protein facilitate hippocampal long-term depression by disrupting neuronal glutamate uptake

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12 December 2020

A synaptic model of memory: long-term potentiation in the hippocampus

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12 December 2020

Neuropathological stageing of Alzheimer-related changes

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12 December 2020

A retroviral oncogene, akt, encoding a serine-threonine kinase containing an SH2-like region

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12 December 2020

Genetic ablation of tau mitigates cognitive impairment induced by type 1 diabetes

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12 December 2020

Understanding the pathogenesis of Alzheimer's disease: will RNA-Seq realize the promise of transcriptomics?

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12 December 2020

Insulin receptor isoforms and insulin receptor/insulin-like growth factor receptor hybrids in physiology and disease.

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12 December 2020

LTP inhibits LTD in the hippocampus via regulation of GSK3beta

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12 December 2020

Distribution of active glycogen synthase kinase 3beta (GSK-3beta) in brains staged for Alzheimer disease neurofibrillary changes.

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12 December 2020

Evidence for direct activation of mTORC2 kinase activity by phosphatidylinositol 3,4,5-trisphosphate

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12 December 2020

Insulin promotes dendritic spine and synapse formation by the PI3K/Akt/mTOR and Rac1 signaling pathways

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12 December 2020

Dysregulation of synaptic and extrasynaptic N-methyl-D-aspartate receptors induced by amyloid-β.

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12 December 2020

Inhibition of GSK3β-mediated BACE1 expression reduces Alzheimer-associated phenotypes

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12 December 2020

PI3K integrates the action of insulin and leptin on hypothalamic neurons

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12 December 2020

BDNF mRNA is decreased in the hippocampus of individuals with Alzheimer's disease

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12 December 2020

Insulin and the insulin receptor in experimental models of learning and memory.

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12 December 2020

Neurofibrillary tangles but not senile plaques parallel duration and severity of Alzheimer's disease

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12 December 2020

Regulation of cell death protease caspase-9 by phosphorylation

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12 December 2020

Defects in IGF-1 receptor, insulin receptor and IRS-1/2 in Alzheimer's disease indicate possible resistance to IGF-1 and insulin signalling

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12 December 2020

Hypothalamic sensing of circulating fatty acids is required for glucose homeostasis

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12 December 2020

National Institute on Aging-Alzheimer's Association guidelines for the neuropathologic assessment of Alzheimer's disease: a practical approach

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12 December 2020

The role of APP and BACE1 trafficking in APP processing and amyloid-β generation

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12 December 2020

Pancreatic Extracts in the Treatment of Diabetes Mellitus

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12 December 2020

Insulin-degrading enzyme as a downstream target of insulin receptor signaling cascade: implications for Alzheimer's disease intervention.

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12 December 2020

Tumor-suppressor PTEN affects tau phosphorylation, aggregation, and binding to microtubules

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12 December 2020

Anti-aβ therapeutics in Alzheimer's disease: the need for a paradigm shift

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12 December 2020

Identification and characterization of pleckstrin-homology-domain-dependent and isoenzyme-specific Akt inhibitors

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12 December 2020

Diabetes mellitus and risk of dementia: A meta-analysis of prospective observational studies

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12 December 2020

In vitro phosphorylation of the cytoplasmic domain of the amyloid precursor protein by glycogen synthase kinase-3beta

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12 December 2020

Contribution of cerebrovascular disease in autopsy confirmed neurodegenerative disease cases in the National Alzheimer's Coordinating Centre

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12 December 2020

Modulation of the glycogen synthase kinase-3 family by tyrosine phosphorylation

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12 December 2020

Leptin engages a hypothalamic neurocircuitry to permit survival in the absence of insulin

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12 December 2020

Vascular contributions to cognitive impairment and dementia: a statement for healthcare professionals from the american heart association/american stroke association

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12 December 2020

Insulin receptor mutation results in insulin resistance and hyperinsulinemia but does not exacerbate Alzheimer's-like phenotypes in mice.

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12 December 2020

Gain of function by phosphorylation in Presenilin 1-mediated regulation of insulin signaling

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12 December 2020

Alzheimer's beta-amyloid peptides compete for insulin binding to the insulin receptor

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12 December 2020

Neuroprotective effects of regulators of the glycogen synthase kinase-3beta signaling pathway in a transgenic model of Alzheimer's disease are associated with reduced amyloid precursor protein phosphorylation.

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12 December 2020

Abnormal Alzheimer-like phosphorylation of tau-protein by cyclin-dependent kinases cdk2 and cdk5

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12 December 2020

An anti-diabetes agent protects the mouse brain from defective insulin signaling caused by Alzheimer's disease- associated Aβ oligomers

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12 December 2020

Insulin in the brain: there and back again

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12 December 2020

The role of insulin receptor signaling in the brain

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12 December 2020

Role of brain insulin receptor in control of body weight and reproduction

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12 December 2020

Profound loss of layer II entorhinal cortex neurons occurs in very mild Alzheimer's disease.

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12 December 2020

Antioxidant capacity in rat brain after intracerebroventricular treatment with streptozotocin and alloxan--a preliminary study.

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12 December 2020

Impaired long-term potentiation, spatial learning, and hippocampal development in fyn mutant mice

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12 December 2020

Intracerebral streptozotocin model of type 3 diabetes: relevance to sporadic Alzheimer's disease.

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12 December 2020

Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B

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12 December 2020

Evidence that glycogen synthase kinase-3 isoforms have distinct substrate preference in the brain

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12 December 2020

mTOR complex 2 signaling and functions

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12 December 2020

Regulation of NMDA receptors by the tyrosine kinase Fyn

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12 December 2020

Insulin signaling in health and disease

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12 December 2020

GSK-3α/β kinases and amyloid production in vivo

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12 December 2020

Long-term depression in the CNS.

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12 December 2020

Akt phosphorylates and negatively regulates apoptosis signal-regulating kinase 1

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12 December 2020

Alzheimer's disease and Down's syndrome: Sharing of a unique cerebrovascular amyloid fibril protein

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12 December 2020

beta-catenin is a target for the ubiquitin-proteasome pathway

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12 December 2020

APP processing and synaptic function

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12 December 2020

Glycogen synthase kinase-3 from rabbit skeletal muscle. Separation from cyclic-AMP-dependent protein kinase and phosphorylase kinase

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12 December 2020

Phosphoinositide 3-kinases: a conserved family of signal transducers

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12 December 2020

Deficient brain insulin signalling pathway in Alzheimer's disease and diabetes

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12 December 2020

Knowing me, knowing you: can a knowledge of risk factors for Alzheimer's disease prove useful in understanding the pathogenesis of Parkinson's disease?

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12 December 2020

Stimulation of beta-amyloid precursor protein trafficking by insulin reduces intraneuronal beta-amyloid and requires mitogen-activated protein kinase signaling.

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12 December 2020

Therapeutic rescue of neurodegeneration in experimental type 3 diabetes: relevance to Alzheimer's disease

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12 December 2020

Dendritic function of tau mediates amyloid-beta toxicity in Alzheimer's disease mouse models

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12 December 2020

Glycogen synthase kinase-3 is associated with neuronal and glial hyperphosphorylated tau deposits in Alzheimer's disease, Pick's disease, progressive supranuclear palsy and corticobasal degeneration

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12 December 2020

Molecular genetics of Alzheimer's disease.

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12 December 2020

Regulation of Wnt/beta-catenin signaling by protein kinases

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12 December 2020

The role of IGF-1 receptor and insulin receptor signaling for the pathogenesis of Alzheimer's disease: from model organisms to human disease

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12 December 2020

Brain insulin system dysfunction in streptozotocin intracerebroventricularly treated rats generates hyperphosphorylated tau protein.

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12 December 2020

Beta-amyloid deposition in brains of subjects with diabetes

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12 December 2020

Kinetics and specificity of insulin uptake from plasma into cerebrospinal fluid

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12 December 2020

A complex interplay between Akt, TSC2 and the two mTOR complexes

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12 December 2020

Insulin and IGF-1 signalling: longevity, protein homoeostasis and Alzheimer's disease.

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12 December 2020

Dephosphorylation of microtubule-associated protein tau by protein phosphatase-1 and -2C and its implication in Alzheimer disease.

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12 December 2020

Activation of synaptic NMDA receptors induces membrane insertion of new AMPA receptors and LTP in cultured hippocampal neurons

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12 December 2020

Neurological phenotypes for Down syndrome across the life span

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12 December 2020

Inactivation of glycogen synthase kinase-3 beta by phosphorylation: new kinase connections in insulin and growth-factor signalling

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12 December 2020

PTEN, a widely known negative regulator of insulin/PI3K signaling, positively regulates neuronal insulin resistance

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12 December 2020

Diabetes mellitus and risk of developing Alzheimer disease: results from the Framingham Study.

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12 December 2020

The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor

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12 December 2020

Distribution, levels, and activity of glycogen synthase kinase-3 in the Alzheimer disease brain.

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12 December 2020

A kinesin signaling complex mediates the ability of GSK-3beta to affect mood-associated behaviors

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12 December 2020

p53 is a major component of the transcriptional and apoptotic program regulated by PI 3-kinase/Akt/GSK3 signaling

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12 December 2020

TSC2 is phosphorylated and inhibited by Akt and suppresses mTOR signalling

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12 December 2020

NGF is essential for hippocampal plasticity and learning

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12 December 2020

Desensitization of brain insulin receptor. Effect on glucose/energy and related metabolism.

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12 December 2020

Amyloid-β induces hepatic insulin resistance by activating JAK2/STAT3/SOCS-1 signaling pathway

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12 December 2020

Insights into the physiological function of the β-amyloid precursor protein: beyond Alzheimer's disease

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12 December 2020

Cerebral amyloid angiopathy in the brains of patients with Alzheimer's disease: the CERAD experience, Part XV.

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12 December 2020

Increased Aβ production prompts the onset of glucose intolerance and insulin resistance.

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12 December 2020

Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor

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12 December 2020

Non-Alzheimer neurodegenerative pathologies and their combinations are more frequent than commonly believed in the elderly brain: a community-based autopsy series.

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12 December 2020

PTEN levels in Alzheimer's disease medial temporal cortex

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12 December 2020

Glycogen synthase kinase 3β is identical to tau protein kinase I generating several epitopes of paired helical filaments

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12 December 2020

GDNF, NGF and BDNF as therapeutic options for neurodegeneration.

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12 December 2020

Peripheral hyperinsulinemia promotes tau phosphorylation in vivo

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12 December 2020

Brain-derived neurotrophic factor is reduced in Alzheimer's disease.

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12 December 2020

Role for neuronal insulin resistance in neurodegenerative diseases

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12 December 2020

Endogenous secreted amyloid precursor protein-alpha regulates hippocampal NMDA receptor function, long-term potentiation and spatial memory

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12 December 2020

Phases of A beta-deposition in the human brain and its relevance for the development of AD.

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12 December 2020

Glycogen synthase kinase-3 regulates mitochondrial outer membrane permeabilization and apoptosis by destabilization of MCL-1

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12 December 2020

Intranasal insulin as a treatment for Alzheimer's disease: a review of basic research and clinical evidence

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12 December 2020

Alzheimer's disease and diabetes: an integrative view of the role of mitochondria, oxidative stress, and insulin

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12 December 2020

Insulin-resistant brain state: the culprit in sporadic Alzheimer's disease?

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12 December 2020

Vascular complications of diabetes: mechanisms of injury and protective factors

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12 December 2020

Insulin transiently increases tau phosphorylation: involvement of glycogen synthase kinase-3beta and Fyn tyrosine kinase

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12 December 2020

Soluble Abeta inhibits specific signal transduction cascades common to the insulin receptor pathway.

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12 December 2020

Leptin enhances NMDA receptor function and modulates hippocampal synaptic plasticity.

1 reference

12 December 2020

Diabetes mellitus and the risk of dementia: The Rotterdam Study.

1 reference

12 December 2020

Permissive role of insulin in the expression of long-term potentiation in the hippocampus of immature rats.

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12 December 2020

Early detection of Alzheimer's disease using PiB and FDG PET

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12 December 2020

Distinct priming kinases contribute to differential regulation of collapsin response mediator proteins by glycogen synthase kinase-3 in vivo

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12 December 2020

Physiological roles for amyloid beta peptides

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12 December 2020

Receptor-mediated transport of insulin across endothelial cells

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12 December 2020

Calcium-mediated transient phosphorylation of tau and amyloid precursor protein followed by intraneuronal amyloid-beta accumulation.

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12 December 2020

Experimental diabetes mellitus exacerbates tau pathology in a transgenic mouse model of Alzheimer's disease

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12 December 2020

Effects of insulin on long-term potentiation in hippocampal slices from diabetic rats

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12 December 2020

Caspase-3 activation via mitochondria is required for long-term depression and AMPA receptor internalization.

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12 December 2020

Postsynaptic complexin controls AMPA receptor exocytosis during LTP

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12 December 2020

Physiological roles of PKB/Akt isoforms in development and disease

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12 December 2020

Amyloid-β/Fyn-induced synaptic, network, and cognitive impairments depend on tau levels in multiple mouse models of Alzheimer's disease.

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12 December 2020

A growing role for mTOR in promoting anabolic metabolism

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12 December 2020

Increased level of active GSK-3beta in Alzheimer's disease and accumulation in argyrophilic grains and in neurones at different stages of neurofibrillary degeneration.

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12 December 2020

Regulation of glucose transport by insulin: traffic control of GLUT4.

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12 December 2020

Mechanisms of disease: Pathway-selective insulin resistance and microvascular complications of diabetes

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12 December 2020

Diet-induced insulin resistance promotes amyloidosis in a transgenic mouse model of Alzheimer's disease

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12 December 2020

Protection of synapses against Alzheimer's-linked toxins: insulin signaling prevents the pathogenic binding of Abeta oligomers

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12 December 2020

Cooperative phosphorylation of the tumor suppressor phosphatase and tensin homologue (PTEN) by casein kinases and glycogen synthase kinase 3beta

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12 December 2020

Insulin and insulin-like growth factor-1 regulate tau phosphorylation in cultured human neurons.

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12 December 2020

Protein kinase B/Akt at a glance

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12 December 2020

Regulation of blood glucose by hypothalamic pyruvate metabolism

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12 December 2020

10.1007/S11011-016-9806-1

Identifiers

DOI

1 reference

Dimensions Publication ID

6 September 2017

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