(Q34044691)

30 July 2017

Aberrant RNA splicing in cancer; expression changes and driver mutations of splicing factor genes (English)

1 reference

30 July 2017

4

R A Lothe

1 reference

30 July 2017

5

R I Skotheim

1 reference

30 July 2017

A Sveen

1

1 reference

30 July 2017

S Kilpinen

series ordinal

2

1 reference

30 July 2017

A Ruusulehto

series ordinal

3

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30 July 2017

language of work or name

English

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publication date

24 August 2015

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30 July 2017

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30 July 2017

35

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30 July 2017

2413-2427

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30 July 2017

19

1 reference

https://scigraph.springernature.com/pub.10.1038/onc.2015.318

30 July 2017

0 references

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Alternative splicing in angiogenesis: the vascular endothelial growth factor paradigm

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Anti-tumor activity of splice-switching oligonucleotides

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bcl-x, a bcl-2-related gene that functions as a dominant regulator of apoptotic cell death

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Increased Rac1b expression sustains colorectal tumor cell survival

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The Rac1 splice form Rac1b promotes K-ras-induced lung tumorigenesis

31 March 2020

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Rac1b and reactive oxygen species mediate MMP-3-induced EMT and genomic instability

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Alternative splicing of BRAF transcripts and characterization of C-terminally truncated B-Raf isoforms in colorectal cancer

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RAF inhibitor resistance is mediated by dimerization of aberrantly spliced BRAF(V600E)

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Alternative splicing in cancer: implications for biology and therapy

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Alternative splicing in cancer: noise, functional, or systematic?

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A global view of cancer-specific transcript variants by subtractive transcriptome-wide analysis

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Identification of differentially regulated splice variants and novel exons in glial brain tumors using exon expression arrays.

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Alternative splicing and differential gene expression in colon cancer detected by a whole genome exon array.

31 March 2020

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Alternative splicing in colon, bladder, and prostate cancer identified by exon array analysis

31 March 2020

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Whole genome exon arrays identify differential expression of alternatively spliced, cancer-related genes in lung cancer.

31 March 2020

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Gene expression and isoform variation analysis using Affymetrix Exon Arrays

31 March 2020

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Exon-level microarray analyses identify alternative splicing programs in breast cancer

31 March 2020

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31 March 2020

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RNA sequencing of cancer reveals novel splicing alterations

31 March 2020

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An EMT-driven alternative splicing program occurs in human breast cancer and modulates cellular phenotype

31 March 2020

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Transcriptome characterization by RNA sequencing identifies a major molecular and clinical subdivision in chronic lymphocytic leukemia

31 March 2020

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Transcriptome sequencing reveals potential mechanism of cryptic 3' splice site selection in SF3B1-mutated cancers

31 March 2020

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A pan-cancer analysis of transcriptome changes associated with somatic mutations in U2AF1 reveals commonly altered splicing events

31 March 2020

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Detection of recurrent alternative splicing switches in tumor samples reveals novel signatures of cancer

31 March 2020

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Splicing mutation analysis reveals previously unrecognized pathways in lymph node-invasive breast cancer

31 March 2020

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Widespread intron retention diversifies most cancer transcriptomes

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Systematic evaluation of spliced alignment programs for RNA-seq data

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Cancer-associated regulation of alternative splicing

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Splice variants as cancer biomarkers

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Transcriptome instability in colorectal cancer identified by exon microarray analyses: Associations with splicing factor expression levels and patient survival

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Transcriptome instability as a molecular pan-cancer characteristic of carcinomas

31 March 2020

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Therapeutic potential of splice-switching oligonucleotides

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CD20 alternative splicing isoform generates immunogenic CD4 helper T epitopes.

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Splicing regulation: from a parts list of regulatory elements to an integrated splicing code

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A comprehensive survey of non-canonical splice sites in the human transcriptome.

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Genome and transcriptome sequencing of lung cancers reveal diverse mutational and splicing events.

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A day in the life of the spliceosome

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Human splicing factor SF3a, but not SF1, is essential for pre-mRNA splicing in vivo

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Integrative genome-wide analysis reveals cooperative regulation of alternative splicing by hnRNP proteins

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Building specificity with nonspecific RNA-binding proteins

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Context-dependent control of alternative splicing by RNA-binding proteins

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The emerging role of splicing factors in cancer

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Systematic bioinformatic analysis of expression levels of 17,330 human genes across 9,783 samples from 175 types of healthy and pathological tissues

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The Cancer Genome Atlas Pan-Cancer analysis project

31 March 2020

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The gene encoding the splicing factor SF2/ASF is a proto-oncogene

31 March 2020

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An integrative analysis of colon cancer identifies an essential function for PRPF6 in tumor growth

31 March 2020

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The splicing factor SRSF6 is amplified and is an oncoprotein in lung and colon cancers

31 March 2020

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Alternative splicing: aberrant splicing promotes colon tumour growth

31 March 2020

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Splicing factor hnRNPH drives an oncogenic splicing switch in gliomas

31 March 2020

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The RNA-binding protein Rbfox2: an essential regulator of EMT-driven alternative splicing and a mediator of cellular invasion

31 March 2020

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RBFOX2 is an important regulator of mesenchymal tissue-specific splicing in both normal and cancer tissues.

31 March 2020

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The splicing factor RBM4 controls apoptosis, proliferation, and migration to suppress tumor progression

31 March 2020

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Deregulation of splicing factors and breast cancer development.

31 March 2020

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Identification of novel deregulated RNA metabolism-related genes in non-small cell lung cancer.

31 March 2020

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Candidate metastasis suppressor genes uncovered by array comparative genomic hybridization in a mouse allograft model of prostate cancer

31 March 2020

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DEAD-box proteins: the driving forces behind RNA metabolism

31 March 2020

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DDX39, upregulated in lung squamous cell cancer, displays RNA helicase activities and promotes cancer cell growth

31 March 2020

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Clinical proteomics identified ATP-dependent RNA helicase DDX39 as a novel biomarker to predict poor prognosis of patients with gastrointestinal stromal tumor.

31 March 2020

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DDX39 acts as a suppressor of invasion for bladder cancer

31 March 2020

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The CELF family of RNA binding proteins is implicated in cell-specific and developmentally regulated alternative splicing

31 March 2020

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Reduced Expression of RNA Binding Protein CELF2, a Putative Tumor Suppressor Gene in Colon Cancer

31 March 2020

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Involvement of splicing factor-1 in beta-catenin/T-cell factor-4-mediated gene transactivation and pre-mRNA splicing.

31 March 2020

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Identification of genes periodically expressed in the human cell cycle and their expression in tumors

31 March 2020

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Global properties and functional complexity of human gene regulatory variation

31 March 2020

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The role of regulatory variation in complex traits and disease

31 March 2020

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Higher gene expression variability in the more aggressive subtype of chronic lymphocytic leukemia

31 March 2020

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Non-genetic heterogeneity--a mutation-independent driving force for the somatic evolution of tumours.

31 March 2020

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Overexpression of RNA-binding protein CELF1 prevents apoptosis and destabilizes pro-apoptotic mRNAs in oral cancer cells

31 March 2020

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The Gemin6-Gemin7 heterodimer from the survival of motor neurons complex has an Sm protein-like structure

31 March 2020

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Two distinct arginine methyltransferases are required for biogenesis of Sm-class ribonucleoproteins

31 March 2020

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A cyclophilin functions in pre-mRNA splicing

31 March 2020

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Genome evolution predicts genetic interactions in protein complexes and reveals cancer drug targets.

31 March 2020

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PRMT7 induces epithelial-to-mesenchymal transition and promotes metastasis in breast cancer

31 March 2020

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Fusion of splicing factor genes PSF and NonO (p54nrb) to the TFE3 gene in papillary renal cell carcinoma

31 March 2020

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Mutational landscape and significance across 12 major cancer types

31 March 2020

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Emerging patterns of somatic mutations in cancer

31 March 2020

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Frequent pathway mutations of splicing machinery in myelodysplasia

31 March 2020

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Exome sequencing identifies recurrent mutations of the splicing factor SF3B1 gene in chronic lymphocytic leukemia

31 March 2020

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SF3B1 and other novel cancer genes in chronic lymphocytic leukemia

31 March 2020

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Comprehensive molecular portraits of human breast tumours

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.318

Pancreatic cancer genomes reveal aberrations in axon guidance pathway genes

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.318

SF3B1 mutations are associated with alternative splicing in uveal melanoma

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.318

Recurrent mutations at codon 625 of the splicing factor SF3B1 in uveal melanoma.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.318

Splice factor mutations and alternative splicing as drivers of hematopoietic malignancy

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.318

Acquired mutations that affect pre-mRNA splicing in hematologic malignancies and solid tumors

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.318

Mapping the hallmarks of lung adenocarcinoma with massively parallel sequencing

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.318

U2AF1 mutations in Chinese patients with acute myeloid leukemia and myelodysplastic syndrome

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.318

Mutant U2AF1 Expression Alters Hematopoiesis and Pre-mRNA Splicing In Vivo

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.318

Comprehensive molecular profiling of lung adenocarcinoma

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.318

Analysis of next-generation genomic data in cancer: accomplishments and challenges

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.318

Mutational heterogeneity in cancer and the search for new cancer-associated genes

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.318

31 March 2020

Cancer genome landscapes

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.318

Lessons from the cancer genome

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.318

From human genome to cancer genome: the first decade

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.318

Comprehensive genomic characterization of squamous cell lung cancers

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.318

MuSiC: identifying mutational significance in cancer genomes

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.318

A landscape of driver mutations in melanoma

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.318

OncodriveCLUST: exploiting the positional clustering of somatic mutations to identify cancer genes

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.318

Functional impact bias reveals cancer drivers

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.318

Systematic analysis of somatic mutations in phosphorylation signaling predicts novel cancer drivers

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.318

Cancer-specific high-throughput annotation of somatic mutations: computational prediction of driver missense mutations

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.318

Comprehensive identification of mutational cancer driver genes across 12 tumor types

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.318

A germline mutation in SRRM2, a splicing factor gene, is implicated in papillary thyroid carcinoma predisposition

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.318

In silico prescription of anticancer drugs to cohorts of 28 tumor types reveals targeting opportunities

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.318

Fusion gene microarray reveals cancer type-specificity among fusion genes

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.318

The myxoid liposarcoma FUS-DDIT3 fusion oncoprotein deregulates NF-kappaB target genes by interaction with NFKBIZ.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.318

Gene fusions associated with recurrent amplicons represent a class of passenger aberrations in breast cancer

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.318

Cancer-associated splicing variant of tumor suppressor AIMP2/p38: pathological implication in tumorigenesis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.318

CEACAM1-3S Drives Melanoma Cells into NK Cell-Mediated Cytolysis and Enhances Patient Survival

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.318

Tumor-specific isoform switch of the fibroblast growth factor receptor 2 underlies the mesenchymal and malignant phenotypes of clear cell renal cell carcinomas

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.318

Regulation of apoptosis by alternative pre-mRNA splicing

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.318

Up-regulation of the proapoptotic caspase 2 splicing isoform by a candidate tumor suppressor, RBM5

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.318

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.318

Characterization of caspase-8L: a novel isoform of caspase-8 that behaves as an inhibitor of the caspase cascade

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.318

Alternative splicing variants of c-FLIP transduce the differential signal through the Raf or TRAF2 in TNF-induced cell proliferation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.318

Targeting the Anti-Apoptotic Protein c-FLIP for Cancer Therapy

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.318

Modification of alternative splicing of Mcl-1 pre-mRNA using antisense morpholino oligonucleotides induces apoptosis in basal cell carcinoma cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.318

Alternative and aberrant splicing of MDM2 mRNA in human cancer

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.318

Identification of an exon 4-deletion variant of epidermal growth factor receptor with increased metastasis-promoting capacity

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.318

Alternative splicing of fibroblast growth factor receptor 2 (FGF-R2) in human prostate cancer

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.318

Expression of the H-ras proto-oncogene is controlled by alternative splicing

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.318

Four human ras homologs differ in their abilities to activate Raf-1, induce transformation, and stimulate cell motility

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.318

Differential expression of novel naturally occurring splice variants of PTEN and their functional consequences in Cowden syndrome and sporadic breast cancer

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.318

Modulation of p53β and p53γ expression by regulating the alternative splicing of TP53 gene modifies cellular response

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.318

Cyclin D1: polymorphism, aberrant splicing and cancer risk

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.318

A splicing mutation in RB1 in low penetrance retinoblastoma

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.318

Mechanism for elimination of a tumor suppressor: aberrant splicing of a brain-specific exon causes loss of function of Bin1 in melanoma.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.318

Lineage-specific splicing of a brain-enriched alternative exon promotes glioblastoma progression

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.318

Expression analysis and functional activity of interleukin-7 splice variants

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.318

IL-7 splicing variant IL-7δ5 induces human breast cancer cell proliferation via activation of PI3K/Akt pathway

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.318

Switch of HLA-G alternative splicing in a melanoma cell line causes loss of HLA-G1 expression and sensitivity to NK lysis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.318

Alternative splicing regulation of telomerase: a new paradigm?

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.318

The major reverse transcriptase-incompetent splice variant of the human telomerase protein inhibits telomerase activity but protects from apoptosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.318

CD44: from adhesion molecules to signalling regulators

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.318

A new variant of glycoprotein CD44 confers metastatic potential to rat carcinoma cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.318

CEACAM1: contact-dependent control of immunity

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.318

Alternative splicing in fibroblast growth factor receptor 2 is associated with induced epithelial-mesenchymal transition in rat bladder carcinoma cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.318

Epithelial-mesenchymal transition: focus on metastatic cascade, alternative splicing, non-coding RNAs and modulating compounds

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.318

KLF6-SV1 drives breast cancer metastasis and is associated with poor survival

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.318

A non-secretory form of FAM3B promotes invasion and metastasis of human colon cancer cells by upregulating Slug expression

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.318

Molecular mechanisms of epithelial-mesenchymal transition

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.318

Cell motility is controlled by SF2/ASF through alternative splicing of the Ron protooncogene

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.318

Involvement of large tenascin-C splice variants in breast cancer progression

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.318

Identification of invasion specific splice variants of the cytoskeletal protein Mena present in mammary tumor cells during invasion in vivo.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.318

The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.318

EGFR mutation-induced alternative splicing of Max contributes to growth of glycolytic tumors in brain cancer

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.318

Metabolic reprogramming: a cancer hallmark even warburg did not anticipate

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.318

Analysis of glutamine dependency in non-small cell lung cancer: GLS1 splice variant GAC is essential for cancer cell growth

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.318

The truncated splice variant of peroxisome proliferator-activated receptor alpha, PPARα-tr, autonomously regulates proliferative and pro-inflammatory genes

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.318

HnRNP A1/A2 and SF2/ASF regulate alternative splicing of interferon regulatory factor-3 and affect immunomodulatory functions in human non-small cell lung cancer cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.318

Antitumorigenic potential of STAT3 alternative splicing modulation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.318

Redox regulation in stem-like cancer cells by CD44 variant isoforms.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.318

Human MRE11 is inactivated in mismatch repair-deficient cancers

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.318

Novel splicing associations of hereditary colon cancer related DNA mismatch repair gene mutations.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.318

Castration resistance in human prostate cancer is conferred by a frequently occurring androgen receptor splice variant

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.318

Fibronectins in vascular morphogenesis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.318

Androgen Receptor Splice Variant 7 and Efficacy of Taxane Chemotherapy in Patients With Metastatic Castration-Resistant Prostate Cancer

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.318

A common BIM deletion polymorphism mediates intrinsic resistance and inferior responses to tyrosine kinase inhibitors in cancer

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.318

Silencing survivin splice variant 2B leads to antitumor activity in taxane--resistant ovarian cancer

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.318

Overexpression of caspase-3s splice variant in locally advanced breast carcinoma is associated with poor response to neoadjuvant chemotherapy

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.318

CD22ΔE12 as a molecular target for corrective repair using RNA trans-splicing: anti-leukemic activity of a rationally designed RNA trans-splicing molecule

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.318

Claudin-18 splice variant 2 is a pan-cancer target suitable for therapeutic antibody development

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.318

An N-terminal truncated carboxypeptidase E splice isoform induces tumor growth and is a biomarker for predicting future metastasis in human cancers

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.318

A Comprehensive Analysis of CXCL12 Isoforms in Breast Cancer(1,2.)

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.318

EGFRvIII and DNA double-strand break repair: a molecular mechanism for radioresistance in glioblastoma

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.318

Epidermal growth factor receptor variant III mutations in lung tumorigenesis and sensitivity to tyrosine kinase inhibitors

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.318

Prognostic impact of alternative splicing-derived hMENA isoforms in resected, node-negative, non-small-cell lung cancer.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.318

GP369, an FGFR2-IIIb-specific antibody, exhibits potent antitumor activity against human cancers driven by activated FGFR2 signaling

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.318

Fibroblast growth factor receptor 2 IIIc as a therapeutic target for colorectal cancer cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.318

Identification of latent biomarkers in hepatocellular carcinoma by ultra-deep whole-transcriptome sequencing

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.318

Therapeutic vaccination against fibronectin ED-A attenuates progression of metastatic breast cancer

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.318

Aberrant splicing of folylpolyglutamate synthetase as a novel mechanism of antifolate resistance in leukemia.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.318

Hypoxia inducible factor 1alpha gene (HIF-1alpha) splice variants: potential prognostic biomarkers in breast cancer.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.318

Expression of spliced oncogenic Ikaros isoforms in Philadelphia-positive acute lymphoblastic leukemia patients treated with tyrosine kinase inhibitors: implications for a new mechanism of resistance

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.318

Increased alternative splicing of the KLF6 tumour suppressor gene correlates with prognosis and tumour grade in patients with pancreatic cancer.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.318

Alternative splicing variant of kallikrein-related peptidase 8 as an independent predictor of unfavorable prognosis in lung cancer

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.318

Overexpression of Mcl-1L splice variant is associated with poor prognosis and chemoresistance in oral cancers

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.318

Alternate splicing of the p53 inhibitor HDMX offers a superior prognostic biomarker than p53 mutation in human cancer.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.318

Activation of MET via diverse exon 14 splicing alterations occurs in multiple tumor types and confers clinical sensitivity to MET inhibitors

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.318

Gemcitabine triggers a pro-survival response in pancreatic cancer cells through activation of the MNK2/eIF4E pathway.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.318

Expression of variant isoforms of the tyrosine kinase SYK determines the prognosis of hepatocellular carcinoma.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.318

Regulation of telomerase alternative splicing: a target for chemotherapy

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.318

Association between VEGF splice isoforms and progression-free survival in metastatic colorectal cancer patients treated with bevacizumab

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.318

HE4 transcription- and splice variants-specific expression in endometrial cancer and correlation with patient survival.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.318

Identification and characterization of the CDK12/cyclin L1 complex involved in alternative splicing regulation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.318

Splicing switch of an epigenetic regulator by RNA helicases promotes tumor-cell invasiveness

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.318

The transcription-splicing protein NonO/p54nrb and three NonO-interacting proteins bind to distal enhancer region and augment rhodopsin expression

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.318

Mutations of the SF3B1 splicing factor in chronic lymphocytic leukemia: association with progression and fludarabine-refractoriness

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.318

The clinical significance of NOTCH1 and SF3B1 mutations in the UK LRF CLL4 trial.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.318

Recurrent mutations in the U2AF1 splicing factor in myelodysplastic syndromes

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.318

Patterns of missplicing due to somatic U2AF1 mutations in myeloid neoplasms

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.318

WT1 interacts with the splicing factor U2AF65 in an isoform-dependent manner and can be incorporated into spliceosomes

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.318

Integrative analysis revealed the molecular mechanism underlying RBM10-mediated splicing regulation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.318

Massively parallel sequencing of exons on the X chromosome identifies RBM10 as the gene that causes a syndromic form of cleft palate

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.318

Cornelia de Lange syndrome mutations in SMC1A or SMC3 affect binding to DNA

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.318

The SRm160/300 splicing coactivator subunits

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.318

SRRM2, a potential blood biomarker revealing high alternative splicing in Parkinson's disease

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2015.318

Serum soluble fas level as a prognostic factor in patients with gynecological malignancies

31 March 2020

1 reference

12 December 2020

Expression of a splice variant of KAI1, a tumor metastasis suppressor gene, influences tumor invasion and progression

1 reference

12 December 2020

Spliceosome Structure and Function

1 reference

12 December 2020

Alternative and aberrant messenger RNA splicing of the mdm2 oncogene in invasive breast cancer

1 reference

12 December 2020

Targeting the intracellular WT1 oncogene product with a therapeutic human antibody.

1 reference

12 December 2020

Multiple splice variants of lactate dehydrogenase C selectively expressed in human cancer.

1 reference

12 December 2020

Alternative mRNA splicing of liver intestine-cadherin in hepatocellular carcinoma.

1 reference

12 December 2020

MSEA: detection and quantification of mutation hotspots through mutation set enrichment analysis

1 reference

12 December 2020

A novel splice variant of the Fas gene in patients with cutaneous T-cell lymphoma

1 reference

12 December 2020

Fibroblast growth factor receptor 2 limits and receptor 1 accelerates tumorigenicity of prostate epithelial cells

1 reference

12 December 2020

Transformational and altered signal transduction by a naturally occurring mutant EGF receptor

1 reference

12 December 2020

K-ras 4A and 4B are co-expressed widely in human tissues, and their ratio is altered in sporadic colorectal cancer

1 reference

12 December 2020

An alternatively spliced cadherin-11 enhances human breast cancer cell invasion

1 reference

12 December 2020

Uncovering the role of p53 splice variants in human malignancy: a clinical perspective

1 reference

12 December 2020

Identifiers

DOI

10.1038/ONC.2015.318

1 reference

Dimensions Publication ID

30 July 2017

0 references

1 reference