(Q37885217)

24 August 2017

1 reference

title

Role of Smads in TGFβ signaling (English)

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24 August 2017

2

1 reference

24 August 2017

Carl-Henrik Heldin

1

1 reference

24 August 2017

4 June 2011

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24 August 2017

Cell and Tissue Research

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24 August 2017

347

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24 August 2017

1

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24 August 2017

21-36

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https://scigraph.springernature.com/pub.10.1007/s00441-011-1190-x

24 August 2017

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cites work

TbetaRI phosphorylation of Smad2 on Ser465 and Ser467 is required for Smad2-Smad4 complex formation and signaling

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1190-X

A Mutant-p53/Smad complex opposes p63 to empower TGFbeta-induced metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1190-X

c-Ski acts as a transcriptional co-repressor in transforming growth factor-beta signaling through interaction with smads

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1190-X

Nuclear CDKs drive Smad transcriptional activation and turnover in BMP and TGF-beta pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1190-X

Jun N-terminal kinase 1 regulates epithelial-to-mesenchymal transition induced by TGF-beta1

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1190-X

TGF-beta1-induced expression of human Mdm2 correlates with late-stage metastatic breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1190-X

4E-BP1 is a target of Smad4 essential for TGFbeta-mediated inhibition of cell proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1190-X

Inhibition of the transforming growth factor beta (TGFbeta) pathway by interleukin-1beta is mediated through TGFbeta-activated kinase 1 phosphorylation of SMAD3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1190-X

Pre-EMTing metastasis? Recapitulation of morphogenetic processes in cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1190-X

Progressive tumor formation in mice with conditional deletion of TGF-beta signaling in head and neck epithelia is associated with activation of the PI3K/Akt pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1190-X

IKK(α) controls canonical TGF(ß)-SMAD signaling to regulate genes expressing SNAIL and SLUG during EMT in panc1 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1190-X

A reciprocal repression between ZEB1 and members of the miR-200 family promotes EMT and invasion in cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1190-X

Smad2 transduces common signals from receptor serine-threonine and tyrosine kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1190-X

Structural basis of heteromeric smad protein assembly in TGF-beta signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1190-X

Daxx mediates the small ubiquitin-like modifier-dependent transcriptional repression of Smad4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1190-X

Transforming growth factor beta-induced Smad1/5 phosphorylation in epithelial cells is mediated by novel receptor complexes and is essential for anchorage-independent growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1190-X

Smad3 protein levels are modulated by Ras activity and during the cell cycle to dictate transforming growth factor-beta responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1190-X

SMAD proteins control DROSHA-mediated microRNA maturation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1190-X

Smad proteins bind a conserved RNA sequence to promote microRNA maturation by Drosha

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1190-X

IKKalpha is a critical coregulator of a Smad4-independent TGFbeta-Smad2/3 signaling pathway that controls keratinocyte differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1190-X

Distinct endocytic pathways regulate TGF-β receptor signalling and turnover

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1190-X

SMAD4-dependent barrier constrains prostate cancer growth and metastatic progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1190-X

Microtubule binding to Smads may regulate TGF beta activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1190-X

Germ-layer specification and control of cell growth by Ectodermin, a Smad4 ubiquitin ligase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1190-X

FAM/USP9x, a deubiquitinating enzyme essential for TGFbeta signaling, controls Smad4 monoubiquitination

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1190-X

Smurf1 interacts with transforming growth factor-beta type I receptor through Smad7 and induces receptor degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1190-X

Association of v-ErbA with Smad4 disrupts TGF-beta signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1190-X

A kinase subdomain of transforming growth factor-beta (TGF-beta) type I receptor determines the TGF-beta intracellular signaling specificity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1190-X

Direct interaction of c-Myc with Smad2 and Smad3 to inhibit TGF-beta-mediated induction of the CDK inhibitor p15(Ink4B)

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1190-X

The oncoprotein c-ski functions as a direct antagonist of the transforming growth factor-{beta} type I receptor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1190-X

Integrating patterning signals: Wnt/GSK3 regulates the duration of the BMP/Smad1 signal

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1190-X

Ligand-dependent degradation of Smad3 by a ubiquitin ligase complex of ROC1 and associated proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1190-X

Ubiquitin ligase Nedd4L targets activated Smad2/3 to limit TGF-beta signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1190-X

Localized and reversible TGFbeta signalling switches breast cancer cells from cohesive to single cell motility

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1190-X

Activin receptor-like kinase (ALK)1 is an antagonistic mediator of lateral TGFbeta/ALK5 signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1190-X

An autocrine TGF-beta/ZEB/miR-200 signaling network regulates establishment and maintenance of epithelial-mesenchymal transition

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1190-X

Control of Smad7 stability by competition between acetylation and ubiquitination

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1190-X

Ligand-dependent ubiquitination of Smad3 is regulated by casein kinase 1 gamma 2, an inhibitor of TGF-beta signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1190-X

DPC4, a candidate tumor suppressor gene at human chromosome 18q21.1

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1190-X

Smad7 induces hepatic metastasis in colorectal cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1190-X

Epigenetic downregulation of human disabled homolog 2 switches TGF-beta from a tumor suppressor to a tumor promoter.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1190-X

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1190-X

TGF beta receptor internalization into EEA1-enriched early endosomes: role in signaling to Smad2

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1190-X

Hematopoiesis controlled by distinct TIF1gamma and Smad4 branches of the TGFbeta pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1190-X

Hypoxia-activated Smad3-specific dephosphorylation by PP2A.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1190-X

Mechanism of TGF-beta signaling to growth arrest, apoptosis, and epithelial-mesenchymal transition

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1190-X

The G protein-coupled receptor kinase-2 is a TGFbeta-inducible antagonist of TGFbeta signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1190-X

Role of Ras signaling in the induction of snail by transforming growth factor-beta.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1190-X

Molecular requirements for epithelial-mesenchymal transition during tumor progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1190-X

Emergence, development and diversification of the TGF-beta signalling pathway within the animal kingdom

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1190-X

TGFbeta signalling: a complex web in cancer progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1190-X

Estrogen inhibits transforming growth factor beta signaling by promoting Smad2/3 degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1190-X

Transforming growth factor beta1 induces nuclear export of inhibitory Smad7

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1190-X

Distinct oligomeric states of SMAD proteins in the transforming growth factor-beta pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1190-X

Deletion of Smad2 in mouse liver reveals novel functions in hepatocyte growth and differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1190-X

Role of Rho/ROCK and p38 MAP kinase pathways in transforming growth factor-beta-mediated Smad-dependent growth inhibition of human breast carcinoma cells in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1190-X

Smad7 inhibits transforming growth factor-beta family type i receptors through two distinct modes of interaction.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1190-X

New regulatory mechanisms of TGF-beta receptor function

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1190-X

Smad proteins exist as monomers in vivo and undergo homo- and hetero-oligomerization upon activation by serine/threonine kinase receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1190-X

Smad7 binds to Smurf2 to form an E3 ubiquitin ligase that targets the TGF beta receptor for degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1190-X

Integrin alpha3beta1-dependent beta-catenin phosphorylation links epithelial Smad signaling to cell contacts

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1190-X

Arkadia amplifies TGF-beta superfamily signalling through degradation of Smad7

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1190-X

Chromatin immunoprecipitation on microarray analysis of Smad2/3 binding sites reveals roles of ETS1 and TFAP2A in transforming growth factor beta signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1190-X

Negative regulation of transforming growth factor-beta (TGF-beta) signaling by WW domain-containing protein 1 (WWP1)

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1190-X

MicroRNA-155 is regulated by the transforming growth factor beta/Smad pathway and contributes to epithelial cell plasticity by targeting RhoA

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1190-X

The miR-200 family inhibits epithelial-mesenchymal transition and cancer cell migration by direct targeting of E-cadherin transcriptional repressors ZEB1 and ZEB2

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1190-X

Imaging transforming growth factor-beta signaling dynamics and therapeutic response in breast cancer bone metastasis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1190-X

TGFbeta induces SIK to negatively regulate type I receptor kinase signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1190-X

A mechanism of repression of TGFbeta/ Smad signaling by oncogenic Ras

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1190-X

NEDD4-2 (neural precursor cell expressed, developmentally down-regulated 4-2) negatively regulates TGF-beta (transforming growth factor-beta) signalling by inducing ubiquitin-mediated degradation of Smad2 and TGF-beta type I receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1190-X

Transforming growth factor-beta induces nuclear import of Smad3 in an importin-beta1 and Ran-dependent manner

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1190-X

The mechanism of nuclear export of Smad3 involves exportin 4 and Ran

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1190-X

Transforming growth factor-beta suppresses the ability of Ski to inhibit tumor metastasis by inducing its degradation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1190-X

TGFbeta prevents proteasomal degradation of the cyclin-dependent kinase inhibitor p27kip1 for cell cycle arrest

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1190-X

Sumoylation of Smad4, the Common Smad Mediator of Transforming Growth Factor-β Family Signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1190-X

Arkadia activates Smad3/Smad4-dependent transcription by triggering signal-induced SnoN degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1190-X

Ubiquitination and proteolysis of cancer-derived Smad4 mutants by SCFSkp2

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1190-X

Smurf2 is a ubiquitin E3 ligase mediating proteasome-dependent degradation of Smad2 in transforming growth factor-beta signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1190-X

PPM1A functions as a Smad phosphatase to terminate TGFbeta signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1190-X

TGFbeta-stimulated Smad1/5 phosphorylation requires the ALK5 L45 loop and mediates the pro-migratory TGFbeta switch

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1190-X

Axin is a scaffold protein in TGF-beta signaling that promotes degradation of Smad7 by Arkadia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1190-X

The L3 loop: a structural motif determining specific interactions between SMAD proteins and TGF-beta receptors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1190-X

The Ski oncoprotein interacts with the Smad proteins to repress TGFbeta signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1190-X

PARP-1 attenuates Smad-mediated transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1190-X

G1 cell-cycle control and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1190-X

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1190-X

Cyclin-dependent kinases regulate the antiproliferative function of Smads

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1190-X

Pin1 promotes transforming growth factor-beta-induced migration and invasion

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1190-X

Arkadia enhances Nodal/TGF-beta signaling by coupling phospho-Smad2/3 activity and turnover

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1190-X

A negative feedback control of transforming growth factor-beta signaling by glycogen synthase kinase 3-mediated Smad3 linker phosphorylation at Ser-204.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1190-X

Nuclear function of Smad7 promotes myogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1190-X

Differential ubiquitination defines the functional status of the tumor suppressor Smad4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1190-X

Negative regulation of TGFβ signaling by the kinase LKB1 and the scaffolding protein LIP1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1190-X

TGF-beta and HGF transmit the signals through JNK-dependent Smad2/3 phosphorylation at the linker regions

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1190-X

Non-Smad TGF-beta signals

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1190-X

Signaling networks guiding epithelial-mesenchymal transitions during embryogenesis and cancer progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1190-X

The regulation of TGFbeta signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1190-X

Arkadia induces degradation of SnoN and c-Ski to enhance transforming growth factor-beta signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1190-X

Downregulation of ZEB1 and overexpression of Smad7 contribute to resistance to TGF-beta1-mediated growth suppression in adult T-cell leukemia/lymphoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1190-X

Pin1 down-regulates transforming growth factor-beta (TGF-beta) signaling by inducing degradation of Smad proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1190-X

Identification of Smad7, a TGFbeta-inducible antagonist of TGF-beta signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1190-X

Notch signaling is necessary for epithelial growth arrest by TGF-beta

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1190-X

Transforming Growth Factor-β-mediated Signaling via the p38 MAP Kinase Pathway Activates Smad-dependent Transcription through SUMO-1 Modification of Smad4

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1190-X

Smad signaling is required to maintain epigenetic silencing during breast cancer progression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1190-X

Signaling by members of the TGF-beta family in vascular morphogenesis and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1190-X

Transforming growth factor beta-1 induces snail transcription factor in epithelial cell lines: mechanisms for epithelial mesenchymal transitions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1190-X

Snail, Zeb and bHLH factors in tumour progression: an alliance against the epithelial phenotype?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1190-X

Internalization-dependent and -independent requirements for transforming growth factor beta receptor signaling via the Smad pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1190-X

Smad2 and Smad3 have opposing roles in breast cancer bone metastasis by differentially affecting tumor angiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1190-X

Transforming growth factor beta-independent shuttling of Smad4 between the cytoplasm and nucleus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1190-X

The two faces of transforming growth factor beta in carcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1190-X

Phosphorylation of threonine 276 in Smad4 is involved in transforming growth factor-beta-induced nuclear accumulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1190-X

How the Smads regulate transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1190-X

Role of SARA (SMAD anchor for receptor activation) in maintenance of epithelial cell phenotype.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1190-X

Mathematical modeling identifies Smad nucleocytoplasmic shuttling as a dynamic signal-interpreting system

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1190-X

The novel E3 ubiquitin ligase Tiul1 associates with TGIF to target Smad2 for degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1190-X

TGFbeta influences Myc, Miz-1 and Smad to control the CDK inhibitor p15INK4b

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1190-X

Murine protein serine/threonine kinase 38 stimulates TGF-beta signaling in a kinase-dependent manner via direct phosphorylation of Smad proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1190-X

Requirement of HDAC6 for transforming growth factor-beta1-induced epithelial-mesenchymal transition.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1190-X

GADD34-PP1c recruited by Smad7 dephosphorylates TGFbeta type I receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1190-X

Mechanisms of TGF-beta signaling from cell membrane to the nucleus

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1190-X

Crystal structure of a Smad MH1 domain bound to DNA: insights on DNA binding in TGF-beta signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1190-X

TGF-β regulates isoform switching of FGF receptors and epithelial-mesenchymal transition

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1190-X

TGF-beta signalling is regulated by Schnurri-2-dependent nuclear translocation of CLIC4 and consequent stabilization of phospho-Smad2 and 3

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1190-X

The balance between acetylation and deacetylation controls Smad7 stability.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1190-X

The DNA binding activities of Smad2 and Smad3 are regulated by coactivator-mediated acetylation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1190-X

Sequential activation of NFAT and c-Myc transcription factors mediates the TGF-beta switch from a suppressor to a promoter of cancer cell proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1190-X

Phosphorylation of Ser465 and Ser467 in the C terminus of Smad2 mediates interaction with Smad4 and is required for transforming growth factor-beta signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1190-X

Negative feedback regulation of TGF-beta signaling by the SnoN oncoprotein

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1190-X

Chromosomal region maintenance 1 (CRM1)-dependent nuclear export of Smad ubiquitin regulatory factor 1 (Smurf1) is essential for negative regulation of transforming growth factor-beta signaling by Smad7

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1190-X

Epithelial-mesenchymal transitions in development and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1190-X

HMGA2 and Smads co-regulate SNAIL1 expression during induction of epithelial-to-mesenchymal transition

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1190-X

SARA, a FYVE domain protein that recruits Smad2 to the TGFbeta receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1190-X

Acetylation of Smad2 by the co-activator p300 regulates activin and transforming growth factor beta response

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1190-X

TAZ controls Smad nucleocytoplasmic shuttling and regulates human embryonic stem-cell self-renewal

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1190-X

A SNAIL1-SMAD3/4 transcriptional repressor complex promotes TGF-beta mediated epithelial-mesenchymal transition

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1190-X

ILEI: a cytokine essential for EMT, tumor formation, and late events in metastasis in epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1190-X

Jab1 antagonizes TGF-beta signaling by inducing Smad4 degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1190-X

Smad4 protein stability is regulated by ubiquitin ligase SCF beta-TrCP1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1190-X

Regulation of intracellular dynamics of Smad4 by its leucine-rich nuclear export signal

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1190-X

TMEPAI, a transmembrane TGF-beta-inducible protein, sequesters Smad proteins from active participation in TGF-beta signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1190-X

Inactivation of smad-transforming growth factor beta signaling by Ca(2+)-calmodulin-dependent protein kinase II

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1190-X

Crystal Structure of a Phosphorylated Smad2

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1190-X

Structural mechanism of Smad4 recognition by the nuclear oncoprotein Ski: insights on Ski-mediated repression of TGF-beta signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1190-X

Tgf-beta superfamily signaling in embryonic development and homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1190-X

Myc represses differentiation-induced p21CIP1 expression via Miz-1-dependent interaction with the p21 core promoter

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1190-X

Importin beta mediates nuclear translocation of Smad 3

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1190-X

An extended bipartite nuclear localization signal in Smad4 is required for its nuclear import and transcriptional activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1190-X

CHIP controls the sensitivity of transforming growth factor-beta signaling by modulating the basal level of Smad3 through ubiquitin-mediated degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1190-X

Smad2 nucleocytoplasmic shuttling by nucleoporins CAN/Nup214 and Nup153 feeds TGFbeta signaling complexes in the cytoplasm and nucleus

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1190-X

Msk is required for nuclear import of TGF-{beta}/BMP-activated Smads

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1190-X

Synergistic action of Smad4 and Pten in suppressing pancreatic ductal adenocarcinoma formation in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1190-X

Critical role of Smad2 in tumor suppression and transforming growth factor-beta-induced apoptosis of prostate epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1190-X

Preferential utilization of Imp7/8 in nuclear import of Smads

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1190-X

MTMR4 attenuates transforming growth factor beta (TGFbeta) signaling by dephosphorylating R-Smads in endosomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1190-X

Genetic programs of epithelial cell plasticity directed by transforming growth factor-beta

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1190-X

Tgfbr1 haploinsufficiency is a potent modifier of colorectal cancer development

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1190-X

Smad7 antagonizes transforming growth factor beta signaling in the nucleus by interfering with functional Smad-DNA complex formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1190-X

Regulation of Smad degradation and activity by Smurf2, an E3 ubiquitin ligase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1190-X

Tgfbeta signaling directly induces Arf promoter remodeling by a mechanism involving Smads 2/3 and p38 MAPK.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1190-X

A SMAD ubiquitin ligase targets the BMP pathway and affects embryonic pattern formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1190-X

Hepatic deletion of Smad7 in mouse leads to spontaneous liver dysfunction and aggravates alcoholic liver injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1190-X

Activation of Mps1 promotes transforming growth factor-beta-independent Smad signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00441-011-1190-X

10.1007/S00441-011-1190-X

21 January 2018

Identifiers

DOI

1 reference

24 August 2017

1 reference

PubMed ID

21643690