(Q39456766)

12 September 2017

title

Epigenomic Consequences of Coding and Noncoding Driver Mutations (English)

1 reference

12 September 2017

Bin Tean Teh

5

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author name string

Xiaosai Yao

1

1 reference

12 September 2017

Manjie Xing

2

1 reference

12 September 2017

Wen Fong Ooi

3

1 reference

12 September 2017

Patrick Tan

4

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12 September 2017

language of work or name

1 reference

30 September 2016

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12 September 2017

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12 September 2017

volume

2

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12 September 2017

issue

10

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12 September 2017

page(s)

585-605

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12 September 2017

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Recurrent mutations in multiple components of the cohesin complex in myeloid neoplasms

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MED12, the mediator complex subunit 12 gene, is mutated at high frequency in uterine leiomyomas

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A histone H3 methyltransferase controls DNA methylation in Neurospora crassa

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Control of CpNpG DNA methylation by the KRYPTONITE histone H3 methyltransferase

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DNMT3A in haematological malignancies

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The DNA methyltransferases associate with HP1 and the SUV39H1 histone methyltransferase

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Suv39h-mediated histone H3 lysine 9 methylation directs DNA methylation to major satellite repeats at pericentric heterochromatin

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The histone methyltransferase SETDB1 and the DNA methyltransferase DNMT3A interact directly and localize to promoters silenced in cancer cells

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The Dnmt3a PWWP domain reads histone 3 lysine 36 trimethylation and guides DNA methylation

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Genomic profiling of DNA methyltransferases reveals a role for DNMT3B in genic methylation

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SWI/SNF-mutant cancers depend on catalytic and non-catalytic activity of EZH2

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Synthetic lethality by targeting EZH2 methyltransferase activity in ARID1A-mutated cancers

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An integrated encyclopedia of DNA elements in the human genome

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Integrative analysis of 111 reference human epigenomes

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Genomic maps and comparative analysis of histone modifications in human and mouse

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Distinct and predictive chromatin signatures of transcriptional promoters and enhancers in the human genome

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ChIP-seq analysis reveals distinct H3K27me3 profiles that correlate with transcriptional activity

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Pancreatic islet enhancer clusters enriched in type 2 diabetes risk-associated variants

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Epigenomic enhancer profiling defines a signature of colon cancer

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7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRECAN.2016.09.002

Identification of focally amplified lineage-specific super-enhancers in human epithelial cancers

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRECAN.2016.09.002

Activation of proto-oncogenes by disruption of chromosome neighborhoods.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRECAN.2016.09.002

CTCF/cohesin-binding sites are frequently mutated in cancer

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRECAN.2016.09.002

Insulator dysfunction and oncogene activation in IDH mutant gliomas

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRECAN.2016.09.002

Sensitive detection of chromatin-altering polymorphisms reveals autoimmune disease mechanisms

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRECAN.2016.09.002

Combinatorial effects of multiple enhancer variants in linkage disequilibrium dictate levels of gene expression to confer susceptibility to common traits

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRECAN.2016.09.002

Common genetic variants at the 11q13.3 renal cancer susceptibility locus influence binding of HIF to an enhancer of cyclin D1 expression.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRECAN.2016.09.002

Cell-of-origin chromatin organization shapes the mutational landscape of cancer

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRECAN.2016.09.002

Differential DNA repair underlies mutation hotspots at active promoters in cancer genomes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRECAN.2016.09.002

Nucleotide excision repair is impaired by binding of transcription factors to DNA.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRECAN.2016.09.002

Recurrent somatic mutations in regulatory regions of human cancer genomes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRECAN.2016.09.002

Initial sequencing and analysis of the human genome

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRECAN.2016.09.002

Abundant microsatellite polymorphism in Saccharomyces cerevisiae, and the different distributions of microsatellites in eight prokaryotes and S. cerevisiae, result from strong mutation pressures and a variety of selective forces

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRECAN.2016.09.002

Microsatellites in different eukaryotic genomes: survey and analysis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRECAN.2016.09.002

Functional genetic screens for enhancer elements in the human genome using CRISPR-Cas9.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRECAN.2016.09.002

Highly specific epigenome editing by CRISPR-Cas9 repressors for silencing of distal regulatory elements

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRECAN.2016.09.002

Epigenome editing by a CRISPR-Cas9-based acetyltransferase activates genes from promoters and enhancers.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRECAN.2016.09.002

Reduced local mutation density in regulatory DNA of cancer genomes is linked to DNA repair

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRECAN.2016.09.002

Chromatin organization is a major influence on regional mutation rates in human cancer cells.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRECAN.2016.09.002

Chromatin immunoprecipitation from fixed clinical tissues reveals tumor-specific enhancer profiles

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRECAN.2016.09.002

Single-cell ChIP-seq reveals cell subpopulations defined by chromatin state

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRECAN.2016.09.002

HDAC Inhibition Upregulates PD-1 Ligands in Melanoma and Augments Immunotherapy with PD-1 Blockade.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRECAN.2016.09.002

Genome-wide DNA methylation profiling using Infinium® assay

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRECAN.2016.09.002

Human DNA methylomes at base resolution show widespread epigenomic differences

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRECAN.2016.09.002

Chromosome-wide and promoter-specific analyses identify sites of differential DNA methylation in normal and transformed human cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRECAN.2016.09.002

ChIP-seq: advantages and challenges of a maturing technology

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRECAN.2016.09.002

Dynamic regulation of nucleosome positioning in the human genome

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRECAN.2016.09.002

Transposition of native chromatin for fast and sensitive epigenomic profiling of open chromatin, DNA-binding proteins and nucleosome position

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRECAN.2016.09.002

High-resolution mapping and characterization of open chromatin across the genome

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRECAN.2016.09.002

Using formaldehyde-assisted isolation of regulatory elements (FAIRE) to isolate active regulatory DNA.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRECAN.2016.09.002

Genome-wide mapping of nucleosome positioning and DNA methylation within individual DNA molecules

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRECAN.2016.09.002

Comprehensive genome-wide protein-DNA interactions detected at single-nucleotide resolution

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRECAN.2016.09.002

A SILAC-based DNA protein interaction screen that identifies candidate binding proteins to functional DNA elements

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRECAN.2016.09.002

Capturing chromosome conformation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRECAN.2016.09.002

Circular chromosome conformation capture (4C) uncovers extensive networks of epigenetically regulated intra- and interchromosomal interactions.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRECAN.2016.09.002

Comprehensive mapping of long-range interactions reveals folding principles of the human genome

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRECAN.2016.09.002

Analysis of hundreds of cis-regulatory landscapes at high resolution in a single, high-throughput experiment.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRECAN.2016.09.002

An oestrogen-receptor-α-bound human chromatin interactome

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRECAN.2016.09.002

Genome-wide quantitative enhancer activity maps identified by STARR-seq

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRECAN.2016.09.002

Highly parallel assays of tissue-specific enhancers in whole Drosophila embryos

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRECAN.2016.09.002

Inferring gene regulatory logic from high-throughput measurements of thousands of systematically designed promoters

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRECAN.2016.09.002

Exome sequencing identifies somatic mutations of DNA methyltransferase gene DNMT3A in acute monocytic leukemia

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRECAN.2016.09.002

Recurrent DNMT3A mutations in patients with myelodysplastic syndromes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRECAN.2016.09.002

Mutational analysis of DNMT3A gene in acute leukemias and common solid cancers

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRECAN.2016.09.002

TET2 and DNMT3A mutations in human T-cell lymphoma

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRECAN.2016.09.002

Mutation in TET2 in myeloid cancers

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRECAN.2016.09.002

Recurring mutations found by sequencing an acute myeloid leukemia genome

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRECAN.2016.09.002

IDH1 and IDH2 gene mutations identify novel molecular subsets within de novo cytogenetically normal acute myeloid leukemia: a Cancer and Leukemia Group B study

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRECAN.2016.09.002

An integrated genomic analysis of human glioblastoma multiforme

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRECAN.2016.09.002

IDH1 and IDH2 mutations in gliomas.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRECAN.2016.09.002

A trithorax-like gene is interrupted by chromosome 11q23 translocations in acute leukaemias

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRECAN.2016.09.002

Involvement of a homolog of Drosophila trithorax by 11q23 chromosomal translocations in acute leukemias

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRECAN.2016.09.002

The t(4;11) chromosome translocation of human acute leukemias fuses the ALL-1 gene, related to Drosophila trithorax, to the AF-4 gene

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRECAN.2016.09.002

Integrative genome analyses identify key somatic driver mutations of small-cell lung cancer

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRECAN.2016.09.002

Integrated genomic characterization of endometrial carcinoma

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRECAN.2016.09.002

The consensus coding sequences of human breast and colorectal cancers

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRECAN.2016.09.002

Integrated genomic analysis identifies recurrent mutations and evolution patterns driving the initiation and progression of follicular lymphoma

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRECAN.2016.09.002

Mutation of cancer driver MLL2 results in transcription stress and genome instability.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRECAN.2016.09.002

Systematic sequencing of renal carcinoma reveals inactivation of histone modifying genes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRECAN.2016.09.002

The histone mark H3K36me3 regulates human DNA mismatch repair through its interaction with MutSα

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRECAN.2016.09.002

Comprehensive molecular profiling of lung adenocarcinoma

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRECAN.2016.09.002

Mutations in SETD2 and genes affecting histone H3K36 methylation target hemispheric high-grade gliomas

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRECAN.2016.09.002

Identification of functional cooperative mutations of SETD2 in human acute leukemia

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRECAN.2016.09.002

Mutations in epigenetic regulators including SETD2 are gained during relapse in paediatric acute lymphoblastic leukaemia

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRECAN.2016.09.002

Somatic mutations at EZH2 Y641 act dominantly through a mechanism of selectively altered PRC2 catalytic activity, to increase H3K27 trimethylation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRECAN.2016.09.002

Mutation of A677 in histone methyltransferase EZH2 in human B-cell lymphoma promotes hypertrimethylation of histone H3 on lysine 27 (H3K27)

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRECAN.2016.09.002

EZH2 mutations are frequent and represent an early event in follicular lymphoma

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRECAN.2016.09.002

Inactivating mutations of the histone methyltransferase gene EZH2 in myeloid disorders

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRECAN.2016.09.002

A landscape of driver mutations in melanoma

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRECAN.2016.09.002

Histone demethylase JARID1C inactivation triggers genomic instability in sporadic renal cancer

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRECAN.2016.09.002

CREBBP mutations in relapsed acute lymphoblastic leukaemia

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRECAN.2016.09.002

Mutations truncating the EP300 acetylase in human cancers

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRECAN.2016.09.002

Germline mutation of INI1/SMARCB1 in familial schwannomatosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRECAN.2016.09.002

Small cell undifferentiated variant of hepatoblastoma: adverse clinical and molecular features similar to rhabdoid tumors

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRECAN.2016.09.002

SMARCB1/INI1 tumor suppressor gene is frequently inactivated in epithelioid sarcomas

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRECAN.2016.09.002

BAF180 is a critical regulator of p21 induction and a tumor suppressor mutated in breast cancer

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRECAN.2016.09.002

Mutational landscape and significance across 12 major cancer types

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRECAN.2016.09.002

CTCF Gene Mutations in Invasive Ductal Breast Cancer

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRECAN.2016.09.002

CTCF haploinsufficiency destabilizes DNA methylation and predisposes to cancer

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRECAN.2016.09.002

Frequent truncating mutations of STAG2 in bladder cancer

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRECAN.2016.09.002

Frequent inactivating mutations of STAG2 in bladder cancer are associated with low tumour grade and stage and inversely related to chromosomal copy number changes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRECAN.2016.09.002

Comprehensive molecular characterization of urothelial bladder carcinoma

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRECAN.2016.09.002

Histone H3.3. mutations drive pediatric glioblastoma through upregulation of MYCN.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRECAN.2016.09.002

BS69/ZMYND11 reads and connects histone H3.3 lysine 36 trimethylation-decorated chromatin to regulated pre-mRNA processing

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRECAN.2016.09.002

DAXX/ATRX, MEN1, and mTOR pathway genes are frequently altered in pancreatic neuroendocrine tumors

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRECAN.2016.09.002

An oncogenic MYB feedback loop drives alternate cell fates in adenoid cystic carcinoma.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.TRECAN.2016.09.002

10.1016/J.TRECAN.2016.09.002

7 January 2021

Identifiers

DOI

1 reference

release_qkilgcbb45fg3nrv5tzqu463wi

12 September 2017

Fatcat ID

0 references

1 reference