(Q90119301)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32144406%20AND%20SRC:MED&resulttype=core&format=json

11 April 2020

review article

1 reference

title

Cellular adaptation to hypoxia through hypoxia inducible factors and beyond (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32144406%20AND%20SRC:MED&resulttype=core&format=json

11 April 2020

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32144406%20AND%20SRC:MED&resulttype=core&format=json

11 April 2020

Navdeep S. Chandel

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32144406%20AND%20SRC:MED&resulttype=core&format=json

11 April 2020

M. Celeste Simon

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32144406%20AND%20SRC:MED&resulttype=core&format=json

11 April 2020

publication date

6 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32144406%20AND%20SRC:MED&resulttype=core&format=json

Nature Reviews Molecular Cell Biology

11 April 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32144406%20AND%20SRC:MED&resulttype=core&format=json

Hypoxia in health and disease

11 April 2020

cites work

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7 January 2021

Hypoxia-dependent regulation of inflammatory pathways in immune cells

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7 January 2021

Hypoxia-inducible factors in physiology and medicine

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7 January 2021

HIF1α and HIF2α: sibling rivalry in hypoxic tumour growth and progression

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7 January 2021

Oxygen sensing by metazoans: the central role of the HIF hydroxylase pathway

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7 January 2021

Protein Hydroxylation Catalyzed by 2-Oxoglutarate-dependent Oxygenases

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7 January 2021

Placental but not heart defects are associated with elevated hypoxia-inducible factor alpha levels in mice lacking prolyl hydroxylase domain protein 2

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7 January 2021

Asparagine hydroxylation of the HIF transactivation domain a hypoxic switch

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7 January 2021

The asparaginyl hydroxylase factor inhibiting HIF-1alpha is an essential regulator of metabolism

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7 January 2021

Proteomics-based identification of novel factor inhibiting hypoxia-inducible factor (FIH) substrates indicates widespread asparaginyl hydroxylation of ankyrin repeat domain-containing proteins.

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7 January 2021

Lack of activity of recombinant HIF prolyl hydroxylases (PHDs) on reported non-HIF substrates

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7 January 2021

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

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7 January 2021

Characterization of the human prolyl 4-hydroxylases that modify the hypoxia-inducible factor

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7 January 2021

Oxygen and mammalian cell culture: are we repeating the experiment of Dr. Ox?

1 reference

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

7 January 2021

Catalytic properties of the asparaginyl hydroxylase (FIH) in the oxygen sensing pathway are distinct from those of its prolyl 4-hydroxylases

1 reference

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

7 January 2021

Hypoxia-inducible factor 1 levels vary exponentially over a physiologically relevant range of O2 tension

1 reference

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7 January 2021

Multiple factors affecting cellular redox status and energy metabolism modulate hypoxia-inducible factor prolyl hydroxylase activity in vivo and in vitro

1 reference

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

7 January 2021

Redistribution of intracellular oxygen in hypoxia by nitric oxide: effect on HIF1alpha

1 reference

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

7 January 2021

Human CHCHD4 mitochondrial proteins regulate cellular oxygen consumption rate and metabolism and provide a critical role in hypoxia signaling and tumor progression

1 reference

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

7 January 2021

Reactive oxygen species generated at mitochondrial complex III stabilize hypoxia-inducible factor-1alpha during hypoxia: a mechanism of O2 sensing

1 reference

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

7 January 2021

Oxygen sensing requires mitochondrial ROS but not oxidative phosphorylation

1 reference

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

7 January 2021

Mitochondrial reactive oxygen species trigger hypoxia-induced transcription

1 reference

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

7 January 2021

Mitochondrial dysfunction resulting from loss of cytochrome c impairs cellular oxygen sensing and hypoxic HIF-alpha activation

1 reference

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

7 January 2021

Mitochondrial complex III is required for hypoxia-induced ROS production and cellular oxygen sensing

1 reference

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

7 January 2021

A chemical genomics screen highlights the essential role of mitochondria in HIF-1 regulation

1 reference

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

7 January 2021

ROS-dependent signal transduction

1 reference

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

7 January 2021

Paracrine Induction of HIF by Glutamate in Breast Cancer: EglN1 Senses Cysteine

1 reference

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

7 January 2021

Succinate dehydrogenase and fumarate hydratase: linking mitochondrial dysfunction and cancer.

1 reference

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

7 January 2021

Succinate links TCA cycle dysfunction to oncogenesis by inhibiting HIF-alpha prolyl hydroxylase

1 reference

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

7 January 2021

Accumulation of Krebs cycle intermediates and over-expression of HIF1alpha in tumours which result from germline FH and SDH mutations

1 reference

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

7 January 2021

Coupling Krebs cycle metabolites to signalling in immunity and cancer

1 reference

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

7 January 2021

L-2-Hydroxyglutarate production arises from noncanonical enzyme function at acidic pH

1 reference

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

7 January 2021

Acidic pH Is a Metabolic Switch for 2-Hydroxyglutarate Generation and Signaling.

1 reference

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

7 January 2021

Regulation of translation initiation in eukaryotes: mechanisms and biological targets

1 reference

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

7 January 2021

The mechanism of eukaryotic translation initiation and principles of its regulation

1 reference

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

7 January 2021

Translational control is a major contributor to hypoxia induced gene expression

1 reference

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

7 January 2021

The unfolded protein response: a novel component of the hypoxic stress response in tumors.

1 reference

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

7 January 2021

PERK mediates cell-cycle exit during the mammalian unfolded protein response

1 reference

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

7 January 2021

Perk-dependent translational regulation promotes tumor cell adaptation and angiogenesis in response to hypoxic stress

1 reference

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

7 January 2021

Regulation of protein synthesis by hypoxia via activation of the endoplasmic reticulum kinase PERK and phosphorylation of the translation initiation factor eIF2alpha

1 reference

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

7 January 2021

A novel hypoxia-inducible factor-independent hypoxic response regulating mammalian target of rapamycin and its targets.

1 reference

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

7 January 2021

Gene expression during acute and prolonged hypoxia is regulated by distinct mechanisms of translational control

1 reference

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

7 January 2021

Hypoxia inhibits protein synthesis through a 4E-BP1 and elongation factor 2 kinase pathway controlled by mTOR and uncoupled in breast cancer cells

1 reference

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

7 January 2021

Eukaryotic elongation factor 2 kinase, an unusual enzyme with multiple roles

1 reference

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

7 January 2021

Elongation Factor 2 Kinase Is Regulated by Proline Hydroxylation and Protects Cells during Hypoxia

1 reference

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

7 January 2021

Prolyl hydroxylase-dependent modulation of eukaryotic elongation factor 2 activity and protein translation under acute hypoxia

1 reference

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

7 January 2021

Optimal translational termination requires C4 lysyl hydroxylation of eRF1.

1 reference

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

7 January 2021

An integrated stress response regulates amino acid metabolism and resistance to oxidative stress

1 reference

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

7 January 2021

Regulated translation initiation controls stress-induced gene expression in mammalian cells

1 reference

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

7 January 2021

ER-stress-induced transcriptional regulation increases protein synthesis leading to cell death.

1 reference

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

7 January 2021

Multi-omics analysis identifies ATF4 as a key regulator of the mitochondrial stress response in mammals

1 reference

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

7 January 2021

A second look at cellular mRNA sequences said to function as internal ribosome entry sites

1 reference

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

7 January 2021

The role of IRES trans-acting factors in regulating translation initiation

1 reference

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

7 January 2021

Translation of vascular endothelial growth factor mRNA by internal ribosome entry: implications for translation under hypoxia

1 reference

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

7 January 2021

Internal initiation of translation directed by the 5'-untranslated region of the mRNA for eIF4G, a factor involved in the picornavirus-induced switch from cap-dependent to internal initiation

1 reference

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

7 January 2021

Hypoxia-mediated selective mRNA translation by an internal ribosome entry site-independent mechanism

1 reference

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

7 January 2021

Hypoxia-inducible factor-1alpha mRNA contains an internal ribosome entry site that allows efficient translation during normoxia and hypoxia

1 reference

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

7 January 2021

Translational control by 5'-untranslated regions of eukaryotic mRNAs

1 reference

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

7 January 2021

Translating the Untranslated Region.

1 reference

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

7 January 2021

Systemic Reprogramming of Translation Efficiencies on Oxygen Stimulus

1 reference

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

7 January 2021

An oxygen-regulated switch in the protein synthesis machinery

1 reference

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

7 January 2021

Cancer cells exploit eIF4E2-directed synthesis of hypoxia response proteins to drive tumor progression

1 reference

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

7 January 2021

Acid Suspends the Circadian Clock in Hypoxia through Inhibition of mTOR

1 reference

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

7 January 2021

Take the (RN)A-train: localization of mRNA to the endoplasmic reticulum

1 reference

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

7 January 2021

Hypoxia-induced gene expression results from selective mRNA partitioning to the endoplasmic reticulum.

1 reference

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

7 January 2021

The unfolded protein response: controlling cell fate decisions under ER stress and beyond

1 reference

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

7 January 2021

Endoplasmic reticulum stress signalling - from basic mechanisms to clinical applications

1 reference

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

7 January 2021

Peptides derived from the bifunctional kinase/RNase enzyme IRE1α modulate IRE1α activity and protect cells from endoplasmic reticulum stress.

1 reference

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

7 January 2021

Ligand-independent dimerization activates the stress response kinases IRE1 and PERK in the lumen of the endoplasmic reticulum.

1 reference

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

7 January 2021

IRE1 couples endoplasmic reticulum load to secretory capacity by processing the XBP-1 mRNA

1 reference

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

7 January 2021

IRE1-mediated unconventional mRNA splicing and S2P-mediated ATF6 cleavage merge to regulate XBP1 in signaling the unfolded protein response

1 reference

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

7 January 2021

Silencing of lipid metabolism genes through IRE1α-mediated mRNA decay lowers plasma lipids in mice.

1 reference

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

7 January 2021

IRE1α RNase-dependent lipid homeostasis promotes survival in Myc-transformed cancers.

1 reference

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

7 January 2021

Regulation of glucose homeostasis through a XBP-1-FoxO1 interaction

1 reference

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

7 January 2021

Inflammation Improves Glucose Homeostasis through IKKβ-XBP1s Interaction

1 reference

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

7 January 2021

Preventing oxidative stress: a new role for XBP1.

1 reference

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

7 January 2021

XBP1 promotes triple-negative breast cancer by controlling the HIF1α pathway

1 reference

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

7 January 2021

XBP1 is essential for survival under hypoxic conditions and is required for tumor growth.

1 reference

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

7 January 2021

Mammalian transcription factor ATF6 is synthesized as a transmembrane protein and activated by proteolysis in response to endoplasmic reticulum stress

1 reference

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

7 January 2021

ER stress induces cleavage of membrane-bound ATF6 by the same proteases that process SREBPs

1 reference

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

7 January 2021

Transcriptional induction of mammalian ER quality control proteins is mediated by single or combined action of ATF6alpha and XBP1

1 reference

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

7 January 2021

XBP1 mRNA is induced by ATF6 and spliced by IRE1 in response to ER stress to produce a highly active transcription factor

1 reference

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

7 January 2021

ATF6alpha optimizes long-term endoplasmic reticulum function to protect cells from chronic stress

1 reference

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

7 January 2021

ER stress regulation of ATF6 localization by dissociation of BiP/GRP78 binding and unmasking of Golgi localization signals

1 reference

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

7 January 2021

Adaptation to ER stress is mediated by differential stabilities of pro-survival and pro-apoptotic mRNAs and proteins

1 reference

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

7 January 2021

ER stress-regulated translation increases tolerance to extreme hypoxia and promotes tumor growth

1 reference

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

7 January 2021

PERK/eIF2α signaling protects therapy resistant hypoxic cells through induction of glutathione synthesis and protection against ROS.

1 reference

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

7 January 2021

Perk is essential for translational regulation and cell survival during the unfolded protein response

1 reference

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

7 January 2021

The steady-state kinetics of cytochrome c oxidation by cytochrome oxidase

1 reference

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

7 January 2021

Hypoxia. 2. Hypoxia regulates cellular metabolism

1 reference

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

7 January 2021

Molecular oxygen modulates cytochrome c oxidase function

1 reference

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

7 January 2021

HIF-1 regulates cytochrome oxidase subunits to optimize efficiency of respiration in hypoxic cells

1 reference

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

7 January 2021

Higd1a is a positive regulator of cytochrome c oxidase

1 reference

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

7 January 2021

Induction of the mitochondrial NDUFA4L2 protein by HIF-1α decreases oxygen consumption by inhibiting Complex I activity.

1 reference

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

7 January 2021

MicroRNA-210 controls mitochondrial metabolism during hypoxia by repressing the iron-sulfur cluster assembly proteins ISCU1/2

1 reference

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

7 January 2021

Hypoxia-regulated microRNA-210 modulates mitochondrial function and decreases ISCU and COX10 expression

1 reference

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

7 January 2021

miR-210 is overexpressed in late stages of lung cancer and mediates mitochondrial alterations associated with modulation of HIF-1 activity

1 reference

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

7 January 2021

Cellular and developmental control of O2 homeostasis by hypoxia-inducible factor 1 alpha

1 reference

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

7 January 2021

HIF-1-mediated expression of pyruvate dehydrogenase kinase: a metabolic switch required for cellular adaptation to hypoxia

1 reference

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

7 January 2021

HIF-1 mediates adaptation to hypoxia by actively downregulating mitochondrial oxygen consumption

1 reference

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

7 January 2021

Aspartate is a limiting metabolite for cancer cell proliferation under hypoxia and in tumours

1 reference

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

7 January 2021

HIGD1A Regulates Oxygen Consumption, ROS Production, and AMPK Activity during Glucose Deprivation to Modulate Cell Survival and Tumor Growth

1 reference

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

7 January 2021

CHCHD4 Regulates Intracellular Oxygenation and Perinuclear Distribution of Mitochondria

1 reference

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

7 January 2021

Mitochondrial composition and function under the control of hypoxia

1 reference

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

7 January 2021

Fine-tuning of Drp1/Fis1 availability by AKAP121/Siah2 regulates mitochondrial adaptation to hypoxia

1 reference

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

7 January 2021

A role for mitochondria in NLRP3 inflammasome activation

1 reference

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

7 January 2021

Mitochondrial outer-membrane protein FUNDC1 mediates hypoxia-induced mitophagy in mammalian cells

1 reference

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

7 January 2021

Mitochondria, oxidants, and aging

1 reference

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

7 January 2021

Low oxygen concentration extends the lifespan of cultured human diploid cells

1 reference

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

7 January 2021

Taking a "good" look at free radicals in the aging process

1 reference

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

7 January 2021

Mitochondrial reactive oxygen species trigger hypoxia-inducible factor-dependent extension of the replicative life span during hypoxia

1 reference

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

7 January 2021

Glucose restriction extends Caenorhabditis elegans life span by inducing mitochondrial respiration and increasing oxidative stress

1 reference

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

7 January 2021

Evolutionary conservation of the clk-1-dependent mechanism of longevity: loss of mclk1 increases cellular fitness and lifespan in mice

1 reference

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

7 January 2021

Mitochondrial oxygen sensing: regulation of hypoxia-inducible factor by mitochondrial generated reactive oxygen species

1 reference

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

7 January 2021

Inhibition of respiration extends C. elegans life span via reactive oxygen species that increase HIF-1 activity

1 reference

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

7 January 2021

Acute oxygen-sensing mechanisms

1 reference

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

7 January 2021

Mitochondrial Complex IV Subunit 4 Isoform 2 Is Essential for Acute Pulmonary Oxygen Sensing

1 reference

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

7 January 2021

Acute O2 sensing through HIF2α-dependent expression of atypical cytochrome oxidase subunits in arterial chemoreceptors

1 reference

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

7 January 2021

Oxygen Sensing by Arterial Chemoreceptors Depends on Mitochondrial Complex I Signaling.

1 reference

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

7 January 2021

Superoxide generated at mitochondrial complex III triggers acute responses to hypoxia in the pulmonary circulation.

1 reference

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

7 January 2021

Impaired hypoxic pulmonary vasoconstriction in a mouse model of Leigh syndrome

1 reference

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

7 January 2021

Energy costs of ion pumping by animal tissues

1 reference

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

7 January 2021

Role of ubiquitination in Na,K-ATPase regulation during lung injury

1 reference

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

7 January 2021

Hypoxic activation of AMPK is dependent on mitochondrial ROS but independent of an increase in AMP/ATP ratio

1 reference

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

7 January 2021

Hypoxia triggers AMPK activation through reactive oxygen species-mediated activation of calcium release-activated calcium channels

1 reference

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

7 January 2021

Hypoxia leads to Na,K-ATPase downregulation via Ca(2+) release-activated Ca(2+) channels and AMPK activation

1 reference

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

7 January 2021

5'-AMP-activated protein kinase (AMPK) is induced by low-oxygen and glucose deprivation conditions found in solid-tumor microenvironments

1 reference

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

7 January 2021

AMPK: Mechanisms of Cellular Energy Sensing and Restoration of Metabolic Balance

1 reference

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

7 January 2021

Hypoxia-induced energy stress regulates mRNA translation and cell growth

1 reference

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

7 January 2021

Suppressors of superoxide production from mitochondrial complex III

1 reference

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

7 January 2021

Complex III releases superoxide to both sides of the inner mitochondrial membrane

1 reference

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

7 January 2021

Broad AOX expression in a genetically tractable mouse model does not disturb normal physiology

1 reference

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

7 January 2021

Metabolic adaptation of cancer and immune cells mediated by hypoxia-inducible factors

1 reference

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

7 January 2021

Oxygen availability and metabolic adaptations

1 reference

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

7 January 2021

Oxygen availability and metabolic reprogramming in cancer.

1 reference

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

7 January 2021

Lactate Metabolism in Human Lung Tumors

1 reference

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

7 January 2021

Metabolite Exchange between Mammalian Organs Quantified in Pigs

1 reference

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

7 January 2021

Hypoxia-induced switch in SNAT2/SLC38A2 regulation generates endocrine resistance in breast cancer.

1 reference

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

7 January 2021

Hypoxic regulation of glutamine metabolism through HIF1 and SIAH2 supports lipid synthesis that is necessary for tumor growth

1 reference

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

7 January 2021

HIF-1-mediated suppression of acyl-CoA dehydrogenases and fatty acid oxidation is critical for cancer progression.

1 reference

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

7 January 2021

Hypoxic and Ras-transformed cells support growth by scavenging unsaturated fatty acids from lysophospholipids

1 reference

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

7 January 2021

Dysregulated mTORC1 renders cells critically dependent on desaturated lipids for survival under tumor-like stress

1 reference

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

7 January 2021

Lipid desaturation - the next step in targeting lipogenesis in cancer?

1 reference

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

7 January 2021

Fatty acid-induced beta cell apoptosis: a link between obesity and diabetes

1 reference

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

7 January 2021

HIF2α-Dependent Lipid Storage Promotes Endoplasmic Reticulum Homeostasis in Clear-Cell Renal Cell Carcinoma.

1 reference

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

7 January 2021

Triglycerides Promote Lipid Homeostasis during Hypoxic Stress by Balancing Fatty Acid Saturation

1 reference

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

7 January 2021

Serine Synthesis Helps Hypoxic Cancer Stem Cells Regulate Redox.

1 reference

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

7 January 2021

Development by self-digestion: molecular mechanisms and biological functions of autophagy

1 reference

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

7 January 2021

The machinery of macroautophagy

1 reference

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

7 January 2021

Autophagy and Tumor Metabolism

1 reference

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

7 January 2021

Hypoxia-induced autophagy: cell death or cell survival?

1 reference

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

7 January 2021

Autophagy in human health and disease

1 reference

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

7 January 2021

Role of tumor and host autophagy in cancer metabolism

1 reference

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

7 January 2021

Mitochondrial autophagy is an HIF-1-dependent adaptive metabolic response to hypoxia

1 reference

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

7 January 2021

Hypoxia-induced autophagy is mediated through hypoxia-inducible factor induction of BNIP3 and BNIP3L via their BH3 domains

1 reference

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

7 January 2021

Hypoxia signalling in cancer and approaches to enforce tumour regression

1 reference

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

7 January 2021

Hypoxia induces autophagic cell death in apoptosis-competent cells through a mechanism involving BNIP3.

1 reference

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

7 January 2021

Bnip3L is induced by p53 under hypoxia, and its knockdown promotes tumor growth

1 reference

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

7 January 2021

Atypical BH3-domains of BNIP3 and BNIP3L lead to autophagy in hypoxia.

1 reference

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

7 January 2021

Hypoxia-induced BNIP3 expression and mitophagy: in vivo comparison of the rat and the hypoxia-tolerant mole rat, Spalax ehrenbergi.

1 reference

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

7 January 2021

Tumor suppressor functions of BNIP3 and mitophagy

1 reference

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

7 January 2021

The Role of the PERK/eIF2α/ATF4/CHOP Signaling Pathway in Tumor Progression During Endoplasmic Reticulum Stress

1 reference

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

7 January 2021

The AMPK signalling pathway coordinates cell growth, autophagy and metabolism

1 reference

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

7 January 2021

AMPK and autophagy get connected.

1 reference

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

7 January 2021

ULK1 induces autophagy by phosphorylating Beclin-1 and activating VPS34 lipid kinase.

1 reference

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

7 January 2021

Phosphorylation of ULK1 (hATG1) by AMP-activated protein kinase connects energy sensing to mitophagy

1 reference

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

7 January 2021

Metabolic profiling of hypoxic cells revealed a catabolic signature required for cell survival

1 reference

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

7 January 2021

Reciprocal regulation of endocytosis and metabolism

1 reference

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

7 January 2021

The GLUT4 glucose transporter

1 reference

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

7 January 2021

Glucose transport and sensing in the maintenance of glucose homeostasis and metabolic harmony

1 reference

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

7 January 2021

Endocytosis, recycling, and regulated exocytosis of glucose transporter 4.

1 reference

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

7 January 2021

Kinetic evidence for unique regulation of GLUT4 trafficking by insulin and AMP-activated protein kinase activators in L6 myotubes

1 reference

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

7 January 2021

A role for AMP-activated protein kinase in contraction- and hypoxia-regulated glucose transport in skeletal muscle

1 reference

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

7 January 2021

Hypoxia in Combination With Muscle Contraction Improves Insulin Action and Glucose Metabolism in Human Skeletal Muscle via the HIF-1α Pathway.

1 reference

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

7 January 2021

Long-Term Chronic Intermittent Hypobaric Hypoxia Induces Glucose Transporter (GLUT4) Translocation Through AMP-Activated Protein Kinase (AMPK) in the Soleus Muscle in Lean Rats

1 reference

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

7 January 2021

The differential role of Hif1β/Arnt and the hypoxic response in adipose function, fibrosis, and inflammation

1 reference

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

7 January 2021

Uses and abuses of macropinocytosis

1 reference

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

7 January 2021

Macropinocytosis: A Metabolic Adaptation to Nutrient Stress in Cancer

1 reference

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

7 January 2021

Macropinocytosis of protein is an amino acid supply route in Ras-transformed cells

1 reference

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

7 January 2021

The Utilization of Extracellular Proteins as Nutrients Is Suppressed by mTORC1.

1 reference

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

7 January 2021

Human pancreatic cancer tumors are nutrient poor and tumor cells actively scavenge extracellular protein

1 reference

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

7 January 2021

Regulation of chromatin and gene expression by metabolic enzymes and metabolites

1 reference

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

7 January 2021

Targeting renal cell carcinoma with a HIF-2 antagonist.

1 reference

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

7 January 2021

On-target efficacy of a HIF-2α antagonist in preclinical kidney cancer models

1 reference

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

7 January 2021

HIF-2 Complex Dissociation, Target Inhibition, and Acquired Resistance with PT2385, a First-in-Class HIF-2 Inhibitor, in Patients with Clear Cell Renal Cell Carcinoma

1 reference

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

7 January 2021

HIF prolyl hydroxylase inhibitors for the treatment of renal anaemia and beyond

1 reference

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

7 January 2021

Leigh Syndrome Mouse Model Can Be Rescued by Interventions that Normalize Brain Hyperoxia, but Not HIF Activation

1 reference

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

7 January 2021

Hypoxia Rescues Frataxin Loss by Restoring Iron Sulfur Cluster Biogenesis

1 reference

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

7 January 2021

Hypoxia-induced angiogenesis: good and evil

1 reference

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

7 January 2021

Endothelial cell metabolism in health and disease: impact of hypoxia.

1 reference

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

7 January 2021

Hypoxia and metabolic adaptation of cancer cells

1 reference

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

7 January 2021

Intratumoral pO2 predicts survival in advanced cancer of the uterine cervix

1 reference

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

7 January 2021

Oxygen status of malignant tumors: pathogenesis of hypoxia and significance for tumor therapy

1 reference

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

7 January 2021

Hypoxia-dependent modification of collagen networks promotes sarcoma metastasis.

1 reference

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

7 January 2021

Selective tumor hypoxia targeting by hypoxia-activated prodrug TH-302 inhibits tumor growth in preclinical models of cancer.

1 reference

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

7 January 2021

The role of hypoxia-activated prodrugs in cancer therapy

1 reference

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

7 January 2021

Molecular Pathways: Hypoxia-Activated Prodrugs in Cancer Therapy

1 reference

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

7 January 2021

Chromatin and oxygen sensing in the context of JmjC histone demethylases

1 reference

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

7 January 2021

Histone demethylase KDM6A directly senses oxygen to control chromatin and cell fate

1 reference

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

7 January 2021

Hypoxia induces rapid changes to histone methylation and reprograms chromatin

1 reference

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

7 January 2021

Conserved N-terminal cysteine dioxygenases transduce responses to hypoxia in animals and plants

1 reference

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

7 January 2021

Oxygen sensing in plants is mediated by an N-end rule pathway for protein destabilization.

1 reference

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

7 January 2021

Homeostatic response to hypoxia is regulated by the N-end rule pathway in plants

1 reference

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

7 January 2021

Plant cysteine oxidases control the oxygen-dependent branch of the N-end-rule pathway.

1 reference

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

7 January 2021

Regulation of mTOR function in response to hypoxia by REDD1 and the TSC1/TSC2 tumor suppressor complex

1 reference

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

7 January 2021

Regulation of mTOR and cell growth in response to energy stress by REDD1.

1 reference

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

7 January 2021

The mTOR Targets 4E-BP1/2 Restrain Tumor Growth and Promote Hypoxia Tolerance in PTEN-driven Prostate Cancer.

1 reference

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

7 January 2021

Hypoxia-induced regulation of mTOR signaling by miR-7 targeting REDD1

1 reference

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

7 January 2021

PML inhibits HIF-1alpha translation and neoangiogenesis through repression of mTOR

1 reference

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

7 January 2021

The Rag GTPases bind raptor and mediate amino acid signaling to mTORC1

1 reference

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

7 January 2021

Bnip3 mediates the hypoxia-induced inhibition on mammalian target of rapamycin by interacting with Rheb

1 reference

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

7 January 2021

mTORC1 signaling under hypoxic conditions is controlled by ATM-dependent phosphorylation of HIF-1α.

1 reference

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

7 January 2021

TSC2 regulates VEGF through mTOR-dependent and -independent pathways

1 reference

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

7 January 2021

Regulation of hypoxia-inducible factor 1alpha expression and function by the mammalian target of rapamycin.

1 reference

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

7 January 2021

Hypoxia-inducible factor determines sensitivity to inhibitors of mTOR in kidney cancer

1 reference

https://api.crossref.org/works/10.1038%2FS41580-020-0227-Y

7 January 2021

French Society of EEG and Clinical Neurophysiology. Paris, 5 October 1988. Abstracts

1 reference

12 December 2020

The oxygen dependence of mitochondrial oxidative phosphorylation measured by a new optical method for measuring oxygen concentration.

1 reference

12 December 2020

The Effect of Examiner Error on the Extent of Recorded Fluctuations in Marginal Gingivitis

1 reference

12 December 2020

1 reference

12 December 2020

Tumor oxygenation predicts for the likelihood of distant metastases in human soft tissue sarcoma

1 reference

12 December 2020

Complexes containing activating transcription factor (ATF)/cAMP-responsive-element-binding protein (CREB) interact with the CCAAT/enhancer-binding protein (C/EBP)-ATF composite site to regulate Gadd153 expression during the stress response

1 reference

12 December 2020

The respiratory chain and oxidative phosphorylation

1 reference

12 December 2020

Perinuclear mitochondrial clustering creates an oxidant-rich nuclear domain required for hypoxia-induced transcription

1 reference

12 December 2020

Loss of HIF-1α impairs GLUT4 translocation and glucose uptake by the skeletal muscle cells.

1 reference

12 December 2020

PPARα Protein Expression Was Increased by Four Weeks of Intermittent Hypoxic Training via AMPKα2-Dependent Manner in Mouse Skeletal Muscle

1 reference

12 December 2020

Simultaneous Hypoxia and Low Extracellular pH Suppress Overall Metabolic Rate and Protein Synthesis In Vitro

1 reference

12 December 2020

Oxidative Dimerization of PHD2 is Responsible for its Inactivation and Contributes to Metabolic Reprogramming via HIF-1α Activation

1 reference

12 December 2020

Phosphorylation of ULK1 affects autophagosome fusion and links chaperone-mediated autophagy to macroautophagy

1 reference

12 December 2020

Effects of four weeks intermittent hypoxia intervention on glucose homeostasis, insulin sensitivity, GLUT4 translocation, insulin receptor phosphorylation, and Akt activity in skeletal muscle of obese mice with type 2 diabetes

1 reference

12 December 2020

10.1038/S41580-020-0227-Y

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32144406%20AND%20SRC:MED&resulttype=core&format=json

11 April 2020

1 reference