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HIF hydroxylase pathways in cardiovascular physiology and medicine
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Europe PubMed Central
title
HIF hydroxylase pathways in cardiovascular physiology and medicine
(English)
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PubMed
main subject
circulatory system
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based on heuristic
inferred from title
physiology
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author
Peter J. Ratcliffe
series ordinal
2
object named as
P. J. Ratcliffe
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Crossref
author name string
T. Bishop
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1
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Crossref
language of work or name
English
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PubMed
publication date
19 June 2015
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PubMed
published in
Circulation Research
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stated in
PubMed
volume
117
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stated in
PubMed
issue
1
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stated in
PubMed
page(s)
65-79
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PubMed
cites work
Cardiopulmonary function in two human disorders of the hypoxia-inducible factor (HIF) pathway: von Hippel-Lindau disease and HIF-2alpha gain-of-function mutation
1 reference
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PubMed Central
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21 March 2017
Natural selection on EPAS1 (HIF2alpha) associated with low hemoglobin concentration in Tibetan highlanders
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PubMed Central
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21 March 2017
HIF prolyl-hydroxylase 2 is the key oxygen sensor setting low steady-state levels of HIF-1alpha in normoxia
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PubMed Central
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21 March 2017
FIH-1 is an asparaginyl hydroxylase enzyme that regulates the transcriptional activity of hypoxia-inducible factor
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PubMed Central
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21 March 2017
Cardiac malformations, adrenal agenesis, neural crest defects and exencephaly in mice lacking Cited2, a new Tfap2 co-activator
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21 March 2017
FIH-1: a novel protein that interacts with HIF-1alpha and VHL to mediate repression of HIF-1 transcriptional activity
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PubMed Central
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21 March 2017
A conserved family of prolyl-4-hydroxylases that modify HIF
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PubMed Central
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21 March 2017
C. elegans EGL-9 and mammalian homologs define a family of dioxygenases that regulate HIF by prolyl hydroxylation
1 reference
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PubMed Central
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21 March 2017
HIFalpha targeted for VHL-mediated destruction by proline hydroxylation: implications for O2 sensing
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PubMed Central
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21 March 2017
The hypoxia-responsive transcription factor EPAS1 is essential for catecholamine homeostasis and protection against heart failure during embryonic development
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PubMed Central
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21 March 2017
Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension
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PubMed Central
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21 March 2017
A nuclear factor induced by hypoxia via de novo protein synthesis binds to the human erythropoietin gene enhancer at a site required for transcriptional activation
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21 March 2017
Erythropoietin: powerful protection of ischemic and post-ischemic brain
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PubMed Central
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21 March 2017
Birth prevalence of congenital heart disease worldwide: a systematic review and meta-analysis
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21 March 2017
Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4501273
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21 March 2017
Characterization of the human prolyl 4-hydroxylases that modify the hypoxia-inducible factor
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4501273
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21 March 2017
Hypoxia-inducible factor (HIF) asparagine hydroxylase is identical to factor inhibiting HIF (FIH) and is related to the cupin structural family
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4501273
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21 March 2017
Mutation of von Hippel-Lindau tumour suppressor and human cardiopulmonary physiology
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PubMed Central
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21 March 2017
Asparagine hydroxylation of the HIF transactivation domain a hypoxic switch
1 reference
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PubMed Central
reference URL
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21 March 2017
Molecular mechanisms of action and therapeutic uses of pharmacological inhibitors of HIF-prolyl 4-hydroxylases for treatment of ischemic diseases
1 reference
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PubMed Central
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21 March 2017
Genetic evidence for high-altitude adaptation in Tibet
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PubMed Central
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21 March 2017
Hypoxia-inducible factor-dependent degeneration, failure, and malignant transformation of the heart in the absence of the von Hippel-Lindau protein
1 reference
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PubMed Central
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21 March 2017
The effect of hypoxia in development
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PubMed Central
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21 March 2017
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PubMed Central
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7 April 2017
Differential function of the prolyl hydroxylases PHD1, PHD2, and PHD3 in the regulation of hypoxia-inducible factor
1 reference
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PubMed Central
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21 March 2017
Cellular and developmental control of O2 homeostasis by hypoxia-inducible factor 1 alpha
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PubMed Central
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21 March 2017
Placental but not heart defects are associated with elevated hypoxia-inducible factor alpha levels in mice lacking prolyl hydroxylase domain protein 2
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PubMed Central
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21 March 2017
Loss of HIF-2alpha and inhibition of VEGF impair fetal lung maturation, whereas treatment with VEGF prevents fatal respiratory distress in premature mice
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PubMed Central
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21 March 2017
Defective vascularization of HIF-1alpha-null embryos is not associated with VEGF deficiency but with mesenchymal cell death
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PubMed Central
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21 March 2017
Impaired physiological responses to chronic hypoxia in mice partially deficient for hypoxia-inducible factor 1alpha
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21 March 2017
Potent and Selective Triazole-Based Inhibitors of the Hypoxia-Inducible Factor Prolyl-Hydroxylases with Activity in the Murine Brain
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21 March 2017
The hypoxia-inducible transcription factor pathway regulates oxygen sensing in the simplest animal, Trichoplax adhaerens
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PubMed Central
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21 March 2017
Abnormal sympathoadrenal development and systemic hypotension in PHD3-/- mice
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21 March 2017
Cardia bifida, defective heart development and abnormal neural crest migration in embryos lacking hypoxia-inducible factor-1alpha
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21 March 2017
Multiple organ pathology, metabolic abnormalities and impaired homeostasis of reactive oxygen species in Epas1-/- mice
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21 March 2017
The transcription factor EPAS-1/hypoxia-inducible factor 2alpha plays an important role in vascular remodeling
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PubMed Central
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21 March 2017
Building the mammalian heart from two sources of myocardial cells
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7 April 2017
Differential roles of hypoxia-inducible factor 1alpha (HIF-1alpha) and HIF-2alpha in hypoxic gene regulation
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7 April 2017
Depletion of PHD3 protects heart from ischemia/reperfusion injury by inhibiting cardiomyocyte apoptosis
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28 September 2017
Oxygen-dependent hydroxylation by FIH regulates the TRPV3 ion channel
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28 September 2017
Mimicking hypoxia to treat anemia: HIF-stabilizer BAY 85-3934 (Molidustat) stimulates erythropoietin production without hypertensive effects
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28 September 2017
A genetic mechanism for Tibetan high-altitude adaptation
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28 September 2017
HIF and pulmonary vascular responses to hypoxia
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28 September 2017
Regulation of hypoxia-induced pulmonary hypertension by vascular smooth muscle hypoxia-inducible factor-1α.
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28 September 2017
Hypoxia-inducible factor 1 is required for remote ischemic preconditioning of the heart
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28 September 2017
HIF isoforms in the skin differentially regulate systemic arterial pressure
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28 September 2017
Tibetans living at sea level have a hyporesponsive hypoxia-inducible factor system and blunted physiological responses to hypoxia
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PubMed Central
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28 September 2017
Inhibition of hypoxia-inducible factor prolyl hydroxylase domain oxygen sensors: tricking the body into mounting orchestrated survival and repair responses
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28 September 2017
Oxygen sensing, hypoxia-inducible factors, and disease pathophysiology
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28 September 2017
Activation of hypoxia response in endothelial cells contributes to ischemic cardioprotection
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28 September 2017
Erythrocytosis: the HIF pathway in control.
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28 September 2017
Erythrocytosis and pulmonary hypertension in a mouse model of human HIF2A gain of function mutation
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PubMed Central
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28 September 2017
Hypoxia-inducible factor-1α in pulmonary artery smooth muscle cells lowers vascular tone by decreasing myosin light chain phosphorylation
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PubMed Central
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28 September 2017
Activation of hypoxia-inducible factor-1 in pulmonary arterial smooth muscle cells by endothelin-1.
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28 September 2017
Oxygen sensing and hypoxia signalling pathways in animals: the implications of physiology for cancer
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28 September 2017
HIF-1α is a protective factor in conditional PHD2-deficient mice suffering from severe HIF-2α-induced excessive erythropoiesis
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28 September 2017
Decreased serum glucose and glycosylated hemoglobin levels in patients with Chuvash polycythemia: a role for HIF in glucose metabolism
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28 September 2017
Adaptive and maladaptive cardiorespiratory responses to continuous and intermittent hypoxia mediated by hypoxia-inducible factors 1 and 2.
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28 September 2017
A cell-autonomous role of Cited2 in controlling myocardial and coronary vascular development
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28 September 2017
Hypoxia-inducible factor stabilizers and other small-molecule erythropoiesis-stimulating agents in current and preventive doping analysis
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28 September 2017
Hypoxia inducible factor-1: its potential role in cerebral ischemia
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28 September 2017
TRPA1 underlies a sensing mechanism for O2.
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28 September 2017
Humans at high altitude: hypoxia and fetal growth
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28 September 2017
High-resolution genome-wide mapping of HIF-binding sites by ChIP-seq.
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28 September 2017
Differential sensitivity of hypoxia inducible factor hydroxylation sites to hypoxia and hydroxylase inhibitors
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28 September 2017
Hypoxia-inducible factor 2α (HIF-2α) heterozygous-null mice exhibit exaggerated carotid body sensitivity to hypoxia, breathing instability, and hypertension
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28 September 2017
Cardiomyocyte-specific prolyl-4-hydroxylase domain 2 knock out protects from acute myocardial ischemic injury
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28 September 2017
Hypoxia. 4. Hypoxia and ion channel function
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28 September 2017
Disruption of hypoxia-inducible transcription factor-prolyl hydroxylase domain-1 (PHD-1-/-) attenuates ex vivo myocardial ischemia/reperfusion injury through hypoxia-inducible factor-1α transcription factor and its target genes in mice.
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PubMed Central
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28 September 2017
The HIF pathway and erythrocytosis
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PubMed Central
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28 September 2017
Erythropoietin molecules to treat acute ischemic stroke: a translational dilemma!
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28 September 2017
Loss of Hypoxia-Inducible Factor Prolyl Hydroxylase Activity in Cardiomyocytes Phenocopies Ischemic Cardiomyopathy
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28 September 2017
Hypoxia-inducible factor 1: Regulator of mitochondrial metabolism and mediator of ischemic preconditioning
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28 September 2017
Physiological and biochemical aspects of hydroxylations and demethylations catalyzed by human 2-oxoglutarate oxygenases
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28 September 2017
Chronic inhibition of hypoxia-inducible factor prolyl 4-hydroxylase improves ventricular performance, remodeling, and vascularity after myocardial infarction in the rat.
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28 September 2017
Hypoxia and fetal heart development.
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28 September 2017
Hypoxia inducible factor 1 (HIF-1) and cardioprotection
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4501273
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28 September 2017
Prolyl hydroxylase domain-containing protein inhibitors as stabilizers of hypoxia-inducible factor: small molecule-based therapeutics for anemia
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4501273
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28 September 2017
Conditional HIF-1alpha expression produces a reversible cardiomyopathy
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4501273
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28 September 2017
The von Hippel-Lindau Chuvash mutation promotes pulmonary hypertension and fibrosis in mice.
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28 September 2017
Hearts of hypoxia-inducible factor prolyl 4-hydroxylase-2 hypomorphic mice show protection against acute ischemia-reperfusion injury
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4501273
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28 September 2017
The role of hypoxia in development of the Mammalian embryo
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4501273
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28 September 2017
Effects of iron supplementation and depletion on hypoxic pulmonary hypertension: two randomized controlled trials
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4501273
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28 September 2017
Interdependence of hypoxic and innate immune responses
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4501273
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28 September 2017
Prolyl hydroxylase inhibition attenuates post-ischemic cardiac injury via induction of endoplasmic reticulum stress genes.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4501273
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28 September 2017
Endothelial deletion of hypoxia-inducible factor-2alpha (HIF-2alpha) alters vascular function and tumor angiogenesis
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4501273
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28 September 2017
Inhibition of oxygen sensors as a therapeutic strategy for ischaemic and inflammatory disease
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4501273
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28 September 2017
The increase in pulmonary arterial pressure caused by hypoxia depends on iron status
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4501273
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28 September 2017
Proteomics-based identification of novel factor inhibiting hypoxia-inducible factor (FIH) substrates indicates widespread asparaginyl hydroxylation of ankyrin repeat domain-containing proteins.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4501273
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28 September 2017
Short hairpin RNA interference therapy for ischemic heart disease
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4501273
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28 September 2017
Abnormal heart development and lung remodeling in mice lacking the hypoxia-inducible factor-related basic helix-loop-helix PAS protein NEPAS
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4501273
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28 September 2017
Oxygen sensing by ion channels
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4501273
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28 September 2017
Role of hypoxia in the evolution and development of the cardiovascular system
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4501273
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28 September 2017
Activation of hypoxia-inducible factor-1 via prolyl-4 hydoxylase-2 gene silencing attenuates acute inflammatory responses in postischemic myocardium
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4501273
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28 September 2017
Mechanisms of acute oxygen sensing by the carotid body: lessons from genetically modified animals
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4501273
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28 September 2017
The role of k+ channels in determining pulmonary vascular tone, oxygen sensing, cell proliferation, and apoptosis: implications in hypoxic pulmonary vasoconstriction and pulmonary arterial hypertension
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4501273
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28 September 2017
Mouse model for noninvasive imaging of HIF prolyl hydroxylase activity: assessment of an oral agent that stimulates erythropoietin production
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4501273
retrieved
28 September 2017
HIF-1 activation attenuates postischemic myocardial injury: role for heme oxygenase-1 in modulating microvascular chemokine generation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4501273
retrieved
28 September 2017
Differentiating the functional role of hypoxia-inducible factor (HIF)-1alpha and HIF-2alpha (EPAS-1) by the use of RNA interference: erythropoietin is a HIF-2alpha target gene in Hep3B and Kelly cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4501273
retrieved
28 September 2017
Role of myocardial hypoxia in the remodeling of the embryonic avian cardiac outflow tract
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4501273
retrieved
28 September 2017
Heterozygous deficiency of hypoxia-inducible factor-2alpha protects mice against pulmonary hypertension and right ventricular dysfunction during prolonged hypoxia
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4501273
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28 September 2017
Disruption of oxygen homeostasis underlies congenital Chuvash polycythemia
1 reference
stated in
PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4501273
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28 September 2017
Expression of hypoxia-inducible factor-1alpha and -2alpha in hypoxic and ischemic rat kidneys
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4501273
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28 September 2017
Determination of hypoxic region by hypoxia marker in developing mouse embryos in vivo: a possible signal for vessel development
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4501273
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28 September 2017
Inducible operation of the erythropoietin 3' enhancer in multiple cell lines: evidence for a widespread oxygen-sensing mechanism
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4501273
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28 September 2017
Desferrioxamine induces erythropoietin gene expression and hypoxia-inducible factor 1 DNA-binding activity: implications for models of hypoxia signal transduction
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4501273
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28 September 2017
Chemotransduction in the carotid body: K+ current modulated by PO2 in type I chemoreceptor cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4501273
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28 September 2017
Hypoxia inducible factor 1 mediates hypoxia-induced TRPC expression and elevated intracellular Ca2+ in pulmonary arterial smooth muscle cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4501273
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31 May 2018
Pre- and post-conditional inhibition of prolyl-4-hydroxylase domain enzymes protects the heart from an ischemic insult.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4501273
retrieved
28 November 2018
HIF-1 reduces ischaemia-reperfusion injury in the heart by targeting the mitochondrial permeability transition pore.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4501273
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28 November 2018
Vulnerability of the developing heart to oxygen deprivation as a cause of congenital heart defects
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4501273
retrieved
28 November 2018
Gene-environment interaction demonstrates the vulnerability of the embryonic heart.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4501273
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28 November 2018
Cardiovascular toxicity of epoetin-alfa in patients with chronic kidney disease
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4501273
retrieved
28 November 2018
Carotid body hyperplasia and enhanced ventilatory responses to hypoxia in mice with heterozygous deficiency of PHD2.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4501273
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28 November 2018
A mechanism for gene-environment interaction in the etiology of congenital scoliosis.
1 reference
stated in
PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4501273
retrieved
28 November 2018
Unfavourable consequences of chronic cardiac HIF-1α stabilization
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4501273
retrieved
28 November 2018
The protective effect of prolyl-hydroxylase inhibition against renal ischaemia requires application prior to ischaemia but is superior to EPO treatment.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4501273
retrieved
28 November 2018
Iron deficiency is common in idiopathic pulmonary arterial hypertension
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4501273
retrieved
28 November 2018
Attenuation of myocardial injury by postconditioning: role of hypoxia inducible factor-1alpha
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4501273
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28 November 2018
Essential role of developmentally activated hypoxia-inducible factor 1alpha for cardiac morphogenesis and function.
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4501273
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28 November 2018
Autosomal dominant erythrocytosis and pulmonary arterial hypertension associated with an activating HIF2 alpha mutation.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4501273
retrieved
28 November 2018
Hypoxia-inducible factor-1 is central to cardioprotection: a new paradigm for ischemic preconditioning
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4501273
retrieved
28 November 2018
Complete loss of ischaemic preconditioning-induced cardioprotection in mice with partial deficiency of HIF-1 alpha
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4501273
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28 November 2018
Peruvian contributions to the study on human reproduction at high altitude: from the chronicles of the Spanish conquest to the present
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4501273
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28 November 2018
Partial rescue of defects in Cited2-deficient embryos by HIF-1alpha heterozygosity.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4501273
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28 November 2018
HIF prolyl hydroxylases in the rat; organ distribution and changes in expression following hypoxia and coronary artery ligation.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4501273
retrieved
28 November 2018
Stabilization of hypoxia inducible factor rather than modulation of collagen metabolism improves cardiac function after acute myocardial infarction in rats
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4501273
retrieved
28 November 2018
Hypoxia-inducible factor 1-alpha reduces infarction and attenuates progression of cardiac dysfunction after myocardial infarction in the mouse
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4501273
retrieved
28 November 2018
Hypoxia inducible factor-1 activation by prolyl 4-hydroxylase-2 gene silencing attenuates myocardial ischemia reperfusion injury
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4501273
retrieved
28 November 2018
Deferoxamine induces prolonged cardiac preconditioning via accumulation of oxygen radicals
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4501273
retrieved
28 November 2018
Hypoxia-responsive signaling regulates the apoptosis-dependent remodeling of the embryonic avian cardiac outflow tract
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4501273
retrieved
28 November 2018
Cobalt chloride induces delayed cardiac preconditioning in mice through selective activation of HIF-1alpha and AP-1 and iNOS signaling.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4501273
retrieved
28 November 2018
Persistent induction of HIF-1alpha and -2alpha in cardiomyocytes and stromal cells of ischemic myocardium
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4501273
retrieved
28 November 2018
Hearts from rodents exposed to intermittent hypoxia or erythropoietin are protected against ischemia-reperfusion injury
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4501273
retrieved
28 November 2018
Widespread hypoxia-inducible expression of HIF-2alpha in distinct cell populations of different organs.
1 reference
stated in
PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4501273
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28 November 2018
Desferrioxamine elevates pulmonary vascular resistance in humans: potential for involvement of HIF-1.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4501273
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28 November 2018
Inhibition of collagen synthesis with prolyl 4-hydroxylase inhibitor improves left ventricular function and alters the pattern of left ventricular dilatation after myocardial infarction
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4501273
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28 November 2018
Expression of ARNT, ARNT2, HIF1 alpha, HIF2 alpha and Ah receptor mRNAs in the developing mouse.
1 reference
stated in
PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4501273
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28 November 2018
Experimental production of congenital anomalies; timing and degree of anoxia as factors causing fetal deaths and congenital anomalies in the mouse
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stated in
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12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Endothelin-1, vascular endothelial growth factor and systolic pulmonary artery pressure in patients with Chuvash polycythemia
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/26089364
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
HIF-1 alpha expression is associated with an atheromatous inflammatory plaque phenotype and upregulated in activated macrophages
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/26089364
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Role of hypoxia inducible factor-1α in remote limb ischemic preconditioning
1 reference
stated in
PubMed
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https://pubmed.ncbi.nlm.nih.gov/26089364
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Signaling hypoxia by hypoxia-inducible factor protein hydroxylases: a historical overview and future perspectives
1 reference
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https://pubmed.ncbi.nlm.nih.gov/26089364
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Four brief periods of myocardial ischemia cause no cumulative ATP loss or necrosis
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/26089364
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
The role of Na+/H+ exchange and growth factors in pulmonary artery smooth muscle cell proliferation
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/26089364
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Observations on the Pulmonary Arterial Blood Pressure in the Cat
1 reference
stated in
COCI
retrieved
12 October 2022
reference URL
https://opencitations.net/index/coci/api/v1/references/10.1161/CIRCRESAHA.117.305109
Identifiers
DOI
10.1161/CIRCRESAHA.117.305109
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
1900883
Fatcat ID
release_l4im36uapreqnngtiszk5ue6gu
0 references
OpenCitations bibliographic resource ID
1900883
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
1900883
PMC publication ID
4501273
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
1900883
PubMed publication ID
26089364
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
1900883
ResearchGate publication ID
278731100
0 references
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